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1. A Hybrid Approach for Subsurface Illumination Analysis in Shallow Gas Region: A Case Study in Malay Basin

Author: Abdul Latiff, A. H., Ghosh, D. P., Awang, Mariyamni, editor, Negash, Berihun Mamo, editor, Md Akhir, Nur Asyraf, editor, and Lubis, Luluan Almanna, editor
Published: 2015
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2. Rhinitis associated with asthma is distinct from rhinitis alone:The ARIA-MeDALL hypothesis

Author: Bousquet, J, Melén, E, Haahtela, T, Koppelman, G H, Togias, A, Valenta, R, Akdis, C A, Czarlewski, W, Rothenberg, M, Valiulis, A, Wickman, M, Akdis, M, Aguilar, D, Bedbrook, A, Bindslev-Jensen, C, Bosnic-Anticevich, S, Boulet, L P, Brightling, C E, Brussino, L, Burte, E, Bustamante, M, Canonica, G W, Cecchi, L, Celedon, J C, Chaves Loureiro, C, Costa, E, Cruz, A A, Erhola, M, Gemicioglu, B, Fokkens, W J, Garcia-Aymerich, J, Guerra, S, Heinrich, J, Ivancevich, J C, Keil, T, Klimek, L, Kuna, P, Kupczyk, M, Kvedariene, V, Larenas-Linnemann, D E, Lemonnier, N, Lodrup Carlsen, K C, Louis, R, Makela, M, Makris, M, Maurer, M, Momas, I, Morais-Almeida, M, Mullol, J, Naclerio, R N, Nadeau, K, Nadif, R, Niedoszytko, M, Okamoto, Y, Ollert, M, Papadopoulos, N G, Passalacqua, G, Patella, V, Pawankar, R, Pham-Thi, N, Pfaar, O, Regateiro, F S, Ring, J, Rouadi, P W, Samolinski, B, Sastre, J, Savouré, M, Scichilone, N, Shamji, M H, Sheikh, A, Siroux, V, Sousa-Pinto, B, Standl, M, Sunyer, J, Taborda-Barata, L, Toppila-Salmi, S, Torres, M J, Tsiligianni, I, Valovirta, E, Vandenplas, O, Ventura, M T, Weiss, S, Yorgancioglu, A, Zhang, L, Abdul Latiff, A H, Aberer, W, Agache, I, Al-Ahmad, M, Alobid, I, Ansotegui, I J, Arshad, S H, Asayag, E, Barbara, C, Baharudin, A, Battur, L, Bennoor, K S, Berghea, E C, Bergmann, K C, Bernstein, D, Bewick, M, Blain, H, Bonini, M, Braido, F, Buhl, R, Bumbacea, R S, Bush, A, Calderon, M, Calvo-Gil, M, Camargos, P, Caraballo, L, Cardona, V, Carr, W, Carreiro-Martins, P, Casale, T, Cepeda Sarabia, A M, Chandrasekharan, R, Charpin, D, Chen, Y Z, Cherrez-Ojeda, I, Chivato, T, Chkhartishvili, E, Christoff, G, Chu, D K, Cingi, C, Correia de Sousa, J, Corrigan, C, Custovic, A, D'Amato, G, Del Giacco, S, De Blay, F, Devillier, P, Didier, A, do Ceu Teixeira, M, Dokic, D, Douagui, H, Doulaptsi, M, Durham, S, Dykewicz, M, Eiwegger, T, El-Sayed, Z A, Emuzyte, R, Fiocchi, A, Fyhrquist, N, Gomez, R M, Gotua, M, Guzman, M A, Hagemann, J, Hamamah, S, Halken, S, Halpin, D M G, Hofmann, M, Hossny, E, Hrubiško, M, Irani, C, Ispayeva, Z, Jares, E, Jartti, T, Jassem, E, Julge, K, Just, J, Jutel, M, Kaidashev, I, Kalayci, O, Kalyoncu, A F, Kardas, P, Kirenga, B, Kraxner, H, Kull, I, Kulus, M, La Grutta, S, Lau, S, Le Tuyet Thi, L, Levin, M, Lipworth, B, Lourenço, O, Mahboub, B, Martinez-Infante, E, Matricardi, P, Miculinic, N, Migueres, N, Mihaltan, F, Mohammad, Y, Moniuszko, M, Montefort, S, Neffen, H, Nekam, K, Nunes, E, Nyembue Tshipukane, D, O'Hehir, R, Ogulur, I, Ohta, K, Okubo, K, Ouedraogo, S, Olze, H, Pali-Schöll, I, Palomares, O, Palosuo, K, Panaitescu, C, Panzner, P, Park, H S, Pitsios, C, Plavec, D, Popov, T A, Puggioni, F, Quirce, S, Recto, M, Repka-Ramirez, M S, Robalo Cordeiro, C, Roche, N, Rodriguez-Gonzalez, M, Romantowski, J, Rosario Filho, N, Rottem, M, Sagara, H, Serpa, F S, Sayah, Z, Scheire, S, Schmid-Grendelmeier, P, Sisul, J C, Sole, D, Soto-Martinez, M, Sova, M, Sperl, A, Spranger, O, Stelmach, R, Suppli Ulrik, C, Thomas, M, To, T, Todo-Bom, A, Tomazic, P V, Urrutia-Pereira, M, Valentin-Rostan, M, Van Ganse, E, van Hage, M, Vasankari, T, Vichyanond, P, Viegi, G, Wallace, D, Wang, D Y, Williams, S, Worm, M, Yiallouros, P, Yusuf, O, Zaitoun, F, Zernotti, M, Zidarn, M, Zuberbier, J, Fonseca, J A, Zuberbier, T, Anto, J M, Bousquet, J, Melén, E, Haahtela, T, Koppelman, G H, Togias, A, Valenta, R, Akdis, C A, Czarlewski, W, Rothenberg, M, Valiulis, A, Wickman, M, Akdis, M, Aguilar, D, Bedbrook, A, Bindslev-Jensen, C, Bosnic-Anticevich, S, Boulet, L P, Brightling, C E, Brussino, L, Burte, E, Bustamante, M, Canonica, G W, Cecchi, L, Celedon, J C, Chaves Loureiro, C, Costa, E, Cruz, A A, Erhola, M, Gemicioglu, B, Fokkens, W J, Garcia-Aymerich, J, Guerra, S, Heinrich, J, Ivancevich, J C, Keil, T, Klimek, L, Kuna, P, Kupczyk, M, Kvedariene, V, Larenas-Linnemann, D E, Lemonnier, N, Lodrup Carlsen, K C, Louis, R, Makela, M, Makris, M, Maurer, M, Momas, I, Morais-Almeida, M, Mullol, J, Naclerio, R N, Nadeau, K, Nadif, R, Niedoszytko, M, Okamoto, Y, Ollert, M, Papadopoulos, N G, Passalacqua, G, Patella, V, Pawankar, R, Pham-Thi, N, Pfaar, O, Regateiro, F S, Ring, J, Rouadi, P W, Samolinski, B, Sastre, J, Savouré, M, Scichilone, N, Shamji, M H, Sheikh, A, Siroux, V, Sousa-Pinto, B, Standl, M, Sunyer, J, Taborda-Barata, L, Toppila-Salmi, S, Torres, M J, Tsiligianni, I, Valovirta, E, Vandenplas, O, Ventura, M T, Weiss, S, Yorgancioglu, A, Zhang, L, Abdul Latiff, A H, Aberer, W, Agache, I, Al-Ahmad, M, Alobid, I, Ansotegui, I J, Arshad, S H, Asayag, E, Barbara, C, Baharudin, A, Battur, L, Bennoor, K S, Berghea, E C, Bergmann, K C, Bernstein, D, Bewick, M, Blain, H, Bonini, M, Braido, F, Buhl, R, Bumbacea, R S, Bush, A, Calderon, M, Calvo-Gil, M, Camargos, P, Caraballo, L, Cardona, V, Carr, W, Carreiro-Martins, P, Casale, T, Cepeda Sarabia, A M, Chandrasekharan, R, Charpin, D, Chen, Y Z, Cherrez-Ojeda, I, Chivato, T, Chkhartishvili, E, Christoff, G, Chu, D K, Cingi, C, Correia de Sousa, J, Corrigan, C, Custovic, A, D'Amato, G, Del Giacco, S, De Blay, F, Devillier, P, Didier, A, do Ceu Teixeira, M, Dokic, D, Douagui, H, Doulaptsi, M, Durham, S, Dykewicz, M, Eiwegger, T, El-Sayed, Z A, Emuzyte, R, Fiocchi, A, Fyhrquist, N, Gomez, R M, Gotua, M, Guzman, M A, Hagemann, J, Hamamah, S, Halken, S, Halpin, D M G, Hofmann, M, Hossny, E, Hrubiško, M, Irani, C, Ispayeva, Z, Jares, E, Jartti, T, Jassem, E, Julge, K, Just, J, Jutel, M, Kaidashev, I, Kalayci, O, Kalyoncu, A F, Kardas, P, Kirenga, B, Kraxner, H, Kull, I, Kulus, M, La Grutta, S, Lau, S, Le Tuyet Thi, L, Levin, M, Lipworth, B, Lourenço, O, Mahboub, B, Martinez-Infante, E, Matricardi, P, Miculinic, N, Migueres, N, Mihaltan, F, Mohammad, Y, Moniuszko, M, Montefort, S, Neffen, H, Nekam, K, Nunes, E, Nyembue Tshipukane, D, O'Hehir, R, Ogulur, I, Ohta, K, Okubo, K, Ouedraogo, S, Olze, H, Pali-Schöll, I, Palomares, O, Palosuo, K, Panaitescu, C, Panzner, P, Park, H S, Pitsios, C, Plavec, D, Popov, T A, Puggioni, F, Quirce, S, Recto, M, Repka-Ramirez, M S, Robalo Cordeiro, C, Roche, N, Rodriguez-Gonzalez, M, Romantowski, J, Rosario Filho, N, Rottem, M, Sagara, H, Serpa, F S, Sayah, Z, Scheire, S, Schmid-Grendelmeier, P, Sisul, J C, Sole, D, Soto-Martinez, M, Sova, M, Sperl, A, Spranger, O, Stelmach, R, Suppli Ulrik, C, Thomas, M, To, T, Todo-Bom, A, Tomazic, P V, Urrutia-Pereira, M, Valentin-Rostan, M, Van Ganse, E, van Hage, M, Vasankari, T, Vichyanond, P, Viegi, G, Wallace, D, Wang, D Y, Williams, S, Worm, M, Yiallouros, P, Yusuf, O, Zaitoun, F, Zernotti, M, Zidarn, M, Zuberbier, J, Fonseca, J A, Zuberbier, T, and Anto, J M
Abstract: Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of “one-airway-one-disease,” coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhinitis and its Impact on Asthma (ARIA), (ii) new insights into polysensitization and multimorbidity, (iii) advances in mHealth for novel phenotype definitions, (iv) confirmation in canonical epidemiologic studies, (v) genomic findings, (vi) treatment approaches, and (vii) novel concepts on the onset of rhinitis and multimorbidity. One recent concept, bringing together upper- and lower-airway allergic diseases with skin, gut, and neuropsychiatric multimorbidities, is the “Epithelial Barrier Hypothesis.” This review determined that the “one-airway-one-disease” concept does not always hold true and that several phenotypes of disease can be defined. These phenotypes include an extreme “allergic” (asthma) phenotype combining asthma, rhinitis, and conjunctivitis. Rhinitis alone and rhinitis and asthma multimorbidity represent two distinct diseases with the following differences: (i) genomic and transcriptomic background (Toll-Like Receptors and IL-17 for rhinitis alone as a local disease; IL-33 and IL-5 for allergic and non-allergic multimorbidity as a systemic disease), (ii) allergen sensitization patterns (mono- or pauci-sensitization versus polysensitization), (iii) severity of symptoms, and (iv) treatment response. In conclusion, rhinitis alone (local disease) and rhinitis with asthma multimorbidity (systemic disease) should be considered as two distinct diseases, possibly modulated by the microbiome, and may be a model for understanding the epidemics of chronic and autoimmune diseases., Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of "one-airway-one-disease," coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhinitis and its Impact on Asthma (ARIA), (ii) new insights into polysensitization and multimorbidity, (iii) advances in mHealth for novel phenotype definitions, (iv) confirmation in canonical epidemiologic studies, (v) genomic findings, (vi) treatment approaches, and (vii) novel concepts on the onset of rhinitis and multimorbidity. One recent concept, bringing together upper- and lower-airway allergic diseases with skin, gut, and neuropsychiatric multimorbidities, is the "Epithelial Barrier Hypothesis." This review determined that the "one-airway-one-disease" concept does not always hold true and that several phenotypes of disease can be defined. These phenotypes include an extreme "allergic" (asthma) phenotype combining asthma, rhinitis, and conjunctivitis. Rhinitis alone and rhinitis and asthma multimorbidity represent two distinct diseases with the following differences: (i) genomic and transcriptomic background (Toll-Like Receptors and IL-17 for rhinitis alone as a local disease; IL-33 and IL-5 for allergic and non-allergic multimorbidity as a systemic disease), (ii) allergen sensitization patterns (mono- or pauci-sensitization versus polysensitization), (iii) severity of symptoms, and (iv) treatment response. In conclusion, rhinitis alone (local disease) and rhinitis with asthma multimorbidity (systemic disease) should be considered as two distinct diseases, possibly modulated by the microbiome, and may be a model for understanding the epidemics of chronic and autoimmune diseases.
Published: 2023

