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1. The advantages of home-care enteral nutrition

Author

Andreoli, M., Bertasi, V., Borroni, F., Calzona, A.B., Caravella, G., Crosasso, P., De Montis, S., Ladisa, V., Lobbia, G.G., Serra, V., Vignola, L., Zenoni, D., Zurlo, V., De Montis, Stefania, Giombolini, Alfonso, Corsaro, Emanuele, and Vaccaro, Gianluca

Published
2023
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3. The advantages of home-care enteral nutrition

Author

De Montis, Stefania, primary, Giombolini, Alfonso, additional, Corsaro, Emanuele, additional, Vaccaro, Gianluca, additional, Andreoli, M., additional, Bertasi, V., additional, Borroni, F., additional, Calzona, A.B., additional, Caravella, G., additional, Crosasso, P., additional, De Montis, S., additional, Ladisa, V., additional, Lobbia, G.G., additional, Serra, V., additional, Vignola, L., additional, Zenoni, D., additional, and Zurlo, V., additional

Published
2023
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5. Short-term Evolution of Nutritional Status in Patients with Idiopathic Pulmonary Fibrosis

Author

Faverio, P, Fumagalli, A, Conti, S, Madotto, F, Bini, F, Harari, S, Mondoni, M, Oggionni, T, Barisione, E, Ceruti, P, Papetti, M, Bodini, B, Caminati, A, Valentino, A, Centanni, S, Lanzi, P, Della Zoppa, M, Crotti, S, Grosso, M, Sukkar, S, Modina, D, Andreoli, M, Nicali, R, Suigo, G, Busnelli, S, Paciocco, G, Lettieri, S, Mantovani, L, Cesana, G, Pesci, A, Luppi, F, Faverio, Paola, Fumagalli, Alessia, Conti, Sara, Madotto, Fabiana, Bini, Francesco, Harari, Sergio, Mondoni, Michele, Oggionni, Tiberio, Barisione, Emanuela, Ceruti, Paolo, Papetti, Maria Chiara, Bodini, Bruno Dino, Caminati, Antonella, Valentino, Angela, Centanni, Stefano, Lanzi, Paola, Della Zoppa, Matteo, Crotti, Silvia, Grosso, Marco, Sukkar, Samir Giuseppe, Modina, Denise, Andreoli, Marco, Nicali, Roberta, Suigo, Giulia, Busnelli, Sara, Paciocco, Giuseppe, Lettieri, Sara, Mantovani, Lorenzo Giovanni, Cesana, Giancarlo, Pesci, Alberto, Luppi, Fabrizio, Faverio, P, Fumagalli, A, Conti, S, Madotto, F, Bini, F, Harari, S, Mondoni, M, Oggionni, T, Barisione, E, Ceruti, P, Papetti, M, Bodini, B, Caminati, A, Valentino, A, Centanni, S, Lanzi, P, Della Zoppa, M, Crotti, S, Grosso, M, Sukkar, S, Modina, D, Andreoli, M, Nicali, R, Suigo, G, Busnelli, S, Paciocco, G, Lettieri, S, Mantovani, L, Cesana, G, Pesci, A, Luppi, F, Faverio, Paola, Fumagalli, Alessia, Conti, Sara, Madotto, Fabiana, Bini, Francesco, Harari, Sergio, Mondoni, Michele, Oggionni, Tiberio, Barisione, Emanuela, Ceruti, Paolo, Papetti, Maria Chiara, Bodini, Bruno Dino, Caminati, Antonella, Valentino, Angela, Centanni, Stefano, Lanzi, Paola, Della Zoppa, Matteo, Crotti, Silvia, Grosso, Marco, Sukkar, Samir Giuseppe, Modina, Denise, Andreoli, Marco, Nicali, Roberta, Suigo, Giulia, Busnelli, Sara, Paciocco, Giuseppe, Lettieri, Sara, Mantovani, Lorenzo Giovanni, Cesana, Giancarlo, Pesci, Alberto, and Luppi, Fabrizio

Published
2023

6. The geomorphology and neotectonics of the Vaalputs Radioactive Waste Disposal Facility site, Namaqualand, South Africa: Palaeoseismological and geodynamic implications.

Author

Andreoli, M. A. G., Knight, J., Durrheim, R. J., and Evans, M.

Subjects
RADIOACTIVE wastes, RADIOACTIVE waste sites, RADIOACTIVE waste disposal, NEOTECTONICS, GEOMORPHOLOGY, WASTE products, FAULT zones, THRUST faults (Geology)
Abstract

The safe disposal of radioactive waste products remains a challenging and controversial issue, yet their burial in a stable geological environment is the option favoured by most countries. Past investigations of the Vaalputs facility in South Africa's semi-arid Bushmanland Plateau demonstrated its suitability for the disposal of low-level, short-lived (<300 years) radioactive waste, but also the need for more data on hazardous seismotectonic and climatic processes for the potential storage of longer-lived spent nuclear fuel. We review and then provide new information on the regional geomorphological and morphotectonic features of the Bushmanland Plateau, focusing on pedogenic features and compressive shear fractures in the trenches excavated over the past two decades. The fractures, provisionally dated between ~75 ka and ~46 ka, resemble east-verging thrust faults of limited horizontal displacement (≤1 m) and die out at depths of 4 m. Having discounted a pedogenic origin, the shear fractures likely represent stress relief structures triggered by the seismogenic reactivation of one of the Quaternary active faults in the area. The most likely candidate is the Santab Fault Zone (SFZ), which has a strike length ≥20 km and a throw of up to ~5 m at its closest point (8 km) to the Vaalputs site. Regional remote sensing and off-site investigations in the Bushmanland Plateau relate the neotectonic episodes at Vaalputs and environs to a late Pleistocene climax of the Namaqualand seismic source zone. This zone is characterised by the Wegener Stress Anomaly, a long-lived ~northwest-southeast oriented compression that, at its apex in the Late Santonian, caused large scale folding and thrusting not only in Bushmanland and parts of central-southern Namibia, but also swept across the entire African plate. [ABSTRACT FROM AUTHOR]

