141 results on '"Acarturk, C"'
Search Results
2. The psychological impacts of COVID-19 related stressors on Syrian refugees in Turkey: The role of resource loss, discrimination, and social support
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Kurt, G., Ilkkursun, Z., Javanbakht, A., Uygun, E., Karaoglan-Kahilogullari, A., and Acarturk, C.
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- 2021
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3. Somatic distress among Syrian refugees in Istanbul, Turkey: A cross-sectional study
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McGrath, M., Acarturk, C., Roberts, B., Ilkkursun, Z., Sondorp, E., Sijbrandij, M., Cuijpers, P., Ventevogel, P., McKee, M., and Fuhr, D.C.
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- 2020
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4. Health system responsiveness to the mental health needs of Syrian refugees: mixed-methods rapid appraisals in eight host countries in Europe and the Middle East.
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Woodward, A, Fuhr, DC, Barry, AS, Balabanova, D, Sondorp, E, Dieleman, MA, Pratley, P, Schoenberger, SF, McKee, M, Ilkkursun, Z, Acarturk, C, Burchert, S, Knaevelsrud, C, Brown, FL, Steen, F, Spaaij, J, Morina, N, de Graaff, AM, Sijbrandij, M, Cuijpers, P, Bryant, R, Akhtar, A, Roberts, B, STRENGTHS consortium, Woodward, A, Fuhr, DC, Barry, AS, Balabanova, D, Sondorp, E, Dieleman, MA, Pratley, P, Schoenberger, SF, McKee, M, Ilkkursun, Z, Acarturk, C, Burchert, S, Knaevelsrud, C, Brown, FL, Steen, F, Spaaij, J, Morina, N, de Graaff, AM, Sijbrandij, M, Cuijpers, P, Bryant, R, Akhtar, A, Roberts, B, and STRENGTHS consortium
- Abstract
BACKGROUND: Syrian refugees have a high burden of mental health symptoms and face challenges in accessing mental health and psychosocial support (MHPSS). This study assesses health system responsiveness (HSR) to the MHPSS needs of Syrian refugees, comparing countries in Europe and the Middle East to inform recommendations for strengthening MHPSS systems. METHODS: A mixed-methods rapid appraisal methodology guided by an adapted WHO Health System Framework was used to assess HSR in eight countries (Egypt, Germany, Jordan, Lebanon, Netherlands, Sweden, Switzerland, and Türkiye). Quantitative and qualitative analysis of primary and secondary data was used. Data collection and analysis were performed iteratively by multiple researchers. Country reports were used for comparative analysis and synthesis. RESULTS: We found numerous constraints in HSR: i) Too few appropriate mental health providers and services; ii) Travel-related barriers impeding access to services, widening rural-urban inequalities in the distribution of mental health workers; iii) Cultural, language, and knowledge-related barriers to timely care likely caused by insufficient numbers of culturally sensitive providers, costs of professional interpreters, somatic presentations of distress by Syrian refugees, limited mental health awareness, and stigma associated to mental illness; iv) High out-of-pocket costs for psychological treatment and transportation to services reducing affordability, particularly in middle-income countries; v) Long waiting times for specialist mental health services; vi) Information gaps on the mental health needs of refugees and responsiveness of MHPSS systems in all countries. Six recommendations are provided to address these issues. CONCLUSIONS: All eight host countries struggle to provide responsive MHPSS to Syrian refugees. Strengthening the mental health workforce (in terms of quantity, quality, diversity, and distribution) is urgently needed to enable Syrian refugees to receive
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- 2023
5. Have the COVID-19 outbreak and related restrictions affected the right to mental health of people with severe mental health conditions?
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Nosè, M., primary, Gastaldon, C., additional, Acarturk, C, additional, Purgato, M., additional, Ostuzzi, G., additional, and Barbui, C, additional
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- 2022
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6. Group problem management plus (PM+) to decrease psychological distress among Syrian refugees in Turkey: a pilot randomised controlled trial.
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Acarturk, C, Uygun, E, Ilkkursun, Z, Yurtbakan, T, Kurt, G, Adam-Troian, J, Senay, I, Bryant, R, Cuijpers, P, Kiselev, N, McDaid, D, Morina, N, Nisanci, Z, Park, AL, Sijbrandij, M, Ventevogel, P, Fuhr, DC, Acarturk, C, Uygun, E, Ilkkursun, Z, Yurtbakan, T, Kurt, G, Adam-Troian, J, Senay, I, Bryant, R, Cuijpers, P, Kiselev, N, McDaid, D, Morina, N, Nisanci, Z, Park, AL, Sijbrandij, M, Ventevogel, P, and Fuhr, DC
- Abstract
BACKGROUND: Syrian refugees resettled in Turkey show a high prevalence of symptoms of mental disorders. Problem Management Plus (PM+) is an effective psychological intervention delivered by non-specialist health care providers which has shown to decrease psychological distress among people exposed to adversity. In this single-blind pilot randomised controlled trial, we examined the methodological trial procedures of Group PM+ (gPM+) among Syrian refugees with psychological distress in Istanbul, Turkey, and assessed feasibility, acceptability, perceived impact and the potential cost-effectiveness of the intervention. METHODS: Refugees with psychological distress (Kessler Psychological Distress Scale, K10 > 15) and impaired psychosocial functioning (World Health Organization Disability Assessment Schedule, WHODAS 2.0 > 16) were recruited from the community and randomised to either gPM+ and enhanced care as usual (E-CAU) (n = 24) or E-CAU only (n = 22). gPM+ comprised of five weekly group sessions with eight to ten participants per group. Acceptability and feasibility of the intervention were assessed through semi-structured interviews. The primary outcome at 3-month follow-up was symptoms of depression and anxiety (Hopkins Symptoms Checklist-25). Psychosocial functioning (WHODAS 2.0), symptoms of posttraumatic stress disorder and self-identified problems (Psychological Outcomes Profiles, PSYCHLOPS) were included as secondary outcomes. A modified version of the Client Service Receipt Inventory was used to document changes in the costs of health service utilisation as well as productivity losses. RESULTS: There were no barriers experienced in recruiting study participants and in randomising them into the respective study arms. Retention in gPM+ was high (75%). Qualitative analyses of the interviews with the participants showed that Syrian refugees had a positive view on the content, implementation and format of gPM+. No adverse events were reported during the implementa
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- 2022
7. Scalable psychological interventions for Syrian refugees in Europe and the Middle East: STRENGTHS study protocol for a prospective individual participant data meta-analysis
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de Graaff, AM, Cuijpers, P, Acarturk, C, Akhtar, A, Alkneme, MS, Aoun, M, Awwad, M, Bawaneh, AY, Brown, FL, Bryant, R, Burchert, S, Carswell, K, Drogendijk, A, Engels, M, Fuhr, DC, Hansen, P, van't Hof, E, Giardinelli, L, Hemmo, M, Hessling, JM, Ilkkursun, Z, Jordans, MJD, Kiselev, N, Knaevelsrud, C, Kurt, G, Martinmaki, S, McDaid, D, Morina, N, Naser, H, Park, A-L, Pfaltz, MC, Roberts, B, Schick, M, Schnyder, U, Spaaij, J, Steen, F, Taha, K, Uygun, E, Ventevogel, P, Whitney, C, Witteveen, AB, Sijbrandij, M, de Graaff, AM, Cuijpers, P, Acarturk, C, Akhtar, A, Alkneme, MS, Aoun, M, Awwad, M, Bawaneh, AY, Brown, FL, Bryant, R, Burchert, S, Carswell, K, Drogendijk, A, Engels, M, Fuhr, DC, Hansen, P, van't Hof, E, Giardinelli, L, Hemmo, M, Hessling, JM, Ilkkursun, Z, Jordans, MJD, Kiselev, N, Knaevelsrud, C, Kurt, G, Martinmaki, S, McDaid, D, Morina, N, Naser, H, Park, A-L, Pfaltz, MC, Roberts, B, Schick, M, Schnyder, U, Spaaij, J, Steen, F, Taha, K, Uygun, E, Ventevogel, P, Whitney, C, Witteveen, AB, and Sijbrandij, M
- Abstract
INTRODUCTION: The World Health Organization's (WHO) scalable psychological interventions, such as Problem Management Plus (PM+) and Step-by-Step (SbS) are designed to be cost-effective non-specialist delivered interventions to reduce symptoms of common mental disorders, such as anxiety, depression and post-traumatic stress disorder (PTSD). The STRENGTHS consortium aims to evaluate the effectiveness, cost-effectiveness and implementation of the individual format of PM+ and its group version (gPM+), as well as of the digital SbS intervention among Syrian refugees in seven countries in Europe and the Middle East. This is a study protocol for a prospective individual participant data (IPD) meta-analysis to evaluate (1) overall effectiveness and cost-effectiveness and (2) treatment moderators of PM+, gPM+ and SbS with Syrian refugees. METHODS AND ANALYSIS: Five pilot randomised controlled trials (RCTs) and seven fully powered RCTs conducted within STRENGTHS will be combined into one IPD meta-analytic dataset. The RCTs include Syrian refugees of 18 years and above with elevated psychological distress (Kessler Psychological Distress Scale (K10>15)) and impaired daily functioning (WHO Disability Assessment Schedule 2.0 (WHODAS 2.0>16)). Participants are randomised into the intervention or care as usual control group, and complete follow-up assessments at 1-week, 3-month and 12-month follow-up. Primary outcomes are symptoms of depression and anxiety (25-item Hopkins Symptom Checklist). Secondary outcomes include daily functioning (WHODAS 2.0), PTSD symptoms (PTSD Checklist for DSM-5) and self-identified problems (PSYCHLOPS). We will conduct a one-stage IPD meta-analysis using linear mixed models. Quality of evidence will be assessed using the GRADE approach, and the economic evaluation approach will be assessed using the CHEC-list. ETHICS AND DISSEMINATION: Local ethical approval has been obtained for each RCT. This IPD meta-analysis does not require ethical approval. The re
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- 2022
8. Resilience of people with chronic medical conditions during the COVID-19 pandemic: a 1-year longitudinal prospective survey.