3. Rhinitis associated with asthma is distinct from rhinitis alone: The ARIA-MeDALL hypothesis

Author: Bousquet, J, Melén, E, Haahtela, T, Koppelman, G H, Togias, A, Valenta, R, Akdis, C A, Czarlewski, W, Rothenberg, M, Valiulis, A, Wickmann, M, Aguilar, D, Akdis, M, Ansotegui, I J, Barbara, C, Bedbrook, A, Bindslev Jensen, C, Bosnic-Anticevich, S, Boulet, L P, Brightling, C E, Brussino, L, Burte, E, Bustamante, M, Canonica, G W, Cecchi, L, Celedon, J C, Chaves-Loureiro, C, Costa, E, Cruz, A A, Erhola, M, Gemicioglu, B, Fokkens, W J, Garcia Aymerich, J, Guerra, S, Heinrich, J, Ivancevich, J C, Keil, T, Klimek, L, Kuna, P, Kupczyk, M, Kvedariene, V, Larenas-Linnemann, D E, Lemonnier, N, Lodrup Carlsen, K C, Louis, R, Makris, M, Maurer, M, Momas, I, Morais-Almeida, M, Mullol, J, Naclerio, R N, Nadeau, K, Nadif, R, Niedoszytko, M, Okamoto, Y, Ollert, M, Papadopoulos, N G, Passalacqua, G, Patella, V, Pawankar, R, Pham-Thi, N, Pfaar, O, Regateiro, F S, Ring, J, Rouadi, P W, Samolinski, B, Sastre, J, Savouré, M, Scichilone, N, Shamji, M H, Sheikh, A, Siroux, V, Sousa-Pinto, B, Standl, M, Sunyer, J, Taborda-Barata, L, Toppila-Salmi, S, Torres, M J, Tsiligianni, I, Valovirta, E, Vandenplas, O, Ventura, M T, Weiss, S, Yorgancioglu, A, Zhang, L, Abdul Latiff, A H, Aberer, W, Agache, I, Al-Ahmad, M, Alobid, I, Arshad, H S, Asayag, E, Baharudin, A, Battur, L, Bennoor, K S, Berghea, E C, Bergmann, K C, Bernstein, D, Bewick, Michael, Blain, H, Bonini, M, Braido, F, Buhl, R, Bumbacea, R, Bush, A, Calderon, M, Calvo, G, Camargos, P, Caraballo, L, Cardona, V, Carr, W, Carreiro-Martins, P, Casale, T, Cepeda Sarabia, A M, Chandrasekharan, R, Charpin, D, Chen, Y Z, Cherrez-Ojeda, I, Chivato, T, Chkhartishvili, E, Christoff, G, Chu, D K, Cingi, C, Correia da Sousa, J, Corrigan, C, Custovic, A, D'Amato, G, Del Giacco, S, De Blay, F, Devillier, P, Didier, A, do Ceu Teixeira, M, Dokic, D, Douagui, H, Doulaptsi, M, Durham, S, Dykewicz, M, Eiwegger, T, El-Sayed, Z A, Emuzyte, R, Fiocchi, A, Fyhrquist, N, Gomez, R M, Gotua, M, Guzman, M A, Hagemann, J, Hamamah, S, Halken, S, Halpin, D M G, Hofmann, M, Hossny, E, Hrubiško, M, Irani, C, Ispayeva, Z, Jares, E, Jartti, T, Jassem, E, Julge, K, Just, J, Jutel, M, Kaidashev, I, Kalayci, O, Kalyoncu, O, Kardas, P, Kirenga, B, Kraxner, H, Kull, I, Kulus, M, La Gruta, S, Lau, S, Le Tuyet Thi, L, Levin, M, Lipworth, B, Lourenço, O, Mahboub, B, Mäkelä, M J, Martinez-Infante, E, Matricardi, P, Miculinic, N, Migueres, N, Mihaltan, F, Mohamad, Y, Moniusko, M, Montefort, S, Neffen, H, Nekam, K, Nunes, E, Nyembue Tshipukane, D, O'Hehir, R E, Ogulur, I, Ohta, K, Okubo, K, Ouedraogo, S, Olze, H, Pali-Schöll, I, Palomares, O, Palosuo, K, Panaitescu, C, Panzner, P, Park, H S, Pitsios, C, Plavec, D, Popov, T A, Puggioni, F, Quirce, S, Recto, M, Repka-Ramirez, R, Roballo-Cordeiro, C, Roche, N, Rodriguez-Gonzales, M, Romantowski, J, Rosario Filho, N, Rottem, M, Sagara, H, Sarquis-Serpa, F, Sayah, Z, Scheire, S, Schmid-Grendelmeier, P, Sisul, J C, Sole, D, Soto-Martinez, M, Sova, M, Sperl, A, Spranger, O, Stelmach, R, Suppli Ulrik, C, Thomas, M, To, T, Todo-Bom, A, Tomazic, P V, Urrutia-Pereira, M, Valentin-Rostan, M, van Ganse, E, Van Hage, M, Vasankari, T, Vichyanond, P, Viegi, G, Wallace, D, Wang, D Y, Williams, S, Worm, M, Yiallouros, P, Yusuf, O, Zaitoun, F, Zernotti, M, Zidarn, M, Zuberbier, J, Fonseca, J A, Zuberbier, T, Anto, J M, Bousquet, J, Melén, E, Haahtela, T, Koppelman, G H, Togias, A, Valenta, R, Akdis, C A, Czarlewski, W, Rothenberg, M, Valiulis, A, Wickmann, M, Aguilar, D, Akdis, M, Ansotegui, I J, Barbara, C, Bedbrook, A, Bindslev Jensen, C, Bosnic-Anticevich, S, Boulet, L P, Brightling, C E, Brussino, L, Burte, E, Bustamante, M, Canonica, G W, Cecchi, L, Celedon, J C, Chaves-Loureiro, C, Costa, E, Cruz, A A, Erhola, M, Gemicioglu, B, Fokkens, W J, Garcia Aymerich, J, Guerra, S, Heinrich, J, Ivancevich, J C, Keil, T, Klimek, L, Kuna, P, Kupczyk, M, Kvedariene, V, Larenas-Linnemann, D E, Lemonnier, N, Lodrup Carlsen, K C, Louis, R, Makris, M, Maurer, M, Momas, I, Morais-Almeida, M, Mullol, J, Naclerio, R N, Nadeau, K, Nadif, R, Niedoszytko, M, Okamoto, Y, Ollert, M, Papadopoulos, N G, Passalacqua, G, Patella, V, Pawankar, R, Pham-Thi, N, Pfaar, O, Regateiro, F S, Ring, J, Rouadi, P W, Samolinski, B, Sastre, J, Savouré, M, Scichilone, N, Shamji, M H, Sheikh, A, Siroux, V, Sousa-Pinto, B, Standl, M, Sunyer, J, Taborda-Barata, L, Toppila-Salmi, S, Torres, M J, Tsiligianni, I, Valovirta, E, Vandenplas, O, Ventura, M T, Weiss, S, Yorgancioglu, A, Zhang, L, Abdul Latiff, A H, Aberer, W, Agache, I, Al-Ahmad, M, Alobid, I, Arshad, H S, Asayag, E, Baharudin, A, Battur, L, Bennoor, K S, Berghea, E C, Bergmann, K C, Bernstein, D, Bewick, Michael, Blain, H, Bonini, M, Braido, F, Buhl, R, Bumbacea, R, Bush, A, Calderon, M, Calvo, G, Camargos, P, Caraballo, L, Cardona, V, Carr, W, Carreiro-Martins, P, Casale, T, Cepeda Sarabia, A M, Chandrasekharan, R, Charpin, D, Chen, Y Z, Cherrez-Ojeda, I, Chivato, T, Chkhartishvili, E, Christoff, G, Chu, D K, Cingi, C, Correia da Sousa, J, Corrigan, C, Custovic, A, D'Amato, G, Del Giacco, S, De Blay, F, Devillier, P, Didier, A, do Ceu Teixeira, M, Dokic, D, Douagui, H, Doulaptsi, M, Durham, S, Dykewicz, M, Eiwegger, T, El-Sayed, Z A, Emuzyte, R, Fiocchi, A, Fyhrquist, N, Gomez, R M, Gotua, M, Guzman, M A, Hagemann, J, Hamamah, S, Halken, S, Halpin, D M G, Hofmann, M, Hossny, E, Hrubiško, M, Irani, C, Ispayeva, Z, Jares, E, Jartti, T, Jassem, E, Julge, K, Just, J, Jutel, M, Kaidashev, I, Kalayci, O, Kalyoncu, O, Kardas, P, Kirenga, B, Kraxner, H, Kull, I, Kulus, M, La Gruta, S, Lau, S, Le Tuyet Thi, L, Levin, M, Lipworth, B, Lourenço, O, Mahboub, B, Mäkelä, M J, Martinez-Infante, E, Matricardi, P, Miculinic, N, Migueres, N, Mihaltan, F, Mohamad, Y, Moniusko, M, Montefort, S, Neffen, H, Nekam, K, Nunes, E, Nyembue Tshipukane, D, O'Hehir, R E, Ogulur, I, Ohta, K, Okubo, K, Ouedraogo, S, Olze, H, Pali-Schöll, I, Palomares, O, Palosuo, K, Panaitescu, C, Panzner, P, Park, H S, Pitsios, C, Plavec, D, Popov, T A, Puggioni, F, Quirce, S, Recto, M, Repka-Ramirez, R, Roballo-Cordeiro, C, Roche, N, Rodriguez-Gonzales, M, Romantowski, J, Rosario Filho, N, Rottem, M, Sagara, H, Sarquis-Serpa, F, Sayah, Z, Scheire, S, Schmid-Grendelmeier, P, Sisul, J C, Sole, D, Soto-Martinez, M, Sova, M, Sperl, A, Spranger, O, Stelmach, R, Suppli Ulrik, C, Thomas, M, To, T, Todo-Bom, A, Tomazic, P V, Urrutia-Pereira, M, Valentin-Rostan, M, van Ganse, E, Van Hage, M, Vasankari, T, Vichyanond, P, Viegi, G, Wallace, D, Wang, D Y, Williams, S, Worm, M, Yiallouros, P, Yusuf, O, Zaitoun, F, Zernotti, M, Zidarn, M, Zuberbier, J, Fonseca, J A, Zuberbier, T, and Anto, J M
Abstract: Asthma, rhinitis and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of "one-airway-one-disease", coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhinitis and its Impact on Asthma (ARIA), (ii) new insights into polysensitisation and multimorbidity, (iii) advances in mHealth for novel phenotype definition, (iv) confirmation in canonical epidemiologic studies, (v) genomic findings, (vi) treatment approaches and (vii) novel concepts on the onset of rhinitis and multimorbidity. One recent concept, bringing together upper- and lower-airway allergic diseases with skin, gut and neuropsychiatric multimorbidities, is the "Epithelial Barrier Hypothesis". This review determined that the "one-airway-one-disease" concept does not always hold true and that several phenotypes of disease can be defined. These phenotypes include an extreme "allergic" (asthma) phenotype combining asthma, rhinitis and conjunctivitis. Rhinitis alone and rhinitis and asthma multimorbidity represent two distinct diseases with the following differences: (i) genomic and transcriptomic background (Toll-Like Receptors and IL-17 for rhinitis alone as a local disease; IL-33 and IL-5 for allergic and non-allergic multimorbidity as a systemic disease), (ii) allergen sensitisation patterns (mono- or pauci-sensitisation versus polysensitisation), (iii) severity of symptoms and (iv) treatment response. In conclusion, rhinitis alone (local disease) and rhinitis with asthma multimorbidity (systemic disease) should be considered as two distinct diseases, possibly modulated by the microbiome, and may be a model for understanding the epidemics of chronic and auto-immune diseases. [Abstract copyright: This article is protected by copyright. All rights reserved.]
Published: 2023

4. Rhinitis associated with asthma is distinct from rhinitis alone: The ARIA‐MeDALL hypothesis

Author: Bousquet, J., primary, Melén, E., additional, Haahtela, T., additional, Koppelman, G. H., additional, Togias, A., additional, Valenta, R., additional, Akdis, C. A., additional, Czarlewski, W., additional, Rothenberg, M., additional, Valiulis, A., additional, Wickman, M., additional, Akdis, M., additional, Aguilar, D., additional, Bedbrook, A., additional, Bindslev‐Jensen, C., additional, Bosnic‐Anticevich, S., additional, Boulet, L. P., additional, Brightling, C. E., additional, Brussino, L., additional, Burte, E., additional, Bustamante, M., additional, Canonica, G. W., additional, Cecchi, L., additional, Celedon, J. C., additional, Chaves Loureiro, C., additional, Costa, E., additional, Cruz, A. A., additional, Erhola, M., additional, Gemicioglu, B., additional, Fokkens, W. J., additional, Garcia‐Aymerich, J., additional, Guerra, S., additional, Heinrich, J., additional, Ivancevich, J. C., additional, Keil, T., additional, Klimek, L., additional, Kuna, P., additional, Kupczyk, M., additional, Kvedariene, V., additional, Larenas‐Linnemann, D. E., additional, Lemonnier, N., additional, Lodrup Carlsen, K. C., additional, Louis, R., additional, Makela, M., additional, Makris, M., additional, Maurer, M., additional, Momas, I., additional, Morais‐Almeida, M., additional, Mullol, J., additional, Naclerio, R. N., additional, Nadeau, K., additional, Nadif, R., additional, Niedoszytko, M., additional, Okamoto, Y., additional, Ollert, M., additional, Papadopoulos, N. G., additional, Passalacqua, G., additional, Patella, V., additional, Pawankar, R., additional, Pham‐Thi, N., additional, Pfaar, O., additional, Regateiro, F. S., additional, Ring, J., additional, Rouadi, P. W., additional, Samolinski, B., additional, Sastre, J., additional, Savouré, M., additional, Scichilone, N., additional, Shamji, M. H., additional, Sheikh, A., additional, Siroux, V., additional, Sousa‐Pinto, B., additional, Standl, M., additional, Sunyer, J., additional, Taborda‐Barata, L., additional, Toppila‐Salmi, S., additional, Torres, M. J., additional, Tsiligianni, I., additional, Valovirta, E., additional, Vandenplas, O., additional, Ventura, M. T., additional, Weiss, S., additional, Yorgancioglu, A., additional, Zhang, L., additional, Abdul Latiff, A. H., additional, Aberer, W., additional, Agache, I., additional, Al‐Ahmad, M., additional, Alobid, I., additional, Ansotegui, I. J., additional, Arshad, S. H., additional, Asayag, E., additional, Barbara, C., additional, Baharudin, A., additional, Battur, L., additional, Bennoor, K. S., additional, Berghea, E. C., additional, Bergmann, K. C., additional, Bernstein, D., additional, Bewick, M., additional, Blain, H., additional, Bonini, M., additional, Braido, F., additional, Buhl, R., additional, Bumbacea, R. S., additional, Bush, A., additional, Calderon, M., additional, Calvo‐Gil, M., additional, Camargos, P., additional, Caraballo, L., additional, Cardona, V., additional, Carr, W., additional, Carreiro‐Martins, P., additional, Casale, T., additional, Cepeda Sarabia, A. M., additional, Chandrasekharan, R., additional, Charpin, D., additional, Chen, Y. Z., additional, Cherrez‐Ojeda, I., additional, Chivato, T., additional, Chkhartishvili, E., additional, Christoff, G., additional, Chu, D. K., additional, Cingi, C., additional, Correia de Sousa, J., additional, Corrigan, C., additional, Custovic, A., additional, D’Amato, G., additional, Del Giacco, S., additional, De Blay, F., additional, Devillier, P., additional, Didier, A., additional, do Ceu Teixeira, M., additional, Dokic, D., additional, Douagui, H., additional, Doulaptsi, M., additional, Durham, S., additional, Dykewicz, M., additional, Eiwegger, T., additional, El‐Sayed, Z. A., additional, Emuzyte, R., additional, Fiocchi, A., additional, Fyhrquist, N., additional, Gomez, R. M., additional, Gotua, M., additional, Guzman, M. A., additional, Hagemann, J., additional, Hamamah, S., additional, Halken, S., additional, Halpin, D. M. G., additional, Hofmann, M., additional, Hossny, E., additional, Hrubiško, M., additional, Irani, C., additional, Ispayeva, Z., additional, Jares, E., additional, Jartti, T., additional, Jassem, E., additional, Julge, K., additional, Just, J., additional, Jutel, M., additional, Kaidashev, I., additional, Kalayci, O., additional, Kalyoncu, A. F., additional, Kardas, P., additional, Kirenga, B., additional, Kraxner, H., additional, Kull, I., additional, Kulus, M., additional, La Grutta, S., additional, Lau, S., additional, Le Tuyet Thi, L., additional, Levin, M., additional, Lipworth, B., additional, Lourenço, O., additional, Mahboub, B., additional, Martinez‐Infante, E., additional, Matricardi, P., additional, Miculinic, N., additional, Migueres, N., additional, Mihaltan, F., additional, Mohammad, Y., additional, Moniuszko, M., additional, Montefort, S., additional, Neffen, H., additional, Nekam, K., additional, Nunes, E., additional, Nyembue Tshipukane, D., additional, O’Hehir, R., additional, Ogulur, I., additional, Ohta, K., additional, Okubo, K., additional, Ouedraogo, S., additional, Olze, H., additional, Pali‐Schöll, I., additional, Palomares, O., additional, Palosuo, K., additional, Panaitescu, C., additional, Panzner, P., additional, Park, H. S., additional, Pitsios, C., additional, Plavec, D., additional, Popov, T. A., additional, Puggioni, F., additional, Quirce, S., additional, Recto, M., additional, Repka‐Ramirez, M. S., additional, Robalo Cordeiro, C., additional, Roche, N., additional, Rodriguez‐Gonzalez, M., additional, Romantowski, J., additional, Rosario Filho, N., additional, Rottem, M., additional, Sagara, H., additional, Serpa, F. S., additional, Sayah, Z., additional, Scheire, S., additional, Schmid‐Grendelmeier, P., additional, Sisul, J. C., additional, Sole, D., additional, Soto‐Martinez, M., additional, Sova, M., additional, Sperl, A., additional, Spranger, O., additional, Stelmach, R., additional, Suppli Ulrik, C., additional, Thomas, M., additional, To, T., additional, Todo‐Bom, A., additional, Tomazic, P. V., additional, Urrutia‐Pereira, M., additional, Valentin‐Rostan, M., additional, Van Ganse, E., additional, van Hage, M., additional, Vasankari, T., additional, Vichyanond, P., additional, Viegi, G., additional, Wallace, D., additional, Wang, D. Y., additional, Williams, S., additional, Worm, M., additional, Yiallouros, P., additional, Yusuf, O., additional, Zaitoun, F., additional, Zernotti, M., additional, Zidarn, M., additional, Zuberbier, J., additional, Fonseca, J. A., additional, Zuberbier, T., additional, and Anto, J. M., additional
Published: 2023
Full Text: View/download PDF

