Search

To date, one of the important and urgent tasks of the science of electrodynamics is to study the scattering characteristics of various complex electrodynamic objects. Among them, hollow structures can be distinguished, which are part of antenna systems and structures of various technical facilities. Their contribution to the levels of electromagnetic fields in the anterior hemisphere can be quite large. The correct solution to the problem of scattering of electromagnetic wave scattering characteristics is associated with the use of appropriate methods. The paper considers the solution of the problem based on the method of integral equations. During the analysis of the two-frequency effect, the use of the wavelet transform is considered.

When managing organizations, it is necessary in many cases to implement personnel management procedures. The paper proposes to use the methodology of cognitive modeling. Then the most effective management decisions and scenarios for the development of events can be selected using the fact that concepts are distinguished that will characterize the current situation in a qualitative and quantitative way. In addition, estimates of the mutual influence of factors are considered. The method of cognitive modeling of the processes of managing the development of the organization's personnel is proposed. In the course of its implementation, cognitive maps are formed. A block diagram aimed at cognitive and simulation dynamic analysis and modeling is presented. The implementation of the development of strategies and forecasts of how the personnel of the organization will develop with the involvement of a cognitive approach is considered in the form of the presented analytical technology. Suggestions for an intelligent advising system are given. The functions that are designed to solve problems related to the development of the company's personnel are shown. In the results, based on the proposed approach, an illustration of the developed scheme of causal relationships in the analysis of violations of technological discipline is given. The results of the work can be useful in modeling and managing the work of personnel in corporate information systems.

The development of unmanned aerial vehicles can be regarded as a promising direction of modern aviation. They have significantly reduced dimensional characteristics, if compared with traditional aircraft. It is also possible to form unmanned aerial vehicles, which are aimed at performing corresponding tasks. It takes less time to train a specialist to fly an unmanned aerial vehicle compared to conventional pilots. The work is related to the creation of mathematical models that allow an integral way to evaluate the effectiveness and conduct cluster structuring of a swarm of wireless aircraft. At the same time, there are opportunities to take into account the limited resources, to carry out redistribution of resources. Resources are distributed among clusters, and the principle of inverse priorities has to be applied. After that, the distribution over the drones of the network structure that has been optimized is implemented. Monitoring information is used. The main stages of solving the problem, which are based on optimization procedures, are shown.

In the existing conditions in various companies, it is possible to observe an increase in the complexity of automation of many processes. Therefore, there is a need for distributed automated systems. They are required to operate under the constraints of real-time control and communication in manufacturing processes. In cyber-physical systems, a fully synergistic integration of control computation with physical devices and processes is implied. In addition, the incorporation of a cyber-physical system into automated plant systems will provide opportunities for unifying automated process control. Due to the automated control of production and enterprise as a whole, it is possible to form a controlled system, from order to realization. It is proposed to form a training and research system to work with cyber-physical system. Intelligent support for specialists within cyber-physical systems is associated with corresponding performance requirements. An illustration of a schematic of a training and research system for personnel management in a cyber-physical system is presented. A schematic of the training subsystem is shown. Instrumental examination within the research subsystem provides opportunities to realize the creation of an information support structure. An illustration of the schematic diagram of the analysis research subsystem is presented. A structure for conducting automated modeling of processes within a cyber-physical system is shown.

The study of various properties of information-technical systems from the point of view of interaction of their physical and digital components is a new and actual direction of modern science of cyber-physical systems. When considering modern cyber-physical systems, various authors recommend considering them as complex systems within the framework of system analysis. Due to the complexity of systems, adaptive algorithms should be relied upon in human-machine interaction. In this case, the specialist is seen as a decision maker. In the course of his work, he will strive to ensure the required mode of functioning of the cyber-physical system, including in the presence of faults in it. This paper proposes to consider the possible actions of a specialist in a cyber-physical system from the perspective of a simulation experiment. The paper provides an illustration of an algorithm scheme related to adaptive resource selection in a cyber-physical system. The scheme of rational decision making when resources are selected is shown. A methodology for generating logic models is proposed. The paper shows how game modeling can be applied to cyber-physical systems. The results obtained in this paper can be applied to a wide range of cyberphysical systems.

