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1. Apoptotic cell death in disease—Current understanding of the NCCD 2023

Author

Vitale, Ilio, Pietrocola, Federico, Guilbaud, Emma, Aaronson, Stuart A, Abrams, John M, Adam, Dieter, Agostini, Massimiliano, Agostinis, Patrizia, Alnemri, Emad S, Altucci, Lucia, Amelio, Ivano, Andrews, David W, Aqeilan, Rami I, Arama, Eli, Baehrecke, Eric H, Balachandran, Siddharth, Bano, Daniele, Barlev, Nickolai A, Bartek, Jiri, Bazan, Nicolas G, Becker, Christoph, Bernassola, Francesca, Bertrand, Mathieu JM, Bianchi, Marco E, Blagosklonny, Mikhail V, Blander, J Magarian, Blandino, Giovanni, Blomgren, Klas, Borner, Christoph, Bortner, Carl D, Bove, Pierluigi, Boya, Patricia, Brenner, Catherine, Broz, Petr, Brunner, Thomas, Damgaard, Rune Busk, Calin, George A, Campanella, Michelangelo, Candi, Eleonora, Carbone, Michele, Carmona-Gutierrez, Didac, Cecconi, Francesco, Chan, Francis K-M, Chen, Guo-Qiang, Chen, Quan, Chen, Youhai H, Cheng, Emily H, Chipuk, Jerry E, Cidlowski, John A, Ciechanover, Aaron, Ciliberto, Gennaro, Conrad, Marcus, Cubillos-Ruiz, Juan R, Czabotar, Peter E, D’Angiolella, Vincenzo, Daugaard, Mads, Dawson, Ted M, Dawson, Valina L, De Maria, Ruggero, De Strooper, Bart, Debatin, Klaus-Michael, Deberardinis, Ralph J, Degterev, Alexei, Del Sal, Giannino, Deshmukh, Mohanish, Di Virgilio, Francesco, Diederich, Marc, Dixon, Scott J, Dynlacht, Brian D, El-Deiry, Wafik S, Elrod, John W, Engeland, Kurt, Fimia, Gian Maria, Galassi, Claudia, Ganini, Carlo, Garcia-Saez, Ana J, Garg, Abhishek D, Garrido, Carmen, Gavathiotis, Evripidis, Gerlic, Motti, Ghosh, Sourav, Green, Douglas R, Greene, Lloyd A, Gronemeyer, Hinrich, Häcker, Georg, Hajnóczky, György, Hardwick, J Marie, Haupt, Ygal, He, Sudan, Heery, David M, Hengartner, Michael O, Hetz, Claudio, Hildeman, David A, Ichijo, Hidenori, Inoue, Satoshi, Jäättelä, Marja, Janic, Ana, Joseph, Bertrand, Jost, Philipp J, and Kanneganti, Thirumala-Devi

Subjects
Biochemistry and Cell Biology, Biological Sciences, Underpinning research, 1.1 Normal biological development and functioning, Generic health relevance, Good Health and Well Being, Animals, Humans, Apoptosis, Cell Death, Caspases, Carcinogenesis, Mammals, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Health sciences
Abstract

Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis in mammalian systems have elucidated the key contribution of this process not only to (post-)embryonic development and adult tissue homeostasis, but also to the etiology of multiple human disorders. Consistent with this notion, while defects in the molecular machinery for apoptotic cell death impair organismal development and promote oncogenesis, the unwarranted activation of apoptosis promotes cell loss and tissue damage in the context of various neurological, cardiovascular, renal, hepatic, infectious, neoplastic and inflammatory conditions. Here, the Nomenclature Committee on Cell Death (NCCD) gathered to critically summarize an abundant pre-clinical literature mechanistically linking the core apoptotic apparatus to organismal homeostasis in the context of disease.

Published
2023

2. Patient-specific MDS-RS iPSCs define the mis-spliced transcript repertoire and chromatin landscape of SF3B1-mutant HSPCs

Author

Asimomitis, Georgios, Deslauriers, André G., Kotini, Andriana G., Bernard, Elsa, Esposito, Davide, Olszewska, Malgorzata, Spyrou, Nikolaos, Arango Ossa, Juan, Mortera-Blanco, Teresa, Koche, Richard, Nannya, Yasuhito, Malcovati, Luca, Ogawa, Seishi, Cazzola, Mario, Aaronson, Stuart A., Hellström-Lindberg, Eva, Papaemmanuil, Elli, and Papapetrou, Eirini P.

