Search

Your search keyword '"Abu-Alfa, Ali K."' showing total 179 results
Start Over Author "Abu-Alfa, Ali K."
179 results on '"Abu-Alfa, Ali K."'

1. An update on the global disparities in kidney disease burden and care across world countries and regions

Author

Abu-Alfa, Ali K., Amouzegar, Atefeh, Anand, Shuchi, Arogundade, Fatiu Abiola, Ashuntantang, Gloria E., Bavanandan, Sunita, Coppo, Rosanna, Diongole, Hassane M., Divyaveer, Smita, Ekrikpo, Udeme E., Ethier, Isabelle, Fung, Winston Wing-Shing, Gaipov, Abduzhappar, Ghimire, Anukul, Houston, Ghenette, Ibrahim, Kwaifa Salihu, Irish, Georgina, Jindal, Kailash, Kelly, Dearbhla M., Lightstone, Liz, Madero, Magdalena, Nalado, Aisha M., Neuen, Brendon L., Olanrewaju, Timothy O., Osman, Mohamed A., Parekh, Rulan S., Petrova, Anna, Prasad, Narayan, Prikhodina, Larisa, Racki, Sanjin, Riaz, Parnian, Saad, Syed, Sakajiki, Aminu Muhammad, Savaj, Shokoufeh, Singh Shah, Dibya, Suzuki, Yusuke, Tesar, Vladimir, Tiv, Sophanny, Tungsanga, Somkanya, Tzanno-Martins, Carmen, Viecelli, Andrea, Wang, Angela Yee-Moon, Wong, Muh Geot, Zaidi, Deenaz, Bello, Aminu K, Okpechi, Ikechi G, Levin, Adeera, Ye, Feng, Damster, Sandrine, Arruebo, Silvia, Donner, Jo-Ann, Caskey, Fergus J, Cho, Yeoungjee, Davids, M Razeen, Davison, Sara N, Htay, Htay, Jha, Vivekanand, Lalji, Rowena, Malik, Charu, Nangaku, Masaomi, See, Emily, Sozio, Stephen M, Tonelli, Marcello, Wainstein, Marina, Yeung, Emily K, and Johnson, David W

Published
2024
Full Text
View/download PDF

3. Increasing access to integrated ESKD care as part of universal health coverage

Author

Harris, David CH, Davies, Simon J, Finkelstein, Fredric O, Jha, Vivekanand, Donner, Jo-Ann, Abraham, Georgi, Bello, Aminu K, Caskey, Fergus J, Garcia, Guillermo Garcia, Harden, Paul, Hemmelgarn, Brenda, Johnson, David W, Levin, Nathan W, Luyckx, Valerie A, Martin, Dominique E, McCulloch, Mignon I, Moosa, Mohammed Rafique, O’Connell, Philip J, Okpechi, Ikechi G, Filho, Roberto Pecoits, Shah, Kamal D, Sola, Laura, Swanepoel, Charles, Tonelli, Marcello, Twahir, Ahmed, van Biesen, Wim, Varghese, Cherian, Yang, Chih-Wei, Zuniga, Carlos, Summit, Working Groups of the International Society of Nephrology’s 2nd Global Kidney Health, Abu Alfa, Ali K, Aljubori, Harith M, Alrukhaimi, Mona N, Andreoli, Sharon P, Ashuntantang, Gloria, Bellorin-Font, Ezequiel, Bernieh, Bassam, Ibhais, Fuad M, Blake, Peter G, Brown, Mark, Brown, Edwina, Bunnag, Sakarn, Chan, Tak Mao, Chen, Yuqing, Granado, Rolando Claure-Del, Claus, Stefaan, Collins, Allan, Couchoud, Cecile, Cueto-Manzano, Alfonso, Cullis, Brett, Douthat, Walter, Dreyer, Gavin, Eiam-Ong, Somchai, Eke, Felicia U, Feehally, John, Ghnaimat, Mohammad A, Goh, BakLeong, Hassan, Mohamed H, Hou, Fan Fan, Jager, Kitty, Kalantar-Zadeh, Kamyar, Kazancioglu, Rumeyza T, Levin, Adeera, Liew, Adrian, McKnight, Marla, Mengistu, Yewondwassesn Tadesse, Morton, Rachael L, Muller, Elmi, Murtagh, Fliss EM, Naicker, Saraladevi, Nangaku, Masaomi, Niang, Abdou, Obrador, Gregorio T, Ossareh, Shahrzad, Perl, Jeffrey, Rahman, Muhibur, Rashid, Harun Ur, Richards, Marie, Rondeau, Eric, Sahay, Manisha, Saleh, Abdulkarim, Schneditz, Daniel, Tchokhonelidze, Irma, Tesar, Vladimir, Trask, Michele, Tungsanga, Kriang, Vachharajani, Tushar, Walker, Rachael C, Walker, Robert, Were, Anthony JO, Yao, Qiang, Yeates, Karen, Yu, Xueqing, Zakharova, Elena, Zemchenkov, Alexander, and Zhao, Ming-Hui

Subjects
Clinical Research, Health Services, Behavioral and Social Science, Kidney Disease, Health and social care services research, 8.1 Organisation and delivery of services, 8.3 Policy, ethics, and research governance, Good Health and Well Being, Quality Education, Conservative Treatment, Developing Countries, Global Burden of Disease, Global Health, Health Occupations, Health Planning, Health Policy, Health Services Accessibility, Health Workforce, Humans, Kidney Failure, Chronic, Patient Advocacy, Renal Replacement Therapy, Universal Health Insurance, advocacy, conservative care, dialysis, end-stage kidney disease, ESKD, funding, training, transplantation, universal health coverage, Working Groups of the International Society of Nephrology’s 2nd Global Kidney Health Summit, Clinical Sciences, Urology & Nephrology
Abstract

The global nephrology community recognizes the need for a cohesive strategy to address the growing problem of end-stage kidney disease (ESKD). In March 2018, the International Society of Nephrology hosted a summit on integrated ESKD care, including 92 individuals from around the globe with diverse expertise and professional backgrounds. The attendees were from 41 countries, including 16 participants from 11 low- and lower-middle-income countries. The purpose was to develop a strategic plan to improve worldwide access to integrated ESKD care, by identifying and prioritizing key activities across 8 themes: (i) estimates of ESKD burden and treatment coverage, (ii) advocacy, (iii) education and training/workforce, (iv) financing/funding models, (v) ethics, (vi) dialysis, (vii) transplantation, and (viii) conservative care. Action plans with prioritized lists of goals, activities, and key deliverables, and an overarching performance framework were developed for each theme. Examples of these key deliverables include improved data availability, integration of core registry measures and analysis to inform development of health care policy; a framework for advocacy; improved and continued stakeholder engagement; improved workforce training; equitable, efficient, and cost-effective funding models; greater understanding and greater application of ethical principles in practice and policy; definition and application of standards for safe and sustainable dialysis treatment and a set of measurable quality parameters; and integration of dialysis, transplantation, and comprehensive conservative care as ESKD treatment options within the context of overall health priorities. Intended users of the action plans include clinicians, patients and their families, scientists, industry partners, government decision makers, and advocacy organizations. Implementation of this integrated and comprehensive plan is intended to improve quality and access to care and thereby reduce serious health-related suffering of adults and children affected by ESKD worldwide.

Published
2019

5. Improving the prognosis of patients with severely decreased glomerular filtration rate (CKD G4+): conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Author

Eckardt, Kai-Uwe, Bansal, Nisha, Coresh, Josef, Evans, Marie, Grams, Morgan E, Herzog, Charles A, James, Matthew T, Heerspink, Hiddo JL, Pollock, Carol A, Stevens, Paul E, Tamura, Manjula Kurella, Tonelli, Marcello A, Wheeler, David C, Winkelmayer, Wolfgang C, Cheung, Michael, Hemmelgarn, Brenda R, Participants, Conference, Abu-Alfa, Ali K, Anand, Shuchi, Arici, Mustafa, Ballew, Shoshana H, Block, Geoffrey A, Burgos-Calderon, Rafael, Charytan, David M, Das-Gupta, Zofia, Dwyer, Jamie P, Fliser, Danilo, Froissart, Marc, Gill, John S, Griffith, Kathryn E, Harris, David C, Huffman, Kate, Inker, Lesley A, Jager, Kitty J, Jun, Min, Kalantar-Zadeh, Kamyar, Kasiske, Bertrand L, Kovesdy, Csaba P, Krane, Vera, Lamb, Edmund J, Lerma, Edgar V, Levey, Andrew S, Levin, Adeera, Mauro, Juan Carlos Julián, Nash, Danielle M, Navaneethan, Sankar D, O’Donoghue, Donal, Obrador, Gregorio T, Pecoits-Filho, Roberto, Robinson, Bruce M, Schäffner, Elke, Segev, Dorry L, Stengel, Bénédicte, Stenvinkel, Peter, Tangri, Navdeep, Tentori, Francesca, Tsukamoto, Yusuke, Turakhia, Mintu P, Vazquez, Miguel A, Wang, Angela Yee-Moon, and Williams, Amy W

