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3. Unveiling cancer risk in ANCA-associated vasculitis: result from the Turkish Vasculitis Study Group (TRVaS)

Author

Bilgin, Emre, Demirci Yıldırım, Tuba, Özdemir Ulusoy, Bahar, Öğüt, Tahir Saygın, Karabacak, Murat, Sadioğlu Çağdaş, Öznur, Yıldırım, Reşit, Güven, Deniz Can, Akleylek, Cansu, Ediboğlu, Elif, Kutu, Muhammet Emin, Özgür, Duygu, Kardaş, Rıza Can, Bölek, Ertuğrul Çağrı, Sandal Uzun, Güllü, Özsoy, Zehra, Sarıyıldız, Emine, Ayan, Gizem, Armağan, Berkan, Erden, Abdulsamet, Kılıç, Levent, Erbasan, Funda, Alibaz-Öner, Fatma, Aşıcıoğlu, Ebru, Yazıcı, Ayten, Bilge, Nazife Şule, Küçük, Hamit, Çelik, Selda, Bes, Cemal, Akar, Servet, Yılmaz, Neslihan, Kaşifoglu, Timucin, Cefle, Ayse, Direskeneli, Haner, Yazısız, Veli, Dizdar, Ömer, Omma, Ahmet, Önen, Fatoş, and Karadağ, Ömer

Published
2024
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4. Assessing safety and efficacy of TNFi treatment in late onset ankylosing spondylitis: a TURKBIO registry study

Author

Uslu, Sadettin, Gulle, Semih, Sen, Gercek, Cefle, Ayse, Yilmaz, Sema, Kocaer, Sinem Burcu, Yuce Inel, Tuba, Koca, Suleyman Serdar, Yolbas, Servet, Ozturk, Mehmet Akif, Senel, Soner, Inanc, Nevsun, Dalkilic, Huseyin Ediz, Soysal Gunduz, Ozgul, Tufan, Abdurrahman, Akar, Servet, Birlik, Ahmet Merih, Sari, Ismail, Akkoc, Nurullah, and Onen, Fatos

Published
2024
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5. Frequency and the effects of spondyloarthritis-spectrum disorders on the clinical course and management of Takayasu arteritis: an observational retrospective study

Author

Abacar, Kerem, Kaymaz-Tahra, Sema, Bayındır, Özün, İnce, Burak, Kutu, Muhammet Emin, Yazıcı, Ayten, Ediboğlu, Elif Durak, Demirci-Yıldırım, Tuba, Ademoğlu, Zeliha, Omma, Ahmet, Yaşar-Bilge, Nazife Şule, Kimyon, Gezmiş, Kaşifoğlu, Timuçin, Emmungil, Hakan, Önen, Fatoş, Akar, Servet, Cefle, Ayşe, Alpay-Kanıtez, Nilüfer, Çelik, Selda, İnanç, Murat, Aksu, Kenan, Keser, Gökhan, Direskeneli, Haner, and Alibaz-Öner, Fatma

Published
2024
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10. Correction: Unveiling cancer risk in ANCA-associated vasculitis: result from the Turkish Vasculitis Study Group (TRVaS)

Author

Bilgin, Emre, Yıldırım, Tuba Demirci, Ulusoy, Bahar Özdemir, Öğüt, Tahir Saygın, Karabacak, Murat, Çağdaş, Öznur Sadioğlu, Yıldırım, Reşit, Güven, Deniz Can, Akleylek, Cansu, Ediboğlu, Elif, Kutu, Muhammet Emin, Özgür, Duygu, Kardaş, Rıza Can, Bölek, Ertuğrul Çağrı, Uzun, Güllü Sandal, Özsoy, Zehra, Sarıyıldız, Emine, Ayan, Gizem, Armağan, Berkan, Erden, Abdulsamet, Kılıç, Levent, Erbasan, Funda, Alibaz-Öner, Fatma, Aşıcıoğlu, Ebru, Yazıcı, Ayten, Bilge, Nazife Şule, Küçük, Hamit, Çelik, Selda, Bes, Cemal, Akar, Servet, Yılmaz, Neslihan, Kaşifoglu, Timucin, Cefle, Ayse, Direskeneli, Haner, Yazısız, Veli, Dizdar, Ömer, Omma, Ahmet, Önen, Fatoş, and Karadağ, Ömer

Published
2024
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13. Comparison of methotrexate and azathioprine as the first-line steroid-sparing immunosuppressive agents in patients with Takayasu's arteritis

Author

Kaymaz-Tahra, Sema, Bayindir, Ozun, Ince, Burak, Ozdemir İsik, Ozlem, Kutu, Muhammet Emin, Karakas, Ozlem, Yildirim, Tuba Demirci, Ademoglu, Zeliha, Ediboglu, Elif Durak, Uludogan, Burcu Ceren Ekti, Ilgin, Can, Bilge, Nazife Sule Yasar, Kasifoglu, Timucin, Akar, Servet, Emmungil, Hakan, Onen, Fatos, Omma, Ahmet, Kanitez, Nilufer Alpay, Yazici, Ayten, Cefle, Ayse, Inanc, Murat, Aksu, Kenan, Keser, Gokhan, Direskeneli, Haner, and Alibaz-Oner, Fatma

Published
2024
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17. Mortality in psoriatic arthritis patients, changes over time, and the impact of COVID-19: results from a multicenter Psoriatic Arthritis Registry (PsART-ID)

Author

Erden, Abdulsamet, Ayan, Gizem, Kilic, Levent, Solmaz, Dilek, Bakirci, Sibel, Kimyon, Gezmis, Günal, Esen Kasapoglu, Dogru, Atalay, Bayindir, Ozun, Dalkilic, Ediz, Özisler, Cem, Akar, Servet, Cetin, Gözde Yildirim, Tarhan, Emine Figen, Küçüksahin, Orhan, Omma, Ahmet, Gonullu, Emel, Yildiz, Fatih, Ersozlu, Emine Duygu, Cinar, Muhammed, Tufan, Abdurrahman, Pehlevan, Seval, Esmen, Serpil Ergulu, Yilmaz, Sema, Duruoz, Tuncay, Kasifoglu, Timucin, Yazısız, Veli, Aksu, Kenan, Aydin, Sibel Zehra, and Kalyoncu, Umut

Published
2023
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20. Tuberculin skin test before biologic and targeted therapies: does the same rule apply for all?