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Tarsitani, L, Pinucci, I, Tedeschi, F, Patanè, M, Papola, D, Palantza, C, Acarturk, C, Björkenstam, E, Bryant, R, Burchert, S, Davisse-Paturet, C, Díaz-García, A, Farrel, R, Fuhr, DC, Hall, BJ, Huizink, AC, Lam, AIF, Kurt, G, Leijen, I, Mittendorfer-Rutz, E, Morina, N, Panter-Brick, C, Purba, FD, Quero, S, Seedat, S, Setyowibowo, H, van der Waerden, J, Pasquini, M, Sijbrandij, M, Barbui, C, Tarsitani, L, Pinucci, I, Tedeschi, F, Patanè, M, Papola, D, Palantza, C, Acarturk, C, Björkenstam, E, Bryant, R, Burchert, S, Davisse-Paturet, C, Díaz-García, A, Farrel, R, Fuhr, DC, Hall, BJ, Huizink, AC, Lam, AIF, Kurt, G, Leijen, I, Mittendorfer-Rutz, E, Morina, N, Panter-Brick, C, Purba, FD, Quero, S, Seedat, S, Setyowibowo, H, van der Waerden, J, Pasquini, M, Sijbrandij, M, and Barbui, C
- Abstract
BACKGROUNDS: Individuals with chronic medical conditions are considered highly exposed to COVID-19 pandemic stress, but emerging evidence is demonstrating that resilience is common even among them. We aimed at identifying sustained resilient outcomes and their predictors in chronically ill people during the first year of the pandemic. METHODS: This international 4-wave 1-year longitudinal online survey included items on socio-demographic characteristics, economic and living situation, lifestyle and habits, pandemic-related issues, and history of mental disorders. Adherence to and approval of imposed restrictions, trust in governments and in scientific community during the pandemic were also investigated. The following tools were administered: the Patient Health Questionnaire, the Generalized Anxiety Disorder scale, the PTSD Checklist DSM-5, the Oslo Social Support Scale, the Padua Inventory, and the Portrait Values Questionnaire. RESULTS: One thousand fifty-two individuals reporting a chronic condition out of 8011 total participants from 13 countries were included in the study, and 965 had data available for the final model. The estimated probability of being "sustained-resilient" was 34%. Older male individuals, participants employed before and during the pandemic or with perceived social support were more likely to belong to the sustained-resilience group. Loneliness, a previous mental disorder, high hedonism, fear of COVID-19 contamination, concern for the health of loved ones, and non-approving pandemic restrictions were predictors of not-resilient outcomes in our sample. CONCLUSIONS: We found similarities and differences from established predictors of resilience and identified some new ones specific to pandemics. Further investigation is warranted and could inform the design of resilience-building interventions in people with chronic diseases.
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- 2022
9. Effectiveness of a WHO self-help psychological intervention for preventing mental disorders among Syrian refugees in Turkey: a randomized controlled trial
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Acarturk, C, Uygun, E, Ilkkursun, Z, Carswell, K, Tedeschi, F, Batu, M, Eskici, S, Kurt, G, Anttila, M, Au, T, Baumgartner, J, Churchill, R, Cuijpers, P, Becker, T, Koesters, M, Lantta, T, Nosè, M, Ostuzzi, G, Popa, M, Purgato, M, Sijbrandij, M, Turrini, G, Välimäki, M, Walker, L, Wancata, J, Zanini, E, White, RG, van Ommeren, M, Barbui, C, Acarturk, C, Uygun, E, Ilkkursun, Z, Carswell, K, Tedeschi, F, Batu, M, Eskici, S, Kurt, G, Anttila, M, Au, T, Baumgartner, J, Churchill, R, Cuijpers, P, Becker, T, Koesters, M, Lantta, T, Nosè, M, Ostuzzi, G, Popa, M, Purgato, M, Sijbrandij, M, Turrini, G, Välimäki, M, Walker, L, Wancata, J, Zanini, E, White, RG, van Ommeren, M, and Barbui, C
- Abstract
Refugees are at high risk of developing mental disorders. There is no evidence from randomized controlled trials (RCTs) that psychological interventions can prevent the onset of mental disorders in this group. We assessed the effectiveness of a self-help psychological intervention developed by the World Health Organization, called Self-Help Plus, in preventing the development of mental disorders among Syrian refugees experiencing psychological distress in Turkey. A two-arm, assessor-masked RCT was conducted in two Turkish areas. Eligible participants were adult Syrian refugees experiencing psychological distress (General Health Questionnaire ≥3), but without a diagnosis of mental disorder. They were randomly assigned either to the Self-Help Plus arm (consisting of Self-Help Plus combined with Enhanced Care as Usual, ECAU) or to ECAU only in a 1:1 ratio. Self-Help Plus was delivered in a group format by two facilitators over five sessions. The primary outcome measure was the presence of any mental disorder assessed by the Mini International Neuropsychiatric Interview at six-month follow-up. Secondary outcome measures were the presence of mental disorders at post-intervention, and psychological distress, symptoms of post-traumatic stress disorder and depression, personally identified psychological outcomes, functional impairment, subjective well-being, and quality of life at post-intervention and six-month follow-up. Between October 1, 2018 and November 30, 2019, 1,186 refugees were assessed for inclusion. Five hundred forty-four people were ineligible, and 642 participants were enrolled and randomly assigned to either Self-Help Plus (N=322) or ECAU (N=320). Self-Help Plus participants were significantly less likely to have any mental disorders at six-month follow-up compared to the ECAU group (21.69% vs. 40.73%; Cramer's V = 0.205, p<0.001, risk ratio: 0.533, 95% CI: 0.408-0.696). Analysis of secondary outcomes suggested that Self-Help Plus was not effective immediat
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- 2022
10. Additional file 1 of Group problem management plus (PM+) to decrease psychological distress among Syrian refugees in Turkey: a pilot randomised controlled trial
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Acarturk, C., Uygun, E., Ilkkursun, Z., Yurtbakan, T., Kurt, G., Adam-Troian, J., Senay, I., Bryant, R., Cuijpers, P., Kiselev, N., McDaid, D., Morina, N., Nisanci, Z., Park, A. L., Sijbrandij, M., Ventevogel, P., and Fuhr, D. C.
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Data_FILES - Abstract
Additional file 1.
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- 2022
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11. Adverse childhood experiences and global mental health: avenues to reduce the burden of child and adolescent mental disorders
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Ceccarelli, C., primary, Prina, E., additional, Muneghina, O., additional, Jordans, M., additional, Barker, E., additional, Miller, K., additional, Singh, R., additional, Acarturk, C., additional, Sorsdhal, K., additional, Cuijpers, P., additional, Lund, C., additional, Barbui, C., additional, and Purgato, M., additional
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- 2022
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12. Adverse childhood experiences and global mental health: avenues to reduce the burden of child and adolescent mental disorders – CORRIGENDUM
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Ceccar, C., primary, Prina, E., additional, Muneghina, O., additional, Jordans, M., additional, Barker, E., additional, Miller, K., additional, Singh, R., additional, Acarturk, C., additional, Sorsdhal, K., additional, Cuijpers, P., additional, Lund, C., additional, Barbui, C., additional, and Purgato, M., additional
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- 2022
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13. Economic costs of social phobia: A population-based study
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Acarturk, C., Smit, Filip, de Graaf, R., van Straten, A., ten Have, M., and Cuijpers, P.
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- 2009
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14. Have the COVID-19 outbreak and related restrictions affected the right to mental health of people with severe mental health conditions?
