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5. P014 Identification of Crohn’s disease immunopathotypes

Author

Robert J. B. Nibbs, Daniel R. Gaya, John J. Cole, M.I. Khan, E. MacDonald, Simon Milling, Hannah M Baer, A.M. Scott, Meera Ramanujam, U.J. Ijaz, K.A. Bain, and Annabelle Ferguson

Subjects
Crohn's disease, business.industry, medicine.medical_treatment, Gastroenterology, General Medicine, Disease, medicine.disease, Peripheral blood mononuclear cell, medicine.anatomical_structure, Immune system, Immunophenotyping, Cytokine, Immunology, medicine, Microbiome, business, B cell
Abstract

Background Crohn’s disease (CD) is a chronic inflammatory gastrointestinal condition, with globally increasing incidence. Patients with CD suffer from a loss of tolerance towards their commensal microbiota causing an aberrant immune response, occurring in a protracted relapse and remission cycle. Although a variety of frontline therapies is currently available, including targeted therapies such as biologic drugs, 30–40% of CD patients still require surgery to manage the disease. At present, the immunobiology of CD is not fully understood. However, differences in immune responses between patients might play an important role in diverse treatment responses. The aim of this study was to identify differences in peripheral and local immune responses of CD to understand differences in disease behaviour and treatment outcome. Methods Peripheral blood mononuclear cells and plasma were isolated from whole blood of a cross-sectional CD patient cohort (nCD = 12) and normal controls (NC, nNC = 28). Flow cytometry analysis and multiplex assays were used to quantify immune cell populations and cytokine levels, respectively. The local immune response was analysed by bulk RNA sequencing of mucosal colonic biopsies either from inflamed CD or normal tissue. Gene signatures were then followed up by validation in publicly deposited gene expression datasets (nCD = 36, nNC = 24), and by measurement of specific proteins using our archived samples. Results Peripheral immunophenotyping of the initial cross-sectional study displayed three different types of CD patients, characterised by either a decrease in leukocyte populations, an increase of cytokines, or a change in both. Analysis of the RNAseq data derived from colonic biopsies revealed four distinct clusters in genes associated with the immune response in CD patients. Further pathway analysis showed one cluster with an enriched B cell signature and another cluster with an elevated macrophage and neutrophil response. We utilised publicly available gene expression datasets to validate these signatures in a larger cohort and identified a selection of patients with an up-regulated pro-inflammatory macrophage response. Using correlation analysis, we suggest an immunopathotype with increased macrophage activation which is potentially associated with a more severe form of the disease. Conclusion We have identified distinct immunopathotypes in both the peripheral and local immune response of CD patients. Further investigation will correlate these distinct immune responses in CD with clinical parameters, to understand associations between diverse treatment responses and disease behaviours.

Published
2020
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6. A precision measurement of charm dimuon production in neutrino interactions from the NOMAD experiment

Author

K. Schahmaneche, C.T. Kullenberg, P. Hurst, L. Di Lella, J.-P. Mendiburu, M. Valdata-Nappi, Alessandro Cardini, J.J. Kim, R. Challis, S.A. Bunyatov, J. A. Hernando, V. Tereshchenko, Roberto Ferrari, A. Baldisseri, Th. Stolarczyk, G. Collazuol, Mario Stipčević, A. Cervera-Villanueva, C. Lachaud, Giacomo Graziani, K. Benslama, T. Weisse, B. A. Popov, M. E. Sevior, A. Lanza, F. Bobisut, A. Marchionni, M. T. Tran, Bruce Yabsley, X. Méchain, E. Gangler, H. Zaccone, C. Joseph, F. Salvatore, P. Astier, Caroline Poulsen, Domizia Orestano, Mikhail Kirsanov, R. Cousins, M. Mezzetto, M. Contalbrigo, D. Autiero, R. Petti, Stefano Lacaprara, Marco Laveder, Kai Zuber, Fergus Wilson, S.N. Tovey, J.-M. Vieira, J. M. Levy, Sergey A. Kulagin, A.M. Scott, A. Sconza, Yu. Nefedov, L. Vacavant, L. La Rotonda, Frédéric Juget, S. R. Mishra, Chiara Roda, E. Pennacchio, O.L. Klimov, H. Degaudenzi, G. J. Feldman, Fr Pastore, N. Hyett, D. Pollmann, G. F. Moorhead, D. Geppert, Luca Rebuffi, P. Riemann, Artem Chukanov, V. V. Lyubushkin, E. do Couto e Silva, P.W. Cattaneo, Ante Ljubičić, Didier Ferrere, Kevin Varvell, Barry Blumenfeld, Alexey Krasnoperov, J. Kokkonen, M. Baldo-Ceolin, M. Banner, H. Duyang, C. Conta, C. Nguyen-Mau, T. Del Prete, B. Schmidt, Sergei Gninenko, J. Dumarchez, A. Grant, H. Pessard, A. Godley, P. Nedelec, Valerio Vercesi, M. Veltri, Dmitry V. Naumov, G. Conforto, J. Long, Claus Gößling, Vyacheslav Valuev, J. Libo, Malcolm Ellis, F. Vannucci, Alexander Toropin, L. S. Peak, E. Tsesmelis, Caren Hagner, T. Schmidt, P. Zuccon, A. Kovzelev, Antonio Bueno, J. Bouchez, O. Samoylov, J.J. Gómez-Cadenas, A. Lupi, A. Placci, D. Steele, A. De Santo, L. Linssen, Marco Fraternali, Sergey Alekhin, V. Flaminio, F. J. P. Soler, F.V. Weber, T. Vinogradova, André Rubbia, E. Iacopini, Vincenzo Cavasinni, A.-M. Touchard, A. Polyarush, Achim Geiser, J. Gosset, D. Gibin, Q. Wu, U. Stiegler, G. Bassompierre, J. Rico, S. Boyd, B. Lakić, G. N. Taylor, J.M. Gaillard, J-P. Meyer, L. Camilleri, L.J. Winton, J. Ulrichs, D. Sillou, G. Sozzi, A. Guglielmi, I. Bird, X.C. Tian, Nathalie Besson, G. Vidal-Sitjes, Michel Gouanère, F. Martelli, N. Kent, A. Letessier-Selvon, Giacomo Polesello, M. Tareb-Reyes, Orestano, Domizia, National Science Foundation (US), Alfred P. Sloan Foundation, Australian Research Council, Federal Ministry of Education and Research (Germany), Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), and NOMAD

