Search

Your search keyword '"Abo, Daisuke"' showing total 230 results
Start Over Author "Abo, Daisuke"
230 results on '"Abo, Daisuke"'

16. Study of hepatic toxicity in small liver tumors after photon or proton therapy based on factors predicting the benefits of proton

Author

Uchinami, Yusuke, Katoh, Norio, Abo, Daisuke, Morita, Ryo, Taguchi, Hiroshi, Fujita, Yoshihiro, Kanehira, Takahiro, Suzuki, Ryusuke, Miyamoto, Naoki, Takao, Seishin, Matsuura, Taeko, Sho, Takuya, Ogawa, Koji, Orimo, Tatsuya, Kakisaka, Tatsuhiko, Kobashi, Keiji, Aoyama, Hidefumi, Uchinami, Yusuke, Katoh, Norio, Abo, Daisuke, Morita, Ryo, Taguchi, Hiroshi, Fujita, Yoshihiro, Kanehira, Takahiro, Suzuki, Ryusuke, Miyamoto, Naoki, Takao, Seishin, Matsuura, Taeko, Sho, Takuya, Ogawa, Koji, Orimo, Tatsuya, Kakisaka, Tatsuhiko, Kobashi, Keiji, and Aoyama, Hidefumi

Abstract

Objectives: In a previous study of hepatic toxicity, the following three factors were identified to predict the benefits of proton beam therapy (PBT) for hepatocellular carcinomas (HCCs) with a maximum diameter of ≤5 cm and Child-pugh grade A (CP-A): number of tumors (1 vs ≥2), the location of tumors (hepatic hilum or others), and the sum of the diameters of lesions. The aim of this study is to analyze the association between these three factors and hepatic toxicity. Methods: We retrospectively reviewed patients of CP-A treated with PBT or photon stereotactic body radiotherapy (X-ray radiotherapy, XRT) for HCC ≤5 cm. For normal liver dose, the V5, V10, V20 (volumes receiving 5, 10, and 20 Gy at least), and the mean dose was evaluated. The albumin-bilirubin (ALBI) and CP score changes from the baseline were evaluated at 3 and 6 months after treatment. Results: In 89 patients (XRT: 48, PBT: 41), those with two or three (2-3) predictive factors were higher normal liver doses than with zero or one (0-1) factor. In the PBT group, the ALBI score worsened more in patients with 2-3 factors than those with 0-1 factor, at 3 months (median: 0.26 vs 0.02, p = 0.032) and at 6 months (median: 0.35 vs 0.10, p = 0.009). The ALBI score change in the XRT group and CP score change in either modality were not significantly different in the number of predictive factors. Conclusion: The predictive factor numbers predicted the ALBI score change in PBT but not in XRT. Advances in knowledge: This study suggest that the number of predictive factors previously identified (0-1 vs 2-3) were significantly associated with dosimetric parameters of the normal liver in both modalities. In the proton group, the number of predictive factors was associated with a worsening ALBI score at 3 and 6 months, but these associations were not found in the photon SBRT group., A correction has been published: British Journal of Radiology, Volume 97, Issue 1155, March 2024, Page 694, https://doi.org/10.1093/bjr/tqad058

Published
2023

17. Real-time tumor-tracking radiotherapy with SyncTraX for primary liver tumors requiring isocenter shift.

Author

Uchinami, Yusuke, Miyamoto, Naoki, Abo, Daisuke, Morita, Ryo, Ogawa, Koji, Kakisaka, Tatsuhiko, Suzuki, Ryusuke, Miyazaki, Tomohiko, Taguchi, Hiroshi, Katoh, Norio, and Aoyama, Hidefumi

Subjects
LIVER tumors, STEREOTACTIC radiotherapy, RADIOTHERAPY, RADIOTHERAPY safety, OVERALL survival, CONFIDENCE intervals
Abstract