Author

İlgen, Ufuk, Karadağ, Ömer, Emmungil, Hakan, Küçükşahin, Orhan, Koca, Süleyman Serdar, Erden, Abdülsamet, Bes, Cemal, Alpay Kanıtez, Nilüfer, Dalkılıç, Ediz, Akar, Servet, Mercan, Rıdvan, Çınar, Muhammet, Kaşifoğlu, Timuçin, Gönüllü, Emel, Kimyon, Gezmiş, Ersözlü, Duygu, Atagündüz, Pamir, Kılıç, Levent, Ertenli, İhsan, Yazısız, Veli, Ateş, Aşkın, Kiraz, Sedat, and Kalyoncu, Umut

Published
2022
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22. Environmental and societal factors associated with COVID-19-related death in people with rheumatic disease: an observational study

Author

Dahou, Brahim, Gómez, Gimena, Roberts, Karen, Baez, Roberto M, Castro Coello, Vanessa V, Haye Salinas, María J, Maldonado, Federico N, Reyes, Alvaro A, Alle, Gelsomina, Tanten, Romina, Maldonado Ficco, Hernán, Nieto, Romina, Gobbi, Carla, Tissera, Yohana, Pisoni, Cecilia, Paula, Alba, Albiero, Juan A, Schmid, Maria M, Cosatti, Micaela, Gamba, Maria J, Leandro, Carlevaris, Cusa, María A, German, Noelia, Bellomio, Veronica, Takashima, Lorena, Pera, Mariana, Cogo, Karina, Gálvez Elkin, Maria S, Medina, María A, Savio, Veronica, Rojas Tessel, Romina, Alamino, Rodolfo P, Werner, Marina L, Ornella, Sofía, Casalla, Luciana, de la Vega, Maria, Severina, María, García, Mercedes, Gonzalez Lucero, Luciana, Romeo, Cecilia, Moyano, Sebastián, Barbich, Tatiana, Bertoli, Ana, Baños, Andrea, Petruzzelli, Sandra, Matellan, Carla, Conti, Silvana, Lazaro, Maria A, Rodriguez Gil, Gustavo F, Risueño, Fabian, Quaglia, Maria I, Scafati, Julia, Cuchiaro, Natalia L, Rebak, Jonathan E, Pineda, Susana I, Calvo, María E, Picco, Eugenia, Yanzi, Josefina G, Maid, Pablo, Guaglianone, Debora, Morbiducci, Julieta S, Porta, Sabrina, Herscovich, Natalia, Velasco Zamora, José L, Kisluk, Boris, Castaños Menescardi, Maria S, Gallo, Rosana, Martire, María V, Maldini, Carla, Goizueta, Cecilia, de la Vega Fernandez, Sabrina S, Aeschlimann, Carolina, Subils, Gisela, Rath, Eva, Piette, Yves, Devinck, Mieke, Maeyaert, Bea, Machado Ribeiro, Francinne, Euzebio Ribeiro, Sandra L, Pinheiro, Marcelo, Ibáñez, Sebastián, Chassin Trubert, Anne-Marie, Dong, Lingli, Cajas, Lui, Barešić, Marko, Anić, Branimir, Ćulo, Melanie-Ivana, Pavelić, Tea A, Stranski, Kristina K, Karanovic, Boris, Vencovsky, Jiri, Píchová, Marta, Filkova, Maria, Hamoud, Hesham, Vassilopoulos, Dimitrios, Guzman Melgar, Gabriela M, So, Ho, Király, Márta, Vojdanian, Mahdi, Balbir Gurman, Alexandra, Abutiban, Fatemah, Zepa, Julija, Bulina, Inita, Bukauskiene, Loreta, Zazueta Montiel, Beatriz E, Castillo Ortiz, Angel A, Zamora Tehozol, Erick, Vega Morales, David, Cervántes Rosete, Diana, Martín Nares, Eduardo, Rodriguez Reyna, Tatiana S, Rull Gabayet, Marina, Alpízar Rodríguez, Deshiré, Irazoque, Fedra, Jimenez, Xochitl, Geurts van Bon, Lenny, Zijlstra, Theo, Hoekstra, Monique, Al Adhoubi, Nasra, Salim, Babur, Giraldo, Enrique, Salinas, Ariel, Ugarte Gil, Manuel, Nowakowski, Jarosław, Conway, Richard, Flood, Rachael, McCarthy, Geraldine, Felea, Ioana, Filipescu, Ileana, Rednic, Simona, Groseanu, Laura, Tamas, Maria M, Mlynarikova, Vanda, Skamlova, Martina, Zlnay, Martin, Mičeková, Dagmar, Capova, Lubica, Macejova, Zelmira, Šteňová, Emőke, Raffayova, Helena, Belakova, Gabriela, Strakova, Eva, Senčarová, Marieta, Žlnayová, Soňa, Sabová, Anna, Spisakova, Daniela, Oetterová, Mária, Lukacova, Olga, Bakosova, Martina, Hocevar, Alojzija, de la Torre Rubio, Natalia, Alegre Sancho, Juan J, Corteguera Coro, Montserrat, Cobeta Garcia, Juan C, Torres Martin, Maria C, Campos, Jose, Gomez Puerta, Jose A, Yardimci, Gozd K, Akar, Servet, Icacan, Ozan