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334 results on '"A. te Slaa"'

1. Circulating tumour cells to drive the use of neoadjuvant chemotherapy in patients with muscle-invasive bladder cancer

Author

Beije, N., de Kruijff, I.E., de Jong, J.J., Klaver, S.O., de Vries, P., Jacobs, R.A.L., Somford, D.M., te Slaa, E., van der Heijden, A.G., Alfred Witjes, J., Fossion, L.M.C.L., Boevé, E.R., van der Hoeven, J., van Melick, H.H.E., Wijburg, C.J., Bickerstaffe, H., Martens, J.W.M., de Wit, R., Kraan, J., Sleijfer, S., and Boormans, J.L.

Published
2022
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3. Outcomes in Octogenarians and the Effect of Comorbidities After Intact Abdominal Aortic Aneurysm Repair in the Netherlands: A Nationwide Cohort Study

Author

Van den Akker, P.J., Akkersdijk, G.J., Akkersdijk, G.P., Akkersdijk, W.L., van Andringa de Kempenaer, M.G., Arts, C.H., Avontuur, J.A., Bakker, O.J., Balm, R., Barendregt, W.B., Bekken, J.A., Bender, M.H., Bendermacher, B.L., van den Berg, M., Berger, P., Beuk, R.J., Blankensteijn, J.D., Bleker, R.J., Blok, J.J., Bode, A.S., Bodegom, M.E., van der Bogt, K.E., Boll, A.P., Booster, M.H., Borger van der Burg, B.L., de Borst, G.J., Bos- van Rossum, W.T., Bosma, J., Botman, J.M., Bouwman, L.H., Brehm, V., de Bruijn, M.T., de Bruin, J.L., Brummel, P., van Brussel, J.P., Buijk, S.E., Buijs, M.A., Buimer, M.G., Burger, D.H., Buscher, H.C., Cancrinus, E., Castenmiller, P.H., Cazander, G., Coester, A.M., Cuypers, P.H., Daemen, J.H., Dawson, I., Dierikx, J.E., Dijkstra, M.L., Diks, J., Dinkelman, M.K., Dirven, M., Dolmans, D.E., van Doorn, R.C., van Dortmont, L.M., Drouven, J.W., van der Eb, M.M., Eefting, D., van Eijck, G.J., Elshof, J.W., Elsman, B.H., van der Elst, A., van Engeland, M.I., van Eps, R.G., Faber, M.J., de Fijter, W.M., Fioole, B., Fokkema, T.M., Frans, F.A., Fritschy, W.M., Fung Kon Jin, P.H., Geelkerken, R.H., van Gent, W.B., Glade, G.J., Govaert, B., Groenendijk, R.P., de Groot, H.G., van den Haak, R.F., de Haan, E.F., Hajer, G.F., Hamming, J.F., van Hattum, E.S., Hazenberg, C.E., Hedeman Joosten, P.P., Helleman, J.N., van der Hem, L.G., Hendriks, J.M., van Herwaarden, J.A., Heyligers, J.M., Hinnen, J.W., Hissink, R.J., Ho, G.H., den Hoed, P.T., Hoedt, M.T., van Hoek, F., Hoencamp, R., Hoffmann, W.H., Hogendoorn, W., Hoksbergen, A.W., Hollander, E.J., Hommes, M., Hopmans, C.J., Huisman, L.C., Hulsebos, R.G., Huntjens, K.M., Idu, M.M., Jacobs, M.J., van der Jagt, M.F., Jansbeken, J.R., Janssen, R.J., Jiang, H.H., de Jong, S.C., Jongbloed-Winkel, T.A., Jongkind, V., Kapma, M.R., Keller, B.P., Khodadade Jahrome, A., Kievit, J.K., Klemm, P.L., Klinkert, P., Koedam, N.A., Koelemaij, M.J., Kolkert, J.L., Koning, G.G., Koning, O.H., Konings, R., Krasznai, A.G., Krol, R.M., Kropman, R.H., Kruse, R.R., van der Laan, L., van der Laan, M.J., van Laanen, J.H., van Lammeren, G.W., Lamprou, D.A., Lardenoye, J.H., Lauret, G.J., Leenders, B.J., Legemate, D.A., Leijdekkers, V.J., Lemson, M.S., Lensvelt, M.M., Lijkwan, M.A., Lind, R.C., van der Linden, F.T., Liqui Lung, P.F., Loos, M.J., Loubert, M.C., van de Luijtgaarden, K.M., Mahmoud, D.E., Manshanden, C.G., Mattens, E.C., Meerwaldt, R., Mees, B.M., von Meijenfeldt, G.C., Menting, T.P., Metz, R., Minnee, R.C., de Mol van Otterloo, J.C., Molegraaf, M.J., Montauban van Swijndregt, Y.C., Morak, M.J., van de Mortel, R.H., Mulder, W., Nagesser, S.K., Naves, C.C., Nederhoed, J.H., Nevenzel-Putters, A.M., de Nie, A.J., Nieuwenhuis, D.H., Nieuwenhuizen, J., van Nieuwenhuizen, R.C., Nio, D., Noyez, V.J., Oomen, A.P., Oranen, B.I., Oskam, J., Palamba, H.W., Peppelenbosch, A.G., van Petersen, A.S., Petri, B.J., Pierie, M.E., Ploeg, A.J., Pol, R.A., Ponfoort, E.D., Post, I.C., Poyck, P.P., Prent, A., ten Raa, S., Raymakers, J.T., Reichart, M., Reichmann, B.L., Reijnen, M.M., de Ridder, J.A., Rijbroek, A., van Rijn, M.J., de Roo, R.A., Rouwet, E.V., Saleem, B.R., Salemans, P.B., van Sambeek, M.R., Samyn, M.G., van ’t Sant, H.P., van Schaik, J., van Schaik, P.M., Scharn, D.M., Scheltinga, M.R., Schepers, A., Schlejen, P.M., Schlosser, F.J., Schol, F.P., Scholtes, V.P., Schouten, O., Schreve, M.A., Schurink, G.W., Sikkink, C.J., te Slaa, A., Smeets, H.J., Smeets, L., Smeets, R.R., de Smet, A.A., Smit, P.C., Smits, T.M., Snoeijs, M.G., Sondakh, A.O., Speijers, M.J., van der Steenhoven, T.J., van Sterkenburg, S.M., Stigter, D.A., Stokmans, R.A., Strating, R.P., Stultiëns, G.N., Sybrandy, J.E., Teijink, J.A., Telgenkamp, B.J., Teraa, M., Testroote, M.J., Tha-In, T., The, R.M., Thijsse, W.J., Thomassen, I., Tielliu, I.F., van Tongeren, R.B., Toorop, R.J., Tournoij, E., Truijers, M., Türkcan, K., Tutein Nolthenius, R.P., Ünlü, Ç., Vaes, R.H., Vafi, A.A., Vahl, A.C., Veen, E.J., Veger, H.T., Veldman, M.G., Velthuis, S., Verhagen, H.J., Verhoeven, B.A., Vermeulen, C.F., Vermeulen, E.G., Vierhout, B.P., van der Vijver-Coppen, R.J., Visser, M.J., van der Vliet, J.A., Vlijmen - van Keulen, C.J., Voorhoeve, R., van der Vorst, J.R., Vos, A.W., de Vos, B., Vos, C.G., Vos, G.A., Voute, M.T., Vriens, B.H., Vriens, P.W., de Vries, A.C., de Vries, D.K., de Vries, J.P., de Vries, M., van der Waal, C., Waasdorp, E.J., Wallis de Vries, B.M., van Walraven, L.A., van Wanroij, J.L., Warlé, M.C., van de Water, W., van Weel, V., van Well, A.M., Welten, G.M., Welten, R.J., Wever, J.J., Wiersema, A.M., Wikkeling, O.R., Willaert, W.I., Wille, J., Willems, M.C., Willigendael, E.M., Wilschut, E.D., Wisselink, W., Witte, M.E., Wittens, C.H., Wong, C.Y., Wouda, R., Yazar, O., Yeung, K.K., Zeebregts, C.J., van Zeeland, M.L., Alberga, Anna J., Karthaus, Eleonora G., van Zwet, Erik W., de Bruin, Jorg L., van Herwaarden, Joost A., Wever, Jan J., and Verhagen, Hence J.M.

Published
2021
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4. Nationwide Study to Predict Colonic Ischemia after Abdominal Aortic Aneurysm Repair in The Netherlands

Author

Van den Akker, L.H., Van den Akker, P.J., Akkersdijk, G.J., Akkersdijk, G.P., Akkersdijk, W.L., van Andringa de Kempenaer, M.G., Arts, C.H., Avontuur, J.A., Baal, J.G., Bakker, O.J., Balm, R., Barendregt, W.B., Bender, M.H., Bendermacher, B.L., van den Berg, M., Berger, P., Beuk, R.J., Blankensteijn, J.D., Bleker, R.J., Bockel, J.H., Bodegom, M.E., Bogt, K.E., Boll, A.P., Booster, M.H., Borger van der Burg, B.L., de Borst, G.J., Bos-van Rossum, W.T., Bosma, J., Botman, J.M., Bouwman, L.H., Breek, J.C., Brehm, V., Brinckman, M.J., van den Broek, T.H., Brom, H.L., de Bruijn, M.T., de Bruin, J.L., Brummel, P., van Brussel, J.P., Buijk, S.E., Buimer, M.G., Burger, D.H., Buscher, H.C., den Butter, G., Cancrinus, E., Castenmiller, P.H., Cazander, G., Coveliers, H.M., Cuypers, P.H., Daemen, J.H., Dawson, I., Derom, A.F., Dijkema, A.R., Diks, J., Dinkelman, M.K., Dirven, M., Dolmans, D.E., van Doorn, R.C., van Dortmont, L.M., van der Eb, M.M., Eefting, D., van Eijck, G.J., Elshof, J.W., Elsman, B.H., van der Elst, A., van Engeland, M.I., van Eps, R.G., Faber, M.J., de Fijter, W.M., Fioole, B., Fritschy, W.M., Geelkerken, R.H., van Gent, W.B., Glade, G.J., Govaert, B., Groenendijk, R.P., de Groot, H.G., van den Haak, R.F., de Haan, E.F., Hajer, G.F., Hamming, J.F., van Hattum, E.S., Hazenberg, C.E., Hedeman Joosten, P.P., Helleman, J.N., van der Hem, L.G., Hendriks, J.M., van Herwaarden, J.A., Heyligers, J.M., Hinnen, J.W., Hissink, R.J., Ho, G.H., den Hoed, P.T., Hoedt, M.T., van Hoek, F., Hoencamp, R., Hoffmann, W.H., Hoksbergen, A.W., Hollander, E.J., Huisman, L.C., Hulsebos, R.G., Huntjens, K.M., Idu, M.M., Jacobs, M.J., van der Jagt, M.F., Jansbeken, J.R., Janssen, R.J., Jiang, H.H., de Jong, S.C., Jongkind, V., Kapma, M.R., Keller, B.P., Khodadade Jahrome, A., Kievit, J.K., Klemm, P.L., Klinkert, P., Knippenberg, B., Koedam, N.A., Koelemaij, M.J., Kolkert, J.L., Koning, G.G., Koning, O.H., Krasznai, A.G., Krol, R.M., Kropman, R.H., Kruse, R.R., van der Laan, L., van der Laan, M.J., van Laanen, J.H., Lardenoye, J.H., Lawson, J.A., Legemate, D.A., Leijdekkers, V.J., Lemson, M.S., Lensvelt, M.M., Lijkwan, M.A., Lind, R.C., van der Linden, F.T., Liqui Lung, P.F., Loos, M.J., Loubert, M.C., Mahmoud, D.E., Manshanden, C.G., Mattens, E.C., Meerwaldt, R., Mees, B.M., Metz, R., Minnee, R.C., de Mol van Otterloo, J.C., Moll, F.L., Montauban van Swijndregt, Y.C., Morak, M.J., van de Mortel, R.H., Mulder, W., Nagesser, S.K., Naves, C.C., Nederhoed, J.H., Nevenzel-Putters, A.M., de Nie, A.J., Nieuwenhuis, D.H., Nieuwenhuizen, J., van Nieuwenhuizen, R.C., Nio, D., Oomen, A.P., Oranen, B.I., Oskam, J., Palamba, H.W., Peppelenbosch, A.G., van Petersen, A.S., Peterson, T.F., Petri, B.J., Pierie, M.E., Ploeg, A.J., Pol, R.A., Ponfoort, E.D., Poyck, P.P., Prent, A., ten Raa, S., Raymakers, J.T., Reichart, M., Reichmann, B.L., Reijnen, M.M., Rijbroek, A., van Rijn, M.J., de Roo, R.A., Rouwet, E.V., Rupert, C.G., Saleem, B.R., van Sambeek, M.R., Samyn, M.G., van’t Sant, H.P., van Schaik, J., van Schaik, P.M., Scharn, D.M., Scheltinga, M.R., Schepers, A., Schlejen, P.M., Schlosser, F.J., Schol, F.P., Schouten, O., Schreinemacher, M.H., Schreve, M.A., Schurink, G.W., Sikkink, C.J., Siroen, M.P., te Slaa, A., Smeets, H.J., Smeets, L., de Smet, A.A., de Smit, P., Smit, P.C., Smits, T.M., Snoeijs, M.G., Sondakh, A.O., van der Steenhoven, T.J., van Sterkenburg, S.M., Stigter, D.A., Stigter, H., Strating, R.P., Stultiëns, G.N., Sybrandy, J.E., Teijink, J.A., Telgenkamp, B.J., Testroote, M.J., The, R.M., Thijsse, W.J., Tielliu, I.F., van Tongeren, R.B., Toorop, R.J., Tordoir, J.H., Tournoij, E., Truijers, M., Türkcan, K., Tutein Nolthenius, R.P., Ünlü, Ç., Vafi, A.A., Vahl, A.C., Veen, E.J., Veger, H.T., Veldman, M.G., Verhagen, H.J., Verhoeven, B.A., Vermeulen, C.F., Vermeulen, E.G., Vierhout, B.P., Visser, M.J., van der Vliet, J.A., Vlijmen-van Keulen, C.J., Voesten, H.G., Voorhoeve, R., Vos, A.W., de Vos, B., Vos, G.A., Vriens, B.H., Vriens, P.W., de Vries, A.C., de Vries, J.P., de Vries, M., van der Waal, C., Waasdorp, E.J., Wallis de Vries, B.M., van Walraven, L.A., van Wanroij, J.L., Warlé, M.C., van Weel, V., van Well, A.M., Welten, G.M., Welten, R.J., Wever, J.J., Wiersema, A.M., Wikkeling, O.R., Willaert, W.I., Wille, J., Willems, M.C., Willigendael, E.M., Wisselink, W., Witte, M.E., Wittens, C.H., Wolf-de Jonge, I.C., Yazar, O., Zeebregts, C.J., van Zeeland, M.L., Willemsen, Saskia Irene, ten Berge, Martijn Geert, Statius van Eps, Randolph George, Veger, Hugo Thomas Christian, van Overhagen, Hans, van Dijk, Lukas Carolus, Putter, Hein, and Wever, Jan Jacob

Published
2021
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5. "Your brain can't wait": perspectives of children and adolescents with acquired brain injury and their parents on physical rehabilitation during the subacute phase.

Author

Gmelig Meyling, Christiaan, Verschuren, Olaf, Rentinck, Ingrid C. M., van Driel, Dimara, te Slaa, Esmée, Engelbert, Raoul H., and Gorter, Jan Willem

Subjects
REHABILITATION for brain injury patients, PHYSICAL therapy, THERAPEUTICS, RESEARCH funding, QUALITATIVE research, INTERVIEWING, PARENT attitudes, PARENTING, ATTITUDE (Psychology), SUBACUTE care, THEMATIC analysis, RESEARCH methodology, COMMUNICATION, CONVALESCENCE, RESEARCH, DATA analysis software, HOPE, ADOLESCENCE, CHILDREN
Abstract

Purpose: Physical interventions during subacute rehabilitation have potential to improve functional recovery. This study explored the perspectives of children and adolescents with acquired brain injury (ABI) and their parents with respect to physical rehabilitation during the subacute phase. Methods: Thirteen children and adolescents with ABI and their parents were included and interviewed using semi-structured interviews. Interview transcripts were analysed using inductive thematic analysis approach. Results: Six themes were identified: 1) beliefs of physical rehabilitation, 2) content of physical rehabilitation, 3) tailored care, 4) impact of context, 5) communication and 6) transition. The importance of intensive physical practice was widely supported. The positive can-do mentality was emphasised to create an atmosphere of hope, meaning that every effort would be made to achieve maximum recovery. Intensive involvement of parents is considered essential during subacute rehabilitation including an open and mutual dialogue about the focus of rehabilitation, therapy goals and future participation in their own environment. Conclusions: Our findings highlight the need for an intensive rehabilitation approach, tailored to the individual's needs. The perspectives of children and adolescents and their parents in our study contribute to a better understanding of factors that are important for optimal recovery through physical rehabilitation during the subacute phase. IMPLICATIONS FOR REHABILITATION: Children with acquired brain injury and their parents indicate the potential and thus the importance of intensive physical practice to enhance optimal recovery. Involvement of parents and the potential of their continuous presence during subacute rehabilitation may have a positive impact on the effect of rehabilitation efforts. The positive can-do mentality of rehabilitation professionals creates an atmosphere of hope and is an important requisite to achieve maximum recovery. Open dialogue between clinicians and the family is warranted about the focus of interventions. [ABSTRACT FROM AUTHOR]

Published
2024
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6. Patients with a Ruptured Abdominal Aortic Aneurysm Are Better Informed in Hospitals with an “EVAR-preferred” Strategy: An Instrumental Variable Analysis of the Dutch Surgical Aneurysm Audit

Author

Van den Akker, P.J., Akkersdijk, G.J., Akkersdijk, G.P., Akkersdijk, W.L., van Andringa de Kempenaer, M.G., Arts, C.H., Avontuur, J.A., Bakker, O.J., Balm, R., Barendregt, W.B., Bekken, J.A., Bender, M.H., Bendermacher, B.L., van den Berg, M., Berger, P., Beuk, R.J., Blankensteijn, J.D., Bleker, R.J., Blok, J.J., Bode, A.S., Bodegom, M.E., van der Bogt, K.E., Boll, A.P., Booster, M.H., Borger van der Burg, B.L., de Borst, G.J., Bos- van Rossum, W.T., Bosma, J., Botman, J.M., Bouwman, L.H., Brehm, V., de Bruijn, M.T., de Bruin, J.L., Brummel, P., van Brussel, J.P., Buijk, S.E., Buijs, M.A., Buimer, M.G., Burger, D.H., Buscher, H.C., Cancrinus, E., Castenmiller, P.H., Cazander, G., Coester, A.M., Cuypers, P.H., Daemen, J.H., Dawson, I., Dierikx, J.E., Dijkstra, M.L., Diks, J., Dinkelman, M.K., Dirven, M., Dolmans, D.E., van Doorn, R.C., van Dortmont, L.M., Drouven, J.W., van der Eb, M.M., Eefting, D., van Eijck, G.J., Elshof, J.W., Elsman, B.H., van der Elst, A., van Engeland, M.I., van Eps, R.G., Faber, M.J., de Fijter, W.M., Fioole, B., Fokkema, T.M., Frans, F.A., Fritschy, W.M., Fung Kon Jin, P.H., Geelkerken, R.H., van Gent, W.B., Glade, G.J., Govaert, B., Groenendijk, R.P., de Groot, H.G., van den Haak, R.F., de Haan, E.F., Hajer, G.F., Hamming, J.F., van Hattum, E.S., Hazenberg, C.E., Hedeman Joosten, P.P., Helleman, J.N., van der Hem, L.G., Hendriks, J.M., van Herwaarden, J.A., Heyligers, J.M., Hinnen, J.W., Hissink, R.J., Ho, G.H., den Hoed, P.T., Hoedt, M.T., van Hoek, F., Hoencamp, R., Hoffmann, W.H., Hogendoorn, W., Hoksbergen, A.W., Hollander, E.J., Hommes, M., Hopmans, C.J., Huisman, L.C., Hulsebos, R.G., Huntjens, K.M., Idu, M.M., Jacobs, M.J., van der Jagt, M.F., Jansbeken, J.R., Janssen, R.J., Jiang, H.H., de Jong, S.C., Jongbloed-Winkel, T.A., Jongkind, V., Kapma, M.R., Keller, B.P., Khodadade Jahrome, A., Kievit, J.K., Klemm, P.L., Klinkert, P., Koedam, N.A., Koelemaij, M.J., Kolkert, J.L., Koning, G.G., Koning, O.H., Konings, R., Krasznai, A.G., Krol, R.M., Kropman, R.H., Kruse, R.R., van der Laan, L., van der Laan, M.J., van Laanen, J.H., van Lammeren, G.W., Lamprou, D.A., Lardenoye, J.H., Lauret, G.J., Leenders, B.J., Legemate, D.A., Leijdekkers, V.J., Lemson, M.S., Lensvelt, M.M., Lijkwan, M.A., Lind, R.C., van der Linden, F.T., Liqui Lung, P.F., Loos, M.J., Loubert, M.C., van de Luijtgaarden, K.M., Mahmoud, D.E., Manshanden, C.G., Mattens, E.C., Meerwaldt, R., Mees, B.M., von Meijenfeldt, G.C., Menting, T.P., Metz, R., Minnee, R.C., de Mol van Otterloo, J.C., Molegraaf, M.J., Montauban van Swijndregt, Y.C., Morak, M.J., van de Mortel, R.H., Mulder, W., Nagesser, S.K., Naves, C.C., Nederhoed, J.H., Nevenzel-Putters, A.M., de Nie, A.J., Nieuwenhuis, D.H., Nieuwenhuizen, J., van Nieuwenhuizen, R.C., Nio, D., Noyez, V.J., Oomen, A.P., Oranen, B.I., Oskam, J., Palamba, H.W., Peppelenbosch, A.G., van Petersen, A.S., Petri, B.J., Pierie, M.E., Ploeg, A.J., Pol, R.A., Ponfoort, E.D., Post, I.C., Poyck, P.P., Prent, A., ten Raa, S., Raymakers, J.T., Reichart, M., Reichmann, B.L., Reijnen, M.M., de Ridder, J.A., Rijbroek, A., van Rijn, M.J., de Roo, R.A., Rouwet, E.V., Saleem, B.R., Salemans, P.B., van Sambeek, M.R., Samyn, M.G., van ’t Sant, H.P., van Schaik, J., van Schaik, P.M., Scharn, D.M., Scheltinga, M.R., Schepers, A., Schlejen, P.M., Schlosser, F.J., Schol, F.P., Scholtes, V.P., Schouten, O., Schreve, M.A., Schurink, G.W., Sikkink, C.J., te Slaa, A., Smeets, H.J., Smeets, L., Smeets, R.R., de Smet, A.A., Smit, P.C., Smits, T.M., Snoeijs, M.G., Sondakh, A.O., Speijers, M.J., van der Steenhoven, T.J., van Sterkenburg, S.M., Stigter, D.A., Stokmans, R.A., Strating, R.P., Stultiëns, G.N., Sybrandy, J.E., Teijink, J.A., Telgenkamp, B.J., Teraa, M., Testroote, M.J., Tha-In, T., The, R.M., Thijsse, W.J., Thomassen, I., Tielliu, I.F., van Tongeren, R.B., Toorop, R.J., Tournoij, E., Truijers, M., Türkcan, K., Tutein Nolthenius, R.P., Ünlü, Ç., Vaes, R.H., Vafi, A.A., Vahl, A.C., Veen, E.J., Veger, H.T., Veldman, M.G., Velthuis, S., Verhagen, H.J., Verhoeven, B.A., Vermeulen, C.F., Vermeulen, E.G., Vierhout, B.P., van der Vijver-Coppen, R.J., Visser, M.J., van der Vliet, J.A., Vlijmen - van Keulen, C.J., Voorhoeve, R., van der Vorst, J.R., Vos, A.W., de Vos, B., Vos, C.G., Vos, G.A., Voute, M.T., Vriens, B.H., Vriens, P.W., de Vries, A.C., de Vries, D.K., de Vries, J.P., de Vries, M., van der Waal, C., Waasdorp, E.J., Wallis de Vries, B.M., van Walraven, L.A., van Wanroij, J.L., Warlé, M.C., van de Water, W., van Weel, V., van Well, A.M., Welten, G.M., Welten, R.J., Wever, J.J., Wiersema, A.M., Wikkeling, O.R., Willaert, W.I., Wille, J., Willems, M.C., Willigendael, E.M., Wilschut, E.D., Wisselink, W., Witte, M.E., Wittens, C.H., Wong, C.Y., Wouda, R., Yazar, O., Yeung, K.K., Zeebregts, C.J., van Zeeland, M.L., Karthaus, Eleonora G., Lijftogt, Niki, Vahl, Anco, van der Willik, Esmee M., Amodio, Sonia, van Zwet, Erik W., and Hamming, Jaap F.