Published
2022
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4. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

Author

Galluzzi, Lorenzo, Vitale, Ilio, Aaronson, Stuart A, Abrams, John M, Adam, Dieter, Agostinis, Patrizia, Alnemri, Emad S, Altucci, Lucia, Amelio, Ivano, Andrews, David W, Annicchiarico-Petruzzelli, Margherita, Antonov, Alexey V, Arama, Eli, Baehrecke, Eric H, Barlev, Nickolai A, Bazan, Nicolas G, Bernassola, Francesca, Bertrand, Mathieu JM, Bianchi, Katiuscia, Blagosklonny, Mikhail V, Blomgren, Klas, Borner, Christoph, Boya, Patricia, Brenner, Catherine, Campanella, Michelangelo, Candi, Eleonora, Carmona-Gutierrez, Didac, Cecconi, Francesco, Chan, Francis K-M, Chandel, Navdeep S, Cheng, Emily H, Chipuk, Jerry E, Cidlowski, John A, Ciechanover, Aaron, Cohen, Gerald M, Conrad, Marcus, Cubillos-Ruiz, Juan R, Czabotar, Peter E, D’Angiolella, Vincenzo, Dawson, Ted M, Dawson, Valina L, De Laurenzi, Vincenzo, De Maria, Ruggero, Debatin, Klaus-Michael, DeBerardinis, Ralph J, Deshmukh, Mohanish, Di Daniele, Nicola, Di Virgilio, Francesco, Dixit, Vishva M, Dixon, Scott J, Duckett, Colin S, Dynlacht, Brian D, El-Deiry, Wafik S, Elrod, John W, Fimia, Gian Maria, Fulda, Simone, García-Sáez, Ana J, Garg, Abhishek D, Garrido, Carmen, Gavathiotis, Evripidis, Golstein, Pierre, Gottlieb, Eyal, Green, Douglas R, Greene, Lloyd A, Gronemeyer, Hinrich, Gross, Atan, Hajnoczky, Gyorgy, Hardwick, J Marie, Harris, Isaac S, Hengartner, Michael O, Hetz, Claudio, Ichijo, Hidenori, Jäättelä, Marja, Joseph, Bertrand, Jost, Philipp J, Juin, Philippe P, Kaiser, William J, Karin, Michael, Kaufmann, Thomas, Kepp, Oliver, Kimchi, Adi, Kitsis, Richard N, Klionsky, Daniel J, Knight, Richard A, Kumar, Sharad, Lee, Sam W, Lemasters, John J, Levine, Beth, Linkermann, Andreas, Lipton, Stuart A, Lockshin, Richard A, López-Otín, Carlos, Lowe, Scott W, Luedde, Tom, Lugli, Enrico, MacFarlane, Marion, Madeo, Frank, Malewicz, Michal, Malorni, Walter, and Manic, Gwenola

Subjects
Biochemistry and Cell Biology, Biological Sciences, Animals, Cell Death, Humans, Lysosomes, Mitochondrial Membrane Transport Proteins, Mitochondrial Permeability Transition Pore, Necrosis, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Health sciences
Abstract

Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemical, and functional perspectives. Since the field continues to expand and novel mechanisms that orchestrate multiple cell death pathways are unveiled, we propose an updated classification of cell death subroutines focusing on mechanistic and essential (as opposed to correlative and dispensable) aspects of the process. As we provide molecularly oriented definitions of terms including intrinsic apoptosis, extrinsic apoptosis, mitochondrial permeability transition (MPT)-driven necrosis, necroptosis, ferroptosis, pyroptosis, parthanatos, entotic cell death, NETotic cell death, lysosome-dependent cell death, autophagy-dependent cell death, immunogenic cell death, cellular senescence, and mitotic catastrophe, we discuss the utility of neologisms that refer to highly specialized instances of these processes. The mission of the NCCD is to provide a widely accepted nomenclature on cell death in support of the continued development of the field.

