43 results on '"Aas V"'
Search Results
2. Chronic hyperglycaemia promotes lipogenesis and triacylglycerol accumulation in human skeletal muscle cells
- Author
-
Aas, V., Kase, E. T., Solberg, R., Jensen, J., and Rustan, A. C.
- Published
- 2004
- Full Text
- View/download PDF
3. C-Reactive Protein Triggers Calcium Signalling in Human Neutrophilic Granulocytes via FcγRIIa in an Allele-Specific Way
- Author
-
Aas, V., Sand, K. L., Åsheim, H.-C., Benestad, H. B., and Iversen, J.-G.
- Published
- 2013
- Full Text
- View/download PDF
4. ALTERED ENERGY METABOLISM IN SKELETAL MUSCLE CELLS DERIVED FROM MORBIDLY OBESE INDIVIDUALS: 480 accepted poster
- Author
-
Rustan, A., Bakke, S., Nikolic, N., Hjelmesæth, J., Thoresen, G. H., and Aas, V.
- Published
- 2012
5. Lipid metabolism in human skeletal muscle cells: effects of palmitate and chronic hyperglycaemia
- Author
-
Aas, V., Rokling-Andersen, M., Wensaas, A. J., Thoresen, G. H., Kase, E. T., and Rustan, A. C.
- Published
- 2005
6. Low extracellular Ca2+ reveals a direct effect of interferon-γ on cytosolic Ca2+ in human neutrophils
- Author
-
AAS, V., LARSEN, K., and IVERSEN, J. G.
- Published
- 1998
7. Electrical pulse stimulation of cultured skeletal muscle cells as a model forin vitroexercise - possibilities and limitations
- Author
-
Nikolić, N., primary, Görgens, S. W., additional, Thoresen, G. H., additional, Aas, V., additional, Eckel, J., additional, and Eckardt, K., additional
- Published
- 2016
- Full Text
- View/download PDF
8. Electrical pulse stimulation of cultured skeletal muscle cells as a model for in vitro exercise - possibilities and limitations.
- Author
-
Nikolić, N., Görgens, S. W., Thoresen, G. H., Aas, V., Eckel, J., and Eckardt, K.
- Subjects
SKELETAL muscle ,MUSCLE contraction ,NEURAL stimulation ,METABOLISM ,EXERCISE - Abstract
The beneficial health-related effects of exercise are well recognized, and numerous studies have investigated underlying mechanism using various in vivo and in vitro models. Although electrical pulse stimulation ( EPS) for the induction of muscle contraction has been used for quite some time, its application on cultured skeletal muscle cells of animal or human origin as a model of in vitro exercise is a more recent development. In this review, we compare in vivo exercise and in vitro EPS with regard to effects on signalling, expression level and metabolism. We provide a comprehensive overview of different EPS protocols and their applications, discuss technical aspects of this model including critical controls and the importance of a proper maintenance procedure and finally discuss the limitations of the EPS model. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
9. Skeletal muscle lipid accumulation in type 2 diabetes may involve the liver X receptor pathway
- Author
-
Kase, E.T., Wensaas, A.J., Aas, V., Højlund, Kurt, Levin, K., Thoresen, G.H., Beck-Nielsen, Henning, Rustan, A.C., and Gaster, M.
- Subjects
Sulfonamides ,Hydrocarbons, Fluorinated ,Anticholesteremic Agents ,Gene Expression ,Receptors, Cytoplasmic and Nuclear ,Middle Aged ,Lipid Metabolism ,Orphan Nuclear Receptors ,DNA-Binding Proteins ,Glucose ,Diabetes Mellitus, Type 2 ,Humans ,lipids (amino acids, peptides, and proteins) ,Obesity ,Muscle, Skeletal ,Cells, Cultured ,Glycogen - Abstract
Liver X receptors (LXRs) are important regulators of cholesterol and lipid metabolism and are also involved in glucose metabolism. However, the functional role of LXRs in human skeletal muscle is at present unknown. This study demonstrates that chronic ligand activation of LXRs by a synthetic LXR agonist increases the uptake, distribution into complex cellular lipids, and oxidation of palmitate as well as the uptake and oxidation of glucose in cultured human skeletal muscle cells. Furthermore, the effect of the LXR agonist was additive to acute effects of insulin on palmitate uptake and metabolism. Consistently, activation of LXRs induced the expression of relevant genes: fatty acid translocase (CD36/FAT), glucose transporters (GLUT1 and -4), sterol regulatory element-binding protein-1c, peroxisome proliferator-activated receptor-gamma, carnitine palmitoyltransferase-1, and uncoupling protein 2 and 3. Interestingly, in response to activation of LXRs, myotubes from patients with type 2 diabetes showed an elevated uptake and incorporation of palmitate into complex lipids but an absence of palmitate oxidation to CO(2). These results provide evidence for a functional role of LXRs in both lipid and glucose metabolism and energy uncoupling in human myotubes. Furthermore, these data suggest that increased intramyocellular lipid content in type 2 diabetic patients may involve an altered response to activation of components in the LXR pathway.
- Published
- 2005
10. Reduced lipid oxidation in skeletal muscle from type 2 diabetic subjects may be of genetic origin::evidence from cultured myotubes
- Author
-
Gaster, Michael, Rustan, A.C., and Aas, V.
- Published
- 2004
11. Metabolic switching of human skeletal muscle cells in vitro
- Author
-
Thoresen, G.H., primary, Hessvik, N.P., additional, Bakke, S.S., additional, Aas, V., additional, and Rustan, A.C., additional
- Published
- 2011
- Full Text
- View/download PDF
12. Benfotiamine increases glucose oxidation and downregulates NADPH oxidase 4 expression in cultured human myotubes exposed to both normal and high glucose concentrations
- Author
-
Fraser, D. A., primary, Hessvik, N. P., additional, Nikolić, N., additional, Aas, V., additional, Hanssen, K. F., additional, Bøhn, S. K., additional, Thoresen, G. H., additional, and Rustan, A. C., additional
- Published
- 2011
- Full Text
- View/download PDF
13. Leukemia inhibitory factor reduces contractile function and induces alterations in energy metabolism in isolated cardiomyocytes
- Author
-
FLORHOLMEN, G, primary, AAS, V, additional, RUSTAN, A, additional, LUNDE, P, additional, STRAUMANN, N, additional, EID, H, additional, ODEGAARD, A, additional, DISHINGTON, H, additional, ANDERSSON, K, additional, and CHRISTENSEN, G, additional
- Published
- 2004
- Full Text
- View/download PDF
14. Interferon‐gamma modulates cytosolic free calcium in human neutrophilic granulocytes
- Author
-
Røtnes, J. S., primary, Aas, V., additional, and Iversen, J. G., additional
- Published
- 1994
- Full Text
- View/download PDF
15. C-Reactive Protein Triggers Calcium Signalling in Human Neutrophilic Granulocytes via Fcγ RIIa in an Allele-Specific Way.
- Author
-
Aas, V., Sand, K. L., Åsheim, H.‐C., Benestad, H. B., and Iversen, J.‐G.
- Subjects
- *
C-reactive protein , *CELLULAR signal transduction , *NEUTROPHILS , *GRANULOCYTES , *ALLELES , *CD antigens , *INFLAMMATION , *GENE expression - Abstract
C-reactive protein (CRP) binds to Fcγ-receptors, FcγRIIa ( CD32) with high affinity and to Fcγ RIa ( CD64) with low affinity. The binding to CD32 has been shown to be allele specific, that is, it binds to R/ R131 but not to H/ H131. Little is known about the cooperation of CRP and neutrophilic granulocytes ( PMNs) in inflammatory reactions. The purpose of the present study was to examine CRP signalling in human PMNs, and whether this signalling is also allele specific. Cytosolic calcium of PMN was measured in a single-cell digital imaging system. Receptor expression and polymorphism were studied by real-time RT- PCR, flow cytometry and standard PCR. C-reactive protein induced cytosolic calcium signals in PMNs from homozygote R/ R131donors, but not in PMNs from heterozygote R/H131 donors. However, after the heterozygote PMNs had been incubated with IFN-γ (100 U/ml) for 2 h, both the proportion of cells responding and the size of the CRP-induced calcium signals increased. IFN-γ increased mRNA expression of CD64 about fivefold and surface protein expression of CD64 about fourfold. The calcium signal elicited by CRP was augmented by PMN adhesion to fibronectin, but almost totally abrogated by sphingosine kinase inhibitors. The signals were partly dependent on calcium influx. In conclusion, calcium signalling instigated by CRP in human PMN is Fcγ RIIa allele specific, as R/ R131 responded to CRP, whereas R/ H131 did not. However, increased expression of FcγRIa ( CD64), stimulated by IFN-γ, can augment calcium signalling by CRP in low-responders. This suggests that the state of the PMNs, as well as the genetic origin, affect sensitivity for CRP. [ABSTRACT FROM AUTHOR]
- Published
- 2013
- Full Text
- View/download PDF
16. Benfotiamine increases glucose oxidation and downregulates NADPH oxidase 4 expression in cultured human myotubes exposed to both normal and high glucose concentrations.
- Author
-
Fraser, D., Hessvik, N., Nikolić, N., Aas, V., Hanssen, K., Bøhn, S., Thoresen, G., and Rustan, A.
- Abstract
The aim of the present work was to study the effects of benfotiamine (S-benzoylthiamine O-monophosphate) on glucose and lipid metabolism and gene expression in differentiated human skeletal muscle cells (myotubes) incubated for 4 days under normal (5.5 mM glucose) and hyperglycemic (20 mM glucose) conditions. Myotubes established from lean, healthy volunteers were treated with benfotiamine for 4 days. Glucose and lipid metabolism were studied with labeled precursors. Gene expression was measured using real-time polymerase chain reaction (qPCR) and microarray technology. Benfotiamine significantly increased glucose oxidation under normoglycemic (35 and 49% increase at 100 and 200 μM benfotiamine, respectively) as well as hyperglycemic conditions (70% increase at 200 μM benfotiamine). Benfotiamine also increased glucose uptake. In comparison, thiamine (200 μM) increased overall glucose metabolism but did not change glucose oxidation. In contrast to glucose, mitochondrial lipid oxidation and overall lipid metabolism were unchanged by benfotiamine. The expression of NADPH oxidase 4 (NOX4) was significantly downregulated by benfotiamine treatment under both normo- and hyperglycemic conditions. Gene set enrichment analysis (GSEA) showed that befotiamine increased peroxisomal lipid oxidation and organelle (mitochondrial) membrane function. In conclusion, benfotiamine increases mitochondrial glucose oxidation in myotubes and downregulates NOX4 expression. These findings may be of relevance to type 2 diabetes where reversal of reduced glucose oxidation and mitochondrial capacity is a desirable goal. [ABSTRACT FROM AUTHOR]
- Published
- 2012
- Full Text
- View/download PDF
17. Interferon-t elicits a G-protein-dependent Ca^2^+ signal in human neutrophils after depletion of intracellular Ca^2^+ stores
- Author
-
Aas, V., Larsen, K., and Iversen, J.-G.
- Published
- 1999
- Full Text
- View/download PDF
18. 40 EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004
- Author
-
Veitenhansl, M., Stegner, K., Hierl, F-X, Dieterle, C., Feldmeier, H., Gutt, B., Landgraf, R., Garrow, A. P., Vileikyte, L., Findlow, A., Waterman, C., Boulton, A. J. M., Shankhdhar, K., Shankhdhar, L., Shankhdhar, U., Petrova, N. L., Foster, A. V. M., Edmonds, M. E., Ferraresi, R., Caravaggi, C., Giglio, R., Cavaiani, P., Pogliaghi, I., Sommariva, E., Katz, I. A., Harlan, A., Miranda-Palma, B., Prieto-Sanchez, L., Armstrong, D. G., Bowker, J. H., Mizel, M. S., Cernea, S., Wohlgelernter, J., Kidron, M., Modi, P., Raz, I., Arbit, E., Nosek, L., Kapitza, C., Beckett, P., Gelfand, R., Goldberg, M., Heise, T., Testa, M. A., Turner, R. R., Hayes, J. F., Scranton, R. E., Simonson, D. C., Yang, Y-W, Hsu, Y-J, Naujok, O., Francini, F., Jorns, A., Tiedge, M., Lenzen, S., Abdel-Wahab, Y. H. A., Marenah, L., Orr, D. F., Shaw, C., Flatt, P. R., Chokkalingam, K., Mansell, P. I., Clausen, P., Ekbom, P., Damm, P., Feldt-Rasmussen, U., Nielsen, B., Mathiesen, E. R., Feldt-Rasmussen, B., Dewan, S., Da Silva, N., Ternan, P. Mc, Leong, K. S., Wilding, J. P. H., Asatiani, N., Kurashvili, R., Dundua, M., Shelestova, E., Pagava, K., Ramazashvili, M., Hod, M., Smirnov, S., Petersen, J. L. A., Justesen, T. I., Ringholm Nielsen, L., Muller, C., Hojlund, K., Wensaas, A., Kase, E. T., Aas, V., Rustan, A. C., Thoresen, G. H., Levin, K., Beck-Nielsen, H., Gaster, M., Im, S-S, Kang, S-Y, Kim, S-Y, Ahn, Y-H, Lihn, A. S., Schmoll, D., Werner, T., Kienitz, A., Meyer, M., Barthel, A., Ailett, F., Sutherland, C., Walther, R., Grempler, R., Sasson, S., Reich, R., Tenenbaum, T., Alpert, E., Anfossi, G., Russo, I., Traversa, M., Massucco, P., Mattiello, L., Doronzo, G., Trovati, M., Lally, S., Tan, C. Y., Owens, D., Tomkin, G. H., Porchay, I., Pean, F., Bellili, N., Betoulle, D., Balkau, B., Tichet, J., Marre, M., Fumeron, F., Group D.E.S.I.R., Chatellier, G., Alhenc-Gelas, F., Diabhycar, Study Group, Nichols, G. A., Brown, J. B., Hayes, R. P., Bowman, L., Drexel, H., Saely, C. H., Marte, T., Benzer, W., Langer, P., Hoefle, G., Moll, W., Aczel, S., Karagiannis, E., Lubben, G., Urquhart, R., Edwards, G., Bruce, S., Howlett, H. S. C., Cugnardey, N., Turner, K. C., Park, J-S, Fiedorek, F. T., Avogaro, A., Gallo, A., Pinton, P., Rizzuto, R., Murphy, E., Ceolotto, G., Caterson, I., Guy-Grand, B., Hill, J., Barone, M., Aiello, A., Allochis, G., Borzi, V., Cannata, F., Caronna, S., D Avanzo, A., Elli, R., Formoso, G., Paroli, A., Scardapane, R., Sorichetti, P., Tatti, P., Viviani, G., Santeusanio, F., Italian Repaglinide Study Group, Manzella, D., Grella, R., Abbatecola, A. M., Paolisso, G., Sondergaard, L. G., Monster, T. B. M., Johnsen, S. P., Olsen, M. L., Mclaughlin, J. K., Sorensen, H. T., Lervang, H. H., Rungby, J., Lyssenko, V., Fredriksson, J., Almgren, P., Anevski, D., Orho-Melander, M., Sjogren, M., Tuomi, T., Groop, L., Jaziri, R., Aubert, R., Tuomilehto, J., Hu, G., Jousilahti, P., Peltonen, M., Lindstrom, J., Laina, A., Alevizaki, M., Philippou, G., Souvatzoglou, A., Anastasiou, E., Alba, S., Metcalf, B. S., Voss, L. D., Jeffery, A. N., Wilkin, T. J., Gluimer, C., Colagiuri, S., Vistisen, D., Borch-Johnsen, K., Haynes, A., Bower, C., Bulsara, M. K., Jones, T. W., Davis, E. A., Mortensen, H. B., Hougaard, P., Holl, R., Swift, P., Pociot, F., Knip, M., Hansen, L., Szadkowska, A., Pietrzak, I., Zmyslowska, A., Wyka, K., Bodalski, J., Holl, R. W., Swift, R., Hougaard, R., Gerstl, E-M, Engelsberger, I., Rabl, W., Rosenbauer, J., Grobe, H., Hofer, S. E., Krause, U., DPV-Wiss-Study Group, Dabelea, D., Morgan, T., Pettitt, D. J., Dolan, L., Mayer-Davis, E. J., Pihoker, C., Hillier, T. A., Imperatore, G., Ruggiero, A., Hamman, R. E., Stylianou, A., Tentolouris, N., Perrea, D., Tselepis, A. D., Lourida, E., Kitsou, E., Katsilambros, N., Vedovato, M., Dodesini, A. R., Lepore, G., Tiengo, A., Trevisan, R., Penno, G., Miccoli, R., Pucci, L., Lucchesi, D., Bandinelli, S., Fotino, C., Triscornia, S., Baldassari, E., Del Prato, S., Reboldi, P., Santeusanio, E., Fuller, J., Langham, R. G., Gow, R. M., Zhang, Y., Kelly, D. J., Christensen, P. K., Parving, H-H, Gilbert, R. E., Chibalin, A. V., Zhong, Z., Kotova, O., Davidescu, A., Ehren, I., Ekberg, K., Wahren, J., Wassef, L., Buckley, A. J., Rooney, K. B., Briody, J., Thompson, M., Ozanne, S. E., Thompson, C. H., Chamson-Reig, A., Summers, K., Arany, E. J. R., Hill, D. J., Solerte, S. B., Gazzaruso, C., Locatelli, E., Precerutti, S., Schifino, N., Ferrari, E., Fioravanti, M., Phenekos, C. V., Ginis, A., Fragaki, I., Chalkiadaki, M., Tzioras, C., Powell, L. A., Mcguire, G. M., Jewhurst, V., Trimble, E. R., Rasmussen, B. M., Vessby, B., Uusitupa, M., Berglund, L., Pedersen, E., Riccardi, G., Rivellese, A. A., Tapsell, L., Hermansen, K., Kanwu, Study Group, Da Silva Xavier, G., Rutter, J., Rutter, G. A., Briaud, I. M., Lingohr, M. K., Dickson, L. M., Mccuaig, J. R., Lawrence, J. C., Rhodes, C. J., Wikstrom, J. D., Katzman, S. M., Shirihai, O. S., Yang, J., Deng, S., Wang, X., Hessner, M. J., Wu, J., Wong, R. K., Sukumvanich, S., Markman, J. F., Naji, A., Wolf, B. A., Gao, Z., Rubi, B., Del Arco, A., Satrustegui, J., Maechler, P., Del Guerra, S., Lupi, R., Bugliani, M., Sbrana, S., Torri, S., Boggi, U., Vistoli, F., Mosca, F., Marchetti, P., Rennings, A. J. M., Smits, P., Stewart, M. W., Tack, C. J. J., Li, L., Nystrom, T., Gutniak, M., Ahren, B., Holst, J., Sjoholm, A., Gomes, M. B., Cailleaux, S., Tibirica, E., Albertini, J-P, Chen, H., Mather, R., Valensi, P. E., Chisalita, S. I., Arnqvist, H. J., Kraenkel, N., Adams, V., Linke, A., Gielen, S., Schuler, G., Humbrecht, R., Cipollone, F., Iezzi, A., Fazia, M., Pini, B., Cucurullo, C., Cesare, D., Schmidt, A. M., Mazurek, T., Zang, L. F., Mannion, J., Diehl, J., Martin, J., Martella, A., Zalewski, A., Shi, Y., Otter, W., Winter, M., Doering, W., Standi, E., Schnell, O., Kragelund, C., Kober, L., Faber, J., Hildebrandt, P., Steffensen, R., Pankowska, E., Szypowska, A., Lipka, M., Herwig, J., Scholl-Schilling, G., Bohles, H., Robertson, K. J., Schonle, E., Gucev, Z., Mordhorst, L., Tamer, S. C., Gall, M-A, Ludvigsson, J., Hoogma, R. P. L., Hammond, P. J., Gomis, R., Kerr, D., Bruttomesso, D., Bouter, P., Wiefels, K. J., La Calle, H., Schweitzer, D. H., Pfohl, M., Torlone, E., Krinelke, L. G., 205-Nations Study Group, Conget, I., Storms, F., Rodriguez, J., Leperlier, C., Davies, M., At Lantus, Study Group, Peter, R., Luzio, S. D., Dunseath, G., Miles, A., Hare, B., Backx, K., Pauvaday, V., Owens, D. R., Caselli, A., Marfia, G. A., Battista, C., Veves, A., Spallone, V., Uccioli, L., Gonzalez, J. S., Peyrot, M. F., Rubin, R. R., Leventhal, H., Scheffler, N., Ulbrecht, J. S., Cavanagh, P. R., Boulton, A. J., Perrin, N. A., Oglesby, A., Bastyr, E. J., Ziegler, D., Siekierka-Kleiser, E., Meyer, B., Schweers, M., Selvarajah, D., Wilkinson, I. D., Emery, C. J., Shaw, P. J., Griffiths, P. D., Tesfaye, S., Obrosova, I. G., Arezzo, J., Phillips, K., Fidarestat Study Group, Gribble, F. M., Williams, L., Reimann, F., Iakoubov, R., Whiteside, C., Brubaker, P. L., Acitores, A., Gonzalez, N., Sancho, V., Valverde, I., Villanueva-Penacarrillo, M. L., Martin-Duce, A., Trigo, M. V., Arnes, L., Burkart, V., Ichino, N., Ohashi, A., Klein, B. S., Paxian, S., Schmid, R., Karlsen, A. E., Heding, P. E., Frobose, H., Ronn, S. G., Kruhoffer, M., Orntoft, T. F., Nerup, J., Mandrup-Poulsen, T., Billestrup, N., Cardozo, A. K., Ortis, F., Feng, Y-M, Rasschaert, J., Eylen, F., Storling, J., Herchuelz, A., Eizirik, D. L., Wang, H., Kouri, G., Wollheim, C. B., Ribaux, P., Hammar, E., Parnaud, G., Rouiller, D., Bosco, D., Halban, P., Midthjell, K., Carlsson, S., Grill, V., Lau, C., Farch, K., Glumer, C., Tetens, I., Jorgensen, T., Tillin, T., Forouhi, N., Mckeigue, P., Chaturvedi, N., Zethelius, B., Hales, C. N., Berne, C., Coleman, R. L., Stevens, R. J., Holman, R. R., Christensen, J. O., Sandbak, A., Lauritzen, T., Irwin, N., Gault, V. A., Green, B. D., Harriott, P., O Harte, F. P. M., Bouman, S. D., Urso, B., Brand, C. L., Rolin, B., Ribel, U., Schaffer, L., Maggs, D. G., Ceriello, A., Frias, J. P., Wang, Y., Ruggles, J. A., Kolterman, O. G., Piconi, L., Weyer, C., Want, L. L., Ratner, R. E., Uwaifo, G. I., Thornberry, N. A., Eiermann, G., Kim, D., Lankas, G., Leiting, B., Li, Z., Lyons, K., Petrov, A., Sinha Roy, R., Woods, A., Woods, J., Zhang, B. B., Fisher, M., Moller, D. E., Weber, A. E., Dreyer, M., Bellin, C., Schmitz, V., Roesen, R., Nescheret, A. P., Bose, A. K., Mocanu, M. M., Carr, R. D., Yellon, D. M., Manolopoulos, K., Born, S., Wagner, A., Jeziorska, M., Ben Drief, A., Bashir, M., Tomlinson, D., Malik, R. A., Zeymer, U., Schwarzmaier-D Assie, A., Petzinna, D., Chiasson, J-L, Stratton, I. M., Af Bjorkesten, C-G, Fagerudd, J., Rosengard-Barlund, M., Forsblom, C., Pettersson-Fernholm, K., Waden, J., Saraheimo, M., Ronnback, M., Thorn, L., Groop, P-H, Mollsten, A., Svensson, M., Kockum, I., Rudberg, S., Brismar, K., Dahlquist, G., Hovind, P., Hansen, T. K., Tarnow, L., Thiel, S., Jensen, B. R., Flyvbjerg, A., Kankova, K., Hertlova, M., Krusova, D., Schwenke, S., Ott, J., Thom, S. A. M., Mistry, P., Sjolie, A., Larsen, B., Witt, N., Hughes, A. D., Samira, H. H., Lahiry, S., Howlader, S. R., Parveen, S., Azad Khan, A. K., Clarke, P. M., Gray, A., Stevens, R., Holman, R., Phillips, L., Phillips, P. J., Chittleborough, C., Baldock, K., Taylor, A., North West Adelaide Health Study Team, Davis, W. A., Davis, T. M. E., Knuiman, M. W., Hendrie, D., Worthley, D., Nicolucci, A., Pellegrini, F., Berardis, G., Franciosi, M., Belfiglio, M., Rossi, M. C. E., Sacco, M., Valentini, M., Richardson, C. C., Jones, P., Persaud, S., Hussain, K., Clark, A., Christie, M. R., Gniuli, D., Hribal, M. L., Accili, D., Khan, M., Zervou, S., Cheung, L., Abouna, S., Ifandi, V., Pelengaris, S., Luco, R. F., Ferrer, J., Ma, D., Shield, J. P. H., Dean, W., Leclerc, I., Knauf, C., Burcelin, R., Kelsey, G., Powers, A. C., Shostak, A., Ferrara, N., Poffenberger, G., Jerome, W. G., Brissova, M., Geloneze, S. R., Tambascia, M. A., Pareja, J. C., Chaim, E., Silveira, H. V., Geloneze, B., Ravikumar, B., Carey, P. E., Snaar, J. E., Dheelchand, D., Cook, D. B., Neely, D., Taylor, G., Morris, P. G., Taylor, R., Stears, A. J., Masding, M. G., Wootton, S. A., Sandeman, D. D., Klimes, I., Wein, S., Gasperikova, D., Ukropec, J., Wiernsperger, N., Sebokova, E., Manco, M., Mingrone, G., Granato, L., Greco, A. V., Nanni, G., Castagneto, M., Vidal, H., Calvani, M., Ferrannini, E., Alvarsson, M., Sundkvist, G., Lager, I., Henricsson, M., Berntorp, K., Fernqvist-Forbes, E., Steen, L., Orn, T., Shutler, S., Bianchi-Biscay, M., Rosenstock, J., Sugimoto, D., Strange, P., Stewart, J., Soltes Rak, E., Dailey, G., Kloos, C., Muller, U., Samann, A., Femerling, M., Risse, A., Jecht, M., Haak, T., Garg, R., Lawrence, I. G., Akinsola, M. O., Davies, M. J., Mcnally, P. G., Garber, A. J., Kim, H., Draeger, E., Aydin, L., Sengul, A., Kurklu, A., Ucak, S., Basat, O., Seber, S., Altuntas, Y., Jin, J., Yu, Y., Yu, H., Zhang, X., Mattoo, V., Eckland, D., Widel, M., Duran, S., Fajardo, C., Strand, J., Knight, D., Oakley, D., Tan, M., Sato, A., Nagao, M., Aki, N., Nakagami, T., Iwamoto, Y., Zhou, Z., Li, X., Huang, G., Yan, X., Yang, L., Peng, J., Wang, J., Tan, S., Tang, W., Furnsinn, C., Brunmair, B., Wagner, L., Gras, F., Artwohl, M., Zierhut, B., Waldhausl, W., Shine, B. L., Hopkins, D., Anand, V., Lim, E., Raval, U., Sharp, P., Corder, R., Lipkin, D., Lahiri, A., Bartnik, M., Ryden, L., Ferrari, R., Malmberg, K., Pyorala, K., Simoons, M. L., Standl, E., Soler-Soler, J., Ohrvik, J., Euro Heart Survey Investigators, Bruce, D. G., Starkstein, S. E., Schauer, U. J. W., Astrup, A. S., Pietraszek, L., Nielsen, F. S., Rossing, P., Ali, S., Smidt, U. M., Yokoyama, H., Pavkov, M. E., Knowler, W. C., Bennett, P. H., Nelson, R. G., Lopez-Alba, A., Morcillo, L., Caballero, A., Montoya, L., Jimenez, A., Maceira, B., Lewis, J. B., Ravid, M., Wajman, A., Tadgell, C., Remuzzi, G., Hunsicker, L. G., Wessman, M., Taskinen, M-R, FinnDiane Study Group, Pugliese, G., Amadio, L., Menini, S., Oddi, G., Ricci, C., Iacobini, C., Pricci, F., Sorcini, M., Pesce, C., Migliaccio, E., Giorgio, M., Pelicci, P., Di Mario, U., Lassila, M., Jandeleit-Dahm, K., Seah, K. K., Calkin, A. C., Allen, T. J., Cooper, M. E., Lopes Faria, J. M., Cavakcanti, T. C., Silva, K. C., Ferrari, A. L., Lopes Faria, J. B., Cellek, S., Foxwell, N. A., Cotter, M. A., Cameron, N. E., Tennagels, N., Jordan, H., Stahl, P., Voss, M. D., Welte, S., Werner, U., Lehmann, R., Moeschel, K., Baumgartner, F., Oeckinghaus, A., Beck, A., Weigert, C., Hennige, A., Schleicher, E. D., Haring, H. U., Mussig, K., Staiger, H., Haring, H-U, Natalicchio, A., Laviola, L., Tullio, C., Renna, L., Giorgino, R., Giorgino, F., Falasca, M., Maffucci, T., Park, D., Kang, S., Song, J., Lee, D., Lee, Y., Hariharan, N., Kunselman, L., Gu, L., Sasseville, V., Harrity, T., Cheng, P. T. W., Pratley, R. E., Schweizer, A., Mills, D., Kim, T-H, Song, X-L, Poelje, P. D., Potter, S. C., Dang, Q., Fujitaki, J. M., Linemeyer, D. L., Landau, B. R., Erion, M. D., Pankop, M., Golay, A., Despres, J., Sjostrom, L., Lawlor, D. L., Legg, K. T., Ur, E., Houweling, S. T., Kleefstra, N., Meyboom-De Jong, B., Bilo, H. J. G., Schlomer, G. J., Meyer, G., Kasper, J., Muhlhauser, I., Young, B., Taylor, J., Friede, T., Hollis, S., Mason, J., Long, A., Gambling, T., Pauline, L., Burns, E., New, J., Gibson, M., Betteridge, D. J., Leiter, L. A., Audit, Investigators, Whitty, P. M., Eccles, M. P., Hawthorne, G., Grimshaw, J., Steen, I. N., Vanoli, A., Wood, L., Speed, C., Mcdowell, D., Rewers, M., Maahs, D., Wadwa, R., Eckel, R., Tracy, R., Pfutzner, A., Strotmann, H-J, Schulze, J., Hohberg, C., Pahler, S., Forst, T., Ambery, P. D., Sydall, H., Cooper, C., Dennison, E., Sayer, A. Aihie, Barker, D., Phillips, D., Lalic, N. M., Ostojic, M., Lalic, K., Zamaklar, M., Jotic, A., Ilic, M., Rajkovic, N., Lukic, L., Milicic, T., Verges, B., Zeller, M., Steg, P. G., Beer, J. C., Brisard, C., Brindisi, M. C., Dentan, G., Laurent, Y., Janin-Manificat, L., Makki, H., Ravisy, J., Cottin, Y., Ajjan, R. A., Grant, P. J., Futers, T. S., Brown, J. M., Carter, A. M., Rasmussen, M. S., Bruun, J. M., Pedersen, S. B., Richelsen, B., Dietze-Schroeder, D., Sell, H., Koenen, M., Eckel, J., Delporte, M-L L., Bauche, I. B., Brichard, S. M., Ait El Mkadem, S., Rezsohazy, R., Tsiotra, P. C., Tsigos, C., Gatsiou, C., Raptis, S. A., Walker, C. G., Bryson, J. M., Hancock, D. P., Caterson, I. D., Takahashi, N., Hatakeyama, H., Kasai, H., Gauthier, B. R., Iezzi, M., Fukuda, M., Duhamel, D. L., Ravier, M. A., Dufer, M., Neye, Y., Krippeit-Drews, P., Hennige, A. M., Sausbier, U., Arntz, C., Sausbier, M., Neuhuber, W., Ruth, P., Drews, G., Beauvois, M. C., Rolland, J-F, Jonas, J-C, Merezak, C., Henquin, J-C, Gilon, P., Jabin Gustafsson, A., Dzabic, M., Islam, M. S., Vaxillaire, M., Cheyssac, C., Dina, C., Vasseur-Delannoy, V., Lepretre, F., Siddiq, A., Froguel, P., Neve, B., Fernandez-Zapico, M. E., Ashkenazi-Katalan, V., Urrutia, R., Melloul, D., Froguel, R., Poulsen, P., Wojtaszewski, J., Richter, E., Vaag, A., Granhall, C., Renstrom, E., Luthman, H., Isomaa, B., Gloyn, A. L., Edghill, E. L., Pearson, E. R., Mackay, D. J. G., Temple, I. K., Noyes, K., Freedenberg, D., Gillespie, K. M., Lambert, A. P., Gale, E. A., Ellard, S., Hattersley, A. T., Fanelli, C. G., Porcellati, F., Rossetti, P., Busciantella, N. R., Billi, C., Burrin, D. G., Bolli, G. B., Bingham, E. M., Dunn, J., Sutcliffe-Goulden, J., Marsden, P., Amiel, S., Davis, R. E., Kennedy-Martin, T., Peters, J. R., Wittrup-Jensen, K. U., Mcewan, P., Morrissey, M., Currie, C. J., Akram, K., Pedersen-Bjergaard, U., Thorsteinsson, B., Pibernik-Okanovic, M., Peros, K., Begic, D., Szabo, S., Metelko, Z., Vlaiculescu, M. V., Calota, I., Busila, T., Bruckner, I., Giannakopoulou, D. F., Lindner, H. D., Hrachovinova, T., Fejfarova, V., Csemy, L., Malcomson, J., Campbell, M., Pandolfi, A., Giardinelli, A., Di Tomo, P., Di Silvestre, S., Di Fulvio, P., Capani, F., Consoli, A., Roesen, P., Patruno, A., Grilli, A., Capani, R., Felaco, M., Boner, G., Mccarroll, K., Brenner, B. M., Zeeuw, D., Kowey, P., Shahinfar, S., Crow, R. S., Iso, K., Kuboki, K., Tada, H., Yoshino, G., Schjoedt, K. J., Andersen, S., Distiller, L. A., Degenhardt, T. P., Szabo, J. R., Khalifah, R. G., Schotzinger, R. J., Achenbach, P., Knopff, A., Naserke, H., Ziegler, A. G., Bonifacio, E., Valera, L., Jardin, B., Roche, S., Lampasona, V., Pugniere, M., Roquet, F., Granier, C., Laune, D., Afifiyan, F., Cheung, R., Yantha, J., Jackowski, G., Dosch, H-M, Nakanishi, K., Kogawa, N., Komatsu, Y., Fontes, G., Imamura, T., Ilic, C., Puech, C., Ktorza, A., Bataille, D., Dalle, S., Sorensen, H., Fosgerau, K., Gelling, R. W., Nishimura, E., Andersen, B., Madsen, P., Lau, J., Streicher, R., Wagner, K., Vettermann, R., Potterat, O., Renard, E., Panteleon, A. E., Kolopp, M., Rebrin, K., Steil, G., Steil, G. M., Hariri, F., Darwin, C., Saad, M. F., Buckingham, B., Kunselman, B., Wong, L., Istoc, E., Leach, J., Purvis, R., Monfre, S. L., Fischer, J. S., Garg, S., Ahmann, A. J., Ruchti, T. L., Gandhi, G. Y., Nuttall, G. A., Mullany, C. J., Schaff, H. V., Williams, B. A., Rizza, R. A., Mcmahon, M. M., Gates, G., Mentel, J., Smith, R., Crook, J., Hosszufalusi, N., Vatay, A., Palik, E., Fust, G., Karadi, I., Romics, L., Panczel, P., Aurich, K., Voelker, U., Braun, A., Muller, U. A., Nguyen, L. L., Kriketos, A. D., Hancock, D., Denver, G. S., Uceyler, N., Schutt, M., Lesch, K-P, Mossner, R., Sommer, C., Seda, O., Liska, F., Kazdova, L., Sedova, L., Krenova, D., Zima, T., Tremblay, J., Kren, V., Hamet, P., Kloting, N., Follak, N., Kloting, I., Dessapt, C., Dei Cas, A., Baradez, M-O, Hayward, A., Thomas, S., Viberti, G., Gnudi, L., Gale, C. P., Jandeleit-Dahm, K. A. M., Thallas, V., Thomas, M. C., Candido, R., Burns, W. C., Forbes, J. M., Shymanskyy, I., Kuchmerovska, T., Klimenko, A., Jaeckel, E., Manns, M. P., Boehmer, H., Hedrich, H. J., Tellez, N., Montolio, M., Estimes, E., Rodriguez-Mulero, S., Soler, J., Montanya, E., Liu, Y., Chen, J., Rowlands, D., Chan, H., Simeonov, I. S., Anthony, K., Bingham, E., Marsden, P. K., Amiel, S. A., Malik, R. J. A., Zelaya, F., Williams, S., Brammer, M., Mountjoy, P. D., Bailey, S. J., Shaw, J. E., Sicree, R., Dunstan, D., Cameron, A., Zimmet, P. Z., Hewitt, S., Graff-Iversen, S., Assah, F. K., Fezeu, L., Kengne, A., Awah, P. K., Mbanya, J. N., Shu, J. A., Kamadjeu, R. K. K., Kiawi, E. C., Mbanya, J., Assah, F., Kerenyi, Z., Peterfalvi, A., Bosnyak, Z., Madarasz, E., Tabak, A. G., Szantho, J., Rakoczi, I., Tamas, G., Di Bartolo, P., Valpiani, G., Di Martino, M., Scaramuzza, A., Saragoni, S., Degli Esposti, E., Gudbjornsdottir, S., Cederholm, J., Nilsson, P., Eliasson, B., Miettinen, M. E., Miettinen, J., Nan, H. R., Dong, Y., Gao, W., Sun, B., Wang, N., Fu, F., Shi, H., Ding, M., Lorenzo, C., Serrano-Rios, M., Martinez-Larrad, M. T., Gonzalez-Sanchez, J. L., Seclen, S., Villena, A., Gonzalez-Villalpando, C., Williams, K., Stern, M. P., Haffner, S. M., Sakurai, M., Miura, K., Kita, Y., Takamura, T., Ota, T., Ishizaki, M., Morikawa, Y., Nakagawa, H., Szybinski, Z., Szurkowska, M., Mardarowicz, G., Lopatynski, J., Gilis-Januszewska, A., Szafraniec, K., Nicer, T., Kwon, H-S, Lee, J-H, Lee, H-J, Park, Y-M, Choi, Y-H, Kim, S-R, Jang, S-A, Song, B-R, Yoon, K-H, Kim, H-S, Lee, W-C, Cha, B-Y, Lee, K-W, Son, H-Y, Kang, S-K, Jorgensen, M. E., Moustgaard, H., Bjerregaard, P., Ebara, F., Dunstan, D. W., Salmon, J., Owen, N., Cameron, A. J., Welborn, T. A., Armstrong, T., Jolley, D., Galtier, F., Deschamps, V., Borys, J-M, Lasfargues, G., Andre, P., Born, C., Royer, B., Wilpart, E., Cailleau, M., Eschwege, E., Timar, R. Z., Serban, V., Vlad, A. R., Diaconu, L. F., Rosu, M., Olari, O., Sima, A. C., Qiao, Q., Chappuis, B., Diem, P., Christ, E. R., Iafusco, D., Prisco, F., Gemma, C., Mattera, S., Sanges, M., Menneila, C., Sommese, L., Jarosz-Chobot, P., Polanska, J., Feltbower, R. G., Mckinney, P. A., Stephenson, C. R., Bodansky, H. J., Icks, A., Du Prel, J-B, Grabert, M., Giani, G., Kyvik, K. O., Skytthe, A., Ioacara, S., Farcasiu, E., Bradescu, O., Guja, C., Scutaru, G., Savu, O., Ionescu-Tirgoviste, C., Ola, T. O., Hawa, M. I., Buzzetti, R., Scherbaum, W., Kolb, H., Thivolet, C., Hunter, S., Hadden, D., Guntram, S., Leiva, A., Mauricio, D., Pozzilli, P., Leslie, R. D. G., Benediktsson, R., Jonsdottir, A. M., Einarsdottir, A. S., Reynisdottir, I., Aspelund, T., Grant, S. F. A., Thorleifsson, G., Sigurdsson, G., Stefansson, K., Gudnason, V., Wollitzer, A. O., Jovanovic, L., Lobo, P. E., Marti, M. L., Preiti, M. C., Urdaneta, R. F., Juarez, S. S., Schober, E., Thon, A., Rami, B., Hofer, S., Tringham, J. R., Buyukbese, M. A., Sakamoto, Y., Inoue, Y., Matsumoto, H., Oono, K., Tokumasa, Y., Gorter, K. J., Janssen, P. G. H., Stolk, R. P., Hessen, P. A. W., Rutten, G. E. H., Niedermayer, D., Murro, A., Geloneze, S., Coghi, C., Federici, M. Orsini, Benedetti, M. Massi, Koehler, C., Henkel, E., Temelkova-Kurktschiev, T., Stier, U., Ott, P., Siegert, G., Bergmann, S., Hanefeld, M., Leonhardt, W., Sayeed, M. A., Mahtab, H., Khanam, P. A., Banu, A., Rashid, M. A., Mulnier, H., Seaman, H., Lovell, D., Soedamah-Mathu, S., Colhoun, H., Lawrenson, R., Diehm, C., Lange, S., Darius, H., Pittrow, D., Haberl, R., Stritzky, B., Tepohl, G., Allenberg, J. R., Trampisch, H-J, Soinio, M., Marniemi, J., Laakso, M., Lehto, S., Ronnemaa, T., Ito, C., Sasaki, H., Ishida, S., Maeda, R., Barengo, N. C., Lakka, T. A., Kohler, C., Benke, I., Raccah, D., Bailleau, C., Vexiau, P., Vaur, L., Aydin, N., Topsever, P., Filiz, T. M., Dayan, A., Bulgurlu, S., Gebeloglu, N., Demirtunc, R., Dagar, A., Skliros, E., Sotiropoulos, A., Vassibosis, A., Xipnitos, C., Liva, E., Chronopoulos, I., Merkouris, P., Skourtis, S., Pappas, S., Charbonnel, B., Baigts, F., Dumenil, V., Paillasson, S., Baleydier, A., Hanaire, H., Sert, C., Chabrier, G., Rodier, M., Fontaine, P., Kim, J-I, Miyake, Y., Sakai, T., Takamatsu, K., Tomioka, Y., Sugano, H., Murao, S., Shimizu, I., Unwin, N. C., Nag, S., Roglic, G., Connolly, V., Roper, N., Goodwin, J., Kelly, W., Lervang, H-H, Thomsen, R. W., Hundborg, H. H., Schonheyder, H. C., Khalangot, M. D., Gang, H., Tajima, N., Bianchi, C., Giovannitti, M. G., Pellegrini, G., Caricato, F., Bertolotto, A., Corfini, M., Guzder, R., Gatling, W., Byrne, C., Varillas, V. F., Boronat, M., Carrillo, A., La