Subjects
Nuclear and High Energy Physics, Strange quark, Particle physics, Charm production, strange quark content of the nucleon, dimuon charm production, FOS: Physical sciences, Strange quark content of the nucleon, Dimuon charm production, Neutrino interactions, 01 natural sciences, Charm quark, High Energy Physics - Experiment, Nuclear physics, High Energy Physics - Experiment (hep-ex), 0103 physical sciences, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Charm (quantum number), 010306 general physics, Charged current, Physics, Quantum chromodynamics, 010308 nuclear & particles physics, Física, Deep inelastic scattering, 3. Good health, Neutrino, Nucleon, Particle Physics - Experiment
Abstract

We present our new measurement of the cross-section for charm dimuon production in neutrino iron interactions based upon the full statistics collected by the NOMAD experiment. After background subtraction we observe 15 344 charm dimuon events, providing the largest sample currently available. The analysis exploits the large inclusive charged current sample - about 9 x 10(6) events after all analysis cuts - and the high resolution NOMAD detector to constrain the total systematic uncertainty on the ratio of charm dimuon to inclusive Charged Current (CC) cross-sections to similar to 2%. We also perform a fit to the NOMAD data to extract the charm production parameters and the strange quark sea content of the nucleon within the NLO QCD approximation. We obtain a value of m(c)(m(c)) = 1.159 +/- 0.075 GeV/c(2) for the running mass of the charm quark in the (MS) over bar scheme and a strange quark sea suppression factor of kappa(s) = 0.591 +/- 0.019 at Q(2) = 20 GeV2/c(2)., We extend our grateful appreciations to the CERN SPS staff for the magnificent performance of the neutrino beam. The experiment was supported by the following agencies: ARC and DIISR of Australia, IN2P3 and CEA of France, BMBF of Germany, INFN of Italy, JINR and INR of Russia, FNSRS of Switzerland, DOE, NSF, Sloan, and Cottrell Foundations of USA, and VP Research Office of the University of South Carolina. This work was partially supported by the University of South Carolina, by the DOE grant DE-FG02-95ER40910, by the Russian Federal grant 02.740.11.5220 and MK-432.2013.2, and JINR grant 13-201-01.

Published
2013
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7. A Search for Single Photon Events in Neutrino Interactions

Author

C. Joseph, F. Salvatore, D. Geppert, P.W. Cattaneo, Ante Ljubičić, Valerio Vercesi, Dmitry V. Naumov, Marco Laveder, Th. Stolarczyk, J-P. Meyer, Caroline Poulsen, A.M. Scott, K. Benslama, E. Pennacchio, N. Hyett, Marco Fraternali, Luca Rebuffi, D. Pollmann, J. A. Hernando, L.J. Winton, A. Lanza, Artem Chukanov, M. E. Sevior, J. Ulrichs, Kevin Varvell, J. Kokkonen, M. T. Tran, J. Long, M. Mezzetto, Q. Wu, O.L. Klimov, J.-P. Mendiburu, E. Tsesmelis, Caren Hagner, Kai Zuber, G. Sozzi, U. Stiegler, Alexey Krasnoperov, A.-M. Touchard, A. Cervera-Villanueva, K. Schahmaneche, C.T. Kullenberg, P. Hurst, T. Schmidt, E. Gangler, A. Grant, H. Pessard, P. Nedelec, Roberto Ferrari, L. Di Lella, H. Degaudenzi, M. Baldo-Ceolin, M. Banner, G. J. Feldman, G. F. Moorhead, Malcolm Ellis, A. Kovzelev, M. Valdata-Nappi, Didier Ferrere, J.J. Gómez-Cadenas, V. Flaminio, Mikhail Kirsanov, R. Cousins, F. J. P. Soler, Alessandro Cardini, Yu. Nefedov, L. Vacavant, J.-M. Vieira, Alexander Toropin, L. S. Peak, C. Lachaud, J.M. Gaillard, T. Weisse, F. Bobisut, J.J. Kim, Giacomo Graziani, A. Letessier-Selvon, J. Gosset, Sergei Gninenko, Giacomo Polesello, E. do Couto e Silva, André Rubbia, G. Bassompierre, Bruce Yabsley, X. Méchain, Antonio Bueno, M. Tareb-Reyes, T. Vinogradova, D. Gibin, G. Collazuol, Mario Stipčević, A. Placci, R. Petti, R. Challis, E. Iacopini, A. Godley, A. Polyarush, A. De Santo, S.A. Bunyatov, S. Boyd, J. Dumarchez, Vyacheslav Valuev, Achim Geiser, Vincenzo Cavasinni, B. Lakić, G. N. Taylor, Michel Gouanère, C. Conta, B. Schmidt, J. Bouchez, O. Samoylov, F. Martelli, M. Veltri, F. Vannucci, M.B. Seaton, Claus Gößling, G. Conforto, N. Kent, A. Lupi, V. V. Lyubushkin, V. Tereshchenko, A. Baldisseri, D. Steele, Barry Blumenfeld, Domizia Orestano, P. Zuccon, G. Vidal-Sitjes, Drew Dimmery, M. Contalbrigo, A. Marchionni, J. M. Levy, Sergey A. Kulagin, J. Rico, A. Sconza, Frédéric Juget, Chiara Roda, L. La Rotonda, S. R. Mishra, Stefano Lacaprara, Fergus Wilson, P. Riemann, B. A. Popov, L. Camilleri, S.N. Tovey, I. Bird, X.C. Tian, Fr Pastore, L. Linssen, Sergey Alekhin, F.V. Weber, C. Nguyen-Mau, T. Del Prete, P. Astier, D. Autiero, D. Sillou, A. Guglielmi, Nathalie Besson, H. Zaccone, Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC), APC - Neutrinos, Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, NOMAD, Kullenberg, Ct, Mishra, Sr, Dimmery, D, Tian, Xc, Autiero, D, Gninenko, S, Rubbia, A, Alekhin, S, Astier, R, Baldisseri, A, Baldo Ceolin, M, Banner, M, Bassompierre, G, Benslama, K, Besson, N, Bird, I, Blumenfeld, B, Bobisut, F, Bouchez, J, Boyd, S, Bueno, A, Bunyatov, S, Camilleri, L, Cardini, A, Cattaneo, Pw, Cavasinni, V, Cervera Villanueva, A, Challis, R, Chukanov, A, Collazuol, G, Conforto, G, Conta, C, Contalbrigo, M, Cousins, R, Degaudenzi, H, De Santo, A, Del Prete, T, Di Lella, L, Silva, Ede, Dumarchez, J, Ellis, M, Feldman, Gj, Ferrari, R, Ferrere, D, Flaminio, V, Fraternali, M, Gaillard, Jm, Gangler, E, Geiser, A, Geppert, D, Gibin, D, Godley, A, Gomez Cadenas, Jj, Gosset, J, Gossling, C, Gouanere, M, Grant, A, Graziani, G, Guglielmi, A, Hagner, C, Hernando, J, Hurst, P, Hyett, N, Iacopini, E, Joseph, C, Juget, F, Kent, N, Klimov, O, Kokkonen, J, Kovzelev, A, Krasnoperov, A, Kim, Jj, Kirsanov, M, Kulagin, S, Lacaprara, S, Lachaud, C, Lakic, B, Lanza, A, La Rotonda, L, Laveder, M, Letessier Selvon, A, Levy, Jm, Ling, J, Linssen, L, Ljubicic, A, Long, J, Lupi, A, Lyubushkin, V, Marchionni, A, Martelli, F, Mechain, X, Mendiburu, Jp, Meyer, Jp, Mezzetto, M, Moorhead, Cf, Naumov, D, Nedelec, R, Nefedov, Y, Nguyen Mau, C, Orestano, Domizia, Pastore, F, Peak, L, Pennacchio, E, Pessard, H, Petti, R, Placci, A, Polesello, G, Pollmann, D, Polyarush, A, Poulsen, C, Popov, B, Rebuffi, L, Rico, J, Riemann, P, Roda, C, Salvatore, F, Samoylov, O, Schahmaneche, K, Schmidt, B, Schmidt, T, Sconza, A, Scott, Am, Seaton, Mb, Sevior, M, Sillou, D, Soler, Fjr, Sozzi, G, Steele, D, Stiegler, U, Stipcevic, M, Stolarczyk, T, Tareb Reyes, M, Taylor, Gn, Tereshchenko, V, Toropin, A, Touchard, Am, Tovey, Sn, Tran, Mt, Tsesmelis, E, Ulrichs, J, Vacavant, L, Valdata Nappi, M, Valuev, V, Vannucci, F, Varvell, Ke, Veltri, M, Vercesi, V, Vidal Sitjes, G, Vieira, Jm, Vinogradova, T, Weber, Fv, Weissee, T, Wilson, Ff, Winton, Lj, Wu, Q, Yabsley, Bd, Zaccone, H, Zuber, K, Zuccon, R., Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Annecy de Physique des Particules (LAPP/Laboratoire d'Annecy-le-Vieux de Physique des Particules), AstroParticule et Cosmologie (APC (UMR_7164)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), and Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Nuclear and High Energy Physics, Particle physics, Photon, FOS: Physical sciences, 01 natural sciences, High Energy Physics - Experiment, Nuclear physics, MiniBooNE, Neutral current, High Energy Physics - Experiment (hep-ex), Pion, High Energy Physics - Phenomenology (hep-ph), 0103 physical sciences, Neutrino, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Coherent, Single photon, 010306 general physics, Charged current, Physics, 010308 nuclear & particles physics, Física, Deep inelastic scattering, single photon, neutrino, neutral current, coherent, pion, High Energy Physics - Phenomenology, [PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph], High Energy Physics::Experiment, Event (particle physics), Particle Physics - Experiment
Abstract