Published
2020
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7. Treatment of High-grade Non–muscle-invasive Bladder Carcinoma by Standard Number and Dose of BCG Instillations Versus Reduced Number and Standard Dose of BCG Instillations: Results of the European Association of Urology Research Foundation Randomised Phase III Clinical Trial “NIMBUS”

Author

Horstmann, Jörg, Machtens, Stefan, Mumperow, Eberhard, Ghazal, Andreas Al, Pulte, Thomas, Stephan-Odenthal, Michael, Gakis, Georgios, Kramer, Mario, Grimm, Marc-Oliver, Zaak, Dirk, Schmitz-Dräger, Bernd, Schreier, Holger, Lehmann, Jan, Werner, Torsten, Klier, Jörg, Marin, Jan, Rulf, Wolfgang, Hellmis, Eva, Schneider, Andreas, Spiegelhalder, Wirth, Manfred, Klotz, Theodor, Suttmann, Henrik, Siebels, Michael, Rodemer, Gerd, Rudolph, Robert, Zillmann, Roger, de Bruin, M., Bos, S., van Moorselaar, R., de Reijke, T, Boormans, J., Wijsman, B., van Melick, H.H.E., van Boven, E., Meijer, R.P., van der Heijden, A.G., Vergunst, H., te Slaa, E., Leliveld-Kors, A.M., Colombel, Marc, Ruffion, Alain, Pfister, Christian, Roupret, Morgan, Irani, Jacques, Stoica, Gabriel, Van Bruwaene, Siska, Ameye, Filip, Arentsen, Harm, Joniau, Steven, Beardo, Pastora, van der Heijden, Antoine G., Muilwijk, Tim, Martínez-Piñeiro, Luis, Babjuk, Marko M., Türkeri, Levent N., Palou, Joan, Patel, Anup, Bjartell, Anders S., Caris, Christien, Schipper, Raymond G., and Witjes, Wim P.J.

Published
2020
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8. A Composite Measure for Quality of Care in Patients with Symptomatic Carotid Stenosis Using Textbook Outcome

Author

Van den Akker, P.J., Akkersdijk, G.J., Akkersdijk, G.P., Akkersdijk, W.L., van Andringa de Kempenaer, M.G., Arts, C.H., Avontuur, J.A., Bakker, O.J., Balm, R., Barendregt, W.B., Bekken, J.A., Bender, M.H., Bendermacher, B.L., van den Berg, M., Berger, P., Beuk, R.J., Blankensteijn, J.D., Bleker, R.J., Blok, J.J., Bode, A.S., Bodegom, M.E., van der Bogt, K.E., Boll, A.P., Booster, M.H., Borger van der Burg, B.L., de Borst, G.J., Bos-van Rossum, W.T., Bosma, J., Botman, J.M., Bouwman, L.H., Brehm, V., de Bruijn, M.T., de Bruin, J.L., Brummel, P., van Brussel, J.P., Buijk, S.E., Buijs, M.A., Buimer, M.G., Burger, D.H., Buscher, H.C., Cancrinus, E., Castenmiller, P.H., Cazander, G., Coester, A.M., Cuypers, P.H., Daemen, J.H., Dawson, I., Dierikx, J.E., Dijkstra, M.L., Diks, J., Dinkelman, M.K., Dirven, M., Dolmans, D.E., van Doorn, R.C., van Dortmont, L.M., Drouven, J.W., van der Eb, M.M., Eefting, D., van Eijck, G.J., Elshof, J.W., Elsman, B.H., van der Elst, A., van Engeland, M.I., van Eps, R.G., Faber, M.J., de Fijter, W.M., Fioole, B., Fokkema, T.M., Frans, F.A., Fritschy, W.M., Fung Kon Jin, P.H., Geelkerken, R.H., van Gent, W.B., Glade, G.J., Govaert, B., Groenendijk, R.P., de Groot, H.G., van den Haak, R.F., de Haan, E.F., Hajer, G.F., Hamming, J.F., van Hattum, E.S., Hazenberg, C.E., Hedeman Joosten, P.P., Helleman, J.N., van der Hem, L.G., Hendriks, J.M., van Herwaarden, J.A., Heyligers, J.M., Hinnen, J.W., Hissink, R.J., Ho, G.H., den Hoed, P.T., Hoedt, M.T., van Hoek, F., Hoencamp, R., Hoffmann, W.H., Hogendoorn, W., Hoksbergen, A.W., Hollander, E.J., Hommes, M., Hopmans, C.J., Huisman, L.C., Hulsebos, R.G., Huntjens, K.M., Idu, M.M., Jacobs, M.J., van der Jagt, M.F., Jansbeken, J.R., Janssen, R.J., Jiang, H.H., de Jong, S.C., Jongbloed-Winkel, T.A., Jongkind, V., Kapma, M.R., Keller, B.P., Khodadade Jahrome, A., Kievit, J.K., Klemm, P.L., Klinkert, P., Koedam, N.A., Koelemaij, M.J., Kolkert, J.L., Koning, G.G., Koning, O.H., Konings, R., Krasznai, A.G., Krol, R.M., Kropman, R.H., Kruse, R.R., van der Laan, L., van der Laan, M.J., van Laanen, J.H., van Lammeren, G.W., Lamprou, D.A., Lardenoye, J.H., Lauret, G.J., Leenders, B.J., Legemate, D.A., Leijdekkers, V.J., Lemson, M.S., Lensvelt, M.M., Lijkwan, M.A., Lind, R.C., van der Linden, F.T., Liqui Lung, P.F., Loos, M.J., Loubert, M.C., van de Luijtgaarden, K.M., Mahmoud, D.E., Manshanden, C.G., Mattens, E.C., Meerwaldt, R., Mees, B.M., von Meijenfeldt, G.C., Menting, T.P., Metz, R., Minnee, R.C., de Mol van Otterloo, J.C., Molegraaf, M.J., Montauban van Swijndregt, Y.C., Morak, M.J., van de Mortel, R.H., Mulder, W., Nagesser, S.K., Naves, C.C., Nederhoed, J.H., Nevenzel-Putters, A.M., de Nie, A.J., Nieuwenhuis, D.H., Nieuwenhuizen, J., van Nieuwenhuizen, R.C., Nio, D., Noyez, V.J., Oomen, A.P., Oranen, B.I., Oskam, J., Palamba, H.W., Peppelenbosch, A.G., van Petersen, A.S., Petri, B.J., Pierie, M.E., Ploeg, A.J., Pol, R.A., Ponfoort, E.D., Post, I.C., Poyck, P.P., Prent, A., ten Raa, S., Raymakers, J.T., Reichart, M., Reichmann, B.L., Reijnen, M.M., de Ridder, J.A., Rijbroek, A., van Rijn, M.J., de Roo, R.A., Rouwet, E.V., Saleem, B.R., Salemans, P.B., van Sambeek, M.R., Samyn, M.G., van ’t Sant, H.P., van Schaik, J., van Schaik, P.M., Scharn, D.M., Scheltinga, M.R., Schepers, A., Schlejen, P.M., Schlosser, F.J., Schol, F.P., Scholtes, V.P., Schouten, O., Schreve, M.A., Schurink, G.W., Sikkink, C.J., te Slaa, A., Smeets, H.J., Smeets, L., Smeets, R.R., de Smet, A.A., Smit, P.C., Smits, T.M., Snoeijs, M.G., Sondakh, A.O., Speijers, M.J., van der Steenhoven, T.J., van Sterkenburg, S.M., Stigter, D.A., Stokmans, R.A., Strating, R.P., Stultiëns, G.N., Sybrandy, J.E., Teijink, J.A., Telgenkamp, B.J., Teraa, M., Testroote, M.J., Tha-In, T., The, R.M., Thijsse, W.J., Thomassen, I., Tielliu, I.F., van Tongeren, R.B., Toorop, R.J., Tournoij, E., Truijers, M., Türkcan, K., Tutein Nolthenius, R.P., Ünlü, Ç., Vaes, R.H., Vafi, A.A., Vahl, A.C., Veen, E.J., Veger, H.T., Veldman, M.G., Velthuis, S., Verhagen, H.J., Verhoeven, B.A., Vermeulen, C.F., Vermeulen, E.G., Vierhout, B.P., van der Vijver-Coppen, R.J., Visser, M.J., van der Vliet, J.A., Vlijmen - van Keulen, C.J., Voorhoeve, R., van der Vorst, J.R., Vos, A.W., de Vos, B., Vos, C.G., Vos, G.A., Voute, M.T., Vriens, B.H., Vriens, P.W., de Vries, A.C., de Vries, D.K., de Vries, J.P., de Vries, M., van der Waal, C., Waasdorp, E.J., Wallis de Vries, B.M., van Walraven, L.A., van Wanroij, J.L., Warlé, M.C., van de Water, W., van Weel, V., van Well, A.M., Welten, G.M., Welten, R.J., Wever, J.J., Wiersema, A.M., Wikkeling, O.R., Willaert, W.I., Wille, J., Willems, M.C., Willigendael, E.M., Wilschut, E.D., Wisselink, W., Witte, M.E., Wittens, C.H., Wong, C.Y., Wouda, R., Yazar, O., Yeung, K.K., Zeebregts, C.J., van Zeeland, M.L., Kuhrij, Laurien S., Karthaus, Eleonora G., Vahl, Anco C., Willems, Martine C.M., Elshof, Jan W., and de Borst, Gert J.

Published
2020
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9. National Numbers of Secondary Aortic Reinterventions after Primary Abdominal Aortic Aneurysm Surgery from the Dutch Surgical Aneurysm Audit

Author

Van den Akker, P.J., Akkersdijk, G.J., Akkersdijk, G.P., Akkersdijk, W.L., van Andringa de Kempenaer, M.G., Arts, C.H., Avontuur, J.A., Bakker, O.J., Balm, R., Barendregt, W.B., Bekken, J.A., Bender, M.H., Bendermacher, B.L., van den Berg, M., Berger, P., Beuk, R.J., Blankensteijn, J.D., Bleker, R.J., Blok, J.J., Bode, A.S., Bodegom, M.E., van der Bogt, K.E., Boll, A.P., Booster, M.H., Borger van der Burg, B.L., de Borst, G.J., Bos-van Rossum, W.T., Bosma, J., Botman, J.M., Bouwman, L.H., Brehm, V., de Bruijn, M.T., de Bruin, J.L., Brummel, P., van Brussel, J.P., Buijk, S.E., Buijs, M.A., Buimer, M.G., Burger, D.H., Buscher, H.C., Cancrinus, E., Castenmiller, P.H., Cazander, G., Coester, A.M., Cuypers, P.H., Daemen, J.H., Dawson, I., Dierikx, J.E., Dijkstra, M.L., Diks, J., Dinkelman, M.K., Dirven, M., Dolmans, D.E., van Doorn, R.C., van Dortmont, L.M., Drouven, J.W., van der Eb, M.M., Eefting, D., van Eijck, G.J., Elshof, J.W., Elsman, B.H., van der Elst, A., van Engeland, M.I., van Eps, R.G., Faber, M.J., de Fijter, W.M., Fioole, B., Fokkema, T.M., Frans, F.A., Fritschy, W.M., Fung Kon Jin, P.H., Geelkerken, R.H., van Gent, W.B., Glade, G.J., Govaert, B., Groenendijk, R.P., de Groot, H.G., van den Haak, R.F., de Haan, E.F., Hajer, G.F., Hamming, J.F., van Hattum, E.S., Hazenberg, C.E., Hedeman Joosten, P.P., Helleman, J.N., van der Hem, L.G., Hendriks, J.M., van Herwaarden, J.A., Heyligers, J.M., Hinnen, J.W., Hissink, R.J., Ho, G.H., den Hoed, P.T., Hoedt, M.T., van Hoek, F., Hoencamp, R., Hoffmann, W.H., Hogendoorn, W., Hoksbergen, A.W., Hollander, E.J., Hommes, M., Hopmans, C.J., Huisman, L.C., Hulsebos, R.G., Huntjens, K.M., Idu, M.M., Jacobs, M.J., van der Jagt, M.F., Jansbeken, J.R., Janssen, R.J., Jiang, H.H., de Jong, S.C., Jongbloed-Winkel, T.A., Jongkind, V., Kapma, M.R., Keller, B.P., Khodadade Jahrome, A., Kievit, J.K., Klemm, P.L., Klinkert, P., Koedam, N.A., Koelemaij, M.J., Kolkert, J.L., Koning, G.G., Koning, O.H., Konings, R., Krasznai, A.G., Krol, R.M., Kropman, R.H., Kruse, R.R., van der Laan, L., van der Laan, M.J., van Laanen, J.H., van Lammeren, G.W., Lamprou, D.A., Lardenoye, J.H., Lauret, G.J., Leenders, B.J., Legemate, D.A., Leijdekkers, V.J., Lemson, M.S., Lensvelt, M.M., Lijkwan, M.A., Lind, R.C., van der Linden, F.T., Liqui Lung, P.F., Loos, M.J., Loubert, M.C., van de Luijtgaarden, K.M., Mahmoud, D.E., Manshanden, C.G., Mattens, E.C., Meerwaldt, R., Mees, B.M., von Meijenfeldt, G.C., Menting, T.P., Metz, R., Minnee, R.C., de Mol van Otterloo, J.C., Molegraaf, M.J., Montauban van Swijndregt, Y.C., Morak, M.J., van de Mortel, R.H., Mulder, W., Nagesser, S.K., Naves, C.C., Nederhoed, J.H., Nevenzel-Putters, A.M., de Nie, A.J., Nieuwenhuis, D.H., Nieuwenhuizen, J., van Nieuwenhuizen, R.C., Nio, D., Noyez, V.J., Oomen, A.P., Oranen, B.I., Oskam, J., Palamba, H.W., Peppelenbosch, A.G., van Petersen, A.S., Petri, B.J., Pierie, M.E., Ploeg, A.J., Pol, R.A., Ponfoort, E.D., Post, I.C., Poyck, P.P., Prent, A., ten Raa, S., Raymakers, J.T., Reichart, M., Reichmann, B.L., Reijnen, M.M., de Ridder, J.A., Rijbroek, A., van Rijn, M.J., de Roo, R.A., Rouwet, E.V., Saleem, B.R., Salemans, P.B., van Sambeek, M.R., Samyn, M.G., van't Sant, H.P., van Schaik, J., van Schaik, P.M., Scharn, D.M., Scheltinga, M.R., Schepers, A., Schlejen, P.M., Schlosser, F.J., Schol, F.P., Scholtes, V.P., Schouten, O., Schreve, M.A., Schurink, G.W., Sikkink, C.J., te Slaa, A., Smeets, H.J., Smeets, L., Smeets, R.R., de Smet, A.A., Smit, P.C., Smits, T.M., Snoeijs, M.G., Sondakh, A.O., Speijers, M.J., van der Steenhoven, T.J., van Sterkenburg, S.M., Stigter, D.A., Stokmans, R.A., Strating, R.P., Stultiëns, G.N., Sybrandy, J.E., Teijink, J.A., Telgenkamp, B.J., Teraa, M., Testroote, M.J., Tha-In, T., The, R.M., Thijsse, W.J., Thomassen, I., Tielliu, I.F., van Tongeren, R.B., Toorop, R.J., Tournoij, E., Truijers, M., Türkcan, K., Tutein Nolthenius, R.P., Ünlü, Ç., Vaes, R.H., Vafi, A.A., Vahl, A.C., Veen, E.J., Veger, H.T., Veldman, M.G., Velthuis, S., Verhagen, H.J., Verhoeven, B.A., Vermeulen, C.F., Vermeulen, E.G., Vierhout, B.P., van der Vijver-Coppen, R.J., Visser, M.J., van der Vliet, J.A., Vlijmen-van Keulen, C.J., Voorhoeve, R., van der Vorst, J.R., Vos, A.W., de Vos, B., Vos, C.G., Vos, G.A., Voute, M.T., Vriens, B.H., Vriens, P.W., de Vries, A.C., de Vries, D.K., de Vries, J.P., de Vries, M., van der Waal, C., Waasdorp, E.J., de Vries, W., van Walraven, L.A., van Wanroij, J.L., Warlé, M.C., van de Water, W., van Weel, V., van Well, A.M., Welten, G.M., Welten, R.J., Wever, J.J., Wiersema, A.M., Wikkeling, O.R., Willaert, W.I., Wille, J., Willems, M.C., Willigendael, E.M., Wilschut, E.D., Wisselink, W., Witte, M.E., Wittens, C.H., Wong, C.Y., Wouda, R., Yazar, O., Yeung, K.K., Zeebregts, C.J., van Zeeland, M.L., Karthaus, Eleonora G., Vahl, Anco, Elsman, Bernard H.P., Wouters, Michel W.J.M., de Borst, Gert J., and Hamming, Jaap F.