C, ÇELİK, Selda, Vasylets, Viktoriia, Yeoh, Su-Ann, Vandevelde, Claire, Dunt, Sasha, Leeder, Jane, Macphie, Elizabeth, Salerno, Rosaria, Graver, Christine, Williams, Katie, O'Reilly, Sheila, Devine, Kirsty, Tyler, Jennifer, Warner, Elizabeth, Pilcher, James, Patel, Samir, Nikiphorou, Elena, Chadwick, Laura, Jones, Caroline M, Harrison, Beverley, Thornton, Lucy, O'Kane, Diana, Fusi, Lucia, Low, Audrey, Horton, Sarah, Jatwani, Shraddha, Baig, Sara, Bajwa, Hammad, Berglund, Vernon, Dahle, Angela, Dorman, Walter, Hargrove, Jody, Hilton, Maren, Lebedoff, Nicholas, Leonard, Susan, Morgan, Jennifer, Pfeifer, Emily, Skemp, Archibald, Wilson, Jeffrey, Wolff, Anne, Cepeda, Eduardo, Todd, Derrick, Hare, Denise, Calabrese, Cassandra, Adams, Christopher, Khosroshahi, Arezou, Kilian, Adam, White, Douglas, Winter, Melanie, Fields, Theodore, Siegel, Caroline, Daver, Nicole, Harvey, Melissa, Kramer, Neil, Lamore, Concetta, Hogarty, Suneya, Yeter, Karen, Siddique, Faizah, Ban, Byung, Tanner, Tamar, Ruderman, Eric, Davis, William, Quinet, Robert, Scopelitis, Evangeline, Toribio, Karen, Webb Detiege, Tameka, Zakem, Jerald, Abbass, Khurram, Kepecs, Gilbert, Miranda, Lilliam, Guma, Michael, Haikal, Ammar, Mody, Sushama, Mueller, Daric, Jayatilleke, Arundathi, Zell, JoAnn, Bays, Alison, Dao, Kathryn, Ezzati, Fatemeh, Parks, Deborah, Karp, David, Quiceno, Guillermo, Izadi, Zara, Gianfrancesco, Milena A, Schmajuk, Gabriela, Jacobsohn, Lindsay, Katz, Patricia, Rush, Stephanie, Ja, Clairissa, Taylor, Tiffany, Shidara, Kie, Danila, Maria I, Wysham, Katherine D, Strangfeld, Anja, Mateus, Elsa F, Hyrich, Kimme L, Gossec, Laure, Carmona, Loreto, Lawson-Tovey, Saskia, Kearsley-Fleet, Lianne, Schaefer, Martin, Al-Emadi, Samar, Sparks, Jeffrey A, Hsu, Tiffany Y-T, Patel, Naomi J, Wise, Leanna, Gilbert, Emily, Duarte-García, Alí, Valenzuela-Almada, Maria O, Ugarte-Gil, Manuel F, Ljung, Lotta, Scirè, Carlo A, Carrara, Greta, Hachulla, Eric, Richez, Christophe, Cacoub, Patrice, Thomas, Thierry, Santos, Maria J, Bernardes, Miguel, Hasseli, Rebecca, Regierer, Anne, Schulze-Koops, Hendrik, Müller-Ladner, Ulf, Pons-Estel, Guillermo, Nieto, Romina E, Pisoni, Cecilia N, Tissera, Yohana S, Xavier, Ricardo, Lopes Marques, Claudia D, Pileggi, Gecilmara C S, Robinson, Philip C, Machado, Pedro M, Sirotich, Emily, Liew, Jean W, Hausmann, Jonathan S, Sufka, Paul, Grainger, Rebecca, Bhana, Suleman, Gore-Massy, Monique, Wallace, Zachary S, and Yazdany, Jinoos

Published
2022
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23. A national, multicenter, secondary data use study evaluating efficacy and retention of first-line biologic treatment with tocilizumab in patients with rheumatoid arthritis in real-life setting: results from TURKBIO registry

Author

Yazici, Ayten, Özdemir Işık, Özlem, Dalkılıç, Ediz, Koca, Süleyman Serdar, Pehlivan, Yavuz, Şenel, Soner, Inanc, Nevsun, Akar, Servet, Yılmaz, Sema, Soysal Gündüz, Özgül, Cefle, Ayse, Karakaş, Ömer Fatih, and Onen, Fatos

Published
2022
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24. Comparison of Serum Nesfatin-1 and Visfatin Levels Between Patients with Rheumatoid Arthritis and Healthy Controls.

Author

Gücenmez, Sercan, Özmen, Mustafa, Solmaz, Dilek, Gerçik, Önay, Kalkan, Ahmet Toygar, Kozacı, Leyla Didem, and Akar, Servet

Subjects
RHEUMATOID arthritis treatment, NEUROPEPTIDES, BODY mass index, ENZYME-linked immunosorbent assay, ERYTHROCYTES
Abstract

Copyright of Osmangazi Journal of Medicine / Osmangazi Tip Dergisi is the property of Eskisehir Osmangazi University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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25. Secukinumab May Be an Effective Treatment Option for Axial Spondyloarthritis and Psoriatic Arthritis Patients with a History of Malignancy: Multicenter Real-Life Experience from Turkey.