5. The ARIA-MeDALL hypothesis

Author: Bousquet, J, Melén, E, Haahtela, T, Koppelman, G H, Togias, A, Valenta, R, Akdis, C A, Czarlewski, W, Rothenberg, M, Valiulis, A, Wickmann, M, Bonini, M, Braido, F, Buhl, R, Bumbacea, R, Bush, A, Calderon, M, Calvo, G, Camargos, P, Caraballo, L, Cardona, V, Aguilar, D, Carr, W, Carreiro-Martins, P, Casale, T, Cepeda Sarabia, A M, Chandrasekharan, R, Charpin, D, Chen, Y Z, Cherrez-Ojeda, I, Chivato, T, Chkhartishvili, E, Akdis, M, Christoff, G, Chu, D K, Cingi, C, Correia da Sousa, J, Corrigan, C, Custovic, A, D'Amato, G, Del Giacco, S, De Blay, F, Devillier, P, Ansotegui, I J, Didier, A, do Ceu Teixeira, M, Dokic, D, Douagui, H, Doulaptsi, M, Durham, S, Dykewicz, M, Eiwegger, T, El-Sayed, Z A, Emuzyte, R, Barbara, C, Fiocchi, A, Fyhrquist, N, Gomez, R M, Gotua, M, Guzman, M A, Hagemann, J, Hamamah, S, Halken, S, Halpin, D M G, Bedbrook, A, Hofmann, M, Hossny, E, Hrubiško, M, Irani, C, Ispayeva, Z, Jares, E, Jartti, T, Jassem, E, Julge, K, Just, J, Bindslev Jensen, C, Jutel, M, Kaidashev, I, Kalayci, O, Kalyoncu, O, Kardas, P, Kirenga, B, Kraxner, H, Kull, I, Kulus, M, La Gruta, S, Bosnic-Anticevich, S, Lau, S, Le Tuyet Thi, L, Levin, M, Lipworth, B, Lourenço, O, Mahboub, B, Mäkelä, M J, Martinez-Infante, E, Matricardi, P, Miculinic, N, Boulet, L P, Migueres, N, Mihaltan, F, Mohamad, Y, Moniusko, M, Montefort, S, Neffen, H, Nekam, K, Nunes, E, Nyembue Tshipukane, D, O'Hehir, R E, Brightling, C E, Ogulur, I, Ohta, K, Okubo, K, Ouedraogo, S, Olze, H, Pali-Schöll, I, Palomares, O, Palosuo, K, Panaitescu, C, Panzner, P, Brussino, L, Park, H S, Pitsios, C, Plavec, D, Popov, T A, Puggioni, F, Quirce, S, Recto, M, Repka-Ramirez, R, Roballo-Cordeiro, C, Roche, N, Burte, E, Rodriguez-Gonzales, M, Romantowski, J, Rosario Filho, N, Rottem, M, Sagara, H, Sarquis-Serpa, F, Sayah, Z, Scheire, S, Schmid-Grendelmeier, P, Sisul, J C, Bustamante, M, Sole, D, Soto-Martinez, M, Sova, M, Sperl, A, Spranger, O, Stelmach, R, Suppli Ulrik, C, Thomas, M, To, T, Todo-Bom, A, Canonica, G W, Tomazic, P V, Urrutia-Pereira, M, Valentin-Rostan, M, van Ganse, E, Van Hage, M, Vasankari, T, Vichyanond, P, Viegi, G, Wallace, D, Wang, D Y, Cecchi, L, Williams, S, Worm, M, Yiallouros, P, Yusuf, O, Zaitoun, F, Zernotti, M, Zidarn, M, Zuberbier, J, Fonseca, J A, Celedon, J C, Zuberbier, T, Anto, J M, Chaves-Loureiro, C, Costa, E, Cruz, A A, Erhola, M, Gemicioglu, B, Fokkens, W J, Garcia Aymerich, J, Guerra, S, Heinrich, J, Ivancevich, J C, Keil, T, Klimek, L, Kuna, P, Kupczyk, M, Kvedariene, V, Larenas-Linnemann, D E, Lemonnier, N, Lodrup Carlsen, K C, Louis, R, Makris, M, Maurer, M, Momas, I, Morais-Almeida, M, Mullol, J, Naclerio, R N, Nadeau, K, Nadif, R, Niedoszytko, M, Okamoto, Y, Ollert, M, Papadopoulos, N G, Passalacqua, G, Patella, V, Pawankar, R, Pham-Thi, N, Pfaar, O, Regateiro, F S, Ring, J, Rouadi, P W, Samolinski, B, Sastre, J, Savouré, M, Scichilone, N, Shamji, M H, Sheikh, A, Siroux, V, Sousa-Pinto, B, Standl, M, Sunyer, J, Taborda-Barata, L, Toppila-Salmi, S, Torres, M J, Tsiligianni, I, Valovirta, E, Vandenplas, O, Ventura, M T, Weiss, S, Yorgancioglu, A, Zhang, L, Abdul Latiff, A H, Aberer, W, Agache, I, Al-Ahmad, M, Alobid, I, Arshad, H S, Asayag, E, Baharudin, A, Battur, L, Bennoor, K S, Berghea, E C, Bergmann, K C, Bernstein, D, Bewick, M, Blain, H, UCIBIO - Applied Molecular Biosciences Unit, Comprehensive Health Research Centre (CHRC) - pólo NMS, and NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
Subjects: SDG 3 - Good Health and Well-being
Abstract: Asthma, rhinitis and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of "one-airway-one-disease", coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhinitis and its Impact on Asthma (ARIA), (ii) new insights into polysensitisation and multimorbidity, (iii) advances in mHealth for novel phenotype definition, (iv) confirmation in canonical epidemiologic studies, (v) genomic findings, (vi) treatment approaches and (vii) novel concepts on the onset of rhinitis and multimorbidity. One recent concept, bringing together upper- and lower-airway allergic diseases with skin, gut and neuropsychiatric multimorbidities, is the "Epithelial Barrier Hypothesis". This review determined that the "one-airway-one-disease" concept does not always hold true and that several phenotypes of disease can be defined. These phenotypes include an extreme "allergic" (asthma) phenotype combining asthma, rhinitis and conjunctivitis. Rhinitis alone and rhinitis and asthma multimorbidity represent two distinct diseases with the following differences: (i) genomic and transcriptomic background (Toll-Like Receptors and IL-17 for rhinitis alone as a local disease; IL-33 and IL-5 for allergic and non-allergic multimorbidity as a systemic disease), (ii) allergen sensitisation patterns (mono- or pauci-sensitisation versus polysensitisation), (iii) severity of symptoms and (iv) treatment response. In conclusion, rhinitis alone (local disease) and rhinitis with asthma multimorbidity (systemic disease) should be considered as two distinct diseases, possibly modulated by the microbiome, and may be a model for understanding the epidemics of chronic and auto-immune diseases. authorsversion epub_ahead_of_print
Published: 2023

6. Multiscale Carbonate Stratigraphic and Reservoir Calibration for Mk Field in Central Luconia Province

Author: Grisel Jiménez Soto, Abdul Latiff, A. H., Hermana Husen, M., Bing Bing, S., and Wiyono, J.
Published: 2022
Full Text: View/download PDF