We present a search for neutrino induced events containing a single, exclusive photon using data from the NOMAD experiment at the CERN SPS where the average energy of the neutrino flux is ≃25 GeV. The search is motivated by an excess of electron-like events in the 200-475 MeV energy region as reported by the MiniBooNE experiment. In NOMAD, photons are identified via their conversion to e + e - in an active target embedded in a magnetic field. The background to the single photon signal is dominated by the asymmetric decay of neutral pions produced either in a coherent neutrino-nucleus interaction, or in a neutrino-nucleon neutral current deep inelastic scattering, or in an interaction occurring outside the fiducial volume. All three backgrounds are determined in situ using control data samples prior to opening the 'signal-box'. In the signal region, we observe 155 events with a predicted background of 129.2±8.5±3.3. We interpret this as null evidence for excess of single photon events, and set a limit. Assuming that the hypothetical single photon has a momentum distribution similar to that of a photon from the coherent π 0 decay, the measurement yields an upper limit on single photon events, Physics Letters B, 706 (4-5), ISSN:0370-2693, ISSN:0031-9163, ISSN:1873-2445

Published
2012
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8. Brillouin-induced four-wave mixing using beams with gaussian temporal and spatial profiles

Author

Kevin D. Ridley, A.M. Scott, and D. C. Jones

Subjects
Physics, business.industry, Pulse (signal processing), Gaussian, Pulse duration, Optical field, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials, symbols.namesake, Optics, Signal beam, symbols, M squared, Electrical and Electronic Engineering, Physical and Theoretical Chemistry, business, Beam (structure), Gaussian beam
Abstract

Numerical solutions are obtained to the coupled acoustic and optical field equations for the case where the signal beam is anti-Stokes shifted relative to the pump beam. It is shown that when gaussian temporal pulse profiles are used, the theoretically pre-dicted reflectivity and efficiency are greatly modified owing to the strong dependence of conjugate build up time on signal and pump beam intensity. The effect of varying pulse length, phonon lifetime, and signal-pump timing is studied. Finally the effect of gaussian spatial profiles is considered.

Published
1992
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9. A measurement of coherent neutral pion production in neutrino neutral current interactions in the NOMAD experiment