Published
2020
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10. Editor's Choice – Nationwide Analysis of Patients Undergoing Iliac Artery Aneurysm Repair in the Netherlands

Author

Jalalzadeh, Hamid, Indrakusuma, Reza, Koelemay, Mark J.W., Balm, Ron, Van den Akker, L.H., Van den Akker, P.J., Akkersdijk, G.J., Akkersdijk, G.P., Akkersdijk, W.L., van Andringa de Kempenaer, M.G., Arts, C.H., Avontuur, J.A., Baal, J.G., Bakker, O.J., Balm, R., Barendregt, W.B., Bender, M.H., Bendermacher, B.L., van den Berg, M., Berger, P., Beuk, R.J., Blankensteijn, J.D., Bleker, R.J., Bockel, J.H., Bodegom, M.E., Bogt, K.E., Boll, A.P., Booster, M.H., Borger van der Burg, B.L., de Borst, G.J., Bos-van Rossum, W.T., Bosma, J., Botman, J.M., Bouwman, L.H., Breek, J.C., Brehm, V., Brinckman, M.J., van den Broek, T.H., Brom, H.L., de Bruijn, M.T., de Bruin, J.L., Brummel, P., van Brussel, J.P., Buijk, S.E., Buimer, M.G., Burger, D.H., Buscher, H.C., den Butter, G., Cancrinus, E., Castenmiller, P.H., Cazander, G., Coveliers, H.M., Cuypers, P.H., Daemen, J.H., Dawson, I., Derom, A.F., Dijkema, A.R., Diks, J., Dinkelman, M.K., Dirven, M., Dolmans, D.E., van Doorn, R.C., van Dortmont, L.M., van der Eb, M.M., Eefting, D., van Eijck, G.J., Elshof, J.W., Elsman, B.H., van der Elst, A., van Engeland, M.I., van Eps, R.G., Faber, M.J., de Fijter, W.M., Fioole, B., Fritschy, W.M., Geelkerken, R.H., van Gent, W.B., Glade, G.J., Govaert, B., Groenendijk, R.P., de Groot, H.G., van den Haak, R.F., de Haan, E.F., Hajer, G.F., Hamming, J.F., van Hattum, E.S., Hazenberg, C.E., Hedeman Joosten, P.P., Helleman, J.N., van der Hem, L.G., Hendriks, J.M., van Herwaarden, J.A., Heyligers, J.M., Hinnen, J.W., Hissink, R.J., Ho, G.H., den Hoed, P.T., Hoedt, M.T., van Hoek, F., Hoencamp, R., Hoffmann, W.H., Hoksbergen, A.W., Hollander, E.J., Huisman, L.C., Hulsebos, R.G., Huntjens, K.M., Idu, M.M., Jacobs, M.J., van der Jagt, M.F., Jansbeken, J.R., Janssen, R.J., Jiang, H.H., de Jong, S.C., Jongkind, V., Kapma, M.R., Keller, B.P., Khodadade Jahrome, A., Kievit, J.K., Klemm, P.L., Klinkert, P., Knippenberg, B., Koedam, N.A., Koelemay, M.J., Kolkert, J.L., Koning, G.G., Koning, O.H., Krasznai, A.G., Krol, R.M., Kropman, R.H., Kruse, R.R., van der Laan, L., van der Laan, M.J., van Laanen, J.H., Lardenoye, J.H., Lawson, J.A., Legemate, D.A., Leijdekkers, V.J., Lemson, M.S., Lensvelt, M.M., Lijkwan, M.A., Lind, R.C., van der Linden, F.T., Liqui Lung, P.F., Loos, M.J., Loubert, M.C., Mahmoud, D.E., Manshanden, C.G., Mattens, E.C., Meerwaldt, R., Mees, B.M., Metz, R., Minnee, R.C., de Mol van Otterloo, J.C., Moll, F.L., Montauban van Swijndregt, Y.C., Morak, M.J., van de Mortel, R.H., Mulder, W., Nagesser, S.K., Naves, C.C., Nederhoed, J.H., Nevenzel-Putters, A.M., de Nie, A.J., Nieuwenhuis, D.H., Nieuwenhuizen, J., van Nieuwenhuizen, R.C., Nio, D., Oomen, A.P., Oranen, B.I., Oskam, J., Palamba, H.W., Peppelenbosch, A.G., van Petersen, A.S., Peterson, T.F., Petri, B.J., Pierie, M.E., Ploeg, A.J., Pol, R.A., Ponfoort, E.D., Poyck, P.P., Prent, A., ten Raa, S., Raymakers, J.T., Reichart, M., Reichmann, B.L., Reijnen, M.M., Rijbroek, A., van Rijn, M.J., de Roo, R.A., Rouwet, E.V., Rupert, C.G., Saleem, B.R., van Sambeek, M.R., Samyn, M.G., van ’t Sant, H.P., van Schaik, J., van Schaik, P.M., Scharn, D.M., Scheltinga, M.R., Schepers, A., Schlejen, P.M., Schlosser, F.J., Schol, F.P., Schouten, O., Schreinemacher, M.H., Schreve, M.A., Schurink, G.W., Sikkink, C.J., Siroen, M.P., te Slaa, A., Smeets, H.J., Smeets, L., de Smet, A.A., de Smit, P., Smit, P.C., Smits, T.M., Snoeijs, M.G., Sondakh, A.O., van der Steenhoven, T.J., van Sterkenburg, S.M., Stigter, D.A., Stigter, H., Strating, R.P., Stultiëns, G.N., Sybrandy, J.E., Teijink, J.A., Telgenkamp, B.J., Testroote, M.J., The, R.M., Thijsse, W.J., Tielliu, I.F., van Tongeren, R.B., Toorop, R.J., Tordoir, J.H., Tournoij, E., Truijers, M., Türkcan, K., Tutein Nolthenius, R.P., Ünlü, Ç., Vafi, A.A., Vahl, A.C., Veen, E.J., Veger, H.T., Veldman, M.G., Verhagen, H.J., Verhoeven, B.A., Vermeulen, C.F., Vermeulen, E.G., Vierhout, B.P., Visser, M.J., van der Vliet, J.A., Vlijmen - van Keulen, C.J., Voesten, H.G., Voorhoeve, R., Vos, A.W., de Vos, B., Vos, G.A., Vriens, B.H., Vriens, P.W., de Vries, A.C., de Vries, J.P., de Vries, M., van der Waal, C., Waasdorp, E.J., Wallis de Vries, B.M., van Walraven, L.A., van Wanroij, J.L., Warlé, M.C., van Weel, V., van Well, A.M., Welten, G.M., Welten, R.J., Wever, J.J., Wiersema, A.M., Wikkeling, O.R., Willaert, W.I., Wille, J., Willems, M.C., Willigendael, E.M., Wisselink, W., Witte, M.E., Wittens, C.H., Wolf-de Jonge, I.C., Yazar, O., Zeebregts, C.J., and van Zeeland, M.L.

Published
2020
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11. “Your brain can’t wait”: perspectives of children and adolescents with acquired brain injury and their parents on physical rehabilitation during the subacute phase

Author

Revalidatiegeneeskunde Onderzoek, Brain, Child Health, Psychosociale zorg patientenzorg, Kinderbewegingszorg patientenzorg, Revalidatie Medisch Kinderen, Gmelig Meyling, Christiaan, Verschuren, Olaf, Rentinck, Ingrid C.M., van Driel, Dimara, te Slaa, Esmée, Engelbert, Raoul H., Gorter, Jan Willem, Revalidatiegeneeskunde Onderzoek, Brain, Child Health, Psychosociale zorg patientenzorg, Kinderbewegingszorg patientenzorg, Revalidatie Medisch Kinderen, Gmelig Meyling, Christiaan, Verschuren, Olaf, Rentinck, Ingrid C.M., van Driel, Dimara, te Slaa, Esmée, Engelbert, Raoul H., and Gorter, Jan Willem

Published
2024

12. Toward Optimizing Risk Adjustment in the Dutch Surgical Aneurysm Audit

Author

Van den Akker, L.H., Van den Akker, P.J., Akkersdijk, G.J., Akkersdijk, G.P., Akkersdijk, W.L., van Andringa de Kempenaer, M.G., Arts, C.H., Avontuur, J.A., Baal, J.G., Bakker, O.J., Balm, R., Barendregt, W.B., Bender, M.H., Bendermacher, B.L., van den Berg, M., Berger, P., Beuk, R.J., Blankensteijn, J.D., Bleker, R.J., Bockel, J.H., Bodegom, M.E., Bogt, K.E., Boll, A.P., Booster, M.H., Borger van der Burg, B.L., de Borst, G.J., Bos-van Rossum, W.T., Bosma, J., Botman, J.M., Bouwman, L.H., Breek, J.C., Brehm, V., Brinckman, M.J., van den Broek, T.H., Brom, H.L., de Bruijn, M.T., de Bruin, J.L., Brummel, P., van Brussel, J.P., Buijk, S.E., Buimer, M.G., Burger, D.H., Buscher, H.C., den Butter, G., Cancrinus, E., Castenmiller, P.H., Cazander, G., Coveliers, H.M., Cuypers, P.H., Daemen, J.H., Dawson, I., Derom, A.F., Dijkema, A.R., Diks, J., Dinkelman, M.K., Dirven, M., Dolmans, D.E., van Doorn, R.C., van Dortmont, L.M., van der Eb, M.M., Eefting, D., van Eijck, G.J., Elshof, J.W., Elsman, B.H., van der Elst, A., van Engeland, M.I., van Eps, R.G., Faber, M.J., de Fijter, W.M., Fioole, B., Fritschy, W.M., Geelkerken, R.H., van Gent, W.B., Glade, G.J., Govaert, B., Groenendijk, R.P., de Groot, H.G., van den Haak, R.F., de Haan, E.F., Hajer, G.F., Hamming, J.F., van Hattum, E.S., Hazenberg, C.E., Hedeman Joosten, P.P., Helleman, J.N., van der Hem, L.G., Hendriks, J.M., van Herwaarden, J.A., Heyligers, J.M., Hinnen, J.W., Hissink, R.J., GH, Ho, den Hoed, P.T., Hoedt, M.T., van Hoek, F., Hoencamp, R., Hoffmann, W.H., Hoksbergen, A.W., Hollander, E.J., Huisman, L.C., Hulsebos, R.G., Huntjens, K.M., Idu, M.M., Jacobs, M.J., van der Jagt, M.F., Jansbeken, J.R., Janssen, R.J., Jiang, H.H., de Jong, S.C., Jongkind, V., Kapma, M.R., Keller, B.P., Khodadade Jahrome, A., Kievit, J.K., Klemm, P.L., Klinkert, P., Knippenberg, B., Koedam, N.A., Koelemaij, M.J., Kolkert, J.L., Koning, G.G., Koning, O.H., Krasznai, A.G., Krol, R.M., Kropman, R.H., Kruse, R.R., van der Laan, L., van der Laan, M.J., van Laanen, J.H., Lardenoye, J.H., Lawson, J.A., Legemate, D.A., Leijdekkers, V.J., Lemson, M.S., Lensvelt, M.M., Lijkwan, M.A., Lind, R.C., van der Linden, F.T., Liqui Lung, P.F., Loos, M.J., Loubert, M.C., Mahmoud, D.E., Manshanden, C.G., Mattens, E.C., Meerwaldt, R., Mees, B.M., Metz, R., Minnee, R.C., de Mol van Otterloo, J.C., Moll, F.L., Montauban van Swijndregt, Y.C., Morak, M.J., van de Mortel, R.H., Mulder, W., Nagesser, S.K., Naves, C.C., Nederhoed, J.H., Nevenzel-Putters, A.M., de Nie, A.J., Nieuwenhuis, D.H., Nieuwenhuizen, J., van Nieuwenhuizen, R.C., Nio, D., Oomen, A.P., Oranen, B.I., Oskam, J., Palamba, H.W., Peppelenbosch, A.G., van Petersen, A.S., Peterson, T.F., Petri, B.J., Pierie, M.E., Ploeg, A.J., Pol, R.A., Ponfoort, E.D., Poyck, P.P., Prent, A., ten Raa, S., Raymakers, J.T., Reichart, M., Reichmann, B.L., Reijnen, M.M., Rijbroek, A., van Rijn, M.J., de Roo, R.A., Rouwet, E.V., Rupert, C.G., Saleem, B.R., van Sambeek, M.R., Samyn, M.G., van 't Sant, H.P., van Schaik, J., van Schaik, P.M., Scharn, D.M., Scheltinga, M.R., Schepers, A., Schlejen, P.M., Schlosser, F.J., Schol, F.P., Schouten, O., Schreinemacher, M.H., Schreve, M.A., Schurink, G.W., Sikkink, C.J., Siroen, M.P., te Slaa, A., Smeets, H.J., Smeets, L., de Smet, A.A., de Smit, P., Smit, P.C., Smits, T.M., Snoeijs, M.G., Sondakh, A.O., van der Steenhoven, T.J., van Sterkenburg, S.M., Stigter, D.A., Stigter, H., Strating, R.P., Stultiëns, G.N., Sybrandy, J.E., Teijink, J.A., Telgenkamp, B.J., Testroote, M.J., The, R.M., Thijsse, W.J., Tielliu, I.F., van Tongeren, R.B., Toorop, R.J., Tordoir, J.H., Tournoij, E., Truijers, M., Türkcan, K., Tutein Nolthenius, R.P., Ünlü, Ç., Vafi, A.A., Vahl, A.C., Veen, E.J., Veger, H.T., Veldman, M.G., Verhagen, H.J., Verhoeven, B.A., Vermeulen, C.F., Vermeulen, E.G., Vierhout, B.P., Visser, M.J., van der Vliet, J.A., Vlijmen - van Keulen, C.J., Voesten, H.G., Voorhoeve, R., Vos, A.W., de Vos, B., Vos, G.A., Vriens, B.H., PW, Vriens, de Vries, A.C., de Vries, J.P., de Vries, M., van der Waal, C., Waasdorp, E.J., Wallis de Vries, B.M., van Walraven, L.A., van Wanroij, J.L., Warlé, M.C., van Weel, V., van Well, A.M., Welten, G.M., Welten, R.J., Wever, J.J., Wiersema, A.M., Wikkeling, O.R., Willaert, W.I., Wille, J., Willems, M.C., Willigendael, E.M., Wisselink, W., Witte, M.E., Wittens, C.H., Wolf-de Jonge, I.C., Yazar, O., Zeebregts, C.J., van Zeeland, M.L., Lijftogt, Niki, Vahl, Anco, van der Willik, Esmee M., Leijdekkers, Vanessa J., Wouters, Michel W.J.M., and Hamming, Jaap F.

Published
2019
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14. Failure to Rescue – a Closer Look at Mortality Rates Has No Added Value for Hospital Comparisons but Is Useful for Team Quality Assessment in Abdominal Aortic Aneurysm Surgery in The Netherlands

Author

Van den Akker, L.H., Van den Akker, P.J., Akkersdijk, G.J., Akkersdijk, G.P., Akkersdijk, W.L., van Andringa de Kempenaer, M.G., Arts, C.H., Avontuur, J.A., Baal, J.G., Bakker, O.J., Balm, R., Barendregt, W.B., Bender, M.H., Bendermacher, B.L., van den Berg, M., Berger, P., Beuk, R.J., Blankensteijn, J.D., Bleker, R.J., Bockel, J.H., Bodegom, M.E., Bogt, K.E., Boll, A.P., Booster, M.H., Borger van der Burg, B.L., de Borst, G.J., Bos-van Rossum, W.T., Bosma, J., Botman, J.M., Bouwman, L.H., Breek, J.C., Brehm, V., Brinckman, M.J., van den Broek, T.H., Brom, H.L., de Bruijn, M.T., de Bruin, J.L., Brummel, P., van Brussel, J.P., Buijk, S.E., Buimer, M.G., Burger, D.H., Buscher, H.C., den Butter, G., Cancrinus, E., Castenmiller, P.H., Cazander, G., Coveliers, H.M., Cuypers, P.H., Daemen, J.H., Dawson, I., Derom, A.F., Dijkema, A.R., Diks, J., Dinkelman, M.K., Dirven, M., Dolmans, D.E., van Doorn, R.C., van Dortmont, L.M., van der Eb, M.M., Eefting, D., van Eijck, G.J., Elshof, J.W., Elsman, B.H., van der Elst, A., van Engeland, M.I., van Eps, R.G., Faber, M.J., de Fijter, W.M., Fioole, B., Fritschy, W.M., Geelkerken, R.H., van Gent, W.B., Glade, G.J., Govaert, B., Groenendijk, R.P., de Groot, H.G., van den Haak, R.F., de Haan, E.F., Hajer, G.F., Hamming, J.F., van Hattum, E.S., Hazenberg, C.E., Hedeman Joosten, P.P., Helleman, J.N., van der Hem, L.G., Hendriks, J.M., van Herwaarden, J.A., Heyligers, J.M., Hinnen, J.W., Hissink, R.J., Ho, G.H., den Hoed, P.T., Hoedt, M.T., van Hoek, F., Hoencamp, R., Hoffmann, W.H., Hoksbergen, A.W., Hollander, E.J., Huisman, L.C., Hulsebos, R.G., Huntjens, K.M., Idu, M.M., Jacobs, M.J., van der Jagt, M.F., Jansbeken, J.R., Janssen, R.J., Jiang, H.H., de Jong, S.C., Jongkind, V., Kapma, M.R., Keller, B.P., Khodadade Jahrome, A., Kievit, J.K., Klemm, P.L., Klinkert, P., Knippenberg, B., Koedam, N.A., Koelemaij, M.J., Kolkert, J.L., Koning, G.G., Koning, O.H., Krasznai, A.G., Krol, R.M., Kropman, R.H., Kruse, R.R., van der Laan, L., van der Laan, M.J., van Laanen, J.H., Lardenoye, J.H., Lawson, J.A., Legemate, D.A., Leijdekkers, V.J., Lemson, M.S., Lensvelt, M.M., Lijkwan, M.A., Lind, R.C., van der Linden, F.T., Liqui Lung, P.F., Loos, M.J., Loubert, M.C., Mahmoud, D.E., Manshanden, C.G., Mattens, E.C., Meerwaldt, R., Mees, B.M., Metz, R., Minnee, R.C., de Mol van Otterloo, J.C., Moll, F.L., Montauban van Swijndregt, Y.C., Morak, M.J., van de Mortel, R.H., Mulder, W., Nagesser, S.K., Naves, C.C., Nederhoed, J.H., Nevenzel-Putters, A.M., de Nie, A.J., Nieuwenhuis, D.H., Nieuwenhuizen, J., van Nieuwenhuizen, R.C., Nio, D., Oomen, A.P., Oranen, B.I., Oskam, J., Palamba, H.W., Peppelenbosch, A.G., van Petersen, A.S., Peterson, T.F., Petri, B.J., Pierie, M.E., Ploeg, A.J., Pol, R.A., Ponfoort, E.D., Poyck, P.P., Prent, A., ten Raa, S., Raymakers, J.T., Reichart, M., Reichmann, B.L., Reijnen, M.M., Rijbroek, A., van Rijn, M.J., de Roo, R.A., Rouwet, E.V., Rupert, C.G., Saleem, B.R., van Sambeek, M.R., Samyn, M.G., van ’t Sant, H.P., van Schaik, J., van Schaik, P.M., Scharn, D.M., Scheltinga, M.R., Schepers, A., Schlejen, P.M., Schlosser, F.J., Schol, F.P., Schouten, O., Schreinemacher, M.H., Schreve, M.A., Schurink, G.W., Sikkink, C.J., Siroen, M.P., te Slaa, A., Smeets, H.J., Smeets, L., de Smet, A.A., de Smit, P., Smit, P.C., Smits, T.M., Snoeijs, M.G., Sondakh, A.O., van der Steenhoven, T.J., van Sterkenburg, S.M., Stigter, D.A., Stigter, H., Strating, R.P., Stultiëns, G.N., Sybrandy, J.E., Teijink, J.A., Telgenkamp, B.J., Testroote, M.J., The, R.M., Thijsse, W.J., Tielliu, I.F., van Tongeren, R.B., Toorop, R.J., Tordoir, J.H., Tournoij, E., Truijers, M., Türkcan, K., Tutein Nolthenius, R.P., Ünlü, Ç., Vafi, A.A., Vahl, A.C., Veen, E.J., Veger, H.T., Veldman, M.G., Verhagen, H.J., Verhoeven, B.A., Vermeulen, C.F., Vermeulen, E.G., Vierhout, B.P., Visser, M.J., van der Vliet, J.A., Vlijmen-van Keulen, C.J., Voesten, H.G., Voorhoeve, R., Vos, A.W., de Vos, B., Vos, G.A., Vriens, B.H., Vriens, P.W., de Vries, A.C., de Vries, J.P., de Vries, M., van der Waal, C., Waasdorp, E.J., Wallis de Vries, B.M., van Walraven, L.A., van Wanroij, J.L., Warlé, M.C., van Weel, V., van Well, A.M., Welten, G.M., Welten, R.J., Wever, J.J., Wiersema, A.M., Wikkeling, O.R., Willaert, W.I., Wille, J., Willems, M.C., Willigendael, E.M., Wisselink, W., Witte, M.E., Wittens, C.H., Wolf-de Jonge, I.C., Yazar, O., Zeebregts, C.J., van Zeeland, M.L., Lijftogt, Niki, Karthaus, Eleonora G., Vahl, Anco, van Zwet, Erik W., van der Willik, Esmee M., Tollenaar, Robertus A.E.M., Hamming, Jaap F., and Wouters, Michel W.J.M.

Published
2018
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16. The Dutch Audit of Carotid Interventions: Transparency in Quality of Carotid Endarterectomy in Symptomatic Patients in the Netherlands

Author

Van den Akker, L.H., Van den Akker, P.J., Akkersdijk, G.J., Akkersdijk, G.P., Akkersdijk, W.L., van Andringa de Kempenaer, M.G., Arts, C.H., Avontuur, J.A., Baal, J.G., Bakker, O.J., Balm, R., Barendregt, W.B., Bender, M.H., Bendermacher, B.L., van den Berg, M., Berger, P., Beuk, R.J., Blankensteijn, J.D., Bleker, R.J., Bockel, J.H., Bodegom, M.E., Bogt, K.E., Boll, A.P., Booster, M.H., Borger van der Burg, B.L., de Borst, G.J., Bos- van Rossum, W.T., Bosma, J., Botman, J.M., Bouwman, L.H., Breek, J.C., Brehm, V., Brinckman, M.J., van den Broek, T.H., Brom, H.L., de Bruijn, M.T., de Bruin, J.L., Brummel, P., van Brussel, J.P., Buijk, S.E., Buimer, M.G., Burger, D.H., Buscher, H.C., den Butter, G., Cancrinus, E., Castenmiller, P.H., Cazander, G., Coveliers, H.M., Cuypers, P.H., Daemen, J.H., Dawson, I., Derom, A.F., Dijkema, A.R., Diks, J., Dinkelman, M.K., Dirven, M., Dolmans, D.E., van Doorn, R.C., van Dortmont, L.M., van der Eb, M.M., Eefting, D., van Eijck, G.J., Elshof, J.W., Elsman, B.H., van der Elst, A., van Engeland, M.I., van Eps, R.G., Faber, M.J., de Fijter, W.M., Fioole, B., Fritschy, W.M., Geelkerken, R.H., van Gent, W.B., Glade, G.J., Govaert, B., Groenendijk, R.P., de Groot, H.G., van den Haak, R.F., de Haan, E.F., Hajer, G.F., Hamming, J.F., van Hattum, E.S., Hazenberg, C.E., Hedeman Joosten, P.P., Helleman, J.N., van der Hem, L.G., Hendriks, J.M., van Herwaarden, J.A., Heyligers, J.M., Hinnen, J.W., Hissink, R.J., Ho, G.H., den Hoed, P.T., Hoedt, M.T., van Hoek, F., Hoencamp, R., Hoffmann, W.H., Hoksbergen, A.W., Hollander, E.J., Huisman, L.C., Hulsebos, R.G., Huntjens, K.M., Idu, M.M., Jacobs, M.J., van der Jagt, M.F., Jansbeken, J.R., Janssen, R.J., Jiang, H.H., de Jong, S.C., Jongkind, V., Kapma, M.R., Keller, B.P., Khodadade Jahrome, A., Kievit, J.K., Klemm, P.L., Klinkert, P., Knippenberg, B., Koedam, N.A., Koelemaij, M.J., Kolkert, J.L., Koning, G.G., Koning, O.H., Krasznai, A.G., Krol, R.M., Kropman, R.H., Kruse, R.R., van der Laan, L., van der Laan, M.J., van Laanen, J.H., Lardenoye, J.H., Lawson, J.A., Legemate, D.A., Leijdekkers, V.J., Lemson, M.S., Lensvelt, M.M., Lijkwan, M.A., Lind, R.C., van der Linden, F.T., Liqui Lung, P.F., Loos, M.J., Loubert, M.C., Mahmoud, D.E., Manshanden, C.G., Mattens, E.C., Meerwaldt, R., Mees, B.M., Metz, R., Minnee, R.C., de Mol van Otterloo, J.C., Moll, F.L., Montauban van Swijndregt, Y.C., Morak, M.J., van de Mortel, R.H., Mulder, W., Nagesser, S.K., Naves, C.C., Nederhoed, J.H., Nevenzel-Putters, A.M., de Nie, A.J., Nieuwenhuis, D.H., Nieuwenhuizen, J., van Nieuwenhuizen, R.C., Nio, D., Oomen, A.P., Oranen, B.I., Oskam, J., Palamba, H.W., Peppelenbosch, A.G., van Petersen, A.S., Peterson, T.F., Petri, B.J., Pierie, M.E., Ploeg, A.J., Pol, R.A., Ponfoort, E.D., Poyck, P.P., Prent, A., ten Raa, S., Raymakers, J.T., Reichart, M., Reichmann, B.L., Reijnen, M.M., Rijbroek, A., van Rijn, M.J., de Roo, R.A., Rouwet, E.V., Rupert, C.G., Saleem, B.R., van Sambeek, M.R., Samyn, M.G., van 't Sant, H.P., van Schaik, J., van Schaik, P.M., Scharn, D.M., Scheltinga, M.R., Schepers, A., Schlejen, P.M., Schlosser, F.J., Schol, F.P., Schouten, O., Schreinemacher, M.H., Schreve, M.A., Schurink, G.W., Sikkink, C.J., Siroen, M.P., te Slaa, A., Smeets, H.J., Smeets, L., de Smet, A.A., de Smit, P., Smit, P.C., Smits, T.M., Snoeijs, M.G., Sondakh, A.O., van der Steenhoven, T.J., van Sterkenburg, S.M., Stigter, D.A., Stigter, H., Strating, R.P., Stultiëns, D., Sybrandy, J.E., Teijink, J.A., Telgenkamp, B.J., Testroote, M.J., The, R.M., Thijsse, W.J., Tielliu, I.F., van Tongeren, R.B., Toorop, R.J., Tordoir, J.H., Tournoij, E., Truijers, M., Türkcan, K., Tutein Nolthenius, R.P., Ünlü, Ç., Vafi, A.A., Vahl, A.C., Veen, E.J., Veger, H.T., Veldman, M.G., Verhagen, H.J., Verhoeven, B.A., Vermeulen, C.F., Vermeulen, E.G., Vierhout, B.P., Visser, M.J., van der Vliet, J.A., Vlijmen - van Keulen, C.J., Voesten, H.G., Voorhoeve, R., Vos, A.W., de Vos, B., Vos, G.A., Vriens, B.H., Vriens, P.W., de Vries, A.C., de Vries, J.P., de Vries, M., van der Waal, C., Waasdorp, E.J., Wallis de Vries, B.M., van Walraven, L.A., van Wanroij, J.L., Warlé, M.C., van Weel, V., van Well, A.M., Welten, G.M., Welten, R.J., Wever, J.J., Wiersema, A.M., Wikkeling, O.R., Willaert, W.I., Wille, J., Willems, M.C., Willigendael, E.M., Wisselink, W., Witte, M.E., Wittens, C.H., Wolf-de Jonge, I.C., Yazar, O., Zeebregts, C.J., van Zeeland, M.L., de Borst, Gert J., Elsman, Bernard H.P., Elshof, Jan-Willem, Geelkerken, Robert H., Hamming, Jaap F., Vahl, Anco, Willems, Martine C., Karthaus, Eleonora G., Kuhrij, Laurien S., and Wouters, Michel W.J.M.

