1. Fatal gastritis and enterocolitis due to concurrent Helicobacter pylori and Campylobacter jejuni infection in a captive cheetah (Acinonyxjubatus).
- Author
-
Zingre T, Bagatella S, Wenker C, Kittl S, Meli ML, Wyss F, and Grau-Roma L
- Subjects
- Female, Animals, Gastric Mucosa pathology, Helicobacter pylori, Acinonyx microbiology, Campylobacter jejuni, Gastritis microbiology, Gastritis pathology, Gastritis veterinary, Helicobacter Infections complications, Helicobacter Infections pathology, Helicobacter Infections veterinary, Enterocolitis complications, Enterocolitis veterinary
- Abstract
A 3.5-year-old female cheetah (Acinonyx jubatus) died after a 10-day history of anorexia, regurgitation and diarrhoea despite symptomatic therapy. At gross post-mortem examination, the stomach was blood-filled with mucosal thickening and multifocal ulcerations. The intestinal mucosa was thickened and reddened, and the intestinal lumen was filled with dark red to black pasty content. Gastric histological lesions were compatible with gastritis due to Helicobacter infection, which was confirmed by polymerase chain reaction. Histology of the intestines revealed a severe necrotizing neutrophilic enterocolitis with abundant intralesional curved to spiral bacteria, corresponding to Campylobacter jejuni, which were subsequently isolated from both small and large intestinal contents. No other intestinal pathogens were detected despite thorough investigations. These findings suggest that C. jejuni may have played an aetiological role in the enterocolitis. Such an association has not been previously reported in non-domestic felids., (Copyright © 2023 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
- Published
- 2023
- Full Text
- View/download PDF