Author

Ocak, Tuğba, Yağız, Burcu, Ocak, Birol, Yoğurtçu, Özge, Başıbüyük, Fatma, Tezcan, Dilek, Ermurat, Selime, İnanç, Elif, Yamancan, Gülşah, Albayrak, Fatih, Sağır, Rabia Pişkin, Bayındır Akbaş, Ayşe Nur, Cüre, Osman, Coşkun, Belkıs Nihan, Yolbaş, Servet, Karasu, Uğur, Kısacık, Bünyamin, Koca, Süleyman Serdar, Sarı, İsmail, and Akar, Servet

Subjects
INTERLEUKIN-17, PSORIATIC arthritis, DISEASE relapse, SPONDYLOARTHROPATHIES, TRANSITIONAL cell carcinoma
Abstract

Background: Secukinumab is a monoclonal antibody against interleukin 17 approved for patients with axial spondyloarthritis (axSpA), psoriatic arthritis (PsA), and psoriasis. Treating axSpA and PsA patients with a history of malignancy is a challenge. While initial results on the applicability of secukinumab in this patient group are positive, the number of studies on this topic remains limited. This study aimed to investigate the drug's survival time and the efficacy and safety of secukinumab treatment in this specific patient group. Methods: This retrospective study included 30 patients with a history of malignancy who were followed up in rheumatology outpatient clinics in 12 centers throughout Turkey and treated with secukinumab between May 2018 and March 2024 with a diagnosis of axSpA and PsA. Results: The mean follow-up time was 29.8 ± 19.3 months. The drug retention rate was 89.7% after 12 months and 80.6% after 24 months. The most common tumor in our study was papillary thyroid carcinoma (n = 5, 16.7%). During follow-up, local tumor recurrence was observed in a patient with urothelial carcinoma of the bladder. Conclusions: In the largest cohort reported to date, treatment with secukinumab in axSpA and PsA patients with a history of malignancy was not shown to cause oncologic recurrence except for one local tumor recurrence. Drug retention rates were also high, and disease activation and function improved compared to baseline. Therefore, secukinumab could be a safe and effective option for this patient group. [ABSTRACT FROM AUTHOR]

Published
2024
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26. Major Determinants of Well‐Being in Patients With Axial Spondyloarthritis: 2 Year Follow‐Up.

Author

Ediboglu, Elif Durak, Erpek, Esra, Bayraktar, Deniz, Özmen, Mustafa, Solmaz, Dilek, and Akar, Servet

Subjects
HEALTH status indicators, ANKYLOSIS, QUESTIONNAIRES, SEX distribution, HEALTH surveys, MULTIVARIATE analysis, SEVERITY of illness index, QUALITY of life, SPONDYLOARTHROPATHIES, SOCIODEMOGRAPHIC factors, WELL-being
Abstract

Objectives: Bath Ankylosing Spondylitis Patient Global Score (BAS‐G) is a uni‐dimensional scale that enables patients to evaluate the effects of their illness on their health. The aim of this study was to determine the impact of disease related outcomes on the BAS‐G scores in patients with axSpA. Methods: A total of 309 patients (56.6% of whom were male, mean age 44 ± 11) were included in the study. Socio‐demographic characteristics (age, sex and education level) and clinical characteristics such as disease activity (BASDAI and CRP), spinal mobility (BASMI), functional status (BASFI), radiographic structural damage (mSASS, mNY, and BASRI‐hip), and health related quality of life (SF‐36 and ASQoL) of the patients were recorded at baseline. In addition, BASDAI total and each item score, BASFI, BAS‐G, and CRP levels were collected at 6, 12, and 24 months. Results: Female patients had significantly higher BAS‐G scores (p = 0.037). Baseline BASDAI total score (p < 0.001) and all BASDAI item scores (p < 0.001 for each item), BASFI total score (p < 0.001), ASQoL total score (p < 0.001), and SF‐36 PCS sum‐score (p < 0.001) were moderately/highly correlated with BAS‐G. Multivariate analysis revealed that back pain (BASDAI Q2) (p < 0.001) and the severity of morning stiffness (BASDAI Q5) (p < 0.001) were the main determinants of BAS‐G in patients with axSpA. In 2‐year follow‐up, BASDAI Q1, BASDAI Q5, and BASFI scores were independent determinants of BAS‐G in patients with axSpA. Conclusion: According to the results of the present study, patients with axSpA mainly rely on morning stiffness and back pain to determine their global health status. Moreover, fatigue, severity of morning stiffness and function are the determinants of BAS‐G during follow‐up. [ABSTRACT FROM AUTHOR]

Published
2024
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27. Validity and reliability of the Turkish version of Exercise Benefits/ Barriers Scale: Perceived exercise benefits and barriers of patients with different axial spondyloarthritis subtypes.