7. Is diet partly responsible for differences in COVID-19 death rates between and within countries?

Author: Bousquet J., Anto J. M., Iaccarino G., Czarlewski W., Haahtela T., Anto A., Akdis C. A., Blain H., Canonica G. W., Cardona V., Cruz A. A., Illario M., Ivancevich J. C., Jutel M., Klimek L., Kuna P., Laune D., Larenas-Linnemann D., Mullol J., Papadopoulos N. G., Pfaar O., Samolinski B., Valiulis A., Yorgancioglu A., Zuberbier T., Abdul Latiff A. H., Abdullah B., Aberer W., Abusada N., Adcock I., Afani A., Agache I., Aggelidis X., Agustin J., Akdis C., Akdis M., Al-Ahmad M., Al-Zahab Bassam A., Aldrey-Palacios O., Alvarez Cuesta E., Alzaabi A., Amad S., Ambrocio G., Annesi-Maesano I., Ansotegui I., Anto J., Arshad H., Artesani M. C., Asayag E., Avolio F., Azhari K., Baiardini I., Bajrovic N., Bakakos P., Bakeyala Mongono S., Balotro-Torres C., Barba S., Barbara C., Barbosa E., Barreto B., Bartra J., Bateman E. D., Battur L., Bedbrook A., Bedolla Barajas M., Beghe B., Bel E., Ben Kheder A., Benson M., Berghea C., Bergmann K. -C., Bernstein D., Bewick M., Bialek S., Bialoszewski A., Bieber T., Billo N., Bilo M. B., Bindslev-Jensen C., Bjermer L., Bochenska Marciniak M., Bond C., Boner A., Bonini M., Bonini S., Bosnic-Anticevich S., Bosse I., Botskariova S., Bouchard J., Boulet L. -P., Bourret R., Bousquet P., Braido F., Briggs A., Brightling C., Brozek J., Buhl R., Bumbacea R., Burguete Cabanas M. T., Bush A., Busse W. W., Buters J., Caballero-Fonseca F., Calderon M. A., Calvo M., Camargos P., Camuzat T., Cano A., Capriles-Hulett A., Caraballo L., Carlsen K. -H., Caro J., Carr W., Carreon-Asuncion F., Carriazo A. M., Casale T., Castor M. A., Castro E., Cecchi L., Cepeda Sarabia A., Chandrasekharan R., Chang Y. -S., Chato-Andeza V., Chatzi L., Chatzidaki C., Chavannes N. H., Chen Y., Cheng L., Chivato T., Chkhartishvili E., Christoff G., Chrystyn H., Chu D. K., Chua A., Chuchalin A., Chung K. F., Ciceran A., Cingi C., Ciprandi G., Cirule I., Coelho A. C., Constantinidis J., Correia De Sousa J., Costa E., Costa D., Costa Dominguez M. D. C., Coste A., Cox L., Cullen J., Custovic A., Cvetkovski B., D'Amato G., Da Silva J., Dahl R., Dahlen S. -E., Daniilidis V., Darjazini Nahhas L., Darsow U., De Blay F., De Guia E., De Los Santos C., De Manuel Keenoy E., De Vries G., Deleanu D., Demoly P., Denburg J., Devillier P., Didier A., Dimou M., Dinh-Xuan A. T., Djukanovic R., Dokic D., Dominguez Silva M. G., Douagui H., Douladiris N., Doulaptsi M., Dray G., Dubakiene R., Durham S., Dykewicz M., Ebo D., Edelbaher N., Eklund P., El-Gamal Y., El-Sayed Z. A., El-Sayed S. S., El-Seify M., Emuzyte R., Enecilla L., Espinoza H., Espinoza Contreras J. G., Farrell J., Fernandez L., Fink Wagner A., Fiocchi A., Fokkens W. J., Fontaine J. -F., Forastiere F., Fuentes Perez J. M., Gaerlan-Resureccion E., Gaga M., Galvez Romero J. L., Gamkrelidze A., Garcia A., Garcia Cobas C. Y., Garcia Cruz M. D. L. L. H., Gayraud J., Gemicioglu B., Genova S., Gereda J., Gerth Van Wijk R., Gomez M., Gonzalez Diaz S., Gotua M., Grigoreas C., Grisle I., Guidacci M., Guldemond N., Gutter Z., Guzman A., Halloum R., Hamelmann E., Hammadi S., Harvey R., Heinrich J., Hejjaoui A., Hellquist-Dahl B., Hernandez Velazquez L., Hew M., Hossny E., Howarth P., Hrubisko M., Huerta Villalobos Y. R., Humbert M., Hyland M., Ibrahim M., Ilyina N., Irani C., Ispayeva Z., Jares E., Jarvis D., Jassem E., Jenko K., Jimeneracruz Uscanga R. D., Johnston S., Joos G., Jost M., Julge K., Jung K. -S., Just J., Kaidashev I., Kalayci O., Kalyoncu F., Kapsali J., Kardas P., Karjalainen J., Kasala C. A., Katotomichelakis M., Kazi B., Keil T., Keith P., Khaitov M., Khaltaev N., Kim Y. -Y., Kleine-Tebbe J., Koffi N'Goran B., Kompoti E., Kopac P., Koppelman G., Koren Jeverica A., Kosnik M., Kostov K. V., Kowalski M. L., Kralimarkova T., Kramer Vrscaj K., Kraxner H., Kreft S., Kritikos V., Kudlay D., Kull I., Kupczyk M., Kvedariene V., Kyriakakou M., Lalek N., Lane S., Latiff A., Lau S., Lavrut J., Le L., Lessa M., Levin M., Li J., Lieberman P., Liotta G., Lipworth B., Liu X., Lobo R., Lodrup Carlsen K. C., Lombardi C., Louis R., Loukidis S., Lourenco O., Luna Pech J. A., Madjar B., Magnan A., Mahboub B., Mair A., Mais Y., Maitland Van Der Zee A. -H., Makela M., Makris M., Malling H. -J., Mandajieva M., Manning P., Manousakis M., Maragoudakis P., Marshall G., Martinsmartins P., Masjedi M. R., Maspero J. F., Matta Campos J. J., Maurer M., Mavale-Manuel S., Meco C., Melen E., Melo-Gomes E., Meltzer E. O., Menditto E., Menzies-Gow A., Merk H., Michel J. -P., Miculinic N., Midao L., Mihaltan F., Mikael K., Mikos N., Milenkovic B., Mitsias D., Moalla B., Moda G., Mogica Martinez M. D., Mohammad Y., Moin M., Molimard M., Momas I., Monaco A., Montefort S., Mora D., Morais-Almeida M., Mosges R., Mostafa B. E., Munter L., Muraro A., Murray R., Mustakov T., Naclerio R., Nadif R., Nakonechna A., Namazova-Baranova L., Navarro-Locsin G., Neffen H., Nekam K., Neou A., Nicod L., Niederberger-Leppin V., Niedoszytko M., Nieto A., Novellino E., Nunes E., Nyembue D., O'Hehir R., Odjakova C., Ohta K., Okamoto Y., Okubo K., Oliver B., Onorato G. L., Orru M. P., Ouedraogo S., Ouoba K., Paggiaro P. L., Pagkalos A., Palaniappan S. P., Pali-Scholl I., Palkonen S., Palmer S., Panaitescu Bunu C., Panzner P., Papanikolaou V., Papi A., Paralchev B., Paraskevopoulos G., Park H. S., Passalacqua G., Patella V., Pavord I., Pawankar R., Pedersen S., Peleve S., Pereira A., Perez T., Pham-Thi N., Pigearias B., Pin I., Piskou K., Pitsios C., Pitsios K., Plavec D., Poethig D., Pohl W., Poplas Susic A., Popov T. A., Portejoie F., Potter P., Poulsen L., Prados-Torres A., Prarros F., Price D., Prokopakis E., Puy R., Rabe K., Raciborski F., Ramos J., Recto M. T., Reda S. M., Regateiro F., Reider N., Reitsma S., Repka-Ramirez S., Rimmer J., Rivero Yeverino D., Rizzo J. A., Robalo-Cordeiro C., Roberts G., Roche N., Rodriguez Gonzalez M., Rodriguez Zagal E., Rolland C., Roller-Wirnsberger R., Roman Rodriguez M., Romano A., Rombaux P., Romualdez J., Rosado-Pinto J., Rosario N., Rosenwasser L., Rottem M., Rouadi P., Rovina N., Rozman Sinur I., Ruiz M., Ruiz Segura L. T., Ryan D., Sagara H., Sakai D., Sakurai D., Saleh W., Salimaki J., Salina H., Samitas K., Sanchez Coronel M. G., Sanchez-Borges M., Sanchez-Lopez J., Sarafoleanu C., Sarquis Serpa F., Sastre-Dominguez J., Scadding G., Scheire S., Schmid-Grendelmeier P., Schuhl J. F., Schunemann H., Schvalbova M., Scichilone N., Sepulveda C., Serrano E., Sheikh A., Shields M., Shishkov V., Siafakas N., Simeonov A., Simons E. F., Sisul J. C., Sitkauskiene B., Skrindo I., Soklic Kosak T., Sole D., Sooronbaev T., Soto-Martinez M., Sova M., Spertini F., Spranger O., Stamataki S., Stefanaki L., Stellato C., Stelmach R., Sterk P., Strandberg T., Stute P., Subramaniam A., Suppli Ulrik C., Sutherland M., Sylvestre S., Syrigou A., Taborda Barata L., Takovska N., Tan R., Tan F., Tan V., Tang I. P., Taniguchi M., Tannert L., Tattersall J., Teixeira M. D. C., Thijs C., Thomas M., To T., Todo-Bom A. M., Togias A., Tomazic P. -V., Toppila-Salmi S., Toskala E., Triggiani M., Triller N., Triller K., Tsiligianni I., Ulmeanu R., Urbancic J., Urrutia Pereira M., Vachova M., Valdes F., Valenta R., Valentin Rostan M., Valero A., Vallianatou M., Valovirta E., Van Eerd M., Van Ganse E., Van Hage M., Vandenplas O., Vasankari T., Vassileva D., Ventura M. T., Vera-Munoz C., Vicheva D., Vichyanond P., Vidgren P., Viegi G., Vogelmeier C., Von Hertzen L., Vontetsianos T., Vourdas D., Wagenmann M., Walker S., Wallace D., Wang D. Y., Waserman S., Wickman M., Williams S., Williams D., Wilson N., Woo K., Wright J., Wroczynski P., Xepapadaki P., Yakovliev P., Yamaguchi M., Yan K., Yap Y. Y., Yawn B., Yiallouros P., Yoshihara S., Young I., Yusuf O. B., Zaidi A., Zaitoun F., Zar H., Zernotti M., Zhang L., Zhong N., Zidarn M., Zubrinich C., UCL - (MGD) Service de pneumologie, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, Bousquet J., Anto J.M., Iaccarino G., Czarlewski W., Haahtela T., Anto A., Akdis C.A., Blain H., Canonica G.W., Cardona V., Cruz A.A., Illario M., Ivancevich J.C., Jutel M., Klimek L., Kuna P., Laune D., Larenas-linnemann D., Mullol J., Papadopoulos N.G., Pfaar O., Samolinski B., Valiulis A., Yorgancioglu A., Zuberbier T., Abdul Latiff A.H., Abdullah B., Aberer W., Abusada N., Adcock I., Afani A., Agache I., Aggelidis X., Agustin J., Akdis C., Akdis M., Al-Ahmad M., Bassam A.A.-Z., Aldrey-Palacios O., Cuesta E.A., Alzaabi A., Amad S., Ambrocio G., Annesi-Maesano I., Ansotegui I., Anto J., Arshad H., Artesani M.C., Asayag E., Avolio F., Azhari K., Baiardini I., Bajrovic N., Bakakos P., Mongono S.B., Balotro-Torres C., Barba S., Barbara C., Barbosa E., Barreto B., Bartra J., Bateman E.D., Battur L., Bedbrook A., Barajas M.B., Beghe B., Bel E., Kheder A.B., Benson M., Berghea C., Bergmann K.-C., Bernstein D., Bewick M., Bialek S., Bialoszewski A., Bieber T., Billo N., Bilo M.B., Bindslev-Jensen C., Bjermer L., Marciniak M.B., Bond C., Boner A., Bonini M., Bonini S., Bosnic-Anticevich S., Bosse I., Botskariova S., Bouchard J., Boulet L.-P., Bourret R., Bousquet P., Braido F., Briggs A., Brightling C., Brozek J., Buhl R., Bumbacea R., Cabanas M.T.B., Bush A., Busse W.W., Buters J., Caballero-Fonseca F., Calderon M.A., Calvo M., Camargos P., Camuzat T., Cano A., Capriles-Hulett A., Caraballo L., Carlsen K.-H., Caro J., Carr W., Carreon-Asun-cion F., Carriazo A.M., Casale T., Castor M.A., Castro E., Cecchi L., Sarabia A.C., Chandrasekharan R., Chang Y.-S., Chato-Andeza V., Chatzi L., Chatzidaki C., Chavannes N.H., Chen Y., Cheng L., Chivato T., Chkhartishvili E., Christoff G., Chrystyn H., Chu D.K., Chua A., Chuchalin A., Chung K.F., Ciceran A., Cingi C., Ciprandi G., Cirule I., Coelho A.C., Constantinidis J., de Sousa J.C., Costa E., Costa D., Dominguez M.C.C., Coste A., Cox L., Cullen J., Custovic A., Cvetkovski B., D'amato G., Silva J.D., Dahl R., Dahlen S.-E., Daniilidis V., Nahhas L.D., Darsow U., Blay F., Guia E.D., Santos C., Keenoy E.D.M., Vries G.D., Deleanu D., Demoly P., Denburg J., Devillier P., Didier A., Dimou M., Dinh-Xuan A.T., Djukanovic R., Dokic D., Dominguez Silva M.G., Douagui H., Douladiris N., Doulaptsi M., Dray G., Dubakiene R., Durham S., Dykewicz M., Ebo D., Edelbaher N., Eklund P., El-Gamal Y., El-Sayed Z.A., El-Sayed S.S., El-Seify M., Emuzyte R., Enecilla L., Espinoza H., Guillermo J., Contreras E., Farrell J., Fernandez L., Wagner A.F., Fiocchi A., Fokkens W.J., Fontaine J.-F., Forastiere F., Perez J.M.F., Gaerlan-resureccion E., Gaga M., Romero J.L.G., Gamkrelidze A., Garcia A., Cobas C.Y.G., Garcia Cruz M.L.L.H., Gayraud J., Gemicioglu B., Genova S., Gereda J., Wijk R.G., Gomez M., Diaz S.G., Gotua M., Grigoreas C., Grisle I., Guidacci M., Guldemond N., Gutter Z., Guzman A., Halloum R., Hamelmann E., Hammadi S., Harvey R., Heinrich J., Hejjaoui A., Hellquist-Dahl B., Velazquez L.H., Hew M., Hossny E., Howarth P., Hrubisko M., Villalobos Y.R.H., Humbert M., Hyland M., Ibrahim M., Ilyina N., Irani C., Ispayeva Z., Jares E., Jarvis D., Jassem E., Jenko K., Uscanga R.D.J., Johnston S., Joos G., Jost M., Julge K., Jung K.-S., Just J., Kaidashev I., Kalayci O., Kalyoncu F., Kapsali J., Kardas P., Karjalainen J., Kasala C.A., Katotomichelakis M., Kazi B., Keil T., Keith P., Khaitov M., Khaltaev N., Kim Y.-Y., Kleine-Tebbe J., Koffi N'Goran B., Kompoti E., Kopac P., Koppelman G., Jeverica A.K., Kosnik M., Kostov K.V., Kowalski M.L., Kralimarkova T., Vrscaj K.K., Kraxner H., Kreft S., Kritikos V., Kudlay D., Kull I., Kupczyk M., Kvedariene V., Kyriakakou M., Lalek N., Lane S., Larenas-Linnemann D., Latiff A., Lau S., Lavrut J., Le L., Lessa M., Levin M., Li J., Lieberman P., Liotta G., Lipworth B., Liu X., Lobo R., Lodrup Carlsen K.C., Lombardi C., Louis R., Loukidis S., Lourenco O., Luna Pech J.A., Madjar B., Magnan A., Mahboub B., Mair A., Mais Y., van der Zee A.-H.M., Makela M., Makris M., Malling H.-J., Mandajieva M., Manning P., Manousakis M., Maragoudakis P., Marshall G., Martins P., Reza Masjedi M., Maspero J.F., Campos J.J.M., Maurer M., Mavale-Manuel S., Meco C., Melen E., Melo-Gomes E., Meltzer E.O., Menditto E., Menzies-Gow A., Merk H., Michel J.-P., Miculinic N., Midao L., Mihaltan F., Mikael K., Mikos N., Milenkovic B., Mitsias D., Moalla B., Moda G., Martinez M.D.M., Mohammad Y., Moin M., Molimard M., Momas I., Monaco A., Montefort S., Mora D., Morais-Almeida M., Mosges R., Mostafa B.E., Munter L., Muraro A., Murray R., Mustakov T., Naclerio R., Nadif R., Nakonechna A., Namazova-Baranova L., Navarro-Locsin G., Neffen H., Nekam K., Neou A., Nicod L., Niederberger-Leppin V., Niedoszytko M., Nieto A., Novellino E., Nunes E., Nyembue D., O'hehir R., Odjakova C., Ohta K., Okamoto Y., Okubo K., Oliver B., Onorato G.L., Orru M.P., Ouedraogo S., Ouoba K., Paggiaro P.L., Pagkalos A., Palaniappan S.P., Pali-Scholl I., Palkonen S., Palmer S., Bunu C.P., Panzner P., Papanikolaou V., Papi A., Paralchev B., Paraskevopoulos G., Park H.S., Passalacqua G., Patella V., Pavord I., Pawankar R., Pedersen S., Peleve S., Pereira A., Perez T., Pham-Thi N., Pigearias B., Pin I., Piskou K., Pitsios C., Pitsios K., Plavec D., Poethig D., Pohl W., Susic A.P., Popov T.A., Portejoie F., Potter P., Poulsen L., Prados-Torres A., Prarros F., Price D., Prokopakis E., Puy R., Rabe K., Raciborski F., Ramos J., Recto M.T., Reda S.M., Regateiro F., Reider N., Reitsma S., Repka-Ramirez S., Rimmer J., Yeverino D.R., Rizzo J.A., Robalo-Cordeiro C., Roberts G., Roche N., Gonzalez M.R., Zagal E.R., Rolland C., Roller-Wirns-berger R., Rodriguez M.R., Romano A., Rombaux P., Romualdez J., Rosado-Pinto J., Rosario N., Rosenwasser L., Rottem M., Rouadi P., Rovina N., Sinur I.R., Ruiz M., Segura L.T.R., Ryan D., Sagara H., Sakai D., Sakurai D., Saleh W., Salimaki J., Salina H., Samitas K.