Roche, F., Ojeda, A., Lopez, Y., Marrero, D., Novoa, J., Shahidul Alam Khan, A. K. M., Thaware, P. K., Gangat, I., Howlett, T. A., Jenum, A. K., Holme, I., Birkeland, K. I., Sourij, H., Stoschitzky, K., Klein, W., Roth, M., Dittrich, P., Wascher, T. C., Hilding, A., Eriksson, A-K, Agardh, E. E., Efendic, S., Ostenson, C-G, Levitt, N. S., Bradshaw, D., Salzsieder, E., Freyse, E-J, Rutscher, A., Heinke, P., Augstein, P., Makino, H., Kainou, Y., Konoue, E., Ohno, K., Ebisui, O., Fujii, Y., Kondo, S., Fujiyama, M., Tanaka, K., Takemoto, K., Kida, K., Onuma, Y., Osawa, H., Tuomilehto-Wolf, E., Kinnunen, L., Laine, A-P, Kokko, T., Kakko, T., Hermann, R., Veijola, R., Simell, O., Ilonen, J., Guglielmi, C., Galgani, A., Beretta Anguissola, G., D Avola, D., Bakhtadze, E., Weiss, H., Hedrich, H-J, Wedekind, D., Bilbao, J. R., San Pedro, J. I., Vitoria, J. C., Martul, P., Castano, L., Badenhoop, K., Ramos Lopez, E., Usadel, K. H., Wagner, A. M., Cloos, P. A. C., Stahlhut, M., Bergholdt, R., Ramos, E., Taxvig, C., Vella, A., Smyth, D., Cooper, J. D., Undlien, D. E., Ronningen, K. S., Savage, D. A., Dunger, D. B., Strachan, D. P., Ring, S. M., Todd, J. A., Mironczuk, K., Kretowski, A., Kinalska, I., Nutland, S., Guja, L., Nielsen, L. B., Gammeltoft, S., Schwarz, P. E. H., Towers, W. G., Fischer, S., Mcrae, J. F., Willis, J. A., Scott, R. S., Potter, H. C., Merriman, T. R., Frampton, C. M., George, P. M., Spranger, J., Mohlig, M., Hoffmann, K., Muller, S., Osterhoff, M., Ristow, M., Boeing, H., Pfeiffer, A. F. H., Li, Y., Fisher, E., Burwinkel, B., Schrezenmeir, J., Mager, U., Pulkkinen, L., Lindi, V., Xiu, L. L., Sui, Y., Weng, J. P., Kalis, M., Cilio, C. M., Olde, B., Owman, C., Groop, L. C., Leveen, P., Da Ros, R., Assaloni, R., Maier, A., Quagliaro, L., Zuodar, G., Zakja, E., Gu, H. F., Nordman, S., Brookes, A. J., Prince, J. A., Helwig, U., Rubin, D., Hampe, J., Schreiber, S., Folsch, U. R., Doring, F., Porzio, O., Massa, O., Cunsolo, V., Hansen, T., Njolstad, P. R., Terrinoni, A., Melino, G., Federici, M., Colombo, C., Federici, G., Barbetti, F., Herder, C., Bongardt, F., Schopfer, A., Rathmann, W., Martin, S., Holle, R., Thorand, B., Wichmann, H. E., Koenig, W., Illig, T., Kora, Group, Blasiak, J., Arabski, M., Krupa, R., Wozniak, K., Dabrowski, J., Kasznicki, J., Zurawska, M., Drzewoski, J. S., Kose, H., Matsumoto, K., Wilke, B., Kerr-Bayles, L. J., Walder, K., Civitarese, A., Jowett, J., Curran, J., Elliott, K., Trevaskis, J., Bishara, N., Wanyonyi, S., Sanigorski, A. M., Zimmet, P., Blangero, J., Kissebah, A., Collier, G. R., Carlsson, E., Arner, P., Ridderstrale, M., Nitz, I., Lindner, I., Suzuki, S., Hinokio, Y., Hirai, M., Yamada, T., Yoshizumi, S., Tanizawa, Y., Matsutani, A., Ishihara, H., Takahashi, K., Katagiri, H., Oka, Y., Nam, M., Hong, S. B., Kim, H. J., Ahn, C. W., Kim, Y. S., Lee, H. C., Zeggini, E., Parkinson, J., Groves, C. J., Frayling, T. M., Hitman, G. A., Walker, M., Sampson, M., Levy, J. C., Weedon, M. N., Wiltshire, S., Owen, K. R., Halford, S., Mccarthy, M. I., Shehadeh, N., Bakri, D., Gershoni-Baruch, R., Yasuda, K., Okada, T., Sunaga, Y., Kajimoto, Y., Shibasaki, T., Kaburagi, Y., Kadowaki, T., Estalella, I., Rica, I., Vazquez, J. A., Mody, Spanish Group Of, Andrade, P., Den Ouweland, J. M. W., Maassen, J. A., Huoponen, K., Savontaus, M-L, Dimitrijevic Sreckovic, V. S., Djordjevic, P. B., Popovic, S. S., Gostiljac, D., Canovic, F., Sreckovic, B. M., Colak, E., Obrenovic, R., Milic, G., Glisic, B., Etemadi, A., Saadat, N., Azizi, F., Tsur, A., Cohen, Y., Yerushalmi, Y., Wainstein, J., Israel Diabetes Research Group (IDRG), Norberg, M., Eriksson, J. W., Lindahl, B., Andersson, C., Rolandsson, O., Stenlund, H., Weinehall, L., Lecomte, P. J., Vol, S., Caces, E., Chabrolle, C., Halimi, J-M, Nijpels, G., Dekker, J. M., Bouter, L. M., Heine, R. J., Lobner, K., Mollenhauer, U., Baumgarten, A., Com, E., Sargin, M., Karadeniz, S., Suleymanoglu, Y., Pekcanli, N., Yilmaz, T., Cicero, A. F. G., Dormi, A., Miconi, A., D Addato, S., Laghi, L., Brillante, R., Bernardi, R., Grandi, E., Gaddi, A. V., Jones, M., Lacey, L., Bergenheim, K., Yamagata, F., Yamakoshi, M., Takahashi, M., Kawazu, S., Festa, A., Hanley, A. J. G., Otvos, J. D., Goff, D. C., Wajngot, A., Cerasi, E., Baumert, J., Schneider, A., Lowel, H., Roussel, R., Muller-Brandes, C., Ballmann, M., Nahrlich, L., Thalhammer, G., Nastoll, M., Schwarz, J., Johne, U., Erfurth, M., Luddeke, H-J, Liebl, A., Kotowa, W., Maclaine, G., Evers, T., Pontiroli, A. E., Pizzocri, P., Paganelli, M., Folli, F., Lee, K., Jung, D-S, Park, M-K, Henriksen, J. E., Durck, T. T., Rasmussen, M., Weghuber, D., Roden, M., Tura, A., Pacini, G., Bischof, M., Widhalm, K., Sharp, G. W. G., Shanmugam, G., Straub, S. G., Michael, D., Chow, R., Regazzi, R., Gerona, R., Martin, T. F. J., Waselle, L., Tomas, A., Min, L., Pessin, J. E., Halban, P. A., Bjorklund, A., Ma, Z., Portwood, N., Parton, L. E., Smith, E. R., Diraison, F., Tsuboi, T., Lehtihet, M., Webb, D-L, Honkanen, R. E., Knoch, K-P, Meisterfeld, R., Bergert, H., Kolpe, M., Altkruger, A., Saeger, H-D, Solimena, M., Haspel, D., Aguilar-Bryan, L., Bryan, J., Ullrich, S., Berchtold, S., Ranta, F., Seebohm, G., Alexander, D., Wulff, P., Kuhl, D., Lang, F., Speier, S., Yang, S-B, Rose, T., Rupnik, M., Varadi, A., Mitchell, K. J., Schwappach, B., Bleck, C., Wienbergen, A., Rustenbeck, I., Vieira, E., Gylfe, E., Seissler, J., Wohlrab, U., Schmiegelt, D., Ruetter, R., Herten, M., Lechner, A., Nolan, A. L., Blacken, R. A., Habener, J. F., Gao, R., Ustinov, J., Korsgren, O., Mikkola, M., Lundin, K., Otonkoski, T., Jahr, H., Bieback, K., Kern, S., Brendel, C., Brendel, M. D., Bretzel, R. G., Taniguchi, S., Ohgawara, H., Tsuchiya, K., Tsuchiya, M., Okochi, H., Kelter, A-R, Dohrmann, C., Austen, M., Aicher, B., Maedler, K., Schumann, D. M., Iwakura, Y., Donath, M. Y., Peter, A., Opel, A., Seufert, J., Fernandez, E., Serradas, P., Martin, M. A., Plachot, C., Bailbe, D., Gangnerau, M. N., Gavete, M. L., Fajardo, S., Escriva, F., Portha, B., Alvarez, C., Lipsett, M., Jamal, A-M, Hanley, S., Castellarin, M., Rosenberg, L., Bhushan, A., Georgia, S., Calderari, S., Gangnerau, M-N, Meile, M-J, Miettinen, P. J., Palgi, J., Virkamaki, A., Ferris, W. F., Campbell, S. C., Armstrong, L., Hole, N., Lako, M., Macfarlane, W. M., Barbera, A., Altirriba, J., Nadal, B., Larsen, M. O., Gotfredsen, C. F., Holst, J. J., Reusens, B., Sparre, T., Kalbe, L., Leunda, A., Orntoft, T., Remade, C., Dasilva Xavier, G., Motakis, E., Nason, G. P., Leibiger, B., Berggren, P-O, Leibiger, I. B., Uhles, S., Moede, T., Welters, H. J., Senkel, S., Erdmann, S., Thomas, H., Morgan, N. G., Irminger, J-C, Rickenbach, K., Donath, M., Rouiller, D. G., Taylor, J. P., Jackson, D. A., Chan, S. L. F., Dezaki, K., Watanabe, M., Hosoda, H., Kangawa, K., Yada, T., Kuhnen, P., Laubner, K., Hernandez, R., Silvestre, R. A., Egido, E. M., Chatenet, D., Leprince, J., Chartrel, N., Vaudry, H., Marco, J., Zhang, F., Zhang, Q., Tengholm, A., Thore, S., Costes, S., Longuet, C., Broca, C., Baltrusch, S., Dyachok, O., Thams, P., Anwar, M. R., Capito, K., Radu, R. G., Fujimoto, S., Mukai, E., Shimono, D., Nabe, K., Shimodahira, M., Kominato, R., Aramaki, Y., Yamada, Y., Seino, Y., Giroix, M. H., Agascioglu, E., Courtois, P., Malaisse, W. J., Sener, A., Piquer, S., Barcelo-Batllori, S., Julia, M., Li, J., Li, X. J., Lou, M., Zhang, J., Zhou, Q., Zhao, G. Z., Webb, G. C., Dalal, S., Garcia, C., Saxena, P., Houk, M., Nenquin, M., Abdel-Ghany, M., Miele, C., Romano, C., Corbo, V., Maitan, M. A., Andreozzi, F., Ungaro, P., Oriente, F., Raciti, G. A., Formisano, P., Beguinot, F., Mcclenaghan, N. H., Mccluskey, J. T., Patterson, S., Efanov, A., Sewing, S., Bokvist, K., Gromada, J., Frederiksen, A. L., Juhl, C. B., Schwarts, M., Schmitz, O., Andersen, P. H., Valeri, C., Castelli, M. D., Bonfante, R., Beyan, H., Elouil, H., Khaldi, M. Z., Evangelista, S., Zeender, E., Berney, T., Schumann, D., Franklin, I., Sergeev, P., Chervonsky, A. V., Wollheim, C., Nyblom, H., Ahmed, M., Bergsten, P., Sol, E-R, Kharroubi, I., Ladriere, L., Cnop, M., Moffitt, J. H., Fielding, B., Currie, J., Staiger, K., Brandhorst, D., Winter, D., Kellerer, M., Oprescu, A. I., Naassan, A., Klimentova, T., Constantin, S. A., Tang, C., Uchino, H., Lam, L., Wheeler, M. B., Fantus, G. I., Giacca, A., Ortsater, H., Sundsten, T., Youshikawa, H., Winzell, M. S., Montrone, C., Martemucci, S., Perrini, S., Caccioppoli, C., Grassetti, D., Scipioni, A., Dotta, F., Yamamoto, N., Tsunekawa, S., Ito, Y., Oiso, Y., Miura, Y., Niki, I., Scrocchi, L. A., Ha, K. B. N., Wang, F., Chen, Y., Wu, L., Fraser, P. E., Yermen, B., Lilla, V., Kaminski, A., Mathe, Z., Dupraz, P., Zbinden, M., Filo, A., Bucher, P., Rinsch, C., Thorens, B., Pepper, M. S., Estilles, E., Sigrist, S., Rieger, L., Mandes, K., Bohbot, A., Pinget, M., Kessler, L., Parab, P. B., Katdare, M. R., Galande, S., Saha, B., Yoshida, A., Satoh, J., Homo-Dekarche, F., Coulaud, J., Durant, S., Drexhage, H. A., Mabley, J. G., Deb, A., Wallace, R., Pacher, P., Elder, R. H., Szabo, C., Schlosser, M., Mentel, R., Moya-Suri, V., Wassmuth, R., Gurtler, L., Ankelo, M., Westerlund, A., Blomberg, K., Hinkkanen, A. E., Popova, V. V., Gruzov, M. A., Afanasyeva, V. V., Kulikovskaya, A. V., Melnichenko, S. V., Mankovsky, B. N., Zak, K. P., Koczwara, K., Warncke, K., Kawasaki, E., Imagawa, A., Uchigata, Y., Kobayashi, M., Abiru, N., Yamasaki, H., Eguchi, K., Chrul, S., Polakowska, E., Heinrich, A., Walter, M., Pitocco, D., Visalli, N., Crino, A., Costantino, F., Manfrini, S., Spera, S., Suraci, C., Patera, P., Matteoli, M. C., Schiaffini, R., Ghirlanda, G., Leotta, S., Imdiab, Group, Hatziagelaki, E., Tsiavou, A., Degiannis, D., Chaidaroglou, A., Manginas, A., Koniavitou, K., Desai, M., Williams, A. J. K., Horton, V. A., Bingley, P. J., Cull, C. A., Citarrella, R., Richiusa, P., Mattina, A., Criscimanna, A., Mantione, L., Bronte, V., Pizzolanti, G., Galluzzo, A., Giordano, C., Giulietti, A., Stoffels, K., Overbergh, L., Mathieu, C., Bilgic, S., Aktas, E., Salman, F., Yillar, G., Yilmaz, M., Deniz, G., Valorani, G. M., Imdiab, G., Pozzilli, R., Weets, I., Truyen, I., Verschraegen, I., Auwera, B., Schepper, J., Dorchy, H., Lebrethon, M-C, Gaal, L., Rooy, P., Pipeleers, D. G., Gorus, F. K., Belgian Diabetes Registry (Brussels, Belgium), Shtandel, S. A., Atramentova, L. A., Karachentsev, Y. I., Kravchun, N. A., Koval, S. N., Poltorak, V. V., Levchenko, T. P., Snegurakaya, I. A., Miloslavskiy, D. K., Bojko, V. V., Resnik, L. A., Chico, A., Rojas, I., Novials, A., Bendlova, B., Vcelak, J., Vankova, M., Sramkova, D., Samalikova, P., Kvasnickova, H., Vondra, K., Petrone, A., Vania, A., Zavarella, S., Alemanno, I., Di Cola, S., Ribaudo, M. C., Leonetti, F., Angel, B., Carrasco, E., Santos, J., Albala, C., Oyarzun, A., Perez-Bravo, F., Petry, C. J., Ong, K. K., Michelmore, K., Artigas, S., Wingate, D. L., Zegher, F., Ibanez, L., Prestle, J., Adomeit, A., Hammer, E., Zieher, T., Missler, B., Appl, T., Schindler, M., Brodbeck, K., Machicao, F., Haring, H., Just, M., Fargeman, N., Knudsen, J., Quint, M., Tschank, G., Korn, M., Henriksen, E. J., Dokken, B. B., Sloniger, J. A., Dorig, J., Quarre, L., Piatkiewicz, P., Taton, J., Czech, A., Gorski, A., Jebens, E., Brennesvik, E. O., Ktori, C., Ruzzin, J., Shepherd, P. R., Jensen, J., Lakka, H-M, Rankinen, T., Leon, A. S., Skinner, J. S., Wilmore, J. H., Rao, D. C., Bouchard, C., Vendrell, J. J., Chacon, M. R., Garcia-Espana, A., Fernandez-Real, J., Gutierrez, C., Richart, C., Takeshita, Y., Shimizu, A., Hamaguchi, E., Kaneko, S., Hrebicek, J., Orel, M., Lichnovska, R., Gwozdziewiczova, S., Chlup, R., Faturos, I., Tournis, S., Fotinakis, P., Thomakos, P., Manousaki, M., Leontsini, D., Taxildaris, K., Mitrakou, A., Kim, S., Hur, K., Shim, W., Ahn, C., Cho, Y., Lim, S., Kim, K., Lee, H., Cha, B., Beregszaszi, M., Chevenne, D., Sebag, G., Kerdanet, M., Huet, F., Polak, M., Lacombe, D., Paoli, A., Levy-Marchal, C., Mokhort, T., Shishko, E., Shepelkevich, A., Benito, M., Arribas, M., Valverde, A. M., Menghini, R., Marchetti, V., Cardellini, M., Sbraccia, P., Lauro, D., Lauro, R., Ali, A. T., Penny, C., Merwe, M-T, Paiker, J. E., Psaras, G., Ekram, F., Crowther, N. J., Musri, M. M., Corominola, H., Casamitjana, R., Parrizas, M., Renstrom, F., Buren, J., Park, C., Park, Y., Lee, G., Kang, E., Kim, K-S, Sanchez-Margalet, V., Gonzalez-Yanes, C., Diaz-Troya, S., Rodriguez Fonseca, F., Mcnamara, M. R. J., Boschetti, N., Schmid, D., Spinas, G. A., Trub, T., Niessen, M., Kuhlmann, J., Neumann-Haefelin, C., Belz, U., Juretschke, H-P, Kramer, W., Herling, A. W., Markova, I., Oliyarnyk, O., Cahova, M., Manders, R. J. F., Koopman, R., Zorenc, A. H. G., Keizer, H. A., Loon, L. J. C., Straczkowski, M., Kowalska, I., Dzienis-Straczkowska, S., Nikolajuk, A., Gorska, M., Zabielski, P., Baranowski, M., Gorski, J., Tack, C. J., Haan, J., Klomp, D., Heerschap, A., Corpeleijn, E., Budzinski, R. M., Stengele, I., Schuler, M., Selzle, N., Lehmann-Lintz, T., Heckel, A., Vavrinkova, H., Meskhishvili, E., Furier, S. M., Parkes, H. A., Cooney, G. J., Alemzadeh, R., Tushaus, K. M., Nencioni, S., Giovannitti, G., Longo, V., Vries, R., Kerstens, M. N., Tol, A., Dullaart, R. P. F., Mcbride, R., Denke, M. A., Pearson, T., Battisti, W. P., Brady, W. E., Palmisano, J., Tuzova, O. V., Wahl, H. G., Hong, Q., Luz, K., Xu, G., Schmulling, R. M., Liebich, H. M., Oomen, P. H. N., Hattori, H., Smit, A. J., Scheek, L. M., Thomaseth, K., Lajoix, A-D, Gauthey, A., Dietz, S., Jahannault, C., Manteghetti, M., Petit, P., Gross, R., Quynh, N. T. T., Floren, A., Langel, U., Gedulin, B. R., Smith, P., Prickett, K. S., Tryon, M., Barnhill, S., Yeoh, T., Young, A. A., Hiles, R., Carpenter, T., Serota, D., Schafer, K., Ross, P., Nelson, D., Rebelatto, M., Ikeda, H., Nagashima, K., Tsukiyama, K., Todo, T., Trombetta, M., Boselli, L., Cali, A., Cretti, A., Monauni, T., Bifari, F., Bonora, E., Muggeo, M., Bonadonna, R. C., Gredal, C., Rosenfalck, A., Dejgaard, A., Hilsted, J., Rudovich, N. N., Rochlitz, H. J., Ritzel, R. A., Butler, A. E., Butler, P. C., Murphy, M. J., Korner, A., Csillag, J., Pinter, A., Cameron, N., Toman, M., Gray, I. P., Vielwerth, S. E., Rinnov, A., Jensen, R. B. B., Juul, A., Uitterlinden, P., Bruining, G. J., Lamberts, S. W., Rasmussen, E., Malis, C., Ekstrom, C., Arne, A., James, J. L., Thomas, P., Cavan, D. C., Owona, A. M., Ozaki, R., So, W., Tong, P., Chan, M., Wong, G., Cockram, C., Chan, J., Redemann, N. H., Gotz, B., Lahm, P., Mader, G., Tadayyon, M., Oh, Y., Schippmann, V., Kluge, R., Bornstein, S. R., Scherbaum, W. A., Joost, H-G, Bae, H. Y., Kim, S. Y., Lee, B. R., Vertigan, H., Carroll, D., Griffiths, L., Coghlan, M. P., Freeman, S., Toffolo, G., Dalla Man, C., Basu, R., Rizza, R., Cobelli, C., Bertoldo, A., Price, J., Mathis, C. A., Mason, N. S., Holt, D., Kelley, C., Mckolanis, T. M., Kelley, D. E., Whyte, M., Jackson, N., Beale, R., Treacher, D., Carroll, P., Jones, R. H., Umpleby, M., Jaquet, D., Boiko, J., Rigal, O., Czernichow, P., Qvisth, V., Hagstrom-Toft, E., Moberg, E., Bolinder, J., Sjostrand, M., Strindberg, L., Lonnroth, P., Mick, D. D., Sumarac-Dumanovic, M., Cvijovic, G. M., Kendereski, A., Pejkovic, D., Zoric, S., Casanueva, F. F., Dieguez, C. C., Singh, R. J., Basu, A., Chittilapilly, E. G., Johnson, M. C., Abdallah, B. M., Shubeska Stratrova, S., Svendsen, O. L., Dhatariya, K. K., Bigelow, M. L., Nair, K. S., Lundgren, M., Ruge, T., Myrnas, T., Gimeno, R. E., Suri, V., Li, D., Huard, C., Martine PUGNIERE, Vettore, M., Sironi, A. M., Gastaldelli, A., Mari, A., Ciociaro, D., Buzzigoli, E., Pettiti, M., Positano, V., Lombardi, M., Radziuk, J., Pye, S., Brehm, A. R., Krssak, M., Bernroider, E., Anderwald, C., Nowotny, P., Cline, G., Shulman, G. I., Kotsa, K., Papazisi, A., Spanopoulos, I., Giovos, I., Suzuki, A., Sobajima, H., Naruse, S., Kitagawa, M., Ishiguro, H., Futakuchi, S., Goto, H., Hines, G., Kennedy, I., Matthews, D., Levy, J., Radikova, Z., Koska, J., Ksinantova, L., Imrich, R., Huckova, M., Vigas, M., Wallace, T. M., Matthews, D. R., Rajala, U., Hiltunen, L., Keinanen-Kiukaanniemi, S., Noh, J-H, Kim, D-J, Choi, N-H, Lee, B-W, Chung, J-H, Min, Y-K, Lee, M-S, Kim, K-W, Lee, M-K, Byrne, C. D., Holt, H. B., Phillips, D. I. W., Wood, P. J., Darekar, A. A., Astrup, A., Gross, S., Matthies, K., Weck, M., Malinska, H., Beifort, R. S., Berria, R., Defronzo, R., Cusi, K., Gorshunska, M. Y., Karachenzev, Y. I., Lopez-Bermejo, A., Pratt, K. L., Hwa, V., Recasens, M., Broch, M., Vendrell, J., Rosenfeld, R. G., Fernandez-Real, J. M., Ricart, W., Grunnet, L., Pedersen, B. K., Franke, B., Fleming, S., Lemke, N., Laue, C., Pfeuffer, M., Lecube, A., Hernandez, C., Genesca, J., Garcia, L., Francisco, G., Simo, R., Kraml, P. J., Syrovatka, P., Brunerova, L., Smejkalova, V., Potockova, J., Andel, M., Leshchenko, Z., Poltorack, V., Krasova, N., Gladkih, A., Yang, K., Chamson, A., Thyssen, S. M., Rojo Llobet, A. M., Christoffersen, B. O., Raun, K., Fledelius, C., Svendsen, O., Vinterby, A., Golozoubova, V., Afonso, R. A., Ribeiro, R. T., Macedo, M. P., Guarino, M. P., Yang, G., Kurita, S., Misu, H., Akahori, H., Cerf, M. E., Nkomo, X. I., Muller, C. J., Du Toit, D. F., Louw, J., Wolfe-Coote, S. A., Nikishin, P., Zagayko, A., Taylor, K. D., Guo, X., Langefeld, C. D., Cur, J., Jinagouda, S., Bowden, D., Hokanson, J., Rotter, J. I., Liew, C. F., Wise, S. D., Yeo, K. P., Teng, C. H., Lee, K. O., Fisher, F. M., Trujillo, M. E., Hanif, W., Mcternan, P. G., Barnett, A. H., Scherer, P. E., Kumar, S., Kaltenbach, S., Stumvoll, M., Mlynarski, W., Andrzejewski, W., Shojaee-Moradie, F., Das, S., Stolinski, M., Jefferson, W., Cramb, R., Shahmanesh, M., Lyngso, D., Simonsen, L., Bulow, J., Meinardi, J. R., Sluiter, W. J., Wolffenbuttel, B. H. R., Bonnet, F., Guebre-Egziabher, F., Rabasa, R., Laville, M., Gosby, A. K., Maloney, C. A., Haering, H-U, Patarrao, R. S., Lautt, W. W., Correia, N. C., Santos, A. I., Leite, V., Boavida, J. M., Nanwei, T. N. W., Bobbioni-Harsch, E., Lehmann, T., Sztajzel, J., Morel, P., Huber, O., Chassot, G., Assimacopoulos-Jeannet, F., Gedulin, G., Baron, A., Hendrickx, H., Lane, J., Coverly, J., Simcox, J., Stocks, J., Brown, L., Beha, A., Juretschke, P., Gerl, M., Klebach, M., Biemer-Daub, G., Perez-Del-Pulgar, S., Zorzano, A., Heinsbroek, A. C. M., D Alessio, D., Dijk, G., Tornero, M. P., Bailey, C. J., Mack, C. M., Wilson, J. K., Parkes, D. G., Kusunoki, M., Sakakibara, F., Kato, K., Okabayashi, N., Nakamura, T., Miyata, T., Habu, S., Nakamura, R., Nakasone, Y., Yasaka, T., Ishihara, R., Morikawa, R., Otake, K., Nakaya, Y., Ruzickova, J., Rossmeisl, M., Flachs, P., Sponarova, J., Prazak, T., Matejkova, O., Kopecky, J., Gram, D. X., Liu, W., Bodvarsdottir, T., Hansen, J. B., Sturis, J., Kern, W., Hallschmid, M., Benedict, C., Schultes, B., Born, J., Fehm, H. L., Westerbacka, J., Lammi, K., Hakkinen, A-M, Rissanen, A., Yki-Jarvinen, H., Mayr, P., Mertl-Roetzer, M., Lauster, F., Pohl, M., Lerch, M., Haslbeck, M., Eriksen, J., Rahlfs, V. W., Serhiyenko, V. A., Serhiyenko, A. A., Serhiyenko, L. M., Radulian, G., Vladica, M., Panaite, C., Balas, B., Derosa, G., Dumas, A., Fiorito, A., Prieto, P. G., Cancelas, J., Loba, J., Czupryniak, L., Bialasiewicz, P., Pawlowski, M., Nowak, D., Dupuy, O., Le Berre, J. P., Bordier, L., Rousseau, C., Mayaudon, H., Bauduceau, B., Bossi, A. C., Meregalli, G., Balini, A., Berzi, D., Cremonesi, B., Cerrato, D., Rezzani, C., Tumiati, M., Han, K., Min, K., Kim, E., Ahn, K., Ahn, H., Arguelles, I., Forga, L., Izquierdo, M., Gorostiaga, E., Fuentes, C., Ibanez, J., Rivero, A., Baynes, K., Pentecost, C., Bell, J. D., Thomas, E. L., Jackson, N. C., Umpleby, A. M., Kuhl, J., Ruderman, N. B., Musi, N., Goodyear, L. J., Patti, M. E., Thorell, A., Nygren, J., Ljungkvist, O., Degerblad, M., Stahle, A., Brismar, T. B., Saha, A. K., Bavenholm, P. N., Aydemir, D., Kiran, B., Unal, M., Okumus, N., Kayserilioglu, A., Perkins, J., Salman, S., Ozer, E., Kayserilioǧlu, A., Dinccaǧ, N., Tikkanen, H., Lakka, T., Macdonald, A. L., Harrison, M., Dickinson, H., Bone, A. J., Watt, P. W., Ostergard, T., Short, K., Saltin, B., Nair, K., Di Mauro, M., Papalia, G., Battiato, R., Giuffrida, D., Boemi, G., Castellino, P., Akter, S., Akhter, A., Pervin, T., Ahmed, S., Ahmed, K. R., Saleh, F., Chaudhury, H. S., Tankova, T., Dakovska, G., Lazarova, M., Dakovska, L., Kirilov, G., Koev, D., Torgerson, J. S., Hauptman, J., Boldrin, M., Shi, Y-F, Pan, C-Y, Gao, Y., Lindgarde, F., Broom, I., Takeda, H., Oana, F., Matsuzawa, A., Hashizume, H., Akahane, S., Howlett, H. C. S., Cornes, M., Lund, S. S., Poulsen, G., Frandsen, M., Pedersen, O., Pankiv, V. I., Yngen, M., Hjemdahl, P., Wallen, N. H., Florow, D., Leyck Dieken, M. G., Kitahara, Y., Mine, T., Konya, H., Hamaguchi, T., Satani, K., Umehara, A., Ishikawa, T., Kohri, K., Hasegawa, Y., Suehiro, A., Kakishita, E., Namba, M., Wang, F. N., Liao, Z. H., Yao, B., Li, Y. B., Hu, G. L., Belcher, G., Mariz, S., Tan, M. H., Moules, I., Pfutzner, A. H., Butzer, R., Langenfeld, M., Koder, C., Cooper, M., Majali, K. Al, Adiseshiah, M., Betteridge, J., Pratipanawatr, T., Chotmongkol, R., Kanhasura, S., Pratipanawatr, W., Miyazaki, Y., Matsuda, M., Defronzo, R. A., Nagasawa, T., Kuroda, J., Dey, D., Chovatia, M., Nag, A., Pandey, B., Nag, B., Thomas, L., Krauth, M., Allgauer, S., Besenfelder, U., Dennenmoser, J., Moon, C-K, Chae, S-H, Kim, M-H, Jo, Y-Y, Shin, J-S, Ahn, S-K, Lee, H-W, Lee, S-J, Panadero Moya, A., Rodriguez, E., Gonzalo, A., Sanchez-Vilar, O., Lara, J. I., Rovira, A., Otto, C., Otto, B., Goke, B., Parhofer, K. G., Juurinen, L., Tiikkainen, M., Graner, M., Bajaj, M., Suraamornkul, S., Argon, D., Canbek, E., Schofl, C., Franzen, C., Gregg, R. E., Swaminathan, A., Frost, C., Nepal, S., Raymond, R., Mosqueda-Garcia, R., Johns, D., Gilmore, K., Perriello, G., Pampanelli, S., Di Pietro, C., Rinaldi, T., Brunetti, P., Oshinyemi, K., Garcia, S., Curtis, P., Zambanini, A., Home, P. D., Pocock, S., Dargie, H., Komajda, M., Jones, N. P., Record, Study Group, Munscher, C., Potthoff, F., Golbach, U., Weidenhammer, J., Kusterer, K., Lundershausen, R., O Neill, M. C., Goldstein, B. J., Wooddell, M. J., Strow, L. J., Waterhouse, B. R., Cobitz, A. R., Wyne, K. L., Porter, L. E., Weston, W. M., Chen, T., James, R. E., Kravitz, B. G., Pinkowski, D., Ruxer, J., Mozdzan, M., Siejka, A., Kaiser, M., Hauser, C., Jacober, S. J., Zagar, A. J., Althouse, S. K., Pinaire, J. A., Becker, R. H. A., Frick, A. D., Rave, K., Moses, R., Ways, K., Krones, R., Basir, S., Klein, C., Sawicki, P. T., Rotella, C. M., Pala, L., Dicembrini, I., Mannucci, E., Annuzzi, G., Natale, C., Bozzetto, L., Patti, L., Cipriano, P., Campaigne, B., Malone, J. K., Bai, S., Reviriego, J., Augendre-Ferrante, B., Schreiber, S. A., Schneider, K., Schweitzer, M-A, Fach, E-M, Busch, K., Karimi Anderesi, Z., Hoe, Study Group, Dunseath, G. J., Sengul, A. M., Haupt, A., Eckert, H., Schweitzer, M. A., Peiker, J., Fritsche, A., Janka, H. U., Plewe, G., Kliebe-Frisch, C., Maxeiner, S., Teng, L., Chan, C., Ernest, C. S., Skrivanek, Z., Brodows, R. G., Soon, D., Pan, C. Y., Chung, K-D, Russmann, A., Ryysy, L., Hanninen, J., Hulme, S., Kauppinen-Makelin, R., Lahdenpera, S., Lehtonen, R., Levanen, H., Nikkia, K., Tulokas, T., Virtamo, H., Vahatalo, M., Fulcher, G. R., Lavalle-Gonzalez, F., Soon, D. K. W., La Pena, A., Lim, M., Scholtz, H. E., Derezinski, T., Gerber, R. A., Hauber, A. B., Bolinder, B., Johnson, F. R., Boehm, B. O., Keiding, J., Home, P., Raastam, J., Moller, M. K., Parkner, T., Chen, J-W, Jorgensen, C., Smedegaard, J., Christiansen, J. S., Mcdougall, A., Fitch, M., Nelson, G., Mueller, U. A., Saemann, A., Ishii, H., Iburi, T., Furuya, M., Yamagami, K., Sekine, O., Yamashiro, S., Ishibashi, R., Tsujii, S., Sauriol, L., Lescrauwaet, B., Heckmann, B., Helbig, C., Franke, I., Schiel, R., Oguzhan, B., Gursoy, N., Turkish Diabetes Centers Study Group, Gutierrez, E., Garcia, P., Rokeya, B., Hossain, M. E., Ali, L., Ivanova, O. V., Gorbenko, N. I., Gladkich, A. I., Leshchenko, Z. A., Gorbenko, N., Ivanova, O., Gorbenko, K., Blase, E., Taylor, K., Nguyen, T., Su, G., Gao, H-Y, Carr, E., Wintle, M., Fineman, M., Calara, F., Han, J., Aisporna, M., Zabala, E., Fehse, F., Trautmann, M. E., Halseth, A. E., Nauck, M. A., Kendall, D. M., Riddle, M. C., Zhuang, D., Kim, D. D., Fineman, M. S., Baron, A. D., Buse, J., Henry, R., Ratner, R., Linnebjerg, H., Kothare, P., Ernest, C. Nd, Atkins, M., Trautmann, M., Bjerre Knudsen, L., Voss, P. V., Nauck, M., Hompesch, M., Filipczak, R., Le, T. T. D., Nielsen, L., Zdravkovic, M., Gumprecht, J., Deacon, C. F., Plamboeck, A., Guivarch, P-H, Dreyfus, J-F, Mathi, S., Castaigne, J-P, Drucker, D. J., Kruger, D., Burrell, T., Gloster, M., Crean, J., Herrmann, K., Maggs, D., Kolterman, O., Kovatchev, B., Cox, D. J., Mccall, A., Whitehouse, F., Kovatchev, B. P., Chapman, I., Parker, B., Doran, S., Feinle-Bisset, C., Wishart, J., Lush, C., Mcintyre, S., Deckhut, D., Horowitz, M., El-Ouaghlidi, A., Rehring, E., Holmes, D., Sallas, W. M., He, Y. L., Watson, C., Ligueros-Saylan, M., Foley, J. E., Narayanan, S., Thomas, A., Shah, D., Gopalan, B., Vakkalanka, S., Arch, J., Ryskjar, J., Krarup, T., Madsbad, S., Vilsboll, T., Ciani, S., Bardini, G., Pezzatini, A., Cappadona, A., Bodvarsdottir, T. B., Joergensen, M. S., Jensen-Holm, H. B., Kristensen, L., Kanstrup, A. B., Mckillop, A. M., Duffy, N., Lindsay, J. R., Bell, P. M., Hansen, B. S., Gronemann, S., Wilken, M., Herman, G. A., Zhao, P-L, Dietrich, B., Golor, G., Schrodter, A., Keymeulen, B., Lasseter, K. C., Kipnes, M. S., Hilliard, D., Tanen, M., Smet, M., Dyck, K., Tanaka, W., Gottesdiener, K. M., Wagner, J. A., Hoffmann, T., V Horsten, S., Demuth, H-U, Paule, S. G., Myers, M. A., Nikolovski, B., Fujiwara, H., Hosokawa, M., Fukuda, K., Nishi, Y., Fujita, Y., Yamada, K., Ueda, N., Jones-Leone, A. R., Yu, T., Barilla, D., He, Y-L, Ho, Y., Foley, J., Makrilakis, K., Panagiotakos, D. B., Dimosthenopoulos, C., Ioannidis, I., Chrysohoou, C., Pitsavos, C., Kuo, S-W, Levendal, R-A, Frost, C. L., Poonsatha, S., Jones, G., Fahey, R., Collier, G., Hoa, N. K., Norberg, A., Liepinsh, E., Phan, D. V., Thuan, N. D., Jornvall, H., Sillard, R., Ostenson, C. G., Tessari, P., Kiwanuka, E., Cristini, M., Zaramella, M., Enslen, M., Garcia-Rodenas, C., Yazawa, M., Imai, Y., Ohmura, E., Tsuchida, A., Matsuda, A., Hosaka, D., Horie, H., Ichita, M., Hisano, Y., Woodhead, S., Xu, W., Chen, X. H., Cavalot, F. L., Bonomo, K., Perna, P., Bacillo, E., Salacone, P., Gallo, M., Gaia, E., Vinik, A. I., Yu, D., Heise, M. A., Freed, M. I., Aguilera, E., Pellitero, S., Naf, S., Bendtzen, K., Nicoletti, F., Hahn, J-U, Bochnig, S., Koenig, H., Sporleder, B., Maisonneuve, P., Lowenfels, A. B., Kerner, W., Lankisch, P. G., Thai, A. C., Mohan, V., Khalid, B. A. K., Yeo, J. P., Asdiab, Study Group, Gasiorowska, A., Talar-Wojnarowska, R., Malecka-Panas, E., Schindler, K., Rieger, A., Gmeinhart, B., Schlembacher, K., Merz, P., Ludvik, B., Muller, N., Rodriguez, F. U., Aas, A-M, Seljeflot, I., Huang, C., Biswas, N., Hashimoto, N., Kamatani, Y., Suzuki, Y., Yagui, K., Saito, Y., Iwai, R., Takahashi, H., Yoshida, S., Skowronski, M., Zozulinska, D., Juszczyk, J., Wierusz-Wysocka, B., Bohles, H. J., Peterkova, V. A., Kuraeva, T. L., Scherbacheva, L. N., Andrianova, E. A., Maximova, V. P., Titovich, E. V., Danne, T., Bittner, C., Hanaire-Broutin, H., Schumicki, D-M, Souhami, E., Morrison, G., Purewal, T. S., Weston, P. J., Smahelova, A., Rusavy, Z., Koznarova, R., Loykova, V., Belobradkova, J., Devries, J. H., Retnakaran, R., Hochman, J., Melki, V., Zinman, B., Corbi, S., Costanza, F., Fioriti, E., Cappa, M., Jaron, M., Martinek, V., Piechatzek, R., Klaff, L., Prager, R., Robinson, A., Penfornis, A., Garg, S. K., Thomas, R., Selam, J. L., Sola-Gazagnes, A., Vitacolonna, E., Canonico, V., Fabietti, P., Iorio, M., Orsini Federici, M., Timi, A., Massi Benedetti, M., Sarti, E., Ashwell, S. G., Gebbie, J., Siebenhofer, A., Plank, J., Berghold, A., Horvath, K., Mrak, P., Jeitler, K. J., Pieber, T. R., Heller, S., Gottlieb, P., Paul, J., Chase, P., Menditto, L., Antuna, R., Grimaldi, A., Brun, J-M, Vialettes, B., Halimi, S., Dubroca, I., Blayo, A., Gomez-Peralta, F., Santos-Mazo, E., Payeras-Mas, F., Abreu-Padin, C., Santos-Palacios, S., Salvador-Rodriguez, J., Burge, M. R., Schroeder, E., Witthaus, E., Johnston, P., Bradley, C., Kudva, Y. C., Jenkins, G., Pons, G., Quandt, L., Gebel, J., Vogelsang, D., Smith, S., Isley, W., Russell-Jones, D., Maier, C., Mustapic, D., Schuster, E., Luger, A., Eher, R., Rubesova, I., Pelikanova, T., Skibova, J., Sanz, F. J., Ampudia-Blasco, F. J., Gabaldon, J., Catala, M., Carmena, R., Heinemann, L., Kronshage, B., Ward, K., Sass, D., Essenpreis, M., Voelkel, D., Lodwig, V., Nguyen, M., Mondok, A., Friedrich, C., Caduff, A., Totonelli, A., Longhitano, S., Agro, F., Edelman, S. V., Morrison, Z., Velazquez, F., Howard, S., Banks, R., Berger, B., Burian, P., Nilsson, K. A., Karlen, M., Rylander, E., Blonde, L., Freemantle, N., Ross, S. A., Duhot, D., Eggertsen, R., Hobbs, F. D. R., Martinez, L., Stridde, E., Skyler, J. S., Tusek, C., Stephan, J-A, Krasner, A., Landschulz, W. H., Sha, S., Bott, S., Bergenstal, R. M., Damge, C., Ubrich, N., Kaltenbacher, M-C, Maincent, P., Wutte, A., Bock, G., Balent, B., Midtgaard, A., Ronn, B. B., Pieber, T., Edgerton, D. S., Cherrington, A. D., Neal, D. W., Scott, M., Glass, D., Bowen, L. E., Wilson, W., Hobbs, C. H., Leach, C., Sivakumaran, S., Strack, T. R., Meyts, P., Aladdin, H., Palsgaard, J., Theede, A-M, Sajid, W., Hinrichsen, J., Klaproth, B., Lademann, J., Ostergaard, J., Andersen, A. S., Boss, A. H., Cheatham, W. W., Pfuetzner, A., Larbig, M., Forst, S., Abdollahnia, R., Grenningloh, M., Leatherdale, B., Bartley, E., Schwartz, S. L., Buchea, O., Shin, J., Hoss, U., Shah, R., Endo, T., Hata, S., Yamazaki, H., Hernandez Campos, S., Busciantella