Subjects
Heart Disease, Cardiovascular, Clinical Research, Kidney Disease, Management of diseases and conditions, 7.3 Management and decision making, Renal and urogenital, Good Health and Well Being, Clinical Decision-Making, Consensus, Evidence-Based Medicine, Glomerular Filtration Rate, Humans, Kidney, Nephrology, Prognosis, Renal Insufficiency, Chronic, Risk Factors, Severity of Illness Index, chronic kidney disease, kidney failure, prediction, prognosis, progression, supportive care, Conference Participants, Clinical Sciences, Urology & Nephrology
Abstract

Patients with severely decreased glomerular filtration rate (GFR) (i.e., chronic kidney disease [CKD] G4+) are at increased risk for kidney failure, cardiovascular disease (CVD) events (including heart failure), and death. However, little is known about the variability of outcomes and optimal therapeutic strategies, including initiation of kidney replacement therapy (KRT). Kidney Disease: Improving Global Outcomes (KDIGO) organized a Controversies Conference with an international expert group in December 2016 to address this gap in knowledge. In collaboration with the CKD Prognosis Consortium (CKD-PC) a global meta-analysis of cohort studies (n = 264,515 individuals with CKD G4+) was conducted to better understand the timing of clinical outcomes in patients with CKD G4+ and risk factors for different outcomes. The results confirmed the prognostic value of traditional CVD risk factors in individuals with severely decreased GFR, although the risk estimates vary for kidney and CVD outcomes. A 2- and 4-year model of the probability and timing of kidney failure requiring KRT was also developed. The implications of these findings for patient management were discussed in the context of published evidence under 4 key themes: management of CKD G4+, diagnostic and therapeutic challenges of heart failure, shared decision-making, and optimization of clinical trials in CKD G4+ patients. Participants concluded that variable prognosis of patients with advanced CKD mandates individualized, risk-based management, factoring in competing risks and patient preferences.

Published
2018

6. Controversies in optimal anemia management: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference

Author

Abu-Alfa, Ali K., Afsar, Baris, Pai, Amy Barton, Besarab, Anatole, Moore, Geraldine Biddle, Casadevall, Nicole, Cases, Aleix, de Francisco, Angel, Eckardt, Kai-Uwe, Fishbane, Steven, Fried, Linda F., Ganz, Tomas, Ginzburg, Yelena Z., Gómez, Rafael, Goodnough, Lawrence T., Hamano, Takayuki, Hanudel, Mark R., Hao, Chuan-Ming, Iseki, Kunitoshi, Ix, Joachim H., Johansen, Kirsten L., Ketteler, Markus, Kovesdy, Csaba P., Leaf, David E., Macdougall, Iain C., Massy, Ziad A., McMahon, Lawrence P., Minutolo, Roberto, Nakanishi, Takeshi, Nemeth, Elizabeta, Obrador, Gregorio T., Parfrey, Patrick S., Park, Hyeong-Cheon, Pecoits-Filho, Roberto, Robinson, Bruce M., Roger, Simon D., Shah, Yatrik M., Spinowitz, Bruce S., Tanaka, Tetsuhiro, Tsukamoto, Yusuke, Tungsanga, Kriang, Walther, Carl P., Yee-Moon Wang, Angela, Wolf, Myles, Babitt, Jodie L., Eisenga, Michele F., Haase, Volker H., Kshirsagar, Abhijit V., Levin, Adeera, Locatelli, Francesco, Małyszko, Jolanta, Swinkels, Dorine W., Tarng, Der-Cherng, Cheung, Michael, Jadoul, Michel, Winkelmayer, Wolfgang C., and Drüeke, Tilman B.

Published
2021
Full Text
View/download PDF

7. International Society of Nephrology Global Kidney Health Atlas: structures, organization, and services for the management of kidney failure in the Middle East

Author

Amouzegar, Atefeh, Abu-Alfa, Ali K., Alrukhaimi, Mona N., Bello, Aminu K., Ghnaimat, Mohammad A., Johnson, David W., Jha, Vivekanand, Harris, David C.H., Levin, Adeera, Tonelli, Marcello, Lunney, Meaghan, Saad, Syed, Khan, Maryam, Zaidi, Deenaz, Osman, Mohamed A., Ye, Feng, Okpechi, Ikechi G., and Ossareh, Shahrzad

Published
2021
Full Text
View/download PDF

8. KDIGO Controversies Conference on onco-nephrology: kidney disease in hematological malignancies and the burden of cancer after kidney transplantation

Author

Abu-Alfa, Ali K., Amer, Hatem, Beutel, Gernot, Chapman, Jeremy, Chen, Xiaohong, Chudek, Jerzy, Cosmai, Laura, Danesi, Romano, De Stefano, Filippo, Iseki, Kunitoshi, Jaimes, Edgar A., Jhaveri, Kenar D., Jurczyszyn, Artur, Kazancioğlu, Rümeyza, Kitchlu, Abhijat, Kollmannsberger, Christian, Lahoti, Amit, Li, Yang, Macía, Manuel, Matsubara, Takeshi, Mitropoulos, Dionysios, Noiri, Eisei, Perazella, Mark A., Ronco, Pierre, Rosner, Mitchell H., Soler Romeo, Maria Jose, Sprangers, Ben, Stadler, Walter M., Stevens, Paul E., Tesař, Vladimír, Torres da Costa e Silva, Verônica, Vesole, David H., Vijayan, Anitha, Viklický, Ondřej, Workeneh, Biruh T., Yanagita, Motoko, Zakharova, Elena, Małyszko, Jolanta, Bamias, Aristotelis, Danesh, Farhad R., Dębska-Ślizień, Alicja, Gallieni, Maurizio, Gertz, Morie A., Kielstein, Jan T., Tesarova, Petra, Wong, Germaine, Cheung, Michael, Wheeler, David C., Winkelmayer, Wolfgang C., and Porta, Camillo

Published
2020
Full Text
View/download PDF

9. KDIGO Controversies Conference on onco-nephrology: understanding kidney impairment and solid-organ malignancies, and managing kidney cancer

Author

Abu-Alfa, Ali K., Amer, Hatem, Beutel, Gernot, Chapman, Jeremy, Chen, Xiaohong, Chudek, Jerzy, Cosmai, Laura, Danesi, Romano, De Stefano, Filippo, Iseki, Kunitoshi, Jaimes, Edgar A., Jhaveri, Kenar D., Jurczyszyn, Artur, Kazancioğlu, Rümeyza, Kitchlu, Abhijat, Kollmannsberger, Christian, Lahoti, Amit, Li, Yang, Macía, Manuel, Matsubara, Takeshi, Mitropoulos, Dionysios, Noiri, Eisei, Perazella, Mark A., Ronco, Pierre, Rosner, Mitchell H., Soler Romeo, Maria Jose, Sprangers, Ben, Stadler, Walter M., Stevens, Paul E., ladimír Tesař, Torres da Costa e Silva, Verônica, Vesole, David H., Vijayan, Anitha, Viklický, Ondřej, Workeneh, Biruh T., Yanagita, Motoko, Zakharova, Elena, Porta, Camillo, Bamias, Aristotelis, Danesh, Farhad R., Dębska-Ślizień, Alicja, Gallieni, Maurizio, Gertz, Morie A., Kielstein, Jan T., Tesarova, Petra, Wong, Germaine, Cheung, Michael, Wheeler, David C., Winkelmayer, Wolfgang C., and Małyszko, Jolanta

Published
2020
Full Text
View/download PDF

10. Strategic plan for integrated care of patients with kidney failure

Author

Abu Alfa, Ali K., Ashuntantang, Gloria, Brown, Edwina, Cullis, Brett, Dreyer, Gavin, Eke, Felicia U., Garcia, Guillermo Garcia, Goh, Bak Leong, Hemmelgarn, Brenda, Hou, Fan Fan, Iyengar, Arpana, Johnson, David W., Levin, Nathan W., Luyckx, Valerie A., Martin, Dominique E., McCulloch, Mignon I., Mengistu, Yewondwossesn Tadesse, Moosa, Mohammed Rafique, Morton, Rachael L., Niang, Abdou, Obrador, Gregorio T., Okpechi, Ikechi G., Ossareh, Shahrzad, Shah, Kamal D., Sola, Laura, Swanepoel, Charles, Tchokhonelidze, Irma, Tonelli, Marcello, Trask, Michele, Kazancioglu, Rumeyza Turan, Twahir, Ahmed, Walker, Robert, Were, Anthony J.O., Yang, Chih-Wei, Yeates, Karen, Zakharova, Elena, Zuniga, Carlos, Harris, David C.H., Davies, Simon J., Finkelstein, Fredric O., Jha, Vivekanand, Bello, Aminu K., Brown, Mark, Caskey, Fergus J., Donner, Jo-Ann, Liew, Adrian, Muller, Elmi, Naicker, Saraladevi, O’Connell, Philip J., Filho, Roberto Pecoits, and Vachharajani, Tushar

