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222 results on '"Accurso, Antonello"'

1. Clinical value of radiomics and machine learning in breast ultrasound: a multicenter study for differential diagnosis of benign and malignant lesions

Author

Romeo, Valeria, Cuocolo, Renato, Apolito, Roberta, Stanzione, Arnaldo, Ventimiglia, Antonio, Vitale, Annalisa, Verde, Francesco, Accurso, Antonello, Amitrano, Michele, Insabato, Luigi, Gencarelli, Annarita, Buonocore, Roberta, Argenzio, Maria Rosaria, Cascone, Anna Maria, Imbriaco, Massimo, Maurea, Simone, and Brunetti, Arturo

Published
2021
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6. New techniques versus standard mapping for sentinel lymph node biopsy in breast cancer: a systematic review and meta-analysis.

Author

Rocco, Nicola, Velotti, Nunzio, Pontillo, Martina, Vitiello, Antonio, Berardi, Giovanna, Accurso, Antonello, Masone, Stefania, and Musella, Mario

Abstract

New tracers for sentinel lymph node biopsy (SLNB), as indocyanine green (ICG), superparamagnetic iron oxide (SPIO) and micro bubbles, have been recently introduced in clinical practice showing promising but variable results. We reviewed the available evidence comparing these new techniques with the standard tracers to evaluate their safety. To identify all available studies, a systematic search was performed in all electronic databases. Data regarding sample size, mean number of SLN harvested for patient, number of metastatic SLN and SLN identification rate of all studies were extracted. No significant differences were found in terms of SLNs identification rates between SPIO, RI and BD but with a higher identification rate with the use of ICG. No significant differences were also found for the number of metastatic lymph nodes identified between SPIO, RI and BD and the mean number of SLNs identified between SPIO and ICG versus conventional tracers. A statistically significant differences in favor of ICG was reported for the comparison between ICG and conventional tracers for the number of metastatic lymph nodes identified. Our meta-analysis demonstrates that the use of both ICG and SPIO for the pre-operative mapping of sentinel lymph nodes in breast cancer treatment is adequately effective. [ABSTRACT FROM AUTHOR]

Published
2023
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7. Contralateral risk reducing mastectomy in Non-BRCA-Mutated patients

Author

Falco Giuseppe, Rocco Nicola, Bordoni Daniele, Marano Luigi, Accurso Antonello, Buccelli Claudio, Di Lorenzo Pierpaolo, Capasso Emanuele, Policino Fabio, Niola Massimo, and Ferrari Guglielmo

Subjects
Breast Cancer, contralateral risk reducing mastectomy, Non-mutated patients, Medicine
Abstract

The use of contralateral risk reducing mastectomy (CRRM) is indicated in women affected by breast cancer, who are at high risk of developing a contralateral breast cancer, particularly women with genetic mutation of BRCA1, BRCA2 and P53. However we should consider that the genes described above account for only 20-30% of the excess familiar risk. What is contralaterally indicated when genetic assessment results negative for mutation in a young patient with unilateral breast cancer? Is it ethically correct to remove a contralateral “healthy” breast? CRRM rates continue to rise all over the world although CRRM seems not to improve overall survival in women with unilateral sporadic breast cancer. The decision to pursue CRRM as part of treatment in women who have a low-to-moderate risk of developing a secondary cancer in the contralateral breast should consider both breast cancer individual-features and patients preferences, but should be not supported by the surgeon and avoided as first approach with the exception of women highly worried about cancer. Prospective studies are needed to identify cohorts of patients most likely to benefit from CRRM.

Published
2016
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15. Generation and Characterization of a Tumor Stromal Microenvironment and Analysis of Its Interplay with Breast Cancer Cells: An In Vitro Model to Study Breast Cancer-Associated Fibroblast Inactivation

Author

Romano, Veronica, primary, Ruocco, Maria Rosaria, additional, Carotenuto, Pietro, additional, Barbato, Anna, additional, Venuta, Alessandro, additional, Acampora, Vittoria, additional, De Lella, Sabrina, additional, Vigliar, Elena, additional, Iaccarino, Antonino, additional, Troncone, Giancarlo, additional, Calì, Gaetano, additional, Insabato, Luigi, additional, Russo, Daniela, additional, Franco, Brunella, additional, Masone, Stefania, additional, Velotti, Nunzio, additional, Accurso, Antonello, additional, Pellegrino, Tommaso, additional, Fiume, Giuseppe, additional, Belviso, Immacolata, additional, Montagnani, Stefania, additional, Avagliano, Angelica, additional, and Arcucci, Alessandro, additional

Published
2022
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17. Epithelioid hemangioma of brachial artery: report of a case and review of the literature

Author

Ragazzi Moira, Falco Giuseppe, Valli Riccardo, Rocco Nicola, Bordoni Daniele, Cadenelli Pierfrancesco, Della Corte Gianni Antonio, Accurso Antonello, Amato Bruno, Casali Giovanni, and Ferrari Guglielmo

Subjects
Epithelioid Hemangioma, Brachial Artery, Medicine
Abstract

Epithelioid hemangioma (EH) is an uncommon benign vascular lesion, also known as angioblastic lymphoid (or angiolymphoid) hyperplasia with eosinophilia, characterized by an unclear etiopathogenesis.

Published
2015
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21. Additive manufacturing and technical strategies for improving outcomes in breast reconstructive surgery

Author

Rocco, Nicola, primary, Papallo, Ida, additional, Nava, Maurizio Bruno, additional, Catanuto, Giuseppe, additional, Accurso, Antonello, additional, Onofrio, Ilaria, additional, Oliviero, Olimpia, additional, Improta, Giovanni, additional, Speranza, Domenico, additional, Domingos, Marco, additional, Russo, Teresa, additional, De Santis, Roberto, additional, Martorelli, Massimo, additional, and Gloria, Antonio, additional

Published
2020
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23. Breast implant associated anaplastic large cell lymphoma (BIA-ALCL): a challenging cytological diagnosis with hybrid PET/MRI staging and follow-up

Author

Verde, Francesco, primary, Vigliar, Elena, additional, Romeo, Valeria, additional, Campanino, Maria Raffaela, additional, Accurso, Antonello, additional, Canta, Luigi, additional, Garbino, Nunzia, additional, Basso, Luca, additional, Cavaliere, Carlo, additional, Nicolai, Emanuele, additional, and Imbriaco, Massimo, additional

Published
2020
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24. The continuing role of breast fine‐needle aspiration biopsy after the introduction of the IAC Yokohama System For Reporting Breast Fine Needle Aspiration Biopsy Cytopathology

Author

De Rosa, Filippo, primary, Migliatico, Ilaria, additional, Vigliar, Elena, additional, Salatiello, Maria, additional, Pisapia, Pasquale, additional, Iaccarino, Antonino, additional, Russo, Daniela, additional, Insabato, Luigi, additional, Accurso, Antonello, additional, Arpino, Grazia, additional, Palombini, Lucio, additional, Troncone, Giancarlo, additional, and Bellevicine, Claudio, additional