Ricci, N., Kaufman, F., Halvorson, M., Carpenter, S., Cooper, K., Mueller, J., Wasen, H., Brumberg, J., Rduch, K., Mertens, S., Reess, F., Renz, H., Maran, A., Sparacino, G., Pavanini, A., Corazza, S., Crepaldi, M., Poscia, A., Acosta, D., Salcedo, D., Delgado, E., Hawkins, F., Parramon, M., Mesa, J., Parhimovich, R. M., Darko, D. A., Odusanya, P. O. T., Pullen, F., Hopkins, D. F., Mukherjee, S., Child, D. F., Redkin, Y. A., Dreval, A. A., Bogomolov, V. V., Dreval, A. V., Ostgren, C. J., Grodzinsky, E., Lindstrom, K., Borgquist, L., Fegan, G., Hamliton, P., Mccrimmon, R. J., Evans, M. L., Fan, X., Ding, Y., Sherwin, R., Boomsma, F., Pramming, S., Fischer, B. M., Soydan, N., Eckhard, M., Saar, P., Kreuder, J., Linn, T., Holstein, A., Plaschke, A., Ptak, M., Egberts, E-H, El-Din, J., Kirchheiner, J., Hoashi, S., Khamis, A., Kilbane, M. T., Cannon, D. E., Gribben, A. P., Firth, R. G. R., Kinsley, B. T., Cranston, I. C., Galan, B. E., Mol, P., Wennekes, L., Due-Andersen, R., Lundkvist, J., Jonsson, L., Mukhopadhyay, B., Deans, K. A., Kesson, C. M., Jendrike, N., Buck, H., Abicht, A., Haug, C., Freckmann, G., Warren, R. E., Sommerfield, A. J., Allen, K. V., Deary, I. J., Frier, B. M., Hoi-Hansen, T., Wu, A., Holtman, V., Plaschke, A. J., Tenberken, O., Maurer, H. H., Al-Zakwani, I., Bullano, M. F., Baron, J. J., Willey, V. J., Nattrass, M., Kurtzhals, P., Colding-Jorgensen, M., Riddle, M., Massi-Benedetti, M., Murray, F., Lin, Z., Kolendorf, K., Prasek, M., Philotheou, A., Javashvili, L., Virsaladze, D., Kajaia, N., Raposo, J. F., Pratas, S., Fernandes, C., Valadas, C., Duarte, R., Gardete-Correia, L., Boavida, J., Locatelli, M., Patera, I. P., Bottazzo, G. F., Hadjidakis, D., Mylonakis, A., Raptis, A., Papaefstathiou, A., Hedman, C. A., Frystyk, J., Fridell, K., Jonsson, A., Lindstrom, T., Saito, M., Eto, M., Kaku, K., Stotzka, M., Stein, G., Prince, M. J., Kulzer, B., Scholze, A., Hermanns, N., Kubiak, T., Starostina, E. G., Shavrikova, E. P., Furuhashi, N., Hirose, T., Kuroda, M., Kimura, M., Ishizawa, M., Sarui, H., Takeda, N., Furuta, T., Drewelow, S., Lindloh, C., Paddison, C. A. M., Faimalie, M., Flett, R. A., Micheletti, S., Perelli Cippo, P., Mantovani, L. G., Su, M., Trento, M., Bajardi, M., Passera, P., Miselli, V., Tomalino, M., Borgo, E., Cavallo, F., Porta, M., Miclea, S., Bogatean, M., Hancu, N. D., Leppert, K., Rittmeier, H., Hancu, N., Mchorney, C., Myers, J., Reinecker, H., Meier, J. J., Gallwitz, B., Askenas, M., Vollmer, K., Schmidt, W. E., Kyrou, I., Souvatzoglou, E., Cseh, K., Baranyi, E., Kaszas, E., Szocs, A., Melczer, Z., Sikter, M., Szenthe, P., Hajos, P., Pogatsa, G., Winkler, G., Pardo, I. C. G., Barros-Filho, A. A., Jahan, S., Huq, F., Biswas, K. B., Chowdhury, T. A., Khan, A. R., Ritterath, C., Talai Rad, N., Siegmund, T., Heinze, T., Henrich, W., Siebert, G., Dudenhausen, J., Buhling, K., Kautzky-Willer, A., Mustafa, S., Winzer, C., Vukovich, T., Shaat, N., Ekelund, M., Lernmark, A., Ivarsson, S., Zmudzinska, M., Bronisz, A., Pufal, M., Junik, R., Beran, D. H., Toledano, Y., Giveon, S., Kahan, E., Aycheh, S., Guttman, N., Jaffe, A., Alberti, H., Boudriga, N., Nabli, M., Jaiveer, S., Jaiveer, P. K., Lee, J. D., Shaikh, S., Gopinath, A., Morrissey, J. R., Patel, V., Lenz, M., Dvoynishnikova, O. M., Mayorov, A. Y., Galstyan, G. R., Antsiferov, M. B., Dedov, I. I., Rybarczyk, M., Scalone, L., Palmer, A. J., Morgutti, M., Valentine, W. J., Renaudin, C., Roze, S., Morsanutto, A., Berto, P., Lopatriello, S., Voinovich, D., Gelisio, R., Brandie, M., Russ, W., Greiner, R. A., Rubio Terres, C., Pablos, P., Smith, I. C., Wittrup-Jensen, K., Morgan, C. L., Tsutskiridze, L., Haag, B., Delbuono, B., Silva, C., Fox, A., Padilla, V., Naraine, K., Cypryk, K., Szymczak, W., Szosland, K., Sobczak, M., Zawodniak-Szalapska, M., Lewinski, A., Schvarcz, E., Lindqvist, A., Stenninger, E., Ostlund, I., Aman, J., Lapolla, A., Dalfra, M., Di Benedetto, A., Dolci, M., Franzetti, I., Masotti, M., Napoli, A., Salietti, G., Santini, C., Tortul, C., Di Cianni, G., Popow, C., Waldhor, T., Horn, W., Biermann, E., Rihl, J., Riedl, M., Kastner, P., Kollmann, A., Pusch, W., Schreier, G., Hearnshaw, H. M., Lowe, P., Griffiths, F. E., Stapperfend, M. C., Baehring, T. U., Cosson, E., Benchimol, M., Carbillon, L., Paries, J., Lormeau, B., Valensi, P., Pharisien, I., Tourel, E., Uzan, M., Attali, J-R, Zabarovskaya, Z. V., Mulyarchik, O. V., Shepelkevich, A. P., Barsukov, A. N., Guseva, T. K., Begum, K., Haque, L., Bokor, A., Rigo, J., Garamvolgyi, Z., Pusztai, P., Somogyi, A., Hanson, U., Nystrom, L., Blohmo, G., Ekbom-Schnell, A., Ostman, J., Persson, B., Parretti, E., Cioni, R., Marzari, C., Masin, M., Scarselli, G., Mello, G., Seghieri, G., Bellis, A., Anichini, R., Alviggi, L., Franconi, F., Breschi, C. M., Dworacka, M., Wender-Ozegowska, E., Winiarska, H., Macugowska, M., Zawiejska, A., Bobkiewicz-Kozlowska, T., Pietryga, M., Brazert, J., Bousboulas, S., Politakis, P., Papadimitriou, P., Lyu, R., Yin, D. D., Green, A., Kristensen, J. K., Rodriguez-Saldana, J., Clark, C. M. Jr, Morales Teresa, M., Escorza-Dominguez, A. B., Ortiz-Gress, A. A., Monroy-Mayorga, A., Mejia-Pedraza, B. J., Seeliger, S., Kaiser, J., Muller, E., Maxion-Bergemann, S., Bergemann, R., Goertz, A., Shearer, A., Bagust, A., Schoeffski, O., Mayorov, A., Shestakova, M., Antsiferov, M., Balabolkin, M., Chugunova, L., Shamkhalova, M., Zaytseva, N., Naumenkova, I., Brevnova, N., Dedov, I., Tsibina, L., Rosak, C., Petzoldt, R., Stammer, H., Dehmel, B., Seidel, D. K., Roth, W., Fennenkotter, U., Gottschall, V., Kanatsuka, A., Lauenborg, J., Mathiesen, E., Hornnes, P., Wagner, O. F., Zajdenverg, L., Halfoun, V. L. C., Oliveira, J. E. P., Lencioni, C., Volpe, L., Chatzianagnostou, K., Cuccuru, I., Ghio, A., Pardini, E., Salvadorini, M., Saltiki, A., Korakovouni, A., Stavrianos, H., Zapanti, E., Antsaklis, A., Pithova, P., Sporna, M., Bustani, R., Todd, D. M., Lawrence, I., Guerrero, R., Vazquez, M., Amaya, M., Dios, E., Quijada, D., Garcia-Hernandez, N., Astorga, R., Gandhi, R. A., Jayawarna, C., Fernando, D. J. S., Hill, R. P., Lloyd-Mostyn, R. H., Thomson, G. A., Rewers, A., Bothner, J., Klingensmith, G., Sysoyeva, O., Karlovich, N., Rankins, D., Wellard, M., Werther, G., Northam, E., Kordonouri, O., Haberland, H., Hauschild, M., Kapellen, T., Kraft, V., Wiemann, D., Lange, K., Witte, D. R., Fuller, J. H., Eurodiab Pcs, Group, Laude, D., Dabire, H., Hadj Brahim, F., Papanas, N., Papatheodorou, K., Christakidis, D., Papazoglou, D., Giassakis, G., Piperidou, H., Monastiriotis, H., Maltezos, E., Barrett, C., Serghides, H., Tindali, H., Kelly, F., Chiheb, S., Chen, Q., Brahimi, M., Cynober, L., Delaporte, C., Scionti, L., Conti, M., Vermigli, C., Galimberti, G., Cazzetta, G., Bosi, E., Sugimoto, K., Shoji, M., Yasujima, M., Suda, T., Yagihashi, S., Mabley, J., Zsengeller, Z., Charniauskaya, T., Abatan, O. I., Kimura, I., Tsuneki, H., Hara, S., Sasaki, K., Nangle, M. R., Gibson, T. M., Yorek, M. A., Hirooka, H., Stevens, M. J., Tarhzaoui, K., Cohen-Boulakia, F., Smith, G., Lestrade, R., Behar, A., Komori, H., Oi, K., Takahashi, D., Kunitou, T., Moroi, M., Philips, J-C, Marchand, M., Geronooz, I., Scheen, A. J., Gambardella, S., Ciampittiello, G., Bracaglia, D., Cicconetti, E., Gigli, F., Verri, C., Baroni, A., Frontoni, S., Szabo, M., German, M., Farkas, L., Szentendrei, D., Maiello, M. R., Mandica, S., Morganti, R., Menzinger, G., Bernardi, L., Aso, Y., Wakabayashi, S., Takebayashi, K., Takemura, Y., Inukai, T., Kalter-Leibovici, O., Lifshitz, A., Yerushalmy, Y., Stern, E., Ogawa, K., Nanjo, K., Kawamori, R., Katayama, S., Shirai, M., Fonseca, V., Seftel, A., Denne, J., Fredlund, P., Buvat, J., Schmitt, H., Ahlen, H., Varanese, L., Lips, J., Hoekstra, J. B. L., Banga, J-D, Legros, J-J, Lufuma, M., Bouter, K. P., Fan, L. F., Lu, J. M., Zheng, Y. G., Zhang, X. Q., Spruce, M. C., Jones, C., Coppini, D. V., Lavery, L. A., Holtz-Neiderer, K., Mohler, M. J., Wendel, C. S., Nixon, B. P., Jurado, J., Bataller, F., Dorca, A., Garcia, F., Brossa, N., Barnera, T., Pou Torello, J. M., Bregovski, V. B., Karpova, I. A., Hedetoft, C., Rasmussen, A., Fabrin, J., Driver, V. R., Thoms, T. L., Jeffcoate, W. J., Monaghan, J., Game, F. L., Dalla Noce, S., Cimmino, M., Caruso, S., Manes, C., Mikoudi, K., Sossidou, E., Pigas, G., Karagianni, D., Skoutas, D., Fotiadis, S., Pruna, S., Eroshkin, I. A., Vasiljev, Y. G., Udovichenko, O. V., Udovichenko, A. E., Bondarenko, O. N., Dang, C. N., Prasad, Y. D. M., Anwar, R., Thomas, G., Malik, R., Lobmann, R., Motzkau, M., Pittasch, D., Lehnert, H., Piaggesi, A., Marsocci, A., Fanara, M. G., Rizzo, L., Palumbo, F., Campi, F., Tedeschi, A., Scatena, A., Goretti, C., Baicchi, U., Chipchase, S., Treece, K., Pound, N., Hill, N. R., Cyganek, K., Mirkiewicz-Sieradzka, B., Malecki, M., Wolkow, P., Skupien, J., Naskalska, A., Sieradzki, J., Tapp, R. J., Tonkin, A. M., Harper, A., Mccarty, D. J., Soderberg, S., Taylor, H. R., Chitson, P., Alberti, G. K. M., Sheetz, M. J., Aiello, L. P., Davis, M. D., Milton, R. C., Arora, V., Hu, K., Girach, A., Vignati, L., Tyrberg, M., Melander, A., Lindblad, U., Giannarelli, R., Coppelli, A., Sartini, M., Aragona, M., Fletcher, E. L., Ninkovic, S., Foster, L. E., Jones, D., Gooyer, T., Stitt, A., Vingrys, A. J., Wilkinson-Berka, J. L., Lewandowska, A. B., Randeva, H. S., Komorowski, J., Lewandowski, K. C., Jurowski, P., Sankar, S., Gos, R., Kowluru, R. A., Odenbach, S., Shinn, S., Oh, Y-S, Kim, J., Agardh, C-D, Hultberg, B., Agardh, E., Segura, R. M., Fonollosa, A., Berrone, E., Beltramo, E., Solimine, C., Ubertalli, A., Islam, N., Esteve, E., Fernandez, M., Recas, I., Mauri, S., Biarnes, F., Junca, E., Fernadez-Real, J., Rossner, S., Stenlof, K., Levy, B., Perry, B., Fitchet, M., Chrysos, G., Kamaratos, A., Lepeniotis, G., Kokkoris, S., Varytimiadis, K., Stasini, F., Mikros, S., Gianneli, D., Tryfinopoulou, K., Melidonis, A., Nikolopoulou, C., Harley, K., Ryder, R., De, P, Vannieuwenhoven, F. A., Rossing, K., Oliver, N., Goldschmeding, R., Jacobsen, P. K., Tan, F., Liew, S., Mukherjee, J. J., Lim, P., Frojdo, S., Sjolind, L., Parkkonen, M., Makinen, V., Tikellis, C., Nieuwenhoven, F. A. V., Macisaac, R. J., Tsalamandris, C., Mcneil, K. J., Panaiotopoulos, S., Smith, T. J., Ho, M., Matthews, P. G., Jerums, G., Hut, H., Den Meiracker, A. H., Nakhjavani, M., Behjati, J., Esteghamati, A., Esfahanian, F., Aghamohamadzadeh, N., Abbasi, M., Kohnert, K-D, Zander, E., Krabbe, S., Stehouwer, C. D., Schalkwijk, C. G., Saraheimo, M. T., Krarup Hansen, T., Teppo, A-M, Ebeling, P., Hansen, B. V., Abdella, N. A., Mojiminiyi, O. A., Al Dahi, W. A., Al Mohammedi, H., Al Jebely, S., Neugebauer-Baba, S., Baba, T., Ohashi, H., Nakajima, S., Hesselmann, C., Watanabe, T., Nargis, M., Zaid, R. B., Voronko, O. E., Shestakova, M. V., Shamkhalova, M. S., Tchugunova, L. A., Vikulova, O. K., Nosikov, V. V., Liu, L., Zheng, T., Li, M., Zhang, R., Xiang, K., Hadjadj, S., Jeunemaitre, X., Vervoort, G., Veldman, B., Berden, J., Wetzels, J., Singh, B. M., Holland, M. R., Baskar, V., Oh, J., Seo, J., Choi, K., Baik, S., Choi, D., Kim, N., Matsumoto, S., Suetsugu, M., Matsutomo, R., Pisarczyk-Wiza, D., Banaszak, A., Wysocki, H., Usui, H., Shikata, K., Okada, S., Ogawa, D., Yozai, K., Kido, Y., Nagase, R., Ohga, S., Tone, A., Sasaki, M., Wada, J., Unno, Y., Horiuchi, S., Mclennan, S. V., Kamarinos, M., Kelly, D., Waltham, M., Dy, V., Yue, D., Langham, R., Gilbert, R., Zdychova, J., Komers, R., Cresci, B., Giannini, S., Manuelli, C., Giunti, S., Pinach, S., Ianni Palarchio, A., Arnaldi, L., Vittone, F., Camussi, G., Cavallo Perin, P., Gruden, G., Marshall, S. M., Jones, S. E., White, K. E., Brizzi, M., Dentelli, P., Rosso, A., Calvi, C., Gambino, R., Cassader, M., Salvidio, G., Deferrari, G., Pegoraro, L., Pagano, G., Cavallo-Perin, P., Oates, R., Ellery, C., Beebe, D., Coutcher, J., Qian, Y-Z, Lowe, V., Appleton, T., Raunig, D., O Neil, S., Mylari, B., Amazonas, R. B., Fujita, A., Doi, A., Matsuno, S., Okamoto, K., Matsumoto, E., Furuta, H., Nishi, M., Tsuno, T., Taniguchi, H., Bessho, H., Wasen, E., Isoaho, R., Mattila, K., Vahlberg, T., Kivela, S-L, Irjala, K., Rigalleau, V., Lasseur, C., Perlemoine, C., Barthes, N., Raffaitin, C., Chauveau, P., Combe, C., Baillet-Blanco, L., Beauvieux, M-C, Gin, H., Heinrich, S., Steiner, T., Ott, U., Holdass, H., Fellstrom, B., Jardine, A., Staffler, B., Logan, J. O., Gimpelewicz, C., Stanciu, C. C., Pena, C. M., Serafinceanu, C. C., Gonzalez-Posada, J. M., Hernandez, D., Perez-Tamajo, L., Lo, A. J., Herna Alarco, M., Meneses, M., Barsotti, M., Rizzo, G., Schmauss, S., Havrdova, T., Saudek, F., Boucek, P., Adamec, M., Invitti, C., Gilardini, L., Parati, G., Mazzilli, G., Pontiggia, B., Sartorio, A., Lutgers, H. L., Groenier, K. H., Zasadzinska, G., Saryusz-Wolska, M., Temelkova-Kurktschiev, T. S., Kurktschiev, D. P., Majdrakova, I., Varbanova, T., Todorova, B., Bajo-Martinez, A., Bernal, E., Sanchez, O., Ugalde-Canitrot, A., Sanchez-Largo, E., Coca-Robinot, D., Fabregate, R., Calbacho, M., Marquez, J., Saban-Ruiz, J., Penesova, A., Cizmarova, E., Blazicek, P., Jongh, R. T., Serne, E. H., Ijzerman, R. G., Vries, G., Stehouwer, C. D. A., Poulsen, P. L., Andersen, N. H., Knudsen, S. T., Helleberg, K., Mogensen, C. E., Walus, M., Idzior-Walus, B., Sztefko, K., Cieslik, G., Fedak, D., Wozniakiewicz, E., Lin, S. D., Guo, M. Y., Lin, C. J., Liu, X. C., Francisco, M-M J., Rodriguez-Rosas, H., Peiro-Martinez, I., Macias-Batista, A., Harte, A. L., Rodriguez-Cuenca, S., Valsamakis, G., Chetty, R., Anderson, L. A., Roca, P., Matyka, K., Lasalle, J., Hershon, K., Berman, L., Gibson, E., Gillen, D., Maroni, J., Simmons, D., Hiukka, A., Forder, P., Leinonen, E., Hilden, H., Fruchart, J., Fruchart, J-C, Keech, A., Farnier, M., Freeman, M., Macdonell, G., Perevozskaya, I., Mitchel, Y., Gumbiner, B., Didangelos, T. P., Athyros, V. G., Mikhailidis, D. P., Papageorgiou, A. A., Bouloukos, V. I., Pehlivanidis, A. N., Symeonidis, A. N., Elisaf, M., Mckenney, J., Insull, W. Jr, Lewin, A., Maccubbin, D., Lee, M., Kush, D., Schuster, H., Barter, P. J., Stender, S., Cheung, R. C., Bonnet, J., Morrell, J. M., Watkins, C., Kallend, D., Stalenhoef, A. F. H., Ballantyne, C. M., Murin, J., Tonstad, S., Rose, H., Wilpshaar, W., Jenkins, A., Karschimkus, C., Dragicevic, G., Rowley, K., Wolthers, T., Best, J. D., Voet, B., Murdoch, S. J., Marcovina, S. M., Chen, H. C., Brunzell, J. D., Caparevic, Z. V., Kostic, N. D., Ilic, S. M., Sartore, G., Piarulli, F., Cantaro, S., Reitano, R., Fiore, C., Marin, R., Bassan, S., Manzato, E., Fedele, D., Solini, A., Santini, E., Thornalley, P. J., Babaei-Jadidi, R., Karachalias, N., Kupich, C., Ahmed, N., Fowler, A. E., Baker, A. R., Starczynski, J., O Hare, P., Szepietowska, B., Szelachowska, M., Puch, U., Glebocka, A., Quinn, D. W., Da Silva, N. F., Mcternan, C. L., Bonser, R. S., Mcternan, P., Dimitriou, K., Apostolou, O., Kontela, E., Devangelio, E., Gould, E. M., Serri, O., Roussin, A., Buithieu, J., Mamputu, J-C, Renier, G., Giordanetti, S., Amici, E., Poggi, G., Turpini, C., Fratino, P., Garzaniti, A., Yin, D., Banu, I., Roman, G., Negrean, M., Bala, C. G., Nita, C., Kistorp, C., Gustafsson, F., Chong, A., Lip, G., Galatius, S., Shearer, A. T., Ari, N., Sahilli, M., Ceylan-Isik, A., Ozansoy, G., Karasu-Yilmaz, C., Matteucci, E., Rosada, J., Pallini, M., Evangelista, I., Cassetti, G., Giusti, C., Giampietro, O., Capaldo, B., Galderisi, M., Cicala, S., Turco, A., Imbroinise, A., Nosso, G., D Errico, A., Divitiis, O., Klimontov, V. V., Korolyova, E. A., Jeltova, L. I., Bondar, I. A., Tarkun, I., Arslan, B., Canturk, Z., Tarkun, P., Agacdiken, A., Komsuoglu, B., Meneveau, N., Pierre-Justin, E., Alsayed, M., Sabbah, R., Paulin, S., Marcu, S., Tauveron, I., Zimmermann, C., Schiele, F., Seronde, M-E, Vautrin, P., Lusson, J-R, Thieblot, P., Bernard, Y., Mistry, A., Pye, M. P., Peovska, I., Maksimovic Pavlovic, J., Vavlukis, M., Pop Gorceva, D., Bosevski, M., Scognamiglio, R., Negut, C., Kreutzenberg, S., Madonna, R., Caterina, R., Willerson, J. T., Geng, Y-J, Vahsen, S., Ledwig, D., Ramrath, S., Frantz, S., Schmidt, I., Calvillo, L., Dienesch, C., Elbing, I., Bischoff, H., Ertl, G., Bauersachs, J., Davydov, A. L., Mkrtum Yan, A. M., Baranova, L. Y., Ikeda, Y., Suehiro, T., Osaki, F., Ota, K., Arii, K., Kumon, Y., Hashimoto, K., Doney, A. S. F., Fischer, B., Morris, A. D., Palmer, C. N. A., Ahn, Y-M, Lee, B-C, Kim, S-I, Byun, S-H, Ahn, S-Y, Doo, H-K, Pagnin, E., Calo, L. A., Fadini, G., Kubaszek, A., Chai, S., Chai, Q., Rasmussen, L., Ledet, T., Wogensen, L., Lengyel, C., Varro, A., Virag, L., Magyar, J., Biro, T., Jost, N., Skoumal, R., Nanasi, P., Toth, M., Horkay, F., Papp, J. G., Zacharopoulou, O., Athanaselis, S., Tsokos, N., Doupis, J., Psallas, M., Cokkinos, D., Pavlatos, S., Liatis, S., Akhobadze, T., Dzneladze, L., Samarguliani, I., Taskiran, M., Rasmussen, V., Rasmussen, B., Jensen, G. B., Fisher, A. A., Petrovsky, N., Davis, M. W., Srikusalanukul, W., Budge, M. M., Trifunovic-Zamaklar, D. D., Zivkovic, M., Jelic, V., Vukomanovic, G., Ristic, A. D., Seferovic, P. M., Costa, J. V., Duarte, S., Manley, S. E., Sailesh, S., Venkataraman, A., Haider, Y., Groza, I., Oprean, M., Ardelean, A., Morosanu, A., Darkow, T., Vanderplas, A., Mamas, M. A., Mcelduff, P., Burns, J., Edwards, R., Fitchet, A., Young, R. J., Gibson, J. M., New, J. P., Lichiardopol, R., Niculescu, N., Totora, A., Pencea, C., Tomescu, I., Cinteza, M., Manicardi, V., Coscelli, C., Navazio, A., Catellani, E., Michelini, M., Dall Asta, D., Guberti, A., Piazza, A., Gasparini, E., Pantaleoni, M., Guiducci, U., Manari, A., Sejil, S., Janand-Delenne, B., Avierinos, J-F, Habib, G., Labastie, N., Vague, P., Lassmann-Vague, V., Luzniak, P., Wojciechowska Luzniak, A., Zairis, M., Lyras, A., Patsourakos, N., Tsirimbis, V., Foussas, S., Lupon, J., Urrutia, A., Herreros, J., Gonzalez, B., Coll, R., Altimir, S., Prats, M., Valle, V., Abreu-Padi, C., Rabago, G., Ivanova, L. A., Brasacchio, D., Calkin, A., Jandeleit-Dahm, K. A., Harno, E., Keenan, A. K., Li, H. L., Yu, Y. R., Lu, Z. M., Zhang, X. E., Ke, L., Liu, H., Zhang, X. X., Jeong, I-K, Chae, M-K, Choi, M-H, Yoo, H-J, Kim, C. D., Yun, M. R., Na, M. A., Kang, Y. H., Kong, O. N., Son, S. M., Kim, I. J., Kim, Y. K., Tanaka, N., Hosoi, M., Matsuyama, Y., Fukumoto, M., Yamakita, T., Yoshioka, K., Ishii, T., Sato, T., Fujii, S., Aoki, T., Shibata, T., Mizutani, N., Suzuki, J-Y, Fowelin, J. H. R., Samuelsson, P., Brandrup-Wogsen, G., Okumura, K., Tokmakova, A. Y., Staroverova, D. N., Antcieferov, M. B., Shutichina, I. V., Kuntchevich, G. I., Vriesendorp, T. M., Morelis, Q. J., Legemate, D. A., Schaper, F., Mainas, E. I., Gkioulmpasanis, I., Panagiotou, I., Vassilikos, G., Skorda, L., Sidira, M., Christoforidou, M., Alaveras, A., Artikis, V., Evdemon, E., Lechleitner, M., Koch, T., Ebenbichler, C., Sturm, W., Moretti, L., Moruzzo, D., Boldrini, E., Pandolfo, C., Kameyama, M., Iwasa, R., Cho, M-H, Nam, J-Y, Kim, C-S, Kim, D-M, Ahn, C-W, Cha, B-S, Lim, S-K, Kim, K-R, Lee, H-C, Huh, K-B, Kaplar, M., Paragh, G., Erdei, A., Csongradi, E., Garai, I., Varga, J., Galuska, L., Udvardy, M., Higa, M., Kaneko, Y., Hiroi, N., Koziarska, D., Nowacki, P., Majkowska, L., Wojciechowska-Luzniak, A., Tushuizen, M. E., Nieuwland, R., Snoeck, D. P., Sturk, A., Diamant, M., Aguiar, L. G. K., Bahia, L., Villela, N., Laflor, C., Conde, C., Bottino, D., Dorigo, D., Bouskela, E., Pu, S., Yu, H. L., Luo, Z. T., Lam, K. S. L., Dan, Q., Xu, A., Shen, J., Cheng, K., Xu, J. Y. U., Thamer, C., Stefan, N., Haap, M., Heller, E., Tschritter, O., Prado, A., Ortiz, A., Ybarra, J., Gich, I., Pou, J. M., Ehren, M., Meyer, M. F., Roggenland, D., Reinsen, B., Klein, H. H., Rittig, K., Stock, J., Kocher, B., Balletshofer, B., Lee, J., Shon, H. S., Chung, D. S., Nakatani, Y., Matsuhisa, M., Kaneto, H., Hatazaki, M., Yoshiuchi, K., Katakami, N., Kawamori, D., Ohtoshi, K., Sakamoto, K., Matsuoka, T-A, Ozawa, K., Ogawa, S., Hori, M., Yamasaki, Y., Zitouni, K., Harry, D., Nourooz-Zadeh, J., Betteridge, J. D., Earle, K. A., Rasmussen, L. M., Olesen, P., Franco, L., Corvaja, C., Semplicini, A., Rosen, P., Lee, I-K, Kim, M-J, Park, K-G, Jung, E-D, Shin, D-W, Jo, S-R, Obuobie, K., Prakash, P. K., Hanna, F. W., Evans, M., Lazarus, J., Varadhan, L., Gurushankar, J., James, D., Sheikh, S., Gaede, P., Li, H., Zou, D., Lee, S. J., Choi, M. G., Kim, D. S., Kim, T. W., Vilarrasa, N., Perez-Maraver, M., Mena, E., Perez, D., Setti, G., Buckingham, R., Urbancic, V., Stefanovska, A., Bernjak, A., Azman-Juvan, K., Kocijancic, A., Glowania, A., Filters, T. S., Fosmark, D. S., Torjesen, P. A., Kilhovd, B., Berg, T. J., Sandvik, L., Hanssen, K. F., Mentink, C. J. A., Kilhovd, B. K., Kuchmerovska, T. M., Shymanskyy, I. O., Donchenko, G. V., Stepanenko, S. P., Klimenko, A. P., Park, J., Maingrette, F., Deng, H. C., Lindenmair, A., Waldhausl, W. K., Freudenthaler, A., Baumgartner-Parzer, S. M., Nizheradze, K., Khoruzhenko, A., Tronko, N., Sheu, W. H. H., Ou, H-C, Shen, H-M, Lin, T-M, Wu, H-S, Yang, C-H, Mogylnytska, L., Mankovsky, B., Schmoelzer, I., Davies, J. I., Band, M., Morris, A., Struthers, A. D., Prazny, M., Skrha, J., Kasalova, Z., Neelotpol, S., Jahan, P., Kauschke, S. G., Harrop, C. A., Schafer, A., Widder, J., Eigenthaler, M., Walter, U., Uchimura, I., Ikebukuro, M., Kaibara, M., Hirata, M., Helal, R., Pervin, F., Khan, A. K. A., Yang, X., Jansson, P-A, Nagaev, I., Jack, M. M., Carvalho, E., Sunnerhagen, K. Stibrant, Cam, M. C., Cushman, S. W., Smith, U., Creely, S. J., Farmer, J., Creely, S., Gustafson, B., Kusminski, C. M., Krusinova, E., Wohl, P., Klementova, M., Lanska, V., Mcdougall, C., Thomas, S. J., Kelly, I., Abbas, Z. G., Lutale, J. K., Archibald, L. K., Karunajeewa, H., Stingemore, N., Stuccio, G., Mcgechie, D., Muller, L. M. A., Hak, E., Goudzwaard, W. L., Montorsi, F., Homering, M., Sprenger, K., Goldstein, I., Asnaghi, V., Ferrari, G., Rastaldi, M., Gabellini, D., Antonio, G., Maestroni, A., Ruggieri, D., Luzi, L., Piemonti, L., Zerbini, G., Anafaroglu, I., Tutuncu, N. B., Sultana, M., Siddiqua, N., Iwasaki, T., Nakajima, A., Yoneda, M., Mukasa, K., Tanaka, S., and Sekihara, H.
19. 40(th) EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004
- Author
-
S. Artigas, A V Dreval, Mark I. McCarthy, C Watson, Peter H. Bennett, M Quint, Y Ikeda, E Alpert, F Schiele, H Sekihara, Erik Gylfe, P Lowe, J Kuhlmann, Alain Golay, V Longo, Shahidul Alam Khan Akm., L G Mantovani, M Zawodniak-Szalapska, G Winkler, T Harrity, L Virág, U Johne, Kuo S-W., Linda C Tapsell, J Rodriguez, Michel Komajda, K Kankova, Carole A. Cull, M Sporna, E Estilles, U Ribel, M C Spruce, E Buzzigoli, T Prazak, J K McLaughlin, M K Lingohr, M Lim, F Calara, A Siebenhofer, G Meregalli, Roberto Anichini, A D Baron, R Kurashvili, P C Butler, G I Fantus, T. E. De Gooyer, Park Y-M., R. Walther, S Heinrich, Agnieszka Zawiejska, S Mukherjee, Nikolaos Papanas, G Wong, Ian D. Caterson, David M. Maahs, Shuichi Kaneko, Alexandra E. Butler, Francisco Javier Ampudia-Blasco, O N Kong, Attali J-R., C A Hedman, K Oshinyemi, Nicolle Müller, I C Cranston, N Okumus, M V Vlaiculescu, Balasubramanian Ravikumar, W W Cheatham, K Mukasa, K B Biswas, Annunziata Lapolla, Phil McEwan, G Mader, Gilles Chassot, Dragi Anevski, Werner A. Scherbaum, M Donath, C Hesselmann, R A Gandhi, David E. Moller, Ezio Bonifacio, C Garcia, V Ifandi, P Hornnes, Nieuwenhoven Fav., C Puech, S Pérez-Del-Pulgar, Kim S-R., G Hines, C Rubio Terrés, Michael Gaster, N. Hosszufalusi, A Scholze, Andrew A. Young, Stavros Liatis, F Hariri, S Tan, Paul Valensi, Allan E. Karlsen, J Kim, E. Moberg, J Kaiser, L Berman, G Nelson, A Altkrüger, P Kothare, D B Cook, S Doran, G. van Dijk, Shahnaz Shahinfar, Kim C-S., P Stahl, M Manousaki, S Sigrist, S K Lim, M. P. Stern, A Guberti, C Rezzani, J McKenney, Karl Thomaseth, Sofia Carlsson, M Julia, R Brillante, I Rubesova, T Darkow, E Matsumoto, Wendy M. Macfarlane, M Di Martino, G Bardini, Rossella Menghini, D Duhot, E Farcasiu, Annalisa Natalicchio, I Lindner, J Buvat, Christian L. Brand, Harry Dorchy, Iwona Pietrzak, Z T Luo, P Home, M Ekelund, Jesper Gromada, Kristine Færch, F Piarulli, H Kim, R Mentel, Zsuzsanna K. Zsengellér, Dullaart Rpf., Anton Luger, Thomas A. Pearson, V Manicardi, P Rösen, Feng Y-M., R Morganti, Lars Hansen, Demuth H-U., Haruo Kasai, A Shostak, Rudi Steffensen, G Taylor, Markolf Hanefeld, C Santini, E Hamaguchi, Roberto Miccoli, F Storms, M Cooper, Y Lee, Allison E. Aiello, P Smith, T Suehiro, K Treece, M Waluś, Timothy A Welborn, Simone Baltrusch, E Kontela, S Chai, J Crean, H Yokoyama, Johan G. Eriksson, Rafael Hernández Hernández, J Rodríguez-Saldaña, M P Tornero, G Formoso, D. Lovell, E Bingham, A Mylonakis, M Manteghetti, D Fedele, Antonio Martín-Duce, Ralph A. DeFronzo, D Salcedo, Kurt Højlund, Antonio Petrone, Sheu Whh., C Gutierrez, Flavia Pricci, S Kurita, Z G Abbas, M M Benedetti, Philippe A. Halban, Daniel J. Cox, O Ljungkvist, Justine Davies, J Palsgaard, Lars Sjöström, E Bosi, L Janin-Manificat, W. F. Kelly, M. Fernandez, E Colak, O V Mulyarchik, B Kronshage, F Lang, M Erfurth, Takashi Kadowaki, N Jendrike, U Walter, J Wishart, Y. Neye, D Kim, N Furuhashi, M Barsotti, D Florow, L Ke, L Borgquist, N C Jackson, Ffolliott M. Fisher, V Baskar, K Yoshioka, Bryan A. Wolf, G Chabrier, R Skoumal, Livio Luzi, H Kose, I Pharisien, B. Klein, H Winiarska, M C Johnson, L Griffiths, Nonna Kravchun, C Combe, Baptist Gallwitz, J Zdychova, L Skorda, Jorma Ilonen, W Gao, I N Steen, A Terrinoni, P D Ambery, W Kern, C M Kusminski, Cho M-H., Paolo Pozzilli, Louise G. Grunnet, E Schönle, David R Matthews, Robert W. Taylor, Y Cohen, Kim H-S., M P Eccles, N B Tutuncu, D McDowell, Richard M. Bergenstal, K Takamatsu, T Steiner, Jaan Palgi, Valdemar Grill, N Niculescu, G Federici, S Lehto, P. M. McKeigue, M Barone, Michael E. Trautmann, S Smirnov, J Mannion, M Eto, C Rousseau, M Conti, C S Ernest, Antonio Ceriello, D H Schweitzer, Jung E-D., Andreas Festa, Avijit Lahiri, A Shepelkevich, A Murro, A Kollmann, Jonathan R.S. Arch, R Landgraf, Son H-Y., I Engelsberger, E Agardh, S Rodríguez-Mulero, P J Kraml, K Lee, D. F. Du Toit, E Kim, G Fadini, Williams Ajk., Philip Home, M B Antcieferov, C Perlemoine, D Perrea, Song X-L., D Ruggieri, Krister Bokvist, Heidi Sørensen, Bilbao, G Yoshino, J P Taylor, Shen H-M., S M Furier, R Urquhart, J Wohlgelernter, Jianping Weng, T. Baba, Q Hong, C Silva, Castaigne J-P., M Felaco, X X Zhang, M Jaroň, Milla Rosengård-Bärlund, J G Papp, Toshio Miyata, Lervang H-H., Park M-K., I Kinalska, A Long, Oomen Phn., N Kogawa, Ippolita Patrizia Patera, S. Karadeniz, Dinesh Selvarajah, D S Chung, A Wensaas, Richard Imrich, M Recasens, J Ruxer, O Buchea, E Wilpart, S P Stepanenko, Le Ttd., H Ohgawara, Mariaconsuelo Valentini, A Mondok, M Peltonen, Marianne O. Larsen, K Chatzianagnostou, Agneta Ståhle, A L Ferrari, L Bordier, F Maingrette, A Matsuda, G Vukomanovic, Jakob D. Wikstrom, T Yamakita, E Gorostiaga, J Jin, B Gopalan, Heinz Drexel, S Hewitt, Rury R. Holman, C Dieterle, T L Ruchti, N Asatiani, M Sidira, A Iezzi, A J Sommerfield, D Châtenet, M L Olsen, R Bergemann, C Koehler, T L Kuraeva, B Balas, Christian Berne, E Santos-Mazo, G Smith, A Siejka, R Kožnarová, A Mattina, S Sheikh, A Adomeit, M Rasmussen, J. Fagerudd, N Busciantella Ricci, Nuria Vilarrasa, E Hammar, T L Thoms, L Aydın, Ron G. Rosenfeld, A Nikolajuk, R Gos, C L Morgan, H L Yu, D Dheelchand, S Ramrath, N Boudriga, Jerome I. Rotter, C Jahannault, W M Weston, Folke Lindgärde, M Hertlova, D Knight, A Monroy-Mayorga, E Pardini, A Chamson-Reig, B Franke, Janie McCluskey, Joseph Bryan, C Nikolopoulou, Christie M. Ballantyne, Fausto Santeusanio, L Pegoraro, M Lee, A Klimenko, S Jaiveer, K. Pettersson-Fernholm, Michael A. Nauck, A Ekbom-Schnell, G Deferrari, Riccardo Schiaffini, S. Pampanelli, Khan Aka., David Hopkins, Maija Wessman, M Kamarinos, Noh J-H., O Ebisui, K McCarroll, Jeppe Sturis, Peter Nowotny, N Gorbenko, Åke Sjöholm, David G. Maggs, A E Halseth, B Cresci, A A Ortiz-Gress, A Korakovouni, O Matejkova, C E Mogensen, C J Lin, Ramon Gomis, H Seaman, C Granier, Yang C-H., F Assah, O Sanchez, Fausto Machicao, Peter G. Morris, Alberto Ortiz, A Giardinelli, D Bracaglia, A Gonzalo, S Pavlatos, Andreas Lechner, F Canovic, L Sjolind, Allan Vaag, Birgitte Bruun Nielsen, David A. Ziegler, Vito Lampasona, R Gershoni-Baruch, A. Dei Cas, H Renz, E Mena, Matthew Waltham, Kim D-M., H Levanen, D D Mick, Valentina Alexandrovna Peterkova, E Meskhishvili, Sarah Nutland, R Bustani, John R. Lindsay, M Christoforidou, A Abicht, E Harno, K Cyganek, A Fitchet, S Neelotpol, P Nikishin, P Serradas, J Hinrichsen, M Halvorson, M Chovatia, B Voet, Jinny Willis, E Parretti, M Haslbeck, M Wellard, L Teng, Julio Wainstein, J S Fischer, K. Lalic, D Roggenland, I Gich, R Anwar, Maurizio Cassader, D Serota, X J Li, R J Schotzinger, Vilmundur Gudnason, Björn Zethelius, S A Wootton, W Andrzejewski, R Rezsohazy, R Gao, T Klimentova, T Mazurek, I Bruckner, C Dohrmann, R E James, G daSilva Xavier, Kim S-Y., A Dorca, Stuart J. Pocock, Terri J. Allen, I Giovos, P B Parab, N H Andersen, P Fotinakis, Miriam Cnop, H Lee, Norbert Tennagels, Omorodola I. Abatan, F Ailett, I. Lager, D Manzella, H Hut, Larry A. Distiller, G Lip, Lim S-K., Rong Zhang, T Tsuno, Steen Knudsen, M. Bajardi, Manuel Benito, Dai Sugimoto, Melvin J. Prince, D W Dunstan, D Rankins, K A Majali, G Ozansoy, Isabella Russo, S Uçak, G Annuzzi, R Talar-Wojnarowska, K Lange, S Neugebauer-Baba, Campbell H. Thompson, Eric Renard, P. D. Mountjoy, Z Morrison, Elizabeth A. Davis, Franco Cavallo, C Corvaja, R Antuña, Craig John Currie, H Linnebjerg, He Y-L., A J Palmer, Mariola R. Chacón, H Malinska, M. Jones, R Lichnovská, K Mandes, Paolo Tessari, T Mokhort, A Laina, H. L. Y. Chan, I Schmidt, R Banks, Richard G. IJzerman, L Ksinantova, G Setti, H Vaudry, A Gallo, V Spallone, Chen J-W., Thomas Danne, A Chong, M Hallschmid, S Aczel, S Hulme, N Islam, M Hosoi, P M Ternan, P Di Bartolo, N Bishara, T Shibasaki, Martin A. Osterhoff, Im S-S., M Jecht, T Hamaguchi, S Mattera, K Ways, Elizabeth Northam, U Rajala, Reinhard W. Holl, L Yang, S Panaiotopoulos, K Horvath, R Kluge, Thora B. Bodvarsdottir, Y Dong, Irene Alemanno, C McDougall, Reimar W. Thomsen, M Campbell, W Rabl, John Öhrvik, Yuichiro Yamada, Paola Ungaro, W Benzer, Mike Sampson, Roberto Trevisan, R G Radu, Aas A-M., P E Lobo, Ricardo Scott, S M Son, Josephine M. Forbes, T A Hillier, K L Wyne, Louis L. Nguyen, J Farmer, M H Tan, Kwon H-S., J Yang, L Sandvik, Franco Folli, A K Jenum, M Nguyen, W Pratipanawatr, A L Frederiksen, Rebecca Smith, Lee H-J., A Schäfer, C Manuelli, G S Denver, T Vukovich, B Maceira, K Matsumoto, K. Chokkalingam, Nurcan Üçeyler, P Modi, Timothy M. Morgan, S Mertens, B M Singh, Michaela Riedl, K Iso, C Cucurullo, G. F. Bottazzo, M Calvani, K Hur, J Wetzels, Kazuhiro Takahashi, Y Aso, H Stammer, M G Masding, Fitsum Guebre-Egziabher, J L González-Sánchez, L Armstrong, Alberto Maran, Peter G.F. Swift, S S Popovic, J Starczynski, E Vitacolonna, Luigi Laviola, R W Gelling, Marina Cardellini, D Barilla, Rosa de Diego Martínez, W H Landschulz, Anne Mette Rosenfalck, R K Wong, Kevin E. Schneider, K Peros, Giuseppe Nanni, F Zhang, I Rákóczi, T Iburi, M Nakhjavani, X Q Zhang, S Tournis, Per Lav Madsen, Graham A. Hitman, A. Tura, K Laubner, N D Kostic, Lawrence M. Dolan, R. Sinha Roy, J A Wagner, J. Tuomilehto, J Hauptman, M Abdel-Ghany, D Lacombe, Toralph Ruge, Johannes A Maassen, Triantafyllos Didangelos, K Sasaki, I Argüelles, Klaus Levin, C Popow, Emanuel Christ, R Chetty, L Baillet-Blanco, Jo-Ann Salmon, T Mine, James L. Trevaskis, I Franke, J Gorski, E A Andrianova, A Dayan, A Caballero, Aleksandra Gilis-Januszewska, M Yasujima, Z Kasalová, C.D.A. Stehouwer, F. K. Gorus, G A Nichols, A Glowania, David P. Strachan, P Fredlund, N. F. da Silva, P Reboldi, M Sausbier, K H Groenier, G Stuccio, N Guttman, K R Ahmed, A D Ristic, T Kapellen, J Coutcher, Aldo V. Greco, Oswald Wagner, A Zagayko, Maria Alevizaki, B B Zhang, W F Ferris, Jenny Fredriksson, Lois Jovanovic, J Hänninen, R De Giglio, Kazuo Yagui, O Potterat, P Hamliton, R E Scranton, B Mankovsky, A Stylianou, B Fellström, Abdel-Wahab Yha., M Kitagawa, Katherine L. Baldock, F R Johnson, F Baigts, S D'Addato, F J Sanz, A Mistry, S D Wise, T Pratipanawatr, U R Fölsch, James R.C. Parkinson, Claudia Sommer, C Park, F E Griffiths, M L Martí, R Demirtunc, S Taniguchi, J Lundkvist, T Siegmund, Juan Sztajzel, C Dienesch, F Baumgartner, L Scalone, T M Mckolanis, K Otake, Ullrik Pedersen-Bjergaard, T M Vriesendorp, Michael B. Wheeler, Henry Schmitt, Peter Hovind, S Lange, Stephane Roze, L. Van Gaal, B Klaproth, Anthony E. Civitarese, D Eckland, A Dagar, D F Hopkins, Kari Stefansson, C Gonzalez-Yanes, B Meyboom-de Jong, D. J. Betteridge, K Buhling, M Crepaldi, Ana M. Wägner, L Renna, L Volpe, R McBride, V Corbo, E O Brennesvik, R P Hayes, R Abdollahnia, G Viviani, C F Liew, Francisco Pérez-Bravo, Jeffrey Baron, Brian M. Frier, H H Samira, D Szentendrei, K. J. Schjoedt, W K Waldhäusl, D Gniuli, D Zou, G Tschank, V Urbančič, A L Nolan, Albertini J-P., J Malcomson, M Larbig, C Cheyssac, K Aurich, C M Kesson, S