Published
2018
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22. Association of Hospital Volume with Perioperative Mortality of Endovascular Repair of Complex Aortic Aneurysms: A Nationwide Cohort Study

Author

Alberga, Anna J., von Meijenfeldt, Gerdine C. I., Rastogi, Vinamr, de Bruin, Jorg L., Wever, Jan J., van Herwaarden, Joost A., Hamming, Jaap F., Hazenberg, Constantijn E. V. B., van Schaik, Jan, Mees, Barend M. E., van der Laan, Maarten J., Zeebregts, Clark J., Schurink, Geert W. H., Verhagen, Hence J. M., van den Akker, P. J., Akkersdijk, G. P., Akkersdijk, W. L., van Andringa de Kempenaer, M. G., Arts, C. H. P., Avontuur, A. M., Bakker, O. J., Balm, R., Barendregt, W. B., Bekken, J. A., Bender, M. H. M., Bendermacher, B. L. W., van den Berg, M., Beuk, R. J., Blankensteijn, J. D., Bode, A. S., Bodegom, M. E., van der Bogt, K. E. A., Boll, A. P. M., Booster, M. H., Borger van der Burg, B. L. S., de Borst, G. J., Bos-van Rossum, W. T. G. J., Bosma, J., Botman, J. M. J., Bouwman, L. H., Brehm, V., de Bruijn, M. T., de Bruin, J. L., Brummel, P., van Brussel, J. P., Buijk, S. E., Buimer, M. G., Buscher, H. C. J. L., Cancrinus, E., Castenmiller, P. H., Cazander, G., Cuypers, P. W. M., Daemen, J. H. C., Dawson, I., Dierikx, J. E., Dijkstra, M. L., Diks, J., Dinkelman, M. K., Dirven, M., Dolmans, D. E. J. G. J., van Dortmont, L. M. C., Drouven, J. W., van der Eb, M. M., Eefting, D., van Eijck, G. J. W. M., Elshof, J. W. M., Elsman, A. H. P., van der Elst, A., van Engeland, M. I. A., van Eps, G. S., Faber, M. J., de Fijter, W. M., Fioole, B., Fritschy, W. M., Fung Kon Jin, P. H. P., Geelkerken, R. H., van Gent, W. B., Glade, G. J., Govaert, B., Groenendijk, R. P. R., de Groot, H. G. W., van den Haak, R. F. F., de Haan, E. F. A., Hajer, G. F., Hamming, J. F., van Hattum, E. S., Hazenberg, C. E. V. B., Hedeman Joosten, P. P. A., Helleman, J. N., van der Hem, L. G., Hendriks, J. M., van Herwaarden, J. A., Heyligers, J. M. M., Hinnen, J. W., Hissink, R. J., Ho, G. H., den Hoed, P. T., Hoedt, M. T. C., van Hoek, F., Hoencamp, R., Hoffmann, W. H., Hoksbergen, A. W. J., Hollander, E. J. F., Huisman, L. C., Hulsebos, R. G., Huntjens, K. M. B., Idu, M. M., Jacobs, M. J. H. M., van der Jagt, M. F. P., Jansbeken, J. R. H., Janssen, R. J. L., Jiang, H. H. L., de Jong, S. C., Jongbloed-Winkel, T. A., Jongkind, V., Kapma, M. R., Keller, B. P. J. A., Jahrome, A. Khodadade, Kievit, J. K., Klemm, P. L., Klinkert, P., Koedam, N. A., Koelemaij, M. J. W., Kolkert, J. L. P., Koning, G. G., Koning, O. H. J., Konings, R., Krasznai, A. G., Kropman, R. H. J., Kruse, R. R., van der Laan, L., van der Laan, M. J., van Laanen, J. H. H., van Lammeren, G. W., Lamprou, D. A. A., Lardenoije, J. H. P., Lauret, G. J., Leenders, B. J. M., Legemate, D. A., Leij-Dekkers, V. J., Lemson, M. S., Lensvelt, M. M. A., Lijkwan, M. A., van der Linden, F. T. P. M., Lung, P. F. L., Loos, M. J. A., Loubert, M. C., van de Luijtgaarden, K. M., Mahmoud, D. E. A. K., Manshanden, C. G., Mat-Tens, E. C. J. L., Meerwaldt, R., Mees, B. M. E., Menting, T. P., Metz, R., de Mol van Otterloo, J. C. A., Molegraaf, M. J., Montauban van Swijn-Dregt, Y. C. A., Morak, M. J. M., van de Mortel, R. H. W., Mulder, W., Nagesser, S. K., Naves, C. C. L. M., Nederhoed, J. H., Nevenzel, A. M., de Nie, A. J., Nieuwenhuis, D. H., van Nieuwenhuizen, R. C., Nieuwenhui-Zen, J., Nio, D., Oomen, A. P. A., Oranen, B. I., Oskam, J., Palamba, H. W., Peppelenbosch, A. G., van Petersen, A. S., Petri, B. J., Pierie, M. E. N., Ploeg, A. J., Pol, R. A., Ponfoort, E. D., Poyck, P. P. C., Prent, A., ten Raa, S., Raymakers, J. T. F. J., Reichmann, B. L., Reijnen, M. M. P. J., de Ridder, J. A. M., Rijbroek, A., van Rijn, M. J. E., de Roo, R. A., Rouwet, E. V., Saleem, B. R., van Sambeek, M. R. H. M., Samyn, M. G., van't Sant, H. P., van Schaik, J., van Schaik, P. M., Scharn, D. M., Scheltinga, M. R. M., Schepers, A., Schlejen, P. M., Schlösser, F. J. V., Schol, F. P. G., Scholtes, V. P. W., Schouten, O., Schreve, M. A., Schurink, G. W. H., Sikkink, C. J. J. M., te Slaa, A., Smeets, H. J., Smeets, L., Smeets, R. R., de Smet, A. A. E. A., Smit, P. C., Smits, T. M., Snoeijs, M. G. J., Sondakh, A. O., Speijers, M. J., van der Steenhoven, T. J., van Sterkenburg, S. M. M., Stigter, D. A. A., Stokmans, R. A., Strating, R. P., Stultiëns, G. N. M., Sybrandy, J. E. M., Teijink, J. A. W., Telgenkamp, B. J., Testroote, M. J. G., Tha-in, T., The, R. M., Thijsse, W. J., Thomassen, I., Tielliu, I. F. J., van Tongeren, R. B. M., Toorop, R. J., Tournoij, E., Truijers, M., Türkcan, K., Nolthenius, R. P. Tutein, Ünlü, C., Vaes, R. H. D., Vahl, A. C., Veen, E. J., Veger, H. T. C., Veldman, M. G., Verhagen, H. J. M., Verhoeven, B. A. N., Vermeulen, C. F. W., Vermeulen, E. G. J., Vierhout, B. P., van der Vijver-Coppen, R. J., Visser, M. J. T., van der Vliet, J. A., van Vlijmen-van Keulen, C. J., van der Vorst, J. R., Vos, A. W. F., Vos, C. G., Vos, G. A., de Vos, B., Voûte, M. T., Vriens, B. H. R., Vriens, P. W. H. E., de Vries, D. K., de Vries, J. P. P. M., de Vries, M., de Vries, A. C., van der Waal, C., Waasdorp, E. J., de Vries, B. M. Wallis, van Walraven, L. A., van Wanroi, J. L., Warlé, M. C., van Weel, V., van Well, A. M. E., Welten, G. M. J. M., Wever, J. J., Wiersema, A. M., Wikkeling, O. R. M., Willaert, W. I. M., Wille, J., Willems, M. C. M., Willigendael, E. M., Wilschut, E. D., Wisselink, W., Witte, M. E., Wittens, C. H. A., Wong, C. Y., Yazar, O., Yeung, K. K., Zeebregts, C. J. A. M., van Zeeland, M. L. P., Physiology, ACS - Pulmonary hypertension & thrombosis, Surgery, ACS - Atherosclerosis & ischemic syndromes, ACS - Microcirculation, VU University medical center, AII - Inflammatory diseases, APH - Digital Health, Medical Biochemistry, ACS - Diabetes & metabolism, AII - Infectious diseases, and AGEM - Amsterdam Gastroenterology Endocrinology Metabolism

Subjects
volume-outcome, complex AAA, endovascular, mortality
Abstract

Objective: We evaluate nationwide perioperative outcomes of complex EVAR and assess the volume-outcome association of complex EVAR. Summary of Background Data: Endovascular treatment with fenestrated (FEVAR) or branched (BEVAR) endografts is progressively used for excluding complex aortic aneurysms (complex AAs). It is unclear if a volumeoutcome association exists in endovascular treatment of complex AAs (complex EVAR). Methods: All patients prospectively registered in the Dutch Surgical Aneurysm Audit who underwent complex EVAR (FEVAR or BEVAR) between January 2016 and January 2020 were included. The effect of annual hospital volume on perioperative mortality was examined using multivariable logistic regression analyses. Patients were stratified into quartiles based on annual hospital volume to determine hospital volume categories. Results: We included 694 patients (539 FEVAR patients, 155 BEVAR patients). Perioperative mortality following FEVAR was 4.5% and 5.2% following BEVAR. Postoperative complication rates were 30.1% and 48.7%, respectively. The first quartile hospitals performed

Published
2023
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29. Editor's Choice – Nationwide Analysis of Patients Undergoing Iliac Artery Aneurysm Repair in the Netherlands

Author

Hamid Jalalzadeh, Reza Indrakusuma, Mark J.W. Koelemay, Ron Balm, L.H. Van den Akker, P.J. Van den Akker, G.J. Akkersdijk, G.P. Akkersdijk, W.L. Akkersdijk, M.G. van Andringa de Kempenaer, C.H. Arts, J.A. Avontuur, J.G. Baal, O.J. Bakker, R. Balm, W.B. Barendregt, M.H. Bender, B.L. Bendermacher, M. van den Berg, P. Berger, R.J. Beuk, J.D. Blankensteijn, R.J. Bleker, J.H. Bockel, M.E. Bodegom, K.E. Bogt, A.P. Boll, M.H. Booster, B.L. Borger van der Burg, G.J. de Borst, W.T. Bos-van Rossum, J. Bosma, J.M. Botman, L.H. Bouwman, J.C. Breek, V. Brehm, M.J. Brinckman, T.H. van den Broek, H.L. Brom, M.T. de Bruijn, J.L. de Bruin, P. Brummel, J.P. van Brussel, S.E. Buijk, M.G. Buimer, D.H. Burger, H.C. Buscher, G. den Butter, E. Cancrinus, P.H. Castenmiller, G. Cazander, H.M. Coveliers, P.H. Cuypers, J.H. Daemen, I. Dawson, A.F. Derom, A.R. Dijkema, J. Diks, M.K. Dinkelman, M. Dirven, D.E. Dolmans, R.C. van Doorn, L.M. van Dortmont, M.M. van der Eb, D. Eefting, G.J. van Eijck, J.W. Elshof, B.H. Elsman, A. van der Elst, M.I. van Engeland, R.G. van Eps, M.J. Faber, W.M. de Fijter, B. Fioole, W.M. Fritschy, R.H. Geelkerken, W.B. van Gent, G.J. Glade, B. Govaert, R.P. Groenendijk, H.G. de Groot, R.F. van den Haak, E.F. de Haan, G.F. Hajer, J.F. Hamming, E.S. van Hattum, C.E. Hazenberg, P.P. Hedeman Joosten, J.N. Helleman, L.G. van der Hem, J.M. Hendriks, J.A. van Herwaarden, J.M. Heyligers, J.W. Hinnen, R.J. Hissink, G.H. Ho, P.T. den Hoed, M.T. Hoedt, F. van Hoek, R. Hoencamp, W.H. Hoffmann, A.W. Hoksbergen, E.J. Hollander, L.C. Huisman, R.G. Hulsebos, K.M. Huntjens, M.M. Idu, M.J. Jacobs, M.F. van der Jagt, J.R. Jansbeken, R.J. Janssen, H.H. Jiang, S.C. de Jong, V. Jongkind, M.R. Kapma, B.P. Keller, A. Khodadade Jahrome, J.K. Kievit, P.L. Klemm, P. Klinkert, B. Knippenberg, N.A. Koedam, M.J. Koelemay, J.L. Kolkert, G.G. Koning, O.H. Koning, A.G. Krasznai, R.M. Krol, R.H. Kropman, R.R. Kruse, L. van der Laan, M.J. van der Laan, J.H. van Laanen, J.H. Lardenoye, J.A. Lawson, D.A. Legemate, V.J. Leijdekkers, M.S. Lemson, M.M. Lensvelt, M.A. Lijkwan, R.C. Lind, F.T. van der Linden, P.F. Liqui Lung, M.J. Loos, M.C. Loubert, D.E. Mahmoud, C.G. Manshanden, E.C. Mattens, R. Meerwaldt, B.M. Mees, R. Metz, R.C. Minnee, J.C. de Mol van Otterloo, F.L. Moll, Y.C. Montauban van Swijndregt, M.J. Morak, R.H. van de Mortel, W. Mulder, S.K. Nagesser, C.C. Naves, J.H. Nederhoed, A.M. Nevenzel-Putters, A.J. de Nie, D.H. Nieuwenhuis, J. Nieuwenhuizen, R.C. van Nieuwenhuizen, D. Nio, A.P. Oomen, B.I. Oranen, J. Oskam, H.W. Palamba, A.G. Peppelenbosch, A.S. van Petersen, T.F. Peterson, B.J. Petri, M.E. Pierie, A.J. Ploeg, R.A. Pol, E.D. Ponfoort, P.P. Poyck, A. Prent, S. ten Raa, J.T. Raymakers, M. Reichart, B.L. Reichmann, M.M. Reijnen, A. Rijbroek, M.J. van Rijn, R.A. de Roo, E.V. Rouwet, C.G. Rupert, B.R. Saleem, M.R. van Sambeek, M.G. Samyn, H.P. van ’t Sant, J. van Schaik, P.M. van Schaik, D.M. Scharn, M.R. Scheltinga, A. Schepers, P.M. Schlejen, F.J. Schlosser, F.P. Schol, O. Schouten, M.H. Schreinemacher, M.A. Schreve, G.W. Schurink, C.J. Sikkink, M.P. Siroen, A. te Slaa, H.J. Smeets, L. Smeets, A.A. de Smet, P. de Smit, P.C. Smit, T.M. Smits, M.G. Snoeijs, A.O. Sondakh, T.J. van der Steenhoven, S.M. van Sterkenburg, D.A. Stigter, H. Stigter, R.P. Strating, G.N. Stultiëns, J.E. Sybrandy, J.A. Teijink, B.J. Telgenkamp, M.J. Testroote, R.M. The, W.J. Thijsse, I.F. Tielliu, R.B. van Tongeren, R.J. Toorop, J.H. Tordoir, E. Tournoij, M. Truijers, K. Türkcan, R.P. Tutein Nolthenius, Ç. Ünlü, A.A. Vafi, A.C. Vahl, E.J. Veen, H.T. Veger, M.G. Veldman, H.J. Verhagen, B.A. Verhoeven, C.F. Vermeulen, E.G. Vermeulen, B.P. Vierhout, M.J. Visser, J.A. van der Vliet, C.J. Vlijmen - van Keulen, H.G. Voesten, R. Voorhoeve, A.W. Vos, B. de Vos, G.A. Vos, B.H. Vriens, P.W. Vriens, A.C. de Vries, J.P. de Vries, M. de Vries, C. van der Waal, E.J. Waasdorp, B.M. Wallis de Vries, L.A. van Walraven, J.L. van Wanroij, M.C. Warlé, V. van Weel, A.M. van Well, G.M. Welten, R.J. Welten, J.J. Wever, A.M. Wiersema, O.R. Wikkeling, W.I. Willaert, J. Wille, M.C. Willems, E.M. Willigendael, W. Wisselink, M.E. Witte, C.H. Wittens, I.C. Wolf-de Jonge, O. Yazar, C.J. Zeebregts, M.L. van Zeeland, Surgery, ACS - Atherosclerosis & ischemic syndromes, Pathology, VU University medical center, Pediatrics, Dermatology, ACS - Microcirculation, ACS - Diabetes & metabolism, Graduate School, 02 Surgical specialisms, ​Robotics and image-guided minimally-invasive surgery (ROBOTICS), Neurology, Erasmus MC other, Molecular Genetics, Erasmus School of Economics, Socio-Medical Sciences (SMS), Cell biology, Gynecological Oncology, Research & Education, Child and Adolescent Psychiatry / Psychology, Cardiology, Urology, Erasmus School of Health Policy & Management, Erasmus School of Social and Behavioural Sciences, Erasmus School of Law, Department of History, Department of Psychology, Education and Child Studies, Obstetrics & Gynecology, Department of Finance, General Practice, Applied Economics, Pediatric Surgery, Department of Business-Society Management, Commercial Law and Financial Law, Radiology & Nuclear Medicine, Business Economics, Neurosurgery, Public Health, Anesthesiology, Internal Medicine, Hematology, Intensive Care, Psychiatry, WP ESPhil, and Gastroenterology & Hepatology

Subjects
Male, medicine.medical_specialty, medicine.medical_treatment, Iliac Aneurysm/epidemiology, Patient characteristics, Netherlands/epidemiology, 030204 cardiovascular system & hematology, 030230 surgery, Iliac Artery/pathology, Endovascular aneurysm repair, Iliac Artery, 03 medical and health sciences, 0302 clinical medicine, Aneurysm, Sex Factors, medicine, 80 and over, Humans, EVAR, Registries, Iliac artery aneurysm, Aged, Netherlands, Retrospective Studies, Surgical repair, Aged, 80 and over, business.industry, Open repair, Endovascular Procedures, Retrospective cohort study, Guideline, Vascular surgery, medicine.disease, Guideline Adherence/statistics & numerical data, Surgery, Endovascular Procedures/methods, Aneurysm repair, Treatment Outcome, Iliac Aneurysm, Female, Guideline Adherence, Cardiology and Cardiovascular Medicine, business
Abstract

OBJECTIVE: The new 2019 guideline of the European Society for Vascular Surgery (ESVS) recommends consideration for elective iliac artery aneurysm (eIAA) repair when the iliac diameter exceeds 3.5 cm, as opposed to 3.0 cm previously. The current study assessed diameters at time of eIAA repair and ruptured IAA (rIAA) repair and compared clinical outcomes after open surgical repair (OSR) and endovascular aneurysm repair (EVAR).METHODS: This retrospective observational study used the nationwide Dutch Surgical Aneurysm Audit (DSAA) registry that includes all patients who undergo aorto-iliac aneurysm repair in the Netherlands. All patients who underwent primary IAA repair between 1 January 2014 and 1 January 2018 were included. Diameters at time of eIAA and rIAA repair were compared in a descriptive fashion. The anatomical location of the IAA was not registered in the registry. Patient characteristics and outcomes of OSR and EVAR were compared with appropriate statistical tests.RESULTS: The DSAA registry comprised 974 patients who underwent IAA repair. A total of 851 patients were included after exclusion of patients undergoing revision surgery and patients with missing essential variables. eIAA repair was carried out in 713 patients, rIAA repair in 102, and symptomatic IAA repair in 36. OSR was performed in 205, EVAR in 618, and hybrid repairs and conversions in 28. The median maximum IAA diameter at the time of eIAA and rIAA repair was 43 (IQR 38-50) mm and 68 (IQR 58-85) mm, respectively. Mortality was 1.3% (95% CI 0.7-2.4) after eIAA repair and 25.5% (95% CI 18.0-34.7) after rIAA repair. Mortality was not significantly different between the OSR and EVAR subgroups. Elective OSR was associated with significantly more complications than EVAR (intra-operative: 9.8% vs. 3.6%, post-operative: 34.0% vs. 13.8%, respectively).CONCLUSION: In the Netherlands, most eIAA repairs are performed at diameters larger than recommended by the ESVS guideline. These findings appear to support the recent increase in the threshold diameter for eIAA repair.