Published
2020
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25. Influence of Fibroblasts on Mammary Gland Development, Breast Cancer Microenvironment Remodeling, and Cancer Cell Dissemination

Author

Avagliano, Angelica, primary, Fiume, Giuseppe, additional, Ruocco, Maria Rosaria, additional, Martucci, Nunzia, additional, Vecchio, Eleonora, additional, Insabato, Luigi, additional, Russo, Daniela, additional, Accurso, Antonello, additional, Masone, Stefania, additional, Montagnani, Stefania, additional, and Arcucci, Alessandro, additional

Published
2020
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26. Tumor segmentation analysis at different post-contrast time points: A possible source of variability of quantitative DCE-MRI parameters in locally advanced breast cancer

Author

Romeo, Valeria, primary, Cavaliere, Carlo, additional, Imbriaco, Massimo, additional, Verde, Francesco, additional, Petretta, Mario, additional, Franzese, Monica, additional, Stanzione, Arnaldo, additional, Cuocolo, Renato, additional, Aiello, Marco, additional, Basso, Luca, additional, Amitrano, Michele, additional, Lauria, Rossella, additional, Accurso, Antonello, additional, Brunetti, Arturo, additional, and Salvatore, Marco, additional

Published
2020
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27. Palbociclib added to ongoing endocrine therapy for hormone receptor‑positive HER2‑negative metastatic breast cancer: A case report series

Author

Schettini, Francesco, primary, De Santo, Irene, additional, Rea, Carmen, additional, Viggiani, Martina, additional, Buono, Giuseppe, additional, De Angelis, Carmine, additional, Cardalesi, Cinzia, additional, Lauria, Rossella, additional, Giuliano, Mario, additional, Forestieri, Valeria, additional, Thomas, Guglielmo, additional, Maione, Pierfrancesco, additional, Limite, Gennaro, additional, Accurso, Antonello, additional, Malorni, Luca, additional, De Placido, Sabino, additional, and Arpino, Grazia, additional

Published
2020
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29. Therapeutic mammaplasty is a safe and effective alternative to mastectomy with or without immediate breast reconstruction

