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Mohamed Sheikh Hassan,1,2 Abdiwahid Ahmed Ibrahim,1 Engin Nakus,1 Bakar Ali Adam,1 Nor Osman Sidow,1 Mohamed Farah Osman Hidig,1 Said Abdi Mohamed,1 Abdulkadir Ahmed Mohamed,1 Abdulkamil Abdullahi Adani,3 Yahye Garad Mohamed,4 Ismail Gedi Ibrahim,4 Said Abdirahman Ahmed5 1Department of Neurology, Mogadishu Somali Turkish Training and Research Hospital, Mogadishu, Somalia; 2Faculty of Medicine and Surgery, Mogadishu University, Mogadishu, Somalia; 3Department of Internal Medicine, Mogadishu Somali Turkish Training and Research Hospital, Mogadishu, Somalia; 4Department of Radiology, Mogadishu Somali Turkish Training and Research Hospital, Mogadishu, Somalia; 5Department of Cardiology, Mogadishu Somali Turkish Training and Research Hospital, Mogadishu, SomaliaCorrespondence: Abdiwahid Ahmed Ibrahim, Email drabdiwahid00@gmail.comAbstract: Cerebral venous thrombosis (CVT) is a less common type of stroke, mostly in young patients. The majority of these cases are due to thrombosis of superior sagittal sinus and transverse sinus. Isolated thrombosis of the inferior sagittal sinus is very rare. Here, we report a 22-year-old male patient with no significant past medical history who presented to the emergency department of our hospital with a convulsion, decreased level of consciousness, and right side weakness. His laboratory investigations, including the coagulation profile, were normal. A non-contrast brain CT showed a 5 × 3 cm hematoma in the left parasagittal parietal lobe with no associated midline shift or intraventricular extension. The cerebral magnetic resonance (MR) angiogram did not show any underlying aneurysm or vascular lesion. However, the cranial MR venogram showed inferior sagittal sinus thrombosis, while other cranial veins and dural sinuses were patent. The patient was admitted to the hospital and managed with low-molecular-weight heparin and warfarin sequentially. He had significant improvement (consciousness and weakness have improved, and seizures are u