Published
2023
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9. T.03.6 PANENTERIC INVESTIGATION AND SURVEILLANCE IN PATIENTS WITH SHORT BOWEL SYNDROME

Author

Smania, V., primary, Vecchi, M., additional, Costantino, A., additional, Nandi, N., additional, Roggero, P., additional, Norsa, L., additional, Caccialanza, R., additional, Di Sabatino, A., additional, Mengoli, C., additional, Muzio, F., additional, Onida, P., additional, Corradi, E., additional, Cortinovis, F., additional, Gavazzi, C., additional, Mascheroni, A., additional, Redaelli, E., additional, Massironi, S., additional, Viganò, C., additional, Milani, D., additional, Gallitelli, L., additional, Andreoli, M., additional, and Elli, L., additional

Published
2022
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10. Sarcopenia in idiopathic pulmonary fibrosis: a prospective study exploring prevalence, associated factors and diagnostic approach

Author

Faverio, P, Fumagalli, A, Conti, S, Madotto, F, Bini, F, Harari, S, Mondoni, M, Oggionni, T, Barisione, E, Ceruti, P, Papetti, M, Bodini, B, Caminati, A, Valentino, A, Centanni, S, Lanzi, P, Della Zoppa, M, Crotti, S, Grosso, M, Sukkar, S, Modina, D, Andreoli, M, Nicali, R, Suigo, G, Busnelli, S, Paciocco, G, Lettieri, S, Mantovani, L, Cesana, G, Pesci, A, Luppi, F, Faverio, Paola, Fumagalli, Alessia, Conti, Sara, Madotto, Fabiana, Bini, Francesco, Harari, Sergio, Mondoni, Michele, Oggionni, Tiberio, Barisione, Emanuela, Ceruti, Paolo, Papetti, Maria Chiara, Bodini, Bruno Dino, Caminati, Antonella, Valentino, Angela, Centanni, Stefano, Lanzi, Paola, Della Zoppa, Matteo, Crotti, Silvia, Grosso, Marco, Sukkar, Samir Giuseppe, Modina, Denise, Andreoli, Marco, Nicali, Roberta, Suigo, Giulia, Busnelli, Sara, Paciocco, Giuseppe, Lettieri, Sara, Mantovani, Lorenzo Giovanni, Cesana, Giancarlo, Pesci, Alberto, Luppi, Fabrizio, Faverio, P, Fumagalli, A, Conti, S, Madotto, F, Bini, F, Harari, S, Mondoni, M, Oggionni, T, Barisione, E, Ceruti, P, Papetti, M, Bodini, B, Caminati, A, Valentino, A, Centanni, S, Lanzi, P, Della Zoppa, M, Crotti, S, Grosso, M, Sukkar, S, Modina, D, Andreoli, M, Nicali, R, Suigo, G, Busnelli, S, Paciocco, G, Lettieri, S, Mantovani, L, Cesana, G, Pesci, A, Luppi, F, Faverio, Paola, Fumagalli, Alessia, Conti, Sara, Madotto, Fabiana, Bini, Francesco, Harari, Sergio, Mondoni, Michele, Oggionni, Tiberio, Barisione, Emanuela, Ceruti, Paolo, Papetti, Maria Chiara, Bodini, Bruno Dino, Caminati, Antonella, Valentino, Angela, Centanni, Stefano, Lanzi, Paola, Della Zoppa, Matteo, Crotti, Silvia, Grosso, Marco, Sukkar, Samir Giuseppe, Modina, Denise, Andreoli, Marco, Nicali, Roberta, Suigo, Giulia, Busnelli, Sara, Paciocco, Giuseppe, Lettieri, Sara, Mantovani, Lorenzo Giovanni, Cesana, Giancarlo, Pesci, Alberto, and Luppi, Fabrizio

Abstract

Background: Sarcopenia gained importance in the evaluation of patients with chronic respiratory diseases, including idiopathic pulmonary fibrosis (IPF), since it may impact negatively on clinical outcomes. Aim: Aim of this study is to evaluate the prevalence and factors associated with sarcopenia, defined according to the European Working Group on Sarcopenia in Older People 2 (EWGSOP2) 2019 definition, and to evaluate the prevalence of the single criteria that define the EWGSOP2 definition (muscle strength, muscle quantity and physical performance), in a cohort of consecutive patients with IPF prospectively followed up in 9 hospitals in Northern Italy between December 2018 and May 2021. Methods: Enrolled patients underwent an extensive pulmonary and nutritional assessment, including bioelectrical impedance analysis, dynamometry and 4-m gait speed test, both at IPF diagnosis and at 6-month follow-up. Results: Out of the 83 patients (81% males, mean age 72.5 years) with IPF at disease diagnosis enrolled in the study, 19 (22.9%) showed sarcopenia, including 2 (2.4%) with severe sarcopenia, 5 (6.0%) with confirmed sarcopenia and 12 (14.5%) with probable sarcopenia. Sarcopenia was associated with a significantly higher severity of the disease and sedentary lifestyle, while no differences were observed in regards to body mass index, history of weight loss and comorbidities between patients with and without sarcopenia. Out of the 64 patients without sarcopenia at baseline, 16 cases showed alteration of muscle quantity and/or physical performance. In the 51 patients with complete data at 6-month follow-up, there were no cases of severe sarcopenia, 1 case (2.0%) showed confirmed sarcopenia, while the prevalence of probable sarcopenia was 19.6% (10 cases). No differences in regards to antifibrotic treatment received and onset of gastrointestinal side effects were observed between patients with and without sarcopenia at follow-up. Conclusions: The prevalence of sarcopenia in p

Published
2022

13. The advantages of home-care enteral nutrition

Author

De Montis, Stefania, Giombolini, Alfonso, Corsaro, Emanuele, Vaccaro, Gianluca, Andreoli, M., Bertasi, V., Borroni, F., Calzona, A.B., Caravella, G., Crosasso, P., De Montis, S., Ladisa, V., Lobbia, G.G., Serra, V., Vignola, L., Zenoni, D., and Zurlo, V.