Heller, Maija E. Miettinen, R F Luco, Adrian J. Cameron, Luigi Mattiello, Z. Metelko, X E Zhang, M Parramón, I. G. Obrosova, J Fruchart, M Ilic, Björn Eliasson, Gilles Chatellier, M A Martín, D M Kendall, Holger Luthman, V F Varillas, D Maccubbin, Jang S-A., Amalia Gastaldelli, E Salzsieder, P. de Mol, A Yoshida, H D Lindner, D Gostiljac, M Just, Pan C-Y., J M Fujitaki, G Eiermann, K Bergenheim, A D Frick, A Agacdiken, K Varytimiadis, K Cseh, D A Jackson, S Calderari, Dena G. Hernandez, H M Liebich, K Min, F. de Zegher, Bernd Kulzer, K Han, Ulrich A. Müller, D Marrero, H Hatakeyama, René Koopman, Doo H-K., Petr Wohl, P. Sharp, P Forder, Thor Aspelund, N Meneveau, R M Schmülling, R Aubert, Thom Sam., H Youshikawa, M Ankelo, D Bowden, I Kelly, Frédéric Fumeron, M Sartini, Robert S. Sherwin, L Varadhan, A Criscimanna, John Betteridge, V Jelic, M Bartnik, N Lemke, B Ursø, A Bertoldo, A M Owona, H Okochi, L Pérez-Tamajó, S L Monfre, Daniel Brandhorst, K T Legg, Andries J. Smit, Veronica Sancho, Masashi Hirai, C Klein, Paul J. Thornalley, A Chaidaroglou, K Miura, B Zinman, O M Dvoynishnikova, J Plank, Jan Bolinder, C Lush, B Rubi, R Pozzilli, M Bashir, S A Shtandel, F Mosca, A Naskalska, Josef Vcelak, U Sausbier, P Cavaiani, T U Baehring, Michele Solimena, P Formisano, M Rastaldi, Bernard Thorens, J Ruzzin, E Arbit, M. Hori, Torkel B. Brismar, E Soltes Rak, A Filo, P Heinke, Matthew P. Coghlan, M Masotti, I Perevozskaya, K Ahn, I Moules, K Van Dyck, I Goldstein, Z Mathe, G Z Zhao, S Fajardo, J Taylor, S Chrul, J C Pareja, D Hadjidakis, A J Scheen, N Siddiqua, D C Cavan, R Grella, Krabbe S, H J Rochlitz, A E Hinkkanen, W Wilpshaar, Richard Stevens, M Dreyer, S Hara, X Wang, Melania Manco, D Gillen, Magalie A. Ravier, Olli Simell, John C. Lawrence, Kohnert K-D., Agardh C-D., A Berghold, L Kristensen, Grant Sfa., N Gursoy, Leif Groop, N Freemantle, Anja Schweizer, L Pala, Legros J-J., C. Di Pietro, N. Yamamoto, J Magyar, B Nikolovski, H Ikeda, D Lee, Bruce A. Buckingham, A O Wollitzer, I Kennedy, C Ernest, Neville H. McClenaghan, S Tanaka, Asimina Mitrakou, T Heinze, W Kerner, Moeenaldeen Al-Sayed, Charles Thivolet, L Klaff, A Miconi, Cristina Valeri, J. O. Christensen, K. Ekberg, A Jardine, T Endo, X Zhang, D F Child, A Kienitz, D K Seidel, H. Tada, Sylvie Abouna, Cyrus Cooper, Catherine R Chittleborough, Roberta Assaloni, S Corbi, A K Bose, K Ozawa, C Ahn, K A Deans, G Jackowski, Martin Gibson, Patrick McElduff, O A Mojiminiyi, Manuel Serrano-Ríos, O Dupuy, A L Davydov, Iwar Klimes, Sten-Anders Ivarsson, N Ichino, R Matsutomo, E R Smith, A Stefanovska, B Dehmel, K Koniavitou, E Agascioglu, M Hatazaki, J. M. Gibson, T Yada, P Ribaux, M Rupnik, K Fridell, G Scutaru, L Chugunova, Henrietta Mulnier, A Kendereski, H Lehnert, C Billi, M Sobczak, Francisco M-Mj., L K Archibald, S Sukumvanich, David B. Dunger, I. Benke, G Yillar, N Stingemore, J. M. Boavida, Y Shi, Jimmy D. Bell, L Bozzetto, Andrew J. Ahmann, E Jebens, J Keiding, Elena Henkel, Mark Fineman, J F McRae, Carol Forsblom, S Martemucci, Lourdes Ibáñez, P G Prieto, L Ringholm Nielsen, S Pratas, B von Stritzky, Julio Rosenstock, Lee K-W., J Stocks, L J Strow, I Samarguliani, L Wennekes, R Cheung, Abhishek Nag, Roberto Gambino, Y Suleymanoglu, E Murphy, T T Durck, M F Peyrot, Y Unno, Alexander Mayorov, Eleuterio Ferrannini, D. C. Rao, D Neely, H Karunajeewa, J Palmisano, Julia B. Lewis, M Ravid, G Pons, E Junca, P Vexiau, S Sailesh, D K Miloslavskiy, O N Bondarenko, U Smith, S Torri, Constantine Tsigos, Cesario Bianchi, Mattia Locatelli, D Jaquet, Virpi Lindi, M Moroi, M E Tushuizen, P Pelicci, R Scognamiglio, Pal Pacher, S M Thyssen, A Péterfalvi, Y Ho, S Guntram, L Romics, T Nakagami, Clive S. Cockram, Irina Kowalska, K Brodbeck, Gojka Roglic, J. Dörig, Lise Tarnow, Therese Tillin, A López-Alba, Martin Krššák, Moses Elisaf, S Hata, D P Snoeck, D Schmoll, O V Udovichenko, A Scaramuzza, J Paul, John H. Fuller, Nicholas Katsilambros, Michele Muggeo, Pia Ekbom, Piero Marchetti, V Melki, C Bailleau, H Stavrianos, A D'Errico, Geremia B. Bolli, Amabile Maier, Kelter A-R., Anders Green, Q J Morélis, Steffen Thiel, C Watkins, R C Cheung, A Clark, Elvira Fioriti, N Ari, Nam J-Y., Y Cottin, L G Krinelke, H Al Mohammedi, Simon C. Fleming, C Jones, Z Kerényi, Ahn Y-H., Meile M-J., P Nánási, M Graner, V Canonico, Gangnerau M-N., Hugh R. Taylor, Giovanni Sartore, A. Dejgaard, Carol Kelley, S. Ali, Stéphane Dalle, Jeffrey S. Gonzalez, Elena Šeböková, Alexander Beck, Ingo B. Leibiger, M Rosu, C Pencea, Werner Waldhäusl, Kaltenbacher M-C., R Butzer, S Thore, Adam G. Tabak, Angelo Avogaro, E Standi, Boris Kovatchev, O Bradescu, Patrizia Dentelli, A Fujita, C Verri, R Chlup, Prasad Ydm., S V Hörsten, van der Merwe M-T., D Hilliard, W Klein, D Worthley, M Udvardy, Berit R. Jensen, A D'Avanzo, J Monaghan, K P Yeo, Guivarch P-H., B Bauduceau, D Weghuber, P Tatti, J Ybarra, S Gwozdziewiczová, E Gasparini, B Saltin, Charlotte Granhall, Howard Leventhal, R Marin, M Tumiati, Cicero Afg., L Csémy, B Berger, S Mikros, D Dall'Asta, M Shahmanesh, Y G Vasiljev, F Potthoff, H S Randeva, G De Berardis, J O Logan, K Warncke, P Uitterlinden, E Rehring, K Gilmore, K Shankhdhar, V V Bojko, M Vahatalo, E A Korolyova, D Wiemann, P G Lankisch, D Hendrie, F Galtier, M Rybarczyk, Gisela Dahlquist, N N Rudovich, G Stein, A Liebl, F Tan, A Westerlund, S Gronemann, I Franklin, Jonathan A. Prince, Peter Arner, E Skliros, T. Sparre, M Vigas, Maddalena Trombetta, L. Bjerre Knudsen, A C Sima, I Dubroca, Alastair Gray, I Weets, R Ferraresi, Schauer Ujw., E. Leinonen, S Corazza, Jonathan Levy, P K Prakash, R Guzder, S. Barnhill, John Blangero, J Herreros, G. de Vries, Cheng Ptw., A Macías-Batista, K. Capito, R Thomas, G Thomas, G Boemi, Lotte Pietraszek, Pierre Fontaine, I Holme, J Smedegaard, C A Harrop, U Helwig, B Levy, A P Gribben, Hiroto Furuta, P Beckett, S Giannini, Ruth L. Coleman, Eva Fernqvist-Forbes, N Cugnardey, A Dumas, Jane Pinaire, S E Hofer, D Shimono, Erik H. Serné, Alain D. Baron, C Battista, M Tanen, M Klementova, V Adams, J Komorowski, Antonio Nicolucci, E. C. Burns, H Sydall, M G Fanara, M G Giovannitti, N Okabayashi, Magdalena Szurkowska, I A Eroshkin, M. I. J. Uusitupa, D Ma, C C Dieguez, J Sutcliffe-Goulden, A V Gaddi, Michał Arabski, Serge Halimi, Wendy C. Burns, S Seclén, H Sugano, A Vinterby, K Backx, L F Diaconu, Fernando Gomez-Peralta, O'Harte Fpm., G Lepeniotis, D Laune, H Kvasničková, N H Wallén, G Boner, G Cieślik, Robert Hermann, Paul Q. Thomas, Y Kumon, Maria Maiello, M Atkins, Kenneth A. Earle, Guowang Xu, H Y Bae, I Reynisdottir, D Perez, D E Cannon, P Fabietti, I Geronooz, J Østergaard, K J Jeitler, S Skourtis, A Zambanini, A Saemann, K Kuboki, Helen L. Lutgers, A C Thai, Arne Melander, D Pinkowski, S G Straub, S A Wolfe-Coote, A Totora, Hayley Dickinson, A Lindenmair, A Ginis, I Faturos, F Van Eylen, C Huard, F Fu, N Wang, B M Rasmussen, Angela Napoli, L Granato, Markus M. Lerch, M. Frandsen, A Lyras, Lawrence S. Phillips, J Mabley, R Goldschmeding, B K Kilhovd, W Liu, Greg Poffenberger, P Cipriano, Anna Maria Charlotte K Lindqvist, A Matsuzawa, J Wang, T Yu, M S Pepper, Lena M. Thorn, Y Sakamoto, Blanche Schwappach, Anna L. Gloyn, P Dupraz, A. M. Schmidt, M Psallas, V Tsirimbis, Carl D. Langefeld, D Sass, H E Scholtz, M. Cailleau, Lauren Julia Brown, K Phillips, M. Iezzi, C Jayawarna, Eleni Anastasiou, R Lobmann, R Lundershausen, H Fujiwara, H R Nan, I C Smith, I A Karpova, A Navazio, S Kang, T. Hansen, T Watanabe, Gang Hu, Malik Rja., T Kennedy-Martin, Ulla M Smidt, J.M. Dekker, A A Fisher, H Liu, R E Pratley, B Sun, C Fledelius, J F Raposo, R Langham, Ahn S-Y., B R Waterhouse, Shaoping Deng, W Ricart, S V Melnichenko, Henrike Sell, M. Tomalino, N Takeda, Paola Massucco, A Harlan, W Henrich, C D Byrne, R Junik, Khalid Hussain, D Pop Gorceva, Torben Hansen, C Ritterath, K Ogawa, D V Phan, Bradley S Metcalf, Robb E. Moses, Juan P. Frias, Hitoshi Ishii, C Brisard, P Wolkow, H H Maurer, Ingo Rustenbeck, Juris J. Meier, Octavian Savu, S D Lin, V B Bregovski, A Fox, S Cicala, M. Koenen, L Vignati, O de Divitiis, Constantin Ionescu-Tirgoviste, Kilian Rittig, J Song, Riccardo Candido, F Cohen-Boulakia, U Shankhdhar, P Jahan, Antonio Tiengo, E Liepinsh, C Álvarez, Sigurd Lenzen, James E. Foley, A. del Arco, M A Maitan, U Mollenhauer, M A Na, A Beha, B Aicher, Gabriele Meyer, E Sommariva, J Åman, B Gmeinhart, Theede A-M., Bjorn Bolinder, Giulio Ceolotto, S Sbrana, F Biarnes, Damini Dey, Barbara Thorand, H H Klein, Juliana C.N. Chan, L Piconi, S Gudbjornsdottir, E Bobbioni-Harsch, Joanna Polanska, Cristian Serafinceanu, S Gambardella, Olivier Huber, J D Brunzell, T Nagasawa, Loretta Vileikyte, A Szocs, H Löwel, Z Lin, Anders Juul, H Tsuneki, L Sauriol, G Siebert, Marit E. Jørgensen, K Matthies, Brian D. Green, P Jurowski, Z Gao, M Furuya, Silvia Manfrini, Efthymios Motakis, E Souvatzoglou, Qian Y-Z., Byun S-H., T Nguyen, M R Anwar, Geltrude Mingrone, B. Idzior-Walus, Mamas A. Mamas, G Scholl-Schilling, C Bittner, A E Raptis, L Laghi, Murray Stewart, M Orel, Janet M. Bryson, Chris P Gale, Åke Lernmark, A B Escorza-Domínguez, C Fuentes, A S Einarsdottir, M O Akinsola, P Maisonneuve, K S Leong, B Missler, Simona Frontoni, Con Tsalamandris, Flavio Francini, D Rouiller, B.E. de Galan, Girolama Alessandra Marfia, M Fioravanti, A E Weber, M Nargis, P Nowacki, Y Chen, B Larsen, Ruth E. Gimeno, A Wojciechowska Luźniak, R Meisterfeld, Limei Liu, A Ohashi, T Pieber, Bin Yao, G A Herman, M Pallini, R E Honkanen, H Nyblom, R Humbrecht, Takashi Tsuboi, Pinar Topsever, Monika Kellerer, J Woods, Steen Stender, C Kapitza, Sherwyn Schwartz, M Taskiran, N Hashimoto, A Jabin Gustafsson, K C Silva, I Nitz, S Dzienis-Straczkowska, H Elouil, L Sommese, Patricia A. McKinney, S Ogawa, E Carr, I Porchay, Robyn G Langham, Bruno Vergès, K H Usadel, S Sivakumaran, H M Hearnshaw, José Luis Santos, R Ishibashi, F Huq, Lebrethon M-C., Z Leshchenko, Elisabetta Torlone, A Saltiki, A Plaschke, Wolfgang Koenig, D. D'Avola, C L McTernan, Haruhiko Osawa, G Cazzetta, S J Lee, S Al Jebely, Hoogma Rpl., A Shimizu, Tack Cjj., Itamar Raz, Adrian Vella, P. B. M. de Andrade, Aguiar Lgk., Wolfgang E. Schmidt, T Wolthers, W. Gatling, T S Purewal, Philipp E. Scherer, E Heller, Stephan Gielen, Jo S-R., Monica Vedovato, L Nosek, R Ryder, G Giassakis, A Cretti, A Wajngot, T Waldhör, S Zoric, H C Lee, L Pulkkinen, L Lacey, I Tomescu, R S Patarrao, X C Liu, Lauge Schäffer, Jarkko Ustinov, Anders Thorell, K Kangawa, P J Wood, T Yeoh, Jo Satoh, G Psaras, Volker Burkart, Karin Schindler, Dario Pitocco, M Kolopp, Gabriela Roman, E Renström, M Goldberg, M Beregszaszi, S Senkel, M F Meyer, María Luisa Villanueva-Peñacarrillo, Elena Beltramo, J E Snaar, A Hayward, C Abreu-Padí, S E Vielwerth, R Krones, C C Stanciu, M Izquierdo, I Elbing, R Astorga, V I Bouloukos, P Zabielski, S Precerutti, Kang S-Y., K L Pratt, Joost H-G., Matthew L. Iorio, Naomi S. Levitt, Yutaka Seino, Peter A. Gottlieb, I Ehrén, Y Matsuyama, Jean Claude Mbanya, S Parveen, R Purvis, A Cappadona, V V Afanasyeva, K Löbner, S Del Guerra, V Valle, Victor A. Gault, M Tan, M M Budge, I Ioannidis, M Ishizawa, Castelli, D Nowak, János Rigó, Claudia Bleck, E Degli Esposti, C Tortul, M Klebach, E Schvarcz, L Pauline, D Krusova, J Csillag, Park K-G., Kaichi Kida, P Bialasiewicz, S Seeliger, B A Williams, P Mistry, T Nicer, N Ahmed, H Ohashi, Peter Achenbach, van Hessen Paw., Jesús Cancelas, E Cizmarova, D Takahashi, K Tanaka, A M Rojo Llobet, Q Chen, A J Garber, P Halban, B Brunmair, A Barthel, M R Katdare, Dominique Laude, M E Pavkov, C Leach, C M Breschi, S Okada, B Balent, Ornella Massa, Ravi K. Garg, van Loon Ljc., K Obuobie, W Moll, L Varanese, V Smejkalova, B Royer, M Roth, M Belfiglio, Chae M-K., I Kimura, Casper G. Schalkwijk, Hans-Jürgen Hedrich, Heinsbroek Acm., Jared Rutter, Ken Williams, K O Lee, A N Symeonidis, J B Brown, M Pfeuffer, W. C. Knowler, A N Barsukov, A Woods, T W Kim, Khalid Bak., Andrea Mari, David J. Pettitt, Y Tomioka, J Hochman, Mireia Mora Porta, K Pagava, Krzysztof C. Lewandowski, J Taton, T Yasaka, M Tyrberg, M Sargin, P Szenthe, R Sicree, C Abreu-Padín, Magdalena Lundgren, J Radziuk, Eili Tranheim Kase, W L Goudzwaard, Yanbing Li, E Ramos, H Monastiriotis, J Cur, S Pu, Lakka H-M., Park J-S., Fabrizio Barbetti, S. Ciani, Pavel Flachs, N C Correia, Angela A. Rivellese, F Ebara, Nicolas Musi, H van Ahlen, Helen M. Colhoun, Anna Czech, Steen B. Pedersen, N Jost, N Da Silva, J Nóvoa, Y Onuma, Anna Körner, D Michael, M Straczkowski, I. Truyen, R. Schmid, Søren Paaske Johnsen, H Koenig, B. Miranda-Palma, E Wasén, F Pervin, P Cavallo-Perin, M Niessen, E P Shavrikova, P Tarkun, M Vavlukis, H Gang, O Sánchez-Vilar, C Dalla Man, S. M. Haffner, R Eggertsen, L Pucci, F T Fiedorek, E I Mainas, H Holdass, Peter R. Shepherd, A Banu, R Lichiardopol, Lee M-K., N Zaytseva, B Gumbiner, Strotmann H-J., L Y Baranova, A Kissebah, A Pezzatini, I Kharroubi, N A Thornberry, A J Buckley, B Pontiggia, T Chen, M Ikebukuro, J Leach, C Frost, J Han, H Hashizume, G Poulsen, H Eckert, Paul Zimmet, Lee J-H., Peter E. Heding, S A Ross, Nils J. Færgeman, Giuseppe Penno, T Varbanova, H S Shon, Z Canturk, S Akahane, Noel G. Morgan, A Sener, Seronde M-E., P K Thaware, W Insull, S Forst, K E White, Christoffer Hedetoft, M R Holland, K Okamoto, F Yamagata, Markus Lassila, N Tanaka, Kristian Midthjell, R Isoaho, D A Legemate, M Motzkau, Y H Kang, A P Nescheret, J Boiko, Hemmo A. Drexhage, Gagik R Galstyan, Naim Shehadeh, Henning Beck-Nielsen, T I Justesen, O Kalter-Leibovici, T Vahlberg, M Mozdzan, G Siegert, V Dumenil, Katsumi Eguchi, J A Vazquez, Sally Hollis, H Haberland, A Souvatzoglou, M L Gavete, K. S. Nair, Katharine R. Owen, C Garcia-Rodenas, Gerald I. Shulman, Peters, H A Parkes, Y S Kim, Mats Rönnback, Isabelle Leclerc, Marie-Hélène Giroix, I D Caterson, S G Rønn, L Scionti, Silvia Pinach, Hans Christian Reinecker, Kathryn Noyes, P McTernan, C Y Tan, N. Lalic, Richard D. Carr, M. Toman, D Papazoglou, Domenico Bosco, G Lübben, F. Costanza, Tania Maffucci, Jonas Nygren, Ole Lander Svendsen, Kristin Taylor, Ugo Boggi, A Kayserilioglu, Gudmar Thorleifsson, G J Dunseath, B. Balkau, T Zieher, M Schwarts, A. R. Cobitz, P de Pablos, I Recas, Carlos Lorenzo, Pamela J. Shaw, Y Cho, C Münscher, Anna Maestroni, Milan Zdravkovic, Gerstl E-M., L L Xiu, Yoshitaka Kajimoto, A Deb, F Osaki, G Kirilov, B Staffler, Běla Bendlová, M Rebelatto, Frank Reimann, B Ø Christoffersen, S Durant, Fruchart J-C., Ravinder J. Singh, V Connolly, Q Zhang, Alexandra Kautzky-Willer, Francesco Andreozzi, N Talai Rad, V Loyková, Trampisch H-J., Stefano Menini, F. Rodríguez de Fonseca, W Hanif, H J Böhles, S Fotiadis, Philippe André, T Kubiak, T Friede, J Murin, Erwin Schleicher, Adam Garrow, M Takahashi, P Valensi, S Pappas, E Lim, D N Staroverova, C Tadgell, C Dessapt, Brittany A. Rasmussen, L Cheung, L E Porter, R Ishihara, J Ravisy, T Inukai, Christine Winzer, E M Özer, Nish Chaturvedi, Ana Chico, Ville-Petteri Mäkinen, N Bellili, Howlader, Jansson P-A., A Martella, Jan Frystyk, T Kakko, K Hershon, S Hoashi, B Nag, C Chabrolle, B Leatherdale, J. Lu, Stephen Colagiuri, C Brendel, Michael Roden, Peter Clausen, A L Macdonald, R A DeFronzo, F A VanNieuwenhoven, Sirkka Keinänen-Kiukaanniemi, Jonas J-C., Hobbs Fdr., H Uchino, S Del Prato, E Polakowska, L Shankhdhar, Hedrich H-J., S Rodriguez-Cuenca, A Schwarzmaier-D'Assie, K Fukuda, Robert H. Eckel, A. Hilding, A Rutscher, D Kerr, Junhua Li, C. Köhler, A Banaszak, Peter Lönnroth, P Wulff, M A Gruzov, Fariba Shojaee-Moradie, S Matsumoto, J P New, N Barthes, M G Leyck Dieken, Mian Li, O Ivanova, G Papalia, K A Nilsson, Parving H-H., P Merz, M. A. Schweitzer, A Morris, P. Andersen, O Tschritter, M Fitch, V Fejfarova, Elisabeth Bernroider, E C Kiawi, M de Kerdanet, Claus B. Juhl, C Taxvig, Kerstin Berntorp, Birgitte Andersen, C Coscelli, C Ktori, Norio Abiru, R Mössner, Hiroko Hirooka, Jens J. Holst, Q Dan, H F Gu, C Gimpelewicz, A Oeckinghaus, B DelBuono, J Kuroda, P Kastner, Clemens Fürnsinn, H Usui, R Mosqueda-Garcia, P De Meyts, K Yamagami, M Tóth, V Leite, H Alberti, M Meneses, Gregory Collier, E G Starostina, C Delaporte, Agostino Consoli, François Alhenc-Gelas, S Tonstad, G Schuler, J Juszczyk, G Hoefle, M Wilken, Mark A. Yorek, Volker Lodwig, G Edwards, E Catellani, Ewa Wender-Ozegowska, Kurt Hoffmann, I Markova, Steven J. Hunter, A Venkataraman, Bente Klarlund Pedersen, A Kengne, Ken K. Ong, L A Calo, M Huckova, Y Morikawa, Pierina Richiusa, D Giuffrida, Sonia Brichard, Giuseppe Paolisso, Andrew T. Hattersley, M Vankova, Jon G. Mabley, G Salvidio, M Montolio, X Yang, Barbara N. Campaigne, Ralph R. Turner, Andrew J.M. Boulton, P Johnston, S Berchtold, Roger Corder, D Ledwig, M. Di Mauro, Houweling, J H Bowker, J Hilsted, Shin D-W., B Kiran, E Esteve, A J Cameron, S Spera, Kathrin Maedler, S Tsujii, J. H. DeVries, S Cailleaux, M Walter, A Florén, R Lehtonen, Davis Tme., N Patsourakos, J. Marco, G Lepore, L Morcillo, J Burén, Paul Smits, Juraj Koska, Chung J-H., Katherine S. Elliott, Bong Soo Cha, Christian Weyer, F Montorsi, L G Søndergaard, H Horie, M Herten, N Aghamohamadzadeh, L A Scrocchi, A Oyarzún, Rutten Geh., K Yamada, M Zivkovic, R S Beifort, Lee I-K., S D Bouman, H Böhles, Dwight E. Matthews, Orville G. Kolterman, Bidda Rolin, I Shymanskyy, P Thomakos, John Strand, A Virkamäki, C M Clark, Y Tokumasa, Odusanya Pot., Joel F. Habener, Abel López-Bermejo, Anders Tengholm, D Argon, Lajoix A-D., N Aki, L Kessler, N Takahashi, A Zmysłowska, Kåre I. Birkeland, D Soon, Lars Køber, M Vaňková, Lee W-C., F Payeras-Más, C Lau, E Ramos Lopez, L Lukic, A Suehiro, Stephan J-A., I Estalella, Jørgen Jensen, Liaqat Ali, V S Dimitrijevic Sreckovic, V P Maximova, G Salietti, M Ding, Yuksel Altuntas, Chung K-D., F Kaufman, Ludwig Wagner, C Calvi, D X Gram, David G. Bruce, K Sprenger, M Schweers, D Kush, D B Panagiotakos, J. M. Currie, Luis Castaño, Dag E. Undlien, D. Haspel, A Suzuki, J Cederholm, S Garcia, L Cynober, P O'Hare, A Tsur, Christine Zimmermann, M Faimalie, V V Poltorak, S Alba, Axel Haupt, J Varga, Tetsuya Yamada, M Shoji, R H Lloyd-Mostyn, Péter Pusztai, Doney Asf., M N Gangnerau, I Shimizu, Henrik Ortsäter, F Liska, Mandeep Bajaj, H Sarui, Michal Andel, S Chiheb, Diane Barker, A. van Tol, Brigitte Reusens, I Anafaroglu, Giel Nijpels, F Bongardt, K Taxildaris, M. Orsini Federici, V A Horton, K Ota, A McCall, M Vladica, Anita M. Hennige, Karsten Müssig, A Philotheou, I Chronopoulos, N A Perrin, B Janand-Delenne, Søren S Lund, S Duarte, R Bernardi, R Holman, Safia Costes, Hubert Kolb, G J Schlömer, Rainer Lehmann, Lusson J-R., J K Malone, X I Nkomo, Lars Melholt Rasmussen, E G Chittilapilly, J Satrústegui, A M Abbatecola, M Cristini, U Hanson, María Teresa Martínez-Larrad, Frida Renström, Luigi Uccioli, A Hennige, T Akhobadze, U Raval, D J McCarty, Didac Mauricio, S Horiuchi, V V Nosikov, B Wierusz-Wysocka, K Xiang, H L Fehm, Elaine Gutierrez, S Salman, E Siekierka-Kleiser, P Martul, N Kajaia, A W Herling, Tony R. Merriman, Kirsten J. Ward, René Gross, S K Althouse, S Woodhead, Emmanuel Cosson, T Rönnemaa, T M Filiz, Jerzy Loba, S Sha, Klas Malmberg, Carlo Pesce, Jung D-S., I Majdrakova, Thomas Forst, M Schütt, Hierl F-X., A M Efanov, I Verschraegen, H B Jensen-Holm, D Deckhut, Frida Leonetti, N Selzle, G Cassetti, Jose L Mesa, G Morrison, Christian-Heinz Anderwald, C Kliebe-Frisch, J H Moffitt, P Lahm, Hiroshi Ishiguro, E. Borgo, A Keech, L Quagliaro, Thomas O. Ola, Henquin J-C., W J Sluiter, F Leprêtre, Kalliopi Kotsa, Peter Karl Jacobsen, E Sanchez-Largo, E Gaia, Daniel R. Witte, Sidsel Graff-Iversen, G Seebohm, E Cacès, R G Khalifah, W Wilson, Avan Aihie Sayer, C Raffaitin, J Gumprecht, T Lehmann, E Migliaccio, R Urrutia, E Shelestova, A V Chervonsky, Stefan Mustafa, Y Hisano, Erik A. Richter, J Miettinen, K M Gottesdiener, Gangyi Yang, D Chevenne, A Girach, P Samuelsson, Taskinen M-R., D Ciociaro, D Aydemir, Yang S-B., P De, Dongliang Zhuang, Nathan R. Hill, B V Hansen, Hideki Katagiri, M Saryusz-Wolska, G Y Gandhi, Nicholas Witt, D Berzi, B J Mejía-Pedraza, D G Burrin, R Mather, V Ashkenazi-Katalan, Y Yamasaki, G B Jensen, Emma L. Edghill, Y Wang, I J Deary, M Langenfeld, J L James, K Yozai, T Appleton, Jamal A-M., A. Di Benedetto, Yutaka Nakaya, Elin Rebecka Carlsson, Y Park, T Carpenter, Attila Bokor, Patrick Harriott, S Ait El Mkadem, B Lormeau, A Ceylan-Isık, Stefania Bandinelli, Isabel Valverde, N Brevnova, Pietro Passera, F Escrivá, J El-Din, G Ertl, Tringham, S Wakabayashi, J Soler-Soler, T Tenenbaum, Kurt Widhalm, S Yoshizumi, M Masin, L Tsibina, S Shutler, Kirsten Ohm Kyvik, Nigel J. Crowther, M C O'Neill, A N Pehlivanidis, A Kürklü, P Bouter, Savontaus M-L., Sharp Gwg., Kivelä S-L., A Krasner, E Carrasco, Ravi V. Shah, A Skytthe, P Roca, B O Boehm, Felicia Ranta, Ulrich Werner, A Shearer, D Hosaka, P Papadimitriou, C Dimosthenopoulos, L Farkas, K Short, S Futakuchi, Z Garamvölgyi, C Hohberg, B Heckmann, M S Fineman, H Akahori, Yasuhiko Iwamoto, K Hashimoto, Zhihui Zhong, S Shubeska Stratrova, G M Cvijovic, C Neumann-Haefelin, Amna Khamis, J D Betteridge, P Fratino, Itxaso Rica, L Tsutskiridze, S Nakajima, S N Koval, Paolo Brunetti, J Buithieu, A K Rasmussen, John P. New, V W Rahlfs, S Pellitero, Claude Bouchard, P D van Poelje, A Ghio, S Barcelo-Batllori, B Götz, Fernando Djs., Antonio E. Pontiroli, P Lim, M Eckhard, Norbert Stefan, L Alviggi, G A Thomson, S Bergmann, E De Amici, Elisa Pagnin, C Gatsiou, Markku Laakso, M. Massi Benedetti, Szabo, E R Trimble, H Konya, T Örn, G Valsamakis, J Zhang, S Mcintyre, H Yu, C Huang, Ken’ya Sakamoto, David A. Savage, Martin Whyte, S Vakkalanka, G C Webb, R. Reitano, D James, D Bradshaw, K G Parhofer, Napoleone Ferrara, P Boucek, Henry J. Dargie, V Artikis, R A Flett, Giovanni Anfossi, I S Simeonov, D J Drucker, A Chamson, Phillips Diw., Charlotte Malis, Bernd Schultes, M. I. Hawa, Shanta J. Persaud, S Geloneze, J Sponarova, S. Lahdenperä, Y Komatsu, B Capaldo, Wojciech Młynarski, D Brasacchio, G Allochis, H Takeda, W Doering, J Grimshaw, Ichiro Niki, D Degiannis, C Köder, Carla Iacobini, Norbert Hermanns, Voss, A Grimaldi, R. Wassmuth, L Bernardi, A. Crinò, T S Temelkova-Kurktschiev, C Nita, Michail Antsiferov, A Balini, Yoo H-J., Giovanna Oddi, A C Bossi, D. S. Harry, Á Vatay, Peter R. Flatt, M Fukumoto, Sebastio Perrini, Halfoun Vlc., R Helal, Donald C. Simonson, B L Shine, E Maltezos, J Ryskjær, H Bessho, Yoichiro Kamatani, M Veitenhansl, M Farnier, N Hole, M Abbasi, Cha B-Y., Gall M-A., M Bogatean, Amitha Gopinath, M Vettore, O Seda, V J Willey, Carl Johan Östgren, R M Parhimovich, Rennings Ajm., B G Kravitz, D Lipkin, Andrea Galgani, A Nakajima, Alvin C. Powers, J E Paiker, E Souhami, Per Hildebrandt, Charlotte Kragelund, C Lindloh, M Sasaki, Torben F. Ørntoft, Nilima Biswas, G Giani, J Lazarus, H U Janka, H Li, F Reeß, S Athanaselis, S Sankar, Carlos Hernández, A Tone, R Capani, E Biermann, C. N. Hales, Petersen Jla., M Federici, Torben Jørgensen, P Kurtzhals, Michael N. Weedon, Eva Lind Rasmussen, Rupert Beale, B Leiting, Per K. Christensen, R J Young, M J Wooddell, Guy P. Nason, Jean-François Martin, J A Ruggles, C De Natale, Renu A. Kowluru, Alexandra Schneider, M E Cerf, S Galande, V. Miselli, Romano Regazzi, I Gkioulmpasanis, D Voinovich, Susanne Ullrich, Zhao P-L., R Rabasa, W G Towers, D Cerrato, G A Nuttall, Halimi J-M., Marco Falasca, Antonio Zorzano, D Bottino, C J Mullany, Michael Alvarsson, Matthias Nauck, E Pankowska, S Bulgurlu, U Hoss, Eiji Kawasaki, Davide Lauro, Ha Kbn., Beauvieux M-C., Enzo Bonora, J Lane, H Mahtab, N. Klöting, D L Winter, Freyse E-J., G. Biemer-Daub, Cecilia Invitti, J Dabrowski, Laurence Ladrière, Catherine Born, A Hiukka, Y Inoue, M Cimmino, Y K Kim, Jeanette Kuhl, J Peiker, J Szánthó, B. Zierhut, P Blazicek, M Calbacho, L Marenah, M Zbinden, Y Nakasone, David R. Owens, P Ross, T Vilsbøll, A Šmahelová, E Boldrini, S Santos-Palacios, T Krarup, J Bonnet, Dorte Vistisen, R A Ritzel, Tsuguhito Ota, L Guja, B Chappuis, Nils Billestrup, A Grilli, Polly J. Bingley, Sabine Fischer, Kenneth Robertson, P M Bell, R Coll, Y Uchigata, A Glebocka, L Rizzo, Swangjit Suraamornkul, Egberts E-H., E Zapanti, K Oi, Hideichi Makino, N. Visalli, Häkkinen A-M., Uwe Voelker, Ian Lawrence, Marju Orho-Melander, Mary-Elizabeth Patti, K Herrmann, B Hultberg, Hoekstra Jbl., Nael Shaat, Hannele Yki-Järvinen, E Canbek, E Madarász, A Marsocci, N A Foxwell, P Sorichetti, Eva Aguilera, A Bronisz, J LaSalle, M Freeman, M S Kipnes, K Ažman-Juvan, Stefan R. Bornstein, Y Kainou, Francesca Porcellati, Bart Keymeulen, Y Takemura, Joanne Rasschaert, L Juurinen, M Broch, Paddison Cam., Jens Faber, M Sanges, R Swift, S D Luzio, T Kuchmerovska, J. De Schepper, Sabina Baumgartner-Parzer, C. Herder, Peter Rossing, C L Frost, K Kaku, Zhiguang Zhou, Thomas C. Wascher, Song B-R., S Bai, M Vázquez, B. Van der Auwera, A Pavanini, Luisa Gilardini, K S Sunnerhagen, Claes B. Wollheim, S Shinn, Christian Dina, Yoichiro Iwakura, L Thomas, K C Lasseter, J Crook, V Kraft, C. J. Bailey, E Estimes, A Jiménez, Georgeanna J. Klingensmith, G Menzinger, C Rinsch, Anna Jonsson, Masakazu Kobayashi, A Goertz, K Papatheodorou, J. Lopes de Faria, C Karasu-Yilmaz, C H Hobbs, J Behjati, R Buckingham, A Patruno, A Heinrich, L. Kalbe, A Oglesby, Y Fujita, O Zacharopoulou, P Di Fulvio, G Poggi, J Jowett, W Isley, Susumu Suzuki, M Zamaklar, A M Carter, S. Efendic, Claude Knauf, Stephen B. Williams, Wu H-S., S de Kreutzenberg, Susanne Schwenke, A Coppelli, S Maxeiner, E Stridde, M Zurawska, J. H. Fuller, P Di Tomo, D Pisarczyk-Wiza, J Dudenhausen, Robert G. Nelson, Catherine Pihoker, M F Bullano, Tuomo Rankinen, J Wada, R A Greiner, L A Tchugunova, T Okada, M Bosevski, G Dentan, S Bruce, H Rittmeier, I Peovska, B Augendre-Ferrante, Zsolt Bosnyak, H van Wasen, Peter Almgren, Lut Overbergh, Bernard R. Landau, D Schumann, Frédérique Diraison, B Dietrich, Q Zhou, Alan D. Cherrington, Ottavio Giampietro, Margaret M Band, G Brandrup-Wogsen, R Eher, N Kim, Merlin C. Thomas, V Anand, K Szosland, B Gustafson, Aina S. Lihn, Mamputu J-C., Dosch H-M., G Paragh, Robert E. Ratner, C D Kim, A Heckel, Adrian J. Bone, V G Athyros, Léopold Fezeu, M A Denke, N Karlovich, M Morgutti, N Villela, Mathias D. Brendel, Peter Krippeit-Drews, Akira Matsutani, Gyula Tamás, Ole Schmitz, Chae S-H., J T Willerson, L Galuska, A Vanoli, G Habib, Giuseppe Remuzzi, R. R. Rizza, R. Sillard, S Longhitano, Hongliang Li, Y I Karachenzev, J Denne, M Grenningloh, J Hayes, B J Goldstein, S Erdmann, A Midtgaard, D F Giannakopoulou, Dick de Zeeuw, A. Holstein, J Brązert, M Zmudzinska, R E Davis, Felipe F. Casanueva, F Huet, Stephanie A. Amiel, Y Miyake, N Hiroi, Eberhard Standl, G Sebag, Caroline Kistorp, R Jaziri, Rita Basu, M Mertl-Roetzer, Flavia Franconi, U. Di Mario, M Brammer, U Langel, Meghan L. Marré, F Garcia, G H Thoresen, Ingrid Kockum, H Gin, L Sedova, Susanne Rudberg, Martin Prázný, Diana Rubin, I Kyrou, T. J. Wilkin, A D Kriketos, E M Egido, K. Sugimoto, Janssen Pgh., E Aktas, E Rylander, M Ramazashvili, Hans-Ulrich Häring, Mackay Djg., J Skupien, Yoshihisa Nakatani, I Karádi, Jurg Ott, H Makki, A J Ló, T B Bödvarsdóttir, Timo A. Lakka, J Nerup, Anders Rasmussen Rinnov, F Assimacopoulos-Jeannet, G Beretta Anguissola, F U Rodriguez, A Garcia-España, B Neve, P Curtis, M Boldrin, E Csongradi, M E Hossain, Jürgen Kasper, Concetta Suraci, Lex M. Bouter, Z Skrivanek, H Bischoff, H Yamazaki, Nicola Jackson, Irene M Stratton, D Vogelsang, E Baranyi, Andrei I. Oprescu, X Yan, L A Resnik, A Wajman, M J Sheetz, R T Ribeiro, K Oono, Angelika Thon, A H Boss, K U Wittrup-Jensen, Nanne Kleefstra, E. Ferrari, Thomas Strack, Häring H-U., R Chow, Gabriele Perriello, R Z Timar, R Giannarelli, Y Saito, Thomas Mandrup-Poulsen, Peter Bergsten, D Raunig, A Rovira, Gunnar Sigurdsson, Z Melczer, L Gu, R Elli, C Chan, F N Wang, Carmine G. Fanelli, Thomas Illig, M Szabó, K Holtz-Neiderer, R Kominato, Nieves González, M Pfohl, D. P. Bataille, R Peter, Robert J. Heine, E Bacillo, S J Creely, D Bruttomesso, D Karagianni, I O Shymanskyy, Lüddeke H-J., D P Kurktschiev, H J Kim, K Nanjo, B R Lee, Valeriya Lyssenko, Y Hasegawa, P Langer, C Gemma, Martin E. Fernandez-Zapico, Dale S. Edgerton, C Romano, Sotirios A. Raptis, S Ishida, S Frantz, U Ott, D Simmons, Philippe Morel, P M George, E Müller, F Saleh, M. Grabert, John A. Todd, V Golozoubova, M Sikter, Carla Giordano, P K Awah, M Colding-Jorgensen, O Schoeffski, T Suda, A V Kulikovskaya, T. Lauritzen, Y Fujii, Philip G. McTernan, G V Donchenko, D P Hancock, G Renier, G Maclaine, Nita G. Forouhi, O Kolterman, S Nag, Bengt Vessby, J Genescà, D Moruzzo, P Dittrich, Aristidis Veves, M Sacco, Christopher Shaw, F Agrò, F Oana, I I Dedov, P Sergeev, A Sotiropoulos, L Moretti, Paolo Pinton, Nigel P. Jones, K Takemoto, Mary A. Cotter, Mauro Castellarin, N Roper, Peter Gæde, E Cerasi, T Hoffmann, D Gabellini, Ramzi A. Ajjan, Y Yu, Huh K-B., G I Kuntchevich, Kenichi Shikata, U Puch, Hirofumi Misu, P García, J Shen, S M Katzman, Marco Castagneto, H H Hundborg, E Kaszas, Choi M-H., R Battiato, H Shi, Y Oh, Adela Penesova, C Xipnitos, Julie C. Price, T Imamura, A M Tonkin, C Tang, A A Barros-Filho, N Chartrel, A Findlow, Z V Caparevic, Jukka Westerbacka, T Ishii, A R Vlad, O V Tuzova, M Y Gorshunska, Knut Borch-Johnsen, P Pizzocri, Bernt Lindahl, T M Wallace, H C Deng, Mikael Knip, M Shimodahira, Renato Lauro, F Zelaya, Giovanni Pacini, I Franzetti, E Karagiannis, L Wood, Wendy A. Davis, Karen J. Mcneil, M Scott, Mariella Sorcini, G Lasfargues, Philippe Froguel, Kjersti S. Rønningen, R Chotmongkol, G Zasadzinska, R Iakoubov, E Kiwanuka, M Arribas, M Schuler, K Pyörälä, H. de la Calle, Maciej Wideł, V Lowe, Ilaria Dicembrini, D H Beran, R Morikawa, K Satani, G Scarselli, Lea Bruhn Nielsen, Ahn Y-M., Aveni Haynes, Leslie Rdg., Basem M. Abdallah, K V Allen, Max Bulsara, Masataka Kusunoki, D L Duhamel, F Cipollone, Lee S-J., È Palik, A I Gladkich, T Sato, Yogish C. Kudva, L Gardete-Correia, Yoshinori Hinokio, Martin Rossmeisl, Lorena Amadio, G Gates, K Wittrup-Jensen, A Pfützner, E Tourel, V Moya-Suri, Y Imai, U Zeymer, A I Santos, J Mueller, M Lombardi, K Luz, Olga Kotova, Angela Scipioni, Bernard Portha, Reinhard G. Bretzel, Risa Ozaki, I A Katz, L Dakovska, Sampath Narayanan, T P Levchenko, M Lazarova, J Stock, D D Kim, J J Vendrell, Heikki O. Tikkanen, Ostenson C-G., Ronan Roussel, Hideaki Nakagawa, Gabriel I. Uwaifo, Paul D. Griffiths, Klaus Moeschel, Lee B-W., I Rojas, K. Staiger, Brendan T. Kinsley, J Gebel, Alessandra Bertolotto, Anthony Zagar, Domenico Accili, Richard H. Jones, A Mayorov, J M Morrell, S Soedamah-Mathu, R Obrenovic, T C Cavakcanti, J Łopatyński, Ottavia Porzio, A Barbera, R Piechatzek, Ewa Małecka-Panas, M M Mocanu, David W. Dunstan, A Y Tokmakova, Sei Hyun Baik, A De Bellis, D Kallend, D Melloul, C Rosak, S G Paule, Vicki Thallas, A Schrodter, P Roesen, G M Steil, Sabine E. Hofer, P Juretschke, D Zozulinska, Slavisa Ninkovic, V Pauvaday, D A Darko, Kim J-I., David R. Tomlinson, Fach E-M., A Papaefstathiou, L Gürtler, N Wiernsperger, J Simcox, L M Dickson, S Fujii, J Schwarz, Lars S. Rasmussen, M Trautmann, M Uzan, A Sato, Hans Günther Wahl, Tore Julsrud Berg, Kar Keung Cheng, C J Emery, M Lipsett, U Belz, Majlinda Lako, E M Gould, Rikke Due-Andersen, J N Mbanya, C Fiore, Takao Nakamura, Shield Jph., B Nadal, Lene Simonsen, Barry M. Brenner, D Fedak, J Chen, Laura E. Parton, Gao H-Y., John B. Buse, B Vialettes, M Y Guo, T Evers, Melanie J. Davies, Joan Soler, D Schmiegelt, Bárbara Angel, Hoe, B Parker, G Giovannitti, Ross Lawrenson, O Rigal, J Raastam, D S Kim, Björn Olde, Berggren P-O., Calum Sutherland, F Vittone, A Gauthey, A. M. Wagner, Paul Czernichow, Arturo Rosso, A Peter, J Hřebíček, V Martínek, B Jardin, A Fiorito, M V Trigo, S Bassan, N R Busciantella, C Turpini, G Seghieri, R Gelisio, K Nakanishi, D Pittasch, A Kamaratos, Irminger J-C., Monika Cahova, Y. Miyazaki, D V Coppini, Avierinos J-F., Erifili Hatziagelaki, S Schmauss, Richard G. Feltbower, Giancarlo Viberti, P G Steg, S Paulin, S M Marcovina, C. Marzari, Keld