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Nosè, M., Gastaldon, C., Acarturk, C, Purgato, M., Ostuzzi, G., and Barbui, C
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ONLINE information services ,PSYCHOLOGY information storage & retrieval systems ,SYSTEMATIC reviews ,SCHIZOPHRENIA ,MENTAL health ,SOCIAL isolation ,MENTAL depression ,LONELINESS ,MEDLINE ,ANXIETY ,INSOMNIA ,COVID-19 pandemic ,BIPOLAR disorder ,PSYCHOLOGICAL stress ,PSYCHOLOGICAL distress - Abstract
The Coronavirus disease (COVID-19) outbreak, and the restrictions implemented by governments to limit its public health impact, may have determined a reduction of the right to mental health of people with severe mental health conditions, that is a limitation to adequate, human, and value-based mental healthcare, with rising inequalities in comparison with the general population. This systematic review was, therefore, conducted to collate evidence on the impact of the pandemic period on the mental health of individuals with pre-existing severe mental health conditions. Of 3,774 retrieved citations, we selected 21 studies meeting the inclusion criteria. The majority of the included studies assessed trends in psychological symptoms over the pandemic period, then arguing that symptoms worsened for a number of reasons, including the risk of contracting the virus, the disruption of mental health services, and the feelings of loneliness and isolation associated with the restriction measures. Even though studies provided somewhat contradictory results, the majority of evidence indicates that people with pre-existing mental health conditions were more likely to report greater self-isolation distress, anxiety, depression, COVID-19-related perceived stress, and were more likely to voluntarily self-isolate than those without a mental health condition. These findings appeared to suggest that a combination of factors related to the pandemic itself and to the prevention and mitigation strategies were responsible for a reduction of the right to mental health of people with mental health conditions, with increased inequalities in comparison with the general population. [ABSTRACT FROM AUTHOR]
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- 2023
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15. Self-help plus for refugees and asylum seekers; study protocol for a series of individual participant data meta-analyses 难民和寻求庇护者自助服务: 一系列个人参与者数据元分析的研究方案 Self-Help Plus para Refugiados y solicitantes de asilo; Protocolo de Estudio para una serie de Meta-análisis de datos de participantes individuales
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Karyotaki, E., Sijbrandij, M., Purgato, M., Acarturk, C., Lakin, D., Bailey, D., Peckham, E., Uygun, E., Tedeschi, F., Wancata, J., Augustinavicius, J., Carswell, K., Välimäki, M., van Ommeren, M., Koesters, M., Popa, M., Leku, M.R., Anttila, M., Churchill, R., White, R., Al-Hashimi, S., Lantta, T., Au, T., Klein, T., Tol, W.A., Cuijpers, P., Barbui, C., Clinical Psychology, World Health Organization (WHO) Collaborating Center, APH - Mental Health, and APH - Global Health
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SDG 10 - Reduced Inequalities - Abstract
© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.Background: Refugees and asylum seekers face various stressors due to displacement and are especially vulnerable to common mental disorders. To effectively manage psychological distress in this population, innovative interventions are required. The World Health Organization (WHO) Self-Help Plus (SH+) intervention has shown promising outcomes in reducing symptoms of common mental disorders among refugees and asylum seekers. However, individual participant differences in response to SH+ remain largely unknown. The Individual Participant Data (IPD) meta-analysis synthesizes raw datasets of trials to provide cutting-edge evidence of outcomes that cannot be examined by conventional meta-analytic approaches. Objectives: This protocol outlines the methods of a series of IPD meta-analyses aimed at examining the effects and potential moderators of SH+ in (a) reducing depressive symptoms at post-intervention and (b) preventing the six-month cumulative incidence of mental disorders in refugees and asylum seekers. Method: RCTs on SH+ have been identified through WHO and all authors have agreed to share the datasets of the trials. The primary outcomes of the IPD meta-analyses are (a) reduction in depressive symptoms at post-intervention, and (b) prevention of six-month cumulative incidence of mental disorders. Secondary outcomes include post-traumatic stress disorder symptoms, well-being, functioning, quality of life, and twelve-month cumulative incidence of mental disorders. One-stage IPD meta-analyses will be performed using mixed-effects linear/logistic regression. Missing data will be handled by multiple imputation. Conclusions: These results will enrich current knowledge about the response to SH+ and will facilitate its targeted dissemination. The results of these IPD meta-analyses will be published in peer-reviewed journals.
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- 2021
16. Social phobia and number of social fears, and their association with comorbidity, health-related quality of life and help seeking: A population-based study
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Acarturk, C., de Graaf, Ron, van Straten, A., Have, M. ten, and Cuijpers, P.
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- 2008
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17. Problems after flight: understanding and comparing Syrians' perspectives in the Middle East and Europe.
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Drescher, A, Kiselev, N, Akhtar, A, Acarturk, C, Bryant, RA, Ilkkursun, Z, von Känel, R, Miller, KE, Pfaltz, MC, Schick, M, Schnyder, U, Sijbrandij, M, Spaaij, J, Morina, N, Drescher, A, Kiselev, N, Akhtar, A, Acarturk, C, Bryant, RA, Ilkkursun, Z, von Känel, R, Miller, KE, Pfaltz, MC, Schick, M, Schnyder, U, Sijbrandij, M, Spaaij, J, and Morina, N
- Abstract
BACKGROUND: Syrian refugees and asylum seekers (SRAs) face multiple stressors after flight, which may vary due to different geographic, economic, cultural and socio-political contexts in the host countries. Past research has recognised the importance of participants' own perspectives. The aims of this multi-country study were to identify and compare self-reported problems of SRAs between various settings. METHODS: A semi-structured client-generated outcome measurement was used to collect data among adult SRAs in Jordan (N = 61), Turkey (N = 46) and Switzerland (N = 57) between September 2018 and November 2019. Answers were analysed following thematic analysis. RESULTS: Over half of the participants reported practical problems with an emphasis on camp-related problems (Jordan), finances (Turkey), employment (Jordan and Switzerland) and government regulations (Switzerland), followed by psychological, and social issues. CONCLUSION: This study highlights the impact of local contextual factors on wellbeing. The findings emphasise that planning preventative procedures and mental health care services for SRAs need to consider local challenges affecting the population in specific countries.
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- 2021
18. Problems after flight : understanding and comparing Syrians' perspectives in the Middle East and Europe
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Drescher, A., Kiselev, N., Akhtar, A., Acarturk, C., Bryant, R. A., Ilkkursun, Z., von Känel, R., Miller, K. E., Pfaltz, Monique C., Schick, M., Schnyder, U., Sijbrandij, M., Spaaij, J., Morina, N., Drescher, A., Kiselev, N., Akhtar, A., Acarturk, C., Bryant, R. A., Ilkkursun, Z., von Känel, R., Miller, K. E., Pfaltz, Monique C., Schick, M., Schnyder, U., Sijbrandij, M., Spaaij, J., and Morina, N.
- Abstract
Background: Syrian refugees and asylum seekers (SRAs) face multiple stressors after flight, which may vary due to different geographic, economic, cultural and socio-political contexts in the host countries. Past research has recognised the importance of participantsâ own perspectives. The aims of this multi-country study were to identify and compare self-reported problems of SRAs between various settings. Methods: A semi-structured client-generated outcome measurement was used to collect data among adult SRAs in Jordan (N = 61), Turkey (N = 46) and Switzerland (N = 57) between September 2018 and November 2019. Answers were analysed following thematic analysis. Results: Over half of the participants reported practical problems with an emphasis on camp-related problems (Jordan), finances (Turkey), employment (Jordan and Switzerland) and government regulations (Switzerland), followed by psychological, and social issues. Conclusion: This study highlights the impact of local contextual factors on wellbeing. The findings emphasise that planning preventative procedures and mental health care services for SRAs need to consider local challenges affecting the population in specific countries. © 2021, The Author(s).
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- 2021
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19. Group problem management plus for decreasing psychological distress in Syrian refugees in Turkey
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Acarturk, C, primary, İlkkurşun, Z, additional, Yurtbakan, T, additional, Troian, J, additional, and Uygun, E, additional
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- 2020
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20. Psychological treatment of social anxiety disorder: a meta-analysis
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Acarturk, C., Cuijpers, P., van Straten, A., and de Graaf, R.
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- 2009
21. Incidence of social phobia and identification of its risk indicators: a model for prevention
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Acarturk, C., Smit, F., de Graaf, R., van Straten, A., ten Have, M., and Cuijpers, P.
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- 2009
22. Effectiveness of a peer-refugee delivered psychological intervention to reduce psychological distress among adult Syrian refugees in the Netherlands: study protocol
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de Graaff, AM, Cuijpers, P, Acarturk, C, Bryant, R, Burchert, S, Fuhr, DC, Huizink, AC, de Jong, J, Kieft, B, Knaevelsrud, C, McDaid, D, Morina, N, Park, A-L, Uppendahl, J, Ventevogel, P, Whitney, C, Wiedemann, N, Woodward, A, Sijbrandij, M, de Graaff, AM, Cuijpers, P, Acarturk, C, Bryant, R, Burchert, S, Fuhr, DC, Huizink, AC, de Jong, J, Kieft, B, Knaevelsrud, C, McDaid, D, Morina, N, Park, A-L, Uppendahl, J, Ventevogel, P, Whitney, C, Wiedemann, N, Woodward, A, and Sijbrandij, M
- Abstract
Background: Syrian refugees face multiple hardships and adversities which put them at risk for the development of mental health problems. However, access to adequate mental health care in host countries is limited. The WHO has developed Problem Management Plus (PM+), a brief, scalable psychological intervention, delivered by non-specialist helpers, that addresses common mental disorders in people affected by adversity. This study is part of the STRENGTHS project, that aims to evaluate peer-refugee delivered psychological interventions for Syrian refugees in Europe and the Middle East. Objective: To evaluate the effectiveness and cost-effectiveness of the peer-refugee delivered PM+ intervention among Syrian refugees with elevated levels of psychological distress in the Netherlands. Methods: PM+ will be tested in a randomized controlled trial (RCT) among Arabic-speaking Syrian refugees in the Netherlands aged 18 years and above with self-reported psychological distress (Kessler Psychological Distress Scale; K10 >15) and impaired daily functioning (WHO Disability Assessment Schedule; WHODAS 2.0 >16). Participants (N = 380) will be randomized into care as usual with PM+ (CAU/PM+, n = 190) or CAU only (CAU, n = 190). Baseline, 1-week post-intervention, and 3-month and 12-month follow-up assessments will be conducted. Primary outcomes are symptoms of depression and anxiety. Secondary outcomes are functional impairment, posttraumatic stress disorder symptoms, self-identified problems, anger, health and productivity costs, and hair cortisol concentrations. A process evaluation will be carried out to evaluate treatment dose, protocol fidelity and stakeholder views on barriers and facilitators to implementing PM+. Results and Conclusions: PM+ has proved effectiveness in other populations and settings. After positive evaluation, the adapted manual and training materials for individual PM+ will be made available through the WHO to encourage further replication and scaling up. T
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- 2020
23. Protocol for a randomized controlled trial: peer-to-peer Group Problem Management Plus (PM+) for adult Syrian refugees in Turkey.