Author

Sarac, Devrim Can, Ediboglu, Elif Durak, Kaya, Derya Ozer, Duran, Gozde, Akatay, Emre Alp, Gucenmez, Sercan, Akar, Servet, and Bayraktar, Deniz

Subjects
PHOBIAS, EXERCISE, CRONBACH'S alpha, HEALTH status indicators, QUESTIONNAIRES, RESEARCH methodology evaluation, ANKYLOSIS, RESEARCH methodology, STATISTICAL reliability, INTRACLASS correlation, QUALITY of life, SPONDYLOARTHROPATHIES, BODY movement, PATIENTS' attitudes
Abstract

Objectives: The aim of this study was to translate the Exercise Benefits/Barriers Scale (EBBS) into Turkish and investigate the perceptions of Turkish-speaking patients with different axial spondyloarthritis (axSpA) subtypes regarding exercise benefits and barriers. Patients and methods: This validation study was conducted between June 2018 and December 2021. Patients with axSpA were consecutively assessed regarding physical (age, sex and body mass index) and disease-related characteristics (disease activity, spinal mobility, functional status, quality of life, health status, emotional status, and kinesiophobia). Eligible participants were asked to complete the EBSS and other outcome measurements during their initial visits. EBBS was readministered 7 to 14 days later. Results: One hundred forty-eight patients (89 males, 59 females; mean age: 44.3±11.8 years; range, 19 to 65 years) were included in the study. Of the patients, 108 had radiographic axSpA, and 40 had nonradiographic axSpA. EBBS-Barriers and EBBS-Benefits subscales demonstrated adequate internal consistency (Cronbach’s alphas of 0.82 and 0.95, respectively) and test-retest reliability (intraclass correlation coefficients of 0.837 and 0.807, respectively). No significant differences were observed between axSpA subtypes regarding EBBS-Barriers (p=0.12) and EBBS-Benefits (p=0.10) subscales. Significant relationships were detected between kinesiophobia and EBBS-Barriers scores (r=–0.424, p<0.01), as well as EBBS-Benefits scores (r=–0.344, p<0.01) for all patients. EBBS-Benefits scores were correlated to health status (r=–0.412, p=0.08) and quality of life (r=–0.394, p=0.01) in patients with nonradiographic axSpA. Conclusion: According to our results, the Turkish EBBS is a valid and reliable tool for patients with axSpA. Perceptions of the patients with axSpA regarding exercise barriers and benefits do not differ according to the disease subtype. It appears that kinesiophobia may be an important parameter regarding exercise perception in axSpA. [ABSTRACT FROM AUTHOR]

Published
2024
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28. Outcomes of COVID-19 in patients with primary systemic vasculitis or polymyalgia rheumatica from the COVID-19 Global Rheumatology Alliance physician registry: a retrospective cohort study

