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A multiple dose regimen is a concept that is used for certain diseases as arthritis, heart diseases etc. It is used to increase the therapeutic activity and clinical efficacy of the drugs. Drugs are usually used in single doses to produce acute effect but in cases where chronic affect is required multiple dosage regimen is required. Designing the dosage regimen and maintaining the drug concentration in blood plasma after administration are the primary goals to achieve safety and efficacy. That is to maintain drug concentration in therapeutic window. Moreover, the IV infusion and continuous IV diffusion is reviewed.

With time viral infections are increasing day by day due to various reasons like new viruses, the resistance of viruses to antiviral therapy, and mutation of one form of the virus to another form; these types of problems create many challenges in the field of research. Furthermore, a lot of challenges are encountered in the treatment of antiviral therapy, like interaction with other medication and use of increased frequency and a high dose of antiviral due to infection in CNS or synovial fluid where drug permeation is less. Consequently, toxicity and other side effect chances will be more. Nano-technological approaches are used to overcome these challenges. The beneficial properties come from such engineering, including stimuli sensitivity, targetability, and longevity; these are all combined to give multifunctional nano-carriers that concurrently execute different beneficial tasks