The SyncTraX series enables real-time tumor-tracking radiotherapy through the real-time recognition of a fiducial marker using fluoroscopic images. In this system, the isocenter should be located within approximately 5–7.5 cm from the marker, depending on the version, owing to the limited field of view. If the marker is placed away from the tumor, the isocenter should be shifted toward the marker. This study aimed to investigate stereotactic body radiotherapy (SBRT) outcomes of primary liver tumors treated with SyncTraX in cases where the isocenter was shifted marginally or outside the planning target volume (PTV). Twelve patients with 13 liver tumors were included in the analysis. Their isocenter was shifted toward the marker and was placed marginally or outside the PTV. The prescribed doses were generally 40 Gy in four fractions or 48 Gy in eight fractions. The overall survival (OS) and local control (LC) rates were calculated using the Kaplan–Meier method. All patients completed the scheduled SBRT. The median distance between the fiducial marker and PTV centroid was 56.0 (interquartile range [IQR]: 52.7–66.7) mm. By shifting the isocenter toward the marker, the median distance between the marker and isocenter decreased to 34.0 (IQR: 33.4–39.7) mm. With a median follow-up period of 25.3 (range: 6.9–70.0) months, the 2-year OS and LC rates were 100.0% (95% confidence interval: 100–100). An isocenter shift makes SBRT with SyncTraX feasible in cases where the fiducial marker is distant from the tumor. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

20. Study of hepatic toxicity in small liver tumors after photon or proton therapy based on factors predicting the benefits of proton

Author

Uchinami, Yusuke, primary, Katoh, Norio, additional, Abo, Daisuke, additional, Morita, Ryo, additional, Taguchi, Hiroshi, additional, Fujita, Yoshihiro, additional, Kanehira, Takahiro, additional, Suzuki, Ryusuke, additional, Miyamoto, Naoki, additional, Takao, Seishin, additional, Matsuura, Taeko, additional, Sho, Takuya, additional, Ogawa, Koji, additional, Orimo, Tatsuya, additional, Kakisaka, Tatsuhiko, additional, Kobashi, Keiji, additional, and Aoyama, Hidefumi, additional

Published
2023
Full Text
View/download PDF

22. Treatment outcomes of stereotactic body radiation therapy using a real-time tumor-tracking radiotherapy system for hepatocellular carcinomas

Author

Uchinami, Yusuke, Katoh, Norio, Abo, Daisuke, Taguchi, Hiroshi, Yasuda, Koichi, Nishioka, Kentaro, Soyama, Takeshi, Morita, Ryo, Miyamoto, Naoki, Suzuki, Ryusuke, Sho, Takuya, Nakai, Masato, Ogawa, Koji, Kakisaka, Tatsuhiko, Orimo, Tatsuya, Kamiyama, Toshiya, Shimizu, Shinichi, and Aoyama, Hidefumi

Subjects
stereotactic body radiotherapy, real-time tumor-tracking radiotherapy, albumin-bilirubin grade, hepatocellular carcinoma
Abstract

Aim To report the outcomes of stereotactic body radiotherapy using a real-time tumor-tracking radiotherapy system for hepatocellular carcinoma patients. Methods From January 2005 to July 2018, 63 patients with 74 lesions with a maximum diameter = 9 was included, and 85.6% had a score of 5 or 6. Using the biological effective dose (BED) with an alpha/beta ratio of 10 (BED10), the median dose in BED10 at the reference point was 76.8 Gy (range 60-122.5 Gy). Overall survival (OS) and local control rates were assessed using the Kaplan-Meier method. Results With a median follow-up period of 24.6 months (range 0.9-118.4 months), the 1-year and 2-year OS rates were 86.8% (95% confidence interval [95% CI] 75.8-93.3) and 71.1% (57.8-81.6), respectively. The 2-year OS was 89.6% in patients with the baseline modified albumin-bilirubin (mALBI) grade =1, and 61.7% in patients with grade >= 2a. In the multivariate analysis, the mALBI grade (=1 vs. >= 2a) was a significant factor for OS (p = 0.028, 95% CI 1.11-6.18). The 1-year and 2-year local control rates were 100% (100-100%) and 92.0% (77.5-97.5%). The local control rates were significantly higher in the BED10 >= 100 Gy group than in the BED10 = 100 Gy to the reference point.