Author

Potter, S, primary, Trickey, A, additional, Rattay, T, additional, O'Connell, R L, additional, Dave, R, additional, Baker, E, additional, Whisker, L, additional, Skillman, J, additional, Gardiner, M D, additional, Macmillan, R D, additional, Holcombe, C, additional, Potter, S, additional, Barnes, Nicola L P, additional, Blazeby, Jane, additional, Conroy, Elizabeth, additional, Dave, Rajiv V, additional, Gardiner, Matthew D, additional, Harnett, Adrian, additional, Holcombe, Chris, additional, Potter, Shelley, additional, Rattay, Tim, additional, Skillman, Joanna, additional, Williamson, Paula, additional, Achuthan, Rajgopal, additional, Aggarwal, Shweta, additional, Baker, Elizabeth, additional, Basu, Naren, additional, Brock, Lisa, additional, Fairbrother, Patricia, additional, Ives, Charlotte, additional, Jain, Abhilash, additional, Kim, Baek, additional, Macmillan, R Douglas, additional, Murphy, John, additional, Remoundos, Dennis, additional, Sutton, Richard, additional, Trickey, Adam, additional, Turton, Philip, additional, Williams, Kathryn, additional, Curnier, Alain, additional, Tadros, Amir, additional, Depasquale, Ivan, additional, Fuller, Mairi, additional, Bourne, Roger, additional, Heys, Steven, additional, Hamo, Ishrak, additional, Aloraifi, Fatima, additional, Fopp, Laura, additional, Bali, Radhika, additional, Bache, Sarah, additional, Benyon, Sarah L, additional, Irwin, Michael S, additional, Agrawal, Amit, additional, Malata, Charles M, additional, Murphy, Claire, additional, Misky, Adam, additional, Chicken, Dennis Wayne, additional, Abdullah, Nassreen, additional, Hill, Arnold D K, additional, Cullinane, Carolyn, additional, Irwin, Gareth, additional, McIntosh, Stuart A, additional, Refsum, Sigi, additional, Sloan, Samantha, additional, Mallon, Peter, additional, Sirianni, Chiara, additional, Khattak, Ilyas, additional, Nagachandra, Geerthan, additional, Kiruparan, Pasupathy, additional, Debanth, Debasish, additional, Davey, Simon, additional, Curran, Terry-Ann, additional, Svenning, Matilda, additional, Govindarajulu, Sasirekha, additional, Rayter, Zenon, additional, Ainsworth, Rachel, additional, Cawthorn, Simon, additional, Sahu, Ajay, additional, Wilson, Sherif, additional, Prousskaia, Elena, additional, Accurso, Antonello, additional, Rocco, Nicola, additional, Di Micco, Rosa, additional, Limite, Gennaro, additional, Ceccarino, Raffaele, additional, Liccardo, Raffaele, additional, Coco, Guido, additional, Nizamoglu, Metin, additional, Morgan, Mary, additional, Ramakrishnan, Venkat, additional, Catanuto, Giuseppe, additional, Wilkins, Alex, additional, McManus, Penelope, additional, Kneeshaw, Peter, additional, Grover, Kartikae, additional, Mahapatra, Tapan, additional, Wooler, Brendan, additional, Elahi, Bilal, additional, Ihsan, Naila, additional, Bucknor, Alexandra, additional, Reissis, Dimitris, additional, Hunter, Judith, additional, Wood, Simon, additional, Jallali, Navid, additional, Henry, Francis P, additional, Verjee, Liaquat S, additional, Lee, Jason, additional, Khan, Shazia M, additional, Azmy, Iman, additional, Massey, Julia, additional, Hollywood, Ciaran, additional, Oluwajana, Michael, additional, Bathla, Sonia, additional, Seward, Joanna, additional, Harding-MacKean, Claudia, additional, Lane, Risha, additional, Murali, Kothandaraman, additional, Biswas, Bashishta, additional, Trapszo, Pawel, additional, Seetharam, Seema, additional, Kennedy, Katy, additional, Alder, Louise, additional, Graja, Tomasz, additional, Amin, Khalid, additional, Kokan, Jalal, additional, Roshanlall, Chandeena, additional, Gill, Emma, additional, Kulkarni, Dhananjay, additional, Dixon, J M, additional, Young, Oliver, additional, Saleem, Talha, additional, Biddle, M, additional, Kearns, Marie, additional, Weiler-Mithoff, Eva, additional, Chew, Ben, additional, Malyon, Andy, additional, Scott, John, additional, McGill, David, additional, Mackay, Iain, additional, Bains, Salena, additional, Barrows, Sara, additional, Pilgrim, Simon, additional, Shokuhi, Sheila, additional, Lambert, Kelly, additional, Kenny, Frances, additional, Valassiadou, Kalliope, additional, Kaushik, Monika, additional, Krupa, Jaroslaw, additional, Dragoumis, Dimitris, additional, Lampropoulos, Pavlos, additional, Moss, Sarah, additional, Khalil, Haitham, additional, Haq, Anwar, additional, Balasubramanian, Balapathiran, additional, Charalampoudis, Petros, additional, Hamed, Hisham, additional, Kothari, Ashutosh, additional, Kovacs, Tibor, additional, Douek, Michael, additional, Mehmood, Iftikhar, additional, Ray, Biswajit, additional, Adelekan, Matthew, additional, Humphreys, Laura, additional, Tayeh, Salim, additional, Choy, Christina, additional, Parvanta, Laila, additional, Michieletto, Silvia, additional, Saibene, Tania, additional, O'Brien, James, additional, Down, Sue, additional, Downey, Sarah, additional, Pereira, Jerome, additional, Sami, A S, additional, Gvaramadze, Anzors, additional, Jibril, Jibril A, additional, Thekkinkattil, Dinesh, additional, Udayasankar, S, additional, Khawaja, Saira, additional, Shariaha, Yousef, additional, Holt, Simon, additional, James, Ruth, additional, Rizki, Hirah, additional, Kirkpatrick, Katharine, additional, Ravichandran, Duraisamy, additional, Shrestha, Deepak, additional, Barua, Ellora, additional, Akolekar, Deepika, additional, Hamad, Ahmed, additional, Kleidi, Eleftheria, additional, Hignett, Susan, additional, Pope, Vanessa, additional, Naseem, Salma, additional, Isherwood, Jennifer, additional, Soulsby, Rachel, additional, Taylor, Amanda, additional, Chin, Kian, additional, Nguyen, Dai, additional, Guest, Francesca, additional, Thorne, Amanda, additional, Lefemine, Valentina, additional, Kirchhoff, Chris, additional, Murphy, Declan C, additional, Lo, Michelle, additional, Harcourt, Ruth, additional, Pain, Simon J, additional, Hussien, Maged I, additional, Zechmeister, Katalin, additional, Sassoon, E M, additional, Figus, Andrea, additional, Haywood, Richard M, additional, Ali, Rozina, additional, Alexander, Susanna, additional, Geropantas, Konstantinos, additional, Epurescu, Daniel, additional, Lewis, Rebecca, additional, Fafemi, Oladapo, additional, Gahir, Jasdeep, additional, Gandamihardja, Tasha, additional, Kelsall, Jennett, additional, Muhibullah, Nazli, additional, Otieno, Charlene, additional, Mazari, Fayyaz, additional, Dauria, Marta, additional, Whisker, Lisa, additional, Macmillan, Douglas, additional, Gutteridge, Eleanor, additional, Rasheed, Tuabin, additional, Khout, Hazem, additional, Asgeirsson, Kristjan, additional, McCulley, Stephen, additional, Mariniello, Maria Donatella, additional, Roncella, Manuela, additional, Ghilli, Matteo, additional, Colizzi, Livio, additional, Rossetti, Elena, additional, Marzia, Lo Russo, additional, Fustaino, Loredana, additional, Li, Alessandro Quattrini, additional, Harvey, Kate L, additional, Windle, Rebecca, additional, Remoundos, Dionysios Dennis, additional, Roy, Pankaj, additional, MacLean, Gael, additional, Adwani, Asha, additional, Popa, Elena, additional, Goh, Steven, additional, Shetty, Geeta, additional, Clark, Sarah, additional, Bernaudo, Lorenzo, additional, Agrawal, Avi, additional, Mansfield, Lucy, additional, Tebbal, Sally, additional, Patel, Ashraf, additional, Grassi, Veronica, additional, Pujji, Ojas, additional, Hamnett, Kathryn, additional, Granger, Emily, additional, Durbar, Michael, additional, Pikoulas, Panagiotis, additional, Garnsey, Clare, additional, Walker, Philip, additional, Vollermere, Angela