Abstract

Home-care Enteral Nutrition (HEN) is used when patients are unable to feed orally, ensuring the correct and complete administration of essential substances for the health of the body. In Italy, a total of 16,400 patients with HEN have been estimated through a survey carried out in 2012 and the 2005–2012 period saw a significant rise in the number of people needing artificial nutrition. A consensus work involving some of the major Italian HEN experts and stakeholders has been carried out using the Nominal Focus Group technique and Delphi method to discuss HEN and explore the general clinical advantages of commercial preparation. The resulting document presented here focuses on bolus administration with commercial preparations and consequently on the potential advantages of a new bolus administration with a 250 ml Smartflex technology, which simplifies administration by allowing the direct connection of the bottle to the feeding tube.This work has highlighted how bolus administration with commercial preparations can represent a valid tool for the delivery of HEN, improving QoL and psychological well-being, limiting the impact of the disease on social life and eventually bringing pharmaco-economic benefits for the national health system due to waste reduction of both product and devices.

Published
2023
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14. Nutritional assessment in idiopathic pulmonary fibrosis: a prospective multicentre study

Author

Faverio, P, Fumagalli, A, Conti, S, Madotto, F, Bini, F, Harari, S, Mondoni, M, Oggionni, T, Barisione, E, Ceruti, P, Papetti, M, Bodini, B, Caminati, A, Valentino, A, Centanni, S, Noè, D, Della Zoppa, M, Crotti, S, Grosso, M, Sukkar, S, Modina, D, Andreoli, M, Nicali, R, Suigo, G, De Giacomi, F, Busnelli, S, Cattaneo, E, Mantovani, L, Cesana, G, Pesci, A, Luppi, F, Faverio, P, Fumagalli, A, Conti, S, Madotto, F, Bini, F, Harari, S, Mondoni, M, Oggionni, T, Barisione, E, Ceruti, P, Papetti, M, Bodini, B, Caminati, A, Valentino, A, Centanni, S, Noè, D, Della Zoppa, M, Crotti, S, Grosso, M, Sukkar, S, Modina, D, Andreoli, M, Nicali, R, Suigo, G, De Giacomi, F, Busnelli, S, Cattaneo, E, Mantovani, L, Cesana, G, Pesci, A, and Luppi, F

Abstract

Background. Nutritional status (NS) impacts on quality of life and prognosis of patients with respiratory diseases including idiopathic pulmonary fibrosis (IPF). However, there is a lack of studies performing an extensive nutritional assessment of IPF patients. This study aims to investigate the NS and to identify nutritional phenotypes in a cohort of IPF patients at diagnosis. Methods. Patients underwent a thorough pulmonary and nutritional evaluation including questionnaires on NS and physical activity, anthropometry, body impedence, dynamometry, 4- meter gait speed and blood tests. Results. 90 IPF patients (78.9% males, mean age 72.7 years) were enrolled. The majority of patients were classified as Gender-Age-Physiology Index stage 2 (47, 52.2%) with an inactive lifestyle according to International Physical Activity Questionnaire score (39, 43.3%) and had mean forced vital capacity and diffusing capacity for carbon monoxide 86.5% and 54.2%, respectively. In regards to nutritional phenotypes, the majority of patients were normally nourished (67.8%, 95% Confidence Interval (CI):58.6-77.7), followed by non-sarcopenic obese (25.3%, 95%CI:16.1-35.2), sarcopenic (4.6%, 95%CI:0.0-14.5) and sarcopenic obese (2.3%, 95%CI:0.0-12.2). Among normally nourished, 49.2% showed early signs of nutritional and physical performance alterations, including body mass index≥ 30 in 4.3%, history of weight loss≥ 5% in 11.9%, reduction of gait speed and hand grip strength in 11.9% and 35.6%, respectively. Low vitamin D values were observed in 56.3% of cases. Conclusions. IPF patients at diagnosis are mainly normally nourished and obese, but early signs of nutritional and physical performance impairment can already be identified at this stage.

Published
2021

15. Discovery of a 25-cm asteroid clast in the giant Morokweng impact crater, South Africa

Author

Maier, W. D., Andreoli, M. A. G., McDonald, I., Higgins, M. D., Boyce, A. J., Shukolyukov, A., Lugmair, G. W., Ashwal, L. D., Graser, P., Ripley, E. M., and Hart, R. J.

Subjects
Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

Author(s): W. D. Maier (corresponding author) [1, 2]; M. A. G. Andreoli [3, 4]; I. McDonald [5]; M. D. Higgins [1]; A. J. Boyce [6]; A. Shukolyukov [7]; G. W. [...]

Published
2006
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18. Introduction and methods of the evidence-based guidelines for the diagnosis and management of autism spectrum disorder by the Italian National Institute of Health

Author

Morgano, G. P., Fulceri, F., Nardocci, F., Barbui, C., Ostuzzi, G., Papola, D., Fatta, L. M., Fauci, A. J., Coclite, D., Napoletano, A., De Crescenzo, F., D'Alo, G. L., Amato, L., Cinquini, M., Iannone, P., Schunemann, H. J., Scattoni, M. L., Arduino, M., Bellosio, C., Biasci, S., Buono, S., Cappa, C., Cordo, C., Di Tommaso, E., Duff, C. M., Felici, C., Massagli, A., Molteni, M., Reali, L., Tancredi, R., Valeri, G., Venturini, L., Zuddas, A., Andreoli, M., Bergamin, C., Bertelli, M., Catania, D., Cavagnola, R., Cirrincione, P., Corti, S., Crognale, M., Faggioli, R., Giogoli, A. M., Grittani, S., Keller, R., Pace, P., Politi, P., Starace, F., Valenti, M., Balduzzi, S., Basile, M., Cruciani, F., D'Amico, R., Davoli, M., Lorenzo, M. G., Minozzi, S., Mitrova, Z., Moschetti, I., Pistotti, V., Saulle, R., and Vecchi, S.

