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Relevance. Researchers around the world are more interested to study and know the neurohormonal activation, and the role of the brain natriuretic peptide (BNP) in patients with Acute Coronary Syndrome (ACS). High concentration of BNP that is an independent predictor of repeated cardiovascular events and mortality in patients with ACS through ST elevation Goal. Study the Dynamics of BNP concentrations in patients with ACS through ST elevation with dependency on the localization of the lesion and revascularization methods.