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Uygun, E, Ilkkursun, Z, Sijbrandij, M, Aker, AT, Bryant, R, Cuijpers, P, Fuhr, DC, de Graaff, AM, de Jong, J, McDaid, D, Morina, N, Park, A-L, Roberts, B, Ventevogel, P, Yurtbakan, T, Acarturk, C, STRENGHTS consortium, Uygun, E, Ilkkursun, Z, Sijbrandij, M, Aker, AT, Bryant, R, Cuijpers, P, Fuhr, DC, de Graaff, AM, de Jong, J, McDaid, D, Morina, N, Park, A-L, Roberts, B, Ventevogel, P, Yurtbakan, T, Acarturk, C, and STRENGHTS consortium
- Abstract
BACKGROUND: A large proportion of Syrians have been exposed to potentially traumatic events, multiple losses, and breakdown of supportive social networks and many of them have sought refuge in host countries where they also face post-migration living difficulties such as discrimination or integration problems or both. These adversities may put Syrian refugees at high risk for common mental disorders. In response to this, the World Health Organization (WHO) developed a trans-diagnostic scalable psychological intervention called Problem Management Plus (PM+) to reduce psychological distress among populations exposed to adversities. PM+ has been adapted for Syrian refugees and can be delivered by non-specialist peer lay persons in the community. METHODS: A randomized controlled trial (RCT) will be conducted with 380 Syrian refugees in Turkey. After providing informed consent, participants with high levels of psychological distress (scoring above 15 on the Kessler-10 Psychological Distress Scale (K10)) and functional impairment (scoring above 16 on the WHO Disability Assessment Schedule 2.0, or WHODAS 2.0) will be randomly assigned to Group PM+/enhanced care as usual (Group PM+/E-CAU) (n = 190) or E-CAU (n = 190). Outcome assessments will take place 1 week after the fifth session (post-assessment), 3 months after the fifth session and 12 months after baseline assessment. The primary outcome is psychological distress as measured by the Hopkins Symptom Checklist (HSCL-25). Secondary outcomes include functional impairment, post-traumatic stress symptoms, self-identified problems, and health system and productivity costs. A process evaluation will be conducted to explore the feasibility, challenges and success of the intervention with 25 participants, including participants, facilitators, policy makers and mental health professionals. DISCUSSION: The treatment manual of the Syrian-Arabic Group PM+ and training materials will be made available through the WHO once the effect
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- 2020
24. Effectiveness of group problem management plus in distressed Syrian refugees in Türkiye: a randomized controlled trial
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Acarturk, C., Kurt, G., İlkkurşun, Z., de Graaff, A. M., Bryant, R., Cuijpers, P., Fuhr, D., McDaid, D., Park, A. L., Sijbrandij, M., Ventevogel, P., and Uygun, E.
- Abstract
AbstractAimsDespite high levels of psychological distress, mental health service use among Syrian refugees in urban settings is low. To address the mental healthcare gap, the World Health Organization developed group problem management plus (gPM+), a scalable psychological intervention delivered by non-specialist peer facilitators. The study aimed to evaluate the effectiveness of gPM+ in reducing symptoms of depression and anxiety among Syrian refugees in Istanbul, Türkiye.MethodsA randomized controlled trial was conducted among 368 distressed (Kessler Psychological Distress Scale, K10 > 15) adult Syrian refugees with impaired functioning (World Health Organization Disability Assessment Schedule, WHODAS 2.0 > 16). Participants were recruited between August 2019 and September 2020 through a non-governmental organization providing services to refugees. Participants were randomly allocated to gPM+ and enhanced care as usual (gPM+/E-CAU) (184 participants) or E-CAU only (184 participants). Primary outcomes were symptoms of depression and anxiety (Hopkins Symptom Checklist (HSCL-25)) at 3-month follow-up. Secondary outcomes were post-traumatic stress disorder (PTSD) symptoms (PTSD Checklist for Diagnostic and Statistical Manual of Mental Disorders-5; PCL-5), functional impairment (WHODAS 2.0), and self-identified problems (psychological outcome profiles).ResultsIntent-to-treat analyses showed no significant effect of gPM+ on symptoms of anxiety, depression, PTSD and self-identified problems. Yet, there was a significant reduction in functional impairment in gPM+/E-CAU compared to E-CAU at 3-month follow-up (adjusted mean difference 1.66, 95 % CI 0.04, 3.27, p= 0.045, d= 0.19). Post-hoc subgroup analyses among participants with probable baseline depression or anxiety showed that there was a small but significant reduction in depression (adjusted mean difference −0.17, 95 % CI −0.32, −0.02, p= 0.028, d= 0.27) and anxiety (adjusted mean difference −0.21, 95 % CI −0.37, −0.05, p= 0.009, d= 0.30) symptoms comparing gPM+/E-CAU to E-CAU only at 1-week post assessment, but not at 3-month follow-up. There was a significant difference between conditions on functional impairment at 3-month follow-up, favouring gPM+/E-CAU condition (adjusted mean difference −1.98, 95 % CI −3.93, −0.02, p= 0.048, d= 0.26).ConclusionIn this study in an urban setting in Türkiye, gPM+ did not alleviate symptoms of depression and anxiety among Syrian refugees experiencing psychological distress and daily living difficulties. However, participants with higher distress at baseline seemed to benefit from gPM+, but treatment gains disappeared in the long term. Current findings highlight the potential benefit of tailored psychosocial interventions for highly distressed refugees in volatile low-resource settings.
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- 2024
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25. Prevalence of common mental disorders among Syrian refugee children and adolescents in Sultanbeyli district, Istanbul: results of a population-based survey
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Scherer, N., primary, Hameed, S., additional, Acarturk, C., additional, Deniz, G., additional, Sheikhani, A., additional, Volkan, S., additional, Örücü, A., additional, Pivato, I., additional, Akıncı, İ., additional, Patterson, A., additional, and Polack, S., additional
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- 2020
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26. Treatment gap and mental health service use among Syrian refugees in Sultanbeyli, Istanbul: a cross-sectional survey
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Fuhr, D. C., primary, Acarturk, C., additional, McGrath, M., additional, Ilkkursun, Z., additional, Sondorp, E., additional, Sijbrandij, M., additional, Ventevogel, P., additional, Cuijpers, P., additional, McKee, M., additional, and Roberts, B., additional
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- 2019
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27. Strengthening mental health care systems for Syrian refugees in Europe and the Middle East: integrating scalable psychological interventions in 8 countries
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Sijbrandij, M., Acarturk, C., Bird, M., Bryant, R.A., Burchert, S., Carswell, K., Dinesen, C., Dawson, K., Chammay, R.E., van Ittersum, L., de Jong, J., Jordans, M., Knaevelsrud, C., McDaid, D., Morina, N., Miller, K., Park, A.L., Roberts, B., van Son, Y., Sondorp, E., Pfaltz, M.C., Ruttenberg, L., Schick, M., Schnyder, U., van Ommeren, M., Ventevogel, P., Weissbecker, I., Weitz, E., Wiedemann, N., Whitney, C., Cuijpers, P., Clinical Psychology, APH - Mental Health, APH - Global Health, and Clinical, Neuro- & Developmental Psychology
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RA0421 Public health. Hygiene. Preventive Medicine ,fungi - Abstract
The crisis in Syria has resulted in vast numbers of refugees seeking asylum in Syria’s neighbouring countries as well as in Europe. Refugees are at considerable risk of developing common mental disorders, including depression, anxiety, and posttraumatic stress disorder (PTSD). Most refugees do not have access to mental health services for these problems because of multiple barriers in national and refugee specific health systems, including limited availability of mental health professionals. To counter some of challenges arising from limited mental health system capacity the World Health Organization (WHO) has developed a range of scalable psychological interventions aimed at reducing psychological distress and improving functioning in people living in communities affected by adversity. These interventions, including Problem Management Plus (PM+) and its variants, are intended to be delivered through individual or group face-to-face or smartphone formats by lay, non-professional people who have not received specialized mental health training,We provide an evidence-based rationale for the use of the scalable PM+ oriented programmes being adapted for Syrian refugees and provide information on the newly launched STRENGTHS programme for adapting, testing and scaling up of PM+ in various modalities in both neighbouring and European countries hosting Syrian refugees.La crisis en Siria ha dado lugar a un gran número de refugiados que buscan asilo en países vecinos a Siria, así como en Europa. Los refugiados corren un riesgo considerable de desarrollar trastornos mentales comunes, como depresión, ansiedad y trastorno por estrés postraumático (TEPT). La mayoría de los refugiados no tienen acceso a servicios de salud mental para estos problemas debido a las múltiples barreras existentes en los sistemas de salud nacionales y específicos para refugiados, incluida una limitada disponibilidad de profesionales de salud mental. Para contrarrestar algunos de los retos derivados de la limitada capacidad del sistema de salud mental, la Organización Mundial de la Salud (OMS) ha desarrollado una gama de intervenciones psicológicas escalables dirigidas a reducir la angustia psicológica y mejorar el funcionamiento de las personas afectadas por la adversidad. Estas intervenciones, que incluyen Problem Management Plus (Gestión de problemas plus, PM+) y sus variantes, están pensadas para ser aplicadas en formatos cara a cara o mediante teléfonos inteligentes a individuos o grupos por personas no profesionales que no han recibido formación especializada en salud mental,Proporcionamos una justificación basada en la evidencia para el uso de programas escalables orientados a la PM+ que están siendo adaptados para refugiados sirios y proporcionamos información sobre el programa STRENGTHS recientemente lanzado para adaptar, probar y ampliar la PM+ en diversas modalidades, tanto en los países vecinos como en los europeos que reciben refugiados de Siria. 叙利亚危机导致了海量的难民到周边国家和欧洲寻求避难所。难民们发展出常见心理障碍的风险非常大,其中包括抑郁,焦虑,创伤后应激障碍(PTSD)。大多数难民没有渠道向心理健康机构寻求帮助,这主要是因为国家医疗和难民健康系统的种种阻碍,包括心理健康专家的数量不足。为了应对心理健康系统容量有限所产生的问题,世界卫生组织(WHO)发展出了一系列的可量化心理干预方法,用来减少心理障碍和提高社区中处于逆境里的人们的生活功能。这些干预方法中就有《问题应对量表Plus》(PM+)和它的其他变型,用来给未经过专业心理健康训练的非专业新手以面对面的或智能手机的形式向个人或群体使用。我们为针对叙利亚难民改良的可量化的PM+为基础的项目提供了有证据支持的原理,并且提供了关于新近运行的STRENGTHS项目的信息,该项目旨在在接受叙利亚难民的周边国家和欧洲国家中适应、测试、扩大PM+的多种形式。
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- 2017
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28. Efficacy and acceptability of psychosocial interventions in asylum seekers and refugees: systematic review and meta-analysis
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Turrini, G., primary, Purgato, M., additional, Acarturk, C., additional, Anttila, M., additional, Au, T., additional, Ballette, F., additional, Bird, M., additional, Carswell, K., additional, Churchill, R., additional, Cuijpers, P., additional, Hall, J., additional, Hansen, L. J., additional, Kösters, M., additional, Lantta, T., additional, Nosè, M., additional, Ostuzzi, G., additional, Sijbrandij, M., additional, Tedeschi, F., additional, Valimaki, M., additional, Wancata, J., additional, White, R., additional, van Ommeren, M., additional, and Barbui, C., additional
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- 2019
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29. Treatment gap and mental health service use among Syrian refugees in Sultanbeyli, Istanbul: a cross-sectional survey.