J, additional, Michalakis, Ioannis, additional, Jones, Robin, additional, Youssef, Mina, additional, Masood, Mohammad, additional, Dunn, Julie, additional, Olsen, Sisse, additional, Ferguson, Douglas, additional, Tillett, Rachel, additional, Allan, Anna, additional, Woollard, Alex, additional, Canny, Rebecca, additional, Woollard, Alexander, additional, Mosahebi, Afshin, additional, Hamilton, Stephen, additional, Chana, Jagdeep, additional, Sojitra, Nilesh, additional, Younis, Ibby, additional, Rainsbury, Dick, additional, Chand, Natalie, additional, Kalles, Vasileios, additional, Stebbing, Anne, additional, Harris, Kevin, additional, Laws, Siobhan, additional, Tansley, Anne, additional, Mitchell, Geraldine, additional, de Sousa, Emma, additional, Henderson, Julia, additional, Chandrashekar, Mysore, additional, Pereira, Bernadette, additional, Constantinou, Chloe, additional, Elfadl, Dalia, additional, Irakleidis, Foivos, additional, Hernan, Izaro, additional, Byrne, Miriam, additional, O'Connell, Rachel, additional, Rusby, Jennifer, additional, Barry, Peter, additional, Krupa, Katerine, additional, Allum, William, additional, MacNeill, Fiona, additional, Roche, Nicola, additional, Gui, Gerald, additional, Ramsey, Kelvin, additional, Harris, Paul, additional, James, Stuart, additional, McIntosh, Jamie, additional, Laurence, Nicola, additional, MacLennan, Louise, additional, Milligan, Robert, additional, Cain, Henry, additional, Critchley, Adam, additional, O'Donoghue, Joe, additional, Kalra, Loraine, additional, Collis, Nick, additional, Weston-Petrides, Gina, additional, Fiddes, Roanne, additional, Brown, Victoria, additional, Aertssen, Anna, additional, Slade-Sharman, Diana, additional, Khan, Mansoor, additional, McGuiness, Caroline, additional, Amorosi, Vittoria, additional, di Pompeo Fabio, Santanelli, additional, Exarchos, Georgios, additional, Jiwa, Natasha, additional, Hu, Jennifer, additional, Ledwidge, Serena, additional, Johnson, Laura, additional, Peel, Anthony, additional, Dhooma, Naseem, additional, Farrell, Eric, additional, Devane, Liam, additional, Tevlin, Ruth, additional, McDermott, Enda, additional, Prichard, Ruth, additional, Evoy, Denis, additional, Rothwell, Jane, additional, Geraghty, James, additional, Morrison, Colin, additional, Lawlor, Catriona, additional, Langlands, Fiona, additional, Taylor, Lauren, additional, Achuthan, Raj, additional, Horgan, Kieran, additional, Mckenzie, Shireen, additional, Hogan, Brian, additional, Lansdown, Mark, additional, Navin, Channegowda, additional, Sherwin, Liz, additional, Mortimer, Caroline, additional, Garg, Neeraj, additional, Adam, Rahma, additional, Arif, Tahera, additional, Kryjak, Zbigniew, additional, Ali, Deedar, additional, Sowdi, Ravi, additional, Fage, Elena, additional, Mylvaganam, Senthurun, additional, Matey, Pilar, additional, Vidya, Raghavan, additional, Sircar, Tapan, additional, Asaad, Oubida, additional, Bhaskar, Pud, additional, Dordea, Matei, additional, Chrysafi, Ada, additional, McCartan, Damian, additional, Dave, Rajiv, additional, Foster, Rachel, additional, Wilson, Rebecca, additional, Okwemba, Sylvia, additional, Majeed, Yousef, additional, O'Brien, Ciara, additional, Mathen, Vinod, additional, Barnes, Nicola, additional, Gandhi, Ashu, additional, Harvey, James, additional, Kirwan, Cliona C, additional, Johnson, Richard, additional, Patel, Krupali, additional, Ribas, Maria Dalmau, additional, Vigneswaran, Natali, additional, Challoner, Tom, additional, Park, Alan, additional, Rizkalla, Maged, additional, Tomlins, Abigail, additional, McEvoy, Kat, additional, Jafferbhoy, Sadaf, additional, Soumian, Soni, additional, Narayanan, Sankaran, additional, Kirby, Robert, additional, Bajrusevic, Sladana, additional, Maalo, Joseph, additional, Charalambous, Michalis, additional, Lai, Lee Min, additional, Chong, Kelvin, additional, Thomson, Simon, additional, Monib, Sherif, additional, Chagla, Leena, additional, Audisio, Riccardo, additional, Taghizadeh, Rieka, additional, Iqbal, Azhar, additional, James, Karen, additional, Callaghan, Maria, additional, Poonawala, Shabbir, additional, Lund, Jonathan, additional, Vinayagam, Raman, additional, Thrush, Steven, additional, Thomas, Rachel Bright, additional, Mullan, Michelle, additional, Taylor, Jevan, additional, Yoshimura, Ryo, additional, Mathew, Tom, additional, Jones, Ben Mancey, additional, Munot, Kailas, additional, Nasr, Rana, additional, Piper, Jenny, additional, El-Sharief, Deena, additional, Mustafa, Mohammed, additional, MacLeod, Caitlin, additional, Smyth, Elizabeth, additional, Saeed, Nina, additional, Masannat, Yazan, additional, Mohd-Amin, Amir Tan, additional, Sloan, Sam, additional, McIntosh, Stuart, additional, Ibrahim, Abdulla, additional, Rathinaezhil, Rathi, additional, Khalifa, Eiman, additional, McManus, Penny, additional, Leeper, Alexander, additional, McIlhenny, Jennifer, additional, Mansell, James, additional, Ogsto, Keith, additional, Romics, Laszlo, additional, Shokuhi, Shelia, additional, Lee, Xiang Wei Jonathan, additional, Al-Allak, Asmaa, additional, Fowler, Clare, additional, Massey, Eleanore, additional, Court, Fiona, additional, Hunt, Richard, additional, Vestey, Sarah, additional, Elgammal, Mohsen, additional, Noshirwani, Arish, additional, Arif, Tehera, additional, Syed, Farah H, additional, Safdar, Gazalla, additional, El-Abbar, Mohammed, additional, Hogg, Fiona, additional, McGee, Pauline, additional, Pitsinis, Vassilis, additional, Smith, Jenny, additional, Makkiyah, Sundus, additional, Mustafa, Syed, additional, Photiou, Dana, additional, Gutteridge, Ellie, additional, Oni, Georgette, additional, Hallam, Kelly, additional, Asgeirron, Kristjan, additional, D'Auria, Marta, additional, Al-zubaidi, Samim, additional, Bailey, James, additional, Tenovici, Alexandra, additional, Remoundos, Dionysios-Dennis, additional, Chaidos, Nikos, additional, Predescu, Oana, additional, Rezulski, Jan, additional, Abdullah, Tholkifl, additional, Udayasankar, Sujatha, additional, Talbot, Adam, additional, Singh, Jagdeep, additional, Smith, Amy, additional, Volleamere, Angela, additional, Dean, Sarah, additional, Peiris, Lashan, additional, Sjokvist, Olivia, additional, De Sousa, Emma, additional, Micha, Aikaterini, additional, Godden, Amy, additional, Krupa, Katherine, additional, Henton, John, additional, Bennett, Ruth, additional, Nicholson, Stewart, additional, Paolini, Guido, additional, Renzi, Luca Francesco, additional, Di Pompeo, Santanelli, additional, Ria, Vitto, additional, Lewis, Rebecca S, additional, Hadad, Sirwan, additional, Sharma, Anup, additional, Toomey, Delia, additional, Banerjee, Dibyesh, additional, Tang, Sarah Shuk Kay, additional, McKenzie, Shireen, additional, Ahmad, Tanvir, additional, Williams, Kate, additional, Absar, Mohammed, additional, Nasir, Nabila, additional, Rychlik, Igor Jerzy, additional, Darragh, Lynn, additional, Johnston, Ruth, additional, Kirk, Stephen, additional, Rees-Lee, Jacqueline, additional, Green, Michael, additional, Sharma, Abhishek, additional, Choong, Jia, additional, Ullah, Zaker, additional, Koshy, Ommen, additional, Kiernan, Tamara, additional, Bhojwani, Ajay Ashok, additional, Bright-Thomas, Rachel, additional, Byrne, Ged, additional, Ibrahim, Ibrahim, additional, Highton, Lyndsey, additional, Morris, Owen, additional, Chatterjee, Sumohan, additional, Kirwan, Cliona, additional, Mancey-Jones, Ben, additional, El Sharief, Denna, additional, and Frame, Richard, additional

