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20. Role of body mass index in the prediction of all cause mortality in over 62000 men and women. The Italian RIFLE Pooling Project

Author

SECCARECCIA F, LANTI M, MENOTTI A, SCANGA M, THE RIFLE RESEARCH GROUP, FARCHI G, CONTI S, MARENCO G, FALCHERO M, FERRARIO M, CESANA GC, TENCONI MT, MUSSI A, DOBRILLA G, DE PETRIS G, ANGELINI GP, OCKOLICSANYI L, TOSO S, AMBROSIO GB, BITTOLO BON G, ALESSANDRINI P, FERUGLIO GA, VANUZZO D, CARULLI N, SALVIOLI GF, GADDI A, D'ADDARO S, ALVISI V, BUZZELLI GP, GIACCHI M, LAURENZI M, SPAGNOLO A, RICCI G, ANTONINI R, ANGELICO F, LALLONI L, ATTILI AF, URBINATI GC, GIAMPAOLI S, MANCINI M, PANICO S, FARINARO E, ALBANO O, MISCIAGNA G, MUNTONI S, STABILINI L, AVELLONE G, DI GARBO G., DEVOTI, Gabriele, Seccareccia, F, Lanti, M, Menotti, A, Scanga, M, THE RIFLE RESEARCH, Group, Farchi, G, Conti, S, Marenco, G, Falchero, M, Ferrario, M, Cesana, Gc, Tenconi, Mt, Mussi, A, Devoti, Gabriele, Dobrilla, G, DE PETRIS, G, Angelini, Gp, Ockolicsanyi, L, Toso, S, Ambrosio, Gb, BITTOLO BON, G, Alessandrini, P, Feruglio, Ga, Vanuzzo, D, Carulli, N, Salvioli, Gf, Gaddi, A, D'Addaro, S, Alvisi, V, Buzzelli, Gp, Giacchi, M, Laurenzi, M, Spagnolo, A, Ricci, G, Antonini, R, Angelico, F, Lalloni, L, Attili, Af, Urbinati, Gc, Giampaoli, S, Mancini, M, Panico, S, Farinaro, E, Albano, O, Misciagna, G, Muntoni, S, Stabilini, L, Avellone, G, and DI GARBO, G.

Published
1998

22. Electrocardiographic Minnesota Code findings predicting short-term mortality in asymptomatic subjects. The Italian RIFLE Pooling Project (Risk Factors and Life Expectancy)

Author

MENOTTI A, SECCARECCIA F, THE RIFLE RESEARCH GROUP, LANTI M, FARCHI G, CONTI S, DIMA F, SCANGA M, MARENCO G, FALCHERO M, FERRARIO M, CESANA GC, TENCONI MT, LADDOMADA MS, DOBRILLA G, DE PETRIS G, ANGELINI GP, OCKOLICSANYI L, TOSO S, AMBROSIO GB, BITTOLO BON G, ALESSANDRINI P, FERUGLIO GA, VANUZZO D, CARULLI N, SALVIOLI GF, GADDI A, D'ADDATO S, ALVISI V, BUZZELLI GP, GIACCHI M, LAURENZI M, SPAGNOLO A, RICCI G, ANTONINI R, ANGELICO F, LALLONI L, ATTILI AF, URBINATI GC, GIAMPAOLI S, MANCINI M, PANICO S, FARINARO E, ALBANO O, MISCIAGNA G, MUNTONI S, STABILINI L, AVELLONE G, DI GARBO G. ., DEVOTI, Gabriele, Menotti, A, Seccareccia, F, THE RIFLE RESEARCH, Group, Lanti, M, Farchi, G, Conti, S, Dima, F, Scanga, M, Marenco, G, Falchero, M, Ferrario, M, Cesana, Gc, Tenconi, Mt, Laddomada, M, Devoti, Gabriele, Dobrilla, G, DE PETRIS, G, Angelini, Gp, Ockolicsanyi, L, Toso, S, Ambrosio, Gb, BITTOLO BON, G, Alessandrini, P, Feruglio, Ga, Vanuzzo, D, Carulli, N, Salvioli, Gf, Gaddi, A, D'Addato, S, Alvisi, V, Buzzelli, Gp, Giacchi, M, Laurenzi, M, Spagnolo, A, Ricci, G, Antonini, R, Angelico, F, Lalloni, L, Attili, Af, Urbinati, Gc, Giampaoli, S, Mancini, M, Panico, S, Farinaro, E, Albano, O, Misciagna, G, Muntoni, S, Stabilini, L, Avellone, G, and DI GARBO, G. .