Fosgerau, S A Constantin, Adam Kretowski, K Yoshiuchi, K Cypryk, Geloneze, Jason L. Eriksen, Luis Garcia, L A Lavery, A Paroli, C A Ellery, M Morales de Teresa, Martin Ridderstråle, Riccardo C. Bonadonna, Solomon Tesfaye, N Gebeloglu, S Odenbach, A Baumgarten, Frank Schaper, K Dimitriou, F Costantino, O Basat, C A Mathis, V Lassmann-Vague, Kim D-J., J E Pessin, Shi Y-F., Michael Ristow, Kerstin Brismar, V Padilla, M Paganelli, Katinka Stoffels, A Caselli, R Cioni, G Nosso, C Conde, J Foley, M Tsuchiya, I Naumenkova, J M Pou, D Holmes, Richard J MacIsaac, M J Davies, G Jenkins, F Lavalle-Gonzalez, Daphne Owens, E Gibson, Richard E. Gilbert, Foster Avm., Sieradzki J, M W Davis, S Lahiry, James Mason, S Di Silvestre, Ken Walder, B Sporleder, B P Nixon, S Murao, Claus Thamer, V Kren, M A Buyukbese, B Burwinkel, M L Bigelow, C Bellin, P Mayr, J C Beer, Kim K-S., Willy Malaisse, A Ojeda, M Macugowska, A Varró, E Hammer, A R Baker, Alan W. Stitt, Rayaz A. Malik, H A Keizer, A Poscia, V Suri, K Kusterer, Allan D. Struthers, Martin J. Hessner, L A Anderson, Nigel Irwin, J S Christiansen, H V Schaff, D Hancock, L Nielsen, J J Mukherjee, M Essenpreis, C R Stephenson, D Betoulle, T Shibata, L Blonde, S O'Neil, T Hrachovinova, B Mirkiewicz-Sieradzka, G M Valorani, S Jahan, P Luzniak, Stephanie Halford, B Young, E Zabala, P Jousilahti, Hubert Vidal, P Kowey, G Hawthorne, A Zalewski, D Cokkinos, J Maroni, S Drewelow, Y Gao, Maria Paula Macedo, Wendy Dean, Janusz Blasiak, Delporte M-Ll., J Doupis, S Marcu, G Su, D Christakidis, Sabine Sewing, P Pánczél, H Matsumoto, K Rickenbach, A Calì, Giuseppe Derosa, A Linke, H Piperidou, Y Miura, B Kocher, D Nelson, Jo Y-Y., Päivi J. Miettinen, D Leontsini, M Prasek, A R Jones-Leone, H Ahn, R Alemzadeh, Yoshitomo Oka, Anna Solini, Fernanda Ortis, Neville Owen, Simona Cernea, Maciej Pawłowski, Sherry Martin, J L Selam, T Tulokas, K Lammi, Rolland J-F., Stephen Thomas, R.T. de Jongh, C Diehm, S Altimir, E. Manzato, W Szymczak, Michael Khan, S Lally, S Aycheh, I Stengele, Kim S-I., Zbigniew Szybiński, Carol Bower, Koichi Kato, I Evangelista, Eveline Eschwège, S Fujimoto, J Born, Elizabeth J. Mayer-Davis, O Schnell, Y Zhang, C Jørgensen, Lorenzo Piemonti, P Pithova, M Shirai, B. Kilhovd, M Dzabic, A.D. Hughes, Denis Raccah, P Berto, K Nizheradze, Tiinamaija Tuomi, Thomas Nyström, J A Shu, J Ostman, E Cicconetti, Helen E. Thomas, Margareta Svensson, P Vautrin, Andreas Fritsche, Lawrence Rosenberg, K Stoschitzky, M Yamakoshi, B Pandey, Kazuaki Nagashima, N Pound, W Srikusalanukul, D D Sandeman, L Wu, M C Stapperfend, P Saxena, SE Jones, C Colombo, C Caccioppoli, A K Keenan, P Piatkiewicz, H Frobøse, H-Erich Wichmann, J Marquez, C A Maloney, F Stasini, Elena Matteucci, J Arezzo, M Dalfrà, Maria Aisporna, M Nastoll, M Germán, M Riddle, Munehide Matsuhisa, Alessandro Sartorio, Henrik Toft Sørensen, Lars Rydén, I Panagiotou, M Fisher, J P Yeo, M C Riddle, K Anthony, Patrizia Ippolita Patera, T Bobkiewicz-Kozłowska, A Gasiorowska, M Artwohl, Kim K-W., Lutz Heinemann, P V Voss, A Tsuchida, N Ueda, Huriya Beyan, Joachim Rosenbauer, M Sultana, N I Gorbenko, B B Rønn, J Bělobrádková, Michael Haap, J Després, K Cooper, C Tzioras, J Goodwin, J A Myers, Eriksson A-K., M Sahilli, H Sasaki, D Grassetti, S Nencioni, Suzuki J-Y., F Wang, Erica L. Fletcher, H Chen, P Augstein, W J Valentine, Burkhard Göke, Damien Jolley, K Raun, A Seftel, K Okumura, N Follak, A Risse, M Stolinski, Vineet M. Arora, L Vaur, Steven Patterson, T. Heise, Rossi Mce., L. Quarré, D Dorigo, K P Bouter, H Serghides, M. Matsuda, Astrup Av, R Cramb, S Chipchase, Andrzej Lewiński, R Wadwa, C Friedrich, S Giordanetti, Joan Vendrell, Souvik Das, D McGechie, E Locatelli, E Sossidou, D Li, Meinardi, G Thalhammer, Jay S. Skyler, C J Muller, Ulla Feldt-Rasmussen, Susan M. Ring, Richard R. Rubin, S Pramming, Attila Brehm, D Klomp, C Plachot, E Santeusanio, F Roquet, A Naassan, B Pini, Patricia B. Carroll, Maura Pettiti, David S. Rowlands, Jandeleit-Dahm Kam., Timothy M. Frayling, A. K. Sjølie, A. de la Peña, M Franciosi, P A Torjesen, Jonathan C. Levy, S Caruso, B M Sreckovic, S Kim, L Arnaldi, H. B. Holt, M. Parkkonen, Francesco Dotta, M Diamant, H Hilden, A Manginas, N Tsokos, Davis, Barbara Leibiger, M Vaxillaire, V Deschamps, S Hernandez Campos, M Benchimol, Meftun Ahmed, S J Murdoch, Z V Zabarovskaya, Christine Waterman, T Werner, L Brunerova, D Coca-Robinot, D Pejkovic, Jesper Lau, Andreas Melidonis, R A Afonso, V Bronte, W Kotowa, C Broca, Orian S. Shirihai, Stehouwer Cda., Y Nishi, S Wanyonyi, R Fabregate, P A Khanam, S Nepal, Aimin Xu, Jan S. Ulbrecht, S M Ilic, H Hattori, A Panadero Moya, Pietro Castellino, Chiara Guglielmi, Masaru Sakurai, C Barrett, T Trüb, Christine Darwin, S Gross, Carmine Gazzaruso, J Coulaud, L Carbillon, Choi N-H., Anna C. Calkin, U Besenfelder, W Horn, K P Zak, S Nordman, L Zajdenverg, Y Sunaga, G A Spinas, P M Whitty, Kentaro Ohtoshi, Daniela Gasperikova, T Rinaldi, M R Nangle, Vincenzo Positano, C Lasseur, Paul Marsden, M Cinteza, Jeannet Lauenborg, M Párrizas, B Arslan, D Oakley, N S Mason, F Lauster, A B Lowenfels, A H van den Meiracker, M De Smet, P Politakis, Martin Tfj., M Watanabe, Gianna Toffolo, M Kimura, Sudhesh Kumar, A Petrov, G A Raciti, A. M. Umpleby, T Pervin, Maciej T. Małecki, E Tuomilehto-Wolf, Elisabeth R. Mathiesen, R Bonfante, R Gerona, L F Zang, T Sundsten, Mogens Kruhøffer, Johanne Tremblay, Naoto Katakami, L E Foster, Jorge Ferrer, D M Yellon, G Macdonell, T Appl, Levendal R-A., Arany Ejr., B Glisic, R Lestrade, M Dolci, F Pellegrini, K B Rooney, T Ishikawa, H Mayaudon, G Freckmann, V Asnaghi, N Rajkovic, Markus Tiedge, J Marniemi, Jian Peng, D Treacher, P. Z. Zimmet, V Jewhurst, H S Chaudhury, Magnus Møller, E Mathiesen, S Triscornia, Michael Stumvoll, Dirk Wedekind, T Todo, N Schifino, Jacek Kasznicki, C McHorney, Am Sironi, V Patel, N A Abdella, K Ohno, Karin Jandeleit-Dahm, Rafn Benediktsson, K Sztefko, D Yin, Michael R. Christie, J Hill, Simi Ahmed, A Behar, Borys J-M., Don Johns, David G. Armstrong, B Hare, B Szepietowska, S Frojdo, B Meyer, H Hanaire-Broutin, R Reich, A T Ali, A A Dreval, A J Stears, Y Sui, V Mattoo, Wilding Jph., F Azizi, M A Heise, Dana Dabelea, Afshan Siddiq, A. P. Lambert, L Steen, Giuseppe Pugliese, Steen Andersen, F Salman, G Parnaud, Hahn J-U., R A Silvestre, B Idzior-Waluś, B Guy-Grand, Linda D. Voss, Peter G. Jones, E Konoue, G Mello, Vigdis Aas, Yoshifumi Suzuki, Allan Flyvbjerg, L Mogylnytska, J B Hansen, Finn Gustafsson, Jürgen Schrezenmeir, S Kondo, A Ruggiero, I Tarkun, Jan Kopecky, A Umehara, K J Wiefels, D Ogawa, M Austen, F Bataller, John Wahren, Birger Thorsteinsson, G. H. Tomkin, I Pogliaghi, Ahn C-W., M Ishizaki, I Peiró-Martinez, Webb D-L., Ketan Dhatariya, Akihisa Imagawa, Roberto Lupi, P Petit, F Fehse, Jason D. Cooper, Pfeiffer Afh., V Cunsolo, E E Agardh, R Nieuwland, F Ekram, Jensen Rbb., Jens Bülow, HU Häring, Quynh Ntt., D Kawamori, M Herná Alarcó, M Kolpe, Gianfranco Parati, N Labastie, U Mager, D Krenova, M Aragona, Wolffenbuttel Bhr., Pierre Maechler, B P Kovatchev, L Mordhorst, C Coghi, L Wassef, G Füst, Z M Lu, Ewan R. Pearson, D De Cesare, S V McLennan, K Mikoudi, Ali Naji, O Apostolou, A Roussin, J I San Pedro, L N Scherbacheva, A Baroni, McNamara Mrj., M Perez-Maraver, A P Shepelkevich, M Ehren, Alex Harper, C Merezak, M Morrissey, Leena Kinnunen, H Goto, P Maincent, Oluf Pedersen, R. R. Lyu, G Rizzo, V V Bogomolov, N Krasova, G M McGuire, Tina Parkner, A Timi, Johann Bauersachs, S Foussas, S A Schreiber, T Monauni, Schwarz Peh., Allenberg, J D Lee, S Dewan, Y G Zheng, D Carroll, E Sarti, C Wollheim, Anna Kaminski, C Menneila, P Bucher, Xu Jyu., Vincent Rigalleau, A Schöpfer, Hans Jörnvall, A Ben Drief, X Jeunemaitre, E Schuster, Chan Slf., S Bilgic, J Coverly, K Szafraniec, Stalenhoef Afh., H Bergert, David I. W. Phillips, J Maksimovic Pavlovic, Sergio E. Starkstein, E Chaim, T Lehmann-Lintz, P Salacone, Tim Armstrong, Ingrid Klöting, C M Frampton, Franco Cavalot, A.K.Azad Khan, H Rose, Marta Letizia Hribal, Jette Kolding Kristensen, H Gröbe, M Nishi, A Vanderplas, Howlett Hsc., L E Bowen, R Malik, A Wu, Charles C. Richardson, Y Li, P G McNally, Yoon K-H., A Baleydier, M J Murphy, P. M. Nilsson, U Lindblad, Sten Madsbad, T Bíró, Riitta Veijola, Charlotte Glümer, Assunta Pandolfi, Lydia Aguilar-Bryan, M Namba, C Franzen, S Lopatriello, David Russel Jones, S. Cellek, T Derezinski, Ronald P. Stolk, B Yermen, Marina Trento, Christine Feinle-Bisset, T S Futers, Ahn S-K., D Yue, R Nakamura, Shin Tsunekawa, Ortwin Naujok, Marina Vladimirovna Shestakova, Matthew Wintle, M P Guarino, Giovanni Camussi, B Persson, M Brahimi, Raffaella Buzzetti, H Hendrickx, H Schuster, Anthony J. Brookes, N K Hoa, A Ianni Palarchio, T Marte, N H Redemann, M Pufal, Roya Babaei-Jadidi, C Glüimer, Susanne J. Szabo, G Zuodar, Laura Calvillo, M Homering, K Stegner, L Min, Y Haider, S Evangelista, N Soydan, Y Yerushalmy, Z Karimi Anderesi, A Bernjak, Laine A-P., A E Udovichenko, Eva Corpeleijn, A Rieger, Tahseen A Chowdhury, D Schmid, Krystyna Matyka, O V Ivanova, G Ciampittiello, P Vague, I Schmoelzer, Groop P-H., J Weidenhammer, Luis Arnes, A Khoruzhenko, Jelena Skibova, W Jefferson, M Catala, J K Wilson, G Dunseath, A D Tselepis, S. Leotta, A. Sämann, R A Gerber, T Busila, P E Fraser, William J. Jeffcoate, J Pariès, K Huoponen, Anne Jörns, G Shanmugam, A Tsiavou, S Yoshida, Kim M-J., Annapaula Giulietti, S Paillasson, K Tsuchiya, Divyen K Shah, P Saar, S S Juarez, Stefanie Maxion-Bergemann, J Briody, V Schmitz, C M Pena, J Fernádez-Real, S Naruse, M Kalis, A P Klimenko, X H Chen, H.H. Lervang, G Bock, Mirja Tiikkainen, J Potockova, N Pekcanli, George Dragicevic, Timothy M. Rose, David C. Goff, H Komori, V Vasseur-Delannoy, S Hanley, P Hajos, C W Ahn, Matsuoka T-A., J Burns, Petar M. Seferovic, Yuki Kita, K Lyons, K Kohri, Eleftheria Zeggini, Y Ding, G Belcher, Steven V. Edelman, N Dinççaǧ, Christopher J. Rhodes, Manders Rjf., S Giveon, Dario Iafusco, L Li, M C Ribaudo, Kang S-K., Laurie J. Goodyear, L Martinez, C Vermigli, H Dabire, R Raymond, J de Haan, Christopher J. Groves, Å Norberg, H Jahr, M Gloster, Christopher D. Byrne, R Nagase, M Gorska, S Jinagouda, Marcin Baranowski, J M Bruun, L F Fan, Marco Bugliani, Ferdinando Nicoletti, S Born, T Milicic, C Haug, A Imbroinise, Rafael Carmena, G Gedulin, Benoit R. Gauthier, M Ptak, Schweitzer M-A., A Kayserilioǧlu, Rory J. McCrimmon, Ludmila Kazdova, D Pittrow, M Unal, L G Hunsicker, B Komsuoglu, E V Titovich, N L Petrova, M F Saad, T Lindström, D Koev, G Pigas, Pamela Phillips, Timo Otonkoski, S Kanhasura, Ignacio Conget, L Forga, B Rokeya, K Naraine, M Kuroda, F W Hanna, N Hancu, O E Voronko, A Urrutia, E Krusinova, K Stenlof, G. Philippou, W E Brady, Shlomo Sasson, I Cuccuru, S Welte, Md. Shahidul Islam, P Burian, S Creely, B Reinsen, Seema Garg, R Froguel, S Mathi, Myriam Nenquin, R S Crow, L Wogensen, J Brumberg, M Saito, E Hak, C Caravaggi, B Veldman, R E Gregg, A Swaminathan, S Allgauer, F Whitehouse, J Saban-Ruiz, S Rössner, A B Lewandowska, Toshinari Takamura, Elaine M. Dennison, Eugenia Carvalho, Rafael Simó, F Gigli, Chiasson J-L., H Weiss, E Jaeckel, T Krarup Hansen, F Bonnet, J Wu, L A Atramentova, F Murray, Flemming Pociot, A Arne, C. Valadas, F Boomsma, Marketa Sjögren, C Richart, Stefan Schreiber, M M Musri, M Dworacka, E Zakja, Peter Båvenholm, R Gelfand, Steven W. J. Lamberts, Temel Yilmaz, F Péan, K Rave, M Hirata, C Helbig, Y Kido, M Sumarac-Dumanovic, Emma Bingham, N Saadat, L Strindberg, R G Brodows, J Rihl, N C Unwin, Peter Watt, P. Van Rooy, Alexander V. Chibalin, M Michelini, Chantal Mathieu, Samy Hadjadj, W M Sallas, E Schroeder, E Woźniakiewicz, U Golbach, Jeong I-K., M Nam, M Thompson, E Berrone, Leena Ryysy, S Matsuno, G R Fulcher, Jan Schulze, Rachele Berria, Abdol-Reza Esteghamati, Claire Pentecost, D Begic, D Bailbé, J Seo, A Caduff, M Hompesch, E Nishimura, Soroku Yagihashi, Przemysława Jarosz-Chobot, A L Harte, M. E. Trujillo, Dreyfus J-F., G Golor, O Serri, George A. Werther, S Pahler, M Traversa, A. Jotic, I Seljeflot, Renata Krupa, K Irjala, M P Manns, V Sasseville, M R Yun, I Tauveron, Moira Harrison, C Müller-Brandes, Jan Škrha, L Javashvili, C Giusti, Jørgen Rungby, R M Segura, Oh Y-S., P Cavallo Perin, A Piazza, Fumihiko Sakakibara, F Caricato, K Manolopoulos, H. Aladdin, Elena Delgado, C Negut, R Hougaard, H Feldmeier, Francesca Cannata, B Mylari, C Kloos, Xia Li, A Turco, P Thieblot, J Lee, K Koczwara, Gan Huang, I M Briaud, L. Williams, J Ibáñez, Wing-Yee So, Joachim Størling, Kamadjeu Rkk., Sarah J. Bailey, J M González-Posada, M Brändie, M Adiseshiah, N Boschetti, K Tsukiyama, R Iwasa, Naoko Tajima, K K Seah, K Gorbenko, B Saha, Bettina Fischer, M Boronat, Y Kaneko, P K Jaiveer, T Østergård, S Pye, J Rosada, M Fazia, S Duran, Jonas Lindström, Muller Lma., Lee H-C., B Wilke, U Wohlrab, Y López, Philip Hougaard, H B Mortensen, G Riccardi, I Dedov, S Mauri, P G Matthews, D Holt, C Schöfl, N D Hancu, P Tong, Frank Döring, Michael Edmonds, Krystyna Wyka, R Citarrella, M J Mohler, Fabio Vistoli, J Gabaldon, T Gambling, T Barnera, Patrick Gilon, F Hadj Brahim, T M Kuchmerovska, Joachim Spranger, G Collier, Małgorzata Szelachowska, V Hwa, J Herwig, Asish K. Saha, Antje Wienbergen, P Merkouris, V R Driver, G Pellegrini, C Tusek, D Kuhl, J Salvador-Rodríguez, A Rivero, Af Björkesten C-G., L P Aiello, Ángela M. Valverde, A. Sola-Gazagnes, M Lenz, N Duffy, T. Charniauskaya, H Vavrinkova, B B Dokken, N García-Hernandez, M. C. Matteoli, W Neuhuber, B Gutt, Haiyan Wang, C De Tullio, Nikolaos Tentolouris, Susan E. Ozanne, A El-Ouaghlidi, R A Blacken, P K Marsden, S Saragoni, E Fernández, P Thams, Yukio Tanizawa, Cora Weigert, A Bajo-Martinez, A Icks, Yu Liu, Jan Erik Henriksen, J Lupón, C Chrysohoou, C Y Pan, M Enslen, Carsten F. Gotfredsen, S Paxian, C Sert, B Lescrauwaet, Nikolaos Karachalias, Harald Staiger, Soon Dkw., S Mandica, Arild C. Rustan, T Kokko, Luigi Gnudi, L Mantione, Y Mitchel, K Takebayashi, K Lindström, A Akhter, I Calota, Z A Leshchenko, R Henry, E Hagström-Toft, J A Sloniger, C Gredal, Palmer Cna., C Remade, Marion Marchand, S Liew, F Oriente, R Roesen, Ekaterine Bakhtadze, J Bodalski, Věra Lánská, U Baicchi, Terezie Pelikanova, Aniko Varadi, Trudy J. Smith, R Vettermann, Daniel Pipeleers, Becker Rha., S Speier, Saeger H-D., A Tedeschi, Peter J. Grant, W A Scherbaum, R Scardapane, C Arntz, L J Kerr-Bayles, V Poltorack, Sol E-R., G Deniz, Kasper Rossing, Scott J. Jacober, D Lucchesi, Kees J. Gorter, Shin J-S., F Bifari, Ravi Retnakaran, P C Tsiotra, Anna Möllsten, K Mironczuk, A Erdei, Gerry Melino, S G Kauschke, E Stenninger, A Morsanutto, Carmen Fajardo, A. Khan, M S Rasmussen, A Villena, C Ilic, G Gruden, S Uhles, M I Freed, I K Temple, Marco Giorgio, Z Radikova, M Lou, Theodora Temelkova-Kurktschiev, Sorin Ioacara, Patrick A. Ott, Christine Longuet, E Baldassari, Ian Chapman, Cristian Guja, S Seber, K Lundin, Juretschke H-P., A Kanatsuka, Schumicki D-M., Boris Mankovsky, E Liva, Johan Wadén, G Steil, P Chauveau, K Schafer, V Borzì, A S Andersen, D P Mikhailidis, L Groop, Hans J. Arnqvist, M Salvadorini, H. J. Bodansky, Johnny Ludvigsson, A De Paoli, A de Prado, P Olesen, P Syrovatka, V V Klimontov, E Rodriguez, Arthur S. Leon, Alberti Gkm., A Opel, S Kokkoris, S B Hong, Philippe Courtois, L Haque, Maria Sörhede Winzell, M C Beauvois, A Szypowska, D Yu, M Gutniak, D Petzinna, B Isomaa, K S Prickett, Maria Felice Brizzi, Pavel Hamet, P J Hammond, K. F. Michelmore, Yumie Takeshita, N Hariharan, Corrado M. Cilio, G Pogatsa, W G Jerome, E Bartley, K Schlembacher, G Blohmó, Guy A. Rutter, Kyung Mook Choi, S. C Tamer, Felix K. Assah, K A Jandeleit-Dahm, M Chan, H Darius, Jørgen F. P. Wojtaszewski, A Papazisi, M Amaya, A Knopff, M Tadayyon, I J Kim, W Russ, T Myrnäs, M. Tryon, S Poonsatha, Noel Cameron, Kim M-H., Alejandra Tomas, F Homo-Dekarche, G. Di Cianni, M Stotzka, C Solimine, Mikhail Borisovich Antsiferov, H Naserke, M Bianchi-Biscay, J I Lara, Moon C-K., Alain Ktorza, Alison N. Jeffery, V Lilla, Eun Seok Kang, Hanley Ajg., J Widder, R Ratner, C Goretti, P J Weston, J Perkins, V Rasmussen, M Evans, T M Gibson, A Jaffe, S I Chisalita, C Owman, L Hiltunen, E Kakishita, C M Mack, H C Potter, M Femerling, M Desai, M Soinio, K Yang, Patricia L. Brubaker, M Meyer, V Dy, J Berden, R Komers, Milos Adamec, R Petzoldt, Alan G. Robinson, R Stevens, A Doi, A Leunda, Eduard Montanya, Alessandra K Cardozo, N Kraenkel, Claudio Cobelli, U A Mueller, S Yamashiro, B R Gedulin, G Francisco, J Dennenmoser, Lesch K-P., Martin G. Bischof, M Ichita, C Fernandes, Jochen Hampe, S Kern, D Kelly, E Zeender, P Perna, J D Best, A C Calkin, Vivian Fonseca, J Prestle, D G Parkes, Satish K. Garg, T Burrell, B M Fischer, D Kruger, J S Skinner, Lin T-M., Jozef Ukropec, Maria Jeziorska, K Arii, David D. D’Alessio, M B Gomes, L Quandt, I Fragaki, M C Brindisi, A Gladkih, E Kitsou, S Di Cola, T Iwasaki, Peter Diem, T Lakka, V V Popova, G Lee, Hannah J. Welters, K Bonomo, Gavin Kelsey, Y Yerushalmi, A. H. Barnett, H. von Boehmer, K Blomberg, B Haag, M C Preiti, V Sanchez-Margalet, Fowelin Jhr., Y Bernard, M Chalkiadaki, E Grandi, R M Gow, V Schippmann, E. A. M. Gale, R Schiel, R Iwai, O Olari, A Braun, D Koziarska, Bernhard Ludvik, Lee H-W., W P Battisti, N Oliver, M Pankop, H Vertigan, M Pibernik-Okanovic, D Gianneli, J Oh, R Giorgino, M Ballmann, Olle Korsgren, M Pantaleoni, S Zavarella, Göran Sundkvist, Hans Stenlund, Harleah G. Buck, David J. Glass, Morrissey, I Uchimura, M Pugniere, R E Warren, M Mikkola, Baradez M-O., M Weck, C Häuser, D Šrámková, D Voelkel, R Prager, Y L He, M Cornes, O K Vikulova, E Evdemon, Peter R. Cavanagh, Allen Taylor, M Balabolkin, G Schreier, E Stern, J Lips, V Serban, G Sparacino, Roser Casamitjana, Aine McKillop, I Groza, E Bernal, Kathleen M Gillespie, T Ledet, A Garzaniti, F Hawkins, K M Tushaus, C Renaudin, Christina Maier, A Dormi, A Ubertalli, Inge Tetens, M Ostojic, E Pierre-Justin, A Bhushan, E Ur, L I Jeltova, Tilo Moede, E Tibiriça, Zoran Gucev, Knoch K-P., G Pizzolanti, A M Şengül, T P Degenhardt, Cristina Lencioni, M Fitchet, E Santini, E Devangelio, C Panaite, Y I Karachentsev, S B Solerte, Christos Manes, M Lipka, C H Teng, P Mrak, G Fegan, R C Milton, M Negrean, Astrid Plamboeck, L Patti, M Houk, Ritva Kauppinen-Mäkelin, Christoph F Ebenbichler, O Sysoyeva, Frantisek Saudek, H Wysocki, Robert A. Rizza, J Altirriba, Bjørn Richelsen, L. Lam, Rémy Burcelin, A Antsaklis, G Galimberti, R. de Vries, A Lewin, Marcia A. Testa, Lee B-C., M Krauth, A Fonollosa, Marco Cappa, L Rieger, Edoardo Mannucci, André Herchuelz, H Corominola, I Gangat, G Rábago, S Dalla Noce, L Kunselman, J Diehl, M Nattrass, M Kaiser, R Kawamori, E Istoc, Á Pintér, D G Maggs, T Aoki, Csaba Szabó, B Oguzhan, Roberto Ferrari, D M Schumann, Yang Y-W., Hideaki Kaneto, Q Chai, E Blase, Katarzyna Wozniak, D Quijada, George Dailey, U Stier, M Skowronski, Thierry Berney, Adria Giacca, M Askenas, C Tikellis, T Zima, M Lufuma, P T Sawicki, M Dundua, Y Kitahara, M Winter, Janet Lutale, David E. Kelley, Alicia Acitores, Erion, Matthias Möhlig, S Dalal, Birgit Rami, Monster Tbm., Michael Horowitz, L A Leiter, Neil B. Ruderman, David R. Hadden, Mark Walker, I Garai, Michel Polak, A Somogyi, C G Walker, Claes-Göran Östenson, Ou H-C., Thomas Haak, G Kouri, W Pusch, J Fabrin, Robyn J. Tapp, E Zander, B Todorova, Peter Damm, Mine Yilmaz, Michel Pinget, Aila Rissanen, K Leppert, Darren J. Kelly, R B Zaid, A Bohbot, U Fennenkötter, Margot Umpleby, H Rodriguez-Rosas, R. Edwards, J Boavida, S Micheletti, E Bouskela, J Kreuder, N Mizutani, Pardo Icg., R Haberl, S Georgia, D Choi, Monika Lechleitner, R Guerrero, C G Bala, S Y Kim, R Oates, C Miele, E Witthaus, T Sakai, Albert Lecube, Anne Sofie Astrup, Teppo A-M., Margareta Norberg, G Dakovska, I Spanopoulos, P. Djordjevic, Nikolai Petrovsky, J M Fernández-Real, NanWei Tnw., Bilo Hjg., D L Lawlor, E J Henriksen, Anette-Gabriele Ziegler, A McDougall, L Wong, M G Choi, Connie S Karschimkus, M Zaramella, M Gallo, I. G. Lawrence, Viswanathan Mohan, L Valera, H V Silveira, C Pitsavos, Kasper Hermansen, Cloos Pac., K F Hanssen, Samuel W. Cushman, Juergen Eckel, R E Hamman, N Scheffler, C Lengyel, D Bakri, M Fukuda, P Rossetti, A Heerschap, Barbara A. Fielding, Choi Y-H., M Massi-Benedetti, Mykola Khalangot, F. Campi, W A Al Dahi, G Hu, Q Dang, J Ruzickova, A Lifshitz, L M Scheek, A Penfornis, S.C. Campbell, T S Filters, A T Shearer, A Morosanu, M Yngen, K Dezaki, C Damgé, Robert B. Wallace, Neil Portwood, M Henricsson, M Yazawa, J Yantha, G Tepohl, Christopher S. Wendel, Oliveira Jep., R Tracy, M Schindler, M Nabli, H Hosoda, Linda Boselli, B Kunselman, Mentink Cja., L Waselle, P Šamalíková, J Kirchheiner, S Sejil, D Beebe, James D. Otvos, J. J. Holst, J. B. Lopes de Faria, Marian Rewers, Kenneth Cusi, Geng Y-J., F Esfahanian, Francesco Giorgino, D. Freedenberg, R De Caterina, J Seufert, M N Kerstens, W Sturm, M Fujiyama, Konstantinos Makrilakis, A Novials, Lars Berglund, P Strange, W Shim, Clive J. Petry, Michelle M Jack, A E Panteleon, S Wiltshire, G Radulian, C Leperlier, N Téllez, O Sekine, M Karlén, Noël C. Barengo, Qing Qiao, Christian Benedict, C H Saely, M Yoneda, C Gonzalez-Villalpando, Sara Giunti, W Roth, S Wein, E Com, Martin J. Stevens, Giovanni Ghirlanda, Darin Acosta, J Hokanson, M Hauschild, L. A. Powell, Vondra K, Haering H-U., F Afifiyan, K Bendtzen, D M Todd, Marc Y. Donath, Arleta Rewers, Francesco Prisco, R Maeda, A B Kanstrup, M Prats, Y Toledano, Timothy W. Jones, Simon C. Potter, Per Løgstrup Poulsen, M Ligueros-Saylan, Mark L. Evans, Jarl S Torgerson, G Zerbini, L A Ivanova, E Ohmura, C. Kupich, K. Yasuda, J Leprince, A Alaveras, R Ruetter, Kevin C.R. Baynes, Harald Sourij, Y Aramaki, du Prel J-B., Józef Drzewoski, van den Ouweland Jmw., Jochen Seissler, Iain D. Wilkinson, Irina A. Bondar, Y R Yu, S Miclea, S Galatius, T. Havrdova, L Montoya, M Zeller, G C Jones, R B Amazonas, T K Guseva, A Davidescu, Stavros Bousboulas, A. Sandbaek, C Ito, H Taniguchi, M L Simoons, Lars Weinehall, H. Boeing, M A Tambascia, R Grempler, C Speed, A M Mkrtum'yan, A A Darekar, K Hu, Firth Rgr., I Östlund, S Kawazu, P Chitson, B Perry, Joel Dunn, D G Rouiller, K Wagner, Oleg Dyachok, Algis J. Vingrys, S Habu, Mariella Trovati, H Sobajima, Pierre Lecomte, Kim T-H., D Virsaladze, M Oprean, F Pullen, A Rußmann, G J Bruining, Martina Düfer, Wen Xu, Min Y-K., Norman E Cameron, Gianfranco Pagano, K Harley, M Su, J P Le Berre, Sian Ellard, S Howard, D Russell-Jones, Z Li, S Carpenter, E L Thomas, W Tang, Lee M-S., N Ubrich, M. M. McMahon, G Vassilikos, N Brossa, M S Joergensen, S Smith, A Vania, Y Laurent, S Basir, A Freudenthaler, Sally M. Marshall, D Niedermayer, V I Pankiv, J Mentel, S Pruna, J M Pou Torelló, Y Ito, G Chrysos, Werner Kramer, Hironori Yamasaki, L Bowman, F Palumbo, P Ruth, G Lankas, Z H Liao, D Park, W Otter, C Montrone, Sevasti Zervou, Jennifer L. Wilkinson-Berka, Bo Feldt-Rasmussen, I Banu, Paolo Sbraccia, Bani Mukhopadhyay, Mark E. Cooper, M Kidron, Pål R. Njølstad, A M Jonsdottir, M R Burge, G Valpiani, Yutaka Oiso, David J. Hill, T Koch, J Park, A J Plaschke, M P Pye, A Totonelli, S Caronna, B Cremonesi, C Müller, K Tarhzaoui, Valentina Marchetti, M Rodier, Moshe Hod, C N Dang, Trevor A. Howlett, S J Thomas, C Penny, A. de Leiva, Gerald Vervoort, Ghislaine Fontés, Agnieszka Szadkowska, I Al-Zakwani, A Manari, M Eigenthaler, A. Björklund, K Nabe, Mohammad Abdur Rashid, Philips J-C., K Rebrin, Stefan Müller, Claus Thorn Ekstrøm, A A Papageorgiou, L Franco, Paul Hjemdahl, Martine Laville, Flemming S Nielsen, A I Vinik, P Perelli Cippo, Mikael Lehtihet, M Zairis, H Takahashi, M Pietryga, M Kameyama, Jens Knudsen, W W Lautt, Z Rušavý, G Milic, E Pedersen, U Krause, B Balletshofer, J Reviriego, A Scatena, H C Chen, V Gottschall, Alberto Piaggesi, J Gebbie, Maurizio Galderisi, K Nikkiä, A Blayo, D S Fosmark, DL Eizirik, K Busch, Francesco Beguinot, F Capani, A Carrillo, L Nährlich, Thomas Høi-Hansen, Bernard Charbonnel, Edith Schober, Ananda Basu, Deborah J. Smyth, Gerd Plewe, S Vahsen, Claire Levy-Marchal, B S Hansen, V Holtman, S Roche, C Whiteside, A E Fowler, K Helleberg, M Gerl, G Jerums, L Menditto, G Dell'Antonio, A Miles, E Kahan, M Kaibara, V A Serhiyenko, Cees J. Tack, M Shamkhalova, T Linn, R. Koznarova, O Oliyarnyk, Regine Bergholdt, Margaret C. Cam, Matthew Knuiman, U Guiducci, Joanne E. Curran, V Qvisth, F Horkay, Brun J-M., J Jurado, Markku Saraheimo, S Kaltenbach, D D Yin, E Mukai, M Schlosser, Kilbane, K Kølendorf, Hsu Y-J., Steen Gammeltoft, M S Mizel, U Müller, J Bothner, H C Schønheyder, M Ho, I B Bauche, A Etemadi, R F Urdaneta, A Kocijančič, Kim K-R., P E Carey, Olov Rolandsson, S Bochnig, Takahisa Hirose, Baldomero González, Banga J-D., S Vol, R P Hill, F Velazquez, Kathryn Mitchell, S Bott, Z Ma, Richard E Gilbert, D. Mills, A K Gosby, Alison M. Thomas, D Alexander, W Tanaka, Klaus Badenhoop, N D Thuan, B Otto, Gisela Drews, Rui Duarte, S Cantaro, Boulton Ajm., Hélène Hanaire, A Gorski, L Prieto-Sanchez, M Shestakova, Xiaoning Fan, M Higa, J Gurushankar, T Kunitou, D D Trifunovic-Zamaklar, J Nourooz-Zadeh, T F Ørntoft, G Doronzo, P Levéen, B Geloneze, C Fotino, D W Quinn, A Wojciechowska-Luźniak, G Mazzilli, Kook Hwan Kim, M Kaplar, L Dzneladze, Gregory J. Cooney, M Stahlhut, Frances L. Game, E J Bastyr, R Hiles, S. Mariz, T R Pieber, Howlett Hcs., J H Wilmore, Cha B-S., J M Brown, C Laue, Fiona M. Gribble, Susan E. Manley, D L Linemeyer, S G Ashwell, R Sabbah, Hisamitsu Ishihara, N Tronko, M Pohl, H Tindali, Lam Ksl., K Vollmer, I Nagaev, F. Gras, M Corfini, D Lyngsø, A M Sanigorski, Aldo Galluzzo, Alessandro Roberto Dodesini, E Shishko, H Moustgaard, S Piquer, O Tenberken, Ingrid Mühlhauser, A Sturk, Dianne L. Wingate, C Albala, Marie Degerblad, A Kubaszek, Gary W. Cline, J F Markman, J Louw, Y A Redkin, J E Shaw, Gaetano M. De Ferrari, R M Budzinski, I A Snegurakaya, P Kühnen, D Mustapic, Bo Ahrén, C Laflor, Eva Fisher, A Semplicini, C Pandolfo, Myriam Khaldi, K Mattila, Stella Pelengaris, Olga Kordonouri, M Nagao, P I Mansell, K Rduch, R Fahey, R Filipczak, M Suetsugu, J C Vitoria, J Baumert, J Stewart, R S Bonser, Jean Tichet, Christer Andersson, A Şengül, McCuaig, Zorenc Ahg., Xiuqing Guo, H Jordan, K Bieback, Daniela Dietze-Schroeder, J Shin, S Ohga, J Lademann, K C Turner, I V Shutichina, M. Shamkhalova, K Rowley, Rosario Rizzuto, Saraheimo, G. da Silva Xavier, Doss W. Neal, K Akram, H Virtamo, E Dios, K Begum, A Pfuetzner, Tsvetalina Tankova, S Katayama, Christoph Otto, Philip J. Barter, K Zitouni, R Madonna, S Söderberg, S Diaz-Troya, Leszek Czupryniak, S Dietz, P Luźniak, K S Nair, Mark A. Myers, L L Want, S Shaikh, Wolfgang Rathmann, E Wozniakiewicz, L Jönsson, Pernille Poulsen, D F Orr, A B Hauber, F Kelly, Carlo Maria Rotella, J V Costa, Elaine Vieira, E Grodzinsky, Lilianna Majkowska, E Draeger, S Näf, Philip Clarke, S Akter, A Bagust, A Vassibosis, E Lourida, P Chase, G Mardarowicz, Carlo Ricci, A Ugalde-Canitrot, A Wutte, R Streicher, P Ebeling, Taishan Zheng, Marcus Korn, K Summers, Lennarth Nyström, Y Kaburagi, T Furuta, S Freeman, D Skoutas, A A Serhiyenko, K Tryfinopoulou, I. P. Gray, Peter Bjerregaard, R H Elder, M Hosokawa, Marcela Brissova, Kent D. Taylor, R. Da Ros, Carolyn F. Deacon, Andrew D. Morris, N Aydin, Alicia J. Jenkins, L M Serhiyenko, M Sjöstrand, M A Sayeed, A Ardelean, Rolf Holle, I Broom, Giuseppina Imperatore, Massimo Federici, W Sajid, C Bradley, C V Phenekos, W Leonhardt, L Bahia, Veitenhansl, M, Stegner, K, Hierl, F, Dieterle, C, Feldmeier, H, Gutt, B, Landgraf, R, Garrow, A, Vileikyte, L, Findlow, A, Waterman, C, Boulton, A, Shankhdhar, K, Shankhdhar, L, Shankhdhar, U, Petrova, N, Foster, A, Edmonds, M, Ferraresi, R, Caravaggi, C, De Giglio, R, Cavaiani, P, Pogliaghi, I, Sommariva, E, Katz, I, Harlan, A, Miranda palma, B, Prieto sanchez, L, Armstrong, D, Bowker, J, Mizel, M, Cernea, S, Wohlgelernter, J, Kidron, M, Modi, P, Raz, I, Arbit, E, Nosek, L, Kapitza, C, Beckett, P, Gelfand, R, Goldberg, M, Heise, T, Testa, M, Turner, R, Hayes, J, Scranton, R, Simonson, D, Yang, Y, Hsu, Y, Naujok, O, Francini, F, Jörns, A, Tiedge, M, Lenzen, S, Abdel wahab, Y, Marenah, L, Orr, D, Shaw, C, Flatt, P, Chokkalingam, K, Mansell, P, Clausen, P, Ekbom, P, Damm, P, Feldt rasmussen, U, Nielsen, B, Mathiesen, E, Feldt rasmussen, B, Dewan, S, Da Silva, N, Ternan, P, Leong, K, Wilding, J, Asatiani, N, Kurashvili, R, Dundua, M, Shelestova, E, Pagava, K, Ramazashvili, M, Hod, M, Smirnov, S, Petersen, J, Justesen, T, Ringholm Nielsen, L, Müller, C, Højlund, K, Wensaas, A, Kase, E, Aas, V, Rustan, A, Thoresen, G, Levin, K, Beck nielsen, H, Gaster, M, Im, S, Kang, S, Kim, S, Ahn, Y, Lihn, A, Schmoll, D, Werner, T, Kienitz, A, Meyer, M, Barthel, A, Ailett, F, Sutherland, C, Walther, R, Grempler, R, Sasson, S, Reich, R, Tenenbaum, T, Alpert, E, Anfossi, G, Russo, I, Traversa, M, Massucco, P, Mattiello, L, Doronzo, G, Trovati, M, Lally, S, Tan, C, Owens, D, Tomkin, G, Porchay, I, Péan, F, Bellili, N, Betoulle, D, Balkau, B, Tichet, J, Marre, M, Fumeron, F, Chatellier, G, Alhenc gelas, F, Nichols, G, Brown, J, Hayes, R, Bowman, L, Drexel, H, Saely, C, Marte, T, Benzer, W, Langer, P, Hoefle, G, Moll, W, Aczel, S, Karagiannis, E, Lübben, G, Urquhart, R, Edwards, G, Bruce, S, Howlett, H, Cugnardey, N, Turner, K, Park, J, Fiedorek, F, Avogaro, A, Gallo, A, Pinton, P, Rizzuto, R, Murphy, E, Ceolotto, G, Caterson, I, Guy grand, B, Hill, J, Barone, M, Aiello, A, Allochis, G, Borzì, V, Cannatà, F, Caronna, S, D'Avanzo, A, Elli, R, Formoso, G, Paroli, A, Scardapane, R, Sorichetti, P, Tatti, P, Viviani, G, Santeusanio, F, Manzella, D, Grella, R, Abbatecola, A, Paolisso, G, Søndergaard, L, Monster, T, Johnsen, S, Olsen, M, Mclaughlin, J, Sørensen, H, Lervang, H, Rungby, J, Lyssenko, V, Fredriksson, J, Almgren, P, Anevski, D, Orho melander, M, Sjögren, M, Tuomi, T, Groop, L, Jaziri, R, Aubert, R, Tuomilehto, J, Hu, G, Jousilahti, P, Peltonen, M, Lindstrom, J, Laina, A, Alevizaki, M, Philippou, G, Souvatzoglou, A, Anastasiou, E, Alba, S, Metcalf, B, Voss, L, Jeffery, A, Wilkin, T, Glüimer, C, Colagiuri, S, Vistisen, D, Borch johnsen, K, Haynes, A, Bower, C, Bulsara, M, Jones, T, Davis, E, Mortensen, H, Hougaard, P, Holl, R, Swift, P, Pociot, F, Knip, M, Hansen, L, Szadkowska, A, Pietrzak, I, Zmysłowska, A, Wyka, K, Bodalski, J, Swift, R, Hougaard, R, Gerstl, E, Engelsberger, I, Rabl, W, Rosenbauer, J, Gröbe, H, Hofer, S, Krause, U, Dabelea, D, Morgan, T, Pettitt, D, Dolan, L, Mayer davis, E, Pihoker, C, Hillier, T, Imperatore, G, Ruggiero, A, Hamman, R, Stylianou, A, Tentolouris, N, Perrea, D, Tselepis, A, Lourida, E, Kitsou, E, Katsilambros, N, Vedovato, M, Dodesini, A, Lepore, G, Tiengo, A, Trevisan, R, Penno, G, Miccoli, R, Pucci, L, Lucchesi, D, Bandinelli, S, Fotino, C, Triscornia, S, Baldassari, E, Del Prato, S, Reboldi, P, Santeusanio, E, Fuller, J, Langham, R, Gow, R, Zhang, Y, Kelly, D, Christensen, P, Parving, H, Gilbert, R, Chibalin, A, Zhong, Z, Kotova, O, Davidescu, A, Ehrén, I, Ekberg, K, Wahren, J, Wassef, L, Buckley, A, Rooney, K, Briody, J, Thompson, M, Ozanne, S, Thompson, C, Chamson reig, A, Summers, K, Arany, E, Hill, D, Solerte, S, Gazzaruso, C, Locatelli, E, Precerutti, S, Schifino, N, Ferrari, E, Fioravanti, M, Phenekos, C, Ginis, A, Fragaki, I, Chalkiadaki, M, Tzioras, C, Powell, L, Mcguire, G, Jewhurst, V, Trimble, E, Rasmussen, B, Vessby, B, Uusitupa, M, Berglund, L, Pedersen, E, Riccardi, G, Rivellese, A, Tapsell, L, Hermansen, K, Da Silva Xavier, G, Rutter, J, Rutter, G, Briaud, I, Lingohr, M, Dickson, L, Mccuaig, J, Lawrence, J, Rhodes, C, Wikstrom, J, Katzman, S, Shirihai, O, Yang, J, Deng, S, Wang, X, Hessner, M, Wu, J, Wong, R, Sukumvanich, S, Markman, J, Naji, A, Wolf, B, Gao, Z, Rubi, B, Del Arco, A, Satrústegui, J, Maechler, P, Del