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Fuhr, D. C., Acarturk, C., McGrath, M., Ilkkursun, Z., Sondorp, E., Sijbrandij, M., Ventevogel, P., Cuijpers, P., McKee, M., and Roberts, B.
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MENTAL health services ,SYRIAN refugees ,POST-traumatic stress disorder ,SURGERY safety measures ,MENTAL health ,ATTITUDE (Psychology) ,NURSES' attitudes - Abstract
Aims: Syrian refugees may have increased mental health needs due to the frequent exposure to potentially traumatic events and violence experienced during the flight from their home country, breakdown of supportive social networks and daily life stressors related to refugee life. The aim of this study is to report evidence on mental health needs and access to mental health and psychosocial support (MHPSS) among Syrians refugees living in Sultanbeyli-Istanbul, Turkey. Methods: A cross-sectional survey was conducted among Syrian refugees aged 18 years or over in Sultanbeyli between February and May 2018. We used random sampling to select respondents by using the registration system of the municipality. Data among 1678 Syrian refugees were collected on mental health outcomes using the Posttraumatic Stress Disorder (PTSD) Checklist (PCL-5) and the Hopkins Symptoms Checklist (HSCL-25) for depression and anxiety. We also collected data on health care utilisation, barriers to seeking and continuing care as well as knowledge and attitudes towards mental health. Descriptive analyses were used. Results: The estimated prevalence of symptoms of PTSD, depression and anxiety was 19.6, 34.7 and 36.1%, respectively. In total, 249 respondents (15%) screened positive for either PTSD, depression or anxiety in our survey and self-reported emotional/behavioural problems since arriving in Sultanbeyli. The treatment gap (the proportion of these 249 people who did not seek care) was 89% for PTSD, 90% for anxiety and 88% for depression. Several structural and attitudinal barriers for not seeking care were reported, including the cost of mental health care, the belief that time would improve symptoms, fear of being stigmatised and lack of knowledge on where and how to get help. Some negative attitudes towards people with mental health problems were reported by respondents. Conclusions: Syrian refugees hardly access MHPSS services despite high mental health needs, and despite formally having access to the public mental health system in Turkey. To overcome the treatment gap, MHPSS programmes need to be implemented in the community and need to overcome the barriers to seeking care which were identified in this study. Mental health awareness raising activities should be provided in the community alongside the delivery of psychological interventions. This is to increase help-seeking and to tackle negative attitudes towards mental health and people with mental health problems. [ABSTRACT FROM AUTHOR]
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- 2020
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30. Towards better child protection programmes: a qualitative evaluation of Youth Disseminating Life Skills Programme
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Krespi, MR, primary, Acarturk, C, additional, Akduman-Akin, I, additional, Sahin Dagli, F, additional, and Dagli, T, additional
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- 2017
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31. Strengthening mental health care systems for Syrian refugees in Europe and the Middle East: integrating scalable psychological interventions in eight countries
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Sijbrandij, M, Acarturk, C, Bird, M, Bryant, RA, Burchert, S, Carswell, K, de Jong, J, Dinesen, C, Dawson, KS, El Chammay, R, van Ittersum, L, Jordans, M, Knaevelsrud, C, McDaid, D, Miller, K, Morina, N, Park, AL, Roberts, B, van Son, Y, Sondorp, E, Pfaltz, MC, Ruttenberg, L, Schick, M, Schnyder, U, van Ommeren, M, Ventevogel, P, Weissbecker, I, Weitz, E, Wiedemann, N, Whitney, C, Cuijpers, P, Sijbrandij, M, Acarturk, C, Bird, M, Bryant, RA, Burchert, S, Carswell, K, de Jong, J, Dinesen, C, Dawson, KS, El Chammay, R, van Ittersum, L, Jordans, M, Knaevelsrud, C, McDaid, D, Miller, K, Morina, N, Park, AL, Roberts, B, van Son, Y, Sondorp, E, Pfaltz, MC, Ruttenberg, L, Schick, M, Schnyder, U, van Ommeren, M, Ventevogel, P, Weissbecker, I, Weitz, E, Wiedemann, N, Whitney, C, and Cuijpers, P
- Abstract
The crisis in Syria has resulted in vast numbers of refugees seeking asylum in Syria’s neighbouring countries as well as in Europe. Refugees are at considerable risk of developing common mental disorders, including depression, anxiety, and posttraumatic stress disorder (PTSD). Most refugees do not have access to mental health services for these problems because of multiple barriers in national and refugee specific health systems, including limited availability of mental health professionals. To counter some of challenges arising from limited mental health system capacity the World Health Organization (WHO) has developed a range of scalable psychological interventions aimed at reducing psychological distress and improving functioning in people living in communities affected by adversity. These interventions, including Problem Management Plus (PM+) and its variants, are intended to be delivered through individual or group face-to-face or smartphone formats by lay, non-professional people who have not received specialized mental health training, We provide an evidence-based rationale for the use of the scalable PM+ oriented programmes being adapted for Syrian refugees and provide information on the newly launched STRENGTHS programme for adapting, testing and scaling up of PM+ in various modalities in both neighbouring and European countries hosting Syrian refugees.
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- 2017
32. Strengthening mental health care systems for Syrian refugees in Europe and the Middle East : integrating scalable psychological interventions in eight countries
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Sijbrandij, M., Acarturk, C., Bird, M., Bryant, R. A., Burchert, S., Carswell, K., de Jong, J., Dinesen, C., Dawson, K. S., El Chammay, R., van Ittersum, L., Jordans, M., Knaevelsrud, C., McDaid, D., Miller, K., Morina, N., Park, A. -L, Roberts, B., van Son, Y., Sondorp, E., Pfaltz, Monique C., Ruttenberg, L., Schick, M., Schnyder, U., van Ommeren, M., Ventevogel, P., Weissbecker, I., Weitz, E., Wiedemann, N., Whitney, C., Cuijpers, P., Sijbrandij, M., Acarturk, C., Bird, M., Bryant, R. A., Burchert, S., Carswell, K., de Jong, J., Dinesen, C., Dawson, K. S., El Chammay, R., van Ittersum, L., Jordans, M., Knaevelsrud, C., McDaid, D., Miller, K., Morina, N., Park, A. -L, Roberts, B., van Son, Y., Sondorp, E., Pfaltz, Monique C., Ruttenberg, L., Schick, M., Schnyder, U., van Ommeren, M., Ventevogel, P., Weissbecker, I., Weitz, E., Wiedemann, N., Whitney, C., and Cuijpers, P.
