1. Zona pellucida removal resulted in a successful live birth: Report on a case with recurrent implantation failure due to embryonic bacteria contamination
- Author
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Son Truong Dang, Huy Phuong Tran, Tuong Nguyen Ho, Loc Thai Ly, Tuyet Thi‐Diem Hoang, Trang Nguyen‐Khanh Huynh, Anh Tuan Do, Thuan Duc Nguyen, and Phuong Thi Dao
- Subjects
contaminated embryo ,embryo transfer ,IVF ,recurrent implantation failure ,zona pellucida removal ,Medicine ,Medicine (General) ,R5-920 - Abstract
Key clinical message In in vitro fertilization (IVF), laser offers several advantages. In this study, we employed laser to eliminate the zona pellucida of a contaminated embryo. This approach helps to rescue embryo with bacterial contamination, and improve embryo‐endometrium interaction. Abstract To present a case report on the removal of a contaminated zona pellucida from an embryo of patient with a history of recurrent implantation failure (RIF), which was followed by a successful live birth. We present the case of a 34‐year‐old patient with a history of 3 years of infertility who underwent in vitro fertilization. During the culture process, the embryos became contaminated, leading to three failed implantations. Despite the aneuploidy of the embryo and the implementation of a washing technique, the contamination persisted. In the final attempt, the contaminated zona pellucida was successfully removed using laser, followed by embryo transfer, resulting in a live birth. We provided detailed clinical information, including patient demographics, infertility history, ovarian response, evidence of bacterial contamination, embryo development, treatment protocols, and outcomes. Laser excision of the zona pellucida is a safe and effective method for addressing bacterial infection in embryos.
- Published
- 2024
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