Published
2020
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30. Nationwide Outcomes of Octogenarians Following Open or Endovascular Management After Ruptured Abdominal Aortic Aneurysms

Author

Anna J. Alberga, Jorg L. de Bruin, Frederico Bastos Gonçalves, Eleonora G. Karthaus, Janneke A. Wilschut, Joost A. van Herwaarden, Jan J. Wever, Hence J. M. Verhagen, Van den Akker PJ, Akkersdijk GJ, Akkersdijk GP, Akkersdijk WL, van Andringa de Kempenaer MG, Arts CH, Avontuur JA, Bakker OJ, Balm R, Barendregt WB, Bekken JA, Bender MH, Bendermacher BL, van den Berg M, Berger P, Beuk RJ, Blankensteijn JD, Bleker RJ, Blok JJ, Bode AS, Bodegom ME, van der Bogt KE, Boll AP, Booster MH, Borger van der Burg BL, de Borst GJ, Bos-van Rossum WT, Bosma J, Botman JM, Bouwman LH, Brehm V, de Bruijn MT, de Bruin JL, Brummel P, van Brussel JP, Buijk SE, Buijs MA, Buimer MG, Burger DH, Buscher HC, Cancrinus E, Castenmiller PH, Cazander G, Coester AM, Cuypers PH, Daemen JH, Dawson I, Dierikx JE, Dijkstra ML, Diks J, Dinkelman MK, Dirven M, Dolmans DE, van Doorn RC, van Dortmont LM, Drouven JW, van der Eb MM, Eefting D, van Eijck GJ, Elshof JW, Elsman BH, van der Elst A, van Engeland MI, van Eps RG, Faber MJ, de Fijter WM, Fioole B, Fokkema TM, Frans FA, Fritschy WM, Fung Kon Jin PH, Geelkerken RH, van Gent WB, Glade GJ, Govaert B, Groenendijk RP, de Groot HG, van den Haak RF, de Haan EF, Hajer GF, Hamming JF, van Hattum ES, Hazenberg CE, Hedeman Joosten PP, Helleman JN, van der Hem LG, Hendriks JM, van Herwaarden JA, Heyligers JM, Hinnen JW, Hissink RJ, Ho GH, den Hoed PT, Hoedt MT, van Hoek F, Hoencamp R, Hoffmann WH, Hogendoorn W, Hoksbergen AW, Hollander EJ, Hommes M, Hopmans CJ, Huisman LC, Hulsebos RG, Huntjens KM, Idu MM, Jacobs MJ, van der Jagt MF, Jansbeken JR, Janssen RJ, Jiang HH, de Jong SC, Jongbloed-Winkel TA, Jongkind V, Kapma MR, Keller BP, Khodadade Jahrome A, Kievit JK, Klemm PL, Klinkert P, Koedam NA, Koelemaij MJ, Kolkert JL, Koning GG, Koning OH, Konings R, Krasznai AG, Krol RM, Kropman RH, Kruse RR, van der Laan L, van der Laa n MJ, van Laanen JH, van Lammeren GW, Lamprou DA, Lardenoye JH, Lauret GJ, Leenders BJ, Legemate DA, Leijdekkers VJ, Lemson MS, Lensvelt MM, Lijkwan MA, Lind RC, van der Linden FT, Liqui Lung PF, Loos MJ, Loubert MC, van de Luijtgaarden KM, Mahmoud DE, Manshanden CG, Mattens EC, Meerwaldt R, Mees BM, von Meijenfeldt GC, Menting TP, Metz R, Minnee RC, de Mol van Otterloo JC, Molegraaf MJ, Montauban van Swijndregt YC, Morak MJ, van de Mortel RH, Mulder W, Nagesser SK, Naves CC, Nederhoed JH, Nevenzel-Putters AM, de Nie AJ, Nieuwenhuis DH, Nieuwenhuizen J, van Nieuwenhuizen RC, Nio D, Noyez VJ, Oomen AP, Oranen BI, Oskam J, Palamba HW, Peppelenbosch AG, van Petersen AS, Petri BJ, Pierie ME, Ploeg AJ, Pol RA, Ponfoort ED, Post IC, Poyck PP, Prent A, ten Raa S, Raymakers JT, Reichart M, Reichmann BL, Reijnen MM, de Ridder JA, Rijbroek A, van Rijn MJ, de Roo RA, Rouwet EV, Saleem BR, Salemans PB, van Sambeek MR, Samyn MG, van ‘t Sant HP, van Schaik J, van Schaik PM, Scharn DM, Scheltinga MR, Schepers A, Schlejen PM, Schlosser FJ, Schol FP, Scholtes VP, Schouten O, Schreve MA, Schurink GW, Sikkink CJ, te Slaa A, Smeets HJ, Smeets L, Smeets RR, de Smet AA, Smit PC, Smits TM, Snoeijs MG, Sondakh AO, Speijers MJ, van der Steenhoven TJ, van Sterkenburg SM, Stigter DA, Stokmans RA, Strating RP, Stultiëns GN, Sybrandy JE, Teijink JA, Telgenkamp BJ, Teraa M, Testroote MJ, Tha-In T, The RM, Thijsse WJ, Thomassen I, Tielliu IF, van Tongeren RB, Toorop RJ, Tournoij E, Truijers M, Türkcan K, Tutein Nolthenius RP, Ünlü Ç, Vaes RH, Vafi AA, Vahl AC, Veen EJ, Veger HT, Veldman MG, Velthuis S, Verhagen HJ, Verhoeven BA, Vermeulen CF, Vermeulen EG, Vierhout BP, van der Vijver-Coppen RJ, Visser MJ, van der Vliet JA, Vlijmen—van Keulen CJ, Voorhoeve R, van der Vorst JR, Vos AW, de Vos B, Vos CG, Vos GA, Voute MT, Vriens BH, Vriens PW, de Vries AC, de Vries DK, de Vries JP, de Vries M, van der Waal C, Waasdorp EJ, Wallis de Vries BM, van Walraven LA, van Wanroij JL, Warlé MC, van de Water W, van Weel V, van Well AM, Welten GM, Welten RJ, Wever JJ, Wiersema AM, Wikkeling OR, Willaert WI, Wille J, Willems MC, Willigendael EM, Wilschut ED, Wisselink W, Witte ME, Wittens CH, Wong CY, Wouda R, Yazar O, Yeung KK, Zeebregts CJ, van Zeeland ML, NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM), and Surgery

Subjects
Radiology, Nuclear Medicine and imaging, Surgery, Cardiology and Cardiovascular Medicine
Abstract

Purpose: Octogenarians are known to have less-favorable outcomes following ruptured abdominal aortic aneurysm (rAAA) repair compared with their younger counterparts. Accurate information regarding perioperative outcomes following rAAA-repair is important to evaluate current treatment practice. The aim of this study was to evaluate perioperative outcomes of octogenarians and to identify factors associated with mortality and major complications after open surgical repair (OSR) or endovascular aneurysm repair (EVAR) of a rAAA using nationwide, real-world, contemporary data. Methods: All patients that underwent EVAR or OSR of an infrarenal or juxtarenal rAAA between January 1, 2013, and December 31, 2018, were prospectively registered in the Dutch Surgical Aneurysm Audit (DSAA) and included in this study. The primary outcome was the comparison of perioperative outcomes of octogenarians versus non-octogenarians, including adjustment for confounders. Secondary outcomes were the identification of factors associated with mortality and major complications in octogenarians. Results: The study included 2879 patients, of which 1146 were treated by EVAR (382 octogenarians, 33%) and 1733 were treated by OSR (410 octogenarians, 24%). Perioperative mortality of octogenarians following EVAR was 37.2% versus 14.8% in non-octogenarians (adjusted OR=2.9, 95% CI=2.8–3.0) and 50.0% versus 29.4% following OSR (adjusted OR=2.2, 95% CI=2.2–2.3). Major complication rates of octogenarians were 55.4% versus 31.8% in non-octogenarians following EVAR (OR=2.7, 95% CI=2.1–3.4), and 68% versus 49% following OSR (OR=2.2, 95% CI=1.8–2.8). Following EVAR, 30.6% of the octogenarians had an uncomplicated perioperative course (UPC) versus 49.5% in non-octogenarians (OR=0.5, 95% CI=0.4–0.6), while following OSR, UPC rates were 20.7% in octogenarians versus 32.6% in non-octogenarians (OR=0.5, 95% CI=0.4–0.7). Cardiac or pulmonary comorbidity and loss of consciousness were associated with mortality and major complications in octogenarians. Interestingly, female octogenarians had lower mortality rates following EVAR than male octogenarians (adjusted OR=0.7, 95% CI=0.6–0.8). Conclusion: Based on this nationwide study with real-world registry data, mortality rates of octogenarians following ruptured AAA-repair were high, especially after OSR. However, a substantial proportion of these octogenarians following OSR and EVAR had an uneventful recovery. Known preoperative factors do influence perioperative outcomes and reflect current treatment practice.

Published
2022

31. Optimization of Preoperative Lymph Node Staging in Patients with Muscle-Invasive Bladder Cancer Using Radiomics on Computed Tomography

Author

Starmans, Martijn P.A., Ho, Li Shen, Smits, Fokko, Beije, Nick, de Kruijff, Inge, de Jong, Joep J., Somford, Diederik M., Boevé, Egbert R., Te Slaa, Ed, Cauberg, Evelyne C.C., Klaver, Sjoerd, van der Heijden, Antoine G., Wijburg, Carl J., van de Luijtgaarden, Addy C.M., van Melick, Harm H.E., Cauffman, Ella, de Vries, Peter, Jacobs, Rens, Niessen, Wiro J., Visser, Jacob J., Klein, Stefan, Boormans, Joost L., van der Veldt, Astrid A.M., Starmans, Martijn P.A., Ho, Li Shen, Smits, Fokko, Beije, Nick, de Kruijff, Inge, de Jong, Joep J., Somford, Diederik M., Boevé, Egbert R., Te Slaa, Ed, Cauberg, Evelyne C.C., Klaver, Sjoerd, van der Heijden, Antoine G., Wijburg, Carl J., van de Luijtgaarden, Addy C.M., van Melick, Harm H.E., Cauffman, Ella, de Vries, Peter, Jacobs, Rens, Niessen, Wiro J., Visser, Jacob J., Klein, Stefan, Boormans, Joost L., and van der Veldt, Astrid A.M.

Abstract

Approximately 25% of the patients with muscle-invasive bladder cancer (MIBC) who are clinically node negative have occult lymph node metastases at radical cystectomy (RC) and pelvic lymph node dissection. The aim of this study was to evaluate preoperative CT-based radiomics to differentiate between pN+ and pN0 disease in patients with clinical stage cT2-T4aN0-N1M0 MIBC. Patients with cT2-T4aN0-N1M0 MIBC, of whom preoperative CT scans and pathology reports were available, were included from the prospective, multicenter CirGuidance trial. After manual segmentation of the lymph nodes, 564 radiomics features were extracted. A combination of different machine-learning methods was used to develop various decision models to differentiate between patients with pN+ and pN0 disease. A total of 209 patients (159 pN0; 50 pN+) were included, with a total of 3153 segmented lymph nodes. None of the individual radiomics features showed significant differences between pN+ and pN0 disease, and none of the radiomics models performed substantially better than random guessing. Hence, CT-based radiomics does not contribute to differentiation between pN+ and pN0 disease in patients with cT2-T4aN0-N1M0 MIBC.

Published
2022

32. Optimization of Preoperative Lymph Node Staging in Patients with Muscle-Invasive Bladder Cancer Using Radiomics on Computed Tomography

Author

Starmans, Martijn P. A., primary, Ho, Li Shen, additional, Smits, Fokko, additional, Beije, Nick, additional, de Kruijff, Inge, additional, de Jong, Joep J., additional, Somford, Diederik M., additional, Boevé, Egbert R., additional, te Slaa, Ed, additional, Cauberg, Evelyne C. C., additional, Klaver, Sjoerd, additional, van der Heijden, Antoine G., additional, Wijburg, Carl J., additional, van de Luijtgaarden, Addy C. M., additional, van Melick, Harm H. E., additional, Cauffman, Ella, additional, de Vries, Peter, additional, Jacobs, Rens, additional, Niessen, Wiro J., additional, Visser, Jacob J., additional, Klein, Stefan, additional, Boormans, Joost L., additional, and van der Veldt, Astrid A. M., additional

Published
2022
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33. Optimization of Preoperative Lymph Node Staging in Patients with Muscle-Invasive Bladder Cancer Using Radiomics on Computed Tomography

Author

Martijn P. A. Starmans, Li Shen Ho, Fokko Smits, Nick Beije, Inge de Kruijff, Joep J. de Jong, Diederik M. Somford, Egbert R. Boevé, Ed te Slaa, Evelyne C. C. Cauberg, Sjoerd Klaver, Antoine G. van der Heijden, Carl J. Wijburg, Addy C. M. van de Luijtgaarden, Harm H. E. van Melick, Ella Cauffman, Peter de Vries, Rens Jacobs, Wiro J. Niessen, Jacob J. Visser, Stefan Klein, Joost L. Boormans, Astrid A. M. van der Veldt, Radiology & Nuclear Medicine, Medical Oncology, and Urology

Subjects
All institutes and research themes of the Radboud University Medical Center, SDG 3 - Good Health and Well-being, bladder cancer, computed tomography, machine learning, radiomics, Urological cancers Radboud Institute for Molecular Life Sciences [Radboudumc 15], Medicine (miscellaneous)
Abstract

Approximately 25% of the patients with muscle-invasive bladder cancer (MIBC) who are clinically node negative have occult lymph node metastases at radical cystectomy (RC) and pelvic lymph node dissection. The aim of this study was to evaluate preoperative CT-based radiomics to differentiate between pN+ and pN0 disease in patients with clinical stage cT2-T4aN0-N1M0 MIBC. Patients with cT2-T4aN0-N1M0 MIBC, of whom preoperative CT scans and pathology reports were available, were included from the prospective, multicenter CirGuidance trial. After manual segmentation of the lymph nodes, 564 radiomics features were extracted. A combination of different machine-learning methods was used to develop various decision models to differentiate between patients with pN+ and pN0 disease. A total of 209 patients (159 pN0; 50 pN+) were included, with a total of 3153 segmented lymph nodes. None of the individual radiomics features showed significant differences between pN+ and pN0 disease, and none of the radiomics models performed substantially better than random guessing. Hence, CT-based radiomics does not contribute to differentiation between pN+ and pN0 disease in patients with cT2-T4aN0-N1M0 MIBC.

Published
2022

36. Three-Dimensional Optical Scanning in Post-kala-azar Dermal Leishmaniasis (PKDL)

Author

Jan Wolff, Eduard E. Zijlstra, Sjoerd te Slaa, Niels P.T.J. Liberton, Ahmed Eleojo Musa, and Oral and Maxillofacial Surgery / Oral Pathology

Subjects
Male, medicine.medical_specialty, 030231 tropical medicine, Leishmaniasis, Cutaneous, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Virology, medicine, Humans, Skin, Post-kala-azar dermal leishmaniasis, integumentary system, business.industry, Optical Imaging, Leishmaniasis, Articles, medicine.disease, Optical scanning, Dermatology, Infectious Diseases, Visceral leishmaniasis, Leishmaniasis, Visceral, Parasitology, business, Skin lesion
Abstract

Post–kala-azar dermal leishmaniasis may occur after successful treatment of visceral leishmaniasis and is characterized by macules, papules, or nodules in the skin, with varying size. The response to antileishmanial therapy remains difficult to assess because there are presently no reliable biomarkers. To date, skin lesions are clinically assessed for decrease in size or change in color, which is invariably subjective. Novel 3-dimensional optical scanning devices offer safe and field-adapted methods to objectively assess skin lesions for changes over time in size and color that can be quantified with great accuracy.

Published
2020
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37. Toward Optimizing Risk Adjustment in the Dutch Surgical Aneurysm Audit

Author

Niki Lijftogt, Anco Vahl, Esmee M. van der Willik, Vanessa J. Leijdekkers, Michel W.J.M. Wouters, Jaap F. Hamming, L.H. Van den Akker, P.J. Van den Akker, G.J. Akkersdijk, G.P. Akkersdijk, W.L. Akkersdijk, M.G. van Andringa de Kempenaer, C.H. Arts, J.A. Avontuur, J.G. Baal, O.J. Bakker, R. Balm, W.B. Barendregt, M.H. Bender, B.L. Bendermacher, M. van den Berg, P. Berger, R.J. Beuk, J.D. Blankensteijn, R.J. Bleker, J.H. Bockel, M.E. Bodegom, K.E. Bogt, A.P. Boll, M.H. Booster, B.L. Borger van der Burg, G.J. de Borst, W.T. Bos-van Rossum, J. Bosma, J.M. Botman, L.H. Bouwman, J.C. Breek, V. Brehm, M.J. Brinckman, T.H. van den Broek, H.L. Brom, M.T. de Bruijn, J.L. de Bruin, P. Brummel, J.P. van Brussel, S.E. Buijk, M.G. Buimer, D.H. Burger, H.C. Buscher, G. den Butter, E. Cancrinus, P.H. Castenmiller, G. Cazander, H.M. Coveliers, P.H. Cuypers, J.H. Daemen, I. Dawson, A.F. Derom, A.R. Dijkema, J. Diks, M.K. Dinkelman, M. Dirven, D.E. Dolmans, R.C. van Doorn, L.M. van Dortmont, M.M. van der Eb, D. Eefting, G.J. van Eijck, J.W. Elshof, B.H. Elsman, A. van der Elst, M.I. van Engeland, R.G. van Eps, M.J. Faber, W.M. de Fijter, B. Fioole, W.M. Fritschy, R.H. Geelkerken, W.B. van Gent, G.J. Glade, B. Govaert, R.P. Groenendijk, H.G. de Groot, R.F. van den Haak, E.F. de Haan, G.F. Hajer, J.F. Hamming, E.S. van Hattum, C.E. Hazenberg, P.P. Hedeman Joosten, J.N. Helleman, L.G. van der Hem, J.M. Hendriks, J.A. van Herwaarden, J.M. Heyligers, J.W. Hinnen, R.J. Hissink, Ho GH, P.T. den Hoed, M.T. Hoedt, F. van Hoek, R. Hoencamp, W.H. Hoffmann, A.W. Hoksbergen, E.J. Hollander, L.C. Huisman, R.G. Hulsebos, K.M. Huntjens, M.M. Idu, M.J. Jacobs, M.F. van der Jagt, J.R. Jansbeken, R.J. Janssen, H.H. Jiang, S.C. de Jong, V. Jongkind, M.R. Kapma, B.P. Keller, A. Khodadade Jahrome, J.K. Kievit, P.L. Klemm, P. Klinkert, B. Knippenberg, N.A. Koedam, M.J. Koelemaij, J.L. Kolkert, G.G. Koning, O.H. Koning, A.G. Krasznai, R.M. Krol, R.H. Kropman, R.R. Kruse, L. van der Laan, M.J. van der Laan, J.H. van Laanen, J.H. Lardenoye, J.A. Lawson, D.A. Legemate, V.J. Leijdekkers, M.S. Lemson, M.M. Lensvelt, M.A. Lijkwan, R.C. Lind, F.T. van der Linden, P.F. Liqui Lung, M.J. Loos, M.C. Loubert, D.E. Mahmoud, C.G. Manshanden, E.C. Mattens, R. Meerwaldt, B.M. Mees, R. Metz, R.C. Minnee, J.C. de Mol van Otterloo, F.L. Moll, Y.C. Montauban van Swijndregt, M.J. Morak, R.H. van de Mortel, W. Mulder, S.K. Nagesser, C.C. Naves, J.H. Nederhoed, A.M. Nevenzel-Putters, A.J. de Nie, D.H. Nieuwenhuis, J. Nieuwenhuizen, R.C. van Nieuwenhuizen, D. Nio, A.P. Oomen, B.I. Oranen, J. Oskam, H.W. Palamba, A.G. Peppelenbosch, A.S. van Petersen, T.F. Peterson, B.J. Petri, M.E. Pierie, A.J. Ploeg, R.A. Pol, E.D. Ponfoort, P.P. Poyck, A. Prent, S. ten Raa, J.T. Raymakers, M. Reichart, B.L. Reichmann, M.M. Reijnen, A. Rijbroek, M.J. van Rijn, R.A. de Roo, E.V. Rouwet, C.G. Rupert, B.R. Saleem, M.R. van Sambeek, M.G. Samyn, H.P. van 't Sant, J. van Schaik, P.M. van Schaik, D.M. Scharn, M.R. Scheltinga, A. Schepers, P.M. Schlejen, F.J. Schlosser, F.P. Schol, O. Schouten, M.H. Schreinemacher, M.A. Schreve, G.W. Schurink, C.J. Sikkink, M.P. Siroen, A. te Slaa, H.J. Smeets, L. Smeets, A.A. de Smet, P. de Smit, P.C. Smit, T.M. Smits, M.G. Snoeijs, A.O. Sondakh, T.J. van der Steenhoven, S.M. van Sterkenburg, D.A. Stigter, H. Stigter, R.P. Strating, G.N. Stultiëns, J.E. Sybrandy, J.A. Teijink, B.J. Telgenkamp, M.J. Testroote, R.M. The, W.J. Thijsse, I.F. Tielliu, R.B. van Tongeren, R.J. Toorop, J.H. Tordoir, E. Tournoij, M. Truijers, K. Türkcan, R.P. Tutein Nolthenius, Ç. Ünlü, A.A. Vafi, A.C. Vahl, E.J. Veen, H.T. Veger, M.G. Veldman, H.J. Verhagen, B.A. Verhoeven, C.F. Vermeulen, E.G. Vermeulen, B.P. Vierhout, M.J. Visser, J.A. van der Vliet, C.J. Vlijmen - van Keulen, H.G. Voesten, R. Voorhoeve, A.W. Vos, B. de Vos, G.A. Vos, B.H. Vriens, Vriens PW, A.C. de Vries, J.P. de Vries, M. de Vries, C. van der Waal, E.J. Waasdorp, B.M. Wallis de Vries, L.A. van Walraven, J.L. van Wanroij, M.C. Warlé, V. van Weel, A.M. van Well, G.M. Welten, R.J. Welten, J.J. Wever, A.M. Wiersema, O.R. Wikkeling, W.I. Willaert, J. Wille, M.C. Willems, E.M. Willigendael, W. Wisselink, M.E. Witte, C.H. Wittens, I.C. Wolf-de Jonge, O. Yazar, C.J. Zeebregts, M.L. van Zeeland, Surgery, ACS - Atherosclerosis & ischemic syndromes, Multi-Modality Medical Imaging, Gastroenterology and hepatology, Pediatrics, Hematology laboratory, Obstetrics and gynaecology, Amsterdam Movement Sciences - Restoration and Development, Public and occupational health, AGEM - Digestive immunity, Amsterdam Reproduction & Development (AR&D), ACS - Microcirculation, ACS - Diabetes & metabolism, RS: CAPHRI - R5 - Optimising Patient Care, and Epidemiologie