Published
1997

23. Syndrome X: prevalence in a large population-based study

Author

LIU J, TREVISAN M, MENOTTI A, THE RIFLE RESEARCH GROUP, LANTI M, FARCHI G, CONTI S, SECCARECCIA F, DIMA F, SCANGA M, MARENCO G, FALCHERO M, FERRARIO M, CESANA GC, TENCONI MT, LADDOMADA MS, DOBRILLA G, DE PETRIS G, ANGELINI GP, OCKOLICSANYI L, TOSO S, AMBROSIO GB, BITTOLO BON G, ALESSANDRINI P, FERUGLIO GA, VANUZZO D, CARULLI N, SALVIOLI GF, GADDI A, D'ADDARO S, ALVISI V, BUZZELLI GP, GIACCHI M, LAURENZI M, SPAGNOLO A, RICCI G, ANTONINI R, ANGELICO F, LALLONI L, ATTILI AF, URBINATI GC, GIAMPAOLI S, MANCINI M, PANICO S, FARINARO E, ALBANO O, MISCIAGNA G, MUNTONI S, STABILINI L, AVELLONE G, DI GARBO G. ., DEVOTI, Gabriele, Liu, J, Trevisan, M, Menotti, A, THE RIFLE RESEARCH, Group, Lanti, M, Farchi, G, Conti, S, Seccareccia, F, Dima, F, Scanga, M, Marenco, G, Falchero, M, Ferrario, M, Cesana, Gc, Tenconi, Mt, Laddomada, M, Devoti, Gabriele, Dobrilla, G, DE PETRIS, G, Angelini, Gp, Ockolicsanyi, L, Toso, S, Ambrosio, Gb, BITTOLO BON, G, Alessandrini, P, Feruglio, Ga, Vanuzzo, D, Carulli, N, Salvioli, Gf, Gaddi, A, D'Addaro, S, Alvisi, V, Buzzelli, Gp, Giacchi, M, Laurenzi, M, Spagnolo, A, Ricci, G, Antonini, R, Angelico, F, Lalloni, L, Attili, Af, Urbinati, Gc, Giampaoli, S, Mancini, M, Panico, S, Farinaro, E, Albano, O, Misciagna, G, Muntoni, S, Stabilini, L, Avellone, G, and DI GARBO, G. .

Published
1997

24. Influence of different strategies of volume replacement on the activity of matrix metalloproteinases: an in vitro and in vivo study

Author

Volta, Carlo Alberto, Alvisi, V, Campi, Matilde, Marangoni, E, Alvisi, Raffaele, Castellazzi, Massimiliano, Fainardi, Enrico, Manfrinato, Maria Cristina, Dallocchio, Franco Pasquale Filippo, and Bellini, Tiziana

Subjects
Adult, Male, Ringer's Lactate, Tissue Inhibitor of Metalloproteinase-1, Plasma Substitutes, Matrix Metalloproteinase Inhibitors, Middle Aged, NO, Hydroxyethyl Starch Derivatives, Oxygen, Matrix Metalloproteinase 9, Polygeline, Humans, Female, Isotonic Solutions, Aged
Abstract

Excessive production of matrix metalloproteinase 9 (MMP-9) is linked to tissue damage and anastomotic leakage after large bowel surgery. Hence, the aim of this study was to verify whether different strategies of fluids administration can reduce MMP-9 expression.In the in vitro experiment, the authors tested the hypothesis of a direct inhibition of MMP-9 by the fluids used perioperatively, i.e., lactated Ringer's solution, 3.4% poligeline, and hydroxyethyl starch 130/0.4. In the in vivo experiment, 36 patients undergoing surgery for colon cancer were randomly assigned to three groups to receive lactated Ringer's solution, poligeline, or hydroxyethyl starch. MMP-9 and tissue inhibitor of metalloproteinases were measured from venous blood samples; the MMP-9/tissue inhibitor of metalloproteinases ratio was calculated as an index of equilibrium between the action of MMP-9 and its inhibition.In the in vitro experiment, the presence of hydroxyethyl starch 130/0.4 in the MMP-9 assay system showed a strong inhibition of the enzymatic activity compared with lactated Ringer's solution. In the in vivo experiment, MMP-9 and tissue inhibitor of metalloproteinases plasma levels did not differ among the three groups at baseline, whereas those levels increased significantly at the end of surgery. At that time, the MMP-9 plasma levels and the MMP-9/tissue inhibitor of metalloproteinases ratio were significantly higher in the lactated Ringer's solution and poligeline groups than in the hydroxyethyl starch group. These results were confirmed 72 h after surgery.This study demonstrates that hydroxyethyl starch 130/04 decreases the circulating levels of MMP-9 in patients undergoing abdominal surgery.