Author

Marco Fraternali, A. Placci, J. A. Hernando, M. Mezzetto, A. De Santo, Alexander Toropin, Kai Zuber, G. Bassompierre, S. Boyd, B. Lakić, G. N. Taylor, L. S. Peak, O.L. Klimov, V. Flaminio, F. J. P. Soler, J. Long, K. Benslama, T. Vinogradova, F. Bobisut, Antonio Bueno, A.-M. Touchard, A. Cervera-Villanueva, Kevin Varvell, L. Camilleri, Vyacheslav Valuev, J.M. Gaillard, C. Lachaud, Giacomo Graziani, V. V. Lyubushkin, M. T. Tran, D. Steele, Nathalie Besson, E. Gangler, Mikhail Kirsanov, R. Cousins, Barry Blumenfeld, A.M. Scott, A. Grant, H. Pessard, P. Nedelec, T. Weisse, J. Kokkonen, Malcolm Ellis, R. Challis, J.-P. Mendiburu, Q. Wu, S.A. Bunyatov, A. Marchionni, J.-M. Vieira, U. Stiegler, E. Pennacchio, I. Bird, D. Geppert, J. Rico, P.W. Cattaneo, Ante Ljubičić, F. Vannucci, E. do Couto e Silva, N. Hyett, R. Petti, D. Pollmann, P. Astier, J. Bouchez, L. Linssen, J.J. Gómez-Cadenas, André Rubbia, O. Samoylov, Alessandro Cardini, X.C. Tian, A. Baldisseri, Sergey Alekhin, Roberto Ferrari, V. Tereshchenko, F. Salvatore, B. A. Popov, Alexey Krasnoperov, D. Autiero, D. Sillou, Yu. Nefedov, L. Vacavant, F.V. Weber, Frédéric Juget, Chiara Roda, P. Zuccon, J. Gosset, A. Lupi, E. Iacopini, Caroline Poulsen, H. Zaccone, Luca Rebuffi, Artem Chukanov, Bruce Yabsley, Claus Gößling, X. Méchain, A. Guglielmi, D. Gibin, C. Joseph, Vincenzo Cavasinni, G. Vidal-Sitjes, M. Baldo-Ceolin, A. Polyarush, C. Conta, B. Schmidt, H. Degaudenzi, G. J. Feldman, Achim Geiser, G. F. Moorhead, G. Conforto, J. Dumarchez, Marco Laveder, Didier Ferrere, Th. Stolarczyk, M. Banner, Valerio Vercesi, Dmitry V. Naumov, M. E. Sevior, K. Schahmaneche, Sergei Gninenko, C.T. Kullenberg, P. Hurst, L. Di Lella, M. Valdata-Nappi, E. Tsesmelis, Caren Hagner, Domizia Orestano, J.J. Kim, T. Schmidt, A. Kovzelev, A. Godley, M. Contalbrigo, J. M. Levy, Sergey A. Kulagin, G. Collazuol, Mario Stipčević, M. Veltri, J-P. Meyer, L.J. Winton, A. Sconza, J. Ulrichs, M.B. Seaton, L. La Rotonda, S. R. Mishra, A. Lanza, G. Sozzi, P. Riemann, Stefano Lacaprara, Fergus Wilson, A. Letessier-Selvon, Giacomo Polesello, M. Tareb-Reyes, Michel Gouanère, F. Martelli, N. Kent, C. Nguyen-Mau, T. Del Prete, S.N. Tovey, Fr Pastore, Kullenberg, Ct, Mishra, Sr, Seaton, Mb, Kim, Jj, Tian, Xc, Scott, Am, Kirsanov, M, Petti, R, Alekhin, S, Astier, P, Autiero, D, Baldisseri, A, Baldo Ceolin, M, Banner, M, Bassompierre, G, Benslama, K, Besson, N, Bird, I, Blumenfeld, B, Bobisut, F, Bouchez, J, Boyd, S, Bueno, A, Bunyatov, S, Camilleri, L, Cardini, A, Cattaneo, Pw, Cavasinni, V, Cervera Villanueva, A, Challis, R, Chukanov, A, Collazuol, G, Conforto, G, Conta, C, Contalbrigo, M, Cousins, R, Degaudenzi, H, De Santo, A, Del Prete, T, Di Lella, L, Silva, Ede, Dumarchez, J, Ellis, M, Feldman, Gj, Ferrari, R, Ferrere, D, Flaminio, V, Fraternali, M, Gaillard, Jm, Gangler, E, Geiser, A, Geppert, D, Gibin, D, Gninenko, S, Godley, A, Gomez Cadenas, Jj, Gosset, J, Gossling, C, Gouanere, M, Grant, A, Graziani, G, Guglielmi, A, Hagner, C, Hernando, J, Hurst, P, Hyett, N, Iacopini, E, Joseph, C, Juget, F, Kent, N, Klimov, O, Kokkonen, J, Kovzelev, A, Krasnoperov, A, Kulagin, S, Lacaprara, S, Lachaud, C, Lakic, B, Lanza, A, La Rotonda, L, Laveder, M, Letessier Selvon, A, Levy, Jm, Ling, J, Linssen, L, Ljubicic, A, Long, J, Lupi, A, Lyubushkin, V, Marchionni, A, Martelli, F, Mechain, X, Mendiburu, Jp, Meyer, Jp, Mezzetto, M, Moorhead, Gf, Naumov, D, Nedelec, P, Nefedov, Y, Nguyen Mau, C, Orestano, Domizia, Pastore, F, Peak, L, Pennacchio, E, Pessard, H, Placci, A, Polesello, G, Pollmann, D, Polyarush, A, Poulsen, C, Popov, B, Rebuffi, L, Rico, J, Riemann, P, Roda, C, Rubbia, A, Salvatore, F, Samoylov, O, Schahmaneche, K, Schmidt, B, Schmidt, T, Sconza, A, Sevior, M, Sillou, D, Soler, Fjp, Sozzi, G, Steele, D, Stiegler, U, Stipcevic, M, Stolarczyk, T, Tareb Reyes, M, Taylor, Gn, Tereshchenko, V, Toropin, A, Touchard, Am, Tovey, Sn, Tran, Mt, Tsesmelis, E, Ulrichs, J, Vacavant, L, Valdata Nappi, M, Valuev, V, Vannucci, F, Varvell, Ke, Veltri, M, Vercesi, V, Vidal Sitjes, G, Vieira, Jm, Vinogradova, T, Weber, Fv, Weisse, T, Wilson, Ff, Winton, Lj, Wu, Q, Yabsley, Bd, Zaccone, H, Zuber, K, Zuccon, P., Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Annecy de Physique des Particules (LAPP/Laboratoire d'Annecy-le-Vieux de Physique des Particules), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), APC - Neutrinos, AstroParticule et Cosmologie (APC (UMR_7164)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), NOMAD, Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC), Laboratoire d'Annecy de Physique des Particules (LAPP), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Particle physics, Nuclear and High Energy Physics, FOS: Physical sciences, 7. Clean energy, 01 natural sciences, High Energy Physics - Experiment, Nuclear physics, High Energy Physics - Experiment (hep-ex), Pion, Coherent pion neutrino neutral current, 0103 physical sciences, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], 010306 general physics, Nuclear Experiment, Charged current, Physics, Range (particle radiation), Large Hadron Collider, Neutral current, 010308 nuclear & particles physics, Scattering, Física, Deep inelastic scattering, coherent pion, neutrino, neutral current, High Energy Physics::Experiment, Neutrino, Particle Physics - Experiment
Abstract