- Abstract
The crisis in Syria has resulted in vast numbers of refugees seeking asylum in Syriaâs neighbouring countries as well as in Europe. Refugees are at considerable risk of developing common mental disorders, including depression, anxiety, and posttraumatic stress disorder (PTSD). Most refugees do not have access to mental health services for these problems because of multiple barriers in national and refugee specific health systems, including limited availability of mental health professionals. To counter some of challenges arising from limited mental health system capacity the World Health Organization (WHO) has developed a range of scalable psychological interventions aimed at reducing psychological distress and improving functioning in people living in communities affected by adversity. These interventions, including Problem Management Plus (PM+) and its variants, are intended to be delivered through individual or group face-to-face or smartphone formats by lay, non-professional people who have not received specialized mental health training, We provide an evidence-based rationale for the use of the scalable PM+ oriented programmes being adapted for Syrian refugees and provide information on the newly launched STRENGTHS programme for adapting, testing and scaling up of PM+ in various modalities in both neighbouring and European countries hosting Syrian refugees. © 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
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- 2017
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33. Personalized psychotherapy for adult depression: A meta-analytic review
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Cuijpers, Pim, Ebert, D.D., Acarturk, C., Andersson, G., Cristea, I.A., Cuijpers, Pim, Ebert, D.D., Acarturk, C., Andersson, G., and Cristea, I.A.
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- 2016
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34. The efficacy of eye movement desensitization and reprocessing for post-traumatic stress disorder and depression among Syrian refugees: results of a randomized controlled trial
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Acarturk, C., primary, Konuk, E., additional, Cetinkaya, M., additional, Senay, I., additional, Sijbrandij, M., additional, Gulen, B., additional, and Cuijpers, P., additional
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- 2016
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35. EMDR for Syrian refugees with posttraumatic stress disorder symptoms:results of a pilot randomized controlled trial
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Acarturk, C., Konuk, E., Cetinkaya, M., Senay, I., Sijbrandij, M., Cuijpers, P., Aker, T., Acarturk, C., Konuk, E., Cetinkaya, M., Senay, I., Sijbrandij, M., Cuijpers, P., and Aker, T.
- Abstract
Background: The most common mental health problems among refugees are depression and posttraumatic stress disorder (PTSD). Eye movement desensitization and reprocessing (EMDR) is an effective treatment for PTSD. However, no previous randomized controlled trial (RCT) has been published on treating PTSD symptoms in a refugee camp population. Objective: Examining the effect of EMDR to reduce the PTSD and depression symptoms compared to a wait-list condition among Syrian refugees. Method: Twenty-nine adult participants with PTSD symptoms were randomly allocated to either EMDR sessions (n = 15) or wait-list control (n = 14). The main outcome measures were Impact of Event Scale-Revised (IES-R) and Beck Depression Inventory (BDI-II) at posttreatment and 4-week follow-up. Results: Analysis of covariance showed that the EMDR group had significantly lower trauma scores at posttreatment as compared with the wait-list group (d=1.78,95% CI: 0.92-2.64). The EMDR group also had a lower depression score after treatment as compared with the wait-list group (d= 1.14, 95% CI: 0.35-1.92). Conclusion: The pilot RCT indicated that EMDR may be effective in reducing PTSD and depression symptoms among Syrian refugees located in a camp. Larger RCTs to verify the (cost-) effectiveness of EMDR in similar populations are needed.
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- 2015
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36. Epidemiology and Treatment of Social Phobia
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Acarturk, C., Cuijpers, Pim, van Straten, Annemieke, de Graaf, R., Clinical Psychology, and EMGO+ - Mental Health
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- 2009
37. Incidence of social phobia and identification of its risk indicators: a model for prevention
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Acarturk, C., primary, Smit, F., additional, De Graaf, R., additional, Van Straten, A., additional, Ten Have, M., additional, and Cuijpers, P., additional
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- 2008
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38. Psychological treatment of social anxiety disorder: a meta-analysis
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Acarturk, C., primary, Cuijpers, P., additional, van Straten, A., additional, and de Graaf, R., additional
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- 2008
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39. Group problem management plus (PM+) to decrease psychological distress among Syrian refugees in Turkey: a pilot randomised controlled trial
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Acarturk, C., Uygun, E., Ilkkursun, Z., Yurtbakan, T., Kurt, G., Adam-Troian, J., Senay, I., Bryant, R., Cuijpers, P., Kiselev, N., McDaid, David, Morina, N., Nisanci, Z., Park, A-La, Sijbrandij, M., Ventevogel, P., Fuhr, D. C., Acarturk, C., Uygun, E., Ilkkursun, Z., Yurtbakan, T., Kurt, G., Adam-Troian, J., Senay, I., Bryant, R., Cuijpers, P., Kiselev, N., McDaid, David, Morina, N., Nisanci, Z., Park, A-La, Sijbrandij, M., Ventevogel, P., and Fuhr, D. C.
- Abstract
BACKGROUND: Syrian refugees resettled in Turkey show a high prevalence of symptoms of mental disorders. Problem Management Plus (PM+) is an effective psychological intervention delivered by non-specialist health care providers which has shown to decrease psychological distress among people exposed to adversity. In this single-blind pilot randomised controlled trial, we examined the methodological trial procedures of Group PM+ (gPM+) among Syrian refugees with psychological distress in Istanbul, Turkey, and assessed feasibility, acceptability, perceived impact and the potential cost-effectiveness of the intervention. METHODS: Refugees with psychological distress (Kessler Psychological Distress Scale, K10 > 15) and impaired psychosocial functioning (World Health Organization Disability Assessment Schedule, WHODAS 2.0 > 16) were recruited from the community and randomised to either gPM+ and enhanced care as usual (E-CAU) (n = 24) or E-CAU only (n = 22). gPM+ comprised of five weekly group sessions with eight to ten participants per group. Acceptability and feasibility of the intervention were assessed through semi-structured interviews. The primary outcome at 3-month follow-up was symptoms of depression and anxiety (Hopkins Symptoms Checklist-25). Psychosocial functioning (WHODAS 2.0), symptoms of posttraumatic stress disorder and self-identified problems (Psychological Outcomes Profiles, PSYCHLOPS) were included as secondary outcomes. A modified version of the Client Service Receipt Inventory was used to document changes in the costs of health service utilisation as well as productivity losses. RESULTS: There were no barriers experienced in recruiting study participants and in randomising them into the respective study arms. Retention in gPM+ was high (75%). Qualitative analyses of the interviews with the participants showed that Syrian refugees had a positive view on the content, implementation and format of gPM+. No adverse events were reported during the implementa
40. The Türkiye-Syria earthquake region.
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Kurt G, Almeamari F, El-Dardery H, Lekkeh S, Acarturk C, Rosenbaum S, and Wells R
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- 2024
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41. The effectiveness of Problem Management Plus at 1-year follow-up for Syrian refugees in a high-income setting.
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de Graaff AM, Cuijpers P, Elsawy M, Hunaidy S, Kieft B, Gorgis N, Twisk JWR, Zakarian Y, Bouman TK, Lommen MJJ, Acarturk C, Bryant R, McDaid D, Morina N, Park AL, Ventevogel P, and Sijbrandij M
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- Humans, Syria ethnology, Adult, Female, Male, Follow-Up Studies, Netherlands, Single-Blind Method, Psychological Distress, Depression therapy, Depression psychology, Middle Aged, Stress, Psychological therapy, Stress, Psychological psychology, Treatment Outcome, Mental Disorders therapy, Mental Disorders psychology, Mental Disorders ethnology, Refugees psychology, Stress Disorders, Post-Traumatic therapy, Stress Disorders, Post-Traumatic psychology, Anxiety therapy, Anxiety psychology
- Abstract
Aims: Problem Management Plus (PM+) has been effective in reducing mental health problems among refugees at three-month follow-up, but there is a lack of research on its long-term effectiveness. This study examined the effectiveness of PM+ in reducing symptoms of common mental disorders at 12-month follow-up among Syrian refugees in the Netherlands., Methods: This single-blind, parallel, controlled trial randomised 206 adult Syrians who screened positive for psychological distress and impaired functioning to either PM+ in addition to care as usual (PM+/CAU) or CAU alone. Assessments were at baseline, 1 week and 3 months after the intervention and 12 months after baseline. Outcomes were psychological distress (Hopkins Symptom Checklist [HSCL-25]), depression (HSCL-25 subscale), anxiety (HSCL-25 subscale), posttraumatic stress disorder symptoms (PCL-5), functional impairment (WHODAS 2.0) and self-identified problems (PSYCHLOPS)., Results: In March 2019-December 2022, 103 participants were assigned to PM+/CAU and 103 to CAU of which 169 (82.0%) were retained at 12 months. Intention-to-treat analyses showed greater reductions in psychological distress at 12 months for PM+/CAU compared to CAU (adjusted mean difference -0.17, 95% CI -0.310 to -0.027; p = 0.01, Cohen's d = 0.28). Relative to CAU, PM+/CAU participants also showed significant reductions on anxiety (-0.19, 95% CI -0.344 to -0.047; p = 0.01, d = 0.31) but not on any of the other outcomes., Conclusions: PM+ is effective in reducing psychological distress and symptoms of anxiety over a period up to 1 year. Additional support such as booster sessions or additional (trauma-focused) modules may be required to prolong and consolidate benefits gained through PM+ on other mental health and psychosocial outcomes.
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- 2024
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42. Syrian refugee women's experiences of barriers to mental health services for postpartum depression.