Published
2007

27. Mean levels and distributions of some cardiovascular risk factors in Italy in the 1970's and the 1980's. The Italian RIFLE Pooling Project. Risk Factors and Life Expectancy

Author

MENOTTI A, SECCARECCIA F, LANTI M, THE RIFLE PROJECT RESEARCH GROUP, FARCHI G, CONTI S, DIMA F, SCANGA M, MARENCO G, FALCHERO M, IDEO G, PODDA M, FERRARIO M, CESANA GC, TENCONI MT, MUSSI A, DOBRILLA G, DE PETRIS G, ANGELINI GP, OCKOLICSANYI L, TOSO S, AMBROSIO GB, BITTOLO BON G, ALESSANDRINI P, FERUGLIO GA, VANUZZO D, CARULLI N, SALVIOLI GF, GADDI A, D'ADDARO S, ALVISI V, BUZZELLI GP, GIACCHI M, LAURENZI M, SPAGNOLO A, RICCI G, ANTONINI R, ANGELICO F, LALLONI L, ATTILI AF, URBINATI GC, GIAMPAOLI S, MANCINI M, PANICO S, FARINARO E, ALBANO O, MISCIAGNA G, MUNTONI S, STABILINI L, AVELLONE G, DI GARBO G. ., DEVOTI, Gabriele, Menotti, A, Seccareccia, F, Lanti, M, THE RIFLE PROJECT RESEARCH, Group, Farchi, G, Conti, S, Dima, F, Scanga, M, Marenco, G, Falchero, M, Ideo, G, Podda, M, Ferrario, M, Cesana, Gc, Tenconi, Mt, Mussi, A, Devoti, Gabriele, Dobrilla, G, DE PETRIS, G, Angelini, Gp, Ockolicsanyi, L, Toso, S, Ambrosio, Gb, BITTOLO BON, G, Alessandrini, P, Feruglio, Ga, Vanuzzo, D, Carulli, N, Salvioli, Gf, Gaddi, A, D'Addaro, S, Alvisi, V, Buzzelli, Gp, Giacchi, M, Laurenzi, M, Spagnolo, A, Ricci, G, Antonini, R, Angelico, F, Lalloni, L, Attili, Af, Urbinati, Gc, Giampaoli, S, Mancini, M, Panico, S, Farinaro, E, Albano, O, Misciagna, G, Muntoni, S, Stabilini, L, Avellone, G, and DI GARBO, G. .

Published
1995

29. The prediction of coronary heart disease mortality as a function of major risk factors in over 30000 men in the Italian RIFLE Pooling Project. A comparison with the MRFIT primary screenees

Author

MENOTTI A, FARCHI G, SECCARECCIA F, THE RIFLE RESEARCH GROUP, CONTI S, GIAMPAOLI S, LANTI M, MARIOTTI S, SCANGA M, MARENCO G, FALCHERO M, IDEO G, PODDA M, FERRARIO M, CESANA GC, TENCONI MT, LADDOMADA MS, DOBRILLA G, DE PETRIS G, ANGELINI GP, OCKOLICSANYI L, TOSO S, AMBROSIO GB, BITTOLO BON G, ALESSANDRINI P, FERUGLIO GA, VANUZZO D, CARULLI N, SALVIOLI GF, GADDI A, D'ADDARO S, ALVISI V, BUZZELLI GP, GIACCHI M, LAURENZI M, SPAGNOLO A, RICCI G, ANTONINI R, ANGELICO F, LALLONI L, ATTILI AF, URBINATI GC, MANCINI M, PANICO S, FARINARO E, ALBANO O, MISCIAGNA G, MUNTONI S, STABILINI L, AVELLONE G, DI GARBO G. ., DEVOTI, Gabriele, Menotti, A, Farchi, G, Seccareccia, F, THE RIFLE RESEARCH, Group, Conti, S, Giampaoli, S, Lanti, M, Mariotti, S, Scanga, M, Marenco, G, Falchero, M, Ideo, G, Podda, M, Ferrario, M, Cesana, Gc, Tenconi, Mt, Laddomada, M, Devoti, Gabriele, Dobrilla, G, DE PETRIS, G, Angelini, Gp, Ockolicsanyi, L, Toso, S, Ambrosio, Gb, BITTOLO BON, G, Alessandrini, P, Feruglio, Ga, Vanuzzo, D, Carulli, N, Salvioli, Gf, Gaddi, A, D'Addaro, S, Alvisi, V, Buzzelli, Gp, Giacchi, M, Laurenzi, M, Spagnolo, A, Ricci, G, Antonini, R, Angelico, F, Lalloni, L, Attili, Af, Urbinati, Gc, Mancini, M, Panico, S, Farinaro, E, Albano, O, Misciagna, G, Muntoni, S, Stabilini, L, Avellone, G, and DI GARBO, G. .