We present a study of exclusive neutral pion production in neutrino-nucleus Neutral Current interactions using data from the NOMAD experiment at the CERN SPS. The data correspond to $1.44 \times 10^6$ muon-neutrino Charged Current interactions in the energy range $2.5 \leq E_{\nu} \leq 300$ GeV. Neutrino events with only one visible $\pi^0$ in the final state are expected to result from two Neutral Current processes: coherent $\pi^0$ production, {\boldmath $\nu + {\cal A} \to \nu + {\cal A} + \pi^0$} and single $\pi^0$ production in neutrino-nucleon scattering. The signature of coherent $\pi^0$ production is an emergent $\pi^0$ almost collinear with the incident neutrino while $\pi^0$'s produced in neutrino-nucleon deep inelastic scattering have larger transverse momenta. In this analysis all relevant backgrounds to the coherent $\pi^0$ production signal are measured using data themselves. Having determined the backgrounds, and using the Rein-Sehgal model for the coherent $\pi^0$ production to compute the detection efficiency, we obtain {\boldmath $4630 \pm 522 (stat) \pm 426 (syst)$} corrected coherent-$\pi^0$ events with $E_{\pi^0} \geq 0.5$ GeV. We measure {\boldmath $\sigma (\nu {\cal A} \to \nu {\cal A} \pi^0) = [ 72.6 \pm 8.1(stat) \pm 6.9(syst) ] \times 10^{-40} cm^2/nucleus$}. This is the most precise measurement of the coherent $\pi^0$ production to date., Comment: 23 pages, 9 figures, accepted for publication in Phys. Lett. B

Published
2009
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10. Asynchronous on-Chip Communication: Explorations on the Intel PXA27x Processor Peripheral Bus

Author

M.E. Schuelein, A.M. Scott, Marly Roncken, A. Bardsley, D.L. Jackson, John Mawer, J. Bainbridge, and Jin-Jer Hwan

Subjects
Engineering, Network on a chip, Asynchronous communication, business.industry, Globally asynchronous locally synchronous, Embedded system, Time to market, Peripheral bus, Timing closure, business, Back-side bus, System bus
Abstract

For today's SoC designer, on-die variation, clock distribution, timing closure, and power concerns confront the desire to get products to market quicker. Each new process generation makes the challenge greater as process skews, complexity, and frequency become more onerous. This is particularly true for signals that have to travel across larger portions of a chip such as clocks and buses. In this paper, we examine the use of GALS (Globally Asynchronous, Locally Synchronous) [Chapiro, 1985] techniques to address on-chip communication between different synchronous modules on a bus. We explore issues related to validation, module interfaces and tool flows, while looking at advantages in power savings, timing closure and Time-to-Market/Time-to-Money (TTM). Our exploration vehicle is the IntelregPXA27x Peripheral Bus (PB) - a common interface for connecting peripherals on PXA27x and related processor families in Intel's cellular and handheld application and communication domain.

Published
2007
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11. Phase conjugate beam steering using a multi-pass amplifier system with high gain

Author

A.P.G. Davies and A.M. Scott

Subjects
Physics, High-gain antenna, Conjugate beam method, Optics, business.industry, Amplifier, Beam steering, Phase (waves), Physics::Accelerator Physics, Laser beam quality, business, Beam parameter product, Power (physics)
Abstract

Summary form only given. We show that one can modify a multi-pass amplifier scheme to provide phase conjugate beam steering over a useful angular range. Experiments demonstrate a scalable architecture in which phase conjugate beam control provides a method for manipulating high power beams using components designed for low power operation.

Published
2002
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12. A 12-pass laser amplifier scheme for achieving efficient high gain amplification

Author

A.M. Scott, A.P.G. Davies, and H. Cook

Subjects
Physics, Optical amplifier, business.industry, Amplifier, Optical performance monitoring, Laser, Multiplexing, Optical parametric amplifier, law.invention, Optics, law, Semiconductor optical gain, business, Phase conjugation
Abstract

Summary form only given.If one wishes to extract energy from an amplifier one usually requires substantial input energies, and the net gain is modest. Gain and energy extraction can be improved by double passing an amplifier system, often using nonlinear optical phase conjugation to compensate for aberrations. In amplifier systems it is often convenient to use relay imaging, using an intermediate telescope. In this paper we introduce an optical element to intercept beams propagating in a self-imaging system and introduce an angle multiplexing arrangement. This makes it possible to pass a beam through an amplifier many times. The technique is generic and applicable to a variety of laser amplifiers.

Published
2000
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13. Design, modelling and evaluation of micro-mirrors

Author

A.M. Scott, R.A. Wilson, R.J.T. Bunyan, and David O. King

Subjects
Engineering, Range (mathematics), Fabrication, business.industry, Process (computing), Control engineering, Material properties, business, Key issues, Finite element method
Abstract

The use of a range of modelling techniques in the design of electrostatically actuated micromirrors has been demonstrated. Both simple 1D modelling and full 3D finite element techniques have their own merits and neither can be neglected at the cost of the other. However, as in the case of any modelling exercise, the data produced is only as good as the input information. Consequently, if the concept of the virtual fabrication laboratory is to be applied to the design of micromachined structures for MEOMS, accurate knowledge of both material properties and process tolerances remain key issues. (3 pages)

Published
1999
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14. Stimulated Brillouin Scattering Phase-Locked Phase Conjugation

Author

A.M. Scott, K.D. Ridley, and P. Sean

Subjects
Four-wave mixing, Materials science, Brillouin scattering, Phase (waves), Laser power scaling, Noise level, Phase conjugation, Molecular physics, Laser beams
Abstract

A new loop geometry was recently investigated for SBS phase conjugation and was shown to greatly improve the stability of the phase conjugation process by eliminating phase jumps which can degrade the stability and fidelity [1]. The loop increases the coherence length of the laser output [2], making it suitable for heterodyne laser radar.