-N., Coronel M.G.S., Sanchez-Borges M., Sanchez-Lopez J., Sarafoleanu C., Serpa F.S., Sastre-Dominguez J., Scadding G., Scheire S., Schmid-Grendelmeier P., Schuhl J.F., Schunemann H., Schvalbova M., Scichilone N., Sepulveda C., Serrano E., Sheikh A., Shields M., Shishkov V., Siafakas N., Simeonov A., Simons E.F., Sisul J.C., Sitkauskiene B., Skrindo I., Kosak T.S., Sole D., Sooronbaev T., Soto-Martinez M., Sova M., Spertini F., Spranger O., Stamataki S., Stefanaki L., Stellato C., Stelmach R., Sterk P., Strandberg T., Stute P., Subramaniam A., Suppli Ulrik C., Sutherland M., Sylvestre S., Syrigou A., Barata L.T., Takovska N., Tan R., Tan F., Tan V., Tang I.P., Taniguchi M., Tannert L., Tattersall J., Teixeira M.D.C., Thijs C., Thomas M., To T., Todo-Bom A.M., Togias A., Tomazic P.-V., Toppila-Salmi S., Toskala E., Triggiani M., Triller N., Triller K., Tsiligianni I., Ulmeanu R., Urbancic J., Pereira M.U., Vachova M., Valdes F., Valenta R., Rostan M.V., Valero A., Vallianatou M., Valovirta E., Eerd M.V., Ganse E.V., Hage M., Vandenplas O., Vasankari T., Vassileva D., Ventura T., Vera-Munoz C., Vicheva D., Vichyanond P., Vidgren P., Viegi G., Vogelmeier C., Hertzen L.V., Vontetsianos T., Vourdas D., Wagenmann M., Walker S., Wallace D., Wang D.Y., Waserman S., Wickman M., Williams S., Williams D., Wilson N., Woo K., Wright J., Wroczynski P., Xepapadaki P., Yakovliev P., Yamaguchi M., Yan K., Yap Y.Y., Yawn B., Yiallouros P., Yoshihara S., Young I., Yusuf O.B., Zaidi A., Zaitoun F., Zar H., Zernotti M., Zhang L., Zhong N., Zidarn M., Zubrinich C., Dubakienė, Rūta, Ėmužytė, Regina, Kvedarienė, Violeta, Bousquet, J., Anto, J. M., Iaccarino, G., Czarlewski, W., Haahtela, T., Anto, A., Akdis, C. A., Blain, H., Canonica, G. W., Cardona, V., Cruz, A. A., Illario, M., Ivancevich, J. C., Jutel, M., Klimek, L., Kuna, P., Laune, D., Larenas-Linnemann, D., Mullol, J., Papadopoulos, N. G., Pfaar, O., Samolinski, B., Valiulis, A., Yorgancioglu, A., Zuberbier, T., Abdul Latiff, A. H., Abdullah, B., Aberer, W., Abusada, N., Adcock, I., Afani, A., Agache, I., Aggelidis, X., Agustin, J., Akdis, C., Akdis, M., Al-Ahmad, M., Al-Zahab Bassam, A., Aldrey-Palacios, O., Alvarez Cuesta, E., Alzaabi, A., Amad, S., Ambrocio, G., Annesi-Maesano, I., Ansotegui, I., Anto, J., Arshad, H., Artesani, M. C., Asayag, E., Avolio, F., Azhari, K., Baiardini, I., Bajrovic, N., Bakakos, P., Bakeyala Mongono, S., Balotro-Torres, C., Barba, S., Barbara, C., Barbosa, E., Barreto, B., Bartra, J., Bateman, E. D., Battur, L., Bedbrook, A., Bedolla Barajas, M., Beghe, B., Bel, E., Ben Kheder, A., Benson, M., Berghea, C., Bergmann, K. -C., Bernstein, D., Bewick, M., Bialek, S., Bialoszewski, A., Bieber, T., Billo, N., Bilo, M. B., Bindslev-Jensen, C., Bjermer, L., Bochenska Marciniak, M., Bond, C., Boner, A., Bonini, M., Bonini, S., Bosnic-Anticevich, S., Bosse, I., Botskariova, S., Bouchard, J., Boulet, L. -P., Bourret, R., Bousquet, P., Braido, F., Briggs, A., Brightling, C., Brozek, J., Buhl, R., Bumbacea, R., Burguete Cabanas, M. T., Bush, A., Busse, W. W., Buters, J., Caballero-Fonseca, F., Calderon, M. A., Calvo, M., Camargos, P., Camuzat, T., Cano, A., Capriles-Hulett, A., Caraballo, L., Carlsen, K. -H., Caro, J., Carr, W., Carreon-Asuncion, F., Carriazo, A. M., Casale, T., Castor, M. A., Castro, E., Cecchi, L., Cepeda Sarabia, A., Chandrasekharan, R., Chang, Y. -S., Chato-Andeza, V., Chatzi, L., Chatzidaki, C., Chavannes, N. H., Chen, Y., Cheng, L., Chivato, T., Chkhartishvili, E., Christoff, G., Chrystyn, H., Chu, D. K., Chua, A., Chuchalin, A., Chung, K. F., Ciceran, A., Cingi, C., Ciprandi, G., Cirule, I., Coelho, A. C., Constantinidis, J., Correia De Sousa, J., Costa, E., Costa, D., Costa Dominguez, M. D. C., Coste, A., Cox, L., Cullen, J., Custovic, A., Cvetkovski, B., D'Amato, G., Da Silva, J., Dahl, R., Dahlen, S. -E., Daniilidis, V., Darjazini Nahhas, L., Darsow, U., De Blay, F., De Guia, E., De Los Santos, C., De Manuel Keenoy, E., De Vries, G., Deleanu, D., Demoly, P., Denburg, J., Devillier, P., Didier, A., Dimou, M., Dinh-Xuan, A. T., Djukanovic, R., Dokic, D., Dominguez Silva, M. G., Douagui, H., Douladiris, N., Doulaptsi, M., Dray, G., Dubakiene, R., Durham, S., Dykewicz, M., Ebo, D., Edelbaher, N., Eklund, P., El-Gamal, Y., El-Sayed, Z. A., El-Sayed, S. S., El-Seify, M., Emuzyte, R., Enecilla, L., Espinoza, H., Espinoza Contreras, J. G., Farrell, J., Fernandez, L., Fink Wagner, A., Fiocchi, A., Fokkens, W. J., Fontaine, J. -F., Forastiere, F., Fuentes Perez, J. M., Gaerlan-Resureccion, E., Gaga, M., Galvez Romero, J. L., Gamkrelidze, A., Garcia, A., Garcia Cobas, C. Y., Garcia Cruz, M. D. L. L. H., Gayraud, J., Gemicioglu, B., Genova, S., Gereda, J., Gerth Van Wijk, R., Gomez, M., Gonzalez Diaz, S., Gotua, M., Grigoreas, C., Grisle, I., Guidacci, M., Guldemond, N., Gutter, Z., Guzman, A., Halloum, R., Hamelmann, E., Hammadi, S., Harvey, R., Heinrich, J., Hejjaoui, A., Hellquist-Dahl, B., Hernandez Velazquez, L., Hew, M., Hossny, E., Howarth, P., Hrubisko, M., Huerta Villalobos, Y. R., Humbert, M., Hyland, M., Ibrahim, M., Ilyina, N., Irani, C., Ispayeva, Z., Jares, E., Jarvis, D., Jassem, E., Jenko, K., Jimeneracruz Uscanga, R. D., Johnston, S., Joos, G., Jost, M., Julge, K., Jung, K. -S., Just, J., Kaidashev, I., Kalayci, O., Kalyoncu, F., Kapsali, J., Kardas, P., Karjalainen, J., Kasala, C. A., Katotomichelakis, M., Kazi, B., Keil, T., Keith, P., Khaitov, M., Khaltaev, N., Kim, Y. -Y., Kleine-Tebbe, J., Koffi N'Goran, B., Kompoti, E., Kopac, P., Koppelman, G., Koren Jeverica, A., Kosnik, M., Kostov, K. V., Kowalski, M. L., Kralimarkova, T., Kramer Vrscaj, K., Kraxner, H., Kreft, S., Kritikos, V., Kudlay, D., Kull, I., Kupczyk, M., Kvedariene, V., Kyriakakou, M., Lalek, N., Lane, S., Latiff, A., Lau, S., Lavrut, J., Le, L., Lessa, M., Levin, M., Li, J., Lieberman, P., Liotta, G., Lipworth, B., Liu, X., Lobo, R., Lodrup Carlsen, K. C., Lombardi, C., Louis, R., Loukidis, S., Lourenco, O., Luna Pech, J. A., Madjar, B., Magnan, A., Mahboub, B., Mair, A., Mais, Y., Maitland Van Der Zee, A. -H., Makela, M., Makris, M., Malling, H. -J., Mandajieva, M., Manning, P., Manousakis, M., Maragoudakis, P., Marshall, G., Martinsmartins, P., Masjedi, M. R., Maspero, J. F., Matta Campos, J. J., Maurer, M., Mavale-Manuel, S., Meco, C., Melen, E., Melo-Gomes, E., Meltzer, E. O., Menditto, E., Menzies-Gow, A., Merk, H., Michel, J. -P., Miculinic, N., Midao, L., Mihaltan, F., Mikael, K., Mikos, N., Milenkovic, B., Mitsias, D., Moalla, B., Moda, G., Mogica Martinez, M. D., Mohammad, Y., Moin, M., Molimard, M., Momas, I., Monaco, A., Montefort, S., Mora, D., Morais-Almeida, M., Mosges, R., Mostafa, B. E., Munter, L., Muraro, A., Murray, R., Mustakov, T., Naclerio, R., Nadif, R., Nakonechna, A., Namazova-Baranova, L., Navarro-Locsin, G., Neffen, H., Nekam, K., Neou, A., Nicod, L., Niederberger-Leppin, V., Niedoszytko, M., Nieto, A., Novellino, E., Nunes, E., Nyembue, D., O'Hehir, R., Odjakova, C., Ohta, K., Okamoto, Y., Okubo, K., Oliver, B., Onorato, G. L., Orru, M. P., Ouedraogo, S., Ouoba, K., Paggiaro, P. L., Pagkalos, A., Palaniappan, S. P., Pali-Scholl, I., Palkonen, S., Palmer, S., Panaitescu Bunu, C., Panzner, P., Papanikolaou, V., Papi, A., Paralchev, B., Paraskevopoulos, G., Park, H. S., Passalacqua, G., Patella, V., Pavord, I., Pawankar, R., Pedersen, S., Peleve, S., Pereira, A., Perez, T., Pham-Thi, N., Pigearias, B., Pin, I., Piskou, K., Pitsios, C., Pitsios, K., Plavec, D., Poethig, D., Pohl, W., Poplas Susic, A., Popov, T. A., Portejoie, F., Potter, P., Poulsen, L., Prados-Torres, A., Prarros, F., Price, D., Prokopakis, E., Puy, R., Rabe, K., Raciborski, F., Ramos, J., Recto, M. T., Reda, S. M., Regateiro, F., Reider, N., Reitsma, S., Repka-Ramirez, S., Rimmer, J., Rivero Yeverino, D., Rizzo, J. A., Robalo-Cordeiro, C., Roberts, G., Roche, N., Rodriguez Gonzalez, M., Rodriguez Zagal, E., Rolland, C., Roller-Wirnsberger, R., Roman Rodriguez, M., Romano, A., Rombaux, P., Romualdez, J., Rosado-Pinto, J., Rosario, N., Rosenwasser, L., Rottem, M., Rouadi, P., Rovina, N., Rozman Sinur, I., Ruiz, M., Ruiz Segura, L. T., Ryan, D., Sagara, H., Sakai, D., Sakurai, D., Saleh, W., Salimaki, J., Salina, H., Samitas, K., Sanchez Coronel, M. G., Sanchez-Borges, M., Sanchez-Lopez, J., Sarafoleanu, C., Sarquis Serpa, F., Sastre-Dominguez, J., Scadding, G., Scheire, S., Schmid-Grendelmeier, P., Schuhl, J. F., Schunemann, H., Schvalbova, M., Scichilone, N., Sepulveda, C., Serrano, E., Sheikh, A., Shields, M., Shishkov, V., Siafakas, N., Simeonov, A., Simons, E. F., Sisul, J. C., Sitkauskiene, B., Skrindo, I., Soklic Kosak, T., Sole, D., Sooronbaev, T., Soto-Martinez, M., Sova, M., Spertini, F., Spranger, O., Stamataki, S., Stefanaki, L., Stellato, C., Stelmach, R., Sterk, P., Strandberg, T., Stute, P., Subramaniam, A., Suppli Ulrik, C., Sutherland, M., Sylvestre, S., Syrigou, A., Taborda Barata, L., Takovska, N., Tan, R., Tan, F., Tan, V., Tang, I. P., Taniguchi, M., Tannert, L., Tattersall, J., Teixeira, M. D. C., Thijs, C., Thomas, M., To, T., Todo-Bom, A. M., Togias, A., Tomazic, P. -V., Toppila-Salmi, S., Toskala, E., Triggiani, M., Triller, N., Triller, K., Tsiligianni, I., Ulmeanu, R., Urbancic, J., Urrutia Pereira, M., Vachova, M., Valdes, F., Valenta, R., Valentin Rostan, M., Valero, A., Vallianatou, M., Valovirta, E., Van Eerd, M., Van Ganse, E., Van Hage, M., Vandenplas, O., Vasankari, T., Vassileva, D., Ventura, M. T., Vera-Munoz, C., Vicheva, D., Vichyanond, P., Vidgren, P., Viegi, G., Vogelmeier, C., Von Hertzen, L., Vontetsianos, T., Vourdas, D., Wagenmann, M., Walker, S., Wallace, D., Wang, D. Y., Waserman, S., Wickman, M., Williams, S., Williams, D., Wilson, N., Woo, K., Wright, J., Wroczynski, P., Xepapadaki, P., Yakovliev, P., Yamaguchi, M., Yan, K., Yap, Y. Y., Yawn, B., Yiallouros, P., Yoshihara, S., Young, I., Yusuf, O. B., Zaidi, A., Zaitoun, F., Zar, H., Zernotti, M., Zhang, L., Zhong, N., Zidarn, M., Zubrinich, C., University of Zurich, Bousquet, Jean, Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], Berlin Institute of Health (BIH), Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon (MACVIA-LR), Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Universitaire de Nîmes (CHU Nîmes)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-European Innovation Partnership on Active and Healthy Ageing Reference Site (EIP on AHA), Commission Européenne-Commission Européenne-Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Center for Research in Environmental Epidemiology (CREAL), Universitat Pompeu Fabra [Barcelona] (UPF)-Catalunya ministerio de salud, IMIM-Hospital del Mar, Generalitat de Catalunya, Universitat Pompeu Fabra [Barcelona] (UPF), CIBER de Epidemiología y Salud Pública (CIBERESP), 'Federico II' University of Naples Medical School, Medical Consulting Czarlewski, Helsingin yliopisto = Helsingfors universitet = University of Helsinki, Swiss Institute of Allergy and Asthma Research (SIAF), Universität Zürich [Zürich] = University of Zurich (UZH), Euromov (EuroMov), Université de Montpellier (UM), IRCCS Humanitas Research Hospital, 20089 Rozzano, Italy., Vall d'Hebron University Hospital [Barcelona], ProAR – Nucleo de Excelencia em Asma, Universidade Federal da Bahia (UFBA), Global Alliance Against Chronic Respiratory Diseases (GARD-WHO), Division for Health Innovation, Servicio de Alergia e ImmunologiaBuenos Aires (Clinica Santa Isabel), Wrocław Medical University, Center for Rhinology and Allergology Wiesbaden, University Hospital Mannheim, Barlicki University Hospital, KYomed INNOV [Montpellier], Hospital Medica Sur [Mexico City, Mexico], Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona (UB), Centro de Investigación Biomédica en Red Enfermedades Respiratorias (CIBERES), Royal Manchester Children's Hospital, University of Manchester [Manchester], General Children's Hospital of Athens P & A Kyriakou, Philipps Universität Marburg = Philipps University of Marburg, Medical University of Warsaw - Poland, Vilnius University [Vilnius], Manisa Celal Bayar University, and Salvy-Córdoba, Nathalie
Subjects: BLOOD-PRESSURE, Review, Angiotensin-converting enzyme, Antioxidant, Coronavirus, Diet, Food, law.invention, Dietary interventions, 0302 clinical medicine, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, 10183 Swiss Institute of Allergy and Asthma Research, law, Medicine and Health Sciences, Immunology and Allergy, Medicine, 030212 general & internal medicine, [SDV.MHEP.ME] Life Sciences [q-bio]/Human health and pathology/Emerging diseases, [SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases, education.field_of_study, Mortality rate, 3. Good health, [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, 2723 Immunology and Allergy, Angiotensin-converting enzyme, Antioxidant, Coronavirus, Diet, Food, Pulmonary and Respiratory Medicine, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), Coronaviru, Immunology, Population, 610 Medicine & health, COVID-19, Settore MED/10 - Malattie Dell'Apparato Respiratorio, 03 medical and health sciences, Environmental health, population, angiotensin-converting enzyme, Quarantine, education, 2403 Immunology, ANTIHYPERTENSIVE PEPTIDES, business.industry, RC581-607, GENE, POLYMORPHISM, [SDV.AEN] Life Sciences [q-bio]/Food and Nutrition, 030228 respiratory system, 2740 Pulmonary and Respiratory Medicine, Immunologic diseases. Allergy, business, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, Regional differences, Coronavirus Infections
Abstract: Reported COVID-19 deaths in Germany are relatively low as compared to many European countries. Among the several explanations proposed, an early and large testing of the population was put forward. Most current debates on COVID-19 focus on the differences among countries, but little attention has been given to regional differences and diet. The low-death rate European countries (e.g. Austria, Baltic States, Czech Republic, Finland, Norway, Poland, Slovakia) have used different quarantine and/or confinement times and methods and none have performed as many early tests as Germany. Among other factors that may be significant are the dietary habits. It seems that some foods largely used in these countries may reduce angiotensin-converting enzyme activity or are anti-oxidants. Among the many possible areas of research, it might be important to understand diet and angiotensin-converting enzyme-2 (ACE2) levels in populations with different COVID-19 death rates since dietary interventions may be of great benefit.
Published: 2020
Full Text: View/download PDF