Published
2018

8. Blocking immunoinhibitory receptor LILRB2 reprograms tumor-associated myeloid cells and promotes antitumor immunity

Author

Chen, Hui-Ming, van der Touw, William, Wang, Yuan Shuo, Kang, Kyeongah, Mai, Sunny, Zhang, Jilu, Alsina-Beauchamp, Dayanira, Duty, James A., Mungamuri, Sathish Kumar, Zhang, Bin, Moran, Thomas, Flavell, Richard, Aaronson, Stuart, Hu, Hong- Ming, Arase, Hisashi, Ramanathan, Suresh, Flores, Raja, Pan, Ping-Ying, and Chen, Shu-Hsia

Subjects
Gene expression -- Research, Immunotherapy -- Usage, Macrophages -- Research, T cells -- Research, Cancer, Lung cancer, Tumors, Carcinoma, Genes, B cells, Immunoglobulins, Genetic research, Health care industry
Abstract

Tumor-associated myeloid cells maintain immunosuppressive microenvironments within tumors. Identification of myeloidspecific receptors to modulate tumor-associated macrophage and myeloid-derived suppressor cell (MDSC) functions remains challenging. The leukocyte immunoglobulin-like receptor B (LILRB) family members are negative regulators of myeloid cell activation. We investigated how LILRB targeting could modulate tumor-associated myeloid cell function. LILRB2 antagonism inhibited receptor-mediated activation of SHP1/2 and enhanced proinflammatory responses. LILRB2 antagonism also inhibited AKT and STAT6 activation in the presence of M-CSF and IL-4. Transcriptome analysis revealed that LILRB2 antagonism altered genes involved in cell cytoskeleton remodeling, lipid/cholesterol metabolism, and endosomal sorting pathways, as well as changed differentiation gene networks associated with inflammatory myeloid cells as opposed to their alternatively activated phenotype. LILRB2 blockade effectively suppressed granulocytic MDSC and Treg infiltration and significantly promoted in vivo antitumor effects of T cell immune checkpoint inhibitors. Furthermore, LILRB2 blockade polarized tumor-infiltrating myeloid cells from non-small cell lung carcinoma tumor tissues toward an inflammatory phenotype. Our studies suggest that LILRB2 can potentially act as a myeloid immune checkpoint by reprogramming tumor-associated myeloid cells and provoking antitumor immunity., IntroductionMacrophages not only mediate inflammation during infection but also suppress immunity during inflammation resolution (1) and promote immune escape within tumor microenvironments (2). The functional plasticity of macrophage phenotypes is [...]

Published
2018
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9. Prolonging lung cancer response to EGFR inhibition by targeting the selective advantage of resistant cells

Author

Brunet, Lisa, primary, Alexandre, David, additional, Lee, Jiyoung, additional, Blanquer-Rosselló, Maria del Mar, additional, Guernet, Alexis, additional, Chhouri, Houssein, additional, Kherrouche, Zoulika, additional, Arabo, Arnaud, additional, Yao, Shen, additional, Godefroy, David, additional, Dehedin, Julie, additional, Li, Jian-Rong, additional, Duparc, Céline, additional, Jamme, Philippe, additional, Vinchent, Audrey, additional, Bérard, Caroline, additional, Tulasne, David, additional, Arena, Sabrina, additional, Bardelli, Alberto, additional, Cheng, Chao, additional, Cho, Byoung Chul, additional, Coulouarn, Cédric, additional, Aaronson, Stuart A., additional, Cortot, Alexis B., additional, Anouar, Youssef, additional, and Grumolato, Luca, additional

Published
2023
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14. Supplementary Video 7 from Exploiting Allosteric Properties of RAF and MEK Inhibitors to Target Therapy-Resistant Tumors Driven by Oncogenic BRAF Signaling

Author

Adamopoulos, Christos, primary, Ahmed, Tamer A., primary, Tucker, Maxwell R., primary, Ung, Peter M.U., primary, Xiao, Min, primary, Karoulia, Zoi, primary, Amabile, Angelo, primary, Wu, Xuewei, primary, Aaronson, Stuart A., primary, Ang, Celina, primary, Rebecca, Vito W., primary, Brown, Brian D., primary, Schlessinger, Avner, primary, Herlyn, Meenhard, primary, Wang, Qi, primary, Shaw, David E., primary, and Poulikakos, Poulikos I., primary

Published
2023
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15. Supplementary Data 2 from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade

Author

Gong, Yixuan, primary, Wang, Li, primary, Yu, Haocheng, primary, Alpert, Naomi, primary, Cohen, Mitchell D., primary, Prophete, Colette, primary, Horton, Lori, primary, Sisco, Maureen, primary, Park, Sung-Hyun, primary, Lee, Hyun-Wook, primary, Zelikoff, Judith, primary, Chen, Lung-Chi, primary, Hashim, Dana, primary, Suarez-Farinas, Mayte, primary, Donovan, Michael J., primary, Aaronson, Stuart A., primary, Galsky, Matthew, primary, Zhu, Jun, primary, Taioli, Emanuela, primary, and Oh, William K., primary

Published
2023
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16. Supplementary Spreadsheet S5 from p53 Maintains Baseline Expression of Multiple Tumor Suppressor Genes

Author

Pappas, Kyrie, primary, Xu, Jia, primary, Zairis, Sakellarios, primary, Resnick-Silverman, Lois, primary, Abate, Francesco, primary, Steinbach, Nicole, primary, Ozturk, Sait, primary, Saal, Lao H., primary, Su, Tao, primary, Cheung, Pamela, primary, Schmidt, Hank, primary, Aaronson, Stuart, primary, Hibshoosh, Hanina, primary, Manfredi, James, primary, Rabadan, Raul, primary, and Parsons, Ramon, primary

Published
2023
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17. Supplementary Figures from Exploiting Allosteric Properties of RAF and MEK Inhibitors to Target Therapy-Resistant Tumors Driven by Oncogenic BRAF Signaling

Author

Adamopoulos, Christos, primary, Ahmed, Tamer A., primary, Tucker, Maxwell R., primary, Ung, Peter M.U., primary, Xiao, Min, primary, Karoulia, Zoi, primary, Amabile, Angelo, primary, Wu, Xuewei, primary, Aaronson, Stuart A., primary, Ang, Celina, primary, Rebecca, Vito W., primary, Brown, Brian D., primary, Schlessinger, Avner, primary, Herlyn, Meenhard, primary, Wang, Qi, primary, Shaw, David E., primary, and Poulikakos, Poulikos I., primary

Published
2023
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18. Supplementary Video 2 from Exploiting Allosteric Properties of RAF and MEK Inhibitors to Target Therapy-Resistant Tumors Driven by Oncogenic BRAF Signaling

Author

Adamopoulos, Christos, primary, Ahmed, Tamer A., primary, Tucker, Maxwell R., primary, Ung, Peter M.U., primary, Xiao, Min, primary, Karoulia, Zoi, primary, Amabile, Angelo, primary, Wu, Xuewei, primary, Aaronson, Stuart A., primary, Ang, Celina, primary, Rebecca, Vito W., primary, Brown, Brian D., primary, Schlessinger, Avner, primary, Herlyn, Meenhard, primary, Wang, Qi, primary, Shaw, David E., primary, and Poulikakos, Poulikos I., primary

Published
2023
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19. Supplementary Video 6 from Exploiting Allosteric Properties of RAF and MEK Inhibitors to Target Therapy-Resistant Tumors Driven by Oncogenic BRAF Signaling

Author

Adamopoulos, Christos, primary, Ahmed, Tamer A., primary, Tucker, Maxwell R., primary, Ung, Peter M.U., primary, Xiao, Min, primary, Karoulia, Zoi, primary, Amabile, Angelo, primary, Wu, Xuewei, primary, Aaronson, Stuart A., primary, Ang, Celina, primary, Rebecca, Vito W., primary, Brown, Brian D., primary, Schlessinger, Avner, primary, Herlyn, Meenhard, primary, Wang, Qi, primary, Shaw, David E., primary, and Poulikakos, Poulikos I., primary

Published
2023
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20. Supplementary Video 5 from Exploiting Allosteric Properties of RAF and MEK Inhibitors to Target Therapy-Resistant Tumors Driven by Oncogenic BRAF Signaling

Author

Adamopoulos, Christos, primary, Ahmed, Tamer A., primary, Tucker, Maxwell R., primary, Ung, Peter M.U., primary, Xiao, Min, primary, Karoulia, Zoi, primary, Amabile, Angelo, primary, Wu, Xuewei, primary, Aaronson, Stuart A., primary, Ang, Celina, primary, Rebecca, Vito W., primary, Brown, Brian D., primary, Schlessinger, Avner, primary, Herlyn, Meenhard, primary, Wang, Qi, primary, Shaw, David E., primary, and Poulikakos, Poulikos I., primary