Published
2020
Full Text
View/download PDF

11. Considerations on equity in management of end-stage kidney disease in low- and middle-income countries

Author

Van Biesen, Wim, Jha, Vivekanand, Abu-Alfa, Ali K., Andreoli, Sharon P., Ashuntantang, Gloria, Bernieh, Bassam, Brown, Edwina, Chen, Yuqing, Coppo, Rosanna, Couchoud, Cecile, Cullis, Brett, Douthat, Walter, Eke, Felicia U., Hemmelgarn, Brenda, Hou, Fan Fan, Levin, Nathan W., Luyckx, Valerie A., Morton, Rachael L., Moosa, Mohammed Rafique, Murtagh, Fliss E.M., Richards, Marie, Rondeau, Eric, Schneditz, Daniel, Shah, Kamal D., Tesar, Vladimir, Yeates, Karen, and Garcia Garcia, Guillermo

Published
2020
Full Text
View/download PDF

13. Dialysis initiation, modality choice, access, and prescription: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Author

Abu-Alfa, Ali K., Bargman, Joanne M., Bleyer, Anthony J., Brown, Edwina A., Davenport, Andrew, Davies, Simon J., Finkelstein, Frederic O., Flythe, Jennifer E., Goffin, Eric, Golper, Thomas A., Gómez, Rafael, Hamano, Takayuki, Hecking, Manfred, Heimbürger, Olof, Hole, Barnaby, Hothi, Daljit K., Ikizler, T. Alp, Isaka, Yoshitaka, Iseki, Kunitoshi, Jha, Vivekanand, Kawanishi, Hideki, Kerr, Peter G., Komenda, Paul, Kovesdy, Csaba P., Lacson, Ed, Jr., Laville, Maurice, Lee, Jung Pyo, Lerma, Edgar V., Levin, Nathan W., Lichodziejewska-Niemierko, Monika, Liew, Adrian, Lindley, Elizabeth, Lockridge, Robert S., Madero, Magdalena, Massy, Ziad A., McCann, Linda, Meyer, Klemens B., Morton, Rachael L., Nadeau-Fredette, Annie-Claire, Okada, Hirokazu, Perez, Jose, Perl, Jeff, Polkinghorne, Kevan R., Riella, Miguel C., Robinson, Bruce M., Rocco, Michael V., Rosansky, Steven J., Rotmans, Joris I., Fernanda Slon Roblero, María, Tangri, Navdeep, Tonelli, Marcello, Tong, Allison, Tsukamoto, Yusuke, Tungsanga, Kriang, Vachharajani, Tushar J., van Loon, Ismay, Watnick, Suzanne, Weiner, Daniel E., Wilkie, Martin, Zakharova, Elena, Chan, Christopher T., Blankestijn, Peter J., Dember, Laura M., Gallieni, Maurizio, Harris, David C.H., Lok, Charmaine E., Mehrotra, Rajnish, Stevens, Paul E., Wang, Angela Yee-Moon, Cheung, Michael, Wheeler, David C., Winkelmayer, Wolfgang C., and Pollock, Carol A.

Published
2019
Full Text
View/download PDF

14. Heart failure in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Author

Abu-Alfa, Ali K., Amann, Kerstin, Aonuma, Kazutaka, Appel, Lawrence J., Baigent, Colin, Bakris, George L., Banerjee, Debasish, Boletis, John N., Bozkurt, Biykem, Butler, Javed, Chan, Christopher T., Costanzo, Maria Rosa, Dubin, Ruth F., Filippatos, Gerasimos, Gikonyo, Betty M., Gikonyo, Dan K., Hajjar, Roger J., Iseki, Kunitoshi, Ishii, Hideki, Knoll, Greg A., Lenihan, Colin R., Lentine, Krista L., Lerma, Edgar V., Macedo, Etienne, Mark, Patrick B., Noiri, Eisei, Palazzuoli, Alberto, Pecoits-Filho, Roberto, Pitt, Bertram, Rigatto, Claudio, Rossignol, Patrick, Setoguchi, Soko, Sood, Manish M., Störk, Stefan, Suri, Rita S., Szummer, Karolina, Tang, Sydney C.W., Tangri, Navdeep, Thompson, Aliza, Vijayaraghavan, Krishnaswami, Walsh, Michael, Wang, Angela Yee-Moon, Weir, Matthew R., House, Andrew A., Wanner, Christoph, Sarnak, Mark J., Piña, Ileana L., McIntyre, Christopher W., Komenda, Paul, Kasiske, Bertram L., Deswal, Anita, deFilippi, Christopher R., Cleland, John G.F., Anker, Stefan D., Herzog, Charles A., Cheung, Michael, Wheeler, David C., Winkelmayer, Wolfgang C., and McCullough, Peter A.

Published
2019
Full Text
View/download PDF

15. Increasing access to integrated ESKD care as part of universal health coverage

Author

Abu Alfa, Ali K., Aljubori, Harith M., Alrukhaimi, Mona N., Andreoli, Sharon P., Ashuntantang, Gloria, Bellorin-Font, Ezequiel, Bernieh, Bassam, Ibhais, Fuad M., Blake, Peter G., Brown, Mark, Brown, Edwina, Bunnag, Sakarn, Chan, Tak Mao, Chen, Yuqing, Claure-Del Granado, Rolando, Claus, Stefaan, Collins, Allan, Couchoud, Cecile, Cueto-Manzano, Alfonso, Cullis, Brett, Douthat, Walter, Dreyer, Gavin, Eiam-Ong, Somchai, Eke, Felicia U., Feehally, John, Ghnaimat, Mohammad A., Goh, BakLeong, Hassan, Mohamed H., Hou, Fan Fan, Jager, Kitty, Kalantar-Zadeh, Kamyar, Kazancioglu, Rumeyza T., Levin, Adeera, Liew, Adrian, McKnight, Marla, Mengistu, Yewondwassesn Tadesse, Morton, Rachael L., Muller, Elmi, Murtagh, Fliss E.M., Naicker, Saraladevi, Nangaku, Masaomi, Niang, Abdou, Obrador, Gregorio T., Ossareh, Shahrzad, Perl, Jeffrey, Rahman, Muhibur, Rashid, Harun Ur, Richards, Marie, Rondeau, Eric, Sahay, Manisha, Saleh, Abdulkarim, Schneditz, Daniel, Tchokhonelidze, Irma, Tesar, Vladimir, Trask, Michele, Tungsanga, Kriang, Vachharajani, Tushar, Walker, Rachael C., Walker, Robert, Were, Anthony J.O., Yao, Qiang, Yeates, Karen, Yu, Xueqing, Zakharova, Elena, Zemchenkov, Alexander, Zhao, Ming-Hui, Harris, David C.H., Davies, Simon J., Finkelstein, Fredric O., Jha, Vivekanand, Donner, Jo-Ann, Abraham, Georgi, Bello, Aminu K., Caskey, Fergus J., Garcia, Guillermo Garcia, Harden, Paul, Hemmelgarn, Brenda, Johnson, David W., Levin, Nathan W., Luyckx, Valerie A., Martin, Dominique E., McCulloch, Mignon I., Moosa, Mohammed Rafique, O’Connell, Philip J., Okpechi, Ikechi G., Pecoits Filho, Roberto, Shah, Kamal D., Sola, Laura, Swanepoel, Charles, Tonelli, Marcello, Twahir, Ahmed, van Biesen, Wim, Varghese, Cherian, Yang, Chih-Wei, and Zuniga, Carlos

Published
2019
Full Text
View/download PDF

16. Improving the prognosis of patients with severely decreased glomerular filtration rate (CKD G4+): conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Author

Abu-Alfa, Ali K., Anand, Shuchi, Arici, Mustafa, Ballew, Shoshana H., Block, Geoffrey A., Burgos-Calderon, Rafael, Charytan, David M., Das-Gupta, Zofia, Dwyer, Jamie P., Fliser, Danilo, Froissart, Marc, Gill, John S., Griffith, Kathryn E., Harris, David C., Huffman, Kate, Inker, Lesley A., Jager, Kitty J., Jun, Min, Kalantar-Zadeh, Kamyar, Kasiske, Bertrand L., Kovesdy, Csaba P., Krane, Vera, Lamb, Edmund J., Lerma, Edgar V., Levey, Andrew S., Levin, Adeera, Julián Mauro, Juan Carlos, Nash, Danielle M., Navaneethan, Sankar D., O’Donoghue, Donal, Obrador, Gregorio T., Pecoits-Filho, Roberto, Robinson, Bruce M., Schäffner, Elke, Segev, Dorry L., Stengel, Bénédicte, Stenvinkel, Peter, Tangri, Navdeep, Tentori, Francesca, Tsukamoto, Yusuke, Turakhia, Mintu P., Vazquez, Miguel A., Yee-Moon Wang, Angela, Williams, Amy W., Eckardt, Kai-Uwe, Bansal, Nisha, Coresh, Josef, Evans, Marie, Grams, Morgan E., Herzog, Charles A., James, Matthew T., Heerspink, Hiddo J.L., Pollock, Carol A., Stevens, Paul E., Tamura, Manjula Kurella, Tonelli, Marcello A., Wheeler, David C., Winkelmayer, Wolfgang C., Cheung, Michael, and Hemmelgarn, Brenda R.