Subjects
Adult, Male, Evidence-based practice, Adolescent, Autism Spectrum Disorder, Psychological intervention, Guideline, Recommendations, lcsh:Computer applications to medicine. Medical informatics, 03 medical and health sciences, 0302 clinical medicine, Diagnosis, medicine, Humans, 030212 general & internal medicine, Patient Reported Outcome Measures, Autism Spectrum disorder, GRADE approach, Healthcare decision, Italian National Institute of health, Italian national guidelines system, Treatment, Grading (education), Child, Medical education, Evidence-Based Medicine, Research, Public Health, Environmental and Occupational Health, Conflict of interest, Stakeholder, Italy, Quality of Life, Practice Guidelines as Topic, General Medicine, Evidence-based medicine, medicine.disease, Autism spectrum disorder, ComputingMilieux_COMPUTERSANDSOCIETY, lcsh:R858-859.7, Psychology, 030217 neurology & neurosurgery
Abstract

Background Autism Spectrum Disorder (ASD) is a neuro-developmental disorder that affects communication and behavior with a prevalence of approximately 1% worldwide. Health outcomes of interventions for ASD are largely Participant Reported Outcomes (PROs). Specific guidelines can help support the best care for people with ASD to optimize these health outcomes but they have to adhere to standards for their development to be trustworthy. Objective The goal of this article is to describe the new methodological standards of the Italian National Institute of Health and novel aspects of this guideline development process. This article will serve as a reference standard for future guideline development in the Italian setting. Methods We applied the new standards of the Italian National Institute of Health to the two guidelines on diagnosis and management of children/adolescents and adults with ASD, with a focus on the scoping, panel composition, management of conflict of interest, generation and prioritization of research questions, early stakeholders’ involvement, and PROs. Recommendations are based on the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Evidence-to-Decision frameworks. Results Following a public application process, the ISS established two multidisciplinary panels including people with ASD and/or their caregivers. Seventy-nine research questions were identified as potentially relevant for the guideline on children and adolescents with ASD and 31 for the one on adults with ASD. Questions deemed to have the highest priority were selected for inclusion in the guidelines. Other stakeholders valued their early involvement in the process which will largely focus on PROs. The panels then successfully piloted the development of recommendations using the methodological standards and process set by the ISS with a focus on PROs. Conclusions In this article, we describe the development of practice guidelines that focus on PROs for the diagnosis and management of ASD based on novel methods for question prioritization and stakeholder involvement. The recommendations allow for the adoption or adaptation to international settings.

Published
2020

24. Erratum to: tDCS application over the STG improves the ability to recognize and appreciate elements involved in humor processing (Experimental Brain Research, (2017), 235, 6, (1843-1852), 10.1007/s00221-017-4932-5)

Author

Manfredi M., Manfredi, M, Proverbio, A, Donate, A, Vieira, S, Comfort, W, De Araujo Andreoli, M, Boggio, P, Manfredi M., Proverbio A. M., Donate A. P. G., Vieira S. M. G., Comfort W. E., De Araujo Andreoli M., Boggio P. S., Manfredi M., Manfredi, M, Proverbio, A, Donate, A, Vieira, S, Comfort, W, De Araujo Andreoli, M, Boggio, P, Manfredi M., Proverbio A. M., Donate A. P. G., Vieira S. M. G., Comfort W. E., De Araujo Andreoli M., and Boggio P. S.

Abstract

The original version of this article contained an error in two references (listed below) for Bonda et al. (1996). Bonda E, Ostry D, Evans A (1996a) Specific involvement of human parietal systems in the perception of biological motion and the amygdala. J Neurosci 76(11):3737-3744 Bonda E, Petrides M, Ostry D, Evans A (1996b) Specific involvement of human parietal systems and the amygdala in the perception of biological motion. J Neurosci 16:3737-3744 They should be deleted and substituted with just one paper whose the correct reference is: Bonda E, Petrides M, Ostry D, Evans A (1996) Specific involvement of human parietal systems and the amygdala in the perception of biological motion. J Neurosci 16(11):3737-3744.

Published
2017

27. PB2269 PARENTERAL NUTRITION AND ACUTE GVHD IN HEMATOPOIETIC STEM CELLS TRANSPLANTATION: A PROSPECTIVE OBSERVATIONAL COHORT STUDY

Author

Arena, F., primary, Morello, E., additional, Bertocchi, G., additional, Malagola, M., additional, Samarani, E., additional, Bertulli, A., additional, Farina, M., additional, Gandolfi, L., additional, Polverelli, N., additional, Turra, A., additional, Cattina, F., additional, Andreoli, M., additional, and Russo, D., additional

Published
2019
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28. PS1540 MULTIPARAMETRIC PREDICTIVE SCORE FOR GRAFT VERSUS HOST DISEASE (GVHD) IN PATIENTS SUBMITTED TO ALLOGENEIC STEM CELLS TRANSPLANTATION (SCT)

Author

Turra, A., primary, Polverelli, N., additional, Corvini, F., additional, Morello, E., additional, Malagola, M., additional, Arena, F., additional, Andreoli, M., additional, Bertulli, A., additional, Farina, M., additional, Cattina, F., additional, Rambaldi, B., additional, Gandolfi, L., additional, Zollner, T., additional, Buttini, E. Accorsi, additional, Bernardi, S., additional, Zanaglio, C., additional, Foroni, C., additional, Re, F., additional, and Russo, D., additional

Published
2019
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30. Assessment of the incremental diagnostic value of florbetapir F 18 imaging in patients with cognitive impairment: The incremental diagnostic value of amyloid PET with [18F]-florbetapir (INDIA-FBP) study