Published
2020
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30. The impact of immediate breast reconstruction on the time to delivery of adjuvant therapy: the iBRA-2 study

Author

O'Connell, Rachel L, Rattay, Tim, Dave, Rajiv V, Trickey, Adam, Skillman, Joanna, Barnes, Nicola LP, Gardiner, Matthew, Harnett, Adrian, Potter, Shelley, Holcombe, Chris, Blazeby, Jane, Conroy, Elizabeth, O'Brien, Ciara, Williamson, Paula, Curnier, Alain, Tadros, Amir, Depasquale, Ivan, Masannat, Yazan A, Smyth, Elizabeth, Fuller, Mairi, Bourne, Roger, Heys, Steven, Hamo, Ishrak, Aloraifi, Fatima, Fopp, Laura, Bali, Radhika, Bache, Sarah, Benyon, Sarah L, Irwin, Michael S, Agrawal, Amit, Malata, Charles M, Murphy, Claire, Misky, Adam, Chicken, Dennis Wayne, Abdullah, Nassreen, Hill, Arnold DK, Cullinane, Carolyn, Irwin, Gareth, McIntosh, Stuart A, Refsum, Sigi, Sloan, Samantha, Mallon, Peter, Sirianni, Chiara, Khattak, Ilyas, Nagachandra, Geerthan, Kiruparan, Pasupathy, Debanth, Debasish, Davey, Simon, Curran, Terry-Ann, Svenning, Matilda, Govindarajulu, Sasirekha, Rayter, Zenon, Ainsworth, Rachel, Cawthorn, Simon, Sahu, Ajay, Wilson, Sherif, Prousskaia, Elena, Accurso, Antonello, Rocco, Nicola, Di Micco, Rosa, Limite, Gennaro, Ceccarino, Raffaele, Liccardo, Raffaele, Coco, Guido, Nizamoglu, Metin, Morgan, Mary, Ramakrishnan, Venkat, Catanuto, Giuseppe, Wilkins, Alex, McManus, Penelope, Kneeshaw, Peter, Grover, Kartikae, Mahapatra, Tapan, Wooler, Brendan, Elahi, Bilal, Ihsan, Naila, Bucknor, Alexandra, Reissis, Dimitris, Hunter, Judith, Wood, Simon, Jallali, Navid, Henry, Francis P, Verjee, Liaquat S, Lee, Jason, Khan, Shazia M, Azmy, Iman, Massey, Julia, Hollywood, Ciaran, Oluwajana, Michael, Bathla, Sonia, Seward, Joanna, Harding-MacKean, Claudia, Lane, Risha, Murali, Kothandaraman, Biswas, Bashishta, Trapszo, Pawel, Seetharam, Seema, Kennedy, Katy, Alder, Louise, Graja, Tomasz, Amin, Khalid, Kokan, Jalal, Roshanlall, Chandeena, Gill, Emma, Kulkarni, Dhananjay, Dixon, JM, Young, Oliver, Saleem, Talha, Biddle, M, Kearns, Marie, Weiler-Mithoff, Eva, Chew, Ben, Malyon, Andy, Scott, John, McGill, David, Mackay, Iain, Bains, Salena, Barrows, Sara, Pilgrim, Simon, Shokuhi, Sheila, Lambert, Kelly, Kenny, Frances, Valassiadou, Kalliope, Kaushik, Monika, Krupa, Jaroslaw, Dragoumis, Dimitris, Ain, Quratul, Lampropoulos, Pavlos, Moss, Sarah, Khalil, Haitham, Haq, Anwar, Balasubramanian, Balapathiran, Charalampou-Dis, Petros, Hamed, Hisham, Kothari, Ashutosh, Kovacs, Tibor, Douek, Michael, Mehmood, Iftikhar, Ray, Biswajit, Adelekan, Matthew, Humphreys, Laura, Tayeh, Salim, Choy, Christina, Parvanta, Laila, Michieletto, Silvia, Saibene, Tania, O'Brien, James, Down, Sue, Downey, Sarah, Pereira, Jerome, Sami, AS, Gvaramadze, Anzors, Jibril, Jibril A, Thekkinkattil, Dinesh, Udayasankar, S, Khawaja, Saira, Shariaha, Yousef, Holt, Simon, James, Ruth, Rizki, Hirah, Kirkpatrick, Katharine, Ravichandran, Duraisamy, Shrestha, Deepak, Barua, Ellora, Akolekar, Deepika, Hamad, Ahmed, Kleidi, Eleftheria, Hignett, Susan, Pope, Vanessa, Naseem, Salma, Isherwood, Jennifer, Soulsby, Rachel, Taylor, Amanda, Chin, Kian, Nguyen, Dai, Guest, Francesca, Thorne, Amanda, Kirchhoff, Chris, Murphy, Declan C, Lo, Michelle, Harcourt, Ruth, Pain, Simon J, Hussien, Maged I, Zechmeister, Katalin, Sassoon, EM, Figus, Andrea, Haywood, Richard M, Ali, Rozina, Alexander, Susanna, Geropantas, Konstantinos, Epurescu, Daniel, Lewis, Rebecca, Fafemi, Oladapo, Gahir, Jasdeep, Gandamihardja, Tasha, Kelsall, Jennett, Muhibullah, Nazli, Otieno, Charlene, Mazari, Fayyaz, Dauria, Marta, Whisker, Lisa, Macmillan, Douglas, Gutteridge, Eleanor, Rasheed, Tuabin, Khout, Hazem, Asgeirsson, Kristjan, McCulley, Stephen, Mariniello, Maria Donatella, Roncella, Manuela, Ghilli, Matteo, Colizzi, Livio, Rossetti, Elena, Marzia, Lo Russo, Fustaino, Loredana, Li, Alessandro Quattrini, Harvey, Kate L, Windle, Rebecca, Remoundos, Dionysios Dennis, Roy, Pankaj, MacLean, Gael, Adwani, Asha, Popa, Elena, Goh, Steven, Shetty, Geeta, Clark, Sarah, Bernaudo, Lorenzo, Agrawal, Avi, Mansfield, Lucy, Tebbal, Sally, Patel, Ashraf, Grassi, Veronica, Pujji, Ojas, Hamnett, Kathryn, Basu, Naren, Granger, Emily, Durbar, Michael, Pikoulas, Panagiotis, Garnsey, Clare, Walker, Philip, Vollermere, Angela J, Michalakis, Ioannis, Jones, Robin, Youssef, Mina, Ives, Charlotte, Masood, Mohammad, Dunn, Julie, Olsen, Sisse, Ferguson, Douglas, Tillett, Rachel, Allan, Anna, Woollard, Alex, Canny, Rebecca, Woollard, Alexander, Mosahebi, Afshin, Hamilton, Stephen, Ghali, Shadi, Marsh, Daniel, Chana, Jagdeep, Sojitra, Nilesh, Younis, Ibby, Rainsbury, Dick, Chand, Natalie, Kalles, Vasileios, Stebbing, Anne, Harris, Kevin, Laws, Siobhan, Tansley, Anne, Mitchell, Geraldine, de Sousa, Emma, Henderson, Julia, Chandrashekar, Mysore, Pereira, Bernadette, Constantinou, Chloe, Elfadl, Dalia, Irakleidis, Foivos, Hernan, Izaro, Byrne, Miriam, To, Natalie, O'Connell, Rachel, Rusby, Jennifer, Barry, Peter, Krupa, Katerine, Allum, William, MacNeill, Fiona, Roche, Nicola, Gui, Gerald, Ramsey, Kelvin, Harris, Paul, James, Stuart, Power, Kieran, Sutton, Richard, McIntosh, Jamie, Laurence, Nicola, MacLennan, Louise, Milligan, Robert, Cain, Henry, Critchley, Adam, O'Donoghue, Joe, Kalra, Loraine, Collis, Nick, Weston-Petrides, Gina, Fiddes, Roanne, Brown, Victoria, Aertssen, Anna, Slade-Sharman, Diana, Khan, Mansoor, McGuiness, Caroline, Amorosi, Vittoria, Fabio, Santanelli di Pompeo, Exarchos, Georgios, Jiwa, Natasha, Hu, Jennifer, Ledwidge, Serena, Johnson, Laura, Peel, Anthony, Dhooma, Naseem, Farrell, Eric, Devane, Liam, Tevlin, Ruth, McDermott, Enda, Prichard, Ruth, Evoy, Denis, Rothwell, Jane, Geraghty, James, Morrison, Colin, Lawlor, Catriona, Langlands, Fiona, Taylor, Lauren, Turton, Philip, Achuthan, Raj, Horgan, Kieran, Mckenzie, Shireen, Hogan, Brian, Lansdown, Mark, Navin, Channegowda, Sherwin, Liz, Mortimer, Caroline, Garg, Neeraj, Adam, Rahma, Arif, Tahera, Kryjak, Zbigniew, Ali, Deedar, Sowdi, Ravi, Fage, Elena, Mylvaganam, Senthurun, Matey, Pilar, Vidya, Raghavan, Sircar, Tapan, Asaad, Oubida, Bhaskar, Pud, Dordea, Matei, Chrysafi, Ada, McCartan, Damian, Dave, Rajiv, Foster, Rachel, Wilson, Rebecca, Okwemba, Sylvia, Majeed, Yousef, Mathen, Vinod, Murphy, John, Barnes, Nicola, Gandhi, Ashu, Harvey, James, Kirwan, Cliona C, Johnson, Richard, Patel, Krupali, Ribas, Maria Dalmau, Vigneswaran, Natali, Challoner, Tom, Park, Alan, Rizkalla, Maged, Tomlins, Abigail, McEvoy, Kat, Jafferbhoy, Sadaf, Soumian, Soni, Narayanan, Sankaran, Kirby, Robert, Bajrusevic, Sladana, Maalo, Joseph, Charalambous, Michalis, Lai, Lee Min, Chong, Kelvin, Thomson, Simon, Monib, Sherif, Chagla, Leena, Audisio, Riccardo, Taghizadeh, Rieka, Iqbal, Azhar, James, Karen, Callaghan, Maria, Poonawala, Shabbir, Lund, Jonathan, Vinayagam, Raman, Thrush, Steven, Thomas, Rachel Bright, Mullan, Michelle, Taylor, Jevan, Yoshimura, Ryo, Mathew, Tom, Jones, Ben Mancey, Munot, Kailas, Nasr, Rana, Piper, Jenny, El-Sharief, Deena, Mustafa, Mohammed, Dumitru, Dorin, Christopoulos, Petros, O'Leary, Peter, Athanasiou, Irene, Johns, Neil, Mehta, Disha, Bibi, Saira, Syed, Farah, Koris, Jacob, Healy, Samuel, Shanks, Lindsay, Oliver, James, Bucata, Claudiu, Clarke, Natalie, Bignell, Kym, Akerlund, Malin, Brock, Lisa, Hallam, Kelly, Howes, Rachel, Armstrong, Alexander, Sethu, Claire, Zeidan, Bashar, Sjokvist, Olivia, Tasoulis, Marios, Sundaramoorthy, Souganthy, Harris, Chad, Wintrip, Dorothy, Lymperopoulos, N, Jain, Yogesh, Balata, Safa Ahmed, Grp, iBRA-2 Steering, and Collab, Breast Reconstruction Res