Guerra, S, Lupi, R, Bugliani, M, Sbrana, S, Torri, S, Boggi, U, Vistoli, F, Mosca, F, Marchetti, P, Rennings, A, Smits, P, Stewart, M, Tack, C, Li, L, Nyström, T, Gutniak, M, Ahrén, B, Holst, J, Sjöholm, Å, Gomes, M, Cailleaux, S, Tibiriça, E, Albertini, J, Chen, H, Mather, R, Valensi, P, Chisalita, S, Arnqvist, H, Kraenkel, N, Adams, V, Linke, A, Gielen, S, Schuler, G, Humbrecht, R, Cipollone, F, Iezzi, A, Fazia, M, Pini, B, Cucurullo, C, De Cesare, D, Schmidt, A, Mazurek, T, Zang, L, Mannion, J, Diehl, J, Martin, J, Martella, A, Zalewski, A, Shi, Y, Otter, W, Winter, M, Doering, W, Standi, E, Schnell, O, Kragelund, C, Køber, L, Faber, J, Hildebrandt, P, Steffensen, R, Pankowska, E, Szypowska, A, Lipka, M, Herwig, J, Scholl schilling, G, Böhles, H, Robertson, K, Schönle, E, Gucev, Z, Mordhorst, L, Tamer, S, Gall, M, Ludvigsson, J, Hoogma, R, Hammond, P, Gomis, R, Kerr, D, Bruttomesso, D, Bouter, P, Wiefels, K, De La Calle, H, Schweitzer, D, Pfohl, M, Torlone, E, Krinelke, L, Conget, I, Storms, F, Rodriguez, J, Leperlier, C, Davies, M, Peter, R, Luzio, S, Dunseath, G, Miles, A, Hare, B, Backx, K, Pauvaday, V, Caselli, A, Marfia, G, Battista, C, Veves, A, Spallone, V, Uccioli, L, Gonzalez, J, Peyrot, M, Rubin, R, Leventhal, H, Scheffler, N, Ulbrecht, J, Cavanagh, P, Perrin, N, Oglesby, A, Bastyr, E, Ziegler, D, Siekierka kleiser, E, Meyer, B, Schweers, M, Selvarajah, D, Wilkinson, I, Emery, C, Shaw, P, Griffiths, P, Tesfaye, S, Obrosova, I, Arezzo, J, Phillips, K, Gribble, F, Williams, L, Reimann, F, Iakoubov, R, Whiteside, C, Brubaker, P, Acitores, A, González, N, Sancho, V, Valverde, I, Villanueva peñacarrillo, M, Martín duce, A, Trigo, M, Arnés, L, Burkart, V, Ichino, N, Ohashi, A, Klein, B, Paxian, S, Schmid, R, Karlsen, A, Heding, P, Frobøse, H, Rønn, S, Kruhøffer, M, Ørntoft, T, Nerup, J, Mandrup poulsen, T, Billestrup, N, Cardozo, A, Ortis, F, Feng, Y, Rasschaert, J, Van Eylen, F, Storling, J, Herchuelz, A, Eizirik, D, Wang, H, Kouri, G, Wollheim, C, Ribaux, P, Hammar, E, Parnaud, G, Rouiller, D, Bosco, D, Halban, P, Midthjell, K, Carlsson, S, Grill, V, Lau, C, Færch, K, Glümer, C, Tetens, I, Jørgensen, T, Tillin, T, Forouhi, N, Mckeigue, P, Chaturvedi, N, Zethelius, B, Hales, C, Berne, C, Coleman, R, Stevens, R, Holman, R, Christensen, J, Sandbæk, A, Lauritzen, T, Irwin, N, Gault, V, Green, B, Harriott, P, O'Harte, F, Bouman, S, Ursø, B, Brand, C, Rolin, B, Ribel, U, Schäffer, L, Maggs, D, Ceriello, A, Frias, J, Wang, Y, Ruggles, J, Kolterman, O, Piconi, L, Weyer, C, Want, L, Ratner, R, Uwaifo, G, Thornberry, N, Eiermann, G, Kim, D, Lankas, G, Leiting, B, Li, Z, Lyons, K, Petrov, A, Sinha Roy, R, Woods, A, Woods, J, Zhang, B, Fisher, M, Moller, D, Weber, A, Dreyer, M, Bellin, C, Schmitz, V, Roesen, R, Nescheret, A, Bose, A, Mocanu, M, Carr, R, Yellon, D, Manolopoulos, K, Born, S, Wagner, A, Jeziorska, M, Ben Drief, A, Bashir, M, Tomlinson, D, Malik, R, Zeymer, U, Schwarzmaier d'assie, A, Petzinna, D, Chiasson, J, Stratton, I, Af Björkesten, C, Fagerudd, J, Rosengård bärlund, M, Forsblom, C, Pettersson fernholm, K, Waden, J, Saraheimo, M, Rönnback, M, Thorn, L, Groop, P, Mollsten, A, Svensson, M, Kockum, I, Rudberg, S, Brismar, K, Dahlquist, G, Hovind, P, Hansen, T, Tarnow, L, Thiel, S, Jensen, B, Flyvbjerg, A, Kankova, K, Hertlova, M, Krusova, D, Schwenke, S, Ott, J, Thom, S, Mistry, P, Sjolie, A, Larsen, B, Witt, N, Hughes, A, Samira, H, Lahiry, S, Howlader, S, Parveen, S, Azad Khan, A, Clarke, P, Gray, A, Phillips, L, Phillips, P, Chittleborough, C, Baldock, K, Taylor, A, Davis, W, Davis, T, Knuiman, M, Hendrie, D, Worthley, D, Nicolucci, A, Pellegrini, F, De Berardis, G, Franciosi, M, Belfiglio, M, Rossi, M, Sacco, M, Valentini, M, Richardson, C, Jones, P, Persaud, S, Hussain, K, Clark, A, Christie, M, Gniuli, D, Hribal, M, Accili, D, Khan, M, Zervou, S, Cheung, L, Abouna, S, Ifandi, V, Pelengaris, S, Luco, R, Ferrer, J, Ma, D, Shield, J, Dean, W, Leclerc, I, Knauf, C, Burcelin, R, Kelsey, G, Powers, A, Shostak, A, Ferrara, N, Poffenberger, G, Jerome, W, Brissova, M, Geloneze, S, Tambascia, M, Pareja, J, Chaim, E, Silveira, H, Geloneze, B, Ravikumar, B, Carey, P, Snaar, J, Dheelchand, D, Cook, D, Neely, D, Taylor, G, Morris, P, Taylor, R, Stears, A, Masding, M, Wootton, S, Sandeman, D, Klimes, I, Wein, S, Gasperikova, D, Ukropec, J, Wiernsperger, N, Sebokova, E, Manco, M, Mingrone, G, Granato, L, Greco, A, Nanni, G, Castagneto, M, Vidal, H, Calvani, M, Ferrannini, E, Alvarsson, M, Sundkvist, G, Lager, I, Henricsson, M, Berntorp, K, Fernqvist forbes, E, Steen, L, Örn, T, Shutler, S, Bianchi biscay, M, Rosenstock, J, Sugimoto, D, Strange, P, Stewart, J, Soltes Rak, E, Dailey, G, Kloos, C, Müller, U, Sämann, A, Femerling, M, Risse, A, Jecht, M, Haak, T, Garg, R, Lawrence, I, Akinsola, M, Mcnally, P, Garber, A, Kim, H, Draeger, E, Aydın, L, Şengül, A, Kürklü, A, Uçak, S, Basat, O, Seber, S, Altuntaş, Y, Jin, J, Yu, Y, Yu, H, Zhang, X, Mattoo, V, Eckland, D, Widel, M, Duran, S, Fajardo, C, Strand, J, Knight, D, Oakley, D, Tan, M, Sato, A, Nagao, M, Aki, N, Nakagami, T, Iwamoto, Y, Zhou, Z, Li, X, Huang, G, Yan, X, Yang, L, Peng, J, Wang, J, Tan, S, Tang, W, Fürnsinn, C, Brunmair, B, Wagner, L, Gras, F, Artwohl, M, Zierhut, B, Waldhäusl, W, Shine, B, Hopkins, D, Anand, V, Lim, E, Raval, U, Sharp, P, Corder, R, Lipkin, D, Lahiri, A, Bartnik, M, Rydén, L, Ferrari, R, Malmberg, K, Pyörälä, K, Simoons, M, Standl, E, Soler soler, J, Öhrvik, J, Bruce, D, Starkstein, S, Schauer, U, Astrup, A, Pietraszek, L, Nielsen, F, Rossing, P, Ali, S, Smidt, U, Yokoyama, H, Pavkov, M, Knowler, W, Bennett, P, Nelson, R, López alba, A, Morcillo, L, Caballero, A, Montoya, L, Jiménez, A, Maceira, B, Lewis, J, Ravid, M, Wajman, A, Tadgell, C, Remuzzi, G, Hunsicker, L, Wadén, J, Wessman, M, Taskinen, M, Pugliese, G, Amadio, L, Menini, S, Oddi, G, Ricci, C, Iacobini, C, Pricci, F, Sorcini, M, Pesce, C, Migliaccio, E, Giorgio, M, Pelicci, P, Di Mario, U, Lassila, M, Jandeleit dahm, K, Seah, K, Calkin, A, Allen, T, Cooper, M, Lopes De Faria, J, Cavakcanti, T, Silva, K, Ferrari, A, Cellek, S, Foxwell, N, Cotter, M, Cameron, N, Tennagels, N, Jordan, H, Stahl, P, Voss, M, Welte, S, Werner, U, Lehmann, R, Moeschel, K, Baumgartner, F, Oeckinghaus, A, Beck, A, Weigert, C, Hennige, A, Schleicher, E, Häring, H, Müssig, K, Staiger, H, Natalicchio, A, Laviola, L, De Tullio, C, Renna, L, Giorgino, R, Giorgino, F, Falasca, M, Maffucci, T, Park, D, Song, J, Lee, D, Lee, Y, Hariharan, N, Kunselman, L, Gu, L, Sasseville, V, Harrity, T, Cheng, P, Pratley, R, Schweizer, A, Mills, D, Ahren, B, Kim, T, Song, X, Van Poelje, P, Potter, S, Dang, Q, Fujitaki, J, Linemeyer, D, Landau, B, Erion, M, Pankop, M, Golay, A, Després, J, Sjöström, L, Lawlor, D, Legg, K, Ur, E, Houweling, S, Kleefstra, N, Meyboom de Jong, B, Bilo, H, Schlömer, G, Meyer, G, Kasper, J, Mühlhauser, I, Young, B, Taylor, J, Friede, T, Hollis, S, Mason, J, Long, A, Gambling, T, Pauline, L, Burns, E, New, J, Gibson, M, Betteridge, D, Leiter, L, Whitty, P, Eccles, M, Hawthorne, G, Grimshaw, J, Steen, I, Vanoli, A, Wood, L, Speed, C, Mcdowell, D, Rewers, M, Maahs, D, Wadwa, R, Eckel, R, Tracy, R, Pfützner, A, Strotmann, H, Schulze, J, Hohberg, C, Pahler, S, Forst, T, Ambery, P, Sydall, H, Cooper, C, Dennison, E, Sayer, A, Barker, D, Phillips, D, Lalic, N, Ostojic, M, Lalic, K, Zamaklar, M, Jotic, A, Ilic, M, Rajkovic, N, Lukic, L, Milicic, T, Vergès, B, Zeller, M, Steg, P, Beer, J, Brisard, C, Brindisi, M, Dentan, G, Laurent, Y, Janin manificat, L, Makki, H, Ravisy, J, Cottin, Y, Ajjan, R, Grant, P, Futers, T, Carter, A, Rasmussen, M, Bruun, J, Pedersen, S, Richelsen, B, Dietze schroeder, D, Sell, H, Koenen, M, Eckel, J, Delporte, M, Bauche, I, Brichard, S, Ait El Mkadem, S, Rezsohazy, R, Tsiotra, P, Tsigos, C, Gatsiou, C, Raptis, S, Walker, C, Bryson, J, Hancock, D, Takahashi, N, Hatakeyama, H, Kasai, H, Gauthier, B, Iezzi, M, Fukuda, M, Duhamel, D, Ravier, M, Düfer, M, Neye, Y, Krippeit drews, P, Sausbier, U, Arntz, C, Sausbier, M, Neuhuber, W, Ruth, P, Drews, G, Beauvois, M, Rolland, J, Jonas, J, Merezak, C, Henquin, J, Gilon, P, Jabin Gustafsson, A, Dzabic, M, Islam, M, Vaxillaire, M, Cheyssac, C, Dina, C, Vasseur delannoy, V, Leprêtre, F, Siddiq, A, Froguel, P, Neve, B, Fernandez zapico, M, Ashkenazi katalan, V, Urrutia, R, Melloul, D, Froguel, R, Poulsen, P, Wojtaszewski, J, Richter, E, Vaag, A, Granhall, C, Renström, E, Luthman, H, Isomaa, B, Gloyn, A, Edghill, E, Pearson, E, Mackay, D, Temple, I, Noyes, K, Freedenberg, D, Gillespie, K, Lambert, A, Gale, E, Ellard, S, Hattersley, A, Fanelli, C, Porcellati, F, Rossetti, P, Busciantella, N, Billi, C, Burrin, D, Bolli, G, Bingham, E, Dunn, J, Sutcliffe goulden, J, Marsden, P, Amiel, S, Davis, R, Kennedy martin, T, Peters, J, Wittrup jensen, K, Mcewan, P, Morrissey, M, Currie, C, Akram, K, Pedersen bjergaard, U, Thorsteinsson, B, Pibernik okanovic, M, Peros, K, Begic, D, Szabo, S, Metelko, Z, Vlaiculescu, M, Calota, I, Busila, T, Bruckner, I, Giannakopoulou, D, Lindner, H, Hrachovinova, T, Fejfarova, V, Csémy, L, Malcomson, J, Campbell, M, Pandolfi, A, Giardinelli, A, Di Tomo, P, Di Silvestre, S, Di Fulvio, P, Capani, F, Consoli, A, Roesen, P, Patruno, A, Grilli, A, Capani, R, Felaco, M, Boner, G, Mccarroll, K, Brenner, B, De Zeeuw, D, Kowey, P, Shahinfar, S, Crow, R, Iso, K, Kuboki, K, Tada, H, Yoshino, G, Schjoedt, K, Andersen, S, Distiller, L, Degenhardt, T, Szabo, J, Khalifah, R, Schotzinger, R, Achenbach, P, Knopff, A, Naserke, H, Ziegler, A, Bonifacio, E, Valera, L, Jardin, B, Roche, S, Lampasona, V, Pugniere, M, Roquet, F, Granier, C, Laune, D, Afifiyan, F, Cheung, R, Yantha, J, Jackowski, G, Dosch, H, Nakanishi, K, Kogawa, N, Komatsu, Y, Fontés, G, Imamura, T, Ilic, C, Puech, C, Ktorza, A, Bataille, D, Dalle, S, Fosgerau, K, Gelling, R, Nishimura, E, Andersen, B, Madsen, P, Lau, J, Streicher, R, Wagner, K, Vettermann, R, Potterat, O, Renard, E, Panteleon, A, Kolopp, M, Rebrin, K, Steil, G, Hariri, F, Darwin, C, Saad, M, Buckingham, B, Kunselman, B, Wong, L, Istoc, E, Leach, J, Purvis, R, Monfre, S, Fischer, J, Garg, S, Ahmann, A, Ruchti, T, Gandhi, G, Nuttall, G, Mullany, C, Schaff, H, Williams, B, Rizza, R, Mcmahon, M, Gates, G, Mentel, J, Smith, R, Crook, J, Hosszúfalusi, N, Vatay, Á, Palik, È, Füst, G, Karádi, I, Romics, L, Pánczél, P, Aurich, K, Voelker, U, Braun, A, Nguyen, L, Kriketos, A, Denver, G, Üceyler, N, Schütt, M, Lesch, K, Mössner, R, Sommer, C, Seda, O, Liska, F, Kazdova, L, Sedova, L, Krenova, D, Zima, T, Tremblay, J, Kren, V, Hamet, P, Klöting, N, Follak, N, Klöting, I, Dessapt, C, Dei Cas, A, Baradez, M, Hayward, A, Thomas, S, Viberti, G, Gnudi, L, Gale, C, Thallas, V, Thomas, M, Candido, R, Burns, W, Forbes, J, Shymanskyy, I, Kuchmerovska, T, Klimenko, A, Jaeckel, E, Manns, M, Von Boehmer, H, Hedrich, H, Téllez, N, Montolio, M, Estimes, E, Rodríguez mulero, S, Soler, J, Montanya, E, Liu, Y, Chen, J, Rowlands, D, Chan, H, Simeonov, I, Anthony, K, Zelaya, F, Williams, S, Brammer, M, Mountjoy, P, Bailey, S, Shaw, J, Sicree, R, Dunstan, D, Cameron, A, Zimmet, P, Hewitt, S, Graff iversen, S, Assah, F, Fezeu, L, Kengne, A, Awah, P, Mbanya, J, Shu, J, Kamadjeu, R, Kiawi, E, Kerényi, Z, Péterfalvi, A, Bosnyák, Z, Madarász, E, Tabák, Á, Szánthó, J, Rákóczi, I, Tamás, G, Di Bartolo, P, Valpiani, G, Di Martino, M, Scaramuzza, A, Saragoni, S, Degli Esposti, E, Cannatá, F, Gudbjornsdottir, S, Cederholm, J, Nilsson, P, Eliasson, B, Miettinen, M, Miettinen, J, Nan, H, Dong, Y, Gao, W, Sun, B, Wang, N, Fu, F, Shi, H, Ding, M, Lorenzo, C, Serrano ríos, M, Martínez larrad, M, González sánchez, J, Seclén, S, Villena, A, Gonzalez villalpando, C, Williams, K, Stern, M, Haffner, S, Sakurai, M, Miura, K, Kita, Y, Takamura, T, Ota, T, Ishizaki, M, Morikawa, Y, Nakagawa, H, Szybiński, Z, Szurkowska, M, Mardarowicz, G, Łopatyński, J, Gilis januszewska, A, Szafraniec, K, Nicer, T, Kwon, H, Lee, J, Lee, H, Park, Y, Choi, Y, Jang, S, Song, B, Yoon, K, Lee, W, Cha, B, Lee, K, Son, H, Jørgensen, M, Moustgaard, H, Bjerregaard, P, Ebara, F, Salmon, J, Owen, N, Welborn, T, Armstrong, T, Jolley, D, Galtier, F, Deschamps, V, Borys, J, Lasfargues, G, Andre, P, Born, C, Royer, B, Wilpart, E, Cailleau, M, Eschwege, E, Timar, R, Serban, V, Vlad, A, Diaconu, L, Rosu, M, Olari, O, Sima, A, Qiao, Q, Chappuis, B, Diem, P, Christ, E, Iafusco, D, Prisco, F, Gemma, C, Mattera, S, Sanges, M, Menneila, C, Sommese, L, Jarosz chobot, P, Polanska, J, Feltbower, R, Mckinney, P, Stephenson, C, Bodansky, H, Icks, A, Du Prel, J, Grabert, M, Giani, G, Kyvik, K, Skytthe, A, Ioacara, S, Farcasiu, E, Bradescu, O, Guja, C, Scutaru, G, Savu, O, Ionescu tirgoviste, C, Ola, T, Hawa, M, Buzzetti, R, Scherbaum, W, Kolb, H, Thivolet, C, Hunter, S, Hadden, D, Guntram, S, De Leiva, A, Mauricio, D, Pozzilli, P, Leslie, R, Benediktsson, R, Jonsdottir, A, Einarsdottir, A, Reynisdottir, I, Aspelund, T, Grant, S, Thorleifsson, G, Sigurdsson, G, Stefansson, K, Gudnason, V, Wollitzer, A, Jovanovic, L, Lobo, P, Martí, M, Preiti, M, Urdaneta, R, Juarez, S, Schober, E, Thon, A, Rami, B, Tringham, J, Buyukbese, M, Sakamoto, Y, Inoue, Y, Matsumoto, H, Oono, K, Tokumasa, Y, Gorter, K, Janssen, P, Stolk, R, Van Hessen, P, Rutten, G, Palik, É, Niedermayer, D, Murro, A, Coghi, C, Federici, M, Benedetti, M, Koehler, C, Henkel, E, Temelkova kurktschiev, T, Stier, U, Ott, P, Siegert, G, Bergmann, S, Hanefeld, M, Leonhardt, W, Sayeed, M, Mahtab, H, Khanam, P, Banu, A, Rashid, M, Mulnier, H, Seaman, H, Lovell, D, Soedamah mathu, S, Colhoun, H, Lawrenson, R, Diehm, C, Lange, S, Darius, H, Pittrow, D, Haberl, R, Von Stritzky, B, Tepohl, G, Allenberg, J, Trampisch, H, Soinio, M, Marniemi, J, Laakso, M, Lehto, S, Rönnemaa, T, Ito, C, Sasaki, H, Ishida, S, Maeda, R, Barengo, N, Lakka, T, Köhler, C, Benke, I, Raccah, D, Bailleau, C, Vexiau, P, Vaur, L, Aydin, N, Topsever, P, Filiz, T, Dayan, A, Bulgurlu, S, Gebeloglu, N, Demirtunc, R, Dagar, A, Skliros, E, Sotiropoulos, A, Vassibosis, A, Xipnitos, C, Liva, E, Chronopoulos, I, Merkouris, P, Skourtis, S, Pappas, S, Charbonnel, B, Baigts, F, Dumenil, V, Paillasson, S, Baleydier, A, Hanaire, H, Sert, C, Chabrier, G, Rodier, M, Fontaine, P, Kim, J, Miyake, Y, Sakai, T, Takamatsu, K, Tomioka, Y, Sugano, H, Murao, S, Shimizu, I, Unwin, N, Nag, S, Roglic, G, Connolly, V, Roper, N, Goodwin, J, Kelly, W, Thomsen, R, Hundborg, H, Schønheyder, H, Khalangot, M, Gang, H, Tajima, N, Bianchi, C, Giovannitti, M, Pellegrini, G, Caricato, F, Bertolotto, A, Corfini, M, Guzder, R, Gatling, W, Byrne, C, Varillas, V, Boronat, M, Carrillo, A, La Roche, F, Ojeda, A, López, Y, Marrero, D, Nóvoa, J, Shahidul Alam Khan, A, Thaware, P, Gangat, I, Howlett, T, Jenum, A, Holme, I, Birkeland, K, Sourij, H, Stoschitzky, K, Klein, W, Roth, M, Dittrich, P, Wascher, T, Hilding, A, Eriksson, A, Agardh, E, Efendic, S, Östenson, C, Levitt, N, Bradshaw, D, Salzsieder, E, Freyse, E, Rutscher, A, Heinke, P, Augstein, P, Makino, H, Kainou, Y, Konoue, E, Ohno, K, Ebisui, O, Fujii, Y, Kondo, S, Fujiyama, M, Tanaka, K, Takemoto, K, Kida, K, Onuma, Y, Osawa, H, Tuomilehto wolf, E, Kinnunen, L, Laine, A, Kokko, T, Kakko, T, Hermann, R, Veijola, R, Simell, O, Ilonen, J, Guglielmi, C, Galgani, A, Beretta Anguissola, G, D'Avola, D, Bakhtadze, E, Weiss, H, Wedekind, D, Bilbao, J, San Pedro, J, Vitoria, J, Martul, P, Castaño, L, Badenhoop, K, Ramos Lopez, E, Usadel, K, Wägner, A, Cloos, P, Stahlhut, M, Bergholdt, R, Ramos, E, Taxvig, C, Vella, A, Smyth, D, Cooper, J, Undlien, D, Rønningen, K, Ionescu tîrgovişte, C, Savage, D, Dunger, D, Strachan, D, Ring, S, Todd, J, Mironczuk, K, Kretowski, A, Kinalska, I, Nutland, S, Guja, L, Nielsen, L, Gammeltoft, S, Schwarz, P, Towers, W, Fischer, S, Mcrae, J, Willis, J, Scott, R, Potter, H, Merriman, T, Frampton, C, George, P, Spranger, J, Möhlig, M, Hoffmann, K, Müller, S, Osterhoff, M, Ristow, M, Boeing, H, Pfeiffer, A, Li, Y, Fisher, E, Burwinkel, B, Schrezenmeir, J, Mager, U, Pulkkinen, L, Lindi, V, Lindström, J, Xiu, L, Sui, Y, Weng, J, Kalis, M, Cilio, C, Olde, B, Owman, C, Levéen, P, Da Ros, R, Assaloni, R, Maier, A, Quagliaro, L, Zuodar, G, Zakja, E, Gu, H, Nordman, S, Brookes, A, Prince, J, Helwig, U, Rubin, D, Hampe, J, Schreiber, S, Fölsch, U, Döring, F, Porzio, O, Massa, O, Cunsolo, V, Njolstad, P, Terrinoni, A, Melino, G, Colombo, C, Federici, G, Barbetti, F, Herder, C, Bongardt, F, Schöpfer, A, Rathmann, W, Martin, S, Holle, R, Thorand, B, Wichmann, H, Koenig, W, Illig, T, Blasiak, J, Arabski, M, Krupa, R, Wozniak, K, Dabrowski, J, Kasznicki, J, Zurawska, M, Drzewoski, J, Kose, H, Matsumoto, K, Wilke, B, Kerr bayles, L, Walder, K, Civitarese, A, Jowett, J, Curran, J, Elliott, K, Trevaskis, J, Bishara, N, Wanyonyi, S, Sanigorski, A, Blangero, J, Kissebah, A, Collier, G, Carlsson, E, Arner, P, Ridderstråle, M, Nitz, I, Lindner, I, Suzuki, S, Hinokio, Y, Hirai, M, Yamada, T, Yoshizumi, S, Tanizawa, Y, Matsutani, A, Ishihara, H, Takahashi, K, Katagiri, H, Oka, Y, Nam, M, Hong, S, Ahn, C, Kim, Y, Zeggini, E, Parkinson, J, Groves, C, Frayling, T, Hitman, G, Walker, M, Sampson, M, Levy, J, Weedon, M, Wiltshire, S, Owen, K, Halford, S, Mccarthy, M, Shehadeh, N, Bakri, D, Gershoni baruch, R, Yasuda, K, Okada, T, Sunaga, Y, Kajimoto, Y, Shibasaki, T, Kaburagi, Y, Kadowaki, T, Estalella, I, Rica, I, Vazquez, J, De Andrade, P, Van Den Ouweland, J, Maassen, J, Huoponen, K, Savontaus, M, Dimitrijevic Sreckovic, V, Djordjevic, P, Popovic, S, Gostiljac, D, Canovic, F, Sreckovic, B, Colak, E, Obrenovic, R, Milic, G, Glisic, B, Etemadi, A, Saadat, N, Azizi, F, Tsur, A, Cohen, Y, Yerushalmi, Y, Wainstein, J, Norberg, M, Eriksson, J, Lindahl, B, Andersson, C, Rolandsson, O, Stenlund, H, Weinehall, L, Lecomte, P, Vol, S, Cacès, E, Chabrolle, C, Halimi, J, Nijpels, G, Dekker, J, Bouter, L, Heine, R, Löbner, K, Mollenhauer, U, Baumgarten, A, Com, E, Sargin, M, Karadeniz, S, Sengul, A, Suleymanoglu, Y, Pekcanli, N, Yilmaz, T, Cicero, A, Dormi, A, Miconi, A, D'Addato, S, Laghi, L, Brillante, R, Bernardi, R, Grandi, E, Gaddi, A, Jones, M, Lacey, L, Bergenheim, K, Yamagata, F, Yamakoshi, M, Takahashi, M, Kawazu, S, Festa, A, Hanley, A, Otvos, J, Goff, D, Wajngot, A, Cerasi, E, Baumert, J, Schneider, A, Löwel, H, Roussel, R, Müller brandes, C, Ballmann, M, Nährlich, L, Thalhammer, G, Nastoll, M, Schwarz, J, Johne, U, Erfurth, M, Lüddeke, H, Liebl, A, Kotowa, W, Maclaine, G, Evers, T, Pontiroli, A, Pizzocri, P, Paganelli, M, Folli, F, Jung, D, Park, M, Henriksen, J, Durck, T, Weghuber, D, Roden, M, Tura, A, Pacini, G, Bischof, M, Widhalm, K, Sharp, G, Shanmugam, G, Straub, S, Michael, D, Chow, R, Regazzi, R, Gerona, R, Martin, T, Waselle, L, Tomas, A, Min, L, Pessin, J, Björklund, A, Ma, Z, Portwood, N, Parton, L, Smith, E, Diraison, F, Tsuboi, T, Lehtihet, M, Webb, D, Honkanen, R, Knoch, K, Meisterfeld, R, Bergert, H, Kolpe, M, Altkrüger, A, Saeger, H, Solimena, M, Haspel, D, Aguilar bryan, L, Bryan, J, Ullrich, S, Berchtold, S, Ranta, F, Seebohm, G, Alexander, D, Wulff, P, Kuhl, D, Lang, F, Speier, S, Yang, S, Rose, T, Rupnik, M, Varadi, A, Mitchell, K, Schwappach, B, Bleck, C, Wienbergen, A, Rustenbeck, I, Vieira, E, Gylfe, E, Seissler, J, Wohlrab, U, Schmiegelt, D, Ruetter, R, Herten, M, Lechner, A, Nolan, A, Blacken, R, Habener, J, Gao, R, Ustinov, J, Korsgren, O, Mikkola, M, Lundin, K, Otonkoski, T, Jahr, H, Bieback, K, Kern, S, Brendel, C, Brendel, M, Bretzel, R, Taniguchi, S, Ohgawara, H, Tsuchiya, K, Tsuchiya, M, Okochi, H, Kelter, A, Dohrmann, C, Austen, M, Aicher, B, Maedler, K, Schumann, D, Iwakura, Y, Donath, M, Peter, A, Opel, A, Seufert, J, Fernández, E, Serradas, P, Martín, M, Plachot, C, Bailbé, D, Gangnerau, M, Gavete, M, Fajardo, S, Escrivá, F, Portha, B, Álvarez, C, Lipsett, M, Jamal, A, Hanley, S, Castellarin, M, Rosenberg, L, Bhushan, A, Georgia, S, Calderari, S, Meile, M, Miettinen, P, Palgi, J, Virkamäki, A, Ferris, W, Campbell, S, Armstrong, L, Hole, N, Lako, M, Macfarlane, W, Barbera, A, Altirriba, J, Nadal, B, Larsen, M, Gotfredsen, C, Reusens, B, Sparre, T, Kalbe, L, Leunda, A, Kruhoffer, M, Orntoft, T, Remade, C, Dasilva Xavier, G, Motakis, E, Nason, G, Leibiger, B, Berggren, P, Leibiger, I, Uhles, S, Moede, T, Welters, H, Senkel, S, Erdmann, S, Thomas, H, Morgan, N, Irminger, J, Rickenbach, K, Jackson, D, Chan, S, Dezaki, K, Watanabe, M, Hosoda, H, Kangawa, K, Yada, T, Kühnen, P, Laubner, K, Hernández, R, Silvestre, R, Egido, E, Châtenet, D, Leprince, J, Chartrel, N, Vaudry, H, Marco, J, Zhang, F, Zhang, Q, Tengholm, A, Thore, S, Costes, S, Longuet, C, Broca, C, Baltrusch, S, Dyachok, O, Thams, P, Anwar, M, Capito, K, Radu, R, Fujimoto, S, Mukai, E, Shimono, D, Nabe, K, Shimodahira, M, Kominato, R, Aramaki, Y, Yamada, Y, Seino, Y, Giroix, M, Agascioglu, E, Courtois, P, Malaisse, W, Sener, A, Piquer, S, Barcelo batllori, S, Julia, M, Li, J, Lou, M, Zhang, J, Zhou, Q, Zhao, G, Webb, G, Dalal, S, Garcia, C, Saxena, P, Houk, M, Nenquin, M, Abdel ghany, M, Miele, C, Romano, C, Corbo, V, Maitan, M, Andreozzi, F, Ungaro, P, Oriente, F, Raciti, G, Formisano, P, Beguinot, F, Mcclenaghan, N, Mccluskey, J, Patterson, S, Efanov, A, Sewing, S, Bokvist, K, Gromada, J, Frederiksen, A, Juhl, C, Schwarts, M, Schmitz, O, Andersen, P, Valeri, C, Castelli, M, Bonfante, R, Beyan, H, Elouil, H, Khaldi, M, Evangelista, S, Zeender, E, Berney, T, Franklin, I, Sergeev, P, Chervonsky, A, Nyblom, H, Ahmed, M, Bergsten, P, Sol, E, Kharroubi, I, Ladriere, L, Cnop, M, Moffitt, J, Fielding, B, Currie, J, Staiger, K, Brandhorst, D, Winter, D, Kellerer, M, Oprescu, A, Naassan, A, Klimentova, T, Constantin, S, Tang, C, Uchino, H, Lam, L, Wheeler, M, Fantus, G, Giacca, A, Ortsäter, H, Sundsten, T, Youshikawa, H, Winzell, M, Montrone, C, Martemucci, S, Perrini, S, Caccioppoli, C, Størling, J, Grassetti, D, Scipioni, A, Dotta, F, Yamamoto, N, Tsunekawa, S, Ito, Y, Oiso, Y, Miura, Y, Niki, I, Scrocchi, L, Ha, K, Wang, F, Chen, Y, Wu, L, Fraser, P, Yermen, B, Lilla, V, Kaminski, A, Mathe, Z, Dupraz, P, Zbinden, M, Filo, A, Bucher, P, Rinsch, C, Thorens, B, Pepper, M, Estilles, E, Sigrist, S, Rieger, L, Mandes, K, Bohbot, A, Pinget, M, Kessler, L, Parab, P, Katdare, M, Galande, S, Saha, B, Yoshida, A, Satoh, J, Homo dekarche, F, Coulaud, J, Durant, S, Drexhage, H, Mabley, J, Deb, A, Wallace, R, Pacher, P, Elder, R, Szabo, C, Schlosser, M, Mentel, R, Moya suri, V, Wassmuth, R, Gürtler, L, Ankelo, M, Westerlund, A, Blomberg, K, Hinkkanen, A, Popova, V, Gruzov, M, Afanasyeva, V, Kulikovskaya, A, Melnichenko, S, Mankovsky, B, Zak, K, Koczwara, K, Warncke, K, Kawasaki, E, Imagawa, A, Uchigata, Y, Kobayashi, M, Abiru, N, Yamasaki, H, Eguchi, K, Chrul, S, Polakowska, E, Heinrich, A, Walter, M, Pitocco, D, Visalli, N, Crinò, A, Costantino, F, Manfrini, S, Spera, S, Suraci, C, Patera, P, Matteoli, M, Schiaffini, R, Ghirlanda, G, Leotta, S, Hatziagelaki, E, Tsiavou, A, Degiannis, D, Chaidaroglou, A, Manginas, A, Koniavitou, K, Desai, M, Williams, A, Horton, V, Bingley, P, Cull, C, Citarrella, R, Richiusa, P, Mattina, A, Criscimanna, A, Mantione, L, Bronte, V, Pizzolanti, G, Galluzzo, A, Giordano, C, Giulietti, A, Stoffels, K, Overbergh, L, Mathieu, C, Bilgic, S, Aktas, E, Salman, F, Yillar, G, Yilmaz, M, Deniz, G, Valorani, G, Pozzilli, R, Weets, I, Truyen, I, Verschraegen, I, Van Der Auwera, B, De Schepper, J, Dorchy, H, Lebrethon, M, Van Gaal, L, Van Rooy, P, Pipeleers, D, Gorus, F, Shtandel, S, Atramentova, L, Karachentsev, Y, Kravchun, N, Koval, S, Poltorak, V, Levchenko, T, Snegurakaya, I, Miloslavskiy, D, Bojko, V, Resnik, L, Chico, A, Rojas, I, Julià, M, Novials, A, Bendlová, B, Včelák, J, Vaňková, M, Šrámková, D, Šamalíková, P, Kvasničková, H, Vondra, K, Petrone, A, Vania, A, Zavarella, S, Alemanno, I, Di Cola, S, Ribaudo, M, Leonetti, F, Angel, B, Carrasco, E, Santos, J, Albala, C, Oyarzún, A, Pérez bravo, F, Petry, C, Ong, K, Michelmore, K, Artigas, S, Wingate, D, De Zegher, F, Ibáñez, L, Prestle, J, Adomeit, A, Hammer, E, Zieher, T, Missler, B, Appl, T, Schindler, M, Brodbeck, K, Machicao, F, Just, M, Færgeman, N, Knudsen, J, Quint, M, Tschank, G, Korn, M, Henriksen, E, Dokken, B, Sloniger, J, Dörig, J, Quarré, L, Piatkiewicz, P, Taton, J, Czech, A, Gorski, A, Jebens, E, Brennesvik, E, Ktori, C, Ruzzin, J, Shepherd, P, Jensen, J, Lakka, H, Rankinen, T, Leon, A, Skinner, J, Wilmore, J, Rao, D, Bouchard, C, Vendrell, J, Chacon, M, Garcia españa, A, Fernandez real, J, Gutierrez, C, Richart, C, Takeshita, Y, Shimizu, A, Hamaguchi, E, Kaneko, S, Hřebíček, J, Orel, M, Lichnovská, R, Gwozdziewiczová, S, Chlup, R, Faturos, I, Tournis, S, Fotinakis, P, Thomakos, P, Manousaki, M, Leontsini, D, Taxildaris, K, Mitrakou, A, Hur, K, Shim, W, Cho, Y, Lim, S, Kim, K, Beregszaszi, M, Chevenne, D, Sebag, G, De Kerdanet, M, Huet, F, Polak, M, Lacombe, D, De Paoli, A, Levy marchal, C, Mokhort, T, Shishko, E, Shepelkevich, A, Benito, M, Arribas, M, Valverde, A, Menghini, R, Marchetti, V, Cardellini, M, Sbraccia, P, Lauro, D, Lauro, R, Ali, A, Penny, C, Van Der Merwe, M, Paiker, J, Psaras, G, Ekram, F, Crowther, N, Musri, M, Corominola, H, Casamitjana, R, Párrizas, M, Renström, F, Burén, J, Park, C, Lee, G, Kang, E, Sanchez margalet, V, Gonzalez yanes, C, Diaz troya, S, Rodriguez De Fonseca, F, Mcnamara, M, Boschetti, N, Schmid, D, Spinas, G, Trüb, T, Niessen, M, Kuhlmann, J, Neumann haefelin, C, Belz, U, Juretschke, H, Kramer, W, Herling, A, Markova, I, Oliyarnyk, O, Cahova, M, Manders, R, Koopman, R, Zorenc, A, Keizer, H, Van Loon, L, Straczkowski, M, Kowalska, I, Dzienis straczkowska, S, Nikolajuk, A, Gorska, M, Zabielski, P, Baranowski, M, Gorski, J, De Haan, J, Klomp, D, Heerschap, A, Corpeleijn, E, Budzinski, R, Stengele, I, Schuler, M, Selzle, N, Lehmann lintz, T, Heckel, A, Vavrinkova, H, Meskhishvili, E, Furier, S, Parkes, H, Cooney, G, Alemzadeh, R, Tushaus, K, Nencioni, S, Giovannitti, G, Longo, V, De Vries, R, Kerstens, M, Van Tol, A, Dullaart, R, Mcbride, R, Denke, M, Pearson, T, Battisti, W, Brady, W, Palmisano, J, Tuzova, O, Wahl, H, Hong, Q, Luz, K, Xu, G, Schmülling, R, Liebich, H, Oomen, P, Hattori, H, Smit, A, Scheek, L, Thomaseth, K, Lajoix, A, Gauthey, A, Dietz, S, Jahannault, C, Manteghetti, M, Petit, P, Gross, R, Ostenson, C, Quynh, N, Florén, A, Langel, U, Gedulin, B, Smith, P, Prickett, K, Tryon, M, Barnhill, S, Yeoh, T, Young, A, Hiles, R, Carpenter, T, Serota, D, Schafer, K, Ross, P, Nelson, D, Rebelatto, M, Ikeda, H, Nagashima, K, Tsukiyama, K, Todo, T, Trombetta, M, Boselli, L, Calì, A, Cretti, A, Monauni, T, Bifari, F, Bonora, E, Muggeo, M, Bonadonna, R, Gredal, C, Rosenfalck, A, Dejgaard, A, Hilsted, J, Vankova, M, Sramkova, D, Samalikova, P, Vcelak, J, Kvasnickova, H, Bendlova, B, Rudovich, N, Rochlitz, H, Ritzel, R, Butler, A, Butler, P, Murphy, M, Körner, A, Csillag, J, Pintér, Á, Toman, M, Gray, I, Vielwerth, S, Rinnov, A, Jensen, R, Juul, A, Uitterlinden, P, Bruining, G, Lamberts, S, Rasmussen, E, Malis, C, Ekstrom, C, Arne, A, James, J, Thomas, P, Cavan, D, Owona, A, Ozaki, R, So, W, Tong, P, Chan, M, Wong, G, Cockram, C, Chan, J, Redemann, N, Götz, B, Lahm, P, Mader, G, Tadayyon, M, Oh, Y, Schippmann, V, Kluge, R, Bornstein, S, Joost, H, Bae, H, Lee, B, Vertigan, H, Carroll, D, Griffiths, L, Coghlan, M, Freeman, S, Toffolo, G, Dalla Man, C, Basu, R, Cobelli, C, Bertoldo, A, Price, J, Mathis, C, Mason, N, Holt, D, Kelley, C, Mckolanis, T, Kelley, D, Whyte, M, Jackson, N, Beale, R, Treacher, D, Carroll, P, Jones, R, Umpleby, M, Jaquet, D, Boiko, J, Rigal, O, Czernichow, P, Lévy marchal, C, Qvisth, V, Hagström toft, E, Moberg, E, Bolinder, J, Sjöstrand, M, Gudbjörnsdottir, S, Strindberg, L, Lönnroth, P, Mick, D, Sumarac dumanovic, M, Cvijovic, G, Kendereski, A, Pejkovic, D, Zoric, S, Casanueva, F, Dieguez, C, Singh, R, Basu, A, Chittilapilly, E, Johnson, M, Abdallah, B, Shubeska Stratrova, S, Svendsen, O, Dhatariya, K, Bigelow, M, Nair, K, Lundgren, M, Rüge, T, Myrnäs, T, Gimeno, R, Suri, V, Li, D, Huard, C, Martinez, R, Vettore, M, Sironi, A, Gastaldelli, A, Mari, A, Ciociaro, D, Buzzigoli, E, Pettiti, M, Positano, V, Lombardi, M, Radziuk, J, Pye, S, Brehm, A, Krssak, M, Bernroider, E, Anderwald, C, Nowotny, P, Cline, G, Shulman, G, Kotsa, K, Papazisi, A, Spanopoulos, I, Giovos, I, Suzuki, A, Sobajima, H, Naruse, S, Kitagawa, M, Ishiguro, H, Futakuchi, S, Goto, H, Hines, G, Kennedy, I, Matthews, D, Radikova, Z, Koska, J, Ksinantova, L, Imrich, R, Huckova, M, Vigas, M, Wallace, T, Rajala, U, Hiltunen, L, Keinänen kiukaanniemi, S, Noh, J, Choi, N, Chung, J, Min, Y, Lee, M, Holt, H, Wood, P, Darekar, A, Gross, S, Matthies, K, Weck, M, Malinska, H, Beifort, R, Berria, R, Defronzo, R, Cusi, K, Gorshunska, M, Karachenzev, Y, López bermejo, A, Pratt, K, Hwa, V, Recasens, M, Broch, M, Rosenfeld, R, Fernández real, J, Ricart, W, Grunnet, L, Pedersen, B, Franke, B, Fleming, S, Lemke, N, Laue, C, Pfeuffer, M, Lecube, A, Hernández, C, Genescà, J, García, L, Francisco, G, Simó, R, Kraml, P, Syrovatka, P, Brunerova, L, Smejkalova, V, Potockova, J, Andel, M, Leshchenko, Z, Poltorack, V, Krasova, N, Gladkih, A, Yang, K, Chamson, A, Thyssen, S, Rojo Llobet, A, Christoffersen, B, Raun, K, Fledelius, C, Vinterby, A, Golozoubova, V, Afonso, R, Ribeiro, R, Macedo, M, Guarino, M, Yang, G, Kurita, S, Misu, H, Akahori, H, Cerf, M, Nkomo, X, Muller, C, Du Toit, D, Louw, J, Wolfe coote, S, Nikishin, P, Zagayko, A, Taylor, K, Guo, X, Langefeld, C, Cur, J, Jinagouda, S, Bowden, D, Hokanson, J, Rotter, J, Liew, C, Wise, S, Yeo, K, Teng, C, Fisher, F, Trujillo, M, Hanif, W, Mcternan, P, Barnett, A, Scherer, P, Kumar, S, Kaltenbach, S, Stumvoll, M, Mlynarski, W, Zmyslowska, A, Andrzejewski, W, Shojaee moradie, F, Das, S, Stolinski, M, Jefferson, W, Cramb, R, Shahmanesh, M, Lyngsø, D, Simonsen, L, Bülow, J, Meinardi, J, Sluiter, W, Wolffenbuttel, B, Bonnet, F, Guebre egziabher, F, Rabasa, R, Laville, M, Gosby, A, Maloney, C, Haering, H, Patarrao, R, Lautt, W, Correia, N, Santos, A, Leite, V, Boavida, J, Nanwei, T, Bobbioni harsch, E, Lehmann, T, Sztajzel, J, Morel, P, Huber, O, Chassot, G, Assimacopoulos jeannet, F, Gedulin, G, Baron, A, Hendrickx, H, Lane, J, Coverly, J, Simcox, J, Stocks, J, Brown, L, Beha, A, Juretschke, P, Gerl, M, Klebach, M, Biemer daub, G, Pérez del pulgar, S, Zorzano, A, Heinsbroek, A, D'Alessio, D, Van Dijk, G, Tornero, M, Bailey, C, Mack, C, Wilson, J, Parkes, D, Kusunoki, M, Sakakibara, F, Kato, K, Okabayashi, N, Nakamura, T, Miyata, T, Habu, S, Nakamura, R, Nakasone, Y, Yasaka, T, Ishihara, R, Morikawa, R, Otake, K, Nakaya, Y, Ruzickova, J, Rossmeisl, M, Flachs, P, Sponarova, J, Prazak, T, Matejkova, O, Kopecky, J, Gram, D, Liu, W, Bödvarsdóttir, T, Hansen, J, Sturis, J, Kern, W, Hallschmid, M, Benedict, C, Schultes, B, Born, J, Fehm, H, Westerbacka, J, Lammi, K, Häkkinen, A, Rissanen, A, Yki järvinen, H, Mayr, P, Mertl roetzer, M, Lauster, F, Pohl, M, Lerch, M, Haslbeck, M, Eriksen, J, Rahlfs, V, Serhiyenko, V, Serhiyenko, A, Serhiyenko, L, Radulian, G, Vladica, M, Panaite, C, Balas, B, Derosa, G, Dumas, A, Fiorito, A, Prieto, P, Cancelas, J, Loba, J, Czupryniak, L, Bialasiewicz, P, Pawlowski, M, Nowak, D, Dupuy, O, Le Berre, J, Bordier, L, Rousseau, C, Mayaudon, H, Bauduceau, B, Bossi, A, Meregalli, G, Balini, A, Berzi, D, Cremonesi, B, Cerrato, D, Rezzani, C, Tumiati, M, Han, K, Min, K, Kim, E, Ahn, K, Ahn, H, Argüelles, I, Forga, L, Izquierdo, M, Gorostiaga, E, Fuentes, C, Ibáñez, J, Rivero, A, Baynes, K, Pentecost, C, Bell, J, Thomas, E, Umpleby, A, Kuhl, J, Ruderman, N, Musi, N, Goodyear, L, Patti, M, Thorell, A, Nygren, J, Ljungkvist, O, Degerblad, M, Ståhle, A, Brismar, T, Saha, A, Båvenholm, P, Aydemir, D, Kiran, B, Unal, M, Okumus, N, Kayserilioglu, A, Perkins, J, Kıran, B, Ünal, M, Salman, S, Yıllar, G, Özer, E, Kayserilioǧlu, A, Yılmaz, T, Dinççaǧ, N, Tikkanen, H, Macdonald, A, Harrison, M, Dickinson, H, Bone, A, Watt, P, Østergård, T, Short, K, Saltin, B, Di Mauro, M, Papalia, G, Battiato, R, Giuffrida, D, Boemi, G, Castellino, P, Akter, S, Akhter, A, Pervin, T, Ahmed, S, Ahmed, K, Saleh, F, Chaudhury, H, Tankova, T, Dakovska, G, Lazarova, M, Dakovska, L, Kirilov, G, Koev, D, Torgerson, J, Hauptman, J, Boldrin, M, Pan, C, Gao, Y, Lindgärde, F, Broom, I, Takeda, H, Oana, F, Matsuzawa, A, Hashizume, H, Akahane, S, Cornes, M, Lund, S, Poulsen, G, Frandsen, M, Pedersen, O, Pankiv, V, Yngen, M, Hjemdahl, P, Wallén, N, Florow, D, Leyck