Published
1996
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15. Improved modeling studies of Brillouin enhanced four-wave mixing

Author

A.M. Scott and P. Waggott

Subjects
Materials science, business.industry, Nonlinear optics, Condensed Matter Physics, Atomic and Molecular Physics, and Optics, Intensity (physics), Computational physics, Reduction (complexity), Brillouin zone, Four-wave mixing, Optics, Brillouin scattering, Reflection (physics), Electrical and Electronic Engineering, business, Mixing (physics)
Abstract

An improved algorithm is used to integrate the full equations for Brillouin enhanced four-wave mixing (including propagation terms). The improved algorithm produces a correction of around 10% and a reduction in the computed value of the conjugate intensity compared with earlier published data. >

Published
1990
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16. Mediastinal staging of suspected non small cell lung cancer comparing FDG PET and computed tomography with histology

Author

A.G. Royse, J. G. Chan, O. Poinlon, G.F. Egan, A.M. Scott, C. P. Clarke, S.U. Bedangien, G.J. O'Keefe, Henri Tochon-Danguy, W.J. Mckay, D.L. Thomas, and S. R. Knight

Subjects
medicine.medical_specialty, medicine.diagnostic_test, business.industry, Computed tomography, Histology, medicine.disease, Mediastinal staging, medicine, Non small cell, Radiology, Cardiology and Cardiovascular Medicine, Lung cancer, business, Nuclear medicine
Published
1996
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17. Myriotrichia claviformis

Author

A.M. Scott, A.M. Scott, A.M. Scott, and A.M. Scott

Abstract

Algae, http://name.umdl.umich.edu/IC-HERB00IC-X-636733%5DMICH-A-636733, https://quod.lib.umich.edu/cgi/i/image/api/thumb/herb00ic/636733/MICH-A-636733/!250,250, The University of Michigan Library provides access to these materials for educational and research purposes. Some materials may be protected by copyright. If you decide to use any of these materials, you are responsible for making your own legal assessment and securing any necessary permission. If you have questions about the collection, please contact the Herbarium professional staff: herb-dlps-help@umich.edu. If you have concerns about the inclusion of an item in this collection, please contact Library Information Technology: libraryit-info@umich.edu., https://www.lib.umich.edu/about-us/policies/copyright-policy

Published
1940

18. Hummia onusta

Author

A.M. Scott, A.M. Scott, A.M. Scott, and A.M. Scott

Abstract

Algae, http://name.umdl.umich.edu/IC-HERB00IC-X-635881%5DMICH-A-635881, https://quod.lib.umich.edu/cgi/i/image/api/thumb/herb00ic/635881/MICH-A-635881/!250,250, The University of Michigan Library provides access to these materials for educational and research purposes. Some materials may be protected by copyright. If you decide to use any of these materials, you are responsible for making your own legal assessment and securing any necessary permission. If you have questions about the collection, please contact the Herbarium professional staff: herb-dlps-help@umich.edu. If you have concerns about the inclusion of an item in this collection, please contact Library Information Technology: libraryit-info@umich.edu., https://www.lib.umich.edu/about-us/policies/copyright-policy

Published
1940

19. Ectocarpus siliculosus

Author

A.M. Scott, A.M. Scott, A.M. Scott, and A.M. Scott

Abstract

Algae, http://name.umdl.umich.edu/IC-HERB00IC-X-635170%5DMICH-A-635170, https://quod.lib.umich.edu/cgi/i/image/api/thumb/herb00ic/635170/MICH-A-635170/!250,250, The University of Michigan Library provides access to these materials for educational and research purposes. Some materials may be protected by copyright. If you decide to use any of these materials, you are responsible for making your own legal assessment and securing any necessary permission. If you have questions about the collection, please contact the Herbarium professional staff: herb-dlps-help@umich.edu. If you have concerns about the inclusion of an item in this collection, please contact Library Information Technology: libraryit-info@umich.edu., https://www.lib.umich.edu/about-us/policies/copyright-policy

Published
1940

20. Ulva flexuosa

Author

A.M. Scott, A.M. Scott, A.M. Scott, and A.M. Scott

Abstract

Algae, http://name.umdl.umich.edu/IC-HERB00IC-X-734140%5DMICH-A-734140, https://quod.lib.umich.edu/cgi/i/image/api/thumb/herb00ic/734140/MICH-A-734140/!250,250, The University of Michigan Library provides access to these materials for educational and research purposes. Some materials may be protected by copyright. If you decide to use any of these materials, you are responsible for making your own legal assessment and securing any necessary permission. If you have questions about the collection, please contact the Herbarium professional staff: herb-dlps-help@umich.edu. If you have concerns about the inclusion of an item in this collection, please contact Library Information Technology: libraryit-info@umich.edu., https://www.lib.umich.edu/about-us/policies/copyright-policy

Published
1941

21. Ulva clathrata

Author

A.M. Scott, A.M. Scott, A.M. Scott, and A.M. Scott

Abstract

Algae, http://name.umdl.umich.edu/IC-HERB00IC-X-733292%5DMICH-A-733292, https://quod.lib.umich.edu/cgi/i/image/api/thumb/herb00ic/733292/MICH-A-733292/!250,250, The University of Michigan Library provides access to these materials for educational and research purposes. Some materials may be protected by copyright. If you decide to use any of these materials, you are responsible for making your own legal assessment and securing any necessary permission. If you have questions about the collection, please contact the Herbarium professional staff: herb-dlps-help@umich.edu. If you have concerns about the inclusion of an item in this collection, please contact Library Information Technology: libraryit-info@umich.edu., https://www.lib.umich.edu/about-us/policies/copyright-policy

Published
1941

22. Ulva fenestrata

Author

A.M. Scott, A.M. Scott, A.M. Scott, and A.M. Scott

Abstract

Algae, http://name.umdl.umich.edu/IC-HERB00IC-X-733681%5DMICH-A-733681, https://quod.lib.umich.edu/cgi/i/image/api/thumb/herb00ic/733681/MICH-A-733681/!250,250, The University of Michigan Library provides access to these materials for educational and research purposes. Some materials may be protected by copyright. If you decide to use any of these materials, you are responsible for making your own legal assessment and securing any necessary permission. If you have questions about the collection, please contact the Herbarium professional staff: herb-dlps-help@umich.edu. If you have concerns about the inclusion of an item in this collection, please contact Library Information Technology: libraryit-info@umich.edu., https://www.lib.umich.edu/about-us/policies/copyright-policy

Published
1940

23. Batophora oerstedii

Author

A.M. Scott, A.M. Scott, A.M. Scott, and A.M. Scott

Abstract

Algae, http://name.umdl.umich.edu/IC-HERB00IC-X-678812%5DMICH-A-678812, https://quod.lib.umich.edu/cgi/i/image/api/thumb/herb00ic/678812/MICH-A-678812/!250,250, The University of Michigan Library provides access to these materials for educational and research purposes. Some materials may be protected by copyright. If you decide to use any of these materials, you are responsible for making your own legal assessment and securing any necessary permission. If you have questions about the collection, please contact the Herbarium professional staff: herb-dlps-help@umich.edu. If you have concerns about the inclusion of an item in this collection, please contact Library Information Technology: libraryit-info@umich.edu., https://www.lib.umich.edu/about-us/policies/copyright-policy