Published
2023
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21. Data from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade

Author

Gong, Yixuan, primary, Wang, Li, primary, Yu, Haocheng, primary, Alpert, Naomi, primary, Cohen, Mitchell D., primary, Prophete, Colette, primary, Horton, Lori, primary, Sisco, Maureen, primary, Park, Sung-Hyun, primary, Lee, Hyun-Wook, primary, Zelikoff, Judith, primary, Chen, Lung-Chi, primary, Hashim, Dana, primary, Suarez-Farinas, Mayte, primary, Donovan, Michael J., primary, Aaronson, Stuart A., primary, Galsky, Matthew, primary, Zhu, Jun, primary, Taioli, Emanuela, primary, and Oh, William K., primary

Published
2023
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22. Supplementary Data for Article from p53 Maintains Baseline Expression of Multiple Tumor Suppressor Genes

Author

Pappas, Kyrie, primary, Xu, Jia, primary, Zairis, Sakellarios, primary, Resnick-Silverman, Lois, primary, Abate, Francesco, primary, Steinbach, Nicole, primary, Ozturk, Sait, primary, Saal, Lao H., primary, Su, Tao, primary, Cheung, Pamela, primary, Schmidt, Hank, primary, Aaronson, Stuart, primary, Hibshoosh, Hanina, primary, Manfredi, James, primary, Rabadan, Raul, primary, and Parsons, Ramon, primary

Published
2023
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23. Supplementary Video 4 from Exploiting Allosteric Properties of RAF and MEK Inhibitors to Target Therapy-Resistant Tumors Driven by Oncogenic BRAF Signaling

Author

Adamopoulos, Christos, primary, Ahmed, Tamer A., primary, Tucker, Maxwell R., primary, Ung, Peter M.U., primary, Xiao, Min, primary, Karoulia, Zoi, primary, Amabile, Angelo, primary, Wu, Xuewei, primary, Aaronson, Stuart A., primary, Ang, Celina, primary, Rebecca, Vito W., primary, Brown, Brian D., primary, Schlessinger, Avner, primary, Herlyn, Meenhard, primary, Wang, Qi, primary, Shaw, David E., primary, and Poulikakos, Poulikos I., primary

Published
2023
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24. Supplementary Data 1 from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade

Author

Gong, Yixuan, primary, Wang, Li, primary, Yu, Haocheng, primary, Alpert, Naomi, primary, Cohen, Mitchell D., primary, Prophete, Colette, primary, Horton, Lori, primary, Sisco, Maureen, primary, Park, Sung-Hyun, primary, Lee, Hyun-Wook, primary, Zelikoff, Judith, primary, Chen, Lung-Chi, primary, Hashim, Dana, primary, Suarez-Farinas, Mayte, primary, Donovan, Michael J., primary, Aaronson, Stuart A., primary, Galsky, Matthew, primary, Zhu, Jun, primary, Taioli, Emanuela, primary, and Oh, William K., primary

Published
2023
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25. Data from Exploiting Allosteric Properties of RAF and MEK Inhibitors to Target Therapy-Resistant Tumors Driven by Oncogenic BRAF Signaling

Author

Adamopoulos, Christos, primary, Ahmed, Tamer A., primary, Tucker, Maxwell R., primary, Ung, Peter M.U., primary, Xiao, Min, primary, Karoulia, Zoi, primary, Amabile, Angelo, primary, Wu, Xuewei, primary, Aaronson, Stuart A., primary, Ang, Celina, primary, Rebecca, Vito W., primary, Brown, Brian D., primary, Schlessinger, Avner, primary, Herlyn, Meenhard, primary, Wang, Qi, primary, Shaw, David E., primary, and Poulikakos, Poulikos I., primary

Published
2023
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26. Supplementary Tables from Exploiting Allosteric Properties of RAF and MEK Inhibitors to Target Therapy-Resistant Tumors Driven by Oncogenic BRAF Signaling