Published
2018
Full Text
View/download PDF

18. Capacity for the management of kidney failure in the International Society of Nephrology Middle East region: report from the 2023 ISN Global Kidney Health Atlas (ISN-GKHA)

Author

Karam, Sabine, Amouzegar, Atefeh, Alshamsi, Iman Rashed, Al Ghamdi, Saeed M.G., Anwar, Siddiq, Ghnaimat, Mohammad, Saeed, Bassam, Arruebo, Silvia, Bello, Aminu K., Caskey, Fergus J., Damster, Sandrine, Donner, Jo-Ann, Jha, Vivekanand, Johnson, David W., Levin, Adeera, Malik, Charu, Nangaku, Masaomi, Okpechi, Ikechi G., Tonelli, Marcello, Ye, Feng, Abu-Alfa, Ali K., Savaj, Shokoufeh, Abou-Jaoudeh, Pauline, Al Hussain, Turki, Al Salmi, Issa Salim Amur, Alrukhaimi, Mona, Alyousef, Anas, Bahous, Sola Aoun, Cai, Guangyan, Cheikh Hassan, Hicham I., Cho, Yeoungjee, Davids, M. Razeen, Davison, Sara N., Diongole, Hassane M., Divyaveer, Smita, Ekrikpo, Udeme E., Ethier, Isabelle, Fung, Winston Wing-Shing, Ghimire, Anukul, Hooman, Nakysa, Houston, Ghenette, Htay, Htay, Ibrahim, Kwaifa Salihu, Irish, Georgina, Jindal, Kailash, Kelly, Dearbhla M., Lalji, Rowena, Mitwali, Ahmed, Mortazavi, Mojgan, Nalado, Aisha M., Neuen, Brendon L., Olanrewaju, Timothy O., Osman, Mohamed A., Ossareh, Shahrzad, Petrova, Anna, Riaz, Parnian, Saad, Syed, Sakajiki, Aminu Muhammad, See, Emily, Sozio, Stephen M., Tiv, Sophanny, Tungsanga, Somkanya, Viecelli, Andrea, Wainstein, Marina, Wannous, Hala, Yeung, Emily K., and Zaidi, Deenaz

Abstract

The highest financial and symptom burdens and the lowest health-related quality-of-life scores are seen in people with kidney failure. A total of 11 countries in the International Society of Nephrology (ISN) Middle East region responded to the ISN-Global Kidney Health Atlas. The prevalence of chronic kidney disease (CKD) in the region ranged from 4.9% in Yemen to 12.2% in Lebanon, whereas prevalence of kidney failure treated with dialysis or transplantation ranged from 152 per million population (pmp) in the United Arab Emirates to 869 pmp in Kuwait. Overall, the incidence of kidney transplantation was highest in Saudi Arabia (20.2 pmp) and was lowest in Oman (2.2 pmp). Chronic hemodialysis (HD) and peritoneal dialysis (PD) services were available in all countries, whereas kidney transplantation was available in most countries of the region. Public government funding that makes acute dialysis, chronic HD, chronic PD, and kidney transplantation medications free at the point of delivery was available in 54.5%, 72.7%, 54.5%, and 54.5% of countries, respectively. Conservative kidney management was available in 45% of countries. Only Oman had a CKD registry; 7 countries (64%) had dialysis registries, and 8 (73%) had kidney transplantation registries. The ISN Middle East region has a high burden of kidney disease and multiple challenges to overcome. Prevention and detection of kidney disease can be improved by the design of tailored guidelines, allocation of additional resources, improvement of early detection at all levels of care, and implementation of sustainable health information systems.

Published
2024
Full Text
View/download PDF

19. Impact of Sodium-Glucose Cotransporter-2 Inhibitors in the Management of Chronic Kidney Disease: A Middle East and Africa Perspective.

Author

Elkeraie, Ahmed Fathi, Al-Ghamdi, Saeed, Abu-Alfa, Ali K, Alotaibi, Torki, AlSaedi, Ali Jasim, AlSuwaida, Abdulkareem, Arici, Mustafa, Ecder, Tevfik, Ghnaimat, Mohammad, Hafez, Mohamed Hany, Hassan, Mohamed H, and Sqalli, Tarik

Subjects
CHRONIC kidney failure, SODIUM-glucose cotransporters, TYPE 2 diabetes, ALDOSTERONE antagonists, RENIN-angiotensin system
Abstract

Chronic kidney disease (CKD) is a major public health concern in the Middle East and Africa (MEA) region and a leading cause of death in patients with type 2 diabetes mellitus (T2DM) and hypertension. Early initiation of sodium-glucose cotransporter - 2 inhibitors (SGLT-2i) and proper sequencing with renin-angiotensin-aldosterone system inhibitors (RAASi) in these patients may result in better clinical outcomes due to their cardioprotective properties and complementary mechanisms of action. In this review, we present guideline-based consensus recommendations by experts from the MEA region, as practical algorithms for screening, early detection, nephrology referral, and treatment pathways for CKD management in patients with hypertension and diabetes mellitus. This study will help physicians take timely and appropriate actions to provide better care to patients with CKD or those at high risk of CKD. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

26. Controversies in Optimal Anemia Management : Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference

Author

Babitt, Jodie L., Eisenga, Michele F., Haase, Volker H., Kshirsagar, Abhijit V., Levin, Adeera I., Locatelli, Francesco, Małyszko, Jolanta, Swinkels, Dorine W., Tarng, Der Cherng, Cheung, Michael, Jadoul, Michel y., Winkelmayer, Wolfgang C., Drüeke, Tilman Bernhard, Abu-Alfa, Ali K., Afsar, Bariş, Pai, Amy Barton, Besarab, Anatole, Moore, Geraldine Biddle, Casadevall, Nicole, Cases, Aleix, de Francisco, Ángel Luís Martín, Eckardt, Kai Uwe, Fishbane, Steven N., Fried, Linda F., Ganz, Tomas, Ginzburg, yelena Z., Gómez, Rafael, Goodnough, Lawrence Tim, Hamano, Takayuki, Hanudel, Mark R., Hao, Chuanming, Iseki, Kunitoshi, Ix, Joachim H., Johansen, Kirsten L., Ketteler, Markus, Kovesdy, Csaba P., Leaf, David E., Macdougall, Iain C., Massy, Ziad André, Mcmahon, Lawrence P., Minutolo, Roberto, Nakanishi, Takeshi, Nemeth, Elizabeta, Obrador, Gregorio T., Parfrey, Patrick S., Park, Hyeong-Cheon, Pecoits-Filho, Roberto, Robinson, Bruce M., Roger, Simon D., Shah, yatrik M., Spinowitz, Bruce S., Tanaka, Tetsuhiro, Tsukamoto, yusuke, Tungsanga, Kriang, Walther, Carl P., yee-Moon Wang, Angela yee Moon, Wolf, Myles, Babitt, Jodie, Eisenga, Michele, Haase, Volker, Kshirsagar, Abhijit, Levin, Adeera, Swinkels, Dorine, Tarng, Der-Cherng, Jadoul, Michel, Winkelmayer, Wolfgang, Dru ¨eke, Tilman, Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Hôpital Paul Brousse, National Institutes of Health, NIH: RO1-DK087727 Boehringer Ingelheim, BI Amgen Astellas Pharma US AstraZeneca Massachusetts General Hospital, MGH FibroGen AMAG Pharmaceuticals, This conference was sponsored by KDIGO and supported in part by unrestricted educational grants from Akebia Therapeutics, AMAG Pharmaceuticals , Amgen , Astellas, AstraZeneca , Boehringer Ingelheim, FibroGen , GlaxoSmithKline , Mitsubishi Tanabe Pharma Group, Pharmacosmos, Roche , Rockwell Medical, Torii Pharmaceutical, and Vifor Fresenius Medical Care Renal Pharma., JLB has declared receiving consulting fees from Disc Medicine and Incyte Corporation, equity ownership from Ferrumax Pharmaceuticals, research support from the National Institutes of Health (grant RO1-DK087727) and the Patricia and Scott Eston Massachusetts General Hospital Research Scholar Award, and patent royalties for intellectual property owned by Massachusetts General Hospital that is licensed to Ferrumax Pharmaceuticals on BMP and HJV targeted therapies for iron disorders. MFE has declared receiving consultant fees from Vifor Pharma, serving on the Advisory Board for Cablon Medical, and receiving speakers bureaus from Vifor Pharma. VHH has declared receiving consultant fees from Akebia Therapeutics, AstraZeneca, FibroGen, Incyte Corporation, and Rockwell Medical. AVK has declared receiving consultant fees from Rockwell Medical. AL has declared receiving consultant fees from AstraZeneca and research support from AstraZeneca. FL has declared receiving consultant fees from Amgen and AstraZeneca, and speakers bureaus from Amgen, AstraZeneca, and Roche. JM has declared receiving consultant fees from AstraZeneca and speakers bureaus from Bayer Healthcare. DWS has declared receiving consultant fees from Silence Therapeutics. MJ has declared receiving consultant fees from Astellas, AstraZeneca, Boehringer Ingelheim, Fresenius Medical Care Asia Pacific, Mundipharma, and Vifor Fresenius Medical Care, serving on speakers bureaus from Astellas, AstraZeneca, Mundipharma, and Vifor Fresenius Medical Care, and receiving research support from Amgen and future research support from AstraZeneca. WCW has declared receiving consultant fees from Akebia/Otsuka, AstraZeneca, Bayer Healthcare, Janssen, Merck, Reata, and Relypsa, future consultant fees from Boehringer Ingelheim, and research support from the National Institutes of Health. TBD has declared receiving consultancy fees from Astellas, GlaxoSmithKline, and KfH Stiftung, and future consultant fees from Astellas. All the other authors declared no competing interests., Babitt, J. L., Eisenga, M. F., Haase, V. H., Kshirsagar, A. V., Levin, A., Locatelli, F., Malyszko, J., Swinkels, D. W., Tarng, D. -C., Cheung, M., Jadoul, M., Winkelmayer, W. C., Drueke, T. B., Abu-Alfa, A. K., Afsar, B., Pai, A. B., Besarab, A., Moore, G. B., Casadevall, N., Cases, A., de Francisco, A., Eckardt, K. -U., Fishbane, S., Fried, L. F., Ganz, T., Ginzburg, Y. Z., Gomez, R., Goodnough, L. T., Hamano, T., Hanudel, M. R., Hao, C. -M., Iseki, K., Ix, J. H., Johansen, K. L., Ketteler, M., Kovesdy, C. P., Leaf, D. E., Macdougall, I. C., Massy, Z. A., Mcmahon, L. P., Minutolo, R., Nakanishi, T., Nemeth, E., Obrador, G. T., Parfrey, P. S., Park, H. -C., Pecoits-Filho, R., Robinson, B. M., Roger, S. D., Shah, Y. M., Spinowitz, B. S., Tanaka, T., Tsukamoto, Y., Tungsanga, K., Walther, C. P., Yee-Moon Wang, A., Wolf, M., UCL - SSS/IREC/NEFR - Pôle de Néphrologie, and UCL - (SLuc) Service de néphrologie