Author

Dahou, Brahim, Rath, Eva, Piette, Yves, Devinck, Mieke, Maeyaert, Bea, Machado Ribeiro, Francinne, Euzebio Ribeiro, Sandra Lucia, Pinheiro, Marcelo, Quintana, Rosana, Gómez, Gimena, Roberts, Karen, Baez, Roberto Miguel, Castro Coello, Vanessa, Haye Salinas, María J., Maldonado, Federico Nicolas, Reyes Torres, Alvaro Andres, Alle, Gelsomina, Tanten, Romina, Maldonado Ficco, Hernán, Nieto, Romina, Gobbi, Carla, Tissera, Yohana, Pisoni, Cecilia, Paula, Alba, Albiero, Juan Alejandro, Schmid, Maria Marcela, Cosatti, Micaela, Gamba, Maria Julieta, Leandro, Carlevaris, Cusa, María Alejandra, German, Noelia, Bellomio, Veronica, Takashima, Lorena, Pera, Mariana, Cogo, Karina, Gálvez Elkin, Maria Soledad, Medina, María Alejandra, Savio, Veronica, Rojas Tessel, Ivana Romina, Perez Alamino, Rodolfo, Werner, Marina Laura, Ornella, Sofía, Casalla, Luciana, de la Vega, Maria, Severina, María, García, Mercedes, Gonzalez Lucero, Luciana, Romeo, Cecilia, Moyano, Sebastián, Barbich, Tatiana, Bertoli, Ana, Baños, Andrea, Petruzzelli, Sandra, Matellan, Carla, Conti, Silvana, Lazaro, Ma. Alicia, Rodriguez Gil, Gustavo Fabián, Risueño, Fabian, Quaglia, Maria Isabel, Scafati, Julia, Cuchiaro, Natalia Lili, Rebak, Jonathan Eliseo, Pineda, Susana Isabel, Calvo, María Elena, Picco, Eugenia, Gallino Yanzi, Josefina, Maid, Pablo, Guaglianone, Debora, Morbiducci, Julieta Silvana, Porta, Sabrina, Herscovich, Natalia, Velasco Zamora, José Luis, Kisluk, Boris, Castaños Menescardi, Maria Sol, Gallo, Rosana, Martire, María Victoria, Maldini, Carla, Goizueta, Cecilia, de la Vega Fernandez, Sabrina Solange, Aeschlimann, Carolina, Subils, Gisela, Ibáñez, Sebastián, Chassin-Trubert, Anne-Marie, Dong, Lingli, Cajas, Lui, Barešic, Marko, Anic, Branimir, Culo, Melanie-Ivana, Pavelic, Tea Ahel, Kovacevic Stranski, Kristina, Karanovic, Boris, Vencovsky, Jiri, Píchová, Marta, Filkova, Maria, Hamoud, Hesham, Vassilopoulos, Dimitrios, Guzman Melgar, Gabriela Maria, So, Ho, Király, Márta, Vojdanian, Mahdi, Balbir-Gurman, Alexandra, Abutiban, Fatemah, Zepa, Julija, Bulina, Inita, Bukauskiene, Loreta, Zaueta, Beatriz, Castillo Ortiz, Angel Alejandro, Zamora Tehozol, Erick, Vega, David, Cervántes Rosete, Diana, Martín Nares, Eduardo, Rodriguez-Reyna, Tatiana Sofia, Rull Gabayet, Marina, Alpízar-Rodríguez, Deshiré, Irazoque, Fedra, Jimenez, Xochitl, Geurts-van Bon, Lenny, Zijlstra, Theo, Hoekstra, Monique, Al-Adhoubi, Nasra, Salim, Babur, Giraldo, Enrique, Salinas, Ariel, Ugarte-Gil, Manuel, Nowakowski, Jaroslaw, Al-Emadi, Samar, Conway, Richard, Flood, Rachael, McCarthy, Geraldine, Felea, Ioana, Filipescu, Ileana, Rednic, Simona, Groseanu, Laura, Tamas, Maria Magdelena, Mlynarikova, Vanda, Skamlova, Martina, Zlnay, Martin, Miceková, Dagmar, Capova, Lubica, Macejova, Zelmira, Štenová, Emoke, Raffayova, Helena, Belakova, Gabriela, Strakova, Eva, Sencarová, Marieta, Žlnayová, Sona, Anna Sabová, Anna, Spisakova, Daniela, Oetterová, Mária, Lukacova, Olga, Bakosova, Martina, Hocevar, Alojzija, de la Torre-Rubio, Natalia, Alegre Sancho, Juan José, Corteguera Coro, Montserrat, Cobeta Garcia, Juan Carlos, Torres Martin, Maria Carmen, Campos, Jose, Gomez Puerta, Jose A, Yardimci, Gozd Kubra, Akar, Servet, Icacan, Ozan Cemal, Çelik, Selda, Vasylets, Viktoriia, Yeoh, Su-Ann, Vandevelde, Claire, Dunt, Sasha, Leeder, Jane, Macphie, Elizabeth, Salerno, Rosaria, Graver, Christine, Williams, Katie, O'Reilly, Sheila, Devine, Kirsty, Tyler, Jennifer, Warner, Elizabeth, Pilcher, James, Patel, Samir, Nikiphorou, Elena, Chadwick, Laura, Jones, Caroline Mulvaney, Harrison, Beverley, Thornton, Lucy, O'Kane, Diana, Fusi, Lucia, Low, Audrey, Horton, Sarah, Jatwani, Shraddha, Baig, Sara, Bajwa, Hammad, Berglund, Vernon, Dahle, Angela, Dorman, Walter, Hargrove, Jody, Hilton, Maren, Lebedoff, Nicholas, Leonard, Susan, Morgan, Jennifer, Pfeifer, Emily, Skemp, Archibald, Wilson, Jeffrey, Wolff, Anne, Cepeda, Eduardo, D'Silva, Kristin, Hsu, Tiffany, Patel, Naomi, Sparks, Jeffrey, Todd, Derrick, Wallace, Zachary, Hare, Denise, Calabrese, Cassandra, Adams, Christopher, Khosroshahi, Arezou, Kilian, Adam, White, Douglas, Winter, Melanie, Fields, Theodore, Siegel, Caroline, Daver, Nicole, Harvey, Melissa, Kramer, Neil, Lamore, Concetta, Hogarty, Suneya, Yeter, Karen, Wise, Leanna, Siddique, Faizah, Ban, Byung, Tanner, Tamar, Ruderman, Eric, Davis, William, Quinet, Robert, Scopelitis, Evangeline, Toribio Toribio, Karen, Webb-Detiege, Tameka, Zakem, Jerald, Abbass, Khurram, Kepecs, Gilbert, Miranda, Lilliam, Guma, Michael, Haikal, Ammar, Mody, Sushama, Mueller, Daric, Jayatilleke, Arundathi, Zell, JoAnn, Bays, Alison, Dao, Kathryn, Fatemeh, Ezzati, Parks, Deborah, Karp, David, Quiceno, Guillermo, Sattui, Sebastian E, Putman, Michael S, Seet, Andrea M, Gianfrancesco, Milena A, Beins, Kaley, Hill, Catherine, Liew, David, Mackie, Sarah L, Mehta, Puja, Neill, Lorna, Gomez, Gimena, Salinas, Maria Isabel Haye, Mariz, Henrique Ataide, de Sousa Studart, Samia Araujo, Araujo, Nafice Costa, Knight, Ann, Rozza, Davide, Quartuccio, Luca, Samson, Maxime, Bally, Stéphane, Maria, Alexandre TJ, Chazerain, Pascal, Hasseli, Rebecca, Müller-Ladner, Ulf, Hoyer, Bimba F, Voll, Reinhard, Torres, Rita Pinheiro, Luis, Mariana, Ribeirio, Sandra Lucia Euzebio, Sparks, Jeffrey A, Hsu, Tiffany Y-T, D’Silva, Kristin M, Patel, Naomi J, Gilbert, Emily, Almada, Maria Valenzuela, Duarte-García, Alí, Jacobsohn, Lindsay, Izadi, Zara, Strangfeld, Anja, Mateus, Elsa F, Hyrich, Kimme L, Gossec, Laure, Carmona, Loreto, Lawson-Tovey, Saskia, Kearsley-Fleet, Lianne, Schaefer, Martin, Sirotich, Emily, Hausmann, Jonathan S, Sufka, Paul, Bhana, Suleman, Liew, Jean W, Grainger, Rebecca, Machado, Pedro M, Wallace, Zachary S, Yazdany, Jinoos, and Robinson, Philip C

Published
2021
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29. Biological treatment in elderly and young patients with ankylosing spondylitis: TURKBIO real-life data results

Author

Uslu, Sadettin, primary, Gülle, Semih, additional, Urak, Özkan, additional, Şen, Gerçek, additional, Dalkılıç, Ediz, additional, Şenel, Soner, additional, Akar, Servet, additional, İnanç, Nevsun, additional, Cefle, Ayşe, additional, Köken Avşar, Aydan, additional, Yolbaş, Servet, additional, Yılmaz, Sema, additional, Soysal Gündüz, Özgül, additional, Sarı, İsmail, additional, Birlik, Merih, additional, Akkoç, Nurullah, additional, and Önen, Fatoş, additional

Published
2024
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32. In the era of disease-modifying antirheumatic drugs, how close are we to treating rheumatoid arthritis without the use of glucocorticoids?

