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9 results on '"A.B. Azaro Pedrazzoli"'

1. 918MO Molecular enrichment and outcomes based on ESCAT levels in metastatic salivary gland tumours (mSGT) patients (pts) treated in early clinical trials

Author

Margarita Alberola, A.B. Azaro Pedrazzoli, A. Hernando-Calvo, Maria Vieito, A. De Pablo, Sergi Benavente, Jordi Temprana-Salvador, Elena Garralda, Rodrigo Dienstmann, Jordi Giralt, Enriqueta Felip, Irene Brana, Vladimir Galvao, Susana Aguilar, R. Berché, Coro Bescos, G. Alonso Casal, Juan Lorente, M.A. Rezqallah Aron, and O. Saavedra Santa Gadea

Subjects
Clinical trial, Oncology, medicine.medical_specialty, medicine.anatomical_structure, Salivary gland, business.industry, Internal medicine, Medicine, Hematology, business
Published
2020
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2. 573P Efficacy of immunotherapy (IT) after prior immune checkpoint inhibitors (ICIs) exposure

Author

Rodrigo Dienstmann, M. Diez Garcia, Ignacio Matos, Irene Brana, Helena Verdaguer, O. Saavedra Santa Gadea, M. González, C. Ortiz Velez, Elena Garralda, I. Baraibar Argota, Vladimir Galvao, R. Berché, A. Hernando-Calvo, A. Valdivia, Maria Vieito, E. Muñoz Couselo, A. Callejo, G. Alonso Casal, J. Tabernero, and A.B. Azaro Pedrazzoli

Subjects
Oncology, business.industry, medicine.medical_treatment, Immune checkpoint inhibitors, Cancer research, medicine, Hematology, Immunotherapy, business
Published
2020
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3. 1068P Rescue chemotherapy (CT) after immune-oncology (IO) drugs in patients (pts) with refractory solid tumours: A propensity score (PS) matched cohort study

Author

J. Tabernero, Irene Brana, O. Saavedra Santa Gadea, A.B. Azaro Pedrazzoli, Elena Elez, Cristina Viaplana, G. Villacampa Javierre, T. Macarulla Mercade, F.J. Ros Montañá, Mafalda Oliveira, Ignacio Matos, M. Vieito Villar, Vladimir Galvao, A. Hernando-Calvo, Rodrigo Dienstmann, Joan Carles, G. Alonso Casal, E. Muñoz Couselo, Enriqueta Felip, and Elena Garralda

Subjects
Oncology, medicine.medical_specialty, Chemotherapy, business.industry, medicine.medical_treatment, Hematology, Matched cohort, Immune system, Refractory, Internal medicine, Propensity score matching, medicine, In patient, business
Published
2020
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4. 562P Target engagement and clinical safety of CB-103, a first-in-class small molecule inhibitor of the NOTCH transcription complex

Author

P. Pisa, E. Lopez Miranda, Michele Vigolo, Michael Bauer, Renata Ferrarotto, Anastasios Stathis, Karin Jorga, Rajwinder Lehal, Ana Vivancos, O. Schoenborn-Kellenberger, Laura Beni, Elena Garralda, J. Cortés, Paolo Nuciforo, Florian D. Vogl, A.B. Azaro Pedrazzoli, Dagmar Hess, J.M. Perez Garcia, M. Murone, and I. Colombo

Subjects
Class (computer programming), Oncology, business.industry, Transcription preinitiation complex, Target engagement, Medicine, Clinical safety, Hematology, Computational biology, business, Small molecule
Published
2020
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5. 3O VHIO immune gene-expression signature (VIGex) to enrich patient selection in immunotherapy phase I clinical trials

Author

A. Hernando, F.M. Mancuso, I. Braña, O. Saavedra, M. Vieito Villar, I. Gardeazabal Gonzalez, G. Alonso Casal, V. Galvao, A.B. Azaro Pedrazzoli, I. Matos Garcia, R. Berche, N.A. Wornham, C. Saura Manich, G. Argiles Martinez, E. Élez, E. Munoz Couselo, E. Felip, J. Tabernero, A. Vivancos, and E. Garralda

Subjects
Oncology, Hematology
Published
2020
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6. 380P Ten-year experience of the Vall d’Hebron Institute of Oncology early drug development unit (VHIO-UITM) treating patients (pts) with primary CNS tumours (pCNS)

Author

A.B. Azaro Pedrazzoli, F.J. Ros Montañá, G. Alonso Casal, V. Galvao de Aguiar, Elena Garralda, N. Saoudi Gonzalez, A. Hernando-Calvo, Francisco Martínez-Ricarte, Rodrigo Dienstmann, Joan Carles, A. Garcia-Alvarez, N. Ann Worham, M. C. González, Irene Brana, R. Berchel Barcelo, E. Martinez Saez, O. Saavedra Santa Gadea, J. Llavall Sanchez, M. Sole-Domenech, and M. Vieito Villar

Subjects
medicine.medical_specialty, Oncology, Drug development, business.industry, Internal medicine, medicine, Hematology, business
Published
2020
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7. 560P Safety and efficacy of Debio 1143, an antagonist of inhibitor of apoptosis proteins (IAPs), in combination with nivolumab in a phase Ib/II trial in patients (pts) failing prior PD-1/PD-L1 treatment

Author

T.C. Hernandez Guerrero, E. Roy, Carlos Gomez-Roca, I. Korakis, Eva Calvo, C. Riff, P. A. Cassier, A.B. Azaro Pedrazzoli, Kathrin Gollmer, Victor Moreno, D. Purcea, Sergio Szyldergemajn, M.J. de Miguel, and Caroline Even

Subjects
Oncology, biology, business.industry, PD-L1, Antagonist, biology.protein, Medicine, In patient, Hematology, Pharmacology, Nivolumab, Inhibitor of apoptosis, business
Published
2020
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8. 572P Limited efficacy of immunotherapy combination regimens in patients with unselected 'cold' tumours enrolled in early clinical trials

Author

A.B. Azaro Pedrazzoli, Irene Brana, M. Vieito Villar, G. Alonso Casal, Elena Garralda, O. Saavedra Santa Gadea, V. Galvao de Aguiar, T. Macarulla Mercade, Ignacio Matos, G. Argiles Martinez, Ana Oaknin, A. Pedrola, J. Tabernero, Rodrigo Dienstmann, Jaume Capdevila, R. Berché, I. Gardeazabal, A. Hernando-Calvo, Elena Elez, and Susana Cedres

Subjects
Clinical trial, medicine.medical_specialty, Oncology, business.industry, Internal medicine, medicine.medical_treatment, medicine, In patient, Hematology, Immunotherapy, business
Published
2020
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9. 1025MO First-in-human (FIH) phase I study of RO7122290 (RO), a novel FAP-targeted 4-1BB agonist, administered as single agent and in combination with atezolizumab (ATZ) to patients with advanced solid tumours

Author

Irene Moreno, Kristoffer Staal Rohrberg, T.C. Hernandez Guerrero, Alejo Rodriguez-Vida, Maria Martinez-Garcia, J. Tabernero, Evelyne Chesne, F.S. Lichtenegger, U. Sweere, Iben Spanggaard, Ernesto Guarin, I. Melero, A.B. Azaro Pedrazzoli, Victor Moreno, Oliver Krieter, Eva Calvo, Miguel F. Sanmamed, Eveline Nueesch, C. McIntyre, and Maurizio Ceppi

Subjects
Agonist, Oncology, medicine.drug_class, business.industry, Atezolizumab, medicine, Cancer research, Single agent, Hematology, First in human, business, Phase i study
Published
2020
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