Subjects
0301 basic medicine, medicine.medical_specialty, dialysi, Anemia, medicine.medical_treatment, [SDV]Life Sciences [q-bio], 030232 urology & nephrology, law.invention, 03 medical and health sciences, 0302 clinical medicine, Prolyl-Hydroxylase Inhibitor, iron, iron deficiency, Randomized controlled trial, Hematinic, law, Basic research, erythropoiesis stimulating agent, Epidemiology, Urologi och njurmedicin, medicine, Humans, Urology and Nephrology, Renal Insufficiency, Chronic, Intensive care medicine, Dialysis, business.industry, Prolyl-Hydroxylase Inhibitors, Guideline, medicine.disease, Anemia management, anemia, 3. Good health, erythropoiesis stimulating agents, 030104 developmental biology, Nephrology, Hematinics, dialysis, erythropoietin, hepcidin, hypoxia-inducible factor-prolyl hydroxylase inhibitor, business, chronic kidney disease, Kidney disease, Human
Abstract

International audience; In chronic kidney disease, anemia and disordered iron homeostasis are prevalent and associated with significant adverse consequences. In 2012, Kidney Disease: Improving Global Outcomes (KDIGO) issued an anemia guideline for managing the diagnosis, evaluation, and treatment of anemia in chronic kidney disease. Since then, new data have accrued from basic research, epidemiological studies, and randomized trials that warrant a re-examination of previous recommendations. Therefore, in 2019, KDIGO decided to convene 2 Controversies Conferences to review the latest evidence, explore new and ongoing controversies, assess change implications for the current KDIGO anemia guideline, and propose a research agenda. The first conference, described here, focused mainly on iron-related issues, including the contribution of disordered iron homeostasis to the anemia of chronic kidney disease, diagnostic challenges, available and emerging iron therapies, treatment targets, and patient outcomes. The second conference will discuss issues more specifically related to erythropoiesis-stimulating agents, including epoetins, and hypoxia-inducible factor-prolyl hydroxylase inhibitors. Here we provide a concise overview of the consensus points and controversies resulting from the first conference and prioritize key questions that need to be answered by future research.

Published
2021
Full Text
View/download PDF

27. Controversies in optimal anemia management: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference

Author

Babitt, Jodie L., primary, Eisenga, Michele F., additional, Haase, Volker H., additional, Kshirsagar, Abhijit V., additional, Levin, Adeera, additional, Locatelli, Francesco, additional, Małyszko, Jolanta, additional, Swinkels, Dorine W., additional, Tarng, Der-Cherng, additional, Cheung, Michael, additional, Jadoul, Michel, additional, Winkelmayer, Wolfgang C., additional, Drüeke, Tilman B., additional, Abu-Alfa, Ali K., additional, Afsar, Baris, additional, Pai, Amy Barton, additional, Besarab, Anatole, additional, Moore, Geraldine Biddle, additional, Casadevall, Nicole, additional, Cases, Aleix, additional, de Francisco, Angel, additional, Eckardt, Kai-Uwe, additional, Fishbane, Steven, additional, Fried, Linda F., additional, Ganz, Tomas, additional, Ginzburg, Yelena Z., additional, Gómez, Rafael, additional, Goodnough, Lawrence T., additional, Hamano, Takayuki, additional, Hanudel, Mark R., additional, Hao, Chuan-Ming, additional, Iseki, Kunitoshi, additional, Ix, Joachim H., additional, Johansen, Kirsten L., additional, Ketteler, Markus, additional, Kovesdy, Csaba P., additional, Leaf, David E., additional, Macdougall, Iain C., additional, Massy, Ziad A., additional, McMahon, Lawrence P., additional, Minutolo, Roberto, additional, Nakanishi, Takeshi, additional, Nemeth, Elizabeta, additional, Obrador, Gregorio T., additional, Parfrey, Patrick S., additional, Park, Hyeong-Cheon, additional, Pecoits-Filho, Roberto, additional, Robinson, Bruce M., additional, Roger, Simon D., additional, Shah, Yatrik M., additional, Spinowitz, Bruce S., additional, Tanaka, Tetsuhiro, additional, Tsukamoto, Yusuke, additional, Tungsanga, Kriang, additional, Walther, Carl P., additional, Yee-Moon Wang, Angela, additional, and Wolf, Myles, additional

Published
2021
Full Text
View/download PDF

32. Corrigendum to “Tonelli M, Nkunu V, Varghese C, et al. Framework for establishing integrated kidney care programs in low- and middle-income countries” Kidney Int Suppl. 2020;10:e19–e23

Author

Tonelli, Marcello, primary, Nkunu, Victoria, additional, Varghese, Cherian, additional, Abu-Alfa, Ali K., additional, Alrukhaimi, Mona N., additional, Bernieh, Bassam, additional, Fox, Louise, additional, Gill, John, additional, Harris, David C.H., additional, Hou, Fan Fan, additional, O’Connell, Philip J., additional, Rashid, Harun Ur, additional, Niang, Abdou, additional, Ossareh, Shahrzad, additional, Tesar, Vladimir, additional, Zakharova, Elena, additional, and Yang, Chih-Wei, additional

Published
2020
Full Text
View/download PDF

33. KDIGO Controversies Conference on onco-nephrology: kidney disease in hematological malignancies and the burden of cancer after kidney transplantation

Author

Małyszko, Jolanta, primary, Bamias, Aristotelis, additional, Danesh, Farhad R., additional, Dębska-Ślizień, Alicja, additional, Gallieni, Maurizio, additional, Gertz, Morie A., additional, Kielstein, Jan T., additional, Tesarova, Petra, additional, Wong, Germaine, additional, Cheung, Michael, additional, Wheeler, David C., additional, Winkelmayer, Wolfgang C., additional, Porta, Camillo, additional, Abu-Alfa, Ali K., additional, Amer, Hatem, additional, Beutel, Gernot, additional, Chapman, Jeremy, additional, Chen, Xiaohong, additional, Chudek, Jerzy, additional, Cosmai, Laura, additional, Danesi, Romano, additional, De Stefano, Filippo, additional, Iseki, Kunitoshi, additional, Jaimes, Edgar A., additional, Jhaveri, Kenar D., additional, Jurczyszyn, Artur, additional, Kazancioğlu, Rümeyza, additional, Kitchlu, Abhijat, additional, Kollmannsberger, Christian, additional, Lahoti, Amit, additional, Li, Yang, additional, Macía, Manuel, additional, Matsubara, Takeshi, additional, Mitropoulos, Dionysios, additional, Noiri, Eisei, additional, Perazella, Mark A., additional, Ronco, Pierre, additional, Rosner, Mitchell H., additional, Soler Romeo, Maria Jose, additional, Sprangers, Ben, additional, Stadler, Walter M., additional, Stevens, Paul E., additional, Tesař, Vladimír, additional, Torres da Costa e Silva, Verônica, additional, Vesole, David H., additional, Vijayan, Anitha, additional, Viklický, Ondřej, additional, Workeneh, Biruh T., additional, Yanagita, Motoko, additional, and Zakharova, Elena, additional