The main task of networks is to transport information from the sending computer to the receiving computer. In most cases, you need to make several transfers to do this. The problem of choosing a path is solved by routing algorithms. The routing algorithm must have well-defined properties: reliability, correctness, stability, simplicity and optimality. The latter property is not as transparent as it may seem at first glance, it all depends on which or which parameters are optimized. This task is sometimes not at all easy even for relatively simple local networks. Optimization parameters may include minimum delivery delay, maximum throughput, minimum price, maximum reliability, or minimum error probability. In this paper, reactive, proactive and hybrid routing protocols are considered. When making their choice, we relied on the method of hierarchy analysis. Based on the results obtained during the simulation of a network with video conference traffic, a matrix was constructed for each of the criteria studied. The protocols were compared in terms of the possibility of information loss. The results of the research can be useful in the course of building modern computer networks.

In the existing conditions in various companies, it is possible to observe an increase in the complexity of automation of many processes. Therefore, there is a need for distributed automated systems. They are required to work under conditions of limited real-time control and communication in production processes. Cyberphysical systems imply a fully synergetic integration of computing and control with physical devices and processes. In addition, the introduction of a cyber-physical system into the automated systems of the enterprise will provide opportunities for combining automated process control. Due to the automated management of production and the enterprise as a whole, it is possible to form a managed system, from order to implementation. It is proposed to form an educational and research system for working with the cyberphysical system. The intellectual support of specialists within cyber-physical systems is related to the corresponding efficiency requirements. An illustration of the scheme of an educational and research system for personnel management in a cyberphysical system is presented. The diagram of the training subsystem is shown. Instrumental examination within the research subsystem provides opportunities to implement the creation of an information support structure. An illustration of the scheme of the research subsystem of analysis is presented. Structures for conducting automated modeling of processes inside a cyberphysical system are shown.

Lipid peroxidation plays an important role in various pathologies and aging, at least partially mediated by ferroptosis. The role of mitochondrial lipid peroxidation during ferroptosis remains poorly understood. We show that supplementation of exogenous iron in the form of ferric ammonium citrate at submillimolar doses induces production of reactive oxygen species (ROS) and lipid peroxidation in mitochondria that precede ferroptosis in H9c2 cardiomyocytes. The mitochondria-targeted antioxidant SkQ1 and the redox mediator methylene blue, which inhibits the production of ROS in complex I of the mitochondrial electron transport chain, prevent both mitochondrial lipid peroxidation and ferroptosis. SkQ1 and methylene blue also prevented accumulation of lipofuscin observed after 24 h incubation of cardiomyocytes with ferric ammonium citrate. Using isolated cardiac mitochondria as an in vitro ferroptosis model, it was shown that rotenone (complex I inhibitor) in the presence of ferrous iron stimulates lipid peroxidation and lipofuscin accumulation. Our data indicate that ROS generated in complex I stimulate mitochondrial lipid peroxidation, lipofuscin accumulation, and ferroptosis induced by exogenous iron.

Cyber-physical systems (CPS), along with cyber-biological and cybersocial systems, have recently become one of the key elements of modern infotelecommunications systems. The Internet of Things, as a revolutionary concept of the past few years, is a fundamental concept in the context of SPS. However, unlike the Internet of Things, which primarily emphasizes machine-to-machine connections, the SPS concept is based on the dualism of physical and cybernetic (information) environments. Turning to the applied field, we should note the trend towards informatization of many elements of the world around us. The degree of penetration ranges from sensors transmitting information about the state of a living organism to precise models describing the current state of an element within a smart production. This paper deals with the problem related to the control of cyber-physical systems under conditions where various random external influences are exerted on them. On the basis of game theory, the paper proposes, taking into account various criteria, to carry out the choice of control. Examples of calculations are considered.

Modern electronic devices are characterized by complex circuit design solutions, which requires performing their design using high-performance circuit design computer-aided design systems. The development of such computer-aided design systems is associated with significant expenditure of time and labor resources and should be based on new approaches to the construction of mathematical and software, taking into account the specific features of the subject area and the nature of the tasks to be solved. In this paper, the problems associated with the modeling of maintenance of electrical complex are considered. A methodology for predicting components based on a single attribute within an experiment is demonstrated. The criterion in terms of risk assessment for the consumer is considered. The results of modeling the main parameters characterizing the quality of electrolytic capacitors are presented. After the tests are completed, the value of the predicted parameter is determined for each realization. The optimum value of leakage current, providing the minimum probability of error, for tantalum electrolytic capacitors with nominal capacity is shown. The results of the research can be useful for specialists working on electrical engineering complexes.

The modern stage of development of radio information systems is characterized by one general tendency. It consists in that object of their processing are various kinds of images, difficult enough on structure and with heterogeneous statistical properties. Television, diagnostic and security systems, observation systems for land and water surfaces, near space can serve as an example. The task of such systems is not only a passive function such as formation of images themselves, but first of all the understanding of images - detection on a complex statistically heterogeneous and multigradational in brightness background of the objects of interest, recognition and evaluation of their parameters. The image form is a concentrator of information contained in the image. It is interpreted as an analytically defined signal. This paper proposes a subsystem for the recognition of signals of complex shape, based on sensor networks. The illustration of the structural scheme of the subsystem is given. The technique of image recognition is shown. The results of the recognition are presented.