8. ARIA-EAACI care pathways for allergen immunotherapy in respiratory allergy

Author: Bousquet, Jean, Pfaar, Oliver, Agache, Ioana, Bedbrook, Anna, Akdis, Cezmi A.., Canonica, G. Walter, Chivato, Tomas, Al-Ahmad, Mona, Abdul Latiff, Amir H., Ansotegui, Ignacio J., Bachert, Claus, Baharuddin, Abdullah, Bergmann, Karl-Christian, Bindslev-Jensen, Carsten, Bjermer, Leif, Bonini, Matteo, Bosnic-Anticevich, Sinthia, Bosse, Isabelle, Brough, Helen A., Brussino, Luisa, Calderon, Moises A., Caraballo, Luis, Cardona, Victoria, Carreiro-Martins, Pedro, Casale, Thomas, Cecchi, Lorenzo, Cepeda Sarabia, Alfonso M., Chkhartishvili, Ekaterine, Chu, Derek K., Cirule, Ieva, Cruz, Alvaro A., Czarlewski, Wienczyslawa, Del Giacco, Stefano, Demoly, Pascal, Devillier, Philippe, Dokic, Dejan, Durham, Stephen L., Ebisawa, Motohiro, El-Gamal✝, Yehia, Emuzyte, Regina, Gamkrelidze, Amiran, Fauquert, Jean Luc, Fiocchi, Alessandro, Fokkens, Wytske J., Fonseca, Joao A., Fontaine, Jean-François, Gawlik, Radoslaw, Gelincik, Asli, Gemicioglu, Bilun, Gereda, Jose E., Gerth van Wijk, Roy, Gomez, R. Maximiliano, Gotua, Maia, Grisle, Ineta, Guzmán, Maria-Antonieta, Haahtela, Tari, Halken, Susanne, Heffler, Enrico, Hoffmann-Sommergruber, Karin, Hossny, Elham, Hrubiško, Martin, Irani, Carla, Ivancevich, Juan Carlos, Ispayeva, Zhanat, Julge, Kaja, Kaidashev, Igor, Kalayci, Omer, Khaitov, Musa, Klimek, Ludger, Knol, Edward, Kowalski, Marek L., Kraxner, Helga, Kull, Inger, Kuna, Piotr, Kvedariene, Violeta, Kritikos, Vicky, Lauerma, Antti, Lau, Susanne, Laune, Daniel, Levin, Michael, Larenas-Linnemann, Desiree E., Lodrup Carlsen, Karin C., Lombardi, Carlo, Lourenço, Olga M., Mahboub, Bassam, Malling, Hans-Jørgen, Manning, Patrick, Marshall, Gailen D., Melén, Erik, Meltzer, Eli O., Miculinic, Neven, Milenkovic, Branislava, Moin, Mostafa, Montefort, Stephen, Morais-Almeida, Mario, Mortz, Charlotte G., Mösges, Ralph, Mullol, Joaquim, Namazova Baranova, Leyla, Neffen, Hugo, Nekam, Kristof, Niedoszytko, Marek, Odemyr, Mikaëla, O'Hehir, Robyn E., Ollert, Markus, O'Mahony, Liam, Ohta, Ken, Okamoto, Yoshitaka, Okubo, Kimi, Pajno, Giovanni B., Palomares, Oscar, Palkonen, Susanna, Panzner, Petr, G. Papadopoulos, Nikolaos, Park, Hae-Sim, Passalacqua, Giovanni, Patella, Vincenzo, Pawankar, Ruby, Pham-Thi, Nhân, Plavec, Davor, Popov, Todor A., Recto, Marysia, Regateiro, Frederico S., Riggioni, Carmen, Roberts, Graham, Rodriguez-Gonzales, Monica, Rosario, Nelson, Rottem, Menachem, Rouadi, Philip W., Ryan, Dermot, Samolinski, Boleslaw, Sanchez-Borges✝, Mario, Serpa, Faradiba S., Sastre, Joaquin, Scadding, Glenis K., Shamji, Mohamed H., Schmid-Grendelmeier, Peter, Schünemann, Holger J., Sheikh, Aziz, Scichilone, Nicola, Sisul, Juan Carlos, Sofiev, Mikhail, Solé, Dirceu, Sooronbaev, Talant, Soto-Martinez, Manuel, Soto-Quiros, Manuel, Sova, Milan, Schwarze, Jürgen, Skypala, Isabel, Suppli-Ulrik, Charlotte, Taborda-Barata, Luis, Todo-Bom, Ana, Torres, Maria J., Valentin-Rostan, Marylin, Tomazic, Peter-Valentin, Valero, Antonio, Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Untersmayr, Eva, Urrutia-Pereira, Marilyn, Valiulis, Arunas, Valovirta, Erkka, Vandenplas, Olivier, Ventura, Maria Teresa, Vichyanond, Pakit, Wagenmann, Martin, Wallace, Dana, Walusiak-Skorupa, Jolanta, Wang, De Yun, Waserman, Susan, Wong, Gary W. K., Yorgancioglu, Arzu, Yusuf, Osman M., Zernotti, Mario, Zhang, Luo, Zidarn, Mihaela, Zuberbier, Torsten, Jutel, Marek, and Universitat Autònoma de Barcelona
Subjects: Precision medicine, Immunotherapy, Allergic rhinitis, Asthma
Published: 2021

9. ARIA‐EAACI care pathways for allergen immunotherapy in respiratory allergy

Author: Bousquet, Jean, primary, Pfaar, Oliver, additional, Agache, Ioana, additional, Bedbrook, Anna, additional, Akdis, Cezmi A, additional, Canonica, G. Walter, additional, Chivato, Tomas, additional, Al‐Ahmad, Mona, additional, Abdul Latiff, Amir H, additional, Ansotegui, Ignacio J, additional, Bachert, Claus, additional, Baharuddin, Abdullah, additional, Bergmann, Karl‐Christian, additional, Bindslev‐Jensen, Carsten, additional, Bjermer, Leif, additional, Bonini, Matteo, additional, Bosnic‐Anticevich, Sinthia, additional, Bosse, Isabelle, additional, Brough, Helen A., additional, Brussino, Luisa, additional, Calderon, Moises A, additional, Caraballo, Luis, additional, Cardona, Victoria, additional, Carreiro‐Martins, Pedro, additional, Casale, Tomas, additional, Cecchi, Lorenzo, additional, Cepeda Sarabia, Alfonso M, additional, Chkhartishvili, Ekaterine, additional, Chu, Derek K, additional, Cirule, Ieva, additional, Cruz, Alvaro A, additional, Czarlewski, Wienczyslawa, additional, del Giacco, Stefano, additional, Demoly, Pascal, additional, Devillier, Philippe, additional, Dokic, Dejan, additional, Durham, Stephen L, additional, Ebisawa, Motohiro, additional, El‐Gamal✝, Yehia, additional, Emuzyte, Regina, additional, Gamkrelidze, Amiran, additional, Fauquert, Jean Luc, additional, Fiocchi, Alessandro, additional, Fokkens, Wytske J, additional, Fonseca, Joao A, additional, Fontaine, Jean‐François, additional, Gawlik, Radoslaw, additional, Gelincik, Asli, additional, Gemicioglu, Bilun, additional, Gereda, Jose E, additional, Gerth van Wijk, Roy, additional, Gomez, R Maximiliano, additional, Gotua, Maia, additional, Grisle, Ineta, additional, Guzmán, Maria‐Antonieta, additional, Haahtela, Tari, additional, Halken, Susanne, additional, Heffler, Enrico, additional, Hoffmann‐Sommergruber, Karin, additional, Hossny, Elham, additional, Hrubiško, Martin, additional, Irani, Carla, additional, Ivancevich, Juan Carlos, additional, Ispayeva, Zhanat, additional, Julge, Kaja, additional, Kaidashev, Igor, additional, Kalayci, Omer, additional, Khaitov, Musa, additional, Klimek, Ludger, additional, Knol, Edward, additional, Kowalski, Marek L, additional, Kraxner, Helga, additional, Kull, Inger, additional, Kuna, Piotr, additional, Kvedariene, Violeta, additional, Kritikos, Vicky, additional, Lauerma, Antti, additional, Lau, Susanne, additional, Laune, Daniel, additional, Levin, Michael, additional, Larenas‐Linnemann, Desiree E, additional, Lodrup Carlsen, Karin C, additional, Lombardi, Carlo, additional, Lourenço, Olga M, additional, Mahboub, Bassam, additional, Malling, Hans‐Jørgen, additional, Manning, Patrick, additional, Marshall, Gailen D, additional, Melén, Erik, additional, Meltzer, Eli O, additional, Miculinic, Neven, additional, Milenkovic, Branislava, additional, Moin, Mostafa, additional, Montefort, Stephen, additional, Morais‐Almeida, Mario, additional, Mortz, Charlotte G, additional, Mösges, Ralph, additional, Mullol, Joaquim, additional, Namazova Baranova, Leyla, additional, Neffen, Hugo, additional, Nekam, Kristof, additional, Niedoszytko, Marek, additional, Odemyr, Mikaëla, additional, O'Hehir, Robyn E, additional, Ollert, Markus, additional, O'Mahony, Liam, additional, Ohta, Ken, additional, Okamoto, Yoshitaka, additional, Okubo, Kimi, additional, Pajno, Giovanni B, additional, Palomares, Oscar, additional, Palkonen, Susanna, additional, Panzner, Petr, additional, G Papadopoulos, Nikolaos, additional, Park, Hae‐Sim, additional, Passalacqua, Giovanni, additional, Patella, Vincenzo, additional, Pawankar, Ruby, additional, Pham‐Thi, Nhân, additional, Plavec, Davor, additional, Popov, Todor A, additional, Recto, Marysia, additional, Regateiro, Frederico S, additional, Riggioni, Carmen, additional, Roberts, Graham, additional, Rodriguez‐Gonzales, Monica, additional, Rosario, Nelson, additional, Rottem, Menachem, additional, Rouadi, Philip W, additional, Ryan, Dermot, additional, Samolinski, Boleslaw, additional, Sanchez‐Borges✝, Mario, additional, Serpa, Faradiba S, additional, Sastre, Joaquin, additional, Scadding, Glenis K., additional, Shamji, Mohamed H, additional, Schmid‐Grendelmeier, Peter, additional, Schünemann, Holger J, additional, Sheikh, Aziz, additional, Scichilone, Nicola, additional, Sisul, Juan Carlos, additional, Sofiev, Mikhail, additional, Solé, Dirceu, additional, Sooronbaev, Talant, additional, Soto‐Martinez, Manuel, additional, Soto‐Quiros, Manuel, additional, Sova, Milan, additional, Schwarze, Jürgen, additional, Skypala, Isabel, additional, Suppli‐Ulrik, Charlotte, additional, Taborda‐Barata, Luis, additional, Todo‐Bom, Ana, additional, Torres, Maria J, additional, Valentin‐Rostan, Marylin, additional, Tomazic, Peter‐Valentin, additional, Valero, Antonio, additional, Toppila‐Salmi, Sanna, additional, Tsiligianni, Ioanna, additional, Untersmayr, Eva, additional, Urrutia‐Pereira, Marilyn, additional, Valiulis, Arunas, additional, Valovirta, Erkka, additional, Vandenplas, Olivier, additional, Ventura, Maria Teresa, additional, Vichyanond, Pakit, additional, Wagenmann, Martin, additional, Wallace, Dana, additional, Walusiak‐Skorupa, Jolanta, additional, Wang, De Yun, additional, Waserman, Susan, additional, Wong, Gary WK, additional, Yorgancioglu, Arzu, additional, Yusuf, Osman M, additional, Zernotti, Mario, additional, Zhang, Luo, additional, Zidarn, Mihaela, additional, Zuberbier, Torsten, additional, and Jutel, Marek, additional
Published: 2021
Full Text: View/download PDF

10. ARIA-EAACI statement on asthma and COVID-19 (June 2, 2020)

Author: Bousquet, Jean, Jutel, Marek, Akdis, Cezmi A., Klimek, Ludger, Pfaar, Oliver, Nadeau, Kari C., Eiwegger, Thomas, Bedbrook, Anna, Ansotegui, Ignacio J., Anto, Josep M., Bachert, Claus, Bateman, Eric D., Bennoor, Kazi S., Berghea, Elena Camelia, Bergmann, Karl Christian, Blain, Hubert, Bonini, Mateo, Bosnic-Anticevich, Sinthia, Boulet, Louis Philippe, Brussino, Luisa, Buhl, Roland, Camargos, Paulo, Canonica, Giorgio Walter, Cardona, Victoria, Casale, Thomas, Chinthrajah, Sharon, Akdis, Mübeccel, Chivato, Tomas, Christoff, George, Cruz, Alvaro A., Czarlewski, Wienczyslawa, Del Giacco, Stefano, Du, Hui, El-Gamal, Yehia, Fokkens, Wytske J., Fonseca, Joao A., Gao, Yadong, Gaga, Mina, Gemicioglu, Bilun, Gotua, Maia, Haahtela, Tari, Halpin, David, Hamelmann, Eckard, Hoffmann-Sommergruber, Karin, Humbert, Marc, Ilina, Nataliya, Ivancevich, Juan Carlos, Joos, Guy, Khaitov, Musa, Kirenga, Bruce, Knol, Edward F., Ko, Fanny W., Koskinen, Seppo, Kowalski, Marek L., Kraxner, Helga, Kudlay, Dmitry, Kuna, Piotr, Kupczyk, Maciej, Kvedariene, Violeta, Abdul Latiff, Amir H., Le, Lan T., Levin, Michael, Larenas-Linnemann, Desiree, Louis, Renaud, Masjedi, Mohammad R., Melén, Erik, Mihaltan, Florin, Milenkovic, Branislava, Mohammad, Yousser, Morais-Almeida, Mario, Mullol, Joaquim, Namazova, Leyla, Neffen, Hugo, Nunes, Elisabete, O’Byrne, Paul, O’Hehir, Robyn, O’Mahony, Liam, Ohta, Ken, Okamoto, Yoshitaka, Onorato, Gabrielle L., Panzner, Petr, Papadopoulos, Nikos G., Passalacqua, Gianni, Patella, Vincenzo, Pawankar, Ruby, Pham-Thi, Nhân, Pigearias, Bernard, Popov, Todor A., Puggioni, Francesca, Regateiro, Frederico S., Rolla, Giovanni, Rottem, Menachem, Samolinski, Boleslaw, Sastre, Joaquin, Schwarze, Jurgen, Sheikh, Aziz, Scichilone, Nicola, Soto-Quiros, Manuel, Soto-Martinez, Manuel, Sova, Milan, Nicola, Stefania, Stelmach, Rafael, Suppli-Ulrik, Charlotte, Taborda-Barata, Luis, To, Teresa, Tomazic, Peter Valentin, Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Usmani, Omar, Valiulis, Arunas, Ventura, Maria Teresa, Viegi, Giovanni, Vontetsianos, Theodor, Wang, De Yun, Williams, Sian, Wong, Gary W.K., Yorgancioglu, Arzu, Zernotti, Mario, Zidarn, Mihaela, Zuberbier, Torsten, Agache, Ioana, Bousquet, Jean, Jutel, Marek, Akdis, Cezmi A., Klimek, Ludger, Pfaar, Oliver, Nadeau, Kari C., Eiwegger, Thomas, Bedbrook, Anna, Ansotegui, Ignacio J., Anto, Josep M., Bachert, Claus, Bateman, Eric D., Bennoor, Kazi S., Berghea, Elena Camelia, Bergmann, Karl Christian, Blain, Hubert, Bonini, Mateo, Bosnic-Anticevich, Sinthia, Boulet, Louis Philippe, Brussino, Luisa, Buhl, Roland, Camargos, Paulo, Canonica, Giorgio Walter, Cardona, Victoria, Casale, Thomas, Chinthrajah, Sharon, Akdis, Mübeccel, Chivato, Tomas, Christoff, George, Cruz, Alvaro A., Czarlewski, Wienczyslawa, Del Giacco, Stefano, Du, Hui, El-Gamal, Yehia, Fokkens, Wytske J., Fonseca, Joao A., Gao, Yadong, Gaga, Mina, Gemicioglu, Bilun, Gotua, Maia, Haahtela, Tari, Halpin, David, Hamelmann, Eckard, Hoffmann-Sommergruber, Karin, Humbert, Marc, Ilina, Nataliya, Ivancevich, Juan Carlos, Joos, Guy, Khaitov, Musa, Kirenga, Bruce, Knol, Edward F., Ko, Fanny W., Koskinen, Seppo, Kowalski, Marek L., Kraxner, Helga, Kudlay, Dmitry, Kuna, Piotr, Kupczyk, Maciej, Kvedariene, Violeta, Abdul Latiff, Amir H., Le, Lan T., Levin, Michael, Larenas-Linnemann, Desiree, Louis, Renaud, Masjedi, Mohammad R., Melén, Erik, Mihaltan, Florin, Milenkovic, Branislava, Mohammad, Yousser, Morais-Almeida, Mario, Mullol, Joaquim, Namazova, Leyla, Neffen, Hugo, Nunes, Elisabete, O’Byrne, Paul, O’Hehir, Robyn, O’Mahony, Liam, Ohta, Ken, Okamoto, Yoshitaka, Onorato, Gabrielle L., Panzner, Petr, Papadopoulos, Nikos G., Passalacqua, Gianni, Patella, Vincenzo, Pawankar, Ruby, Pham-Thi, Nhân, Pigearias, Bernard, Popov, Todor A., Puggioni, Francesca, Regateiro, Frederico S., Rolla, Giovanni, Rottem, Menachem, Samolinski, Boleslaw, Sastre, Joaquin, Schwarze, Jurgen, Sheikh, Aziz, Scichilone, Nicola, Soto-Quiros, Manuel, Soto-Martinez, Manuel, Sova, Milan, Nicola, Stefania, Stelmach, Rafael, Suppli-Ulrik, Charlotte, Taborda-Barata, Luis, To, Teresa, Tomazic, Peter Valentin, Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Usmani, Omar, Valiulis, Arunas, Ventura, Maria Teresa, Viegi, Giovanni, Vontetsianos, Theodor, Wang, De Yun, Williams, Sian, Wong, Gary W.K., Yorgancioglu, Arzu, Zernotti, Mario, Zidarn, Mihaela, Zuberbier, Torsten, and Agache, Ioana
Published: 2021

