1. Biliary papillomatosis in three Caucasian patients in a Western centre
- Author
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Alastair L. Young, R. Brannan, Caroline S. Verbeke, A.D. White, K.R. Prasad, and A. Smith
- Subjects
Male ,medicine.medical_specialty ,Cholangitis ,Tertiary referral centre ,MEDLINE ,Biliary Papillomatosis ,Risk Assessment ,Sampling Studies ,Rare Diseases ,medicine ,Hepatectomy ,Humans ,Cholangiopancreatography, Endoscopic Retrograde ,Papilloma ,business.industry ,Biopsy, Needle ,Papillary Adenoma ,General Medicine ,Middle Aged ,Immunohistochemistry ,Magnetic Resonance Imaging ,Dermatology ,United Kingdom ,Liver Transplantation ,Surgery ,Survival Rate ,Biliary Tract Neoplasms ,Cell Transformation, Neoplastic ,Treatment Outcome ,Oncology ,Female ,Case note ,business ,Follow-Up Studies - Abstract
Introduction Biliary papillomatosis (BP) is a rare condition with a strong potential for malignant transformation and cases from Western centres are sparse. 1 We discuss the presentation, investigation and management of this condition in three Caucasian patients and present a review of the existing literature on BP. Patients and methods The case notes of three Caucasian patients with BP who presented to our tertiary referral centre were reviewed. Their case histories, investigations and managements are presented. A search of MEDLINE, PubMed and Cochrane databases was performed to review relevant literature around BP. Discussion BP is a rare condition characterised by multiple papillary adenomas involving the biliary tree which lead to recurrent attacks of cholangitis. It is a low-grade neoplasm with high malignant potential and should be regarded as a pre-malignant lesion.
- Published
- 2012