This article discusses the specifics of managing a service-related company. It shows how the preparation of input data and their transformation takes place. Peculiarities of model preparation for training and testing are demonstrated. The general scheme of interaction between customer end-users and project and third-party technical support taking into account the conditions of service maintenance is given. The scheme of logic of processing incoming incidents between support lines is shown. The logic diagram of the prediction module for determining the support team is given. After the work has received the trained model that allows to carry out prediction of a support team on the basis of methods of logistic regression, by means of language Python it can be saved as a special file, it can then be connected as an independent module. Purpose. Determination of methods and techniques of analysis used in the analysis of export operations. Methodology the article used systems analysis and enterprise management methods. Results: an example of resolved incident data for a specific support team with engineers is considered, as well as an example of numerical feature calculations to adjust the support team engineer’s baseline prediction. A logic diagram of the improved software solution model is shown. Practical implications can be used with the improvement of IT service management in terms of incident coordinator activities.

The task of a transportation system is to ensure the safe and efficient delivery of goods and transportation of passengers. Effective management of transport systems is aimed not only at ensuring the optimal passage of all processes within such systems. The main task in this case is to create conditions capable of ensuring the mobility of the population and the volume of cargo transportation which will meet the objectives of economic development. Thus, the degree of efficiency of the transport system can be determined on the basis of its ability to ensure a balance between economic requirements and social demands, which often contradict each other. Features of transport system management organization: spatial location of system elements on a large territory, the need to strictly observe technological functions affecting the safety of transportation, one-man management, dispatching and discipline in the organization of transport processes, close interaction and mutual dependence of all elements of the transport system. The paper considers the task of interaction between the control center and the objects in the transport system. The mechanisms of rating evaluations are applied. The illustration of the structural scheme, on the basis of which the mechanisms of rating management are implemented, is given. The results have demonstrated the efficiency of the approaches used. They can be used in evaluating the performance of a wide range of transportation systems.

The analysis shows that the real information flows are characterized by: arbitrary distribution function; the presence of both quantitative and qualitative indicators; the absence of part of the meaningful data fragments; unreliability of data associated with errors in registration and their entry; parametric redundancy. Not all of the existing tools included in most of the instrumental systems, make it possible to solve a number of these problems. The article deals with the problem related to information filtering. The illustration of an algorithm scheme, which allows to conduct information filtering, is presented. The stages used in the construction of the algorithm are specified in detail. The geometric approach is applied. It gives an opportunity to lead consideration of information messages in the form of “constellations” which are connected with the i-dimensional feature hyperspace. An algorithm that allows to implement gap filling is proposed. The results presented in the paper can be useful when considering different information flows in modern information systems.

Optimization of transport work is necessary in case of uncontrollable growth of the described costs. The process of optimizing transport costs at the enterprise begins with an analysis of the current logistics strategy and collection of recommendations for its correction. The following aspects of the transport system of the company are subject to analysis: the method of movement of goods; the choice of vehicle type and its specific model; the selection of the carrier company and other logistics intermediaries; the layout of the company’s storage terminals. An optimized transport system can reduce the cost of production and sales of products and increase staff efficiency. There are three main directions in which innovations will ensure the reduction of costs for cargo and passenger transportation: the choice of optimal vehicles, the selection of optimally located unloading and loading points, the analysis of the feasibility of own fleet of vehicles. The paper considers the possibilities of transport system management under the condition of external influences. An illustration of the algorithm scheme of solving the optimization problem related to the choice of initial actions is given. The possibility of using prognostic models is shown. The approaches proposed in the work can be useful in improving the performance of various transportation systems.

Ferroptosis induced by erastin (an inhibitor of cystine transport) and butionine sulfoximine (an inhibitor of glutathione biosynthesis) was prevented by the mitochondria-targeted antioxidants SkQ1 and MitoTEMPO. These effects correlate with the prevention of mitochondrial lipid peroxidation, which precedes cell death. Methylene blue, a redox agent that inhibits the production of reactive oxygen species (ROS) in complex I of the mitochondrial electron transport chain, also inhibits ferroptosis and mitochondrial lipid peroxidation. Activation of ROS production in complex I with rotenone in the presence of ferrous iron stimulates lipid peroxidation in isolated mitochondria, while ROS produced by complex III are ineffective. SkQ1 and methylene blue inhibit lipid peroxidation. We suggest that ROS formed in complex I promote mitochondrial lipid peroxidation and ferroptosis.