Published
2020
Full Text
View/download PDF

34. Strategic plan for integrated care of patients with kidney failure

Author

Harris, David C.H., primary, Davies, Simon J., additional, Finkelstein, Fredric O., additional, Jha, Vivekanand, additional, Bello, Aminu K., additional, Brown, Mark, additional, Caskey, Fergus J., additional, Donner, Jo-Ann, additional, Liew, Adrian, additional, Muller, Elmi, additional, Naicker, Saraladevi, additional, O’Connell, Philip J., additional, Filho, Roberto Pecoits, additional, Vachharajani, Tushar, additional, Abu Alfa, Ali K., additional, Ashuntantang, Gloria, additional, Brown, Edwina, additional, Cullis, Brett, additional, Dreyer, Gavin, additional, Eke, Felicia U., additional, Garcia, Guillermo Garcia, additional, Goh, Bak Leong, additional, Hemmelgarn, Brenda, additional, Hou, Fan Fan, additional, Iyengar, Arpana, additional, Johnson, David W., additional, Levin, Nathan W., additional, Luyckx, Valerie A., additional, Martin, Dominique E., additional, McCulloch, Mignon I., additional, Mengistu, Yewondwossesn Tadesse, additional, Moosa, Mohammed Rafique, additional, Morton, Rachael L., additional, Niang, Abdou, additional, Obrador, Gregorio T., additional, Okpechi, Ikechi G., additional, Ossareh, Shahrzad, additional, Shah, Kamal D., additional, Sola, Laura, additional, Swanepoel, Charles, additional, Tchokhonelidze, Irma, additional, Tonelli, Marcello, additional, Trask, Michele, additional, Kazancioglu, Rumeyza Turan, additional, Twahir, Ahmed, additional, Walker, Robert, additional, Were, Anthony J.O., additional, Yang, Chih-Wei, additional, Yeates, Karen, additional, Zakharova, Elena, additional, and Zuniga, Carlos, additional

Published
2020
Full Text
View/download PDF

39. Heart failure in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies conference

Author

House, Andrew A., Wanner, Christoph, Sarnak, Mark J., Piña, Ileana L., McIntyre, Christopher W., Komenda, Paul, Kasiske, Bertram L., Deswal, Anita, deFilippi, Christopher R., Cleland, John G.F., Anker, Stefan D., Herzog, Charles A., Cheung, Michael, Wheeler, David C., Winkelmayer, Wolfgang C., McCullough, Peter A., Abu-Alfa, Ali K., Amann, Kerstin, Aonuma, Kazutaka, Appel, Lawrence J., Baigent, Colin, Bakris, George L., Banerjee, Debasish, Boletis, John N., Bozkurt, Biykem, Butler, Javed, Chan, Christopher T., Costanzo, Maria Rosa, Dubin, Ruth F., Filippatos, Gerasimos, Gikonyo, Betty M., Gikonyo, Dan K., Hajjar, Roger J., Iseki, Kunitoshi, Ishii, Hideki, Knoll, Greg A., Lenihan, Colin R., Lentine, Krista L., Lerma, Edgar V., Macedo, Etienne, Mark, Patrick B., Noiri, Eisei, Palazzuoli, Alberto, Pecoits-Filho, Roberto, Pitt, Bertram, Rigatto, Claudio, Rossignol, Patrick, Setoguchi, Soko, Sood, Manish M., Störk, Stefan, Suri, Rita S., Szummer, Karolina, Tang, Sydney C.W., Tangri, Navdeep, Thompson, Aliza, Vijayaraghavan, Krishnaswami, Walsh, Michael, Wang, Angela Yee-Moon, and Weir, Matthew R.

Subjects
urologic and male genital diseases, R1, female genital diseases and pregnancy complications
Abstract

The incidence and prevalence of heart failure (HF) and chronic kidney disease (CKD) are increasing, and as such a better understanding of the interface between both conditions is imperative for developing optimal strategies for their detection, prevention, diagnosis, and management. To this end, Kidney Disease: Improving Global Outcomes (KDIGO) convened an international, multidisciplinary Controversies Conference titled Heart Failure in CKD. Breakout group discussions included (i) HF with preserved ejection fraction (HFpEF) and nondialysis CKD, (ii) HF with reduced ejection fraction (HFrEF) and nondialysis CKD, (iii) HFpEF and dialysis-dependent CKD, (iv) HFrEF and dialysis-dependent CKD, and (v) HF in kidney transplant patients. The questions that formed the basis of discussions are available on the KDIGO website http://kdigo.org/conferences/heart-failure-in-ckd/, and the deliberations from the conference are summarized here.

Published
2019

40. Increasing access to integrated ESKD care as part of universal health coverage

Author

Harris, David C. H., DAVIES, Simon J., Finkelstein, Fredric O., JHA, Vivekanand, DONNER, Jo-Ann, ABRAHAM, Georgi, Bello, Aminu K., CASKEY, Fergus J., GARCIA GARCIA, Guillermo, HARDEN, Paul, KAZANCIOĞLU, RÜMEYZA TURAN, Hemmelgarn, Brenda, JOHNSON, David W., LEVIN, Nathan W., Luyckx, Valerie A., MARTIN, Dominique E., McCulloch, Mignon I., MOOSA, Mohammed Rafique, O'Connell, Philip J., Okpechi, Ikechi G., PECOITS FILHO, Roberto, SHAH, Kamal D., SOLA, Laura, Swanepoel, Charles, Tonelli, Marcello, TWAHIR, Ahmed, VAN BIESEN, Wim, VARGHESE, Cherian, Yang, Chih-Wei, ZUNIGA, Carlos, ABU ALFA, Ali K., ALJUBORI, Harith M., ALRUKHAIMI, Mona N., ANDREOLI, Sharon P., ASHUNTANTANG, Gloria, Bellorin-Font, Ezequiel, BERNIEH, Bassam, IBHAIS, Fuad M., BLAKE, Peter G., BROWN, Mark, BROWN, Edwina, BUNNAG, Sakarn, CHAN, Tak Mao, CHEN, Yuqing, CLAURE-DEL GRANADO, Rolando, CLAUS, Stefaan, COLLINS, Allan, COPPO, Rosanna, COUCHOUD, Cecile, CUETO-MANZANO, Alfonso, CULLIS, Brett, DOUTHAT, Walter, DREYER, Gavin, EIAM-ONG, Somchai, EKE, Felicia U., Feehally, John, GHNAIMAT, Mohammad A., LEONG, Bak, HASSAN, Mohamed H., HOU, Fan Fan, JAGER, Kitty, KALANTAR-ZADEH, Kamyar, Levin, Adeera, LIEW, Adrian, McKnight, Marla, TADESSE, Yewondwassesn, Morton, Rachael L., Muller, Elmi, Murtagh, Fliss E. M., Naicker, Saraladevi, Nangaku, Masaomi, NIANG, Abdou, OBRADOR, Gregorio T., OSSAREH, Shahrzad, Perl, Jeffrey, RAHMAN, Muhibur, RASHID, Harun Ur, RICHARDS, Marie, RONDEAU, Eric, SAHAY, Manisha, SALEH, Abdulkarim, SCHNEDITZ, Daniel, TCHOKHONELIDZE, Irma, TESAR, Vladimir, Trask, Michele, TUNGSANGA, Kriang, VACHHARAJANI, Tushar, WALKER, Rachael C., WALKER, Robert, WERE, Anthony J. O., YAO, Qiang, YEATES, Karen, YU, Xueqing, ZAKHAROVA, Elena, ZEMCHENKOV, Alexander, Turan Kazancıoğlu, Rümeyza, Zhao, Ming-Hui, and KAZANCIOĞLU, RÜMEYZA

Abstract

The global nephrology community recognizes the need for a cohesive strategy to address the growing problem of end-stage kidney disease (ESKD). In March 2018, the International Society of Nephrology hosted a summit on integrated ESKD care, including 92 individuals from around the globe with diverse expertise and professional backgrounds. The attendees were from 41 countries, including 16 participants from 11 low- and lower-middle-income countries. The purpose was to develop a strategic plan to improve worldwide access to integrated ESKD care, by identifying and prioritizing key activities across 8 themes: (i) estimates of ESKD burden and treatment coverage, (ii) advocacy, (iii) education and training/workforce, (iv) financing/funding models, (v) ethics, (vi) dialysis, (vii) transplantation, and (viii) conservative care. Action plans with prioritized lists of goals, activities, and key deliverables, and an overarching performance framework were developed for each theme. Examples of these key deliverables include improved data availability, integration of core registry measures and analysis to inform development of health care policy; a framework for advocacy; improved and continued stakeholder engagement; improved workforce training; equitable, efficient, and cost-effective funding models; greater understanding and greater application of ethical principles in practice and policy; definition and application of standards for safe and sustainable dialysis treatment and a set of measurable quality parameters; and integration of dialysis, transplantation, and comprehensive conservative care as ESKD treatment options within the context of overall health priorities. Intended users of the action plans include clinicians, patients and their families, scientists, industry partners, government decision makers, and advocacy organizations. Implementation of this integrated and comprehensive plan is intended to improve quality and access to care and thereby reduce serious health-related suffering of adults and children affected by ESKD worldwide.