Subjects
Male, medicine.medical_specialty, Time Factors, SURGERY, Aortic Rupture, UT-Hybrid-D, 030204 cardiovascular system & hematology, Logistic regression, Risk Assessment, Decision Support Techniques, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Predictive Value of Tests, Risk Factors, Electronic Health Records, Humans, Medicine, Prospective Studies, Registries, Prospective cohort study, Aged, Netherlands, Aged, 80 and over, ABDOMINAL AORTIC-ANEURYSM, Medical Audit, business.industry, MORTALITY, Glasgow Coma Scale, Reproducibility of Results, General Medicine, medicine.disease, Comorbidity, Abdominal aortic aneurysm, n/a OA procedure, ERA, MODEL, Treatment Outcome, Predictive value of tests, Emergency medicine, Female, Cardiology and Cardiovascular Medicine, business, Risk assessment, Vascular Surgical Procedures, Aortic Aneurysm, Abdominal, Abdominal surgery
Abstract

Background: To compare hospital outcomes of aortic aneurysm surgery, casemix correction for preoperative variables is essential. Most of these variables can be deduced from mortality risk prediction models. Our aim was to identify the optimal set of preoperative variables associated with mortality to establish a relevant and efficient casemix model.Methods: All patients prospectively registered between 2013 and 2016 in the Dutch Surgical Aneurysm Audit (DSAA) were included for the analysis. After multiple imputation for missing variables, predictors for mortality following univariable logistic regression were analyzed in a manual backward multivariable logistic regression model and compared with three standard mortality risk prediction models: Glasgow Aneurysm Score (GAS, mainly clinical parameters), Vascular Biochemical and Haematological Outcome Model (VBHOM, mainly laboratory parameters), and Dutch Aneurysm Score (DAS, both clinical and laboratory parameters). Discrimination and calibration were tested and considered good with a C-statistic > 0.8 and Hosmer-Lemeshow (H-L) P > 0.05.Results: There were 12,401 patients: 9,537 (76.9%) elective patients (EAAA), 913 (7.4%) acute symptomatic patients (SAAA), and 1,951 (15.7%) patients with acute rupture (RAAA). Overall postoperative mortality was 6.5%; 1.8% after EAAA surgery, 6.6% after SAAA, and 29.6% after RAAA surgery. The optimal set of independent variables associated with mortality was a mix of clinical and laboratory parameters: gender, age, pulmonary comorbidity, operative setting, creatinine, aneurysm size, hemoglobin, Glasgow coma scale, electrocardiography, and systolic blood pressure (C-statistic 0.871). External validation overall of VBHOM, DAS, and GAS revealed C-statistics of 0.836, 0.782, and 0.761, with an H-L of 0.028, 0.00, and 0.128, respectively.Conclusions: The optimal set of variables for casemix correction in the DSAA comprises both clinical and laboratory parameters, which can be collected easily from electronic patient files and will lead to an efficient casemix model.

Published
2019
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42. Nationwide Study to Predict Colonic Ischemia after Abdominal Aortic Aneurysm Repair in The Netherlands

Author

Saskia Irene Willemsen, Martijn Geert ten Berge, Randolph George Statius van Eps, Hugo Thomas Christian Veger, Hans van Overhagen, Lukas Carolus van Dijk, Hein Putter, Jan Jacob Wever, L.H. Van den Akker, P.J. Van den Akker, G.J. Akkersdijk, G.P. Akkersdijk, W.L. Akkersdijk, M.G. van Andringa de Kempenaer, C.H. Arts, J.A. Avontuur, J.G. Baal, O.J. Bakker, R. Balm, W.B. Barendregt, M.H. Bender, B.L. Bendermacher, M. van den Berg, P. Berger, R.J. Beuk, J.D. Blankensteijn, R.J. Bleker, J.H. Bockel, M.E. Bodegom, K.E. Bogt, A.P. Boll, M.H. Booster, B.L. Borger van der Burg, G.J. de Borst, W.T. Bos-van Rossum, J. Bosma, J.M. Botman, L.H. Bouwman, J.C. Breek, V. Brehm, M.J. Brinckman, T.H. van den Broek, H.L. Brom, M.T. de Bruijn, J.L. de Bruin, P. Brummel, J.P. van Brussel, S.E. Buijk, M.G. Buimer, D.H. Burger, H.C. Buscher, G. den Butter, E. Cancrinus, P.H. Castenmiller, G. Cazander, H.M. Coveliers, P.H. Cuypers, J.H. Daemen, I. Dawson, A.F. Derom, A.R. Dijkema, J. Diks, M.K. Dinkelman, M. Dirven, D.E. Dolmans, R.C. van Doorn, L.M. van Dortmont, M.M. van der Eb, D. Eefting, G.J. van Eijck, J.W. Elshof, B.H. Elsman, A. van der Elst, M.I. van Engeland, R.G. van Eps, M.J. Faber, W.M. de Fijter, B. Fioole, W.M. Fritschy, R.H. Geelkerken, W.B. van Gent, G.J. Glade, B. Govaert, R.P. Groenendijk, H.G. de Groot, R.F. van den Haak, E.F. de Haan, G.F. Hajer, J.F. Hamming, E.S. van Hattum, C.E. Hazenberg, P.P. Hedeman Joosten, J.N. Helleman, L.G. van der Hem, J.M. Hendriks, J.A. van Herwaarden, J.M. Heyligers, J.W. Hinnen, R.J. Hissink, G.H. Ho, P.T. den Hoed, M.T. Hoedt, F. van Hoek, R. Hoencamp, W.H. Hoffmann, A.W. Hoksbergen, E.J. Hollander, L.C. Huisman, R.G. Hulsebos, K.M. Huntjens, M.M. Idu, M.J. Jacobs, M.F. van der Jagt, J.R. Jansbeken, R.J. Janssen, H.H. Jiang, S.C. de Jong, V. Jongkind, M.R. Kapma, B.P. Keller, A. Khodadade Jahrome, J.K. Kievit, P.L. Klemm, P. Klinkert, B. Knippenberg, N.A. Koedam, M.J. Koelemaij, J.L. Kolkert, G.G. Koning, O.H. Koning, A.G. Krasznai, R.M. Krol, R.H. Kropman, R.R. Kruse, L. van der Laan, M.J. van der Laan, J.H. van Laanen, J.H. Lardenoye, J.A. Lawson, D.A. Legemate, V.J. Leijdekkers, M.S. Lemson, M.M. Lensvelt, M.A. Lijkwan, R.C. Lind, F.T. van der Linden, P.F. Liqui Lung, M.J. Loos, M.C. Loubert, D.E. Mahmoud, C.G. Manshanden, E.C. Mattens, R. Meerwaldt, B.M. Mees, R. Metz, R.C. Minnee, J.C. de Mol van Otterloo, F.L. Moll, Y.C. Montauban van Swijndregt, M.J. Morak, R.H. van de Mortel, W. Mulder, S.K. Nagesser, C.C. Naves, J.H. Nederhoed, A.M. Nevenzel-Putters, A.J. de Nie, D.H. Nieuwenhuis, J. Nieuwenhuizen, R.C. van Nieuwenhuizen, D. Nio, A.P. Oomen, B.I. Oranen, J. Oskam, H.W. Palamba, A.G. Peppelenbosch, A.S. van Petersen, T.F. Peterson, B.J. Petri, M.E. Pierie, A.J. Ploeg, R.A. Pol, E.D. Ponfoort, P.P. Poyck, A. Prent, S. ten Raa, J.T. Raymakers, M. Reichart, B.L. Reichmann, M.M. Reijnen, A. Rijbroek, M.J. van Rijn, R.A. de Roo, E.V. Rouwet, C.G. Rupert, B.R. Saleem, M.R. van Sambeek, M.G. Samyn, H.P. van’t Sant, J. van Schaik, P.M. van Schaik, D.M. Scharn, M.R. Scheltinga, A. Schepers, P.M. Schlejen, F.J. Schlosser, F.P. Schol, O. Schouten, M.H. Schreinemacher, M.A. Schreve, G.W. Schurink, C.J. Sikkink, M.P. Siroen, A. te Slaa, H.J. Smeets, L. Smeets, A.A. de Smet, P. de Smit, P.C. Smit, T.M. Smits, M.G. Snoeijs, A.O. Sondakh, T.J. van der Steenhoven, S.M. van Sterkenburg, D.A. Stigter, H. Stigter, R.P. Strating, G.N. Stultiëns, J.E. Sybrandy, J.A. Teijink, B.J. Telgenkamp, M.J. Testroote, R.M. The, W.J. Thijsse, I.F. Tielliu, R.B. van Tongeren, R.J. Toorop, J.H. Tordoir, E. Tournoij, M. Truijers, K. Türkcan, R.P. Tutein Nolthenius, Ç. Ünlü, A.A. Vafi, A.C. Vahl, E.J. Veen, H.T. Veger, M.G. Veldman, H.J. Verhagen, B.A. Verhoeven, C.F. Vermeulen, E.G. Vermeulen, B.P. Vierhout, M.J. Visser, J.A. van der Vliet, C.J. Vlijmen-van Keulen, H.G. Voesten, R. Voorhoeve, A.W. Vos, B. de Vos, G.A. Vos, B.H. Vriens, P.W. Vriens, A.C. de Vries, J.P. de Vries, M. de Vries, C. van der Waal, E.J. Waasdorp, B.M. Wallis de Vries, L.A. van Walraven, J.L. van Wanroij, M.C. Warlé, V. van Weel, A.M. van Well, G.M. Welten, R.J. Welten, J.J. Wever, A.M. Wiersema, O.R. Wikkeling, W.I. Willaert, J. Wille, M.C. Willems, E.M. Willigendael, W. Wisselink, M.E. Witte, C.H. Wittens, I.C. Wolf-de Jonge, O. Yazar, C.J. Zeebregts, M.L. van Zeeland, TechMed Centre, Multi-Modality Medical Imaging, Technical Medicine, Surgery, ACS - Atherosclerosis & ischemic syndromes, Medical Biochemistry, ACS - Diabetes & metabolism, Amsterdam Gastroenterology Endocrinology Metabolism, APH - Methodology, and APH - Quality of Care

Subjects
Male, Time Factors, medicine.medical_treatment, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], 030204 cardiovascular system & hematology, Logistic regression, Endovascular aneurysm repair, 030218 nuclear medicine & medical imaging, 0302 clinical medicine, Risk Factors, Colon/blood supply, 80 and over, Medicine, Aortic Aneurysm, Abdominal/surgery, Netherlands, Aged, 80 and over, Univariate analysis, education.field_of_study, Endovascular Procedures, General Medicine, Middle Aged, Abdominal aortic aneurysm, Aortic Aneurysm, Treatment Outcome, Elective Surgical Procedures, Cardiology, Female, Cardiology and Cardiovascular Medicine, Cohort study, medicine.medical_specialty, Colon, Population, Mesenteric Ischemia/diagnosis, Risk Assessment, 03 medical and health sciences, Blood Vessel Prosthesis Implantation, Aneurysm, Internal medicine, Humans, Endovascular Procedures/adverse effects, cardiovascular diseases, Blood Vessel Prosthesis Implantation/adverse effects, education, Aged, Retrospective Studies, business.industry, Colonic ischemia, Abdominal/surgery, medicine.disease, Mesenteric Ischemia, Surgery, Emergencies, business, Aortic Aneurysm, Abdominal
Abstract

BACKGROUND: Colonic ischemia remains a severe complication after abdominal aortic aneurysm (AAA) repair and is associated with a high mortality. With open repair being one of the main risk factors of colonic ischemia, deciding between endovascular or open aneurysm repair should be based on tailor-made medicine. This study aims to identify high-risk patients of colonic ischemia, a risk that can be taken into account while deciding on AAA treatment strategy.METHODS: A nationwide population-based cohort study of 9,433 patients who underwent an AAA operation between 2014 and 2016 was conducted. Potential risk factors were determined by reviewing prior studies and univariate analysis. With logistic regression analysis, independent predictors of intestinal ischemia were established. These variables were used to form a prediction model.RESULTS: Intestinal ischemia occurred in 267 patients (2.8%). Occurrence of intestinal ischemia was seen significantly more in open repair versus endovascular aneurysm repair (7.6% vs. 0.9%; P < 0.001). This difference remained significant after stratification by urgency of the procedure, in both intact open (4.2% vs. 0.4%; P < 0.001) and ruptured open repair (15.0% vs. 6.2%); P < 0.001). Rupture of the AAA was the most important predictor of developing intestinal ischemia (odds ratio [OR], 5.9, 95% confidence interval [CI] 4.4-8.0), followed by having a suprarenal AAA (OR 3.4; CI 1.1-10.6). Associated procedural factors were open repair (OR 2.8; 95% CI 1.9-4.2), blood loss >1L (OR 3.6; 95% CI 1.7-7.5), and prolonged operating time (OR 2.0; 95% CI 1.4-2.8). Patient characteristics included having peripheral arterial disease (OR 2.4; 95% CI 1.3-4.4), female gender (OR 1.7; 95% CI 1.2-2.4), renal insufficiency (OR 1.7; 1.3-2.2), and pulmonary history (OR 1.6; 95% CI 1.2-2.2). Age CONCLUSIONS: One of the main risk factors is open repair. Several other risk factors can contribute to developing colonic ischemia after AAA repair. The proposed prediction model can be used to identify patients at high risk for developing colonic ischemia. With the current trend in AAA repair leaning toward open repair for better long-term results, our prediction model allows a better informed decision can be made in AAA treatment strategy.

Published
2021

43. Robot-assisted Versus Open Radical Cystectomy in Bladder Cancer: An Economic Evaluation Alongside a Multicentre Comparative Effectiveness Study

Author

Charlotte T.J. Michels, Carl J. Wijburg, Gerjon Hannink, J. Alfred Witjes, Maroeska M. Rovers, Janneke P.C. Grutters, Sip Helder, Guus Venderbosch, Hilly Calsbeek, Ilze E.W.van Onna, Evert J. Barten, Evert L. Koldewijn, Joost L. Boormans, Bart P. Wijsman, Ronald I. Nooter, Peter J. Zwaan, Ed te Slaa, Saskia van der Meer, Sjoerd O. Klaver, Laurent M.C.L. Fossion, Siebe D. Bos, Harm H.E.van Melick, Anna M. Leliveld, Richard P. Meijer, André N. Vis, Gerard J. Molijn, Chris L. Berendsen, Jorg R. Oddens, Urology, and CCA - Imaging and biomarkers

Subjects
medicine.medical_specialty, Complications, Cost effectiveness, Cost-Benefit Analysis, Urology, medicine.medical_treatment, Urinary Bladder, 030232 urology & nephrology, Quality-adjusted life year, Cystectomy, 03 medical and health sciences, Postoperative Complications, 0302 clinical medicine, Internal medicine, Urological cancers Radboud Institute for Molecular Life Sciences [Radboudumc 15], Humans, Medicine, Prospective Studies, Imputation (statistics), Bladder cancer, business.industry, Standard treatment, Other Research Radboud Institute for Health Sciences [Radboudumc 0], Robotics, medicine.disease, Confidence interval, Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10], Radical cystectomy, Treatment Outcome, Urinary Bladder Neoplasms, Urological cancers Radboud Institute for Health Sciences [Radboudumc 15], 030220 oncology & carcinogenesis, Economic evaluation, Cost-effectiveness, Economic Evaluation, business
Abstract

Background Open radical cystectomy (ORC) is regarded as the standard treatment for muscle-invasive bladder cancer, but robot-assisted radical cystectomy (RARC) is increasingly used in practice. A recent study showed that RARC resulted in slightly fewer minor but slightly more major complications, although the difference was not statistically significant. Some differences were found in secondary outcomes favouring either RARC or ORC. RARC use is expected to increase in coming years, which fuels the debate about whether RARC provides value for money. Objective To assess the cost-effectiveness of RARC compared to ORC in bladder cancer. Design, setting, and participants This economic evaluation was performed alongside a prospective multicentre comparative effectiveness study. We included 348 bladder cancer patients (ORC, n = 168; RARC, n = 180) from 19 Dutch hospitals. Outcome measurements and statistical analysis Over 1 yr, we assessed the incremental cost per quality-adjusted life year (QALY) gained from both healthcare and societal perspectives. We used single imputation nested in the bootstrap percentile method to assess missing data and uncertainty, and inverse probability of treatment weighting to control for potential bias. Deterministic sensitivity analyses were performed to explore the impact of various parameters on the cost difference. Results and limitations The mean healthcare cost per patient was €17 141 (95% confidence interval [CI] €15 791–€18 720) for ORC and €21 266 (95% CI €19 163–€23 650) for RARC. The mean societal cost per patient was €18 926 (95% CI €17 431–€22 642) for ORC and €24 896 (95% CI €21 925–€31 888) for RARC. On average, RARC patients gained 0.79 QALYs (95% CI 0.74–0.85) compared to 0.81 QALYs (95% CI 0.77–0.85) for ORC patients, resulting in a mean QALY difference of −0.02 (95% CI −0.05 to 0.02). Using a cost-effectiveness threshold of €80 000, RARC was cost-effective in 0.6% and 0.2% of the replications for the healthcare and societal perspectives, respectively. Conclusions RARC shows no difference in terms of QALYs, but is more expensive than ORC. Hence, RARC does not seem to provide value for money in comparison to ORC. Patient summary This study assessed the relation between costs and effects of robot-assisted surgery compared to open surgery for removal of the bladder in 348 Dutch patients with bladder cancer. We found that after 1 year, the two approaches were similarly effective according to a measure called quality-adjusted life years, but robot-assisted surgery was much more expensive. This trial was prospectively registered in the Netherlands Trial Register as NTR5362 ( https://www.trialregister.nl/trial/5214 ).

Published
2021
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44. Robot-assisted Radical Cystectomy Versus Open Radical Cystectomy in Bladder Cancer Patients: A Multicentre Comparative Effectiveness Study

Author

Carl J. Wijburg, Charlotte T.J. Michels, Gerjon Hannink, Janneke P.C. Grutters, Maroeska M. Rovers, J. Alfred Witjes, Ilze E.W. van Onna, Evert J. Barten, Evert L. Koldewijn, Joost L. Boormans, Bart P. Wijsman, Ronald I. Nooter, Peter J. Zwaan, Ed te Slaa, Saskia van der Meer, Sjoerd O. Klaver, Laurent M.C.L. Fossion, Siebe D. Bos, Harm H.E.van Melick, Anna M. Leliveld, Richard P. Meijer, André N. Vis, Gerard J. Molijn, Chris L. Berendsen, and Jorg R. Oddens

Subjects
Robot assisted, medicine.medical_specialty, Complications, Urology, medicine.medical_treatment, 030232 urology & nephrology, Effectiveness, Cystectomy, 03 medical and health sciences, All institutes and research themes of the Radboud University Medical Center, Postoperative Complications, 0302 clinical medicine, Robotic Surgical Procedures, Quality of life, Urological cancers Radboud Institute for Molecular Life Sciences [Radboudumc 15], medicine, Humans, Prospective Studies, Bladder cancer, business.industry, Standard treatment, Urinary diversion, Robotics, Perioperative, medicine.disease, Confidence interval, Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10], Radical cystectomy, Treatment Outcome, Urinary Bladder Neoplasms, Urological cancers Radboud Institute for Health Sciences [Radboudumc 15], 030220 oncology & carcinogenesis, Propensity score matching, Quality of Life, business
Abstract

Background: Radical cystectomy with pelvic lymph node dissection (PLND) and urinary diversion in patients with bladder cancer is known for its high risk of complications. Although open radical cystectomy (ORC) is regarded as the standard treatment, robot-assisted radical cystectomy (RARC) is increasingly used in practice, despite the fact that high-quality evidence comparing the effectiveness of both techniques is lacking.Objective: To study the effectiveness of RARC compared with that of ORC, in terms of 90 d complications (Clavien-Dindo), health-related quality of life (HRQOL), and clinical outcomes.Design, setting, and participants: A prospective comparative effectiveness study was conducted in 19 Dutch centres, expert in either ORC or RARC. Follow-up visits were scheduled at 30, 90, and 365 d.Intervention: Standard ORC or RARC with PLND, using a standardised perioperative protocol. Outcome measurements and statistical analysis: The primary outcome was any-grade complications after 90 d. Secondary outcomes included HRQOL, complications (minor, major, 30 d, and 365 d), and clinical outcomes. Differences were calculated as risk differences (RDs) between the groups with 95% confidence intervals (CIs), adjusted for potential baseline differences by means of propensity score–based inverse probability of treatment weighting.Results and limitations: Between March 2016 and November 2018, 348 patients were included (n = 168 for ORC, n = 180 for RARC). At 90 d, any-grade complication rates were 63% for ORC and 56% for RARC (RD –6.4%, 95% CI –17 to 4.5). Major complication rates were 15% for ORC and 16% for RARC (RD 0.9%, 95% CI –7.0 to 8.8). Total minor complication rates were 57% for ORC and 49% for RARC (RD –7.6%, 95% CI –19 to 3.6). Analyses showed no statistically significant differences in HRQOL between ORC and RARC. Some differences were found in the secondary outcomes in favour of either RARC or ORC. The major drawback inherent to the design comprises residual confounding.Conclusions: This multicentre comparative effectiveness study showed no statistically significant differences between ORC and RARC in terms of complications and HRQOL.Patient summary: This multicentre study did not show differences in overall complication rates, health-related quality of life, mortality, and clinical and oncological outcomes between open and robot-assisted radical cystectomy in bladder cancer patients.