Author

Yagiz, Burcu, Coskun, Belkis Nihan, Pehlivan, Yavuz, Dalkilic, Ediz, Kiraz, Sedat, Yazisiz, Veli, Kucuksahin, Orhan, Erden, Abdulsamet, Kanitez, Nilufer Alpay, Kimyon, Gezmiş, Emmungil, Hakan, Bilge, Sule Yasar, Kasifoglu, Timucin, Bes, Cemal, Bolek, Ertugrul Cagri, Bilgin, Emre, Karatas, Ahmet, Kelesoglu, Bahar, Ersozlu, Duygu, Gonullu, Emel Orge, Mercan, Ridvan, Yilmaz, Sedat, Karadag, Omer, Akar, Servet, Ertenli, Ihsan, and Kalyoncu, Umut

Published
2021
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35. Unveiling Cancer Risk in ANCA-Associated Vasculitis: Result from the Turkish Vasculitis Study Group (TRVaS)

Author

Bilgin, Emre, primary, Yıldırım, Tuba Demirci, additional, Ulusoy, Bahar Özdemir, additional, Öğüt, Tahir Saygın, additional, Karabacak, Murat, additional, Çağdaş, Öznur Sadioğlu, additional, Yıldırım, Reşit, additional, Güven, Deniz Can, additional, Akleylek, Cansu, additional, Ediboğlu, Elif, additional, Kutu, Muhammet Emin, additional, Özgür, Duygu, additional, Kardaş, Riza Can, additional, Bölek, Ertuğrul Çağrı, additional, Uzun, Gül Sandal, additional, Özsoy, Zehra, additional, Sarıyıldız, Emine, additional, Ayan, Gizem, additional, Armağan, Berkan, additional, Erden, Abdussamet, additional, Kılıç, Levent, additional, Erbasan, Funda, additional, Alibaz-Öner, Fatma, additional, Aşıcıoğlu, Ebru, additional, Yazici, Ayten, additional, Bilge, Nazife Şule, additional, Küçük, Hamit, additional, Çelik, Selda, additional, Bes, Cemal, additional, Akar, Servet, additional, Yılmaz, Neslihan, additional, Kaşifoğlu, Timuçin, additional, Cefle, Ayşe, additional, Direskeneli, Haner, additional, Yazısız, Veli, additional, Dizdar, Ömer, additional, Omma, Ahmet, additional, Önen, Fatoş, additional, and Karadağ, Ömer, additional

Published
2024
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38. Radiographic Progression in Sacroiliac Joints in Patients With Axial Spondyloarthritis: Results From a Five‐Year International Observational Study

Author

Poddubnyy, Denis, primary, Sieper, Joachim, additional, Akar, Servet, additional, Muñoz‐Fernández, Santiago, additional, Haibel, Hildrun, additional, Diekhoff, Torsten, additional, Protopopov, Mikhail, additional, Altmaier, Elisabeth, additional, Ganz, Fabiana, additional, and Inman, Robert D., additional

Published
2023
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41. Does obesity affect treatment response to secukinumab and survival in ankylosing spondylitis? Real-life data from the TURKBIO Registry.

Author

Karaka, Ali, Gulle, Semih, Can, Gerçek, Dalkilic, Ediz, Akar, Servet, Koca, Suleyman Serdar, Pehlivan, Yavuz, Senel, Soner, Tufan, Abdurrahman, Ozturk, Mehmet Akif, Yilmaz, Sema, Yazici, Ayten, Cefle, Ayse, Inel, Tuba Yüce, Erez, Yesim, Sari, Ismail, Birlik, Merih, Direskeneli, Haner, Akkoc, Nurullah, and Onen, Fatos

Subjects
ANKYLOSING spondylitis, OBESITY, BODY mass index, BIOLOGICAL databases, SPONDYLOARTHROPATHIES
Abstract

Objectives: The aim of this study was to evaluate the impact of obesity on the treatment response to secukinumab and drug survival rate in patients with ankylosing spondylitis (AS). Methods: We performed an observational cohort study that included AS patients based on the biological drug database in Turkey (TURKBIO) Registry between 2018 and 2021. The patients were divided into three groups: normal [body mass index (BMI) < 25 kg/m2], overweight (BMI: 25–30 kg/m2), and obese (BMI ≥ 30 kg/m2). Disease activity was evaluated at baseline, 3, 6, and 12 months. Drug retention rates at 12 months were also investigated. Results: There were 166 AS patients using secukinumab (56.6% male, mean age: 44.9 ± 11.6 years). The median follow-up time was 17.2 (3–33.2) months. Forty-eight (28.9%) patients were obese. The mean age was higher in the obese group than in others (P = .003). There was no statistically significant difference in Bath Ankylosing Spondylitis Disease Activity Index 50, Assessment of SpondyloArthritis international Society 20 (ASAS20), ASAS40, Ankylosing Spondylitis Disease Activity Score (ASDAS) low disease activity, and ASDAS clinically important improvement responses between the three groups at 3, 6, and 12 months, although they were numerically lower in obese patients. Drug retention rates at 12 months were similar in all groups (P > .05). Conclusions: This study suggested that obesity did not affect secukinumab treatment response and drug retention in AS patients. [ABSTRACT FROM AUTHOR]

Published
2024
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42. Factors associated with acute anterior uveitis history in patients with axial spondyloarthritis: Results of a longitudinal study.