Published
2019

41. May Measurement Month 2018: a pragmatic global screening campaign to raise awareness of blood pressure by the International Society of Hypertension

Author

Beaney, Thomas, Burrell, Louise M, Castillo, Rafael R, Charchar, Fadi J, Cro, Suzie, Damasceno, Albertino, Kruger, Ruan, Nilsson, Peter M, Prabhakaran, Dorairaj, Ramirez, Agustin J, Schlaich, Markus P, Schutte, Aletta E, Tomaszewski, Maciej, Touyz, Rhian, Wang, Ji-Guang, Weber, Michael A, Poulter, Neil R, Burazeri, Genc, Qirjako, Gentiana, Roshi, Enver, Cunashi, Rudina, Fernandes, Mario J C C, Victória Pereira, Savarino S, Neto, Marisa F M P, Oliveira, Pombalino N M, Feijão, Ana C G, Cerniello, Yamila, Marin, Marcos J, Garcia Vasquez, Fortunato, Espeche, Walter G, Stisman, Diego, Fuentes, Inés A, Zilberman, Juith M, Rodriguez, Pablo, Babinyan, Kamsar Yu, Engibaryan, Anna H, Avagyan, Avag M, Minasyan, Arsen A, Gevorkyan, Ani T, Carnagarin, Revathy, Carrington, Melinda J, Sharman, James E, Lee, Rebecca, Perl, Sabine, Niederl, Ella, Malik, Fazila-Tun-Nesa, Choudhury, Sohel R, Al Mamun, Mohammad A, Ishraquzzaman, Mir, Anthony, Fiona, Connell, Kenneth, De Backer, Tine L M, Krzesinski, Jea, Houenassi, Martin D, Houehanou, Corine Y, Sokolovic, Sekib, Bahtijarevic, Rankica, Tiro, Mary B, Mosepele, Mosepele, Masupe, Tiny K, Barroso, Weimar S, Gomes, Marco A M, Feitosa, Audes D M, Brandão, Andrea A, Miranda, Roberto D, Azevedo, Vanda M A A, Dias, Luis M, Garcia, Glenda D N, Martins, Idiana P P, Dzudie, Anastase, Kingue, Samuel, Djomou, Florent A N, Njume, Epie, Khan, Nadia, Lanas, Fernando T, Garcia, Maria S, Paccot, Melanie F, Torres, Pamela I, Li, Yan, Liu, Min, Xu, Liying, Li, Li, Chen, Xin, Deng, Junping, Zhao, Wenwu, Fu, Lingjuan, Zhou, Yi, Lopez-Jaramillo, Patricio, Otero, Johanna, Camacho, Paul A, Accini, Jose L, Sanchez, Gregorio, Arcos, Edgar, M’Buyamba-Kabangu, Jean-René, Katamba, Fortunat K, Ngoyi, Georges N, Buila, Nathan M, Bayauli, Pascal M, Ellenga Mbolla, Bertrand F, Bakekolo, Paterne R, Kouala Landa, Christian M, Kimbally Kaky, Gisele S, Kramoh, Euloge K, Ngoran, Yves N K, Olsen, Michael H, Valdez Valoy, Laura, Santillan, Marcos, Angel Rafael, Gonzalez Medina, Peñaherrera, Carlos E, Villalba, Jose, Ramirez, Maria I, Arteaga, Fabricio, Delgado, Patricia, Beistline, Holly, Cappuccio, Francesco P, Keitley, James, Tay, Tricia, Goshu, Dejuma Y, Kassie, Desalew M, Gebru, Sintayehu A, Pathak, Atul, Denolle, Thierry, Tsinamdzgvrishvili, Bezhan, Trapaidze, Dali, Sturua, Lela, Abesadze, Tamar, Grdzelidze, Nino, Grabfelder, Mark, Krämer, Bernhard K, Schmeider, Roland E, Twumasi-Ankrah, Betty, Tannor, Elliot K, Lincoln, Mary D, Deku, Enoch M, Wyss Quintana, Fernando S, Kenerson, John, Jean Baptiste, Emmanuela D, Saintilmond, Wideline W, Barrientos, Ana L, Peiger, Briggitte, Lagos, Ashley R, Forgas, Marcelo A, Lee, Vivian W Y, Tomlinson, Brian W Y, Járai, Zoltán, Páll, Dénes, More, Arun, Maheshwari, Anuj, Verma, Narsingh, Sharma, Meenakshi, Mukherjee, Tapan K, Patil, Mansi, Pulikkottil Jose, Arun, Takalkar, Anant, Turana, Yuda, Widyantoro, Bambang, Danny, Siska S, Djono, Suhar, Handari, Saskia D, Tambunan, Marihot, Tiksnadi, Badai B, Hermiawaty, Eka, Tavassoli, Elham, Zolfaghari, Mahsa, Dolan, Eamon, O'Brien, Eoin, Borghi, Claudio, Ferri, Claudio, Torlasco, Camilla, Parati, Gianfranco, Nwokocha, Chukwuemeka R, Nwokocha, Magdalene I, Ogola, Elijah N, Gitura, Bernard M, Barasa, Anders L, Barasa, Felix A, Wairagu, Anne W, Nalwa, Wafula Z, Najem, Robert N, Abu Alfa, Ali K, Fageh, Hatem A, Msalam, Omar M, Derbi, Hawa A, Bettamar, Kzaki A, Zakauskiene, Urte, Vickiene, Alvita, Calmes, Jessica, Alkerwi, Ala'a, Gantenbein, Manon, Ndhlovu, Henry L L, Masiye, Jones K, Chirwa, Maureen L, Nyirenda, Nancy M, Dhlamini, Tiyezge D, Chia, Yook C, Ching, Siew M, Devaraj, Navin K, Ouane, Nouhoum, Fane, Tidiani, Kowlessur, Sudhir, Ori, Bhooshun, Heecharan, Jaysing, Alcocer, Luis, Chavez, Adolfo, Ruiz, Griselda, Espinosa, Cutberto, Gomez-Alvarez, Enrique, Neupane, Dinesh, Bhattarai, Harikrishna, Ranabhat, Kamal, Adhikari, Tara B, Koirala, Sweta, Toure, Ibrahim A, Soumana, Kabirou H, Wahab, Kolawole W, Omotoso, Ayodele B, Sani, Mahmoud U, Okubadejo, Njideka U, Nadar, Sunil K, Al-Riyami, Hassan A, Ishaq, Mohammad, Memon, Feroz, Sidique, Sualat, Choudhry, Hafeez A, Khan, Rasheed A, Ayala, Myrian, Maidana, Angel J O, Bogado, Graciela GG, Ona, Deborah I, Atilano, Alberto, Granada, Carmela, Bartolome, Regina, Manese, Loudes, Mina, Arnold, Dumlao, Maria C, Villaruel, Mariyln C, Gomez, lynn, Jóźwiak, Jacek, Małyszko, Jolanta, Banach, Maciej, Mastej, Mirosław, de Carvalho Rodrigues, Manuel M, Martins, Luis L, Paval, Alexandra, Dorobantu, Maria, Konradi, Alexandra O, Chazova, Irina E, Rotar, Oxana, Spoares, Miryan C, Viegas, Deolsanik, Almustafa, Bader A, Alshurafa, Saleh A, Brady, Adrian, Bovet, Pascal, Viswanathan, Bharathi, Oladapo, Olulola O, Russell, James W, Brguljan-Hitij, Jana, Bozic, Nina, Knez, Judita, Dolenc, Primoz, Hassan, Mohammed M, Woodiwiss, Angela J, Myburgh, Caitlynd, Vally, Muhammed, Ruilope, Luis M, Molinero, Ana, Rodilla, Enrique, Gijón-Conde, Teresa, Beheiry, Hind M, Ali, I A, Osman, Asma A A, fahal, Naiema A W, Osman, Hana A, Altahir, Fatima, Persson, Margaretha, Wuerzner, Gregoire, Burkard, Thilo, Wang, Tzung-Dau, Lin, Hung-Ju, Pan, Heng-Yu, Chen, Wen-Jone, Lin, Eric, Mondo, Charles K, Ingabire, Prossie M, Khomazyuk, Tatyana TA, Krotova, Viktoriia V-Yu, Negresku, Elena, Evstigneeva, Olena, Bazargani, Nooshin NB, Agrawal, Amrish, Bin Belaila, Buthaina A, Suhail, Aisha M, Muhammed, Khalifa O, Shuri, Hassan H, Wainford, Richard D, Levy, Philip D, Boggia, José JG, Garré, Laura L, Hernandez-Hernandez, Rafael, Octavio-Seijas, Jose A, Lopez-Rivera, Jesus A, Morr, Igor, Duin, Amanda, Huynh, Minh V, Cao, Sinh T, Nguyen, Viet L, To, Muoi, Phan, Hung N, Cockroft, John, McDonnell, Barry, Goma, Fastone M, Syatalimi, Charity, Chifamba, Jephat, Gwini, Rudo, Tiburcio, Osiris Valdez, Xia, Xin, 20035632 - Kruger, Ruan, 10922180 - Schutte, Aletta Elisabeth, Beaney T., Burrell L.M., Castillo R.R., Charchar F.J., Cro S., Damasceno A., Kruger R., Nilsson P.M., Prabhakaran D., Ramirez A.J., Schlaich M.P., Schutte A.E., Tomaszewski M., Touyz R., Wang J.-G., Weber M.A., Poulter N.R., and Borghi C