Subjects
Adult, Cancer Research, medicine.medical_specialty, Time Factors, medicine.medical_treatment, Mammaplasty, trainee collaboratives, Breast Neoplasms, Article, Cohort Studies, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Breast cancer, breast cancer, Adjuvant therapy, cohort study, Medicine, Humans, Prospective Studies, Prospective cohort study, Mastectomy, Aged, Cancer, Aged, 80 and over, Manchester Cancer Research Centre, business.industry, ResearchInstitutes_Networks_Beacons/mcrc, adjuvant therapy, immediate breast reconstruction, Middle Aged, medicine.disease, Surgery, Radiation therapy, Oncology, Centre for Surgical Research, Chemotherapy, Adjuvant, Outcomes research, 030220 oncology & carcinogenesis, Surgical oncology, Female, Breast reconstruction, business, Complication, Cohort study
Abstract

Background: Immediate breast reconstruction (IBR) is routinely offered to improve quality-of-life for women requiring mastectomy, but there are concerns that more complex surgery may delay adjuvant oncological treatments and compromise long-term outcomes. High-quality evidence is lacking. The iBRA-2 study aimed to investigate the impact of IBR on time to adjuvant therapy.Methods: Consecutive women undergoing mastectomy ± IBR for breast cancer July–December, 2016 were included. Patient demographics, operative, oncological and complication data were collected. Time from last definitive cancer surgery to first adjuvant treatment for patients undergoing mastectomy ± IBR were compared and risk factors associated with delays explored.Results: A total of 2540 patients were recruited from 76 centres; 1008 (39.7%) underwent IBR (implant-only [n = 675, 26.6%]; pedicled flaps [n = 105,4.1%] and free-flaps [n = 228, 8.9%]). Complications requiring re-admission or re-operation were significantly more common in patients undergoing IBR than those receiving mastectomy. Adjuvant chemotherapy or radiotherapy was required by 1235 (48.6%) patients. No clinically significant differences were seen in time to adjuvant therapy between patient groups but major complications irrespective of surgery received were significantly associated with treatment delays.Conclusions: IBR does not result in clinically significant delays to adjuvant therapy, but post-operative complications are associated with treatment delays. Strategies to minimise complications, including careful patient selection, are required to improve outcomes for patients.

Published
2019

34. Adjuvant anastrozole versus exemestane versus letrozole, upfront or after 2 years of tamoxifen, in endocrine-sensitive breast cancer (FATA-GIM3): a randomised, phase 3 trial