Author

Boccardi, M, Altomare, D, Ferrari, C, Festari, C, Guerra, U, Paghera, B, Pizzocaro, C, Lussignoli, G, Geroldi, C, Zanetti, O, Cotelli, M, Turla, M, Borroni, B, Rozzini, L, Mirabile, D, Defanti, C, Gennuso, M, Prelle, A, Gentile, S, Morandi, A, Vollaro, S, Volta, G, Bianchetti, A, Conti, M, Cappuccio, M, Carbone, P, Bellandi, D, Abruzzi, L, Bettoni, L, Villani, D, Raimondi, M, Lanari, A, Ciccone, A, Facchi, E, Di Fazio, I, Rozzini, R, Boffelli, S, Manzoni, L, Salvi, G, Cavaliere, S, Belotti, G, Avanzi, S, Pasqualetti, P, Muscio, C, Padovani, A, Frisoni, G, Antelmi, L, Galluzzi, S, Pievani, M, Redolfi, A, Tarallo, A, Arora, A, Bertocchi, M, Chito, E, Moretti, D, Giubbini, R, Rodella, C, Camoni, L, Massetti, V, Andreoli, M, Bellelli, G, Fascendini, S, Mattioli, F, Turco, R, Vezzadini, G, Raimondi, V, Mondini, S, Zanacchi, E, Grigolo, M, Pezzini, A, Bilotti, G, Bigni, B, Zavarise, P, Ngonga, G, Anzola, G, Turrone, R, Guizzetti, G, Zanetti, M, Boccardi M., Altomare D., Ferrari C., Festari C., Guerra U. P., Paghera B., Pizzocaro C., Lussignoli G., Geroldi C., Zanetti O., Cotelli M. S., Turla M., Borroni B., Rozzini L., Mirabile D., Defanti C., Gennuso M., Prelle A., Gentile S., Morandi A., Vollaro S., Volta G. D., Bianchetti A., Conti M. Z., Cappuccio M., Carbone P., Bellandi D., Abruzzi L., Bettoni L., Villani D., Raimondi M. C., Lanari A., Ciccone A., Facchi E., Di Fazio I., Rozzini R., Boffelli S., Manzoni L., Salvi G. P., Cavaliere S., Belotti G., Avanzi S., Pasqualetti P., Muscio C., Padovani A., Frisoni G. B., Antelmi L., Galluzzi S., Pievani M., Redolfi A., Tarallo A., Arora A., Bertocchi M., Chito E., Moretti D. V., Giubbini R., Rodella C., Camoni L., Massetti V., Andreoli M., Bellelli G., Fascendini S., Mattioli F., Turco R., Vezzadini G., Raimondi V., Mondini S., Zanacchi E. C., Grigolo M., Pezzini A., Bilotti G., Bigni B., Zavarise P., Ngonga G., Anzola G. P., Turrone R., Guizzetti G., Zanetti M., Boccardi, M, Altomare, D, Ferrari, C, Festari, C, Guerra, U, Paghera, B, Pizzocaro, C, Lussignoli, G, Geroldi, C, Zanetti, O, Cotelli, M, Turla, M, Borroni, B, Rozzini, L, Mirabile, D, Defanti, C, Gennuso, M, Prelle, A, Gentile, S, Morandi, A, Vollaro, S, Volta, G, Bianchetti, A, Conti, M, Cappuccio, M, Carbone, P, Bellandi, D, Abruzzi, L, Bettoni, L, Villani, D, Raimondi, M, Lanari, A, Ciccone, A, Facchi, E, Di Fazio, I, Rozzini, R, Boffelli, S, Manzoni, L, Salvi, G, Cavaliere, S, Belotti, G, Avanzi, S, Pasqualetti, P, Muscio, C, Padovani, A, Frisoni, G, Antelmi, L, Galluzzi, S, Pievani, M, Redolfi, A, Tarallo, A, Arora, A, Bertocchi, M, Chito, E, Moretti, D, Giubbini, R, Rodella, C, Camoni, L, Massetti, V, Andreoli, M, Bellelli, G, Fascendini, S, Mattioli, F, Turco, R, Vezzadini, G, Raimondi, V, Mondini, S, Zanacchi, E, Grigolo, M, Pezzini, A, Bilotti, G, Bigni, B, Zavarise, P, Ngonga, G, Anzola, G, Turrone, R, Guizzetti, G, Zanetti, M, Boccardi M., Altomare D., Ferrari C., Festari C., Guerra U. P., Paghera B., Pizzocaro C., Lussignoli G., Geroldi C., Zanetti O., Cotelli M. S., Turla M., Borroni B., Rozzini L., Mirabile D., Defanti C., Gennuso M., Prelle A., Gentile S., Morandi A., Vollaro S., Volta G. D., Bianchetti A., Conti M. Z., Cappuccio M., Carbone P., Bellandi D., Abruzzi L., Bettoni L., Villani D., Raimondi M. C., Lanari A., Ciccone A., Facchi E., Di Fazio I., Rozzini R., Boffelli S., Manzoni L., Salvi G. P., Cavaliere S., Belotti G., Avanzi S., Pasqualetti P., Muscio C., Padovani A., Frisoni G. B., Antelmi L., Galluzzi S., Pievani M., Redolfi A., Tarallo A., Arora A., Bertocchi M., Chito E., Moretti D. V., Giubbini R., Rodella C., Camoni L., Massetti V., Andreoli M., Bellelli G., Fascendini S., Mattioli F., Turco R., Vezzadini G., Raimondi V., Mondini S., Zanacchi E. C., Grigolo M., Pezzini A., Bilotti G., Bigni B., Zavarise P., Ngonga G., Anzola G. P., Turrone R., Guizzetti G., and Zanetti M.

Abstract

IMPORTANCE Cerebral amyloidosis is a key abnormality in Alzheimer disease (AD) and can be detected in vivo with positron emission tomography (PET) ligands. Although amyloid PET has clearly demonstrated analytical validity, its clinical utility is debated. OBJECTIVE To evaluate the incremental diagnostic value of amyloid PET with florbetapir F 18 in addition to the routine clinical diagnostic assessment of patients evaluated for cognitive impairment. DESIGN, SETTING, AND PARTICIPANTS The Incremental Diagnostic Value ofAmyloid PET With [18F]-Florbetapir (INDIA-FBP) Study is a multicenter study involving 18 AD evaluation units from eastern Lombardy, Northern Italy, 228 consecutive adults with cognitive impairmentwere evaluated for AD and other causes of cognitive decline, with a prescan diagnostic confidence of AD between 15%and 85%. Participants underwent routine clinical and instrumental diagnostic assessment. A prescan diagnosiswas made, diagnostic confidencewas estimated, and drug treatmentwas provided. At the time of thisworkup, an amyloid PET/computed tomographic scanwas performed, and the resultwas communicated to physicians afterworkup completion. Physicianswere asked to review the diagnosis, diagnostic confidence, and treatment after the scan. The studywas conducted from August 5, 2013, to December 31, 2014. MAIN OUTCOMES AND MEASURES Primary outcomeswere prescan to postscan changes of diagnosis, diagnostic confidence, and treatment. RESULTS Of the 228 participants, 107 (46%) were male; mean (SD) age was 70.5 (7) years. Diagnostic change occurred in 46 patients (79%) having both a previous diagnosis of AD and an amyloid-negative scan (P < .001) and in 16 (53%) of those with non-AD diagnoses and an amyloid-positive scan (P < .001). Diagnostic confidence in AD diagnosis increased by 15.2%in amyloid-positive (P < .001; effect size Cohen d = 1.04) and decreased by 29.9%in amyloid-negative (P < .001; d = -1.19) scans. Acetylcholinesterase inhibitors and