Published
1994

31. Presentation of the RIFLE Project Risk Factors and Life Expectancy

Author

THE RIFLE RESEARCH GROUP, MENOTTI A, FARCHI G, CONTI S, GIAMPAOLI S, LANTI M, MARIOTTI S, SCANGA M, SECCARECCIA F, SPAGNOLO A, VERDECCHIA A, DI CARLO G, DIMA F, MARENCO G, FALCHERO M, IDEO G, PODDA M, FERRARIO M, CESANA GC, TENCONI MT, LADDOMADA MS, DOBRILLA G, DE PETRIS G, ANGELINI GP, OCKOLICSANYI L, TOSO S, AMBROSIO GB, TASSO S, BITTOLO BON G, ALESSANDRINI P, FERUGLIO GA, VANUZZO D, CARULLI N, SALVIOLI GF, GADDI A, D'ADDATO S, DESCOVICH GC, DORMI A, BARBARA L, ALVISI V, BUZZELLI GP, GIACCHI M, LAURENZI M, RICCI G, ANTONINI R, ANGELICO F, LALLONI L, ATTILI AF, URBINATI GC, MANCINI M, PANICO S, FARINARO E, ALBANO O, MISCIAGNA G, MUNTONI S, STABILINI L, AVELLONE G, DI GARBO G. ., DEVOTI, Gabriele, THE RIFLE RESEARCH, Group, Menotti, A, Farchi, G, Conti, S, Giampaoli, S, Lanti, M, Mariotti, S, Scanga, M, Seccareccia, F, Spagnolo, A, Verdecchia, A, DI CARLO, G, Dima, F, Marenco, G, Falchero, M, Ideo, G, Podda, M, Ferrario, M, Cesana, Gc, Tenconi, Mt, Laddomada, M, Devoti, Gabriele, Dobrilla, G, DE PETRIS, G, Angelini, Gp, Ockolicsanyi, L, Toso, S, Ambrosio, Gb, Tasso, S, BITTOLO BON, G, Alessandrini, P, Feruglio, Ga, Vanuzzo, D, Carulli, N, Salvioli, Gf, Gaddi, A, D'Addato, S, Descovich, Gc, Dormi, A, Barbara, L, Alvisi, V, Buzzelli, Gp, Giacchi, M, Laurenzi, M, Ricci, G, Antonini, R, Angelico, F, Lalloni, L, Attili, Af, Urbinati, Gc, Mancini, M, Panico, S, Farinaro, E, Albano, O, Misciagna, G, Muntoni, S, Stabilini, L, Avellone, G, and DI GARBO, G. .

Published
1993

42. Real-time contrast-enhanced ultrasound--a new simple tool for detection of peritoneal-pleural communications in hepatic hydrothorax

Author

Foschi, Fg, Piscaglia, Fabio, Pompili, Maurizio, Corbelli, C, Marano, G, Righini, R, Alvisi, V, Gasbarrini, Giovanni Battista, Bolondi, L, Bernardi, M, Stefanini, Gf, Pompili, Maurizio (ORCID:0000-0001-6699-7980), Bernardi , M, Foschi, Fg, Piscaglia, Fabio, Pompili, Maurizio, Corbelli, C, Marano, G, Righini, R, Alvisi, V, Gasbarrini, Giovanni Battista, Bolondi, L, Bernardi, M, Stefanini, Gf, Pompili, Maurizio (ORCID:0000-0001-6699-7980), and Bernardi , M