Published
2021

45. Outcomes in Octogenarians and the Effect of Comorbidities After Intact Abdominal Aortic Aneurysm Repair in the Netherlands: A Nationwide Cohort Study

Author

Alberga, Anna J., primary, Karthaus, Eleonora G., additional, van Zwet, Erik W., additional, de Bruin, Jorg L., additional, van Herwaarden, Joost A., additional, Wever, Jan J., additional, Verhagen, Hence J.M., additional, Van den Akker, P.J., additional, Akkersdijk, G.J., additional, Akkersdijk, G.P., additional, Akkersdijk, W.L., additional, van Andringa de Kempenaer, M.G., additional, Arts, C.H., additional, Avontuur, J.A., additional, Bakker, O.J., additional, Balm, R., additional, Barendregt, W.B., additional, Bekken, J.A., additional, Bender, M.H., additional, Bendermacher, B.L., additional, van den Berg, M., additional, Berger, P., additional, Beuk, R.J., additional, Blankensteijn, J.D., additional, Bleker, R.J., additional, Blok, J.J., additional, Bode, A.S., additional, Bodegom, M.E., additional, van der Bogt, K.E., additional, Boll, A.P., additional, Booster, M.H., additional, Borger van der Burg, B.L., additional, de Borst, G.J., additional, Bos- van Rossum, W.T., additional, Bosma, J., additional, Botman, J.M., additional, Bouwman, L.H., additional, Brehm, V., additional, de Bruijn, M.T., additional, de Bruin, J.L., additional, Brummel, P., additional, van Brussel, J.P., additional, Buijk, S.E., additional, Buijs, M.A., additional, Buimer, M.G., additional, Burger, D.H., additional, Buscher, H.C., additional, Cancrinus, E., additional, Castenmiller, P.H., additional, Cazander, G., additional, Coester, A.M., additional, Cuypers, P.H., additional, Daemen, J.H., additional, Dawson, I., additional, Dierikx, J.E., additional, Dijkstra, M.L., additional, Diks, J., additional, Dinkelman, M.K., additional, Dirven, M., additional, Dolmans, D.E., additional, van Doorn, R.C., additional, van Dortmont, L.M., additional, Drouven, J.W., additional, van der Eb, M.M., additional, Eefting, D., additional, van Eijck, G.J., additional, Elshof, J.W., additional, Elsman, B.H., additional, van der Elst, A., additional, van Engeland, M.I., additional, van Eps, R.G., additional, Faber, M.J., additional, de Fijter, W.M., additional, Fioole, B., additional, Fokkema, T.M., additional, Frans, F.A., additional, Fritschy, W.M., additional, Fung Kon Jin, P.H., additional, Geelkerken, R.H., additional, van Gent, W.B., additional, Glade, G.J., additional, Govaert, B., additional, Groenendijk, R.P., additional, de Groot, H.G., additional, van den Haak, R.F., additional, de Haan, E.F., additional, Hajer, G.F., additional, Hamming, J.F., additional, van Hattum, E.S., additional, Hazenberg, C.E., additional, Hedeman Joosten, P.P., additional, Helleman, J.N., additional, van der Hem, L.G., additional, Hendriks, J.M., additional, van Herwaarden, J.A., additional, Heyligers, J.M., additional, Hinnen, J.W., additional, Hissink, R.J., additional, Ho, G.H., additional, den Hoed, P.T., additional, Hoedt, M.T., additional, van Hoek, F., additional, Hoencamp, R., additional, Hoffmann, W.H., additional, Hogendoorn, W., additional, Hoksbergen, A.W., additional, Hollander, E.J., additional, Hommes, M., additional, Hopmans, C.J., additional, Huisman, L.C., additional, Hulsebos, R.G., additional, Huntjens, K.M., additional, Idu, M.M., additional, Jacobs, M.J., additional, van der Jagt, M.F., additional, Jansbeken, J.R., additional, Janssen, R.J., additional, Jiang, H.H., additional, de Jong, S.C., additional, Jongbloed-Winkel, T.A., additional, Jongkind, V., additional, Kapma, M.R., additional, Keller, B.P., additional, Khodadade Jahrome, A., additional, Kievit, J.K., additional, Klemm, P.L., additional, Klinkert, P., additional, Koedam, N.A., additional, Koelemaij, M.J., additional, Kolkert, J.L., additional, Koning, G.G., additional, Koning, O.H., additional, Konings, R., additional, Krasznai, A.G., additional, Krol, R.M., additional, Kropman, R.H., additional, Kruse, R.R., additional, van der Laan, L., additional, van der Laan, M.J., additional, van Laanen, J.H., additional, van Lammeren, G.W., additional, Lamprou, D.A., additional, Lardenoye, J.H., additional, Lauret, G.J., additional, Leenders, B.J., additional, Legemate, D.A., additional, Leijdekkers, V.J., additional, Lemson, M.S., additional, Lensvelt, M.M., additional, Lijkwan, M.A., additional, Lind, R.C., additional, van der Linden, F.T., additional, Liqui Lung, P.F., additional, Loos, M.J., additional, Loubert, M.C., additional, van de Luijtgaarden, K.M., additional, Mahmoud, D.E., additional, Manshanden, C.G., additional, Mattens, E.C., additional, Meerwaldt, R., additional, Mees, B.M., additional, von Meijenfeldt, G.C., additional, Menting, T.P., additional, Metz, R., additional, Minnee, R.C., additional, de Mol van Otterloo, J.C., additional, Molegraaf, M.J., additional, Montauban van Swijndregt, Y.C., additional, Morak, M.J., additional, van de Mortel, R.H., additional, Mulder, W., additional, Nagesser, S.K., additional, Naves, C.C., additional, Nederhoed, J.H., additional, Nevenzel-Putters, A.M., additional, de Nie, A.J., additional, Nieuwenhuis, D.H., additional, Nieuwenhuizen, J., additional, van Nieuwenhuizen, R.C., additional, Nio, D., additional, Noyez, V.J., additional, Oomen, A.P., additional, Oranen, B.I., additional, Oskam, J., additional, Palamba, H.W., additional, Peppelenbosch, A.G., additional, van Petersen, A.S., additional, Petri, B.J., additional, Pierie, M.E., additional, Ploeg, A.J., additional, Pol, R.A., additional, Ponfoort, E.D., additional, Post, I.C., additional, Poyck, P.P., additional, Prent, A., additional, ten Raa, S., additional, Raymakers, J.T., additional, Reichart, M., additional, Reichmann, B.L., additional, Reijnen, M.M., additional, de Ridder, J.A., additional, Rijbroek, A., additional, van Rijn, M.J., additional, de Roo, R.A., additional, Rouwet, E.V., additional, Saleem, B.R., additional, Salemans, P.B., additional, van Sambeek, M.R., additional, Samyn, M.G., additional, van ’t Sant, H.P., additional, van Schaik, J., additional, van Schaik, P.M., additional, Scharn, D.M., additional, Scheltinga, M.R., additional, Schepers, A., additional, Schlejen, P.M., additional, Schlosser, F.J., additional, Schol, F.P., additional, Scholtes, V.P., additional, Schouten, O., additional, Schreve, M.A., additional, Schurink, G.W., additional, Sikkink, C.J., additional, te Slaa, A., additional, Smeets, H.J., additional, Smeets, L., additional, Smeets, R.R., additional, de Smet, A.A., additional, Smit, P.C., additional, Smits, T.M., additional, Snoeijs, M.G., additional, Sondakh, A.O., additional, Speijers, M.J., additional, van der Steenhoven, T.J., additional, van Sterkenburg, S.M., additional, Stigter, D.A., additional, Stokmans, R.A., additional, Strating, R.P., additional, Stultiëns, G.N., additional, Sybrandy, J.E., additional, Teijink, J.A., additional, Telgenkamp, B.J., additional, Teraa, M., additional, Testroote, M.J., additional, Tha-In, T., additional, The, R.M., additional, Thijsse, W.J., additional, Thomassen, I., additional, Tielliu, I.F., additional, van Tongeren, R.B., additional, Toorop, R.J., additional, Tournoij, E., additional, Truijers, M., additional, Türkcan, K., additional, Tutein Nolthenius, R.P., additional, Ünlü, Ç., additional, Vaes, R.H., additional, Vafi, A.A., additional, Vahl, A.C., additional, Veen, E.J., additional, Veger, H.T., additional, Veldman, M.G., additional, Velthuis, S., additional, Verhagen, H.J., additional, Verhoeven, B.A., additional, Vermeulen, C.F., additional, Vermeulen, E.G., additional, Vierhout, B.P., additional, van der Vijver-Coppen, R.J., additional, Visser, M.J., additional, van der Vliet, J.A., additional, Vlijmen - van Keulen, C.J., additional, Voorhoeve, R., additional, van der Vorst, J.R., additional, Vos, A.W., additional, de Vos, B., additional, Vos, C.G., additional, Vos, G.A., additional, Voute, M.T., additional, Vriens, B.H., additional, Vriens, P.W., additional, de Vries, A.C., additional, de Vries, D.K., additional, de Vries, J.P., additional, de Vries, M., additional, van der Waal, C., additional, Waasdorp, E.J., additional, Wallis de Vries, B.M., additional, van Walraven, L.A., additional, van Wanroij, J.L., additional, Warlé, M.C., additional, van de Water, W., additional, van Weel, V., additional, van Well, A.M., additional, Welten, G.M., additional, Welten, R.J., additional, Wever, J.J., additional, Wiersema, A.M., additional, Wikkeling, O.R., additional, Willaert, W.I., additional, Wille, J., additional, Willems, M.C., additional, Willigendael, E.M., additional, Wilschut, E.D., additional, Wisselink, W., additional, Witte, M.E., additional, Wittens, C.H., additional, Wong, C.Y., additional, Wouda, R., additional, Yazar, O., additional, Yeung, K.K., additional, Zeebregts, C.J., additional, and van Zeeland, M.L., additional

Published
2021
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46. Circulating tumor cell-driven use of neoadjuvant chemotherapy in patients with muscle-invasive bladder cancer.

Author

Beije, Nick, primary, de Kruijff, Ingeborg Elisabeth, additional, de Jong, Joep, additional, Klaver, Sjoerd O., additional, de Vries, Peter, additional, Jacobs, Rens, additional, Somford, Diederik Meindert, additional, te Slaa, Ed, additional, van der Heijden, Toine, additional, Witjes, Johannes Alfred, additional, Fossion, Laurent, additional, Boeve, Egbert, additional, van der Hoeven, John, additional, van Melick, Harm H.E., additional, Wijburg, Carl J, additional, Martens, John W.M., additional, De Wit, Ronald, additional, Kraan, Jaco, additional, Sleijfer, Stefan, additional, and Boormans, Joost L., additional

Published
2021
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47. Nationwide Study to Predict Colonic Ischemia after Abdominal Aortic Aneurysm Repair in The Netherlands

Author

Willemsen, Saskia Irene, primary, ten Berge, Martijn Geert, additional, Statius van Eps, Randolph George, additional, Veger, Hugo Thomas Christian, additional, van Overhagen, Hans, additional, van Dijk, Lukas Carolus, additional, Putter, Hein, additional, Wever, Jan Jacob, additional, Van den Akker, L.H., additional, Van den Akker, P.J., additional, Akkersdijk, G.J., additional, Akkersdijk, G.P., additional, Akkersdijk, W.L., additional, van Andringa de Kempenaer, M.G., additional, Arts, C.H., additional, Avontuur, J.A., additional, Baal, J.G., additional, Bakker, O.J., additional, Balm, R., additional, Barendregt, W.B., additional, Bender, M.H., additional, Bendermacher, B.L., additional, van den Berg, M., additional, Berger, P., additional, Beuk, R.J., additional, Blankensteijn, J.D., additional, Bleker, R.J., additional, Bockel, J.H., additional, Bodegom, M.E., additional, Bogt, K.E., additional, Boll, A.P., additional, Booster, M.H., additional, Borger van der Burg, B.L., additional, de Borst, G.J., additional, Bos-van Rossum, W.T., additional, Bosma, J., additional, Botman, J.M., additional, Bouwman, L.H., additional, Breek, J.C., additional, Brehm, V., additional, Brinckman, M.J., additional, van den Broek, T.H., additional, Brom, H.L., additional, de Bruijn, M.T., additional, de Bruin, J.L., additional, Brummel, P., additional, van Brussel, J.P., additional, Buijk, S.E., additional, Buimer, M.G., additional, Burger, D.H., additional, Buscher, H.C., additional, den Butter, G., additional, Cancrinus, E., additional, Castenmiller, P.H., additional, Cazander, G., additional, Coveliers, H.M., additional, Cuypers, P.H., additional, Daemen, J.H., additional, Dawson, I., additional, Derom, A.F., additional, Dijkema, A.R., additional, Diks, J., additional, Dinkelman, M.K., additional, Dirven, M., additional, Dolmans, D.E., additional, van Doorn, R.C., additional, van Dortmont, L.M., additional, van der Eb, M.M., additional, Eefting, D., additional, van Eijck, G.J., additional, Elshof, J.W., additional, Elsman, B.H., additional, van der Elst, A., additional, van Engeland, M.I., additional, van Eps, R.G., additional, Faber, M.J., additional, de Fijter, W.M., additional, Fioole, B., additional, Fritschy, W.M., additional, Geelkerken, R.H., additional, van Gent, W.B., additional, Glade, G.J., additional, Govaert, B., additional, Groenendijk, R.P., additional, de Groot, H.G., additional, van den Haak, R.F., additional, de Haan, E.F., additional, Hajer, G.F., additional, Hamming, J.F., additional, van Hattum, E.S., additional, Hazenberg, C.E., additional, Hedeman Joosten, P.P., additional, Helleman, J.N., additional, van der Hem, L.G., additional, Hendriks, J.M., additional, van Herwaarden, J.A., additional, Heyligers, J.M., additional, Hinnen, J.W., additional, Hissink, R.J., additional, Ho, G.H., additional, den Hoed, P.T., additional, Hoedt, M.T., additional, van Hoek, F., additional, Hoencamp, R., additional, Hoffmann, W.H., additional, Hoksbergen, A.W., additional, Hollander, E.J., additional, Huisman, L.C., additional, Hulsebos, R.G., additional, Huntjens, K.M., additional, Idu, M.M., additional, Jacobs, M.J., additional, van der Jagt, M.F., additional, Jansbeken, J.R., additional, Janssen, R.J., additional, Jiang, H.H., additional, de Jong, S.C., additional, Jongkind, V., additional, Kapma, M.R., additional, Keller, B.P., additional, Khodadade Jahrome, A., additional, Kievit, J.K., additional, Klemm, P.L., additional, Klinkert, P., additional, Knippenberg, B., additional, Koedam, N.A., additional, Koelemaij, M.J., additional, Kolkert, J.L., additional, Koning, G.G., additional, Koning, O.H., additional, Krasznai, A.G., additional, Krol, R.M., additional, Kropman, R.H., additional, Kruse, R.R., additional, van der Laan, L., additional, van der Laan, M.J., additional, van Laanen, J.H., additional, Lardenoye, J.H., additional, Lawson, J.A., additional, Legemate, D.A., additional, Leijdekkers, V.J., additional, Lemson, M.S., additional, Lensvelt, M.M., additional, Lijkwan, M.A., additional, Lind, R.C., additional, van der Linden, F.T., additional, Liqui Lung, P.F., additional, Loos, M.J., additional, Loubert, M.C., additional, Mahmoud, D.E., additional, Manshanden, C.G., additional, Mattens, E.C., additional, Meerwaldt, R., additional, Mees, B.M., additional, Metz, R., additional, Minnee, R.C., additional, de Mol van Otterloo, J.C., additional, Moll, F.L., additional, Montauban van Swijndregt, Y.C., additional, Morak, M.J., additional, van de Mortel, R.H., additional, Mulder, W., additional, Nagesser, S.K., additional, Naves, C.C., additional, Nederhoed, J.H., additional, Nevenzel-Putters, A.M., additional, de Nie, A.J., additional, Nieuwenhuis, D.H., additional, Nieuwenhuizen, J., additional, van Nieuwenhuizen, R.C., additional, Nio, D., additional, Oomen, A.P., additional, Oranen, B.I., additional, Oskam, J., additional, Palamba, H.W., additional, Peppelenbosch, A.G., additional, van Petersen, A.S., additional, Peterson, T.F., additional, Petri, B.J., additional, Pierie, M.E., additional, Ploeg, A.J., additional, Pol, R.A., additional, Ponfoort, E.D., additional, Poyck, P.P., additional, Prent, A., additional, ten Raa, S., additional, Raymakers, J.T., additional, Reichart, M., additional, Reichmann, B.L., additional, Reijnen, M.M., additional, Rijbroek, A., additional, van Rijn, M.J., additional, de Roo, R.A., additional, Rouwet, E.V., additional, Rupert, C.G., additional, Saleem, B.R., additional, van Sambeek, M.R., additional, Samyn, M.G., additional, van’t Sant, H.P., additional, van Schaik, J., additional, van Schaik, P.M., additional, Scharn, D.M., additional, Scheltinga, M.R., additional, Schepers, A., additional, Schlejen, P.M., additional, Schlosser, F.J., additional, Schol, F.P., additional, Schouten, O., additional, Schreinemacher, M.H., additional, Schreve, M.A., additional, Schurink, G.W., additional, Sikkink, C.J., additional, Siroen, M.P., additional, te Slaa, A., additional, Smeets, H.J., additional, Smeets, L., additional, de Smet, A.A., additional, de Smit, P., additional, Smit, P.C., additional, Smits, T.M., additional, Snoeijs, M.G., additional, Sondakh, A.O., additional, van der Steenhoven, T.J., additional, van Sterkenburg, S.M., additional, Stigter, D.A., additional, Stigter, H., additional, Strating, R.P., additional, Stultiëns, G.N., additional, Sybrandy, J.E., additional, Teijink, J.A., additional, Telgenkamp, B.J., additional, Testroote, M.J., additional, The, R.M., additional, Thijsse, W.J., additional, Tielliu, I.F., additional, van Tongeren, R.B., additional, Toorop, R.J., additional, Tordoir, J.H., additional, Tournoij, E., additional, Truijers, M., additional, Türkcan, K., additional, Tutein Nolthenius, R.P., additional, Ünlü, Ç., additional, Vafi, A.A., additional, Vahl, A.C., additional, Veen, E.J., additional, Veger, H.T., additional, Veldman, M.G., additional, Verhagen, H.J., additional, Verhoeven, B.A., additional, Vermeulen, C.F., additional, Vermeulen, E.G., additional, Vierhout, B.P., additional, Visser, M.J., additional, van der Vliet, J.A., additional, Vlijmen-van Keulen, C.J., additional, Voesten, H.G., additional, Voorhoeve, R., additional, Vos, A.W., additional, de Vos, B., additional, Vos, G.A., additional, Vriens, B.H., additional, Vriens, P.W., additional, de Vries, A.C., additional, de Vries, J.P., additional, de Vries, M., additional, van der Waal, C., additional, Waasdorp, E.J., additional, Wallis de Vries, B.M., additional, van Walraven, L.A., additional, van Wanroij, J.L., additional, Warlé, M.C., additional, van Weel, V., additional, van Well, A.M., additional, Welten, G.M., additional, Welten, R.J., additional, Wever, J.J., additional, Wiersema, A.M., additional, Wikkeling, O.R., additional, Willaert, W.I., additional, Wille, J., additional, Willems, M.C., additional, Willigendael, E.M., additional, Wisselink, W., additional, Witte, M.E., additional, Wittens, C.H., additional, Wolf-de Jonge, I.C., additional, Yazar, O., additional, Zeebregts, C.J., additional, and van Zeeland, M.L., additional

Published
2021
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48. A chest-CT and clinical chemistry based flowchart for rapid COVID-19 triage at emergency departments – a multicenter study

Author

Postma B, Bob Smit, Te Slaa Cmj, Thelen Mhm, Ron Kusters, Veuger M, Kluge C, Mée Ad, Schuijt M, van Marum R, Elisen Mglm, Steef Kurstjens, van der Horst A, Eva-Leonne Göttgens, Lamboo Eh, Kluiters-de Hingh Yc, de Jager P, and Robert Herpers

Subjects
Clinical trial, business.industry, Good clinical practice, medicine, Subject (documents), Retrospective cohort study, Emergency department, Medical emergency, medicine.disease, business, Triage, Checklist, Declaration of Helsinki
Abstract

Background Due to the large number of patients with coronavirus disease 19 (COVID-19), rapid diagnosis at the emergency department (ED) is of critical importance. In this study we have developed a flowchart based on two well-known diagnostic methods: the 'corona-score' and the 'CO-RADS'. This flowchart can be used in hospitals that use chest-CT, instead of chest X-ray, for COVID-19 suspected patients at the ED. Methods ED patients (n=1904) from the Jeroen Bosch Hospital, Amphia Hospital, HagaHospital, Elisabeth TweeSteden Hospital, Bernhoven Hospital and Slingeland Hospital were included. A laboratory-based 'corona-score', without radiology, called the 'lab-corona-score' was combined with a chest-CT based radiology scoring system (CO-RADS), to develop a flowchart. The performance was assessed by sensitivity/specificity analyses using the RT-PCR outcome or the physician's final diagnosis as golden standard. Results Out of the 1904 patients, 611 (32.1%) patients tested positive for the SARS-CoV-2 virus. The lab-corona-score alone had an AUC of 0.86, a sensitivity of 87% and a specificity of 88% using cut-off values of 0−2 (negative) and 8−10 (positive). Of 255 patients, from the Amphia and Slingeland Hospitals, a CO-RADS score was determined. The flowchart, which combined the 'CO-RADS' with the 'lab-corona-score', was developed based on data from Slingeland Hospital (sensitivity 97%, specificity 96%). Hereafter, the performance of the flowchart was validated using an independent dataset from Amphia hospital, and reached a sensitivity of 98% and specificity of 93%. A decision could be made in 79% of the patients, which was correct in 95% of the cases. Conclusion This flowchart, based on radiology (CO-RADS) and clinical chemistry parameters (lab-corona-score), results in a rapid and accurate diagnosis of COVID-19 at the ED. ### Competing Interest Statement The authors have declared no competing interest. ### Funding Statement No funding ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Yes The details of the IRB/oversight body that provided approval or exemption for the research described are given below: This study was conducted according to the declaration of Helsinki and Guidelines for Good Clinical Practice. The execution of this retrospective observational study of patient records was approved by the regional Medical Research Ethics Committee (METC Brabant), which declared that the use of anonymized patient data is not subject to the regulations of the WMO (Dutch Medical Research Involving Human Subjects Act). Consent was obtained by an opt-out agreement. All necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived. Yes I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). Yes I have followed all appropriate research reporting guidelines and uploaded the relevant EQUATOR Network research reporting checklist(s) and other pertinent material as supplementary files, if applicable. Yes Data and further information are available upon reasonable request