Published
2021

25. Usefulness of preoperative simulation with patient-specific hollow vascular models for high-flow renal arteriovenous fistula embolization using a preloading coil-in-plug technique

Author

Morita, Ryo, primary, Abo, Daisuke, additional, Soyama, Takeshi, additional, Imai, Tetsuaki, additional, Takahashi, Bunya, additional, Yoshino, Yuki, additional, Kinota, Naoya, additional, Hamaguchi, Hiroyuki, additional, Kameda, Takuto, additional, and Kudo, Kohsuke, additional

Published
2022
Full Text
View/download PDF

31. Sharp recanalization and rendezvous technique for biliary occlusions due to spacious bile leak after hepatectomy

Author

Hajime Hirata, Masaki Kuwatani, and Abo Daisuke

Subjects
medicine.medical_specialty, Colorectal cancer, medicine.medical_treatment, Intrahepatic bile ducts, Hilum (biology), 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, medicine, Bile, Hepatectomy, Humans, Bile leak, Cholangiopancreatography, Endoscopic Retrograde, Cholestasis, Hepatology, business.industry, Cancer, medicine.disease, Catheter, Bile Ducts, Intrahepatic, 030220 oncology & carcinogenesis, Endoscopic retrograde cholangiography, Surgery, Radiology, Bile Ducts, business
Abstract

A 65-year-old male was referred to our hospital for treatment of biliary strictures and spacious bile leak (biloma) near the hepatic hilum 2 months after hepatectomy for metastatic cancer in the left liver lobe (Fig A). He had undergone several resections of the rectal cancer and its metastases to the left liver lobe. Under endoscopic retrograde cholangiography guidance, a catheter could not be inserted into the right intrahepatic bile duct because of the biloma (Fig B).

Published
2021

41. Impact of gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging on the prognosis of hepatocellular carcinoma after surgery

Author

1000040755576, Shimada, Shingo, 1000080322816, Kamiyama, Toshiya, 1000040583092, Kakisaka, Tatsuhiko, 1000080711861, Orimo, Tatsuya, Nagatsu, Akihisa, Asahi, Yoh, 1000020876247, Sakamoto, Yuzuru, 1000030399844, Abo, Daisuke, 1000060374237, Kamachi, Hirofumi, 1000070363364, Taketomi, Akinobu, 1000040755576, Shimada, Shingo, 1000080322816, Kamiyama, Toshiya, 1000040583092, Kakisaka, Tatsuhiko, 1000080711861, Orimo, Tatsuya, Nagatsu, Akihisa, Asahi, Yoh, 1000020876247, Sakamoto, Yuzuru, 1000030399844, Abo, Daisuke, 1000060374237, Kamachi, Hirofumi, 1000070363364, and Taketomi, Akinobu

Abstract

Background and Aim: Gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (EOB-MRI) has been recognized as a useful imaging technique to distinguish the biological behavior of hepatocellular carcinoma (HCC). Methods: We analyzed 217 hepatectomy recipients with HCCs measuring 10 cm or less. We divided the patients into a decreased intensity (DI) group (n = 189, 87%) and an increased or neutral intensity (INI) group (n = 28, 13%) according to the ratio of tumor intensity to liver intensity during the hepatobiliary phase (HBP). According to the ratio of the maximum tumor diameter (including peritumoral hypointensity) between HBP images and precontrast T1-weighted images (RHBPP), we divided the patients as follows: The group whose RHBPP was >= 1.036 was the high RHBPP group (n = 60, 28%), and the group whose RHBPP was <1.036 was the low RHBPP group (n = 157, 72%). We investigated the prognoses and clinicopathological characteristics of these patients. Results: DI versus INI was not a prognostic factor for either survival or recurrence; however, a high RHBPP was an independent predictor of unfavorable survival and recurrence in patients. In addition, the INI group showed significantly lower alpha-fetoprotein (AFP) levels and higher rates of well-differentiated HCC and ICGR15 >= 15% than the DI group. The high RHBPP group showed significantly higher rates of vascular invasion and poorly differentiated HCC than the low RHBPP group. Conclusions: A high RHBPP by EOB-MRI is a preoperative predictor of vascular invasion and an unfavorable prognostic factor for survival and recurrence. These patients might be considered for highly curative operations such as anatomical liver resection.