11. ARIA-EAACI statement on Asthma and COVID-19 (June 2, 2020)

Author: CTI Research, CTI, MS Dermatologie/Allergologie, Infection & Immunity, Bousquet, Jean, Jutel, Marek, Akdis, Cezmi A, Klimek, Ludger, Pfaar, Oliver, Nadeau, Kari C, Eiwegger, Thomas, Bedbrook, Anna, Ansotegui, Ignacio J, Anto, Josep M, Bachert, Claus, Bateman, Eric D, Bennoor, Kazi S, Berghea, Emilia Camelia, Bergmann, Karl-Christian, Blain, Hubert, Bonini, Mateo, Bosnic-Anticevich, Sinthia, Boulet, Louis-Philippe, Brussino, Luisa, Buhl, Roland, Camargos, Paulo, Canonica, G Walter, Cardona, Victoria, Casale, Thomas, Chinthrajah, Sharon, Akdis, Mübeccel, Chivato, Tomas, Christoff, George, Cruz, Alvaro A, Czarlewski, Wienczyslawa, Del Giacco, Stefano, Du, Hui, El-Gamal, Yehia, Fokkens, Wytske J, Fonseca, Joao A, Gao, Yadong, Gaga, Mina, Gemicioglu, Bilun, Gotua, Maia, Haahtela, Tari, Halpin, David, Hamelmann, Eckard, Hoffmann-Sommergruber, Karin, Humbert, Marc, Ilina, Nataliya, Ivancevich, Juan-Carlos, Joos, Guy, Khaitov, Musa, Kirenga, Bruce, Knol, Edward F, Ko, Fanny W, Koskinen, Seppo, Kowalski, Marek L, Kraxner, Helga, Kudlay, Dmitri, Kuna, Piotr, Kupczyk, Maciej, Kvedariene, Violeta, Abdul Latiff, Amir H, Le, Lan T, Levin, Michael, Larenas-Linnemann, Desiree, Louis, Renaud, Masjedi, Mohammad R, Melén, Erik, Mihaltan, Florin, Milenkovic, Branislava, Mohammad, Yousser, Morais-Almeida, Mario, Mullol, Joaquim, Namazova, Leyla, Neffen, Hugo, Nunes, Elisabete, O'Byrne, Paul, O'Hehir, Robyn, O'Mahony, Liam, Ohta, Ken, Okamoto, Yoshitaka, Onorato, Gabrielle L, Panzner, Petr, Papadopoulos, Nikos G, Passalacqua, Gianni, Patella, Vincenzo, Pawankar, Ruby, Pham-Thi, Nhân, Pigearias, Bernard, Popov, Todor A, Puggioni, Francesca, Regateiro, Frederico S, Rolla, Giovanni, Rottem, Menachem, Samolinski, Boleslaw, Sastre, Joaquin, Schwarze, Jurgen, Sheikh, Aziz, Scichilone, Nicola, Soto-Quiros, Manuel, Sova, Milan, Nicola, Stefania, Stelmach, Rafael, Suppli-Ulrik, Charlotte, Taborda-Barata, Luis, To, Teresa, Tomazic, Peter-Valentin, Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Usmani, Omar, Valiulis, Arunas, Ventura, Maria Teresa, Viegi, Giovanni, Vontetsianos, Theodor, Wang, De Yun, Williams, Sian, Wong, Gary Wk, Yorgancioglu, Arzu, Zernotti, Mario, Zidarn, Mihaela, Zuberbier, Torsten, Agache, Ioana, CTI Research, CTI, MS Dermatologie/Allergologie, Infection & Immunity, Bousquet, Jean, Jutel, Marek, Akdis, Cezmi A, Klimek, Ludger, Pfaar, Oliver, Nadeau, Kari C, Eiwegger, Thomas, Bedbrook, Anna, Ansotegui, Ignacio J, Anto, Josep M, Bachert, Claus, Bateman, Eric D, Bennoor, Kazi S, Berghea, Emilia Camelia, Bergmann, Karl-Christian, Blain, Hubert, Bonini, Mateo, Bosnic-Anticevich, Sinthia, Boulet, Louis-Philippe, Brussino, Luisa, Buhl, Roland, Camargos, Paulo, Canonica, G Walter, Cardona, Victoria, Casale, Thomas, Chinthrajah, Sharon, Akdis, Mübeccel, Chivato, Tomas, Christoff, George, Cruz, Alvaro A, Czarlewski, Wienczyslawa, Del Giacco, Stefano, Du, Hui, El-Gamal, Yehia, Fokkens, Wytske J, Fonseca, Joao A, Gao, Yadong, Gaga, Mina, Gemicioglu, Bilun, Gotua, Maia, Haahtela, Tari, Halpin, David, Hamelmann, Eckard, Hoffmann-Sommergruber, Karin, Humbert, Marc, Ilina, Nataliya, Ivancevich, Juan-Carlos, Joos, Guy, Khaitov, Musa, Kirenga, Bruce, Knol, Edward F, Ko, Fanny W, Koskinen, Seppo, Kowalski, Marek L, Kraxner, Helga, Kudlay, Dmitri, Kuna, Piotr, Kupczyk, Maciej, Kvedariene, Violeta, Abdul Latiff, Amir H, Le, Lan T, Levin, Michael, Larenas-Linnemann, Desiree, Louis, Renaud, Masjedi, Mohammad R, Melén, Erik, Mihaltan, Florin, Milenkovic, Branislava, Mohammad, Yousser, Morais-Almeida, Mario, Mullol, Joaquim, Namazova, Leyla, Neffen, Hugo, Nunes, Elisabete, O'Byrne, Paul, O'Hehir, Robyn, O'Mahony, Liam, Ohta, Ken, Okamoto, Yoshitaka, Onorato, Gabrielle L, Panzner, Petr, Papadopoulos, Nikos G, Passalacqua, Gianni, Patella, Vincenzo, Pawankar, Ruby, Pham-Thi, Nhân, Pigearias, Bernard, Popov, Todor A, Puggioni, Francesca, Regateiro, Frederico S, Rolla, Giovanni, Rottem, Menachem, Samolinski, Boleslaw, Sastre, Joaquin, Schwarze, Jurgen, Sheikh, Aziz, Scichilone, Nicola, Soto-Quiros, Manuel, Sova, Milan, Nicola, Stefania, Stelmach, Rafael, Suppli-Ulrik, Charlotte, Taborda-Barata, Luis, To, Teresa, Tomazic, Peter-Valentin, Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Usmani, Omar, Valiulis, Arunas, Ventura, Maria Teresa, Viegi, Giovanni, Vontetsianos, Theodor, Wang, De Yun, Williams, Sian, Wong, Gary Wk, Yorgancioglu, Arzu, Zernotti, Mario, Zidarn, Mihaela, Zuberbier, Torsten, and Agache, Ioana
Published: 2021

12. The EAACI/GA²LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria

Author: Zuberbier, T., primary, Aberer, Werner, primary, Asero, R., primary, Abdul Latiff, A. H., primary, Baker, D., primary, Ballmer-Weber, B., primary, Bernstein, J. A., primary, Bindslev-Jensen, C., primary, Brzoza, Z., primary, Buense Bedrikow, R., primary, Canonica, G. W., primary, Church, M. K., primary, Craig, T., primary, Danilycheva, I. V., primary, Dressler, C., primary, Ensina, L. F., primary, Gimenez-Arnau, A., primary, Godse, K., primary, Goncalo, M., primary, Grattan, C., primary, and Hebert, J., primary
Published: 2021
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13. ARIA‐EAACI statement on asthma and COVID‐19 (June 2, 2020)

Author: Bousquet, Jean, primary, Jutel, Marek, additional, Akdis, Cezmi A., additional, Klimek, Ludger, additional, Pfaar, Oliver, additional, Nadeau, Kari C., additional, Eiwegger, Thomas, additional, Bedbrook, Anna, additional, Ansotegui, Ignacio J., additional, Anto, Josep M., additional, Bachert, Claus, additional, Bateman, Eric D., additional, Bennoor, Kazi S., additional, Berghea, Elena Camelia, additional, Bergmann, Karl‐Christian, additional, Blain, Hubert, additional, Bonini, Mateo, additional, Bosnic‐Anticevich, Sinthia, additional, Boulet, Louis‐Philippe, additional, Brussino, Luisa, additional, Buhl, Roland, additional, Camargos, Paulo, additional, Canonica, Giorgio Walter, additional, Cardona, Victoria, additional, Casale, Thomas, additional, Chinthrajah, Sharon, additional, Akdis, Mübeccel, additional, Chivato, Tomas, additional, Christoff, George, additional, Cruz, Alvaro A., additional, Czarlewski, Wienczyslawa, additional, Del Giacco, Stefano, additional, Du, Hui, additional, El‐Gamal, Yehia, additional, Fokkens, Wytske J., additional, Fonseca, Joao A., additional, Gao, Yadong, additional, Gaga, Mina, additional, Gemicioglu, Bilun, additional, Gotua, Maia, additional, Haahtela, Tari, additional, Halpin, David, additional, Hamelmann, Eckard, additional, Hoffmann‐Sommergruber, Karin, additional, Humbert, Marc, additional, Ilina, Nataliya, additional, Ivancevich, Juan‐Carlos, additional, Joos, Guy, additional, Khaitov, Musa, additional, Kirenga, Bruce, additional, Knol, Edward F., additional, Ko, Fanny W., additional, Koskinen, Seppo, additional, Kowalski, Marek L., additional, Kraxner, Helga, additional, Kudlay, Dmitry, additional, Kuna, Piotr, additional, Kupczyk, Maciej, additional, Kvedariene, Violeta, additional, Abdul Latiff, Amir H., additional, Le, Lan T., additional, Levin, Michael, additional, Larenas‐Linnemann, Desiree, additional, Louis, Renaud, additional, Masjedi, Mohammad R., additional, Melén, Erik, additional, Mihaltan, Florin, additional, Milenkovic, Branislava, additional, Mohammad, Yousser, additional, Morais‐Almeida, Mario, additional, Mullol, Joaquim, additional, Namazova, Leyla, additional, Neffen, Hugo, additional, Nunes, Elisabete, additional, O’Byrne, Paul, additional, O’Hehir, Robyn, additional, O’Mahony, Liam, additional, Ohta, Ken, additional, Okamoto, Yoshitaka, additional, Onorato, Gabrielle L., additional, Panzner, Petr, additional, Papadopoulos, Nikos G., additional, Passalacqua, Gianni, additional, Patella, Vincenzo, additional, Pawankar, Ruby, additional, Pham‐Thi, Nhân, additional, Pigearias, Bernard, additional, Popov, Todor A., additional, Puggioni, Francesca, additional, Regateiro, Frederico S., additional, Rolla, Giovanni, additional, Rottem, Menachem, additional, Samolinski, Boleslaw, additional, Sastre, Joaquin, additional, Schwarze, Jurgen, additional, Sheikh, Aziz, additional, Scichilone, Nicola, additional, Soto‐Quiros, Manuel, additional, Soto‐Martinez, Manuel, additional, Sova, Milan, additional, Nicola, Stefania, additional, Stelmach, Rafael, additional, Suppli‐Ulrik, Charlotte, additional, Taborda‐Barata, Luis, additional, To, Teresa, additional, Tomazic, Peter‐Valentin, additional, Toppila‐Salmi, Sanna, additional, Tsiligianni, Ioanna, additional, Usmani, Omar, additional, Valiulis, Arunas, additional, Ventura, Maria Teresa, additional, Viegi, Giovanni, additional, Vontetsianos, Theodor, additional, Wang, De Yun, additional, Williams, Sian, additional, Wong, Gary W. K., additional, Yorgancioglu, Arzu, additional, Zernotti, Mario, additional, Zidarn, Mihaela, additional, Zuberbier, Torsten, additional, and Agache, Ioana, additional
Published: 2020
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14. Challenges and Pitfalls in the Diagnosis and Management of Non-IgE Cow’s Milk Protein Allergy: Two Cases

Author: Nicolaou, Nicolaos, primary, Abdul Latiff, Amir H., additional, Kudla, Urszula, additional, and Muhardi, Leilani, additional
Published: 2020
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15. The EAACI/GA²LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria.

Author: Zuberbier, T., Aberer, W., Asero, R., Abdul Latiff, A. H., Baker, D., Ballmer‐Weber, B., Bernstein, J. A., Bindslev‐Jensen, C., Brzoza, Z., Buense Bedrikow, R., Canonica, G. W., Church, M. K., Craig, T., Danilycheva, I. V., Dressler, C., Ensina, L. F., Giménez‐Arnau, A., Godse, K., Gonçalo, M., and Grattan, C.
Subjects: TREATMENT of urticaria, DERMATOLOGY, SKIN inflammation, INDIVIDUALIZED medicine, CLINICAL immunology
Abstract: Abstract: This evidence‐ and consensus‐based guideline was developed following the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. The conference was held on 1 December 2016. It is a joint initiative of the Dermatology Section of the European Academy of Allergology and Clinical Immunology (EAACI), the EU‐founded network of excellence, the Global Allergy and Asthma European Network (GA²LEN), the European Dermatology Forum (EDF) and the World Allergy Organization (WAO) with the participation of 48 delegates of 42 national and international societies. This guideline was acknowledged and accepted by the European Union of Medical Specialists (UEMS). Urticaria is a frequent, mast cell‐driven disease, presenting with wheals, angioedema, or both. The lifetime prevalence for acute urticaria is approximately 20%. Chronic spontaneous urticaria and other chronic forms of urticaria are disabling, impair quality of life and affect performance at work and school. This guideline covers the definition and classification of urticaria, taking into account the recent progress in identifying its causes, eliciting factors and pathomechanisms. In addition, it outlines evidence‐based diagnostic and therapeutic approaches for the different subtypes of urticaria. [ABSTRACT FROM AUTHOR]
Published: 2018
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16. PATIENT-CENTRED SCREENING FOR PRIMARY IMMUNODEFICIENCY, A MULTI-STAGE DIAGNOSTIC PROTOCOL DESIGNED FOR NONIMMUNOLOGISTS: 2011 UPDATE