The aim of this pilot study was to examine the effectiveness of a CrossFit-based training program to enhance the general and sport-specific physical fitness of 10–12-year-old judokas. The study was conducted between September 2021 and February 2022. The pedagogical research experiment was designed to be one complete, annual macrocycle (September–June). The current study presents mid-point data. Twenty male participants (3 years average sports experience; age = 11 ± 0.64 years) were randomly assigned to one of two groups: CrossFit-based training (experimental, n = 10) and traditional training (control, n = 10). Baseline testing was conducted by the researcher and included tests for motor skills and general physical fitness domains including Sweden wall pull-ups and leg raises, push-ups, long jump, squats, burpees, shuttle run, and forward rolls. Judo-specific tests included O Soto Gari and O Goshi throws. CrossFit-based training was implemented twice per week for 15–20 min in the experimental group after usual training. The control group completed traditional methods of physical fitness training for judokas with the same training load regarding time. Experimental group participants significantly improved on leg raises (p < 0.01), push-ups (p < 0.05), and shuttle run (p < 0.001); the control group improved their shuttle run (p < 0.001). Only the experimental group improved on the O Soto Gari (p < 0.01) and O Goshi throws (p < 0.05). Results showed that the use of CrossFit-based trainings had a positive effect on 10–12-year-old judokas’ speed-strength abilities, speed-strength endurance, and muscular strength.

A generalizing formulation of the mathematical initial-boundary value problem on the propagation of an electroelastic three-component wave in a piezoelectric waveguide layer made of a material of arbitrary anisotropy is given. The initial-boundary-value mathematical problem of controlling the propagation of an electroelastic wave by surface electromechanical influences is reduced to a convergent system of problems of controlling the eigenfunctions and the corresponding eigen harmonics of the electromechanical characteristics of the propagating wave. Definitions of the precise controllability of a three-component electroelastic wave are given, as well as definitions of regulation by the localization of wave energy by electromechanical surface influences as a problem of optimal control of the distribution of a three-component electroelastic wave over the thickness of a piezoelectric waveguide. [ABSTRACT FROM AUTHOR]

Receptor for advanced glycation end products (RAGE) is involved in the pathogenesis of Alzheimer’s disease. We have previously revealed that RAGE fragment sequence (60–76) and its shortened analogs sequence (60–70) and (60–65) under intranasal insertion were able to restore memory and improve morphological and biochemical state of neurons in the brain of bulbectomized mice developing major AD features. In the current study, we have investigated the ability of RAGE peptide (60–76) and five shortened analogs to bind beta-amyloid (Aβ) 1–40 in an fluorescent titration test and show that all the RAGE fragments apart from one [sequence (65–76)] were able to bind Aβ in vitro. Moreover, we show that all RAGE fragments apart from the shortest one (60–62), were able to protect neuronal primary cultures from amyloid toxicity, by preventing the caspase 3 activation induced by Aβ 1–42. We have compared the data obtained in the present research with the previously published data in the animal model of AD, and offer a probable mechanism of neuroprotection of the RAGE peptide.

Copyright of Proceedings of the National Academy of Sciences of Armenia. Mechanics is the property of National Academy of Sciences of the Republic of Armenia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

For a system simulating the dynamics of a single-link electromechanical manipulator, the problem of constructing a control voltage and determining the areas of final states is solved, the transition to any point of which from the initial state of rest using the constructed control occurs in a finite time without violating the specified restrictions on the voltage and heat release power in the winding of the rotor of the electric motor. [ABSTRACT FROM AUTHOR]

We consider the limited control problem for the motion of a point gripper of a plane two-link manipulator with linear links of equal length, the second link being statically balanced. Regions are constructed on the plane of the generalized coordinates of the manipulator that allow, based on the specified coordinates of the manipulator's terminal position, to determine the controls that ensures the manipulator moves from the initial rest position to the specified terminal resting position in a finite time without violating the controls constraints, and also to select the type of final configuration in which the movement time is gripper is minimal. It is established by numerical calculations that the optimal choice of the final configuration can significantly reduce the motion time of the manipulqtor gripper. An estimate is given for the proximity of the results obtained using the considered control method and time-optimal control. [ABSTRACT FROM AUTHOR]

Copyright of Proceedings of the National Academy of Sciences of Armenia. Mechanics is the property of National Academy of Sciences of the Republic of Armenia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)