Author

De Placido, Sabino, primary, Gallo, Ciro, additional, De Laurentiis, Michelino, additional, Bisagni, Giancarlo, additional, Arpino, Grazia, additional, Sarobba, Maria Giuseppa, additional, Riccardi, Ferdinando, additional, Russo, Antonio, additional, Del Mastro, Lucia, additional, Cogoni, Alessio Aligi, additional, Cognetti, Francesco, additional, Gori, Stefania, additional, Foglietta, Jennifer, additional, Frassoldati, Antonio, additional, Amoroso, Domenico, additional, Laudadio, Lucio, additional, Moscetti, Luca, additional, Montemurro, Filippo, additional, Verusio, Claudio, additional, Bernardo, Antonio, additional, Lorusso, Vito, additional, Gravina, Adriano, additional, Moretti, Gabriella, additional, Lauria, Rossella, additional, Lai, Antonella, additional, Mocerino, Carmela, additional, Rizzo, Sergio, additional, Nuzzo, Francesco, additional, Carlini, Paolo, additional, Perrone, Francesco, additional, Accurso, Antonello, additional, Agostara, Biagio, additional, Aieta, Michele, additional, Alabiso, Oscar, additional, Alicicco, Maria Grazia, additional, Amadori, Dino, additional, Amaducci, Laura, additional, Amiconi, Gianna, additional, Antuzzi, Giustino, additional, Ardine, Mara, additional, Ardizzoia, Antonio, additional, Aversa, Caterina, additional, Badalamenti, Giuseppe, additional, Barni, Sandro, additional, Basurto, Carlo, additional, Berardi, Rossana, additional, Bergamasco, Cinzia, additional, Bidoli, Paolo, additional, Bighin, Claudia, additional, Biondi, Edoardo, additional, Boni, Corrado, additional, Borgonovo, Karen, additional, Botta, Mario, additional, Bravi, Stefano, additional, Bruzzi, Paolo, additional, Buono, Giuseppe, additional, Butera, Alfredo, additional, Caldara, Alessia, additional, Candeloro, Giampiero, additional, Cappelletti, Claudia, additional, Cardalesi, Cinzia, additional, Carfora, Elisabetta, additional, Cariello, Anna, additional, Carrozza, Francesco, additional, Cartenì, Giacomo, additional, Caruso, Michele, additional, Casadei, Virginia, additional, Casanova, Claudia, additional, Castori, Luigi, additional, Cavanna, Luigi, additional, Cavazzini, Giovanna, additional, Cazzaniga, Marina, additional, Chilelli, Mario, additional, Chiodini, Paolo, additional, Chiorrini, Silvia, additional, Ciardiello, Fortunato, additional, Ciccarese, Mariangela, additional, Cinieri, Saverio, additional, Clerico, Mario, additional, Coccaro, Mariarosa, additional, Comande, Mario, additional, Corbo, Claudia, additional, Cortino, Giuseppina, additional, Cusenza, Stefania, additional, Daniele, Gennaro, additional, D'arco, Alfonso Maria, additional, D'auria, Giuliana, additional, Dazzi, Claudio, additional, De Angelis, Carmine, additional, de Braud, Filippo, additional, De Feo, Gianfranco, additional, De Matteis, Andrea, additional, De Tursi, Michele, additional, Di Blasio, Anna, additional, di Lucca, Giuseppe, additional, Di Lullo, Liberato, additional, Di Rella, Francesca, additional, Di Renzo, Gianfranco, additional, Di Stefano, Pia, additional, Di Stefano, Aida, additional, Diana, Anna, additional, Donati, Sara, additional, Fabbri, Agnese, additional, Fabi, Alessandra, additional, Faedi, Marina, additional, Farina, Gabriella, additional, Farris, Antonio, additional, Febbraro, Antonio, additional, Fedele, Palma, additional, Federico, Piera, additional, Ferraù, Francesco, additional, Ferretti, Gianluigi, additional, Ferro, Antonella, additional, Floriani, Irene, additional, Forcignanò, Rosachiara, additional, Forciniti, Samantha, additional, Forestieri, Valeria, additional, Fornari, Gianni, additional, Frisinghelli, Michela, additional, Fusco, Vittorio, additional, Gallizzi, Giulia, additional, Galvano, Antonio, additional, Gambardella, Antonio, additional, Gambi, Angelo, additional, Gebbia, Vittorio, additional, Gervasi, Erika, additional, Ghilardi, Mara, additional, Giacobino, Alice, additional, Giardina, Giovanni, additional, Giotta, Francesco, additional, Giraudi, Sara, additional, Giuliano, Mario, additional, Grassadonia, Antonino, additional, Grasso, Donatella, additional, Grosso, Federica, additional, Guizzaro, Lorenzo, additional, Incoronato, Pasquale, additional, Incorvaia, Lorena, additional, Iodice, Giovanni, additional, La Verde, Nicla, additional, Labonia, Vincenzo, additional, Landi, Gabriella, additional, Latorre, Agnese, additional, Leonardi, Vita, additional, Levaggi, Alessia, additional, Limite, Gennaro, additional, Lina Bascialla, Linda, additional, Livi, Lorenzo, additional, Maiello, Evaristo, additional, Mandelli, Daniela, additional, Marcon, Ilaria, additional, Menon, Daniela, additional, Montedoro, Michele, additional, Moraca, Lucia, additional, Moretti, Anna, additional, Morritti, Maria Grazia, additional, Morselli, Patrizia, additional, Mura, Antonella, additional, Mura, Silvia, additional, Musacchio, Michela, additional, Muzio, Alberto, additional, Natale, Donato, additional, Natoli, Clara, additional, Nigro, Cinzia, additional, Nisticò, Cecilia, additional, Nuzzo, Antonio, additional, Orditura, Michele, additional, Orlando, Laura, additional, Pacilio, Carmen, additional, Palumbo, Giuliano, additional, Palumbo, Raffaella, additional, Pasini, Felice, additional, Paterno, Emanuela, additional, Pazzola, Antonio, additional, Pelliccioni, Silvia, additional, Pensabene, Matilde, additional, Perroni, Davide, additional, Pesenti Gritti, Angela, additional, Petrelli, Fausto, additional, Piccirillo, Maria Carmela, additional, Pinotti, Graziella, additional, Pogliani, Claudia, additional, Poli, Davide, additional, Prader, Sonia, additional, Recchia, Francesco, additional, Rizzi, Daniele, additional, Romano, Carmen, additional, Rossello, Rosalba, additional, Rossini, Chiara, additional, Salvucci, Giuseppina, additional, Sanna, Valeria, additional, Santini, Alessandra, additional, Saracchini, Silvana, additional, Savastano, Clementina, additional, Scambia, Giovanni, additional, Schettini, Francesco, additional, Schiavone, Paola, additional, Schirone, Alessio, additional, Seles, Elena, additional, Signoriello, Simona, additional, Signoriello, Giuseppe, additional, Silva, Rosa Rita, additional, Silvestri, Antonia, additional, Simeon, Vittorio, additional, Spagnoletti, Ilaria, additional, Tamberi, Stefano, additional, Teragni, Cristina, additional, Thalmann, Verena, additional, Thomas, Renato, additional, Thomas, Guglielmo, additional, Tienghi, Amelia, additional, Tinari, Nicola, additional, Tinessa, Vincenza, additional, Tomei, Federica, additional, Tonini, Giuseppe, additional, Torri, Valter, additional, Traficante, Divina, additional, Tudini, Marianna, additional, Turazza, Monica, additional, Vignoli, Roberto, additional, Vitale, Maria Giuseppa, additional, Zacchia, Alessandra, additional, Zagarese, Pasquale, additional, Zanni, Alda, additional, Zavallone, Laura, additional, Zavettieri, Maria, additional, and Zoboli, Alessandra, additional

Published
2018
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35. Combined effect of obesity and diabetes on early breast cancer outcome: a prospective observational study

Author

Buono, Giuseppe, primary, Crispo, Anna, additional, Giuliano, Mario, additional, De Angelis, Carmine, additional, Schettini, Francesco, additional, Forestieri, Valeria, additional, Lauria, Rossella, additional, Pensabene, Matilde, additional, De Laurentiis, Michelino, additional, Augustin, Livia Silvia Adriana, additional, Amore, Alfonso, additional, D’Aiuto, Massimiliano, additional, Tortoriello, Raffaele, additional, Accurso, Antonello, additional, Cavalcanti, Ernesta, additional, Botti, Gerardo, additional, Montella, Maurizio, additional, De Placido, Sabino, additional, and Arpino, Grazia, additional

Published
2017
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37. Undertreatment of breast cancer in the elderly

