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191 results on '"Aarbakke, Jarle"'

1. Rolf Seljelid

Author

Smedsrød, Bård, primary, Aarbakke, Jarle, primary, Rasmussen, Knut, primary, and Stalsberg, Helge, primary

Published
2023
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7. Thiopurine biology and pharmacology

Author

Aarbakke, Jarle, Janka-Schaub, Gritta, and Elion, Gertrude B.

Subjects
Purines -- Health aspects, Methyltransferases -- Analysis, Mercaptopurine -- Health aspects, Biological sciences, Chemistry, Pharmaceuticals and cosmetics industries
Abstract

The thiopurines are routinely administered to patients of various clinical conditions. After metabolism to thiopurine nucleotides, 6-mercatopurine (6-MP), azathioprine (AZA) and 6-thioguanine (6-TG) exert cytotoxicity as inactive pro-drugs. 6-MP is catabolized through xanthine oxidase and methylation catalyzed by thiopurine methyltransferase (TPMT). 6-MP serves as maintenance treatment for acute lymphoblastic leukemia.

Published
1997

11. Arne F. Nordøy

Author

Stalsberg, Helge, primary, Rasmussen, Knut, primary, Seljelid, Rolf, primary, Aarbakke, Jarle, primary, Schrøder, Knut E., primary, and Maltau, Jan Martin, primary

Published
2020
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22. Veien til Norges arktiske universitet

Author

Aarbakke, Jarle

Subjects
VDP::Humaniora: 000, VDP::Samfunnsvitenskap: 200, VDP::Social science: 200, VDP::Humanities: 000
Abstract

Jarle Aarbakke (red.) Dette skriftet –Veien til Norges arktiske universitet – er fortellingen om fusjonen på Tromsøya mellom Universitetet i Tromsø og Høgskolen i Tromsø, og fusjonen mellom Høgskolen i Finnmark og Universitetet i Tromsø. Kongen i statsråd vedtok 15.2.2013 at det fra 1.8.2013 er en fusjonert institusjon med navnet Universitetet i Tromsø – Norges arktiske universitet. Det er tre hovedforutsetninger som har gjort denne utviklingen mulig. Den første er fusjonsprosessen på Tromsøya og det som gikk forut for den. Det andre er sammenfall i tid og tematikk av utviklingen av Nordområdepolitikken til regjeringen Stoltenberg II. Det tredje er implementering av ledelse på alle nivå på Universitetet i Tromsø, som skjøt fart i rektor Jarle Aarbakkes andre og tredje rektorperiode. Dette skriftet samler fem foredrag som universitetsdirektør Lasse Lønnum inviterte til å holdes i forbindelse med Jarle Aarbakkes 70-årsdag 18.11.2012, samt foredraget Jonar Gahr Støre holdt 4.4.2013 på universitetets årsfest, da han mottok diplom som æresdoktor ved Universitetet i Tromsø. Det bindes så sammen i en tekst av Jarle Aarbakke, rektor ved universitetet i Tromsø i perioden 2002-2013.

Published
2013

23. Opening

Author

Aarbakke, Jarle

Subjects
Forum for Development Cooperation with Indigenous Peoples
Abstract

Presentation at the 11th annual Forum for Development Cooperation with Indigenous Peoples, which commenced the 24th-26th of October 2010. The Centre for Sámi Studies hosted the conference at the University of Tromsø, Norway.Full conference report available in Munin at http://hdl.handle.net/10037/2941

Published
2010

50. No Effect of Acute Ethanol Administration on Hepatic Protein Synthesis and Export in the Rat in Vivo.

Author

Wallin, Bengt, Bessesen, Atle, Fikke, Anne-Marie, Aarbakke, Jarle, and Morland, Jorg

Abstract

Ethanol was administered as a single p.o. dose (2.88 g kg-1) to male rats (220-265 g body weight) to give blood alcohol concentrations of 40-50 IDM for the following 3 hr. Controls were given isoenergetic amounts of either sucrose or lipid. Liver protein synthetic rates were measured during a 20 min interval at the end of the 3 hr period following the administration of diets. Although ethanol caused a 32% reduction of the incorporation of labelled valine into liver protein compared to the sucrose group during the 20 min interval, no such reduction was found when the synthetic rate of stationary liver protein was calculated (182 vs. 214 (not significant) pmol mg protein-1 min-1) for same interval. There was no difference between the ethanol and lipid group with regard to either incorporation or synthetic rates. Incorporation of valine into plasma proteins was reduced in the ethanol group compared to the sucrose group, but not compared to the lipid control group, again demonstrating no ethanol-specific effect When the incorporation into plasma proteins was divided by the specific radioactivity of valyl-tRNA at 20 min, the difference between the ethanol and the sucrose group disappeared. The fraction of newly synthesized proteins exported to the plasma measured 40 min after the injection of labeled valine, was equal in all three treatment groups. It was concluded that acute administration of ethanol has no consistent effect on liver protein synthesis and secretion in vivo. [ABSTRACT FROM AUTHOR]

Published
1984
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