Published
2021

42. Impact of gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging on the prognosis of hepatocellular carcinoma after surgery

Author

Shimada, Shingo, Kamiyama, Toshiya, Kakisaka, Tatsuhiko, Orimo, Tatsuya, Nagatsu, Akihisa, Asahi, Yoh, Sakamoto, Yuzuru, Abo, Daisuke, Kamachi, Hirofumi, Taketomi, Akinobu, Shimada, Shingo, Kamiyama, Toshiya, Kakisaka, Tatsuhiko, Orimo, Tatsuya, Nagatsu, Akihisa, Asahi, Yoh, Sakamoto, Yuzuru, Abo, Daisuke, Kamachi, Hirofumi, and Taketomi, Akinobu

Abstract

Background and Aim: Gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (EOB-MRI) has been recognized as a useful imaging technique to distinguish the biological behavior of hepatocellular carcinoma (HCC). Methods: We analyzed 217 hepatectomy recipients with HCCs measuring 10 cm or less. We divided the patients into a decreased intensity (DI) group (n = 189, 87%) and an increased or neutral intensity (INI) group (n = 28, 13%) according to the ratio of tumor intensity to liver intensity during the hepatobiliary phase (HBP). According to the ratio of the maximum tumor diameter (including peritumoral hypointensity) between HBP images and precontrast T1-weighted images (RHBPP), we divided the patients as follows: The group whose RHBPP was >= 1.036 was the high RHBPP group (n = 60, 28%), and the group whose RHBPP was <1.036 was the low RHBPP group (n = 157, 72%). We investigated the prognoses and clinicopathological characteristics of these patients. Results: DI versus INI was not a prognostic factor for either survival or recurrence; however, a high RHBPP was an independent predictor of unfavorable survival and recurrence in patients. In addition, the INI group showed significantly lower alpha-fetoprotein (AFP) levels and higher rates of well-differentiated HCC and ICGR15 >= 15% than the DI group. The high RHBPP group showed significantly higher rates of vascular invasion and poorly differentiated HCC than the low RHBPP group. Conclusions: A high RHBPP by EOB-MRI is a preoperative predictor of vascular invasion and an unfavorable prognostic factor for survival and recurrence. These patients might be considered for highly curative operations such as anatomical liver resection.

Published
2021

45. Efficacy of therapy for advanced hepatocellular carcinoma: Intra-arterial 5-fluorouracil and subcutaneous interferon with image-guided radiation

Author

Chuma, Makoto, Taguchi, Hiroshi, Yamamoto, Yoshiya, Shimizu, Shinichi, Nakanishi, Mitsuru, Ogawa, Koji, Sho, Takuya, Horimoto, Hiromasa, Kobayashi, Tomoe, Nakai, Masato, Terashita, Katsumi, Sakuhara, Yusuke, Abo, Daisuke, Tsukuda, Yoko, Tsunematsu, Seiji, Hige, Shuhei, Kato, Mototsugu, Shirato, Hiroki, and Asaka, Masahiro

Published
2011
Full Text
View/download PDF

46. Impact of gadolinium‐ethoxybenzyl‐diethylenetriamine pentaacetic acid‐enhanced magnetic resonance imaging on the prognosis of hepatocellular carcinoma after surgery

Author

Shimada, Shingo, primary, Kamiyama, Toshiya, additional, Kakisaka, Tatsuhiko, additional, Orimo, Tatsuya, additional, Nagatsu, Akihisa, additional, Asahi, Yoh, additional, Sakamoto, Yuzuru, additional, Abo, Daisuke, additional, Kamachi, Hirofumi, additional, and Taketomi, Akinobu, additional

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results