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Salameh TN, Sakarya S, Acarturk C, Hall LA, Al-Modallal H, and Jakalat SS
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Objective: To describe Syrian refugee women's experiences of the barriers to access mental health services for postpartum depression (PPD)., Design: A descriptive qualitative study was conducted., Methods: Fifteen purposefully selected Syrian refugee women who scored ≥10 on the Edinburgh Postnatal Depression Scale participated in the semi-structured telephone interviews. Transcripts were coded verbatim and analysed thematically according to the dimensions of Levesque's model of patient-centred access to healthcare. Data were collected between August 2022 and February 2023., Results: Five themes with 14 subthemes were identified: (1) approachability covered lack of knowledge and misconceptions related to PPD and its treatment, lack of awareness of available psychosocial services and perceived need of mental health treatment; (2) acceptability comprised being a refugee, stigma of mental illness, cultural preferences of healthcare provider and language barrier; (3) availability and accommodation encompassed transportation barrier and location of the centre, no support for childcare and lack of time; (4) affordability included financial difficulties and health insurance coverage; (5) appropriateness comprised no screening for PPD and intermittent services with limited focus on mental health., Conclusions: The findings of this study reveal that Syrian refugee women experienced multi-faceted complex barriers to access mental health services for PPD. It is important for health professionals, including nurses, and policymakers to address the cultural mental health needs of this population and establish strategies to protect their legal and health rights., Impact: Our study has important practice and policy implications for establishing strategies designed specifically for refugee mothers to mitigate their perceived barriers to PPD treatment and ultimately improve their mental health., Reporting Method: The Consolidated Criteria for Reporting Qualitative Research was used., Patient or Public Contribution: No patient or public contribution. Participants were Syrian refugee women with PPD symptoms and contributed only to the interviews and member checking., (© 2024 The Author(s). Journal of Advanced Nursing published by John Wiley & Sons Ltd.)
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- 2024
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43. How to distinguish promotion, prevention and treatment trials in public mental health? Study protocol for the development of the VErona-LUgano Tool (VELUT).
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Purgato M, Albanese E, Papola D, Prina E, Tedeschi F, Gross A, Sijbrandij M, Acarturk C, Annoni AM, Silva M, Jordans MJD, Lund C, Tol WA, Cuijpers P, and Barbui C
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- Humans, Mental Health, Psychometrics, Reproducibility of Results, Delphi Technique, Mental Disorders therapy, Mental Disorders diagnosis, Randomized Controlled Trials as Topic, Public Health, Research Design, Health Promotion methods
- Abstract
Introduction: Promoting mental health, preventing and treating mental disorders are critically important in public health, and many randomised controlled trials (RCTs) evaluate intervention strategies for these objectives. However, distinguishing promotion from prevention and from treatment RCTs is challenging. A tool to place studies along the promotion-to-treatment continuum in mental health research does not exist, leaving it to researchers and policymakers to decide on how to classify individual RCTs, which hinders evidence synthesis., Methods and Analysis: We present a protocol for the development of a new tool to assist researchers in distinguishing RCTs along the promotion-to-treatment continuum. We will establish a Tool Development Group, and use the Population, Intervention, Comparison and Outcome framework to define constructs. We will generate, define, categorise and reduce the items in the tool using qualitative methods, including cognitive interviews and a Delphi exercise. Psychometric evaluation-including unidimensionality, local independence, monotonicity and item homogeneity-will include data collection, scoring, internal consistency checks and factor analysis of the tool's indicators for available RCTs. We will use standard Cohen's kappa statistics to assess the reliability of the tool., Ethics and Dissemination: This study involves data collection from the already published literature. However, this protocol has been approved by the ethics committee of the Università della Svizzera Italiana (CE 2024 04). The results of the present project will be disseminated in peer-reviewed journals and at international and national scientific meetings. Training materials for the application of the tool will also be developed and disseminated to the scientific community. The tool and all related implementation materials will be published on a website and will be freely accessible to the public., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
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- 2024
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44. Health system responsiveness to the mental health needs of Syrian refugees: mixed-methods rapid appraisals in eight host countries in Europe and the Middle East.
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Woodward A, Fuhr DC, Barry AS, Balabanova D, Sondorp E, Dieleman MA, Pratley P, Schoenberger SF, McKee M, Ilkkursun Z, Acarturk C, Burchert S, Knaevelsrud C, Brown FL, Steen F, Spaaij J, Morina N, de Graaff AM, Sijbrandij M, Cuijpers P, Bryant R, Akhtar A, and Roberts B
- Abstract
Background: Syrian refugees have a high burden of mental health symptoms and face challenges in accessing mental health and psychosocial support (MHPSS). This study assesses health system responsiveness (HSR) to the MHPSS needs of Syrian refugees, comparing countries in Europe and the Middle East to inform recommendations for strengthening MHPSS systems., Methods: A mixed-methods rapid appraisal methodology guided by an adapted WHO Health System Framework was used to assess HSR in eight countries (Egypt, Germany, Jordan, Lebanon, Netherlands, Sweden, Switzerland, and Türkiye). Quantitative and qualitative analysis of primary and secondary data was used. Data collection and analysis were performed iteratively by multiple researchers. Country reports were used for comparative analysis and synthesis., Results: We found numerous constraints in HSR: i) Too few appropriate mental health providers and services; ii) Travel-related barriers impeding access to services, widening rural-urban inequalities in the distribution of mental health workers; iii) Cultural, language, and knowledge-related barriers to timely care likely caused by insufficient numbers of culturally sensitive providers, costs of professional interpreters, somatic presentations of distress by Syrian refugees, limited mental health awareness, and stigma associated to mental illness; iv) High out-of-pocket costs for psychological treatment and transportation to services reducing affordability, particularly in middle-income countries; v) Long waiting times for specialist mental health services; vi) Information gaps on the mental health needs of refugees and responsiveness of MHPSS systems in all countries. Six recommendations are provided to address these issues., Conclusions: All eight host countries struggle to provide responsive MHPSS to Syrian refugees. Strengthening the mental health workforce (in terms of quantity, quality, diversity, and distribution) is urgently needed to enable Syrian refugees to receive culturally appropriate and timely care and improve mental health outcomes. Increased financial investment in mental health and improved health information systems are crucial., Competing Interests: No competing interests were disclosed., (Copyright: © 2024 Woodward A et al.)
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- 2024
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45. Understanding the protective effect of social support on depression symptomatology from a longitudinal network perspective.
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Li G, Li Y, Lam AIF, Tang W, Seedat S, Barbui C, Papola D, Panter-Brick C, Waerden JV, Bryant R, Mittendorfer-Rutz E, Gémes K, Purba FD, Setyowibowo H, Pinucci I, Palantza C, Acarturk C, Kurt G, Tarsitani L, Morina N, Burchert S, Patanè M, Quero S, Campos D, Huizink AC, Fuhr DC, Spiller T, Sijbrandij M, and Hall BJ
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- Male, Adult, Humans, Female, Social Support, Loneliness psychology, Social Networking, Depression prevention & control, Mental Disorders
- Abstract
Background: Higher social support protects people from developing mental disorders. Limited evidence is available on the mechanism through which social support plays this protective role., Objective: To investigate the stress-buffering process of social support on depressive symptoms using a novel longitudinal dynamic symptom network approach., Methods: A total of 4242 adult participants who completed the first two waves (from May to October 2020) of the International Covid Mental Health Survey were included in the study. Cross-lagged panel network modelling was used to estimate a longitudinal network of self-reported social support, loneliness and depressive symptoms. Standardised regression coefficients from regularised cross-lagged regressions were estimated as edge weights of the network., Findings: The results support a unidirectional protective effect of social support on key depressive symptoms, partly mediated through loneliness: A higher number of close confidants and accessible practical help was associated with decreased anhedonia (weight=-0.033) and negative self-appraisal symptoms (weight=-0.038). Support from others was also negatively associated with loneliness, which in turn associated with decreased depressed mood (weight=0.086) and negative self-appraisal (weight=0.077). We identified a greater number of direct relationships from social support to depressive symptoms among men compared with women. Also, the edge weights from social support to depression were generally stronger in the men's network., Conclusions: Reductions in negative self-appraisal might function as a bridge between social support and other depressive symptoms, and, thus, it may have amplified the protective effect of social support. Men appear to benefit more from social support than women., Clinical Implications: Building community-based support networks to deliver practical support, and loneliness reduction components are critical for depression prevention interventions after stressful experiences., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. Published by BMJ.)
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- 2023
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46. Testing the effectiveness and acceptability of online supportive supervision for mental health practitioners in humanitarian settings: a study protocol for the caring for carers project.
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Wells R, Acarturk C, Mozumder MK, Kurt G, Klein L, Lekkeh SA, Beetar A, Jahan S, Almeamari F, Faruk MO, McGrath M, Alam SF, Alokoud M, Dewan R, Vecih AE, El-Dardery H, Hadzi-Pavlovic D, Hammadi H, Hamoud MAS, Hasan MT, Joshi R, Kothaa S, Lamia FKC, Mastrogiovanni C, Najjar H, Nemorin S, Nicholson-Perry K, Prokrity TS, Said Yousef R, Tawakol M, Uygun E, Yasaki W, Wong S, Zarate A, Steel Z, and Rosenbaum S
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- Humans, Mental Health, Caregivers, Quality of Life, Compassion Fatigue, Burnout, Professional prevention & control, Burnout, Professional psychology
- Abstract
Background: Local humanitarian workers in low and middle-income countries must often contend with potentially morally injurious situations, often with limited resources. This creates barriers to providing sustainable mental health and psychosocial support (MHPSS) to displaced individuals. Clinical supervision is an often neglected part of ensuring high-quality, sustainable care. The Caring for Carers (C4C) project aims to test the effectiveness and acceptability of online group-based supportive supervision on the well-being of MHPSS practitioners, as well as service-user-reported service satisfaction and quality when working with displaced communities in Türkiye, Syria, and Bangladesh. This protocol paper describes the aim, design, and methodology of the C4C project., Method: A quasi-experimental, mixed-method, community-based participatory research study will be conducted to test the effectiveness of online group-based supportive clinical supervision provided to 50 Syrian and 50 Bangladeshi MHPSS practitioners working with Syrian and Rohingya displaced communities. Monthly data will be collected from the practitioners and their beneficiaries during the active control (six months) and supervision period (16 months over two terms). Outcomes are psychological distress (Kessler-6), burnout (the Copenhagen Burnout Inventory), compassion fatigue, compassion satisfaction, and secondary traumatic stress (Professional Quality of Life Scale), perceived injustice, clinical self-efficacy (Counseling Activity Self-Efficacy Scale), service satisfaction, and quality (Client Satisfaction Questionnaire and an 18-item measure developed in this project). A realist evaluation framework will be used to elucidate the contextual factors, mechanisms, and outcomes of the supervision intervention., Discussion: There is a scarcity of evidence on the role of clinical supervision in improving the well-being of MHPSS practitioners and the quality of service they provide to displaced people. By combining qualitative and quantitative data collection, the C4C project will address the long-standing question of the effectiveness and acceptability of clinical supervision in humanitarian settings., (© 2023. The Author(s).)