Author

Cinakli, Haluk, Ediboglu, Elif Durak, Solmaz, Dilek, and Akar, Servet

Subjects
IRIDOCYCLITIS, SPONDYLOARTHROPATHIES, GENERALIZED estimating equations, TUMOR necrosis factors, LONGITUDINAL method, PANEL analysis
Abstract

Backgrounds: Acute anterior uveitis (AAU) is the most common extra‐musculoskeletal manifestation in axial spondyloarthritis (axSpA). Objectives: The aim of the study is to evaluate the factors associated with AAU attacks in patients with axSpA during a 36‐month follow‐up period. Methods: In total, 469 patients with axSpA were included in this observational study. Demographic data, clinical characteristics, disease activity measurements, and treatment patterns were compared between patients with and without a history of AAU. The development of AAU and its related factors were investigated using generalized estimating equations, which is a technique for longitudinal data analysis. Results: Overall, 99 (21%) out of 469 patients experienced at least one AAU attack, with 77 patients (78%) having a history of AAU and 53 patients (58% of whom had a history of AAU) experiencing AAU attacks during the follow‐up period. At baseline, patients with a history of AAU were found to be older (p =.001), be more likely to have peripheral arthritis (p <.001), have higher serum CRP levels (p =.016), have a higher frequency of sulfasalazine (SLZ) and tumor necrosis factor inhibitors (TNFi) use (p <.001 and p <.001, respectively). In the longitudinal analysis, having a history of AAU was identified as the only independent determinant of the development of AAU. Conclusions: AAU history might be a risk factor for the development of AAU attacks in patients with axSpA. Although TNFi and SLZ were prescribed more frequently to patients with a history of AAU, the effectiveness of these agents in preventing further AAU attacks was not demonstrated. [ABSTRACT FROM AUTHOR]

Published
2024
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44. Body mass index does not affect response of rituximab in patients with rheumatoid arthritis: results from the TURKBİO registry

Author

KARATAŞ, AHMET, primary, SAĞIR, RABİA PİŞKİN, additional, KOCA, SÜLEYMAN SERDAR, additional, DALKILIÇ, HÜSEYİN EDİZ, additional, CAN, GERÇEK, additional, PEHLİVAN, YAVUZ, additional, YAZICI, AYTEN, additional, İNANÇ, GÜZİDE NEVSUN, additional, ÇEFLE, AYŞE, additional, ERTÜRK, ZEYNEP, additional, AKAR, SERVET, additional, ŞENEL, SONER, additional, BİRLİK, AHMET MERİH, additional, AKKOÇ, NURULLAH, additional, and ÖNEN, FATOŞ, additional

Published
2023
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46. Second and third TNF inhibitors in European patients with axial spondyloarthritis: effectiveness and impact of the reason for switching

Author

Linde, Louise, primary, Ørnbjerg, Lykke Midtbøll, additional, Heegaard Brahe, Cecilie, additional, Wallman, Johan Karlsson, additional, Di Giuseppe, Daniela, additional, Závada, Jakub, additional, Castrejon, Isabel, additional, Díaz-Gonzalez, Federico, additional, Rotar, Ziga, additional, Tomšič, Matija, additional, Glintborg, Bente, additional, Gudbjornsson, Bjorn, additional, Geirsson, Arni Jon, additional, Michelsen, Brigitte, additional, Kristianslund, Eirik Klami, additional, Santos, Maria José, additional, Barcelos, Anabela, additional, Nordström, Dan, additional, Eklund, Kari K, additional, Ciurea, Adrian, additional, Nissen, Michael, additional, Akar, Servet, additional, Hejl Hyldstrup, Lise, additional, Krogh, Niels Steen, additional, Hetland, Merete Lund, additional, and Østergaard, Mikkel, additional

Published
2023
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47. Unintentional Monotherapy in Rheumatoid Arthritis Patients Receiving Tofacitinib and Drug Survival Rate of Tofacitinib

Author

Inanc, Nevsun, primary, Abacar, Kerem Y., additional, Ozturk, Mehmet A., additional, Tufan, Abdurrahman, additional, Karadeniz, Hazan, additional, Sari, Ismail, additional, Can, Gercek, additional, Erez, Yesim, additional, Pehlivan, Yavuz, additional, Dalkilic, Huseyin E., additional, Ocak, Tugba, additional, Cefle, Ayse, additional, Yazici, Ayten, additional, Senel, Abdurrahman S., additional, Akar, Servet, additional, Durak-Ediboğlu, Elif, additional, Koca, Suleyman S., additional, Piskin-Sagir, Rabia, additional, Yilmaz, Sema, additional, Gulcemal, Semral, additional, Soysal-Gunduz, Ozgul, additional, Basibuyuk, Canberk S., additional, Alkan, Serdar, additional, Cesur, Teoman Y., additional, and Onen, Fatos, additional

Published
2023
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50. The impact of smoking on response to tumor necrosis factor-α inhibitor treatment in patients with ankylosing spondylitis

Author

TUĞSAL, HANDAN YARKAN, primary, ARTIN, GÖKÇE KENAR, additional, CAN, GERÇEK, additional, ÇAPAR, SEDAT, additional, ZENGİN, BERRİN, additional, AKAR, SERVET, additional, DALKILIÇ, HÜSEYİN EDİZ, additional, ŞENEL, ABDURRAHMAN SONER, additional, KOCA, SÜLEYMAN SERDAR, additional, GÖKER, BERNA, additional, YAZICI, AYTEN, additional, İNANÇ, GÜZİDE NEVSUN, additional, ELLİDOKUZ, HÜLYA, additional, AKKOÇ, NURULLAH, additional, and ÖNEN, FATOŞ, additional

Published
2023
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