Dieken, M, Kitahara, Y, Mine, T, Konya, H, Hamaguchi, T, Satani, K, Umehara, A, Ishikawa, T, Kohri, K, Hasegawa, Y, Suehiro, A, Kakishita, E, Namba, M, Liao, Z, Yao, B, Belcher, G, Mariz, S, Moules, I, Butzer, R, Langenfeld, M, Köder, C, Majali, K, Adiseshiah, M, Betteridge, J, Pratipanawatr, T, Chotmongkol, R, Kanhasura, S, Pratipanawatr, W, Miyazaki, Y, Matsuda, M, Nagasawa, T, Kuroda, J, Dey, D, Chovatia, M, Nag, A, Pandey, B, Nag, B, Thomas, L, Krauth, M, Allgauer, S, Besenfelder, U, Dennenmoser, J, Moon, C, Chae, S, Kim, M, Jo, Y, Shin, J, Ahn, S, Lee, S, Panadero Moya, A, Rodriguez, E, Gonzalo, A, Sánchez vilar, O, Lara, J, Rovira, A, Otto, C, Otto, B, Göke, B, Parhofer, K, Juurinen, L, Tiikkainen, M, Graner, M, Bajaj, M, Suraamornkul, S, Ucak, S, Kurklu, A, Argon, D, Canbek, E, Altuntas, Y, Schöfl, C, Franzen, C, Gregg, R, Swaminathan, A, Frost, C, Nepal, S, Raymond, R, Mosqueda garcia, R, Johns, D, Gilmore, K, Perriello, G, Pampanelli, S, Di Pietro, C, Rinaldi, T, Brunetti, P, Oshinyemi, K, Garcia, S, Curtis, P, Zambanini, A, Home, P, Pocock, S, Dargie, H, Komajda, M, Jones, N, Münscher, C, Potthoff, F, Golbach, U, Weidenhammer, J, Kusterer, K, Lundershausen, R, O'Neill, M, Goldstein, B, Wooddell, M, Strow, L, Waterhouse, B, Cobitz, A, Wyne, K, Porter, L, Weston, W, Chen, T, James, R, Kravitz, B, Pinkowski, D, Ruxer, J, Mozdzan, M, Siejka, A, Kaiser, M, Häuser, C, Jacober, S, Zagar, A, Althouse, S, Pinaire, J, Becker, R, Frick, A, Rave, K, Moses, R, Ways, K, Krones, R, Basir, S, Klein, C, Sawicki, P, Rotella, C, Pala, L, Dicembrini, I, Mannucci, E, Annuzzi, G, De Natale, C, Bozzetto, L, Patti, L, Cipriano, P, Campaigne, B, Malone, J, Bai, S, Reviriego, J, Augendre ferrante, B, Schneider, K, Schweitzer, M, Fach, E, Busch, K, Karimi Anderesi, Z, Haupt, A, Eckert, H, Peiker, J, Fritsche, A, Janka, H, Plewe, G, Kliebe frisch, C, Maxeiner, S, Teng, L, Chan, C, Ernest, C, Skrivanek, Z, Brodows, R, Soon, D, Chung, K, Rußmann, A, Ryysy, L, Hänninen, J, Hulme, S, Kauppinen mäkelin, R, Lahdenperä, S, Lehtonen, R, Levanen, H, Nikkiä, K, Tulokas, T, Virtamo, H, Vahatalo, M, Fulcher, G, Lavalle gonzalez, F, De La Pena, A, Lim, M, Scholtz, H, Derezinski, T, Gerber, R, Hauber, A, Bolinder, B, Johnson, F, Boehm, B, Keiding, J, Raastam, J, Møller, M, Parkner, T, Jørgensen, C, Smedegaard, J, Christiansen, J, Mcdougall, A, Fitch, M, Nelson, G, Mueller, U, Saemann, A, Ishii, H, Iburi, T, Furuya, M, Yamagami, K, Sekine, O, Yamashiro, S, Ishibashi, R, Tsujii, S, Sauriol, L, Lescrauwaet, B, Heckmann, B, Helbig, C, Franke, I, Schiel, R, Oguzhan, B, Gursoy, N, Gutiérrez, E, García, P, Rokeya, B, Hossain, M, Ali, L, Ivanova, O, Gorbenko, N, Gladkich, A, Gorbenko, K, Blase, E, Nguyen, T, Su, G, Gao, H, Carr, E, Wintle, M, Fineman, M, Calara, F, Han, J, Aisporna, M, Zabala, E, Fehse, F, Trautmann, M, Halseth, A, Nauck, M, Kendall, D, Riddle, M, Zhuang, D, Buse, J, Henry, R, Linnebjerg, H, Kothare, P, De La Peña, A, Atkins, M, Bjerre Knudsen, L, Voss, P, Hompesch, M, Filipczak, R, Le, T, Zdravkovic, M, Gumprecht, J, Deacon, C, Plamboeck, A, Guivarch, P, Dreyfus, J, Mathi, S, Castaigne, J, Drucker, D, Kruger, D, Burrell, T, Gloster, M, Crean, J, Herrmann, K, Kovatchev, B, Cox, D, Mccall, A, Whitehouse, F, Chapman, I, Parker, B, Doran, S, Feinle bisset, C, Wishart, J, Lush, C, Mcintyre, S, Deckhut, D, Horowitz, M, El ouaghlidi, A, Rehring, E, Holmes, D, Sallas, W, He, Y, Watson, C, Ligueros saylan, M, Foley, J, Narayanan, S, Thomas, A, Shah, D, Gopalan, B, Vakkalanka, S, Arch, J, Ryskjær, J, Krarup, T, Madsbad, S, Vilsbøll, T, Ciani, S, Bardini, G, Pezzatini, A, Cappadona, A, Joergensen, M, Jensen holm, H, Kristensen, L, Kanstrup, A, Mckillop, A, Duffy, N, Lindsay, J, Bell, P, Hansen, B, Gronemann, S, Wilken, M, Herman, G, Zhao, P, Dietrich, B, Golor, G, Schrodter, A, Keymeulen, B, Lasseter, K, Kipnes, M, Hilliard, D, Tanen, M, De Smet, M, Van Dyck, K, Tanaka, W, Gottesdiener, K, Wagner, J, Hoffmann, T, S, V, Demuth, H, Paule, S, Myers, M, Nikolovski, B, Fujiwara, H, Hosokawa, M, Fukuda, K, Nishi, Y, Fujita, Y, Yamada, K, Ueda, N, Jones leone, A, Yu, T, Barilla, D, Ho, Y, Makrilakis, K, Panagiotakos, D, Dimosthenopoulos, C, Ioannidis, I, Chrysohoou, C, Pitsavos, C, Kuo, S, Levendal, R, Poonsatha, S, Jones, G, Fahey, R, Hoa, N, Norberg, Å, Liepinsh, E, Phan, D, Thuan, N, Jörnvall, H, Sillard, R, Tessari, P, Kiwanuka, E, Cristini, M, Zaramella, M, Enslen, M, Garcia rodenas, C, Yazawa, M, Imai, Y, Ohmura, E, Tsuchida, A, Matsuda, A, Hosaka, D, Horie, H, Ichita, M, Hisano, Y, Woodhead, S, Xu, W, Chen, X, Cavalot, F, Bonomo, K, Perna, P, Bacillo, E, Salacone, P, Gallo, M, Gaia, E, Vinik, A, Yu, D, Heise, M, Freed, M, Aguilera, E, Pellitero, S, Näf, S, Bendtzen, K, Nicoletti, F, Hahn, J, Bochnig, S, Koenig, H, Sporleder, B, Maisonneuve, P, Lowenfels, A, Kerner, W, Lankisch, P, Thai, A, Mohan, V, Khalid, B, Yeo, J, Gasiorowska, A, Talar wojnarowska, R, Malecka panas, E, Schindler, K, Rieger, A, Gmeinhart, B, Schlembacher, K, Merz, P, Ludvik, B, Müller, N, Rodriguez, F, Aas, A, Seljeflot, I, Huang, C, Biswas, N, Hashimoto, N, Kamatani, Y, Suzuki, Y, Yagui, K, Saito, Y, Iwai, R, Takahashi, H, Yoshida, S, Skowronski, M, Zozulinska, D, Juszczyk, J, Wierusz wysocka, B, Peterkova, V, Kuraeva, T, Scherbacheva, L, Andrianova, E, Maximova, V, Titovich, E, Danne, T, Bittner, C, Hanaire broutin, H, Schumicki, D, Souhami, E, Morrison, G, Purewal, T, Weston, P, Šmahelová, A, Rušavý, Z, Kožnarová, R, Loyková, V, Bělobrádková, J, Devries, J, Retnakaran, R, Hochman, J, Melki, V, Zinman, B, Corbi, S, Costanza, F, Fioriti, E, Cappa, M, Jaroň, M, Martínek, V, Piechatzek, R, Klaff, L, Prager, R, Robinson, A, Penfornis, A, Thomas, R, Selam, J, Sola gazagnes, A, Vitacolonna, E, Canonico, V, Fabietti, P, Iorio, M, Orsini Federici, M, Timi, A, Massi Benedetti, M, Sarti, E, Ashwell, S, Gebbie, J, Siebenhofer, A, Plank, J, Berghold, A, Horvath, K, Mrak, P, Jeitler, K, Pieber, T, Heller, S, Gottlieb, P, Paul, J, Chase, P, Menditto, L, Antuña, R, Grimaldi, A, Brun, J, Vialettes, B, Halimi, S, Dubroca, I, Blayo, A, Gómez peralta, F, Santos mazo, E, Payeras más, F, Abreu padín, C, Santos palacios, S, Salvador rodríguez, J, Burge, M, Schroeder, E, Witthaus, E, Johnston, P, Bradley, C, Kudva, Y, Jenkins, G, Pons, G, Quandt, L, Gebel, J, Vogelsang, D, Smith, S, Isley, W, Russell jones, D, Maier, C, Mustapic, D, Schuster, E, Luger, A, Eher, R, Koznarova, R, Rubesova, I, Pelikanova, T, Skibova, J, Sanz, F, Ampudia blasco, F, Gabaldon, J, Catala, M, Carmena, R, Heinemann, L, Kronshage, B, Ward, K, Sass, D, Essenpreis, M, Voelkel, D, Lodwig, V, Nguyen, M, Mondok, A, Friedrich, C, Caduff, A, Totonelli, A, Longhitano, S, Agrò, F, Edelman, S, Morrison, Z, Velazquez, F, Howard, S, Banks, R, Berger, B, Burian, P, Nilsson, K, Karlén, M, Rylander, E, Blonde, L, Freemantle, N, Ross, S, Duhot, D, Eggertsen, R, Hobbs, F, Martinez, L, Stridde, E, Skyler, J, Tusek, C, Stephan, J, Krasner, A, Landschulz, W, Sha, S, Bott, S, Bergenstal, R, Damgé, C, Ubrich, N, Kaltenbacher, M, Maincent, P, Wutte, A, Bock, G, Balent, B, Midtgaard, A, Rønn, B, Edgerton, D, Cherrington, A, Neal, D, Scott, M, Glass, D, Bowen, L, Wilson, W, Hobbs, C, Leach, C, Sivakumaran, S, Strack, T, De Meyts, P, Aladdin, H, Palsgaard, J, Theede, A, Sajid, W, Hinrichsen, J, Klaproth, B, Lademann, J, Østergaard, J, Andersen, A, Boss, A, Cheatham, W, Pfuetzner, A, Larbig, M, Forst, S, Abdollahnia, R, Grenningloh, M, Leatherdale, B, Bartley, E, Schwartz, S, Buchea, O, Hoss, U, Shah, R, Endo, T, Hata, S, Yamazaki, H, Hernandez Campos, S, Busciantella Ricci, N, Kaufman, F, Halvorson, M, Carpenter, S, Cooper, K, Mueller, J, Van Wasen, H, Brumberg, J, Rduch, K, Mertens, S, Reeß, F, Renz, H, Maran, A, Sparacino, G, Pavanini, A, Corazza, S, Crepaldi, M, Poscia, A, Acosta, D, Salcedo, D, Delgado, E, Novoa, J, Hawkins, F, Parramón, M, Mesa, J, Parhimovich, R, Darko, D, Odusanya, P, Pullen, F, Mukherjee, S, Child, D, Redkin, Y, Dreval, A, Bogomolov, V, Östgren, C, Grodzinsky, E, Lindström, K, Borgquist, L, Fegan, G, Hamliton, P, Mccrimmon, R, Evans, M, Fan, X, Ding, Y, Sherwin, R, Boomsma, F, Pramming, S, Fischer, B, Soydan, N, Eckhard, M, Saar, P, Kreuder, J, Linn, T, Holstein, A, Plaschke, A, Ptak, M, Egberts, E, El din, J, Kirchheiner, J, Hoashi, S, Khamis, A, Kilbane, M, Cannon, D, Gribben, A, Firth, R, Kinsley, B, Cranston, I, De Galan, B, De Mol, P, Wennekes, L, Due andersen, R, Lundkvist, J, Jönsson, L, Mukhopadhyay, B, Deans, K, Kesson, C, Jendrike, N, Buck, H, Abicht, A, Haug, C, Freckmann, G, Warren, R, Sommerfield, A, Allen, K, Deary, I, Frier, B, Høi hansen, T, Wu, A, Holtman, V, Tenberken, O, Maurer, H, Al zakwani, I, Bullano, M, Baron, J, Willey, V, Nattrass, M, Kurtzhals, P, Colding jorgensen, M, Massi benedetti, M, Murray, F, Lin, Z, Kølendorf, K, Prasek, M, Philotheou, A, Javashvili, L, Virsaladze, D, Kajaia, N, Raposo, J, Pratas, S, Fernandes, C, Valadas, C, Duarte, R, Gardete correia, L, Locatelli, M, Patera, I, Bottazzo, G, Hadjidakis, D, Mylonakis, A, Raptis, A, Papaefstathiou, A, Hedman, C, Frystyk, J, Fridell, K, Jönsson, A, Lindström, T, Saito, M, Eto, M, Kaku, K, Stotzka, M, Stein, G, Prince, M, Kulzer, B, Scholze, A, Hermanns, N, Kubiak, T, Starostina, E, Shavrikova, E, Furuhashi, N, Hirose, T, Kuroda, M, Kimura, M, Ishizawa, M, Sarui, H, Takeda, N, Furuta, T, Drewelow, S, Lindloh, C, Paddison, C, Faimalie, M, Flett, R, Micheletti, S, Perelli Cippo, P, Mantovani, L, Su, M, Trento, M, Bajardi, M, Passera, P, Miselli, V, Tomalino, M, Borgo, E, Cavallo, F, Porta, M, Miclea, S, Bogatean, M, Hancu, N, Leppert, K, Muller, U, Rittmeier, H, Mchorney, C, Myers, J, Reinecker, H, Meier, J, Gallwitz, B, Askenas, M, Vollmer, K, Schmidt, W, Kyrou, I, Souvatzoglou, E, Cseh, K, Baranyi, E, Kaszas, E, Szocs, A, Melczer, Z, Sikter, M, Szenthe, P, Palik, E, Hajos, P, Pogatsa, G, Winkler, G, Pardo, I, Barros filho, A, Jahan, S, Huq, F, Biswas, K, Chowdhury, T, Khan, A, Ritterath, C, Talai Rad, N, Siegmund, T, Heinze, T, Henrich, W, Siebert, G, Dudenhausen, J, Buhling, K, Kautzky willer, A, Mustafa, S, Winzer, C, Vukovich, T, Shaat, N, Ekelund, M, Lernmark, Å, Ivarsson, S, Zmudzinska, M, Bronisz, A, Pufal, M, Junik, R, Beran, D, Toledano, Y, Giveon, S, Kahan, E, Aycheh, S, Guttman, N, Jaffe, A, Alberti, H, Boudriga, N, Nabli, M, Jaiveer, S, Jaiveer, P, Shaikh, S, Gopinath, A, Morrissey, J, Patel, V, Lenz, M, Dvoynishnikova, O, Mayorov, A, Galstyan, G, Antsiferov, M, Dedov, I, Rybarczyk, M, Scalone, L, Palmer, A, Morgutti, M, Valentine, W, Renaudin, C, Roze, S, Morsanutto, A, Berto, P, Lopatriello, S, Voinovich, D, Gelisio, R, Brändie, M, Russ, W, Greiner, R, Rodríguez, J, Rubio Terrés, C, De Pablos, P, Smith, I, Morgan, C, Tsutskiridze, L, Haag, B, Delbuono, B, Silva, C, Fox, A, Padilla, V, Naraine, K, Cypryk, K, Szymczak, W, Szosland, K, Sobczak, M, Zawodniak szalapska, M, Lewinski, A, Schvarcz, E, Lindqvist, A, Stenninger, E, Östlund, I, Åman, J, Lapolla, A, Dalfrà, M, Di Benedetto, A, Dolci, M, Franzetti, I, Masotti, M, Napoli, A, Salietti, G, Santini, C, Tortul, C, Di Cianni, G, Popow, C, Waldhör, T, Horn, W, Biermann, E, Rihl, J, Riedl, M, Kastner, P, Kollmann, A, Pusch, W, Schreier, G, Hearnshaw, H, Lowe, P, Griffiths, F, Stapperfend, M, Baehring, T, Cosson, E, Benchimol, M, Carbillon, L, Pariès, J, Lormeau, B, Pharisien, I, Tourel, E, Uzan, M, Attali, J, Zabarovskaya, Z, Mulyarchik, O, Barsukov, A, Guseva, T, Begum, K, Haque, L, Bokor, A, Rigó, J, Garamvölgyi, Z, Pusztai, P, Somogyi, A, Hanson, U, Nyström, L, Blohmó, G, Ekbom schnell, A, Östman, J, Persson, B, Parretti, E, Cioni, R, Marzari, C, Masin, M, Scarselli, G, Mello, G, Seghieri, G, De Bellis, A, Anichini, R, Alviggi, L, Franconi, F, Breschi, C, Dworacka, M, Wender ożegowska, E, Winiarska, H, Macugowska, M, Zawiejska, A, Bobkiewicz kozłowska, T, Pietryga, M, Brązert, J, Bousboulas, S, Politakis, P, Papadimitriou, P, Lyu, R, Yin, D, Green, A, Kristensen, J, Rodríguez saldaña, J, Clark, C, Morales De Teresa, M, Escorza domínguez, A, Ortiz gress, A, Monroy mayorga, A, Mejía pedraza, B, Seeliger, S, Kaiser, J, Müller, E, Maxion bergemann, S, Bergemann, R, Goertz, A, Shearer, A, Bagust, A, Schoeffski, O, Shestakova, M, Balabolkin, M, Chugunova, L, Shamkhalova, M, Zaytseva, N, Naumenkova, I, Brevnova, N, Tsibina, L, Rosak, C, Petzoldt, R, Stammer, H, Dehmel, B, Seidel, D, Roth, W, Fennenkötter, U, Gottschall, V, Kanatsuka, A, Lauenborg, J, Jörgensen, T, Hornnes, P, Wagner, O, Zajdenverg, L, Halfoun, V, Oliveira, J, Lencioni, C, Volpe, L, Chatzianagnostou, K, Cuccuru, I, Ghio, A, Pardini, E, Salvadorini, M, Saltiki, A, Korakovouni, A, Stavrianos, H, Zapanti, E, Antsaklis, A, Pithova, P, Sporna, M, Bustani, R, Todd, D, Guerrero, R, Vázquez, M, Amaya, M, Dios, E, Quijada, D, García hernández, N, Astorga, R, Gandhi, R, Jayawarna, C, Fernando, D, Hill, R, Lloyd mostyn, R, Thomson, G, Rewers, A, Bothner, J, Klingensmith, G, Sysoyeva, O, Karlovich, N, Rankins, D, Wellard, M, Werther, G, Northam, E, Kordonouri, O, Haberland, H, Hauschild, M, Kapellen, T, Kraft, V, Wiemann, D, Lange, K, Witte, D, Laude, D, Dabire, H, Hadj Brahim, F, Papanas, N, Papatheodorou, K, Christakidis, D, Papazoglou, D, Giassakis, G, Piperidou, H, Monastiriotis, H, Maltezos, E, Barrett, C, Serghides, H, Tindali, H, Kelly, F, Chiheb, S, Chen, Q, Brahimi, M, Cynober, L, Delaporte, C, Scionti, L, Conti, M, Vermigli, C, Galimberti, G, Cazzetta, G, Bosi, E, Sugimoto, K, Shoji, M, Yasujima, M, Suda, T, Yagihashi, S, Zsengeller, Z, Charniauskaya, T, Abatan, O, Kimura, I, Tsuneki, H, Hara, S, Sasaki, K, Nangle, M, Gibson, T, Yorek, M, Hirooka, H, Stevens, M, Tarhzaoui, K, Cohen boulakia, F, Smith, G, Lestrade, R, Behar, A, Komori, H, Oi, K, Takahashi, D, Kunitou, T, Moroi, M, Philips, J, Marchand, M, Geronooz, I, Scheen, A, Gambardella, S, Ciampittiello, G, Bracaglia, D, Cicconetti, E, Gigli, F, Verri, C, Baroni, A, Frontoni, S, Szabó, M, Germán, M, Farkas, L, Szentendrei, D, Maiello, M, Mandica, S, Morganti, R, Menzinger, G, Bernardi, L, Aso, Y, Wakabayashi, S, Takebayashi, K, Takemura, Y, Inukai, T, Kalter leibovici, O, Lifshitz, A, Yerushalmy, Y, Stern, E, Ogawa, K, Nanjo, K, Kawamori, R, Katayama, S, Shirai, M, Fonseca, V, Seftel, A, Denne, J, Fredlund, P, Buvat, J, Schmitt, H, Van Ahlen, H, Varanese, L, Lips, J, Hoekstra, J, Banga, J, Legros, J, Lufuma, M, Bouter, K, Fan, L, Lu, J, Zheng, Y, Spruce, M, Jones, C, Coppini, D, Lavery, L, Holtz neiderer, K, Mohler, M, Wendel, C, Nixon, B, Jurado, J, Bataller, F, Dorca, A, Garcia, F, Brossa, N, Barnera, T, Pou Torelló, J, Bregovski, V, Karpova, I, Hedetoft, C, Rasmussen, A, Fabrin, J, Driver, V, Thoms, T, Jeffcoate, W, Monaghan, J, Game, F, Dalla Noce, S, Cimmino, M, Caruso, S, Manes, C, Mikoudi, K, Sossidou, E, Pigas, G, Karagianni, D, Skoutas, D, Fotiadis, S, Pruna, S, Eroshkin, I, Vasiljev, Y, Udovichenko, O, Udovichenko, A, Bondarenko, O, Dang, C, Prasad, Y, Anwar, R, Thomas, G, Lobmann, R, Motzkau, M, Pittasch, D, Lehnert, H, Piaggesi, A, Marsocci, A, Fanara, M, Rizzo, L, Palumbo, F, Campi, F, Tedeschi, A, Scatena, A, Goretti, C, Baicchi, U, Chipchase, S, Treece, K, Pound, N, Hill, N, Cyganek, K, Mirkiewicz sieradzka, B, Malecki, M, Wolkow, P, Skupien, J, Naskalska, A, Sieradzki, J, Tapp, R, Tonkin, A, Harper, A, Mccarty, D, Söderberg, S, Taylor, H, Chitson, P, Alberti, G, Sheetz, M, Aiello, L, Davis, M, Milton, R, Arora, V, Hu, K, Girach, A, Vignati, L, Tyrberg, M, Melander, A, Lindblad, U, Giannarelli, R, Coppelli, A, Sartini, M, Aragona, M, Fletcher, E, Ninkovic, S, Foster, L, Jones, D, De Gooyer, T, Stitt, A, Vingrys, A, Wilkinson berka, J, Lewandowska, A, Randeva, H, Komorowski, J, Lewandowski, K, Jurowski, P, Sankar, S, Gos, R, Kowluru, R, Odenbach, S, Shinn, S, Agardh, C, Hultberg, B, Segura, R, Fonollosa, A, Berrone, E, Beltramo, E, Solimine, C, Ubertalli, A, Islam, N, Esteve, E, Fernandez, M, Recas, I, Mauri, S, Biarnes, F, Junca, E, Fernádez real, J, Rössner, S, Stenlof, K, Levy, B, Perry, B, Fitchet, M, Chrysos, G, Kamaratos, A, Lepeniotis, G, Kokkoris, S, Varytimiadis, K, Stasini, F, Mikros, S, Gianneli, D, Tryfinopoulou, K, Melidonis, A, Nikolopoulou, C, Harley, K, Ryder, R, De, P, Vannieuwenhoven, F, Rossing, K, Oliver, N, Goldschmeding, R, Jacobsen, P, Tan, F, Liew, S, Mukherjee, J, Lim, P, Fröjdö, S, Sjölind, L, Parkkonen, M, Mäkinen, V, Tikellis, C, Nieuwenhoven, F, Macisaac, R, Tsalamandris, C, Mcneil, K, Panaiotopoulos, S, Smith, T, Ho, M, Matthews, P, Jerums, G, Hut, H, Van Den Meiracker, A, Nakhjavani, M, Behjati, J, Esteghamati, A, Esfahanian, F, Aghamohamadzadeh, N, Abbasi, M, Kohnert, K, Zander, E, Krabbe, S, Stehouwer, C, Schalkwijk, C, Krarup Hansen, T, Teppo, A, Ebeling, P, Abdella, N, Mojiminiyi, O, Al Dahi, W, Al Mohammedi, H, Al Jebely, S, Neugebauer baba, S, Baba, T, Ohashi, H, Nakajima, S, Hesselmann, C, Watanabe, T, Nargis, M, Zaid, R, Voronko, O, Tchugunova, L, Vikulova, O, Nosikov, V, Liu, L, Zheng, T, Li, M, Zhang, R, Xiang, K, Hadjadj, S, Jeunemaitre, X, Vervoort, G, Veldman, B, Berden, J, Wetzels, J, Singh, B, Holland, M, Baskar, V, Oh, J, Seo, J, Choi, K, Baik, S, Choi, D, Kim, N, Matsumoto, S, Suetsugu, M, Matsutomo, R, Pisarczyk wiza, D, Banaszak, A, Wysocki, H, Usui, H, Shikata, K, Okada, S, Ogawa, D, Yozai, K, Kido, Y, Nagase, R, Ohga, S, Tone, A, Sasaki, M, Wada, J, Unno, Y, Horiuchi, S, Mclennan, S, Kamarinos, M, Waltham, M, Dy, V, Yue, D, Zdychova, J, Komers, R, Cresci, B, Giannini, S, Manuelli, C, Giunti, S, Pinach, S, Ianni Palarchio, A, Arnaldi, L, Vittone, F, Camussi, G, Cavallo Perin, P, Gruden, G, Marshall, S, Jones, S, White, K, Brizzi, M, Dentelli, P, Rosso, A, Calvi, C, Gambino, R, Cassader, M, Salvidio, G, Deferrari, G, Pegoraro, L, Pagano, G, Cavallo perin, P, Oates, R, Ellery, C, Beebe, D, Coutcher, J, Qian, Y, Lowe, V, Appleton, T, Raunig, D, O'Neil, S, Mylari, B, Amazonas, R, Fujita, A, Doi, A, Matsuno, S, Okamoto, K, Matsumoto, E, Furuta, H, Nishi, M, Tsuno, T, Taniguchi, H, Bessho, H, Wasén, E, Isoaho, R, Mattila, K, Vahlberg, T, Kivelä, S, Irjala, K, Rigalleau, V, Lasseur, C, Perlemoine, C, Barthes, N, Raffaitin, C, Chauveau, P, Combe, C, Baillet blanco, L, Beauvieux, M, Gin, H, Heinrich, S, Steiner, T, Ott, U, Holdass, H, Fellström, B, Jardine, A, Staffler, B, Logan, J, Gimpelewicz, C, Stanciu, C, Pena, C, Serafinceanu, C, González posada, J, Hernández, D, Pérez tamajó, L, Ló, A, Herná Alarcó, M, Meneses, M, Barsotti, M, Rizzo, G, Schmauss, S, Havrdova, T, Saudek, F, Boucek, P, Adamec, M, Invitti, C, Gilardini, L, Parati, G, Mazzilli, G, Pontiggia, B, Sartorio, A, Lutgers, H, Groenier, K, Zasadzinska, G, Saryusz wolska, M, Kurktschiev, D, Majdrakova, I, Varbanova, T, Todorova, B, Bajo martinez, A, Bernal, E, Sanchez, O, Ugalde canitrot, A, Sanchez largo, E, Coca robinot, D, Fabregate, R, Calbacho, M, Marquez, J, Saban ruiz, J, Penesova, A, Cizmarova, E, Blazicek, P, De Jongh, R, Serné, E, Ijzerman, R, De Vries, G, Andersen, N, Knudsen, S, Helleberg, K, Mogensen, C, Waluś, M, Idzior waluś, B, Sztefko, K, Cieślik, G, Fedak, D, Wozniakiewicz, E, Lin, S, Guo, M, Lin, C, Liu, X, Francisco, M, Rodriguez rosas, H, Peiró martinez, I, Macías batista, A, Harte, A, Rodriguez cuenca, S, Valsamakis, G, Chetty, R, Anderson, L, Roca, P, Matyka, K, Lasalle, J, Hershon, K, Berman, L, Gibson, E, Gillen, D, Maroni, J, Simmons, D, Hiukka, A, Forder, P, Leinonen, E, Hilden, H, Fruchart, J, Keech, A, Farnier, M, Freeman, M, Macdonell, G, Perevozskaya, I, Mitchel, Y, Gumbiner, B, Didangelos, T, Athyros, V, Mikhailidis, D, Papageorgiou, A, Bouloukos, V, Pehlivanidis, A, Symeonidis, A, Elisaf, M, Mckenney, J, Insull, W, Lewin, A, Maccubbin, D, Kush, D, Schuster, H, Barter, P, Stender, S, Bonnet, J, Morrell, J, Watkins, C, Kallend, D, Stalenhoef, A, Ballantyne, C, Murin, J, Tonstad, S, Rose, H, Wilpshaar, W, Jenkins, A, Karschimkus, C, Dragicevic, G, Rowley, K, Wolthers, T, Best, J, Voet, B, Murdoch, S, Marcovina, S, Brunzell, J, Caparevic, Z, Kostic, N, Ilic, S, Sartore, G, Piarulli, F, Cantaro, S, Reitano, R, Fiore, C, Marin, R, Bassan, S, Manzato, E, Fedele, D, Solini, A, Santini, E, Thornalley, P, Babaei jadidi, R, Karachalias, N, Kupich, C, Ahmed, N, Fowler, A, Baker, A, Starczynski, J, O'Hare, P, Szepietowska, B, Szelachowska, M, Puch, U, Glebocka, A, Quinn, D, Mcternan, C, Bonser, R, Idzior walus, B, Woźniakiewicz, E, Dimitriou, K, Apostolou, O, Kontela, E, Devangelio, E, Gould, E, Serri, O, Roussin, A, Buithieu, J, Mamputu, J, Renier, G, Giordanetti, S, De Amici, E, Poggi, G, Turpini, C, Fratino, P, Garzaniti, A, Banu, I, Paries, J, Roman, G, Negrean, M, Bala, C, Nita, C, Kistorp, C, Gustafsson, F, Chong, A, Lip, G, Galatius, S, Ari, N, Sahilli, M, Ceylan isık, A, Ozansoy, G, Karasu yilmaz, C, Matteucci, E, Rosada, J, Pallini, M, Evangelista, I, Cassetti, G, Giusti, C, Giampietro, O, Capaldo, B, Galderisi, M, Cicala, S, Turco, A, Imbroinise, A, Nosso, G, D'Errico, A, De Divitiis, O, Klimontov, V, Korolyova, E, Jeltova, L, Bondar, I, Tarkun, I, Arslan, B, Canturk, Z, Tarkun, P, Agacdiken, A, Komsuoglu, B, Méneveau, N, Pierre justin, E, Alsayed, M, Sabbah, R, Paulin, S, Marcu, S, Tauveron, I, Zimmermann, C, Schiele, F, Seronde, M, Vautrin, P, Lusson, J, Thieblot, P, Bernard, Y, Mistry, A, Pye, M, Peovska, I, Maksimovic Pavlovic, J, Vavlukis, M, Pop Gorceva, D, Bosevski, M, Scognamiglio, R, Negut, C, De Kreutzenberg, S, Madonna, R, De Caterina, R, Willerson, J, Geng, Y, Vahsen, S, Ledwig, D, Ramrath, S, Frantz, S, Schmidt, I, Calvillo, L, Dienesch, C, Elbing, I, Bischoff, H, Ertl, G, Bauersachs, J, Davydov, A, Mkrtum'Yan, A, Baranova, L, Ikeda, Y, Suehiro, T, Osaki, F, Ota, K, Arii, K, Kumon, Y, Hashimoto, K, Doney, A, Morris, A, Palmer, C, Byun, S, Doo, H, Pagnin, E, Calo, L, Fadini, G, Kubaszek, A, Chai, S, Chai, Q, Rasmussen, L, Ledet, T, Wogensen, L, Lengyel, C, Varró, A, Virág, L, Magyar, J, Bíró, T, Jost, N, Skoumal, R, Nánási, P, Tóth, M, Horkay, F, Papp, J, Zacharopoulou, O, Athanaselis, S, Tsokos, N, Doupis, J, Psallas, M, Cokkinos, D, Pavlatos, S, Liatis, S, Akhobadze, T, Dzneladze, L, Samarguliani, I, Taskiran, M, Rasmussen, V, Jensen, G, Fisher, A, Petrovsky, N, Srikusalanukul, W, Budge, M, Trifunovic zamaklar, D, Zivkovic, M, Jelic, V, Vukomanovic, G, Ristic, A, Seferovic, P, Costa, J, Duarte, S, Manley, S, Sailesh, S, Venkataraman, A, Haider, Y, Groza, I, Oprean, M, Ardelean, A, Morosanu, A, Darkow, T, Vanderplas, A, Mamas, M, Mcelduff, P, Burns, J, Edwards, R, Fitchet, A, Young, R, Gibson, J, Lichiardopol, R, Niculescu, N, Totora, A, Pencea, C, Tomescu, I, Cinteza, M, Manicardi, V, Coscelli, C, Navazio, A, Catellani, E, Michelini, M, Dall'Asta, D, Guberti, A, Piazza, A, Gasparini, E, Pantaleoni, M, Guiducci, U, Manari, A, Sejil, S, Janand delenne, B, Avierinos, J, Habib, G, Labastie, N, Vague, P, Lassmann vague, V, Luźniak, P, Tatoń, J, Wojciechowska Luźniak, A, Zairis, M, Lyras, A, Patsourakos, N, Tsirimbis, V, Foussas, S, Lupón, J, Urrutia, A, Herreros, J, González, B, Coll, R, Altimir, S, Prats, M, Valle, V, Abreu padí, C, Rábago, G, Ivanova, L, Brasacchio, D, Harno, E, Keenan, A, Li, H, Lu, Z, Ke, L, Liu, H, Jeong, I, Chae, M, Choi, M, Yoo, H, Kim, C, Yun, M, Na, M, Kang, Y, Kong, O, Son, S, Kim, I, Tanaka, N, Hosoi, M, Matsuyama, Y, Fukumoto, M, Yamakita, T, Yoshioka, K, Ishii, T, Sato, T, Fujii, S, Aoki, T, Shibata, T, Mizutani, N, Suzuki, J, Fowelin, J, Samuelsson, P, Brandrup wogsen, G, Okumura, K, Tokmakova, A, Staroverova, D, Antcieferov, M, Shutichina, I, Kuntchevich, G, Vriesendorp, T, Morélis, Q, Legemate, D, Schaper, F, Mainas, E, Gkioulmpasanis, I, Panagiotou, I, Vassilikos, G, Skorda, L, Sidira, M, Christoforidou, M, Alaveras, A, Artikis, V, Evdemon, E, Lechleitner, M, Koch, T, Ebenbichler, C, Sturm, W, Moretti, L, Moruzzo, D, Boldrini, E, Pandolfo, C, Kameyama, M, Iwasa, R, Cho, M, Nam, J, Huh, K, Kaplar, M, Paragh, G, Erdei, A, Csongradi, E, Garai, I, Varga, J, Galuska, L, Udvardy, M, Higa, M, Kaneko, Y, Hiroi, N, Koziarska, D, Nowacki, P, Majkowska, L, Luzniak, P, Wojciechowska luźniak, A, Tushuizen, M, Nieuwland, R, Snoeck, D, Sturk, A, Diamant, M, Aguiar, L, Bahia, L, Villela, N, Laflor, C, Conde, C, Bottino, D, Dorigo, D, Bouskela, E, Pu, S, Luo, Z, Lam, K, Dan, Q, Xu, A, Shen, J, Cheng, K, Xu, J, Thamer, C, Stefan, N, Haap, M, Heller, E, Tschritter, O, De Prado, A, Ortiz, A, Ybarra, J, Gich, I, Pou, J, Ehren, M, Roggenland, D, Reinsen, B, Klein, H, Rittig, K, Stock, J, Kocher, B, Balletshofer, B, Shon, H, Chung, D, Nakatani, Y, Matsuhisa, M, Kaneto, H, Hatazaki, M, Yoshiuchi, K, Katakami, N, Kawamori, D, Ohtoshi, K, Sakamoto, K, Matsuoka, T, Ozawa, K, Ogawa, S, Hori, M, Yamasaki, Y, Zitouni, K, Harry, D, Nourooz zadeh, J, Earle, K, Olesen, P, Franco, L, Corvaja, C, Semplicini, A, Ceylan işık, A, Arı, N, Rösen, P, Lee, I, Park, K, Jung, E, Shin, D, Jo, S, Obuobie, K, Prakash, P, Hanna, F, Lazarus, J, Varadhan, L, Gurushankar, J, James, D, Sheikh, S, Gaede, P, Zou, D, Vilarrasa, N, Perez maraver, M, Mena, E, Perez, D, Setti, G, Buckingham, R, Urbančič, V, Stefanovska, A, Bernjak, A, Ažman juvan, K, Kocijančič, A, Glowania, A, Filters, T, Fosmark, D, Torjesen, P, Kilhovd, B, Berg, T, Sandvik, L, Hanssen, K, Mentink, C, Donchenko, G, Stepanenko, S, Maingrette, F, Deng, H, Lindenmair, A, Freudenthaler, A, Baumgartner parzer, S, Nizheradze, K, Khoruzhenko, A, Tronko, N, Sheu, W, Ou, H, Shen, H, Lin, T, Wu, H, Yang, C, Mogylnytska, L, Schmoelzer, I, Davies, J, Band, M, Struthers, A, Prázný, M, Škrha, J, Kasalová, Z, Neelotpol, S, Jahan, P, Kauschke, S, Harrop, C, Schäfer, A, Widder, J, Eigenthaler, M, Walter, U, Uchimura, I, Ikebukuro, M, Kaibara, M, Hirata, M, Helal, R, Pervin, F, Yang, X, Jansson, P, Nagaev, I, Jack, M, Carvalho, E, Sunnerhagen, K, Cam, M, Cushman, S, Smith, U, Creely, S, Farmer, J, Gustafson, B, Kusminski, C, Krusinova, E, Wohl, P, Klementova, M, Lanska, V, Mcdougall, C, Kelly, I, Abbas, Z, Lutale, J, Archibald, L, Karunajeewa, H, Stingemore, N, Stuccio, G, Mcgechie, D, Muller, L, Hak, E, Goudzwaard, W, Montorsi, F, Homering, M, Sprenger, K, Goldstein, I, Asnaghi, V, Ferrari, G, Rastaldi, M, Gabellini, D, Dell'Antonio, G, Maestroni, A, Ruggieri, D, Luzi, L, Piemonti, L, Zerbini, G, Anafaroglu, I, Tutuncu, N, Sultana, M, Siddiqua, N, Iwasaki, T, Nakajima, A, Yoneda, M, Mukasa, K, Tanaka, S, and Sekihara, H
- Subjects
0303 health sciences ,medicine.medical_specialty ,business.industry ,EASD ,Endocrinology, Diabetes and Metabolism ,Human physiology ,medicine.disease ,03 medical and health sciences ,0302 clinical medicine ,Diabetes mellitus ,Family medicine ,Internal Medicine ,Medicine ,business ,030217 neurology & neurosurgery ,030304 developmental biology - Published
- 2004
20. Distinct microRNA and protein profiles of extracellular vesicles secreted from myotubes from morbidly obese donors with type 2 diabetes in response to electrical pulse stimulation.
- Author
-
Aas V, Øvstebø R, Brusletto BS, Aspelin T, Trøseid AS, Qureshi S, Eid DSO, Olstad OK, Nyman TA, and Haug KBF
- Abstract
Lifestyle disorders like obesity, type 2 diabetes (T2D), and cardiovascular diseases can be prevented and treated by regular physical activity. During exercise, skeletal muscles release signaling factors that communicate with other organs and mediate beneficial effects of exercise. These factors include myokines, metabolites, and extracellular vesicles (EVs). In the present study, we have examined how electrical pulse stimulation (EPS) of myotubes, a model of exercise, affects the cargo of released EVs. Chronic low frequency EPS was applied for 24 h to human myotubes isolated and differentiated from biopsy samples from six morbidly obese females with T2D, and EVs, both exosomes and microvesicles (MV), were isolated from cell media 24 h thereafter. Size and concentration of EV subtypes were characterized by nanoparticle tracking analysis, surface markers were examined by flow cytometry and Western blotting, and morphology was confirmed by transmission electron microscopy. Protein content was assessed by high-resolution proteomic analysis (LC-MS/MS), non-coding RNA was quantified by Affymetrix microarray, and selected microRNAs (miRs) validated by real time RT-qPCR. The size and concentration of exosomes and MV were unaffected by EPS. Of the 400 miRs identified in the EVs, EPS significantly changed the level of 15 exosome miRs, of which miR-1233-5p showed the highest fold change. The miR pattern of MV was unaffected by EPS. Totally, about 1000 proteins were identified in exosomes and 2000 in MV. EPS changed the content of 73 proteins in exosomes, 97 in MVs, and of these four were changed in both exosomes and MV (GANAB, HSPA9, CNDP2, and ATP5B). By matching the EPS-changed miRs and proteins in exosomes, 31 targets were identified, and among these several promising signaling factors. Of particular interest were CNDP2, an enzyme that generates the appetite regulatory metabolite Lac-Phe, and miR-4433b-3p, which targets CNDP2. Several of the regulated miRs, such as miR-92b-5p, miR-320b, and miR-1233-5p might also mediate interesting signaling functions. In conclusion, we have used a combined transcriptome-proteome approach to describe how EPS affected the cargo of EVs derived from myotubes from morbidly obese patients with T2D, and revealed several new factors, both miRs and proteins, that might act as exercise factors., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2023 Aas, Øvstebø, Brusletto, Aspelin, Trøseid, Qureshi, Eid, Olstad, Nyman and Haug.)
- Published
- 2023
- Full Text
- View/download PDF
21. Insight Into the Metabolic Adaptations of Electrically Pulse-Stimulated Human Myotubes Using Global Analysis of the Transcriptome and Proteome.
- Author
-
Mengeste AM, Nikolić N, Dalmao Fernandez A, Feng YZ, Nyman TA, Kersten S, Haugen F, Kase ET, Aas V, Rustan AC, and Thoresen GH
- Abstract
Electrical pulse stimulation (EPS) has proven to be a useful tool to interrogate cell-specific responses to muscle contraction. In the present study, we aimed to uncover networks of signaling pathways and regulatory molecules responsible for the metabolic effects of exercise in human skeletal muscle cells exposed to chronic EPS. Differentiated myotubes from young male subjects were exposed to EPS protocol 1 (i.e. 2 ms, 10 V, and 0.1 Hz for 24 h), whereas myotubes from middle-aged women and men were exposed to protocol 2 (i.e. 2 ms, 30 V, and 1 Hz for 48 h). Fuel handling as well as the transcriptome, cellular proteome, and secreted proteins of EPS-treated myotubes from young male subjects were analyzed using a combination of high-throughput RNA sequencing, high-resolution liquid chromatography-tandem mass spectrometry, oxidation assay, and immunoblotting. The data showed that oxidative metabolism was enhanced in EPS-exposed myotubes from young male subjects. Moreover, a total of 81 differentially regulated proteins and 952 differentially expressed genes (DEGs) were observed in these cells after EPS protocol 1. We also found 61 overlapping genes while comparing the DEGs to mRNA expression in myotubes from the middle-aged group exposed to protocol 2, assessed by microarray. Gene ontology (GO) analysis indicated that significantly regulated proteins and genes were enriched in biological processes related to glycolytic pathways, positive regulation of fatty acid oxidation, and oxidative phosphorylation, as well as muscle contraction, autophagy/mitophagy, and oxidative stress. Additionally, proteomic identification of secreted proteins revealed extracellular levels of 137 proteins were changed in myotubes from young male subjects exposed to EPS protocol 1. Selected putative myokines were measured using ELISA or multiplex assay to validate the results. Collectively, our data provides new insight into the transcriptome, proteome and secreted proteins alterations following in vitro exercise and is a valuable resource for understanding the molecular mechanisms and regulatory molecules mediating the beneficial metabolic effects of exercise., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 Mengeste, Nikolić, Dalmao Fernandez, Feng, Nyman, Kersten, Haugen, Kase, Aas, Rustan and Thoresen.)