Published
1954

24. Polysiphonia subtilissima

Author

A.M. Scott, A.M. Scott, A.M. Scott, and A.M. Scott

Abstract

Algae, http://name.umdl.umich.edu/IC-HERB00IC-X-668796%5DMICH-A-668796, https://quod.lib.umich.edu/cgi/i/image/api/thumb/herb00ic/668796/MICH-A-668796/!250,250, The University of Michigan Library provides access to these materials for educational and research purposes. Some materials may be protected by copyright. If you decide to use any of these materials, you are responsible for making your own legal assessment and securing any necessary permission. If you have questions about the collection, please contact the Herbarium professional staff: herb-dlps-help@umich.edu. If you have concerns about the inclusion of an item in this collection, please contact Library Information Technology: libraryit-info@umich.edu., https://www.lib.umich.edu/about-us/policies/copyright-policy

Published
1941

25. Polysiphonia subtilissima

Author

A.M. Scott, A.M. Scott, A.M. Scott, and A.M. Scott

Abstract

Algae, http://name.umdl.umich.edu/IC-HERB00IC-X-668795%5DMICH-A-668795, https://quod.lib.umich.edu/cgi/i/image/api/thumb/herb00ic/668795/MICH-A-668795/!250,250, The University of Michigan Library provides access to these materials for educational and research purposes. Some materials may be protected by copyright. If you decide to use any of these materials, you are responsible for making your own legal assessment and securing any necessary permission. If you have questions about the collection, please contact the Herbarium professional staff: herb-dlps-help@umich.edu. If you have concerns about the inclusion of an item in this collection, please contact Library Information Technology: libraryit-info@umich.edu., https://www.lib.umich.edu/about-us/policies/copyright-policy

Published
1940

26. Compsopogon indet

Author

A.M. Scott, A.M. Scott, A.M. Scott, and A.M. Scott

Abstract

Algae, http://name.umdl.umich.edu/IC-HERB00IC-X-649158%5DMICH-A-649158, https://quod.lib.umich.edu/cgi/i/image/api/thumb/herb00ic/649158/MICH-A-649158/!250,250, The University of Michigan Library provides access to these materials for educational and research purposes. Some materials may be protected by copyright. If you decide to use any of these materials, you are responsible for making your own legal assessment and securing any necessary permission. If you have questions about the collection, please contact the Herbarium professional staff: herb-dlps-help@umich.edu. If you have concerns about the inclusion of an item in this collection, please contact Library Information Technology: libraryit-info@umich.edu., https://www.lib.umich.edu/about-us/policies/copyright-policy

Published
1940

27. Compsopogon indet

Author

A.M. Scott, A.M. Scott, A.M. Scott, and A.M. Scott

Abstract

Algae, http://name.umdl.umich.edu/IC-HERB00IC-X-649159%5DMICH-A-649159, https://quod.lib.umich.edu/cgi/i/image/api/thumb/herb00ic/649159/MICH-A-649159/!250,250, The University of Michigan Library provides access to these materials for educational and research purposes. Some materials may be protected by copyright. If you decide to use any of these materials, you are responsible for making your own legal assessment and securing any necessary permission. If you have questions about the collection, please contact the Herbarium professional staff: herb-dlps-help@umich.edu. If you have concerns about the inclusion of an item in this collection, please contact Library Information Technology: libraryit-info@umich.edu., https://www.lib.umich.edu/about-us/policies/copyright-policy

Published
1941

28. Stigeoclonium indet.

Author

A.M. Scott, A.M. Scott, A.M. Scott, and A.M. Scott

Abstract

Algae, http://name.umdl.umich.edu/IC-HERB00IC-X-732174%5DMICH-A-732174, https://quod.lib.umich.edu/cgi/i/image/api/thumb/herb00ic/732174/MICH-A-732174/!250,250, The University of Michigan Library provides access to these materials for educational and research purposes. Some materials may be protected by copyright. If you decide to use any of these materials, you are responsible for making your own legal assessment and securing any necessary permission. If you have questions about the collection, please contact the Herbarium professional staff: herb-dlps-help@umich.edu. If you have concerns about the inclusion of an item in this collection, please contact Library Information Technology: libraryit-info@umich.edu., https://www.lib.umich.edu/about-us/policies/copyright-policy

29. Stigeoclonium indet.

Author

A.M. Scott, A.M. Scott, A.M. Scott, and A.M. Scott

Abstract

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30. The characterization of patchy mixtures

Author

A.M. Scott and J. Bridgwater

Subjects
Work (thermodynamics), Correlation coefficient, Chemistry, Applied Mathematics, General Chemical Engineering, Sample (material), Isotropy, Analytical chemistry, Thermodynamics, Contrast (statistics), General Chemistry, Composition (combinatorics), Industrial and Manufacturing Engineering, Characterization (materials science), Sample size determination
Abstract

Two-component isotropic mixtures may be characterized by a correlation coefficient between sample compositions. Previous studies of this type have often been hard to use in those practical situations in which it is clear that sample composition depends on sample size. Alternatively the composition-distance relationship has not been fully preserved. Here it is shown that a more satisfactory characterization is obtained by basing a correlation coefficient upon elements of the mixture, an element being much smaller than the smallest constituent unit capable of independent movement and thus having the composition of one of the pure components. This correlation coefficient is independent of element size and may be used to provide a precise description of the statistical properties of the mixture. For example the variance of macroscopic circular and spherical samples may be deduced as may the correlation coefficient for linear macroscopic samples. The theory leads to a discussion of other work, of free space in particulate mixtures and of the necessary number of parameters required in the correlation coefficient. A practical result is that the variance of samples taken from a non-random isotropic mixture becomes inversely proportional to sample volume if the samples are sufficiently large, in contrast to work by Bourne and Landry.

Published
1974
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31. Reduction of inbreeding in a natural herd of horses

Author

P. Malkas, A.M. Scott, P. Duncan, C. Feh, and J.C. Gleize

Subjects
Sexual behavior, Natural population growth, Ecology, animal diseases, Herd, Zoology, Animal Science and Zoology, Consanguinity, Biology, Mating, Inbreeding, Ecology, Evolution, Behavior and Systematics
Abstract

A genetically-isolated herd of 14 Camargue horses left unmanaged for 6 years produced 58 living foals and developed a social system similar to that of wild horses. Paternity of the foals was determined by blood-typing. Inbreeding coefficients were calculated and were lower than expected on the hypothesis that mating was random with respect to relatedness. The horses showed reduced levels of sexual behaviour with members of their entourage as juveniles — mother, herd stallion and maternal siblings.