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- 2023
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47. Impacts of the COVID-19 pandemic on access to healthcare among people with disabilities: evidence from six low- and middle-income countries.
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Hunt X, Hameed S, Tetali S, Ngoc LA, Ganle J, Huq L, Shakespeare T, Smythe T, Ilkkursun Z, Kuper H, Acarturk C, Kannuri NK, Mai VQ, Khan RS, and Banks LM
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- Humans, Developing Countries, Pandemics, Health Services Accessibility, COVID-19, Persons with Disabilities
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Background: The pandemic has placed considerable strain on health systems, especially in low- and middle-income countries (LMICs), leading to reductions in the availability of routine health services. Emerging evidence suggests that people with disabilities have encountered marked challenges in accessing healthcare services and supports in the context of the pandemic. Further research is needed to explore specific barriers to accessing healthcare during the pandemic, and any strategies that promoted continued access to health services in LMICs where the vast majority of people with disabilities live., Methods: Qualitative in-depth interviews were conducted with persons with disabilities in Ghana, Zimbabwe, Viet Nam, Türkiye (Syrian refugees), Bangladesh, and India as part of a larger project exploring the experiences of people with disabilities during the COVID-19 pandemic and their inclusion in government response activities. Data were analysed using thematic analysis., Results: This research found that people with disabilities in six countries - representing a diverse geographic spread, with different health systems and COVID-19 responses - all experienced additional difficulties accessing healthcare during the pandemic. Key barriers to accessing healthcare during the pandemic included changes in availability of services due to systems restructuring, difficulty affording care due to the economic impacts of the pandemic, fear of contracting coronavirus, and a lack of human support to enable care-seeking., Conclusion: These barriers ultimately led to decreased utilisation of services which, in turn, negatively impacted their health and wellbeing. However, we also found that certain factors, including active and engaged Organisations of Persons with Disabilities (OPDs) and Non-Governmental Organizations (NGOs) played a role in reducing some of the impact of pandemic-related healthcare access barriers., (© 2023. BioMed Central Ltd., part of Springer Nature.)
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- 2023
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48. Socio-cultural integration of Afghan refugees in Türkiye: the role of traumatic events, post-displacement stressors and mental health.
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Kurt G, Ekhtiari M, Ventevogel P, Ersahin M, Ilkkursun Z, Akbiyik N, and Acarturk C
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- Humans, Mental Health, Cross-Sectional Studies, Acculturation, Stress Disorders, Post-Traumatic psychology, Refugees psychology
- Abstract
Aims: Socio-cultural integration of refugees has received scant attention in the academic literature. Türkiye hosts the largest number of refugees, including Afghans, as the second largest asylum-seeking group in Türkiye. There is a dearth of research into the mental health and integration of Afghan refugees in Türkiye. The aim of the present study was to investigate socio-cultural integration outcomes among Afghan refugees in Türkiye by considering the role of traumatic events and post-displacement stressors. The role of mental health in integration outcomes was further examined., Methods: A cross-sectional, web-based survey study with 785 Afghan refugees in Türkiye was conducted between April and June 2021. Data were collected on socio-demographic characteristics, potentially traumatic events (PTEs) (Harvard Trauma Questionnaire), post-displacement stressors (Post-Migration Living Difficulties Checklist), mental health symptoms (Hopkins Symptoms Checklist-25), social integration- social bonds (contact with co-ethnic group members) and social bridges (contact with the host community)- and cultural integration (Vancouver Index of Acculturation). Structural equation modelling was conducted to test the hypothesized relationship between conflict and displacement-related stressors, mental health and socio-cultural integration., Results: Findings showed that conflict-related traumatic events and post-displacement stressors significantly predicted higher mental health symptoms. Experiencing traumatic events significantly predicted higher levels of social bridges, adopting destination culture and lower level of maintaining heritage culture. Mental health problems predicted the relationship between stressors related to forced displacement and integration outcomes-social bridges and adopting destination culture. These findings highlight the role of mental health as an indispensable resource for socio-cultural integration. Further, conflict and displacement-related stressors are important determinants of socio-cultural integration among Afghan refugees in Türkiye., Conclusion: Exposure to PTEs and post-displacement stressors were significant risk factors for the mental health and socio-cultural integration of Afghan refugees in Türkiye. These stressful experiences deteriorate refugees' mental health, which hinders their integration into the host society.
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- 2023
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49. A Naturalistic Setup for Presenting Real People and Live Actions in Experimental Psychology and Cognitive Neuroscience Studies.
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Pekçetin TN, Evsen Ş, Pekçetin S, Acarturk C, and Urgen BA
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- Humans, Cognition, Communication, Laboratories, Psychology, Experimental, Cognitive Neuroscience
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Perception of others' actions is crucial for survival, interaction, and communication. Despite decades of cognitive neuroscience research dedicated to understanding the perception of actions, we are still far away from developing a neurally inspired computer vision system that approaches human action perception. A major challenge is that actions in the real world consist of temporally unfolding events in space that happen "here and now" and are actable. In contrast, visual perception and cognitive neuroscience research to date have largely studied action perception through 2D displays (e.g., images or videos) that lack the presence of actors in space and time, hence these displays are limited in affording actability. Despite the growing body of knowledge in the field, these challenges must be overcome for a better understanding of the fundamental mechanisms of the perception of others' actions in the real world. The aim of this study is to introduce a novel setup to conduct naturalistic laboratory experiments with live actors in scenarios that approximate real-world settings. The core element of the setup used in this study is a transparent organic light-emitting diode (OLED) screen through which participants can watch the live actions of a physically present actor while the timing of their presentation is precisely controlled. In this work, this setup was tested in a behavioral experiment. We believe that the setup will help researchers reveal fundamental and previously inaccessible cognitive and neural mechanisms of action perception and will be a foundation for future studies investigating social perception and cognition in naturalistic settings.
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- 2023
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50. Self-Help Plus for refugees and asylum seekers: an individual participant data meta-analysis.
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Karyotaki E, Sijbrandij M, Purgato M, Acarturk C, Lakin D, Bailey D, Peckham E, Uygun E, Tedeschi F, Wancata J, Augustinavicius J, Carswell K, Välimäki M, van Ommeren M, Koesters M, Popa M, Leku MR, Anttila M, Churchill R, White RG, Al-Hashimi S, Lantta T, Au T, Klein T, Tol WA, Cuijpers P, and Barbui C
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- Humans, Mental Health, Health Behavior, Psychological Well-Being, Refugees psychology, Stress Disorders, Post-Traumatic therapy
- Abstract
Question: Refugees and asylum seekers are at high risk of mental disorders due to various stressors before, during and after forceful displacement. The WHO Self-Help Plus (SH+) intervention was developed to manage psychological distress and a broad range of mental health symptoms in vulnerable populations. This study aimed to examine the effects and moderators of SH+ compared with Enhanced Care as Usual (ECAU) in reducing depressive symptoms among refugees and asylum seekers., Study Selection and Analysis: Three randomised trials were identified with 1795 individual participant data (IPD). We performed an IPD meta-analysis to estimate the effects of SH+, primarily on depressive symptoms and second on post-traumatic stress, well-being, self-identified problems and functioning. Effects were also estimated at 5-6 months postrandomisation (midterm)., Findings: There was no evidence of a difference between SH+ and ECAU+ in reducing depressive symptoms at postintervention. However, SH+ had significantly larger effects among participants who were not employed (β=1.60, 95% CI 0.20 to 3.00) and had lower mental well-being levels (β=0.02, 95% CI 0.001 to 0.05). At midterm, SH+ was significantly more effective than ECAU in improving depressive symptoms (β=-1.13, 95% CI -1.99 to -0.26), self-identified problems (β=-1.56, 95% CI -2.54 to -0.59) and well-being (β=6.22, 95% CI 1.60 to 10.90)., Conclusions: Although SH+ did not differ significantly from ECAU in reducing symptoms of depression at postintervention, it did present benefits for particularly vulnerable participants (ie, unemployed and with lower mental well-being levels), and benefits were also evident at midterm follow-up. These results are promising for the use of SH+ in the management of depressive symptoms and improvement of well-being and self-identified problems among refugees and asylum seekers., Competing Interests: Competing interests: RGW acted as a consultant reviewer to the WHO in the development of the SH+ intervention, and I am an author on the papers reporting on the RCTs in the EU and Uganda. The rest of the authors have nothing to declare., (© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY. Published by BMJ.)
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- 2023
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