Published
2016

33. A long term baseline and variability of natural radionuclides in groundwater at the Vaalputs low-level radioactive waste disposal facility, Namaqualand, South Africa: regional implications.

Author

Pretorius, H. C. F., Tredoux, M., Andreoli, M. A. G., and Vermeulen, P. D.

Subjects
RADIOACTIVE waste sites, RADIOACTIVE waste disposal, LEACHING, RADIOISOTOPES, GROUNDWATER, RADIOACTIVE wastes, SEDIMENTARY rocks
Abstract

Vaalputs is the only South African nuclear waste disposal facility; it is licensed to dispose of low and intermediate level radioactive waste. Possible disposal of long-lived waste, potentially including spent fuel rods, prompted a study to establish a baseline of naturally-occurring radionuclides from the U and Th decay chains in the groundwater of Vaalputs. This baseline was created by investigating a dataset containing 25 years of analyses of the groundwater at the Vaalputs site. The behaviour over time, of 23 radionuclides in groundwater samples from 13 annually and three quarterly sampled boreholes, was evaluated and integrated in order to establish changing trends in the activities of radionuclides, the relative contributions of individual radionuclides to total radiation levels and how these were influenced by groundwater conditions. 238U levels showed a natural anomaly in the near-field of the disposal site that was attributed to the underlying basement rocks (granites) which are anomalously enriched in U. A set of duplicate samples from 2009 determined that the activity ratio of 234U/238U in the groundwater of Vaalputs is 4.1; this is ascribed to more rapid leaching of 234U relative to 238U, because of increased crystal structural damage around sites surrounding 234U atoms. High levels of 226Ra, unsupported by 238U, were found in groundwater from boreholes on the western side of the property: this groundwater yielded low values for 234U/238U, lower pH and stronger oxidizing conditions than groundwater from the rest of the area. The absence of overlying sedimentary rocks, which tend to ameliorate the effects of high radiation from granites by absorption, is suggested as the reason for the different geochemical conditions of the groundwater from boreholes in the west. This suggestion may apply to those boreholes elsewhere in Namaqualand with low published concentrations of 238U, but exceptionally high levels of α -and β-emitters. 232Th and its daughter radionuclides yielded radiation levels far below the guideline of 1 Bq.L-1 specified by the World Health Organization; this result is in line with the known low mobility of Th in groundwater systems. [ABSTRACT FROM AUTHOR]

Published
2020
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36. A multi-analytical approach for the study of the pigments used in the wall paintings from a building complex on the Caelian Hill (Rome)

Author

Fermo, P, Piazzalunga, A, de Vos, M, Andreoli, M, Andreoli, M., PIAZZALUNGA, ANDREA, Fermo, P, Piazzalunga, A, de Vos, M, Andreoli, M, Andreoli, M., and PIAZZALUNGA, ANDREA

Abstract

In the present study, shards from Roman wall paintings (from the end of the first century to the fourth century A.D.) decorating the domus below the Basilica of SS. John and Paul on the Caelian Hill (Rome), were analyzed in order to identify the pigments used. The analytical techniques employed for the characterization of the pigments were the scanning electron microscope coupled with an energy dispersive spectrometer (SEM-EDS) and infrared spectroscopy (ATR and micro ATR). While SEM-EDS allowed to perform a qualitative analysis of the material, by FT-IR chemical species have been identified. The pigments identified were those mentioned in the literature for the Imperial Roman fresco painting: different types of ochre (yellow and red), mixtures containing lead, green earths and precious pigments such as cinnabar and Egyptian blue. They were often used as mixtures and the use of the most valuable pigments (cinnabar and Egyptian blue) were found in the most ancient rooms

Published
2013

37. Mathematica and LaTeX Integration

Author

Andreoli M

Subjects
Theoretical computer science, Computer science, Programming language, Object (computer science), computer.software_genre, Expression (mathematics), Symbol (programming), ComputingMethodologies_SYMBOLICANDALGEBRAICMANIPULATION, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, Perl, Macro, Algebraic expression, Graphics, computer, Semicolon, computer.programming_language
Abstract

This document is about Mathex, a software package that allows to embed Mathematica © macro expressions into a LaTeX document, combining together the power of the two systems. It works in this way: when You click F2 on your preferred editor, before of the TeX to PDF conversion, a pre-processor (written in the PERL language) call Mathematica, do the computation globally (i.e. treating the file as a single program) and replaces the macros in the final TeX. The macros should be inserted between the two conventional simbols , and can contain every valid Mathematica’s expression, or more espressions, separated by semicolon. As every expression and every graphics object get created everytime on-the-fly, the process can be slow.

Published
2016
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38. tDCS application over the STG improves the ability to recognize and appreciate elements involved in humor processing

Author

Manfredi, M, Proverbio, A, Gonçalves Donate, A, Macarini Gonçalves Vieira, S, Comfort, W, de Araújo Andreoli, M, Boggio, P, MANFREDI, MIRELLA, PROVERBIO, ALICE MADO, Boggio, P., Manfredi, M, Proverbio, A, Gonçalves Donate, A, Macarini Gonçalves Vieira, S, Comfort, W, de Araújo Andreoli, M, Boggio, P, MANFREDI, MIRELLA, PROVERBIO, ALICE MADO, and Boggio, P.