Author: De Vries, E., primary, Cardona, A. A., additional, Abdul Latiff, A. H., additional, Badolato, R., additional, Brodszki, N., additional, Cant, A. J., additional, Carbone, J., additional, Casper, J. T., additional, Ciznar, A., additional, Cochino, A. V., additional, Derfalvi, B., additional, Driessen, G. J., additional, Elfeky, R., additional, El-Ghoneimy, D., additional, Espanol, T., additional, Etzioni, A., additional, Gambineri, E., additional, Gilmour, K., additional, Gonzalez-Granado, L. I., additional, Guseva, M. N., additional, Haverkamp, M. H., additional, Helminen, M., additional, Honig, M., additional, Kanariou, M. G., additional, Kirschfink, M., additional, Klein, C., additional, Kuijpers, T. W., additional, Kutukculer, N., additional, Martire, B., additional, Meyts, I., additional, Niehues, T., additional, Pignata, C., additional, Reda, S. M., additional, Renner, E. D., additional, Rezaei, N., additional, Rizzi, M., additional, Sampalo Lainz, M. A., additional, Sargur, R. B., additional, Sediva, A., additional, Seidel, M. G., additional, Seneviratne, S. L., additional, Soler-Palacin, P., additional, Tommasini, A., additional, and Warnatz, K., additional
Published: 2014
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17. Methods report on the development of the 2013 revision and update of the EAACI/GA2LEN/EDF/WAO guideline for the definition, classification, diagnosis, and management of urticaria

Author: Zuberbier, T., primary, Aberer, W., additional, Asero, R., additional, Bindslev-Jensen, C., additional, Brzoza, Z., additional, Canonica, G. W., additional, Church, M. K., additional, Ensina, L. F., additional, Giménez-Arnau, A., additional, Godse, K., additional, Gonçalo, M., additional, Grattan, C., additional, Hebert, J., additional, Hide, M., additional, Kaplan, A., additional, Kapp, A., additional, Abdul Latiff, A. H., additional, Mathelier-Fusade, P., additional, Metz, M., additional, Saini, S. S., additional, Sánchez-Borges, M., additional, Schmid-Grendelmeier, P., additional, Simons, F. E. R., additional, Staubach, P., additional, Sussman, G., additional, Toubi, E., additional, Vena, G. A., additional, Wedi, B., additional, Zhu, X. J., additional, Nast, A., additional, and Maurer, M., additional
Published: 2014
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18. The EAACI/GA2LEN/EDF/WAO Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update

Author: Zuberbier, T., primary, Aberer, W., additional, Asero, R., additional, Bindslev-Jensen, C., additional, Brzoza, Z., additional, Canonica, G. W., additional, Church, M. K., additional, Ensina, L. F., additional, Giménez-Arnau, A., additional, Godse, K., additional, Gonçalo, M., additional, Grattan, C., additional, Hebert, J., additional, Hide, M., additional, Kaplan, A., additional, Kapp, A., additional, Abdul Latiff, A. H., additional, Mathelier-Fusade, P., additional, Metz, M., additional, Nast, A., additional, Saini, S. S., additional, Sánchez-Borges, M., additional, Schmid-Grendelmeier, P., additional, Simons, F. E. R., additional, Staubach, P., additional, Sussman, G., additional, Toubi, E., additional, Vena, G. A., additional, Wedi, B., additional, Zhu, X. J., additional, and Maurer, M., additional
Published: 2014
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19. The EAACI/ GA2 LEN/ EDF/ WAO Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update.

Author: Zuberbier, T., Aberer, W., Asero, R., Bindslev-Jensen, C., Brzoza, Z., Canonica, G. W., Church, M. K., Ensina, L. F., Giménez-Arnau, A., Godse, K., Gonçalo, M., Grattan, C., Hebert, J., Hide, M., Kaplan, A., Kapp, A., Abdul Latiff, A. H., Mathelier-Fusade, P., Metz, M., and Nast, A.
Subjects: TREATMENT of urticaria, URTICARIA, NOSOLOGY, SYSTEMATIC reviews, QUALITY of life, DIAGNOSIS
Abstract: This guideline is the result of a systematic literature review using the ' Grading of Recommendations Assessment, Development and Evaluation' ( GRADE) methodology and a structured consensus conference held on 28 and 29 November 2012, in Berlin. It is a joint initiative of the Dermatology Section of the European Academy of Allergy and Clinical Immunology ( EAACI), the EU-funded network of excellence, the Global Allergy and Asthma European Network ( GA2 LEN), the European Dermatology Forum ( EDF), and the World Allergy Organization ( WAO) with the participation of delegates of 21 national and international societies. Urticaria is a frequent, mast cell-driven disease, presenting with wheals, angioedema, or both. The life-time prevalence for acute urticaria is approximately 20%. Chronic spontaneous urticaria and other chronic forms of urticaria do not only cause a decrease in quality of life, but also affect performance at work and school and, as such, are members of the group of severe allergic diseases. This guideline covers the definition and classification of urticaria, taking into account the recent progress in identifying its causes, eliciting factors and pathomechanisms. In addition, it outlines evidence-based diagnostic and therapeutic approaches for the different subtypes of urticaria. This guideline was acknowledged and accepted by the European Union of Medical Specialists ( UEMS). [ABSTRACT FROM AUTHOR]
Published: 2014
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20. The clinical significance of immunoglobulin A deficiency.

Author: Abdul Latiff, Amir H. and Kerr, Michael A.
Subjects: *IMMUNOGLOBULIN A, *IMMUNODEFICIENCY, *GASTROINTESTINAL diseases, *CELIAC disease, *AUTOIMMUNE diseases, *VIRUS diseases
Abstract: IgA deficiency is the most common primary immunoglobulin deficiency. The prevalence in Caucasians is around one in 500, whereas in some Asian populations it is very uncommon. Most individuals with IgA deficiency are clinically asymptomatic. Those with symptoms of immunodeficiency have predominantly sinopulmonary or gastrointestinal infections, which are more severe when associated with IgG2, IgG4 or specific antibody deficiency. IgA deficiency is believed to be one end of a spectrum of immunodeficiency with common variable immunodeficiency at the most severe end. Although primary IgA deficiency is the most commonly encountered form, secondary deficiencies due to drugs or viral infections are recognized. IgA deficiencies can be partial or transient Primary IgA deficiency is caused by a defect of terminal lymphocyte differentiation, which leads to underproduction of serum and mucosal IgA; affected individuals have normal IgA genes. A number of non-immunoglobulin genes have been implicated in IgA deficiency. There have been many diseases reported in association with IgA deficiency, particularly autoimmune diseases. The most common association is with coeliac disease (CD), which has special significance since CD is usually diagnosed by detection of specific IgA antibodies that are obviously lacking in IgA deficiency. There is no specific treatment for patients with symptomatic IgA deficiency. Antibiotics are prescribed in those with acute infections. A significant proportion of IgA-deficient individuals are reported to have anti-IgA antibodies in their serum. Although blood or blood products given to IgA-deficient individuals can lead to severe, even fatal, transfusion reactions, such reactions are rare. [ABSTRACT FROM AUTHOR]
Published: 2007
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21. Patient-centred screening for primary immunodeficiency, a multi-stage diagnostic protocol designed for non-immunologists: 2011 update

Author: Array Эльфеки, Array Гилмор, Array Хельминен, Array В. Кочино, Array Чижняр, Array Эспаньол, Array Х. Абдул-Латиф, Array Седива, Array Б. Саргур, Array Нихюэс, Array Пиньята, Array Варнатц, Array Рицци, Array Гамбинери, Array Альварес Кардона, Array Н. Гусева, Array Киршфинк, Array Д. Реннер, Array де Вриз, М Х Array, Array B. Кёйперс, Array И. Гонсалес-Гранадо, Array Г. Канариу, Array Хёниг, Array Карбоне, Array Й. Дриссен, Array Резаеи, Array Г. Зайдель, Array Мейтс, Array Томмазини, Array Ациони, Array Т. Каспер, Array Кляйн, Array Дерфальви, Array Дж. Кант, Array Солер-Паласин, Array Мартире, Array А. Сампало Лайнс, Array М. Рида, Array Бадолато, Array Кутукджюлер, Array Л. Сеневиратне, Array Бродшки, Array Эль-Гонейми, AII - Amsterdam institute for Infection and Immunity, Paediatric Infectious Diseases / Rheumatology / Immunology, de Vries, E., Alvarez Cardona, A., Abdul Latiff, A. H., Badolato, R., Brodszki, N., Cant, A. J., Carbone, J., Casper, J. T., Čižnár, P., Cochino, A. V., Derfalvi, B., Driessen, G. J., Elfeky, R., El Ghoneimy, D., Espanol, T, Etzioni, A, Gambineri, E, Gilmour, K, Gonzalez Granado, Li, Haverkamp, Mh, Helminen, M, Hönig, H, Kanariou, Mg, Kirschfink, M, Klein, C., Kuijpers, T. W., Kutukculer, N., Martire, B., Meyts, I., Niehues, T., Pignata, Claudio, Reda, S. M., Renner, E. D., Rezaei, N., Rizzi, M., Sampalo Lainz, M. A., Sargur, R. B., Sediva, A., Seidel, M. G., Seneviratne, S. L., Soler Palacín, P., Tommasini, A., Warnatz, K., de Vries, E, and Tommasini, A
Subjects: Adult, immunological evaluation, medicine.medical_specialty, Translational Studies, update, General Practice, Immunology, Infections, primary immunodeficiency, Pediatrics, Diagnostic protocol, Immunological evaluation, Primary immunodeficiency, Update, Immunophenotyping, Clinical Protocols, Recurrence, Patient-Centered Care, medicine, Humans, Mass Screening, Immunology and Allergy, Medical physics, Age of Onset, Child, Medical History Taking, Physical Examination, Immunodeficiency, Protocol (science), diagnostic protocol, business.industry, Incidence, Immunologic Deficiency Syndromes, RC581-607, Cytotoxicity Tests, Immunologic, medicine.disease, Lymphocyte Subsets, Multi stage, Early Diagnosis, Phenotype, PID, diagnostic protocols, Medical emergency, Immunologic diseases. Allergy, business, Patient centred, Granulocytes
Abstract: Summary Members of the European Society for Immunodeficiencies (ESID) and other colleagues have updated the multi-stage expert-opinion-based diagnostic protocol for non-immunologists incorporating newly defined primary immunodeficiency diseases (PIDs). The protocol presented here aims to increase the awareness of PIDs among doctors working in different fields. Prompt identification of PID is important for prognosis, but this may not be an easy task. The protocol therefore starts from the clinical presentation of the patient. Because PIDs may present at all ages, this protocol is aimed at both adult and paediatric physicians. The multi-stage design allows cost-effective screening for PID of the large number of potential cases in the early phases, with more expensive tests reserved for definitive classification in collaboration with a specialist in the field of immunodeficiency at a later stage.
Published: 2012

22. Clinical and laboratory observation on immunoglobulin replacement therapy switching from an intravenous to a subcutaneous route in a Malaysian X-linked agammaglobulinemia patient.

Author: Adli A, Wahab AA, Abdul Latiff AH, Ismail IH, Faizah MZ, Boekhren KB, and Noh LM
Subjects: Humans, Immunoglobulin G therapeutic use, Infusions, Subcutaneous, Male, Agammaglobulinemia diagnosis, Agammaglobulinemia drug therapy, Genetic Diseases, X-Linked diagnosis, Genetic Diseases, X-Linked drug therapy
Abstract: We report a clinical and laboratory observation in a boy with X-linked agammaglobulinemia (XLA) who underwent an immunoglobulin replacement therapy (IRT) via the subcutaneous route (IGSC) seven years after his IRT via intravenous route (IGIV). He was free of invasive infections when on IGIV but not the troublesome coughs a week before the next infusion. A switch to a subcutaneous route resulted in significant improvement of symptoms with good weight gain. When on 2-weekly IGSC cycle, adjusting dose for weight resulted in an IgG trough level of > 600 mg/dl.
Published: 2022

23. Clinical-Epidemiological Pattern of Primary Immunodeficiencies in Malaysia 1987-2006: A 20 year experience in Four Malaysian Hospitals.

Author: Noh LM, Nasuruddin BA, Abdul Latiff AH, Noah RM, Kamarul Azahar MR, Norzila MZ, Zulkifli I, Gill HK, Nik Zainal NI, Suhaimi AW, Nik Khairulddin NY, Maraina H, Intan HI, Mat I, Shahnaz M, and B H O A
Subjects: Humans, Immunologic Deficiency Syndromes, Malaysia, Surveys and Questionnaires, Delayed Diagnosis, Registries
Abstract: Aim of Study: To determine the clinical and epidemiological characteristics of patients seen with primary immunodeficiencies referred at four Malaysian Hospitals between 1987 to 2007., Methods: Patient data were retrospectively obtained from patient records and supplemented by information from a standardized questionnaires taken at the time of diagnosis from 4 participating hospitals. The completed data were transferred to document records kept by the first author. The diagnoses made were based on criteria set by WHO Scientific Committee 1986., Results: Fifty one (51) patients with completed records satisfied the criteria of primary immunodeficiencies based on WHO Scientific Committee 1986. Predominant Antibody deficiency (40.4%) is the commonest of the class of primary immunodeficiency (based on modified IUIS classification) followed by phagocytic defect (17.3%), combined immunodeficiencies (15.4%) and other cellular immunodeficiencies (11.5%). The commonest clinical presentation is pneumonia (54%) . A positive Family history with a close family relative afflicted was a strong pointer to diagnosis for PID (52.6%) Primary immnodeficiencies are seen in all the major ethnic groups of Malaysia, predominantly among Malays. As observed in other patient registries, diagnostic delay remains the major cause of morbidity and mortality., Conclusion: Primary immunodeficiencies is relative rare but is an emerging disease in Malaysia. Creating awareness of the disease, may reveal more cases within the community. It is sufficient to be a health issue in Malaysia as in other developing countries in the future.
Published: 2013

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23 results on '"Abdul Latiff, A H"'

1. A Hybrid Approach for Subsurface Illumination Analysis in Shallow Gas Region: A Case Study in Malay Basin

2. Rhinitis associated with asthma is distinct from rhinitis alone:The ARIA-MeDALL hypothesis

3. Rhinitis associated with asthma is distinct from rhinitis alone: The ARIA-MeDALL hypothesis

4. Rhinitis associated with asthma is distinct from rhinitis alone: The ARIA‐MeDALL hypothesis

5. The ARIA-MeDALL hypothesis

6. Multiscale Carbonate Stratigraphic and Reservoir Calibration for Mk Field in Central Luconia Province

7. Is diet partly responsible for differences in COVID-19 death rates between and within countries?

8. ARIA-EAACI care pathways for allergen immunotherapy in respiratory allergy

9. ARIA‐EAACI care pathways for allergen immunotherapy in respiratory allergy

10. ARIA-EAACI statement on asthma and COVID-19 (June 2, 2020)

11. ARIA-EAACI statement on Asthma and COVID-19 (June 2, 2020)

12. The EAACI/GA²LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria

13. ARIA‐EAACI statement on asthma and COVID‐19 (June 2, 2020)

14. Challenges and Pitfalls in the Diagnosis and Management of Non-IgE Cow’s Milk Protein Allergy: Two Cases

15. The EAACI/GA²LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria.

16. PATIENT-CENTRED SCREENING FOR PRIMARY IMMUNODEFICIENCY, A MULTI-STAGE DIAGNOSTIC PROTOCOL DESIGNED FOR NONIMMUNOLOGISTS: 2011 UPDATE

17. Methods report on the development of the 2013 revision and update of the EAACI/GA2LEN/EDF/WAO guideline for the definition, classification, diagnosis, and management of urticaria

18. The EAACI/GA2LEN/EDF/WAO Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update

19. The EAACI/ GA2 LEN/ EDF/ WAO Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update.

20. The clinical significance of immunoglobulin A deficiency.

21. Patient-centred screening for primary immunodeficiency, a multi-stage diagnostic protocol designed for non-immunologists: 2011 update

22. Clinical and laboratory observation on immunoglobulin replacement therapy switching from an intravenous to a subcutaneous route in a Malaysian X-linked agammaglobulinemia patient.

23. Clinical-Epidemiological Pattern of Primary Immunodeficiencies in Malaysia 1987-2006: A 20 year experience in Four Malaysian Hospitals.

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23 results on '"Abdul Latiff, A H"'

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