- Published
- 2022
- Full Text
- View/download PDF
22. The effect of toll-like receptor ligands on energy metabolism and myokine expression and secretion in cultured human skeletal muscle cells.
- Author
-
Tingstad RH, Norheim F, Haugen F, Feng YZ, Tunsjø HS, Thoresen GH, Rustan AC, Charnock C, and Aas V
- Subjects
- Cell Differentiation, Cells, Cultured, Cytokines metabolism, Fatty Acids metabolism, Gene Expression Regulation, Glucose metabolism, Humans, Immunity, Innate, Muscle Fibers, Skeletal metabolism, Oleic Acid metabolism, Polymerase Chain Reaction, RNA, Messenger metabolism, Satellite Cells, Skeletal Muscle metabolism, Cytokines biosynthesis, Energy Metabolism, Interleukin-6 metabolism, Ligands, Muscle, Skeletal metabolism, Toll-Like Receptors metabolism
- Abstract
Skeletal muscle plays an important role in glycaemic control and metabolic homeostasis, making it a tissue of interest with respect to type 2 diabetes mellitus. The aim of the present study was to determine if ligands of Toll-like receptors (TLRs) could have an impact on energy metabolism and myokine expression and secretion in cultured human skeletal muscle cells. The myotubes expressed mRNA for TLRs 1-6. TLR3, TLR4, TLR5 and TLR6 ligands (TLRLs) increased glucose metabolism. Furthermore, TLR4L and TLR5L increased oleic acid metabolism. The metabolic effects of TLRLs were not evident until after at least 24 h pre-incubation of the cells and here the metabolic effects were more evident for the metabolism of glucose than oleic acid, with a shift towards effects on oleic acid metabolism after chronic exposure (168 h). However, the stimulatory effect of TLRLs on myokine expression and secretion was detected after only 6 h, where TLR3-6L stimulated secretion of interleukin-6 (IL-6). TLR5L also increased secretion of interleukin-8 (IL-8), while TLR6L also increased secretion of granulocyte-macrophage colony stimulating factor (GM-CSF). Pre-incubation of the myotubes with IL-6 for 24 h increased oleic acid oxidation but had no effect on glucose metabolism. Thus IL-6 did not mimic all the metabolic effects of the TLRLs, implying metabolic effects beyond the actions of this myokine., (© 2021. The Author(s).)
- Published
- 2021
- Full Text
- View/download PDF
23. Substrate oxidation in primary human skeletal muscle cells is influenced by donor age.
- Author
-
Aas V, Thoresen GH, Rustan AC, and Lund J
- Subjects
- Adult, Age Factors, Humans, Middle Aged, Oxidation-Reduction, Tissue Donors, Energy Metabolism physiology, Muscle, Skeletal metabolism
- Abstract
Primary human myotubes represent an alternative system to intact skeletal muscle for the study of human diseases related to changes in muscle energy metabolism. This work aimed to study if fatty acid and glucose metabolism in human myotubes in vitro were related to muscle of origin, donor gender, age, or body mass index (BMI). Myotubes from a total of 82 donors were established from three different skeletal muscles, i.e., musculus vastus lateralis, musculus obliquus internus abdominis, and musculi interspinales, and cellular energy metabolism was evaluated. Multiple linear regression analyses showed that donor age had a significant effect on glucose and oleic acid oxidation after correcting for gender, BMI, and muscle of origin. Donor BMI was the only significant contributor to cellular oleic acid uptake, whereas cellular glucose uptake did not rely on any of the variables examined. Despite the effect of age on substrate oxidation, cellular mRNA expression of pyruvate dehydrogenase kinase 4 (PDK4) and peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PPARGC1A) did not correlate with donor age. In conclusion, donor age significantly impacts substrate oxidation in cultured human myotubes, whereas donor BMI affects cellular oleic acid uptake.
- Published
- 2020
- Full Text
- View/download PDF
24. Increased Glycolysis and Higher Lactate Production in Hyperglycemic Myotubes.
- Author
-
Lund J, Ouwens DM, Wettergreen M, Bakke SS, Thoresen GH, and Aas V
- Subjects
- Adult, Cells, Cultured, Female, Healthy Volunteers, Humans, Male, Young Adult, Glycolysis, Hyperglycemia metabolism, Lactic Acid biosynthesis, Muscle Fibers, Skeletal metabolism
- Abstract
Previous studies have shown that chronic hyperglycemia impairs glucose and fatty acid oxidation in cultured human myotubes. To further study the hyperglycemia-induced suppression of oxidation, lactate oxidation, mitochondrial function and glycolytic rate were evaluated. Further, we examined the intracellular content of reactive oxygen species (ROS), production of lactate and conducted pathway-ANOVA analysis on microarray data. In addition, the roles of the pentose phosphate pathway (PPP) and the hexosamine pathway were evaluated. Lactic acid oxidation was suppressed in hyperglycemic versus normoglycaemic myotubes. No changes in mitochondrial function or ROS concentration were observed. Pathway-ANOVA analysis indicated several upregulated pathways in hyperglycemic cells, including glycolysis and PPP. Functional studies showed that glycolysis and lactate production were higher in hyperglycemic than normoglycaemic cells. However, there were no indications of involvement of PPP or the hexosamine pathway. In conclusion, hyperglycemia reduced substrate oxidation while increasing glycolysis and lactate production in cultured human myotubes.
- Published
- 2019
- Full Text
- View/download PDF
25. Electrical Pulse Stimulation of Primary Human Skeletal Muscle Cells.
- Author
-
Nikolić N and Aas V
- Subjects
- Cell Differentiation, Humans, Muscle Contraction physiology, Muscle Fibers, Skeletal cytology, Primary Cell Culture, Electric Stimulation, Muscle Fibers, Skeletal physiology
- Abstract
Electrical pulse stimulation (EPS) is an in vitro method of inducing contractions in cultured skeletal muscle cells of human and animal origin. Motor neuron activation of muscle fibers can be replaced by applying EPS on differentiated skeletal muscle cells (myotubes) in culture (Thelen et al. Biochemical J 321:845-848, 1997, Fujita et al. Exp Cell Res 313:1853-1865, 2007).Here we describe two protocols for EPS of human myotubes in 6-well plates: acute, high-frequency (single bipolar pulses of 2 ms, 100 Hz for 200 ms every fifth second for 5-60 min, 10-30 V) and chronic, low-frequency (single bipolar pulses of 2 ms, 1 Hz 10-30 V for 48 h) at the end of a 7 days long differentiation.
- Published
- 2019
- Full Text
- View/download PDF
26. Utilization of lactic acid in human myotubes and interplay with glucose and fatty acid metabolism.
- Author
-
Lund J, Aas V, Tingstad RH, Van Hees A, and Nikolić N
- Subjects
- Adult, Biological Transport, Energy Metabolism, Humans, Oxidation-Reduction, Fatty Acids metabolism, Glucose metabolism, Lactic Acid metabolism, Muscle Fibers, Skeletal metabolism, Muscle, Skeletal metabolism
- Abstract
Once assumed only to be a waste product of anaerobe glycolytic activity, lactate is now recognized as an energy source in skeletal muscles. While lactate metabolism has been extensively studied in vivo, underlying cellular processes are poorly described. This study aimed to examine lactate metabolism in cultured human myotubes and to investigate effects of lactate exposure on metabolism of oleic acid and glucose. Lactic acid, fatty acid and glucose metabolism were studied in myotubes using [
14 C(U)]lactic acid, [14 C]oleic acid and [14 C(U)]glucose, respectively. Myotubes expressed both the MCT1, MCT2, MCT3 and MCT4 lactate transporters, and lactic acid was found to be a substrate for both glycogen synthesis and lipid storage. Pyruvate and palmitic acid inhibited lactic acid oxidation, whilst glucose and α-cyano-4-hydroxycinnamic acid inhibited lactic acid uptake. Acute addition of lactic acid inhibited glucose and oleic acid oxidation, whereas oleic acid uptake was increased. Pretreatment with lactic acid for 24 h did not affect glucose or oleic acid metabolism. By replacing glucose with lactic acid during the whole culturing period, glucose uptake and oxidation were increased by 2.8-fold and 3-fold, respectively, and oleic acid oxidation was increased 1.4-fold. Thus, lactic acid has an important role in energy metabolism of human myotubes.- Published
- 2018
- Full Text
- View/download PDF
27. Myotubes from lean and severely obese subjects with and without type 2 diabetes respond differently to an in vitro model of exercise.
- Author
-
Feng YZ, Nikolić N, Bakke SS, Kase ET, Guderud K, Hjelmesæth J, Aas V, Rustan AC, and Thoresen GH
- Subjects
- Adult, Cells, Cultured, Diabetes Mellitus, Type 2 diagnosis, Electric Stimulation methods, Female, Humans, Insulin Resistance physiology, Male, Middle Aged, Obesity diagnosis, Thinness diagnosis, Diabetes Mellitus, Type 2 metabolism, Exercise physiology, Muscle Fibers, Skeletal metabolism, Obesity metabolism, Severity of Illness Index, Thinness metabolism
- Abstract
Exercise improves insulin sensitivity and oxidative capacity in skeletal muscles. However, the effect of exercise on substrate oxidation is less clear in obese and type 2 diabetic subjects than in lean subjects. We investigated glucose and lipid metabolism and gene expression after 48 h with low-frequency electrical pulse stimulation (EPS), as an in vitro model of exercise, in cultured myotubes established from lean nondiabetic subjects and severely obese subjects (BMI ≥ 40 kg/m(2)) with and without type 2 diabetes. EPS induced an increase in insulin sensitivity but did not improve lipid oxidation in myotubes from severely obese subjects. Thus, EPS-induced increases in insulin sensitivity and lipid oxidation were positively and negatively correlated to BMI of the subjects, respectively. EPS enhanced oxidative capacity of glucose in myotubes from all subjects. Furthermore, EPS reduced mRNA expression of slow fiber-type marker (MYH7) in myotubes from diabetic subjects; however, the protein expression of this marker was not significantly affected by EPS in either of the donor groups. On the contrary, mRNA levels of interleukin-6 (IL-6) and IL-8 were unaffected by EPS in myotubes from diabetic subjects, while IL-6 mRNA expression was increased in myotubes from nondiabetic subjects. EPS-stimulated mRNA expression levels of MYH7, IL-6, and IL-8 correlated negatively with subjects' HbA1c and/or fasting plasma glucose, suggesting an effect linked to the diabetic phenotype. Taken together, these data show that myotubes from different donor groups respond differently to EPS, suggesting that this effect may reflect the in vivo characteristics of the donor groups., (Copyright © 2015 the American Physiological Society.)
- Published
- 2015
- Full Text
- View/download PDF
28. Myotubes from severely obese type 2 diabetic subjects accumulate less lipids and show higher lipolytic rate than myotubes from severely obese non-diabetic subjects.
- Author
-
Bakke SS, Feng YZ, Nikolić N, Kase ET, Moro C, Stensrud C, Damlien L, Ludahl MO, Sandbu R, Solheim BM, Rustan AC, Hjelmesæth J, Thoresen GH, and Aas V
- Subjects
- Diabetes Mellitus, Type 2 metabolism, Energy Metabolism, Fatty Acids metabolism, Humans, Lipase metabolism, Lipolysis, Membrane Proteins metabolism, Obesity metabolism, Oleic Acid metabolism, Oxidation-Reduction, Perilipin-2, Perilipin-3, Phosphorylation, Proto-Oncogene Proteins c-akt metabolism, Severity of Illness Index, Triglycerides metabolism, Vesicular Transport Proteins metabolism, Diabetes Mellitus, Type 2 pathology, Lipid Metabolism physiology, Muscle Fibers, Skeletal metabolism, Obesity pathology
- Abstract
About 80% of patients with type 2 diabetes are classified as overweight. However, only about 1/3 of severely obese subjects have type 2 diabetes. This indicates that several severely obese individuals may possess certain characteristics that protect them against type 2 diabetes. We therefore hypothesized that this apparent paradox could be related to fundamental differences in skeletal muscle lipid handling. Energy metabolism and metabolic flexibility were examined in human myotubes derived from severely obese subjects without (BMI 44±7 kg/m2) and with type 2 diabetes (BMI 43±6 kg/m2). Lower insulin sensitivity was observed in myotubes from severely obese subjects with type 2 diabetes. Lipolysis rate was higher, and oleic acid accumulation, triacylglycerol content, and fatty acid adaptability were lower in myotubes from severely obese subjects with type 2 diabetes compared to severely obese non-diabetic subjects. There were no differences in lipid distribution and mRNA and protein expression of the lipases HSL and ATGL, the lipase cofactor CGI-58, or the lipid droplet proteins PLIN2 and PLIN3. Glucose and oleic acid oxidation were also similar in cells from the two groups. In conclusion, myotubes established from severely obese donors with established type 2 diabetes had lower ability for lipid accumulation and higher lipolysis rate than myotubes from severely obese donors without diabetes. This indicates that a difference in intramyocellular lipid turnover might be fundamental in evolving type 2 diabetes.
- Published
- 2015
- Full Text
- View/download PDF
29. Are cultured human myotubes far from home?
- Author
-
Aas V, Bakke SS, Feng YZ, Kase ET, Jensen J, Bajpeyi S, Thoresen GH, and Rustan AC
- Subjects
- Animals, Cell Differentiation physiology, Diabetes Mellitus, Type 2 metabolism, Humans, Obesity metabolism, Muscle Fibers, Skeletal cytology, Muscle Fibers, Skeletal metabolism, Satellite Cells, Skeletal Muscle cytology, Satellite Cells, Skeletal Muscle metabolism
- Abstract
Satellite cells can be isolated from skeletal muscle biopsies, activated to proliferating myoblasts and differentiated into multinuclear myotubes in culture. These cell cultures represent a model system for intact human skeletal muscle and can be modulated ex vivo. The advantages of this system are that the most relevant genetic background is available for the investigation of human disease (as opposed to rodent cell cultures), the extracellular environment can be precisely controlled and the cells are not immortalized, thereby offering the possibility of studying innate characteristics of the donor. Limitations in differentiation status (fiber type) of the cells and energy metabolism can be improved by proper treatment, such as electrical pulse stimulation to mimic exercise. This review focuses on the way that human myotubes can be employed as a tool for studying metabolism in skeletal muscles, with special attention to changes in muscle energy metabolism in obesity and type 2 diabetes.
- Published
- 2013
- Full Text
- View/download PDF
30. Correction: Electrical Pulse Stimulation of Cultured Human Skeletal Muscle Cells as an In Vitro Model of Exercise.
- Author
-
Nikolić N, Skaret Bakke S, Tranheim Kase E, Rudberg I, Flo Halle I, Rustan AC, Thoresen GH, and Aas V
- Abstract
[This corrects the article DOI: 10.1371/journal.pone.0033203.].
- Published
- 2013
- Full Text
- View/download PDF
31. Remodeling of oxidative energy metabolism by galactose improves glucose handling and metabolic switching in human skeletal muscle cells.
- Author
-
Kase ET, Nikolić N, Bakke SS, Bogen KK, Aas V, Thoresen GH, and Rustan AC
- Subjects
- Carbon Radioisotopes, Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone pharmacology, Cell Differentiation drug effects, Cell Proliferation drug effects, Cells, Cultured, Humans, Mitochondria metabolism, Muscle Fibers, Skeletal cytology, Muscle Fibers, Skeletal drug effects, Oleic Acid metabolism, Oxidation-Reduction drug effects, Energy Metabolism drug effects, Galactose metabolism, Glucose metabolism, Lipid Metabolism drug effects, Mitochondria drug effects, Muscle Fibers, Skeletal metabolism
- Abstract
Cultured human myotubes have a low mitochondrial oxidative potential. This study aims to remodel energy metabolism in myotubes by replacing glucose with galactose during growth and differentiation to ultimately examine the consequences for fatty acid and glucose metabolism. Exposure to galactose showed an increased [(14)C]oleic acid oxidation, whereas cellular uptake of oleic acid uptake was unchanged. On the other hand, both cellular uptake and oxidation of [(14)C]glucose increased in myotubes exposed to galactose. In the presence of the mitochondrial uncoupler carbonylcyanide p-trifluormethoxy-phenylhydrazone (FCCP) the reserve capacity for glucose oxidation was increased in cells grown with galactose. Staining and live imaging of the cells showed that myotubes exposed to galactose had a significant increase in mitochondrial and neutral lipid content. Suppressibility of fatty acid oxidation by acute addition of glucose was increased compared to cells grown in presence of glucose. In summary, we show that cells grown in galactose were more oxidative, had increased oxidative capacity and higher mitochondrial content, and showed an increased glucose handling. Interestingly, cells exposed to galactose showed an increased suppressibility of fatty acid metabolism. Thus, galactose improved glucose metabolism and metabolic switching of myotubes, representing a cell model that may be valuable for metabolic studies related to insulin resistance and disorders involving mitochondrial impairments.
- Published
- 2013
- Full Text
- View/download PDF
32. Electrical pulse stimulation of cultured human skeletal muscle cells as an in vitro model of exercise.
- Author
-
Nikolić N, Bakke SS, Kase ET, Rudberg I, Flo Halle I, Rustan AC, Thoresen GH, and Aas V
- Subjects
- Adenosine Triphosphate metabolism, Base Sequence, Cells, Cultured, Citrate (si)-Synthase metabolism, Culture Media, DNA Primers, Fatty Acids metabolism, Gene Expression Profiling, Glucose metabolism, Humans, In Vitro Techniques, L-Lactate Dehydrogenase metabolism, Lactic Acid metabolism, Mitochondria, Muscle metabolism, Muscle, Skeletal cytology, Muscle, Skeletal metabolism, Oleic Acid metabolism, Phosphocreatine metabolism, Real-Time Polymerase Chain Reaction, Reverse Transcriptase Polymerase Chain Reaction, Electric Stimulation, Exercise, Models, Biological, Muscle, Skeletal physiology
- Abstract
Background and Aims: Physical exercise leads to substantial adaptive responses in skeletal muscles and plays a central role in a healthy life style. Since exercise induces major systemic responses, underlying cellular mechanisms are difficult to study in vivo. It was therefore desirable to develop an in vitro model that would resemble training in cultured human myotubes., Methods: Electrical pulse stimulation (EPS) was applied to adherent human myotubes. Cellular contents of ATP, phosphocreatine (PCr) and lactate were determined. Glucose and oleic acid metabolism were studied using radio-labeled substrates, and gene expression was analyzed using real-time RT-PCR. Mitochondrial content and function were measured by live imaging and determination of citrate synthase activity, respectively. Protein expression was assessed by electrophoresis and immunoblotting., Results: High-frequency, acute EPS increased deoxyglucose uptake and lactate production, while cell contents of both ATP and PCr decreased. Chronic, low-frequency EPS increased oxidative capacity of cultured myotubes by increasing glucose metabolism (uptake and oxidation) and complete fatty acid oxidation. mRNA expression level of pyruvate dehydrogenase complex 4 (PDK4) was significantly increased in EPS-treated cells, while mRNA expressions of interleukin 6 (IL-6), cytochrome C and carnitin palmitoyl transferase b (CPT1b) also tended to increase. Intensity of MitoTracker®Red FM was doubled after 48 h of chronic, low-frequency EPS. Protein expression of a slow fiber type marker (MHCI) was increased in EPS-treated cells., Conclusions: Our results imply that in vitro EPS (acute, high-frequent as well as chronic, low-frequent) of human myotubes may be used to study effects of exercise.
- Published
- 2012
- Full Text
- View/download PDF
33. Chronic hyperglycemia reduces substrate oxidation and impairs metabolic switching of human myotubes.
- Author
-
Aas V, Hessvik NP, Wettergreen M, Hvammen AW, Hallén S, Thoresen GH, and Rustan AC
- Subjects
- 2,4-Dinitrophenol pharmacology, AMP-Activated Protein Kinases metabolism, Adenosine Triphosphate metabolism, Adult, Cells, Cultured, DNA, Mitochondrial genetics, Dose-Response Relationship, Drug, Gene Dosage, Gene Expression Profiling, Humans, Immunoblotting, Lactates metabolism, Lipid Metabolism drug effects, Mitochondria, Muscle drug effects, Mitochondria, Muscle metabolism, Muscle Fibers, Skeletal cytology, Muscle Fibers, Skeletal metabolism, Oligonucleotide Array Sequence Analysis, Oxidation-Reduction drug effects, Phosphorylation drug effects, Protein Biosynthesis drug effects, Reverse Transcriptase Polymerase Chain Reaction, Uncoupling Agents pharmacology, Glucose pharmacology, Muscle Fibers, Skeletal drug effects, Oleic Acid metabolism
- Abstract
Skeletal muscle of insulin resistant individuals is characterized by lower fasting lipid oxidation and reduced ability to switch between lipid and glucose oxidation. The purpose of the present study was to examine if chronic hyperglycemia would impair metabolic switching of myotubes. Human myotubes were treated with or without chronic hyperglycemia (20mmol/l glucose for 4 days), and metabolism of [(14)C]oleic acid (OA) and [(14)C]glucose was studied. Myotubes exposed to chronic hyperglycemia showed a significantly reduced OA uptake and oxidation to CO(2), whereas acid-soluble metabolites were increased compared to normoglycemic cells (5.5mmol/l glucose). Glucose suppressibility, the ability of acute glucose (5mmol/l) to suppress lipid oxidation, was 50% in normoglycemic cells and reduced to 21% by hyperglycemia. Adaptability, the capacity to increase lipid oxidation with increasing fatty acid availability, was not affected by hyperglycemia. Glucose uptake and oxidation were reduced by about 40% after hyperglycemia, and oxidation of glucose in presence of mitochondrial uncouplers showed that net and maximal oxidative capacities were significantly reduced. Hyperglycemia also abolished insulin-stimulated glucose uptake. Moreover, ATP concentration was reduced by 25% after hyperglycemia. However, none of the measured mitochondrial genes were downregulated nor was mitochondrial DNA content. Microarray and real-time RT-PCR showed that no genes were significantly regulated by chronic hyperglycemia. Addition of chronic lactate reduced both glucose and OA oxidation to the same extent as hyperglycemia. In conclusion, chronic hyperglycemia reduced substrate oxidation in skeletal muscle cells and impaired metabolic switching. The effect is most likely due to an induced mitochondrial dysfunction., (Copyright © 2010 Elsevier B.V. All rights reserved.)
- Published
- 2011
- Full Text
- View/download PDF
34. Eicosapentaenoic acid (20:5 n-3) increases fatty acid and glucose uptake in cultured human skeletal muscle cells.
- Author
-
Aas V, Rokling-Andersen MH, Kase ET, Thoresen GH, and Rustan AC
- Subjects
- 3-Phosphoinositide-Dependent Protein Kinases, Adult, CD36 Antigens genetics, Carbon Dioxide metabolism, Cell Differentiation drug effects, Cells, Cultured, Diacylglycerol O-Acyltransferase genetics, Diglycerides metabolism, Extracellular Signal-Regulated MAP Kinases metabolism, Fatty Acids pharmacology, Gene Expression drug effects, Gene Expression genetics, Glucose Transporter Type 1 genetics, Glucose Transporter Type 2 genetics, Glycogen biosynthesis, Humans, Insulin pharmacology, Muscle Cells metabolism, Muscle Fibers, Skeletal drug effects, Muscle Fibers, Skeletal metabolism, Muscle, Skeletal cytology, Oleic Acid metabolism, Oleic Acid pharmacology, Oxidation-Reduction, Phospholipids metabolism, Phosphorylation drug effects, Protein Serine-Threonine Kinases metabolism, RNA, Messenger genetics, RNA, Messenger metabolism, Serum Albumin, Bovine pharmacology, Triglycerides metabolism, p38 Mitogen-Activated Protein Kinases metabolism, Eicosapentaenoic Acid pharmacology, Fatty Acids metabolism, Glucose metabolism, Muscle Cells drug effects, Muscle, Skeletal metabolism
- Abstract
This study was conducted to evaluate the chronic effects of eicosapentaenoic acid (EPA) on fatty acid and glucose metabolism in human skeletal muscle cells. Uptake of [14C]oleate was increased >2-fold after preincubation of myotubes with 0.6 mM EPA for 24 h, and incorporation into various lipid classes showed that cellular triacylgycerol (TAG) and phospholipids were increased 2- to 3-fold compared with control cells. After exposure to oleic acid (OA), TAG was increased 2-fold. Insulin (100 nM) further increased the incorporation of [14C]oleate into all lipid classes for EPA-treated myotubes. Fatty acid beta-oxidation was unchanged, and complete oxidation (CO2) decreased in EPA-treated cells. Basal glucose transport and oxidation (CO2) were increased 2-fold after EPA, and insulin (100 nM) stimulated glucose transport and oxidation similarly in control and EPA-treated myotubes, whereas these responses to insulin were abolished after OA treatment. Lower concentrations of EPA (0.1 mM) also increased fatty acid and glucose uptake. CD36/FAT (fatty acid transporter) mRNA expression was increased after EPA and OA treatment compared with control cells. Moreover, GLUT1 expression was increased 2.5-fold by EPA, whereas GLUT4 expression was unchanged, and activities of the mitogen-activated protein kinase p38 and extracellular signal-regulated kinase were decreased after treatment with OA compared with EPA. Together, our data show that chronic exposure of myotubes to EPA promotes increased uptake and oxidation of glucose despite a markedly increased fatty acid uptake and synthesis of complex lipids.
- Published
- 2006
- Full Text
- View/download PDF
35. Leptin expression in human primary skeletal muscle cells is reduced during differentiation.
- Author
-
Solberg R, Aas V, Thoresen GH, Kase ET, Drevon CA, Rustan AC, and Reseland JE
- Subjects
- Cells, Cultured, Fatty Acids physiology, Glucose physiology, Humans, Leptin biosynthesis, Muscle Fibers, Skeletal cytology, Muscle Fibers, Skeletal metabolism, Muscle, Skeletal cytology, Myoblasts cytology, Myoblasts metabolism, RNA, Messenger metabolism, Receptors, Leptin biosynthesis, Receptors, Leptin genetics, Recombinant Proteins genetics, Recombinant Proteins metabolism, Cell Differentiation physiology, Leptin genetics, Muscle Cells metabolism, Muscle, Skeletal metabolism
- Abstract
We found leptin to be strongly expressed in undifferentiated human myoblasts derived from biopsies of the thigh (Musculus vastus lateralis). Both mRNA expression and secretion of leptin were reduced during in vitro differentiation into primary myotubes. However, the expression of the leptin receptor (OB-Rb) mRNA, was unchanged during differentiation of the muscle cells. Administration of recombinant leptin had no effect on leptin, myogenin, myoD, or GLUT4 mRNA expressions during the period of cellular differentiation. A functional leptin receptor was demonstrated by an acute leptin-induced 1.5-fold increase in ERK activity (P = 0.029). Although mRNA expression of regulation of suppressor of cytokine signaling-3 (SOCS-3) mRNA expression was unaltered, leptin significantly stimulated fatty acid oxidation after 6 h measured as acid soluble metabolites (ASM). Palmitic acid (PA), oleic acid (OA), and eicosapentaenoic acid (EPA), known to modulate leptin expression in other tissues, had no effect on mRNA expression or secretion of leptin from human myotubes. In conclusion, we demonstrate that leptin is highly expressed in undifferentiated human myoblasts and the expression is reduced during differentiation to mature myotubes. The role of leptin in these cells needs to be further characterized., (Copyright 2005 Wiley-Liss, Inc)
- Published
- 2005
- Full Text
- View/download PDF
36. Skeletal muscle lipid accumulation in type 2 diabetes may involve the liver X receptor pathway.
- Author
-
Kase ET, Wensaas AJ, Aas V, Højlund K, Levin K, Thoresen GH, Beck-Nielsen H, Rustan AC, and Gaster M
- Subjects
- Anticholesteremic Agents pharmacology, Cells, Cultured, Gene Expression, Glucose metabolism, Glycogen biosynthesis, Humans, Hydrocarbons, Fluorinated, Liver X Receptors, Middle Aged, Muscle, Skeletal drug effects, Obesity metabolism, Orphan Nuclear Receptors, Sulfonamides, DNA-Binding Proteins metabolism, Diabetes Mellitus, Type 2 metabolism, Lipid Metabolism, Muscle, Skeletal metabolism, Receptors, Cytoplasmic and Nuclear metabolism
- Abstract
Liver X receptors (LXRs) are important regulators of cholesterol and lipid metabolism and are also involved in glucose metabolism. However, the functional role of LXRs in human skeletal muscle is at present unknown. This study demonstrates that chronic ligand activation of LXRs by a synthetic LXR agonist increases the uptake, distribution into complex cellular lipids, and oxidation of palmitate as well as the uptake and oxidation of glucose in cultured human skeletal muscle cells. Furthermore, the effect of the LXR agonist was additive to acute effects of insulin on palmitate uptake and metabolism. Consistently, activation of LXRs induced the expression of relevant genes: fatty acid translocase (CD36/FAT), glucose transporters (GLUT1 and -4), sterol regulatory element-binding protein-1c, peroxisome proliferator-activated receptor-gamma, carnitine palmitoyltransferase-1, and uncoupling protein 2 and 3. Interestingly, in response to activation of LXRs, myotubes from patients with type 2 diabetes showed an elevated uptake and incorporation of palmitate into complex lipids but an absence of palmitate oxidation to CO(2). These results provide evidence for a functional role of LXRs in both lipid and glucose metabolism and energy uncoupling in human myotubes. Furthermore, these data suggest that increased intramyocellular lipid content in type 2 diabetic patients may involve an altered response to activation of components in the LXR pathway.
- Published
- 2005
- Full Text
- View/download PDF
37. Reduced lipid oxidation in skeletal muscle from type 2 diabetic subjects may be of genetic origin: evidence from cultured myotubes.
- Author
-
Gaster M, Rustan AC, Aas V, and Beck-Nielsen H
- Subjects
- Blood Glucose metabolism, Cells, Cultured, Diabetes Mellitus, Type 2 pathology, Diglycerides metabolism, Glycated Hemoglobin metabolism, Humans, Insulin blood, Middle Aged, Muscle Fibers, Skeletal pathology, Muscle, Skeletal metabolism, Muscle, Skeletal pathology, Oxidation-Reduction, Reference Values, Triglycerides metabolism, Diabetes Mellitus, Type 2 genetics, Diabetes Mellitus, Type 2 metabolism, Lipid Metabolism, Muscle Fibers, Skeletal metabolism
- Abstract
Insulin resistance in skeletal muscle in vivo is associated with reduced lipid oxidation and lipid accumulation. It is still uncertain whether changes in lipid metabolism represent an adaptive compensation at the cellular level or a direct expression of a genetic trait. Studies of palmitate metabolism in human myotubes established from control and type 2 diabetic subjects may solve this problem, as genetic defects are preserved and expressed in vitro. In this study, total uptake of palmitic acid was similar in myotubes established from both control and type 2 diabetic subjects under basal conditions and acute insulin stimulation. Myotubes established from diabetic subjects expressed a primary reduced palmitic acid oxidation to carbon dioxide with a concomitantly increased esterification of palmitic acid into phospholipids compared with control myotubes under basal conditions. Triacylglycerol (TAG) content and the incorporation of palmitic acid into diacylglycerol (DAG) and TAG at basal conditions did not vary between the groups. Acute insulin treatment significantly increased palmitate uptake and incorporation of palmitic acid into DAG and TAG in myotubes established from both study groups, but no difference was found in myotubes established from control and diabetic subjects. These results indicate that the reduced lipid oxidation in diabetic skeletal muscle in vivo may be of genetic origin; it also appears that TAG metabolism is not primarily affected in diabetic muscles under basal physiological conditions.
- Published
- 2004
- Full Text
- View/download PDF
38. Electrical stimulation improves insulin responses in a human skeletal muscle cell model of hyperglycemia.
- Author
-
Aas V, Torblå S, Andersen MH, Jensen J, and Rustan AC
- Subjects
- Adult, Glucose metabolism, Humans, Muscle, Skeletal cytology, Muscle, Skeletal metabolism, Electric Stimulation, Hyperglycemia physiopathology, Insulin physiology, Models, Biological, Muscle, Skeletal physiopathology
- Abstract
Myoblasts from human skeletal muscle were isolated from needle biopsy samples of the vastus lateralis of young and healthy volunteers. Contaminating fibroblasts were removed, and myoblasts were fused into differentiated multinucleated myotubes. These myotubes manifested both basal and insulin-stimulated (1-100 nM) glucose transport and glycogen synthesis. Insulin increased 2-deoxyglucose uptake by 1.4-fold and glycogen synthesis by 2.1-fold. Measurements of impedance of cell-covered gold electrodes (ECIS system) showed increased micromotion of caffeine-stimulated cells, showing their ability to contract. Acute electrical stimulation of the myotubes increased 2-deoxyglucose uptake by about 30%. Treatment with high glucose concentrations (10-20 mM) for 2-8 days reduced both basal and insulin-stimulated glucose uptake. Maximal effect was seen after 2 days of treatment with 20 mM glucose. Baseline glucose uptake and glycogen synthesis were reduced by 35%, insulin-stimulated glucose uptake by 25%, and insulin-stimulated glycogen synthesis by 39%. Total cell content of glycogen was not changed by hyperglycemia. The insulin-stimulated glucose uptake in hyperglycemia-treated cells was improved by electrical stimulation of the cells. In conclusion, a model of hyperglycemia has been established, and electrical stimulation improved insulin responses.
- Published
- 2002
- Full Text
- View/download PDF
39. Fibronectin promotes calcium signaling by interferon-gamma in human neutrophils via G-protein and sphingosine kinase-dependent mechanisms.
- Author
-
Aas V, Algerøy S, Sand KL, and Iversen JG
- Subjects
- Calcium metabolism, Calcium pharmacology, Cell Adhesion, Cytosol metabolism, Gelatin metabolism, Humans, Lysophospholipids physiology, Neutrophils drug effects, Neutrophils enzymology, Signal Transduction, Sphingosine analogs & derivatives, Sphingosine physiology, Calcium Signaling, Fibronectins pharmacology, Heterotrimeric GTP-Binding Proteins metabolism, Interferon-gamma pharmacology, Neutrophils metabolism, Phosphotransferases (Alcohol Group Acceptor) metabolism
- Abstract
A common intracellular signal activating polymorphonuclear leukocytes (PMN) in inflammation is a change in cytosolic calcium concentration. Previously, we have shown that interferon-gamma (IFN-gamma) induces transient calcium signals in PMN, but only after intracellular calcium store depletion. Using a digital imaging system, we show that adhesion of PMN is critical for IFN-gamma-induced calcium signals, and with PMN attached to the optimal coating, the calcium signals are evoked even in presence of extracellular calcium, that is, non-depleted calcium stores. Adhesion to fibronectin, pure or extracted from plasma by gelatin, improved the IFN-gamma responses compared with serum, plasma, or vitronectin coats. In accordance with previous observations, IFN-gamma-induced calcium signals in fibronectin adherent cells were totally abolished by the G-protein inhibitor pertussis toxin and were also inhibited by the sphingosine kinase inhibitors dimethylsphingosine (DMS) and N-acetylsphingosine (N-Ac-Sp). PMN contact with fibronectin alone, measured in cells sedimenting onto a fibronectin-coated surface or by addition of fibronectin to glass-adherent cells, evoked transient calcium signals. However, PMN in suspension did not respond to the addition of fibronectin or arginine-glycine-aspartate (RGD). The fibronectin-induced calcium signals were also clearly depressed by pertussis toxin and by the sphingosine kinase inhibitors DMS, dihydrosphingosine (DHS), and N-Ac-Sp. When the product of sphingosine kinase activity, sphingosine 1-phosphate (S1-P), was added to the cells, similar calcium signals were induced, which were dependent on a pertussis toxin-sensitive G-protein activity. Finally, addition of S1-P to the cells prior to stimulation with IFN-gamma partly mimicked the priming effect of fibronectin. In conclusion, fibronectin contact evokes by itself a calcium signal in PMN and further promotes calcium signaling by IFN-gamma. We suggest that fibronectin might activate sphingosine kinase, and that the sphingosine 1-phosphate thereby generated induces a calcium signal via a G-protein-dependent mechanism. Apparently, sphingosine kinase activity is also involved in IFN-gamma induced calcium signals.
- Published
- 2001
- Full Text
- View/download PDF
40. Interferon-gamma elicits a G-protein-dependent Ca2+ signal in human neutrophils after depletion of intracellular Ca2+ stores.
- Author
-
Aas V, Larsen K, and Iversen JG
- Subjects
- Adult, Cell Movement drug effects, Computer Simulation, Dose-Response Relationship, Drug, Egtazic Acid pharmacology, Estrenes pharmacology, Female, GTP-Binding Proteins metabolism, Genistein pharmacology, Humans, Interferon-gamma blood, Male, Middle Aged, Pertussis Toxin, Phosphatidylinositol 3-Kinases metabolism, Protein-Tyrosine Kinases metabolism, Pyrrolidinones pharmacology, Time Factors, Type C Phospholipases metabolism, Virulence Factors, Bordetella pharmacology, Calcium metabolism, Calcium Signaling physiology, Interferon-gamma pharmacology, Neutrophils metabolism
- Abstract
Interferon-gamma (IFN-gamma) has multiple effects on Ca2+ signalling in polymorphonuclear neutrophils (PMNs), including evoked cytosolic Ca2+ transients, increased capacitative calcium influx and increased sequestration of Ca2+ in intracellular stores. The present study was conducted to elucidate the mechanism behind the Ca2+ transients. As observed before, the IFN-gamma-evoked Ca2+ signals were apparent when extracellular Ca2+ was removed. A new finding was that the proportion of responding cells and the extent of calcium release increased with increasing time in EGTA buffer. As assessed by N-formyl-methionyl-leucyl-phenylalanine (fMLP)-stimulated Ca2+ release, the intracellular stores were depleted during this incubation period, and the extent of depletion correlated well with the appearance of IFN-gamma-induced Ca2+ signals. This store dependence of the IFN-gamma-induced Ca2+ signals was confirmed by the appearance of IFN-gamma-evoked Ca2+ signals in the presence of extracellular Ca2+ after store depletion by thapsigargin. The appearance of IFN-gamma-mediated Ca2+-signals in the presence of EGTA indicates that IFN-gamma stimulates Ca2+ release from intracellular stores. This was confirmed by the inability of the calcium transportation blocker La3+ to abolish the IFN-gamma response and the total abrogation of the response by the phospholipase C inhibitor U73122. Although these latter results imply a role for inositol 1,4,5-trisphosphate(IP3) in IFN-gamma signalling, comparison of IFN-gamma-evoked responses with fMLP responses revealed clear differences that suggest different signal-transduction pathways. However, responses to fMLP and IFN-gamma were both depressed by pertussis toxin, and the IFN-gamma responses were, in addition, inhibited by the tyrosine kinase inhibitor genistein. Further evidence of the involvement of tyrosine kinase was a slight stimulatory effect of the protein tyrosine phosphatase inhibitor sodium orthovanadate. The PI-3K activity was of minor importance. In conclusion, we present evidence of a novel signal-transduction mechanism for IFN-gamma in PMNs, dependent on tyrosine kinase activity, a pertussis toxin-sensitive G protein and phospholipase C activity.
- Published
- 1999
- Full Text
- View/download PDF
41. IFN-gamma induces calcium transients and increases the capacitative calcium entry in human neutrophils.
- Author
-
Aas V, Larsen K, and Iversen JG
- Subjects
- Cell Movement drug effects, Humans, Neutrophils metabolism, Thapsigargin pharmacology, Calcium blood, Interferon-gamma pharmacology, N-Formylmethionine Leucyl-Phenylalanine pharmacology, Neutrophils drug effects
- Abstract
We have previously reported that long-term priming of human polymorphonuclear neutrophilic granulocytes (PMN) with interferon-gamma (IFN-gamma) increased the fMLP-stimulated calcium influx. We now show that also after short-term incubation with IFN-gamma, PMN calcium metabolism is modulated. Single adherent cells in three different calcium-containing buffers (high, normal, and low [Ca2+]) were stimulated with the bacterial peptide fMLP or the Ca-ATPase inhibitor thapsigargin (Tg) after about 5 min preincubation with IFN-gamma. The results of this protocol indicated that IFN-gamma increases both calcium influx and calcium sequestration. Store dependent Ca2+ influx, directly measured on readdition of calcium to Tg-treated cells incubated in EGTA buffer, was significantly enhanced in IFN-gamma-treated cells. This effect of IFN-gamma was enhanced by the tyrosine kinase inhibitor herbimycin A. Strikingly, in low extracellular calcium concentrations, IFN-gamma induced calcium transients in 20%-60% of the cells. The proportion of PMN responding with Ca2+ transients increased with decreasing extracellular calcium concentration. Average lagtime from addition of IFN-gamma to a response that could be measured was 7.3 sec, and average increase in [Ca2+] above the basal level was 790 nM. These IFN-gamma-induced transients could not be depressed by herbimycin A. Thus, IFN-gamma can increase capacitative calcium influx, induce calcium transients, and possibly affect calcium sequestration in human PMN.
- Published
- 1998
- Full Text
- View/download PDF
42. Modulation by interferons of human neutrophilic granulocyte migration.
- Author
-
Aas V, Lappegård KT, Siebke EM, and Benestad HB
- Subjects
- Analysis of Variance, Benzoquinones, Cycloheximide pharmacology, Enzyme Inhibitors pharmacology, Humans, Lactams, Macrocyclic, N-Formylmethionine Leucyl-Phenylalanine pharmacology, Neutrophils cytology, Protein Synthesis Inhibitors pharmacology, Protein-Tyrosine Kinases antagonists & inhibitors, Quinones pharmacology, Recombinant Proteins pharmacology, Reference Values, Rifabutin analogs & derivatives, Chemotaxis, Leukocyte drug effects, Interferons pharmacology, Neutrophils drug effects
- Abstract
The effect of various interferons (IFN) on neutrophilic granulocyte (PMN) random and directed migration is incompletely understood. We, therefore, investigated PMN migration with a novel micropore membrane technique. No chemotactic effect of either 10-10000 U/ml IFN-alpha or IFN-beta, or 1-1000 U/ml IFN-gamma was observed on PMN isolated from normal human venous blood. However, when present on both sides of the micropore membrane, all the IFN (1000 U/ml IFN-alpha and IFN-beta, 100 U/ml IFN-gamma) inhibited both random and directed migration toward zymosan-activated serum (ZAS). IFN-gamma was the most potent inhibitory agent and produced an inhibition of about 30%. When the bacterial peptide fMLP was used as a chemoattractant, IFN-gamma also depressed chemotaxis. Taking the reduced random migration of IFN-gamma treated cells into account, however, chemotaxis per se-toward both ZAS and fMLP-was not significantly affected. Random migration and directed migration assessed simultaneously with PMN from the same donor were clearly correlated for both control and IFN-gamma treated cells, suggesting that a general antimotility effect of IFN-gamma might explain both reduced random migration and chemotaxis. The antimotility effect of IFN-gamma was not dependent on protein synthesis or on tyrosine kinase activity. In fact, inhibition of tyrosine kinase with herbimycin A increased the ZAS-stimulated motility of both control and IFN-gamma-inhibited PMN. In conclusion, our data indicate that IFN depress both random and directed PMN migration by mechanisms that do not involve protein synthesis or protein tyrosine kinase activity.
- Published
- 1996
- Full Text
- View/download PDF
43. Interferon-gamma affects protein kinase C activity in human neutrophils.
- Author
-
Aas V, Torjesen P, and Iversen JG
- Subjects
- Amino Acid Sequence, Enzyme Activation, Humans, Hydrogen Peroxide blood, In Vitro Techniques, Molecular Sequence Data, Neutrophils enzymology, Respiratory Burst drug effects, Interferon-gamma pharmacology, Neutrophils drug effects, Oxygen blood, Protein Kinase C agonists
- Abstract
Interferon-gamma (IFN-gamma) is a priming agent of polymorphonuclear neutrophilic granulocyte (PMN) oxygen metabolism, and protein kinase C (PKC) is traditionally believed to play a central role in activation of this oxygen metabolism. In the present study, we have shown that the PKC activity in PMN is affected by IFN-gamma. After only 2 minutes exposure to IFN-gamma (100 U/ml), PKC activity was significantly increased in the noncytosolic fraction of the cells. This increase was transient, but toward the end of the priming period of 2 h, the membrane-associated PKC activity increased again to about 152% of control. In the cytosolic fraction, a small and hardly detectable decrease in PKC activity was observed. Treatment of PMN with granulocyte-macrophage colony-stimulating factor (GM-CSF), another PMN priming agent, showed no significant effects on the PKC activity. When the cells were stimulated with the bacterial peptide fMLP after a priming period with IFN-gamma or GM-CSF for 2 h, no significant difference between treated and control cells could be observed. PMN oxygen metabolism, measured by flow cytometry as an accumulation of the fluorescent compound dichlorofluorescein, was in these experiments significantly primed by IFN-gamma, both at baseline and when stimulated with fMLP. The protein kinase C inhibitors H7 and Ro31-8220 blocked the fMLP responses to some extent, but not completely. However, no significant difference between fMLP responses in control and IFN-gamma-treated cells could be detected after administration of inhibitors.(ABSTRACT TRUNCATED AT 250 WORDS)
- Published
- 1995
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.