Author

Rocco, Nicola, Rispoli, Corrado, Pagano, Gennaro, Ascione, Silvio, Compagna, Rita, Danzi, Michele, Accurso, Antonello, Amato, Bruno, Nicola, Rocco, Corrado, Rispoli, Gennaro, Pagano, Silvio, Ascione, Compagna, Rita, Danzi, Michele, Accurso, Antonello, and Bruno, Amato

Subjects
Adult, Aged, 80 and over, Young Adult, Retraction Note, Humans, Surgery, Breast Neoplasms, Female, Therapeutics, Middle Aged, Research Article, Aged
Abstract

Aims The effect of undertreatment with adjuvant hormonal therapy, chemotherapy or radiation was studied in elderly women with breast cancer. Methods A prospectively maintained database was used to identify women undergoing potentially curative surgery between 1997 and 2011. The presentation, pathologic findings, treatment and outcomes of 449 women over 65 were compared to the findings in 1049 younger patients. Moreover, conventionally treated and undertreated elderly patients were identified and their characteristics and outcomes were compared. Results Both young and old patients presented most frequently with mammographic findings, but older patients presented more frequently with mammographic masses while younger patients presented more frequently with mammographic calcifications. Cancers of older patients were signicantly more favorable than cancers in younger patients with more infiltrating lobular, fewer ductal carcinoma in situ and more frequently estrogen receptor positive and fewer were poorly differentiated. Elderly patients had less axillary surgery, less adjuvant radiation therapy and more hormonal therapy. Fourty-six percent of the 449 elderly patients were undertreated by conventional criteria. Undertreated patients were more frequently in situ, better differentiated, smaller, and more often estrogen receptor positive. Forty-four percent of the undertreated patients died during follow-up without disease recurrence. Conclusions Despite undertreatment, local and distant disease-free survival was comparable to patients who were not undertreated.

Published
2013

39. Myofibroblastoma of the breast: report of a case with radiological, cytological and histological findings

Author

COZZOLINO, IMMACOLATA, VARONE, VALERIA, CIANCIA, GIUSEPPE, ACCURSO, ANTONELLO, PETTINATO, GUIDO, VETRANI, ANTONIO, SIAPEC, Cozzolino, Immacolata, Varone, Valeria, Ciancia, Giuseppe, Accurso, Antonello, Pettinato, Guido, and Vetrani, Antonio

Abstract

Background. Myofibroblastoma of the breast is an uncommon benign mesenchymal neoplasm that occurs predominantly in elderly men. Methods. A 64-years-old woman presented a slowly growing lump in her left breast. A mammogram revealed a 15 mm radiopaque lesion with regular margins and no microcalcifications and ultrasonography showed well-circumscribed, oval, hypoechoic mass measuring 28 mm, in the upper outer quadrant of the left breast. A US-Guided Fine Needle Aspiration Cytology (US-FNAC) was performed, showing tumour cells arranged in cohesive groups or in fascicular clusters and, in the background, naked nuclei. The cells were spindle shaped with a scanty amount of cytoplasm, oval nuclei with finely granular chromatin and occasional inconspicuous nucleoli. Fragments of stromal collagen were observed. The lesion was diagnosed as a mesenchymal proliferation without atypia and surgical biopsy was recommended. The patient underwent a surgical excision biopsy and histologic examination showed a 2.8 x 2.1 cm nodular mass, well- circumscribed although not truly capsulated, firm, rubbery, with a whirling appearance and a greyish external surface on cut sections. The slides showed a well-defined hyalinised tumour with a spindle cell proliferation and abundant dense fibrous collagen; the lesion was circumscribed by a thin “pseudocapsule” of compress glandular stroma. The spindle cells were arranged in short and haphazardly intersecting fascicles and clusters and were mixed with broad bands of brightly eosinophilic hyalinised collagen. Individual cells were bland-looking and showed a single ovoid nucleus with, occasionally, one or two nucleoli. Mitotic figures were uncommon and cytological atypia was not observed. Mast cells were conspicuous. The spindle cells stain positively for vimentin, CD34, desmin, H-caldesmon, CD99, bcl2. Results. The morphologic features, in conjunction with the immunophenotype, were consistent with a myofibroblastoma of the breast (classic type).

Published
2013

40. Different types of implants for reconstructive breast surgery

Author

Rocco, Nicola, primary, Rispoli, Corrado, additional, Moja, Lorenzo, additional, Amato, Bruno, additional, Iannone, Loredana, additional, Testa, Serena, additional, Spano, Andrea, additional, Catanuto, Giuseppe, additional, Accurso, Antonello, additional, and Nava, Maurizio B, additional

Published
2016
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42. A rare case of true carcinosarcoma of the breast

Author

Accurso, Antonello, primary, Ciancia, Giuseppe, additional, Della Corte, Gianni Antonio, additional, Reale, Paola, additional, Accardo, Giuseppe, additional, Salerno, Carmela, additional, Bordoni, Daniele, additional, Falco, Giuseppe, additional, and Rocco, Nicola, additional

Published
2016
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43. Primary angiosarcoma of the breast

Author

Bordoni, Daniele, primary, Bolletta, Elisa, additional, Falco, Giuseppe, additional, Cadenelli, Pierfrancesco, additional, Rocco, Nicola, additional, Tessone, Ariel, additional, Guarino, Stefania, additional, Accurso, Antonello, additional, Amato, Bruno, additional, and Magalotti, Cesare, additional

Published
2016
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44. Adjuvant therapy and outcomes in patients with stage IA breast cancer.

Author

Arpino, Grazia, primary, Giuliano, Mario, additional, De Angelis, Carmine, additional, Di Maio, Massimo, additional, Schettini, Francesco, additional, Von Arx, Claudia, additional, Riccardi, Ferdinando, additional, Palumbo, Giuliano, additional, De Laurentiis, Michelino, additional, Crispo, Anna, additional, Montella, Maurizio, additional, Grimaldi, Maria, additional, Trunfio, Martino, additional, Limite, Gennaro, additional, Accurso, Antonello, additional, and De Placido, Sabino, additional

Published
2015
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45. Confocal laser endomicroscopy in breast surgery: a pilot study

Author

De Palma, Giovanni D, primary, Esposito, Dario, additional, Luglio, Gaetano, additional, Limite, Gennaro, additional, Accurso, Antonello, additional, Sollazzo, Viviana, additional, Maione, Francesco, additional, Cassese, Gianluca, additional, Siciliano, Saverio, additional, Gennarelli, Nicola, additional, Ilardi, Gennaro, additional, Paternoster, Mariano, additional, Giglio, Mariano C, additional, and Forestieri, Pietro, additional

Published
2015
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48. Different types of implants for reconstructive breast surgery

Author

Rocco, Nicola, primary, Rispoli, Corrado, additional, Moja, Lorenzo, additional, Amato, Bruno, additional, Iannone, Loredana, additional, Testa, Serena, additional, Spano, Andrea, additional, Catanuto, Giuseppe, additional, Accurso, Antonello, additional, and Nava, Maurizio Bruno, additional

Published
2014
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