Abstract

The superior temporal gyrus (STG) has been found to play a crucial role in the recognition of actions and facial expressions and may, therefore, be critical for the processing of humorous information. Here we investigated whether tDCS application to the STG would modulate the ability to recognize and appreciate the comic element in serious and comedic situations of misfortune. To this aim, the effects of different types of tDCS stimulation on the STG were analyzed during a task in which the participants were instructed to categorize various misfortunate situations as “comic” or “not comic”. Participants underwent three different tDCS conditions: Anodal-right/Cathodal-left; Cathodal-right/Anodal-left; Sham. Images depicting people involved in accidents were grouped into three categories based on the facial expression of the victim: angry or painful (Affective); bewildered and funny (Comic); and images that did not contain the victim’s face (No Face). An improvement in mean reaction times in response to both the Comic and No Face stimuli was observed following Anodal-left/Cathodal-right stimulation when compared to sham stimulation. This suggests that this stimulation type reduced the reaction times to socio-emotional complex scenes, regardless of facial expression. The Anodal-right/Cathodal-left stimulation reduced the mean reaction times for Comic stimuli only, suggesting that specifically the right STG may be involved in facial expression recognition and in the appreciation of the comic element in misfortunate situations. These results suggest a functional hemispheric asymmetry in STG response to social stimuli: the left STG might have a role in a general comprehension of social complex situations, while the right STG may be involved in the ability to recognize and integrate specific emotional aspects in a complex scene.

Published
2017

39. Lessons learned from 200 consecutive primary liver transplantations with left lateral segment split grafts

Author

Corno, V, Dezza, M, Lucianetti, A, Pinelli, D, Codazzi, D, Guizzetti, M, Zambelli, M, Melzi, M, Stroppa, P, Candusso, M, Bravi, M, Andreoli, M, Alberti, D, Torre, G, Colledan, M, Corno V, Dezza MC, Lucianetti A, Pinelli D, Codazzi D, Guizzetti M, Zambelli M, Melzi ML, Stroppa P, Candusso M, Bravi M, Andreoli M, Alberti D, Torre G, Colledan M, Corno, V, Dezza, M, Lucianetti, A, Pinelli, D, Codazzi, D, Guizzetti, M, Zambelli, M, Melzi, M, Stroppa, P, Candusso, M, Bravi, M, Andreoli, M, Alberti, D, Torre, G, Colledan, M, Corno V, Dezza MC, Lucianetti A, Pinelli D, Codazzi D, Guizzetti M, Zambelli M, Melzi ML, Stroppa P, Candusso M, Bravi M, Andreoli M, Alberti D, Torre G, and Colledan M

Published
2007

40. Long term outcome of pediatric split liver transplantation from donors aged more than 50 years

Author

Guizzetti, M, Sonzogni, A, Petz, W, Zambelli, M, Lucianetti, A, Pinelli, D, Corno, V, Maldini, G, Bezzo, R, Giovanelli, M, Dezza, M, Andreoli, M, Torre, G, Colledan, M, Guizzetti M, Sonzogni A, Petz W, Zambelli M, Lucianetti A, Pinelli D, Corno V, Maldini G, Bezzo R, Giovanelli M, Dezza MC, Andreoli M, Torre G, Colledan M, Guizzetti, M, Sonzogni, A, Petz, W, Zambelli, M, Lucianetti, A, Pinelli, D, Corno, V, Maldini, G, Bezzo, R, Giovanelli, M, Dezza, M, Andreoli, M, Torre, G, Colledan, M, Guizzetti M, Sonzogni A, Petz W, Zambelli M, Lucianetti A, Pinelli D, Corno V, Maldini G, Bezzo R, Giovanelli M, Dezza MC, Andreoli M, Torre G, and Colledan M

Published
2007

41. Liver transplants in children: The 8 years experience in Bergamo

Author

Torre, G, Melzi, M, Stroppa, P, Candusso, M, Bravi, M, Bosisio, M, Andreoli, M, Sonzogni, A, Colledan, M, Lucinetti, A, Corno, V, Alberti, D, Spotti, A, Nacoti, M, Maldini, G, Torre G, Melzi ML, Stroppa P, Candusso M, Bravi M, Bosisio M, Andreoli M, Sonzogni A, Colledan M, Lucinetti A, Corno V, Alberti D, Spotti A, Nacoti M, Maldini G, Torre, G, Melzi, M, Stroppa, P, Candusso, M, Bravi, M, Bosisio, M, Andreoli, M, Sonzogni, A, Colledan, M, Lucinetti, A, Corno, V, Alberti, D, Spotti, A, Nacoti, M, Maldini, G, Torre G, Melzi ML, Stroppa P, Candusso M, Bravi M, Bosisio M, Andreoli M, Sonzogni A, Colledan M, Lucinetti A, Corno V, Alberti D, Spotti A, Nacoti M, and Maldini G

Published
2006

42. Assessing the effectiveness of alternative designs of greening measures. The case of Tuscany region

Author

Bartolini, F., Andreoli, M., Gava, O., and Brunori, G.

Subjects
agricultural land, cost effectiveness analysis, rural areas, design, urban areas, payment basis, crops, sustainability, environmental impact, farmers' attitudes, mathematical models, agricultural land, cost effectiveness analysis, crops, design, environmental impact, farmers' attitudes, mathematical models, payment basis, policy, rural areas, sustainability, urban areas, policy
Published
2015

43. Present denudation rates at selected sections of the South African escarpment and the elevated continental interior based on cosmogenic He-3 and Ne-21

Author

Kounov, A., Niedermann, S., de Wit, M. J., Andreoli, M., Erzinger, J., VIOLA, GIULIO, Kounov, A., Niedermann, S., de Wit, M. J., Viola, Giulio, Andreoli, M., and Erzinger, J.