Abstract

PURPOSE: Hepatic hydrothorax is defined as the accumulation of pleural effusion in a cirrhotic patient in the absence of pulmonary or cardiac disease. Peritoneal fluid can pass into the pleural space through diaphragmatic fenestrations. The demonstration of such passage is important to establish the diagnosis of hepatic hydrothorax and can be achieved by intraperitoneal injection of nuclear contrast agents. Our aim was to evaluate the ability of contrast enhanced ultrasound in the detection of peritoneal-pleural communications. MATERIALS AND METHODS: Seven patients with cirrhotic ascites and pleural effusion were studied in order to make a diagnosis of hepatic hydrothorax. SonoVue was injected into the peritoneal cavity (9.8 mL), and the peritoneal and pleural cavities were monitored by ultrasound. All patients were then studied using a nuclear scan. RESULTS: Passage of SonoVue from the peritoneal to the pleural cavities was seen in 5 patients. In 2 patients, no passage of contrast agent was detectable. Nuclear scan was consistent with contrast enhanced ultrasound in all patients. CONCLUSION: This study shows that the presence of peritoneal-pleural communications can be demonstrated by real time contrast enhanced ultrasound, whose results are comparable to those of nuclear scan. Contrast enhanced ultrasound is cheaper and could theoretically be performed wherever ultrasound facilities are available.

Published
2008

47. Risk of pancreatic cancer associated with cholelithiasis, cholecystectomy, or gastrectomy

Author

Gullo, L., Pezzilli, R., Morsellilabate, A. M., Casadei, R., Campione, O., Brambati, M., Lesi, C., Andriulli, A., Acquadro, P., Dambrosi, A., Alvisi, V., Montalto, G., Carroccio, A., Deconca, V., Mornese, A., Mansi, C., Malesci, A., Zerbi, A., Battistini, C., Sperti, C., Pasquali, C., Gaeta, Luigi, and Felder, M.

Subjects
Adult, Male, medicine.medical_specialty, Pancreatic disease, Physiology, medicine.medical_treatment, pancreatic cancer, Gastroenterology, Cholelithiasis, Gastrectomy, Risk Factors, Internal medicine, Pancreatic cancer, medicine, Confidence Intervals, Odds Ratio, Humans, Cholecystectomy, Aged, business.industry, Case-control study, Cancer, Odds ratio, Middle Aged, medicine.disease, gastrectomy, cholecystectomy, cholelithiasis, Confidence interval, Pancreatic Neoplasms, Case-Control Studies, Female, business
Abstract

Current data regarding an association between cholelithiasis, cholecystectomy, or gastrectomy and pancreatic cancer are conflicting. We evaluated the frequency with which these factors were present in 720 patients with newly diagnosed pancreatic cancer and in 720 matched controls. All subjects were interviewed personally and in detail about their clinical history. Cholelithiasis was present in 126 patients with pancreatic cancer (17.5%) and in 95 controls (13.2%), constituting a statistically significant association (odds ratio, 1.39; 95% confidence interval, 1.04–1.86); however, considering only the patients and controls in whom the diagnosis of cholelithiasis was made more than one year before cancer diagnosis or interview, the association was no longer significant (odds ratio, 1.04; 95% confidence interval, 0.75–1.44). Cholecystectomy had been performed in 93 patients with pancreatic cancer (12.9%) and in 71 controls (9.9%). When all subjects were considered, the odds ratio was mildly, although not significantly, increased (odds ratio, 1.35; 95% confidence interval, 0.97–1.87); when only subjects who underwent cholecystectomy one year or more before the cancer diagnosis or interview were considered, the odds ratio fell to unity. Gastrectomy had been performed in 28 patients with pancreatic cancer (3.9%) and in 25 controls (3.5%); analysis revealed no significant association between these two factors (odds ratio, 1.14; 95% confidence interval, 0.64–2.05). In conclusion, our study, one of the largest on this topic, has found no evidence for an association between cholelithiasis, cholecystectomy, or gastrectomy and pancreatic cancer.

Published
1996

50. Sindrome epatopolmonare

Author

Fabbri, Lm, Ricci, Giorgio, Fugagnoli, A, Caramori, Gaetano, Alvisi, V, and Ciaccia, A.

Subjects
Fegato, malattie respiratorie, polmoni
Published
1996

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