Author

Adamopoulos, Christos, primary, Ahmed, Tamer A., primary, Tucker, Maxwell R., primary, Ung, Peter M.U., primary, Xiao, Min, primary, Karoulia, Zoi, primary, Amabile, Angelo, primary, Wu, Xuewei, primary, Aaronson, Stuart A., primary, Ang, Celina, primary, Rebecca, Vito W., primary, Brown, Brian D., primary, Schlessinger, Avner, primary, Herlyn, Meenhard, primary, Wang, Qi, primary, Shaw, David E., primary, and Poulikakos, Poulikos I., primary

Published
2023
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27. Data from p53 Maintains Baseline Expression of Multiple Tumor Suppressor Genes

Author

Pappas, Kyrie, primary, Xu, Jia, primary, Zairis, Sakellarios, primary, Resnick-Silverman, Lois, primary, Abate, Francesco, primary, Steinbach, Nicole, primary, Ozturk, Sait, primary, Saal, Lao H., primary, Su, Tao, primary, Cheung, Pamela, primary, Schmidt, Hank, primary, Aaronson, Stuart, primary, Hibshoosh, Hanina, primary, Manfredi, James, primary, Rabadan, Raul, primary, and Parsons, Ramon, primary

Published
2023
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28. Supplementary Figures from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade

Author

Gong, Yixuan, primary, Wang, Li, primary, Yu, Haocheng, primary, Alpert, Naomi, primary, Cohen, Mitchell D., primary, Prophete, Colette, primary, Horton, Lori, primary, Sisco, Maureen, primary, Park, Sung-Hyun, primary, Lee, Hyun-Wook, primary, Zelikoff, Judith, primary, Chen, Lung-Chi, primary, Hashim, Dana, primary, Suarez-Farinas, Mayte, primary, Donovan, Michael J., primary, Aaronson, Stuart A., primary, Galsky, Matthew, primary, Zhu, Jun, primary, Taioli, Emanuela, primary, and Oh, William K., primary

Published
2023
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29. Supplementary Video 3 from Exploiting Allosteric Properties of RAF and MEK Inhibitors to Target Therapy-Resistant Tumors Driven by Oncogenic BRAF Signaling

Author

Adamopoulos, Christos, primary, Ahmed, Tamer A., primary, Tucker, Maxwell R., primary, Ung, Peter M.U., primary, Xiao, Min, primary, Karoulia, Zoi, primary, Amabile, Angelo, primary, Wu, Xuewei, primary, Aaronson, Stuart A., primary, Ang, Celina, primary, Rebecca, Vito W., primary, Brown, Brian D., primary, Schlessinger, Avner, primary, Herlyn, Meenhard, primary, Wang, Qi, primary, Shaw, David E., primary, and Poulikakos, Poulikos I., primary

Published
2023
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30. Supplementary Data 3 from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade

Author

Gong, Yixuan, primary, Wang, Li, primary, Yu, Haocheng, primary, Alpert, Naomi, primary, Cohen, Mitchell D., primary, Prophete, Colette, primary, Horton, Lori, primary, Sisco, Maureen, primary, Park, Sung-Hyun, primary, Lee, Hyun-Wook, primary, Zelikoff, Judith, primary, Chen, Lung-Chi, primary, Hashim, Dana, primary, Suarez-Farinas, Mayte, primary, Donovan, Michael J., primary, Aaronson, Stuart A., primary, Galsky, Matthew, primary, Zhu, Jun, primary, Taioli, Emanuela, primary, and Oh, William K., primary

Published
2023
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31. Supplementary Video 1 from Exploiting Allosteric Properties of RAF and MEK Inhibitors to Target Therapy-Resistant Tumors Driven by Oncogenic BRAF Signaling

Author

Adamopoulos, Christos, primary, Ahmed, Tamer A., primary, Tucker, Maxwell R., primary, Ung, Peter M.U., primary, Xiao, Min, primary, Karoulia, Zoi, primary, Amabile, Angelo, primary, Wu, Xuewei, primary, Aaronson, Stuart A., primary, Ang, Celina, primary, Rebecca, Vito W., primary, Brown, Brian D., primary, Schlessinger, Avner, primary, Herlyn, Meenhard, primary, Wang, Qi, primary, Shaw, David E., primary, and Poulikakos, Poulikos I., primary

Published
2023
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