Subjects
Male, Cardiac & Cardiovascular Systems, Cross-sectional study, Blood Pressure, 030204 cardiovascular system & hematology, Global Burden of Disease, 0302 clinical medicine, Surveys and Questionnaires, MMM Investigators, Mass Screening, 030212 general & internal medicine, 1102 Cardiorespiratory Medicine and Haematology, Antihypertensive medication, RISK, Global, Awareness, Middle Aged, PREVALENCE, Hypertension, Blood pressure, Screening, Raised blood pressure, Female, Cardiology and Cardiovascular Medicine, BURDEN, Life Sciences & Biomedicine, Control, Adult, medicine.medical_specialty, Fast Track Clinical Research, Opportunistic Sampling, 03 medical and health sciences, Internal medicine, medicine, SYSTEMATIC ANALYSIS, MANAGEMENT, Humans, Mass screening, Disease burden, Antihypertensive Agents, Science & Technology, business.industry, Case-control study, Blood Pressure Determination, Treatment, Editor's Choice, RAMADAN, Cross-Sectional Studies, Cardiovascular System & Hematology, Case-Control Studies, Cardiovascular System & Cardiology, business, Hypertension, Blood pressure, Screening, Global, Treatment, Control
Abstract

Aims Raised blood pressure (BP) is the biggest contributor to mortality and disease burden worldwide and fewer than half of those with hypertension are aware of it. May Measurement Month (MMM) is a global campaign set up in 2017, to raise awareness of high BP and as a pragmatic solution to a lack of formal screening worldwide. The 2018 campaign was expanded, aiming to include more participants and countries. Methods and results Eighty-nine countries participated in MMM 2018. Volunteers (≥18 years) were recruited through opportunistic sampling at a variety of screening sites. Each participant had three BP measurements and completed a questionnaire on demographic, lifestyle, and environmental factors. Hypertension was defined as a systolic BP ≥140 mmHg or diastolic BP ≥90 mmHg, or taking antihypertensive medication. In total, 74.9% of screenees provided three BP readings. Multiple imputation using chained equations was used to impute missing readings. 1 504 963 individuals (mean age 45.3 years; 52.4% female) were screened. After multiple imputation, 502 079 (33.4%) individuals had hypertension, of whom 59.5% were aware of their diagnosis and 55.3% were taking antihypertensive medication. Of those on medication, 60.0% were controlled and of all hypertensives, 33.2% were controlled. We detected 224 285 individuals with untreated hypertension and 111 214 individuals with inadequately treated (systolic BP ≥ 140 mmHg or diastolic BP ≥ 90 mmHg) hypertension. Conclusion May Measurement Month expanded significantly compared with 2017, including more participants in more countries. The campaign identified over 335 000 adults with untreated or inadequately treated hypertension. In the absence of systematic screening programmes, MMM was effective at raising awareness at least among these individuals at risk.

Published
2019
Full Text
View/download PDF

42. Immunochemical characterization of Na+/H+ exchanger isoform NHE4

Author

Pizzonia, John H., Biemesderfer, Daniel, Abu-Alfa, Ali K., Wu, Ming-Shiou, Exner, Marcus, Isenring, Paul, Igarashi, Peter, and Aronson, Peter S.

Subjects
Carrier proteins -- Research, Amino acids -- Research, Monoclonal antibodies -- Usage, Biological sciences
Abstract

A fusion protein consisting of 111 amino acids of NHE4 transport proteins was constructed using the low sequence similarity among NHEs in the COOH- terminal hydrophilic domain. The localization of NHE4 in rat was characterized in rats using isoform specific monoclonal antibodies. Results show that NHE4 was a protein of an estimated molecular mass of 65-70 kDa present abundantly in stomach but can also be detected in skeletal muscle, heart, kidney, uterus and liver. NHE4 was also observed to be higher in amount in the cortex than in the medulla of the kidneys.

Published
1998

44. Monoclonal antibodies for high-resolution localization of NHE3 in adult and neonatal rat kidney

Author

Biemesderfer, Daniel, Rutherford, Peter A., Nagy, Tamas, Pizzonia, John H., Abu-Alfa, Ali K., and Aronson, Peter S.

Subjects
Brush border membrane -- Research, Acidosis -- Research, Kidneys -- Research, Rats -- Research, Antibodies -- Research, Biological sciences
Abstract

The monoclonal antibodies for high-resolution localization of NH3 in adult and neonatal rat kidney were examined employing immunofluorenscence and immunoelectron microscopy. Result of the study revealed that the nephron development, as shown by the pattern in NHE3 staining, was similar to that of an adult nephron. Furthermore, NHE3 is expressed on the apical membrane during early stages of development.

Published
1997

45. Cinacalcet for Secondary Hyperparathyroidism in Patients Receiving Hemodialysis

Author

Block, Geoffrey A., Martin, Kevin J., de Francisco, Angel L.M., Turner, Stewart A., Avram, Morrell M., Suranyi, Michael G., Hercz, Gavril, Cunningham, John, Abu-Alfa, Ali K., Messa, Piergiorgio, Coyne, Daniel W., Locatelli, Francesco, Cohen, Raphael M., Evenepoel, Pieter, Moe, Sharon M., Fournier, Albert, Braun, Johann, McCary, Laura C., Zani, Valter J., Olson, Kurt A., Drueke, Tilman B., and Goodman, William G.

Published
2004
Full Text
View/download PDF

48. Dialysis initiation, modality choice, access, and prescription: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Author

Chan, Christopher T., primary, Blankestijn, Peter J., additional, Dember, Laura M., additional, Gallieni, Maurizio, additional, Harris, David C.H., additional, Lok, Charmaine E., additional, Mehrotra, Rajnish, additional, Stevens, Paul E., additional, Wang, Angela Yee-Moon, additional, Cheung, Michael, additional, Wheeler, David C., additional, Winkelmayer, Wolfgang C., additional, Pollock, Carol A., additional, Abu-Alfa, Ali K., additional, Bargman, Joanne M., additional, Bleyer, Anthony J., additional, Brown, Edwina A., additional, Davenport, Andrew, additional, Davies, Simon J., additional, Finkelstein, Frederic O., additional, Flythe, Jennifer E., additional, Goffin, Eric, additional, Golper, Thomas A., additional, Gómez, Rafael, additional, Hamano, Takayuki, additional, Hecking, Manfred, additional, Heimbürger, Olof, additional, Hole, Barnaby, additional, Hothi, Daljit K., additional, Ikizler, T. Alp, additional, Isaka, Yoshitaka, additional, Iseki, Kunitoshi, additional, Jha, Vivekanand, additional, Kawanishi, Hideki, additional, Kerr, Peter G., additional, Komenda, Paul, additional, Kovesdy, Csaba P., additional, Lacson, Ed, additional, Laville, Maurice, additional, Lee, Jung Pyo, additional, Lerma, Edgar V., additional, Levin, Nathan W., additional, Lichodziejewska-Niemierko, Monika, additional, Liew, Adrian, additional, Lindley, Elizabeth, additional, Lockridge, Robert S., additional, Madero, Magdalena, additional, Massy, Ziad A., additional, McCann, Linda, additional, Meyer, Klemens B., additional, Morton, Rachael L., additional, Nadeau-Fredette, Annie-Claire, additional, Okada, Hirokazu, additional, Perez, Jose, additional, Perl, Jeff, additional, Polkinghorne, Kevan R., additional, Riella, Miguel C., additional, Robinson, Bruce M., additional, Rocco, Michael V., additional, Rosansky, Steven J., additional, Rotmans, Joris I., additional, Fernanda Slon Roblero, María, additional, Tangri, Navdeep, additional, Tonelli, Marcello, additional, Tong, Allison, additional, Tsukamoto, Yusuke, additional, Tungsanga, Kriang, additional, Vachharajani, Tushar J., additional, van Loon, Ismay, additional, Watnick, Suzanne, additional, Weiner, Daniel E., additional, Wilkie, Martin, additional, and Zakharova, Elena, additional

Published
2019
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results