Subjects
Denudation rate, Cosmogenic isotopes, Geomorphology
Abstract

Measurements of cosmogenic 3He and 21Ne concentrations in dolerite and quartzite samples from selected sites across the South African coastal escarpment and the interior plateau provide valuable estimates of the short-term (i.e., a few hundred thousand years) denudation rates. Present-day denudation rates at the summit of the escarpment and on the inland plateau are more than an order of magnitude lower than those in the Cretaceous. Values between 1.0 and 2.1 m/Ma obtained from resistant quartzite samples and between 1.5 and 3 m/Ma from dolerite sills suggest a strong lithology control on the erosion. The observed patterns of denudation across different landform sites on the high plateau and along its flanking escarpment suggest that the morphology of the sampling sites together with the local climate conditions have controlled the denudation processes.

Published
2007

44. Liver transplants in children: The 8 years experience in Bergamo

Author

Torre, G., Melzi, Ml, Stroppa, P., Candusso, M., Bravi, M., Bosisio, M., Andreoli, M., aurelio sonzogni, Colledan, M., Lucinetti, A., Corno, V., Alberti, D., Spotti, A., Nacoti, M., Maldini, G., Torre, G, Melzi, M, Stroppa, P, Candusso, M, Bravi, M, Bosisio, M, Andreoli, M, Sonzogni, A, Colledan, M, Lucinetti, A, Corno, V, Alberti, D, Spotti, A, Nacoti, M, and Maldini, G

Subjects
Transplantation, Hepatology, Gastroenterology, Surgery
Published
2006

47. Avaliação das propriedades do Ba0,50Sr0,50Co0,80Fe0,20O3-d para células a combustível de óxido sólido de temperatura intermediária obtido pelo método citratos-EDTA

Author

Bonturim, E., Vargas, R. A., Andreoli, M., and Seo, E. S. M.

Subjects
cathode, ITSOFC, método dos citratos-EDTA, citrate-EDTA method, perovskita, cátodo, perovskite
Abstract

Ba0,50Sr0,50Co0,80Fe0,20O3-d (BSCF) apresenta propriedades físicas, químicas e microestruturais adequadas para compor o cátodo de uma célula a combustível de óxido sólido de temperatura intermediária (ITSOFC). Este trabalho tem por objetivo a síntese e a caracterização do BSCF obtido pelo método dos citrados-EDTA. Os resultados obtidos por difração de raios X (DRX) indicaram fases secundárias para o material calcinado a 700 e 800 ºC e fase única com estrutura cristalina do tipo perovskita para 900 ºC. As micrografias obtidas por microscopia eletrônica de varredura dos particulados evidenciou a formação de aglomerados de tamanho < 20 µm. A análise dilatométrica dos compactos indicou a temperatura de sinterabilidade ~ 1050 ºC. Os resultados de DRX das cerâmicas sinterizadas evidenciaram a presença de fase única perovskita. As micrografias dos sinterizados confirmaram a formação de maior porosidade nas amostras sinterizadas a 1000 °C /1 h, conformadas com pó calcinado a 900 °C. Ba0.50Sr0.50Co0.80Fe0.20O3-d (BSCF) presents physical, chemical and microstructural properties suitable to form the cathode of Intermediate Temperature Solid Oxide Fuel Cell (ITSOFC). This work aims the synthesis and characterization of BSCF, obtained by the citrate-EDTA method. The X-ray diffraction results indicate secondary phases for the material calcined at 700 and 800 °C and single phase with perovskite crystalline structure at 900 °C. The SEM-FEG particles micrographs show the formation of < 20 µm clusters. The dilatometric analysis of pellets indicates the sintering temperature at ~ 1050 °C. XRD results of the sintered samples show perovskite single phase. The SEM micrographs confirmed the formation of higher porosity in the samples sintered at 1000 °C/1 h using powders calcined at 900 °C.

Published
2013

48. GTP is an allosteric modulator of the interaction between the guanylate-binding protein 1 and the prosurvival kinase PIM1

Author

Persico, M, Petrella, L, Orteca, N, Di Dato, A, Mariani, M, Andreoli, M, De Donato, M, Scambia, Giovanni, Novellino, E, Ferlini, C, Fattorusso, C., Scambia, Giovanni (ORCID:0000-0003-2758-1063), Persico, M, Petrella, L, Orteca, N, Di Dato, A, Mariani, M, Andreoli, M, De Donato, M, Scambia, Giovanni, Novellino, E, Ferlini, C, Fattorusso, C., and Scambia, Giovanni (ORCID:0000-0003-2758-1063)

Abstract

GBP1 and PIM1 are known to interact with a molar ratio 1:1. GBP1:PIM1 binding initiates a signaling pathway that induces resistance to common chemotherapeutics such as paclitaxel. Since GBP1 is a large GTPase which undergoes conformational changes in a nucleotide-dependent manner, we investigated the effect of GTP/GDP binding on GBP1:PIM1 interaction by using computational and biological studies. It resulted that only GTP decreases the formation of the GBP1:PIM1 complex through an allosteric mechanism, putting the bases for the identification of new compounds potentially able to revert resistance to paclitaxel.

Published
2015

49. Cosmogenic 21Ne and 10Be reveal a more than 2 Ma alluvial fan flanking the Cape Mountains, South Africa

Author

Kounov, A, Niedermann, S, De Wit, Maarten, Codilean, Alexandru T, Viola, G, Andreoli, M, Christl, M, Kounov, A, Niedermann, S, De Wit, Maarten, Codilean, Alexandru T, Viola, G, Andreoli, M, and Christl, M

Abstract

Cosmogenic 21Ne and 10Be analyses across a subhorizontal fossil alluvial fan flanking the Cape Mountains near Laingsburg (Western Cape, South Africa) indicate a formation age for this fan of at least 2 Ma. Maximum erosion rates obtained from samples of quartzite ridges protruding through the fan alluvium deposits are very low (<~0.4 m/Ma) and analytically indistinguishable from those derived from pebbles from the fan surface (<~1.5 m/Ma). Our results are consistent with the low denudation rates obtained from other cosmogenic nuclide analyses and predicted by apatite fission-track and offshore sedimentation analyses for southern Africa during the Cenozoic. They integrate already existing substantial evidence to show that relative tectonic stability has prevailed across southern Africa throughout this period, and that the present-day large-scale topography is largely inherited from the Cretaceous and has been only minimally resculptured by denudation during the Cenozoic.

Published
2015

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