Published
1984
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32. Solids flow velocity profiles in mass flow hoppers

Author

A.M. Scott, E. De Hilster, H.G. Polderman, and J. Boom

Subjects
Classical mechanics, Flow velocity, Distribution (number theory), Applied Mathematics, General Chemical Engineering, Mass flow, General Chemistry, Mechanics, Plasticity theory, Industrial and Manufacturing Engineering, Mathematics
Abstract

A mathematical model is presented for the solids velocity distribution in mass flow hoppers; it is based on classical plasticity theory. The analytical solutions are in good agreement with the results of experiments performed with sand and organic prills in model hoppers of 0.11 and 0.60 m diameter.

Published
1987
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33. Self-diffusion of spherical particles in a simple shear apparatus

Author

J. Bridgwater and A.M. Scott

Subjects
Shearing (physics), Simple shear, Self-diffusion, Classical mechanics, Materials science, General Chemical Engineering, Perpendicular, Mechanics, Strain rate, Granular material, Magnetosphere particle motion, Dimensionless quantity
Abstract

When a cohesionless granular material is strained, blocks of the material move coherently, while between these blocks are found narrow regions, typically 10 particle diameters thick, of high strain rate, which are known as failure zones. In such zones the material is dilated and relative particle motion occurs. This work examines irregular particle movement in a failure zone developed in a simple shear cell. The cell was loaded with regions of red and black material separated by a plane interface. The material was then sheared and the final distribution of the two colours was recorded photographically. Particle movement in three mutually perpendicular directions was examined by varying the initial interface orientation. The results were approximately in accordance with a diffusive model, although the coefficient in the direction of shearing was about twice that in the other two directions. Dimensionless diffusion coefficients showed little change when the normal stress was increased by a factor of 2 built1 2 or when the rate of strain was increased by a factor of 4. Changes to the base of the cell also have little effect, and it is deduced that true material results were obtained.

Published
1976
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34. Interparticle percolation: lateral and axial diffusion coefficients

Author

A.M. Scott, J. Bridgwater, and M.H. Cooke

Subjects
Simple shear, High strain rate, Molecular diffusion, Condensed matter physics, Chemistry, General Chemical Engineering, Percolation, Lateral diffusion, Particle, Axial diffusion, Dimensionless quantity
Abstract

Interparticle percolation is a fundamental process that controls the detailed distribution of particles in free-flowing mixtures and of aggregates in cohesive ones. Percolation is the drainage of one species through another in regions of high strain rate, the failure zones. Here it is shown how lateral diffusion can be studied in a simple shear cell. Furthermore, axial diffusion, which is controlled by the variability in percolation velocity, can be examined. The dimensionless lateral and axial diffusion coefficients are found to be controlled principally by the ratio of the diameter of the percolating particle to that of the bulk particles.

Published
1978
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35. Factors affecting the beam quality in nearly degenerate four wave mixing

Author

A.M. Scott

Subjects
Physics, business.industry, Degenerate energy levels, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials, Four-wave mixing, Optics, Quality (physics), Light beam, Laser beam quality, Electrical and Electronic Engineering, Physical and Theoretical Chemistry, business, Phase conjugation, Beam (structure), Mixing (physics)
Abstract

The quality of phase conjugation by nearly degenerate four-wave mixing is assessed by calculating the direction and divergence of a beam produced by three overlapping gaussian beams. The effect of pump misalignment and thickness of the nonlinear zone are considered, and the conditions for good conjugation are determined. In the high reflectivity regime the conditions for good quality conjugation can be estimated using heuristic arguments.

Published
1987
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36. A bubble model describing the influence of internals on gas fluidization

Author

C.E. Brakel, A.M. Scott, K. Chandrasekharan, R. Samson, and P. Veenstra

Subjects
Superficial velocity, Materials science, Applied Mathematics, General Chemical Engineering, Bubble, Multiphase flow, Flow (psychology), Baffle, General Chemistry, Mechanics, Industrial and Manufacturing Engineering, Physics::Fluid Dynamics, Mass transfer, Fluidization, Liquid bubble, Simulation
Abstract

Pipes, baffles, perforated plates, and other types of internals are often employed in multiphase flow systems in order to improve important performance parameters such as staging, bubble size and mass transfer. Previous studies in our laboratory on gas/liquid bubble flow (Roes et al., 1984) have demonstrated the efficacy of horizontal perforated plates with a free area of ca. 70 % for reducing bubble size. We have now employed the same type of plates for the fluidization, by air, of a Geldart class-A powder in beds of 0.3 and 0.6 m diameter. The bubble hold-up was found to be larger than in the same bed without internals at the same gas superficial velocity. The solids dispersion coefficient was reduced by a factor of about 5 by the action of the internals. The experimental observations are quantitatively described with a mathematical model containing only one adjustable parameter, namely the maximum stable bubble size. The success of this model suggests that the effect of the internals can be described solely in terms of a reduction in maximum bubble size. The model can furthermore be used for scaling studies, for predicting the effect of an increase in equipment size on fluidization properties such as bubble hold-up and axial solids dispersion.

Published
1988
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37. Efficient phase conjugation by Brillouin enhanced four wave mixing

Author

A.M. Scott

Subjects
Physics, business.industry, Phase (waves), Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials, Optical pumping, Brillouin zone, Four-wave mixing, Optics, Light beam, Electrical and Electronic Engineering, Physical and Theoretical Chemistry, Reflection coefficient, business, Phase conjugation, Mixing (physics)
Abstract

It is shown that frequency detuning and phase mismatch effects can strongly effect the reflection coefficient of Brillouin enhanced four-wave mixing. Extremely large reflectivities ( R > 10 6 ) can be obtained if the intensities and frequency of the pump beams and the length of the interaction region all take on certain critical values. This theory accounts for the high reflectivity which has been reported by another author.

Published
1983
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38. Four wave mixing due to the optical kerr effect and Rayleigh-wing scattering

Author

A.M. Scott

Subjects
Physics, Kerr effect, Scattering, business.industry, Physics::Optics, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials, Brillouin zone, Four-wave mixing, symbols.namesake, Optics, Signal beam, Magneto-optic Kerr effect, symbols, Physics::Accelerator Physics, Electrical and Electronic Engineering, Physical and Theoretical Chemistry, Reflection coefficient, Rayleigh scattering, business
Abstract

The nearly degenerate four-wave mixing process is considered when the interaction arises through the Kerr nonlinearity and Rayleigh-wing scattering. It is found that the reflection coefficient depends on the product of the pump field strenghts, and that it progressively becomes smaller as the signal beam is detuned from the pump beam. This is in contrast with the electrostrictive case (i.e. the Brillouin type of interaction) where the reflectivity may become large at certain frequency detunings, and may depend on the ratio of the two pump fields, and the phase mismatch.

Published
1983
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