Published
2020
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49. National Numbers of Secondary Aortic Reinterventions after Primary Abdominal Aortic Aneurysm Surgery from the Dutch Surgical Aneurysm Audit

Author

Eleonora G. Karthaus, Anco Vahl, Bernard H.P. Elsman, Michel W.J.M. Wouters, Gert J. de Borst, Jaap F. Hamming, P.J. Van den Akker, G.J. Akkersdijk, G.P. Akkersdijk, W.L. Akkersdijk, M.G. van Andringa de Kempenaer, C.H. Arts, J.A. Avontuur, O.J. Bakker, R. Balm, W.B. Barendregt, J.A. Bekken, M.H. Bender, B.L. Bendermacher, M. van den Berg, P. Berger, R.J. Beuk, J.D. Blankensteijn, R.J. Bleker, J.J. Blok, A.S. Bode, M.E. Bodegom, K.E. van der Bogt, A.P. Boll, M.H. Booster, B.L. Borger van der Burg, G.J. de Borst, W.T. Bos-van Rossum, J. Bosma, J.M. Botman, L.H. Bouwman, V. Brehm, M.T. de Bruijn, J.L. de Bruin, P. Brummel, J.P. van Brussel, S.E. Buijk, M.A. Buijs, M.G. Buimer, D.H. Burger, H.C. Buscher, E. Cancrinus, P.H. Castenmiller, G. Cazander, A.M. Coester, P.H. Cuypers, J.H. Daemen, I. Dawson, J.E. Dierikx, M.L. Dijkstra, J. Diks, M.K. Dinkelman, M. Dirven, D.E. Dolmans, R.C. van Doorn, L.M. van Dortmont, J.W. Drouven, M.M. van der Eb, D. Eefting, G.J. van Eijck, J.W. Elshof, B.H. Elsman, A. van der Elst, M.I. van Engeland, R.G. van Eps, M.J. Faber, W.M. de Fijter, B. Fioole, T.M. Fokkema, F.A. Frans, W.M. Fritschy, P.H. Fung Kon Jin, R.H. Geelkerken, W.B. van Gent, G.J. Glade, B. Govaert, R.P. Groenendijk, H.G. de Groot, R.F. van den Haak, E.F. de Haan, G.F. Hajer, J.F. Hamming, E.S. van Hattum, C.E. Hazenberg, P.P. Hedeman Joosten, J.N. Helleman, L.G. van der Hem, J.M. Hendriks, J.A. van Herwaarden, J.M. Heyligers, J.W. Hinnen, R.J. Hissink, G.H. Ho, P.T. den Hoed, M.T. Hoedt, F. van Hoek, R. Hoencamp, W.H. Hoffmann, W. Hogendoorn, A.W. Hoksbergen, E.J. Hollander, M. Hommes, C.J. Hopmans, L.C. Huisman, R.G. Hulsebos, K.M. Huntjens, M.M. Idu, M.J. Jacobs, M.F. van der Jagt, J.R. Jansbeken, R.J. Janssen, H.H. Jiang, S.C. de Jong, T.A. Jongbloed-Winkel, V. Jongkind, M.R. Kapma, B.P. Keller, A. Khodadade Jahrome, J.K. Kievit, P.L. Klemm, P. Klinkert, N.A. Koedam, M.J. Koelemaij, J.L. Kolkert, G.G. Koning, O.H. Koning, R. Konings, A.G. Krasznai, R.M. Krol, R.H. Kropman, R.R. Kruse, L. van der Laan, M.J. van der Laan, J.H. van Laanen, G.W. van Lammeren, D.A. Lamprou, J.H. Lardenoye, G.J. Lauret, B.J. Leenders, D.A. Legemate, V.J. Leijdekkers, M.S. Lemson, M.M. Lensvelt, M.A. Lijkwan, R.C. Lind, F.T. van der Linden, P.F. Liqui Lung, M.J. Loos, M.C. Loubert, K.M. van de Luijtgaarden, D.E. Mahmoud, C.G. Manshanden, E.C. Mattens, R. Meerwaldt, B.M. Mees, G.C. von Meijenfeldt, T.P. Menting, R. Metz, R.C. Minnee, J.C. de Mol van Otterloo, M.J. Molegraaf, Y.C. Montauban van Swijndregt, M.J. Morak, R.H. van de Mortel, W. Mulder, S.K. Nagesser, C.C. Naves, J.H. Nederhoed, A.M. Nevenzel-Putters, A.J. de Nie, D.H. Nieuwenhuis, J. Nieuwenhuizen, R.C. van Nieuwenhuizen, D. Nio, V.J. Noyez, A.P. Oomen, B.I. Oranen, J. Oskam, H.W. Palamba, A.G. Peppelenbosch, A.S. van Petersen, B.J. Petri, M.E. Pierie, A.J. Ploeg, R.A. Pol, E.D. Ponfoort, I.C. Post, P.P. Poyck, A. Prent, S. ten Raa, J.T. Raymakers, M. Reichart, B.L. Reichmann, M.M. Reijnen, J.A. de Ridder, A. Rijbroek, M.J. van Rijn, R.A. de Roo, E.V. Rouwet, B.R. Saleem, P.B. Salemans, M.R. van Sambeek, M.G. Samyn, H.P. van't Sant, J. van Schaik, P.M. van Schaik, D.M. Scharn, M.R. Scheltinga, A. Schepers, P.M. Schlejen, F.J. Schlosser, F.P. Schol, V.P. Scholtes, O. Schouten, M.A. Schreve, G.W. Schurink, C.J. Sikkink, A. te Slaa, H.J. Smeets, L. Smeets, R.R. Smeets, A.A. de Smet, P.C. Smit, T.M. Smits, M.G. Snoeijs, A.O. Sondakh, M.J. Speijers, T.J. van der Steenhoven, S.M. van Sterkenburg, D.A. Stigter, R.A. Stokmans, R.P. Strating, G.N. Stultiëns, J.E. Sybrandy, J.A. Teijink, B.J. Telgenkamp, M. Teraa, M.J. Testroote, T. Tha-In, R.M. The, W.J. Thijsse, I. Thomassen, I.F. Tielliu, R.B. van Tongeren, R.J. Toorop, E. Tournoij, M. Truijers, K. Türkcan, R.P. Tutein Nolthenius, Ç. Ünlü, R.H. Vaes, A.A. Vafi, A.C. Vahl, E.J. Veen, H.T. Veger, M.G. Veldman, S. Velthuis, H.J. Verhagen, B.A. Verhoeven, C.F. Vermeulen, E.G. Vermeulen, B.P. Vierhout, R.J. van der Vijver-Coppen, M.J. Visser, J.A. van der Vliet, C.J. Vlijmen-van Keulen, R. Voorhoeve, J.R. van der Vorst, A.W. Vos, B. de Vos, C.G. Vos, G.A. Vos, M.T. Voute, B.H. Vriens, P.W. Vriens, A.C. de Vries, D.K. de Vries, J.P. de Vries, M. de Vries, C. van der Waal, E.J. Waasdorp, W. de Vries, L.A. van Walraven, J.L. van Wanroij, M.C. Warlé, W. van de Water, V. van Weel, A.M. van Well, G.M. Welten, R.J. Welten, J.J. Wever, A.M. Wiersema, O.R. Wikkeling, W.I. Willaert, J. Wille, M.C. Willems, E.M. Willigendael, E.D. Wilschut, W. Wisselink, M.E. Witte, C.H. Wittens, C.Y. Wong, R. Wouda, O. Yazar, K.K. Yeung, C.J. Zeebregts, M.L. van Zeeland, Surgery, ACS - Atherosclerosis & ischemic syndromes, Pathology, VU University medical center, Pediatrics, Dermatology, ACS - Microcirculation, ACS - Diabetes & metabolism, Amsterdam Gastroenterology Endocrinology Metabolism, Multi-Modality Medical Imaging, Technical Medicine, RS: CAPHRI - R5 - Optimising Patient Care, and Epidemiologie

Subjects
Male, Time Factors, medicine.medical_treatment, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], UT-Hybrid-D, EVAR TRIAL 1, OPEN REPAIR, 030204 cardiovascular system & hematology, Endovascular aneurysm repair, 030218 nuclear medicine & medical imaging, Postoperative Complications, 0302 clinical medicine, LONG-TERM OUTCOMES, Risk Factors, FAILURE, Registries, skin and connective tissue diseases, Netherlands, Aged, 80 and over, Medical Audit, Endovascular Procedures, General Medicine, EDITORS CHOICE, Abdominal aortic aneurysm, Treatment Outcome, Cohort, cardiovascular system, INSTRUCTIONS, Female, Cardiology and Cardiovascular Medicine, Reoperation, medicine.medical_specialty, Blood Vessel Prosthesis Implantation, 03 medical and health sciences, Aneurysm, medicine, Humans, Aged, Surgical repair, business.industry, MORTALITY, fungi, Stent, ENDOVASCULAR REPAIR, Odds ratio, medicine.disease, Confidence interval, Surgery, body regions, business, SYSTEM, Aortic Aneurysm, Abdominal
Abstract

Contains fulltext : 226469.pdf (Publisher’s version ) (Open Access) BACKGROUND: Long-term secondary aortic reinterventions (SARs) can be a sign of (lack of) effectiveness of abdominal aortic aneurysm (AAA) surgery. This study provides insight into the national number of SARs after primary AAA repair by endovascular aneurysm repair (EVAR) or by open surgical repair in the Netherlands. METHODS: Observational study included all patients undergoing SAR between 2016 and 2017, registered in the compulsory Dutch Surgical Aneurysm Audit (DSAA). The DSAA started in 2013, SARs are registered from 2016. Characteristics of SAR and postoperative outcomes (mortality/complications) were analyzed, stratified by urgency of SAR. Data of SARs were merged with data of their preceded primary AAA repair, registered in the DSAA after January 2013. In these patients undergoing SAR, treatment characteristics of the preceded primary AAA repair were additionally described, with focus on differences between stent grafts. RESULTS: Between 2016 and 2017, 691 patients underwent SAR, this concerned 9.3% of all AAA procedures (infrarenal/juxtarenal/suprarenal) in the Netherlands (77% elective/11% acute symptomatic/12% ruptured). Endoleak (60%) was the most frequent indication for SAR. SARs were performed with EVAR in 66%. Postoperative mortalities after SAR were 3.4%, 11%, and 29% in elective, acute symptomatic, and ruptured patients, respectively. In 26% (n = 181) of the patients undergoing SAR their primary AAA repair was performed after January 2013 and data of primary and SAR procedures could be merged. In 93% (n = 136), primary AAA repair was EVAR. Endografts primarily used were nitinol/polyester (62%), nitinol/polytetrafluoroethylene (8%), endovascular sealing (21%), and others (9%), compared with their national market share of 76% (odds ratio [OR], 0.52; 95% confidence interval [CI], 0.38-0.71), 15% (OR, 0.50; CI, 0.29-0.89), 4.9% (OR, 5.04; CI, 3.44-7.38), and 4.1% (OR, 2.81; CI, 1.66-4.74), respectively. CONCLUSIONS: In the Netherlands, about one-tenth of the annual AAA procedures concerns an SAR. A quarter of this cohort had an SAR within 1-5 years after their primary AAA repair. Most SARs followed after primary EVAR procedures, in which an overrepresentation of endovascular sealing grafts was seen. Postoperative mortality after SAR is comparable with primary AAA repair.

Published
2020
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50. A Composite Measure for Quality of Care in Patients with Symptomatic Carotid Stenosis Using Textbook Outcome

Author

Laurien S. Kuhrij, Eleonora G. Karthaus, Anco C. Vahl, Martine C.M. Willems, Jan W. Elshof, Gert J. de Borst, P.J. Van den Akker, G.J. Akkersdijk, G.P. Akkersdijk, W.L. Akkersdijk, M.G. van Andringa de Kempenaer, C.H. Arts, J.A. Avontuur, O.J. Bakker, R. Balm, W.B. Barendregt, J.A. Bekken, M.H. Bender, B.L. Bendermacher, M. van den Berg, P. Berger, R.J. Beuk, J.D. Blankensteijn, R.J. Bleker, J.J. Blok, A.S. Bode, M.E. Bodegom, K.E. van der Bogt, A.P. Boll, M.H. Booster, B.L. Borger van der Burg, G.J. de Borst, W.T. Bos-van Rossum, J. Bosma, J.M. Botman, L.H. Bouwman, V. Brehm, M.T. de Bruijn, J.L. de Bruin, P. Brummel, J.P. van Brussel, S.E. Buijk, M.A. Buijs, M.G. Buimer, D.H. Burger, H.C. Buscher, E. Cancrinus, P.H. Castenmiller, G. Cazander, A.M. Coester, P.H. Cuypers, J.H. Daemen, I. Dawson, J.E. Dierikx, M.L. Dijkstra, J. Diks, M.K. Dinkelman, M. Dirven, D.E. Dolmans, R.C. van Doorn, L.M. van Dortmont, J.W. Drouven, M.M. van der Eb, D. Eefting, G.J. van Eijck, J.W. Elshof, B.H. Elsman, A. van der Elst, M.I. van Engeland, R.G. van Eps, M.J. Faber, W.M. de Fijter, B. Fioole, T.M. Fokkema, F.A. Frans, W.M. Fritschy, P.H. Fung Kon Jin, R.H. Geelkerken, W.B. van Gent, G.J. Glade, B. Govaert, R.P. Groenendijk, H.G. de Groot, R.F. van den Haak, E.F. de Haan, G.F. Hajer, J.F. Hamming, E.S. van Hattum, C.E. Hazenberg, P.P. Hedeman Joosten, J.N. Helleman, L.G. van der Hem, J.M. Hendriks, J.A. van Herwaarden, J.M. Heyligers, J.W. Hinnen, R.J. Hissink, G.H. Ho, P.T. den Hoed, M.T. Hoedt, F. van Hoek, R. Hoencamp, W.H. Hoffmann, W. Hogendoorn, A.W. Hoksbergen, E.J. Hollander, M. Hommes, C.J. Hopmans, L.C. Huisman, R.G. Hulsebos, K.M. Huntjens, M.M. Idu, M.J. Jacobs, M.F. van der Jagt, J.R. Jansbeken, R.J. Janssen, H.H. Jiang, S.C. de Jong, T.A. Jongbloed-Winkel, V. Jongkind, M.R. Kapma, B.P. Keller, A. Khodadade Jahrome, J.K. Kievit, P.L. Klemm, P. Klinkert, N.A. Koedam, M.J. Koelemaij, J.L. Kolkert, G.G. Koning, O.H. Koning, R. Konings, A.G. Krasznai, R.M. Krol, R.H. Kropman, R.R. Kruse, L. van der Laan, M.J. van der Laan, J.H. van Laanen, G.W. van Lammeren, D.A. Lamprou, J.H. Lardenoye, G.J. Lauret, B.J. Leenders, D.A. Legemate, V.J. Leijdekkers, M.S. Lemson, M.M. Lensvelt, M.A. Lijkwan, R.C. Lind, F.T. van der Linden, P.F. Liqui Lung, M.J. Loos, M.C. Loubert, K.M. van de Luijtgaarden, D.E. Mahmoud, C.G. Manshanden, E.C. Mattens, R. Meerwaldt, B.M. Mees, G.C. von Meijenfeldt, T.P. Menting, R. Metz, R.C. Minnee, J.C. de Mol van Otterloo, M.J. Molegraaf, Y.C. Montauban van Swijndregt, M.J. Morak, R.H. van de Mortel, W. Mulder, S.K. Nagesser, C.C. Naves, J.H. Nederhoed, A.M. Nevenzel-Putters, A.J. de Nie, D.H. Nieuwenhuis, J. Nieuwenhuizen, R.C. van Nieuwenhuizen, D. Nio, V.J. Noyez, A.P. Oomen, B.I. Oranen, J. Oskam, H.W. Palamba, A.G. Peppelenbosch, A.S. van Petersen, B.J. Petri, M.E. Pierie, A.J. Ploeg, R.A. Pol, E.D. Ponfoort, I.C. Post, P.P. Poyck, A. Prent, S. ten Raa, J.T. Raymakers, M. Reichart, B.L. Reichmann, M.M. Reijnen, J.A. de Ridder, A. Rijbroek, M.J. van Rijn, R.A. de Roo, E.V. Rouwet, B.R. Saleem, P.B. Salemans, M.R. van Sambeek, M.G. Samyn, H.P. van ’t Sant, J. van Schaik, P.M. van Schaik, D.M. Scharn, M.R. Scheltinga, A. Schepers, P.M. Schlejen, F.J. Schlosser, F.P. Schol, V.P. Scholtes, O. Schouten, M.A. Schreve, G.W. Schurink, C.J. Sikkink, A. te Slaa, H.J. Smeets, L. Smeets, R.R. Smeets, A.A. de Smet, P.C. Smit, T.M. Smits, M.G. Snoeijs, A.O. Sondakh, M.J. Speijers, T.J. van der Steenhoven, S.M. van Sterkenburg, D.A. Stigter, R.A. Stokmans, R.P. Strating, G.N. Stultiëns, J.E. Sybrandy, J.A. Teijink, B.J. Telgenkamp, M. Teraa, M.J. Testroote, T. Tha-In, R.M. The, W.J. Thijsse, I. Thomassen, I.F. Tielliu, R.B. van Tongeren, R.J. Toorop, E. Tournoij, M. Truijers, K. Türkcan, R.P. Tutein Nolthenius, Ç. Ünlü, R.H. Vaes, A.A. Vafi, A.C. Vahl, E.J. Veen, H.T. Veger, M.G. Veldman, S. Velthuis, H.J. Verhagen, B.A. Verhoeven, C.F. Vermeulen, E.G. Vermeulen, B.P. Vierhout, R.J. van der Vijver-Coppen, M.J. Visser, J.A. van der Vliet, C.J. Vlijmen - van Keulen, R. Voorhoeve, J.R. van der Vorst, A.W. Vos, B. de Vos, C.G. Vos, G.A. Vos, M.T. Voute, B.H. Vriens, P.W. Vriens, A.C. de Vries, D.K. de Vries, J.P. de Vries, M. de Vries, C. van der Waal, E.J. Waasdorp, B.M. Wallis de Vries, L.A. van Walraven, J.L. van Wanroij, M.C. Warlé, W. van de Water, V. van Weel, A.M. van Well, G.M. Welten, R.J. Welten, J.J. Wever, A.M. Wiersema, O.R. Wikkeling, W.I. Willaert, J. Wille, M.C. Willems, E.M. Willigendael, E.D. Wilschut, W. Wisselink, M.E. Witte, C.H. Wittens, C.Y. Wong, R. Wouda, O. Yazar, K.K. Yeung, C.J. Zeebregts, M.L. van Zeeland, Surgery, ACS - Atherosclerosis & ischemic syndromes, Pathology, VU University medical center, Pediatrics, ACS - Microcirculation, ACS - Diabetes & metabolism, Multi-Modality Medical Imaging, Technical Medicine, RS: CAPHRI - R5 - Optimising Patient Care, Epidemiologie, Graduate School, ANS - Neurovascular Disorders, APH - Methodology, and APH - Quality of Care

Subjects
Male, Time Factors, medicine.medical_treatment, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], Psychological intervention, UT-Hybrid-D, Carotid endarterectomy, 030204 cardiovascular system & hematology, 030230 surgery, Logistic regression, 0302 clinical medicine, Risk Factors, Carotid Stenosis, Registries, Stroke, Netherlands, Outcome, Aged, 80 and over, RISK, Endarterectomy, Carotid, ENDARTERECTOMY, Middle Aged, Outcome and Process Assessment, Health Care, Treatment Outcome, Ischemic Attack, Transient, Female, Cardiology and Cardiovascular Medicine, medicine.medical_specialty, Funnel plot, Postoperative Hemorrhage, Patient Readmission, 03 medical and health sciences, Case mix index, Internal medicine, medicine, Humans, HOSPITAL QUALITY, Healthcare Disparities, Aged, Quality Indicators, Health Care, business.industry, Quality of care, 22/2 OA procedure, Length of Stay, medicine.disease, Comorbidity, Cranial Nerve Diseases, Stenosis, Surgery, business
Abstract

Contains fulltext : 226467.pdf (Publisher’s version ) (Closed access) OBJECTIVE: Composite measures may better objectify hospital performance than individual outcome measures (IOM). Textbook outcome (TO) is an outcome measure achieved for an individual patient when all undesirable outcomes are absent. The aim of this study was to assess TO as an additional outcome measure to evaluate quality of care in symptomatic patients treated by carotid endarterectomy (CEA). METHODS: All symptomatic patients treated by CEA in 2018, registered in the Dutch Audit for Carotid Interventions, were included. TO was defined as a composite of the absence of 30 day mortality, neurological events (any stroke or transient ischaemic attack [TIA]), cranial nerve deficit, haemorrhage, 30 day readmission, prolonged length of stay (LOS; > 5 days) and any other surgical complication. Multivariable logistic regression was used to identify covariables associated with achieving TO, which were used for casemix adjustment for hospital comparison. For each hospital, an observed vs. expected number of events ratio (O/E ratio) was calculated and plotted in a funnel plot with 95% control limits. RESULTS: In total, 70.7% of patients had a desired outcome within 30 days after CEA and therefore achieved TO. Prolonged LOS was the most common parameter (85%) and mortality the least common (1.1%) for not achieving TO. Covariates associated with achieving TO were younger age, the absence of pulmonary comorbidity, higher haemoglobin levels, and TIA as index event. In the case mix adjusted funnel plot, the O/E ratios between hospitals ranged between 0.63 and 1.27, with two hospitals revealing a statistically significantly lower rate of TO (with O/E ratios of 0.63 and 0.66). CONCLUSION: In the Netherlands, most patients treated by CEA achieve TO. Variation between hospitals in achieving TO might imply differences in performance. TO may be used as an additive to the pre-existing IOM, especially in surgical care with low baseline risk such as CEA.

Published
2020
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