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Abstract A review is presented of the latest technologies for vertex detectors that can be used in experiments at the NICA collider. These technologies include both the novel pixel detectors with new ultralight radiation-transparent carbon composite structures and cooling systems. The efficiency of reconstructing D meson decay is estimated for the developed detector complexes, and the possibility of using these complexes to study the formation of clusters of cold, dense quark-gluon matter inside nuclei are studied.

Liver cancer remains a global challenge of healthcare, with the incidence growing worldwide. According to various authors, over 1 million patients will be diagnosed with liver cancer each year by 2025. The molecular pathogenesis of HCC varies with respect to genotoxic lesions and aetiologies. Although our understanding of the HCC pathophysiology and drivers tends to improve, it is still distant from translation into clinical practice. About 25 % of HCC cases are associated with variant mutations. HCC pathophysiology is a complex multi-step process. The interaction of various factors underlies the early stages of malignant hepatocyte transformation towards the development of HCC. Overall, about 20–25 % of HCC patients have at least one potential driver mutation. Obesity should also be noted as being associated with a higher risk of HCC and various other cancers. Despite many issues in the HCC pathogenesis being already known, the unresolved questions remain. Modern molecular genetic diagnostics and animal modelling of malignant tumours are expanding our horizons of knowledge in this field.

Introduction. Over the past two decades, a large amount of data has been accumulated that show the significant impact of social factors on the health of the population. The Republic of Bashkortostan is a large industrial centre and one of the most promising subjects of the Russian Federation. Purpose of the study. Ranking the territories of the Republic of Bashkortostan by priority socioeconomic indices, as well as determining their impact on the health of the child population. Material and methods. As the initial data, the materials of the socioeconomic state of the Republic of Bashkortostan, data on the number and morbidity of the child population for the period 2014-2018 were used. Correlation-regression analysis was carried out, and qualitative assessments of the results obtained were given. The principle of dividing the territory into seven socio-economic zones, taking into account climatic and geographical features, the development of industrial potential and the existing socio-economic ties, was chosen as the basis for the study. Results. The ranking of territories by socio-economic indices in the Republic of Bashkortostan showed that most of the municipalities (over 60%) have a low level of socio-economic development. The most favourable conditions in terms of social comfort for children were found in the southern, central and northwestern economic zones. So, as socio-economic indices improve by 2018, the incidence of the population tends to decrease. Conclusion. Thanks to the data obtained, a number of the most disadvantaged areas in socio-economic development and morbidity in the child population have been identified. In these territories, it is recommended to develop a set of measures to improve and stabilise socio-economic indices.

Introduction. The activities of enterprises engaged in the production, preparation, transportation and primary processing of oil are associated with the formation and accumulation of a large amount of waste (spent drilling fluids, drilling mud, oil sludge, spent catalysts, etc.), which leads to pollution of environmental objects and can contribute to the formation of adverse effects on public health. Materials and methods. The sanitary and hygienic state of atmospheric air, soil, the water of surface (rivers, lakes) and underground (wells, wells, springs) water sources, the water of centralized water supply systems in the territories of large oil fields the Republic of Bashkortostan is carried out. The origins of information were data from many years of in-house research, the regional information fund of the Sanitary Hygienic Monitoring, and departmental laboratories. Results. Studies have found that in areas of oil production, the content of chemicals in concentrations exceeding hygienic standards is detected: in the atmospheric air - dihydrosulfide, hydrocarbons, nitrogen dioxide, sulfur dioxide; in underground waters - chlorides, sulfates, nitrates, iron, strontium, increased mineralization and general hardness; in the soil - sulfates, chlorides, nitrates, petroleum products. Contamination of water from underground water sources and atmospheric air can contribute to the risk of adverse effects from individual organs and systems, as well as carcinogenic hazards. Based on the results of the study, ecological and hygienic recommendations were developed. Conclusion. As a result of the study, the level of public health risk associated with environmental factors in the oil-producing region was assessed, and a set of hygienic measures was justified.

The production of hadrons containing heavy quarks as well as the fragmentation of dense nuclear matter clusters accompanied by an increase in the yield of heavy flavor particles can be studied at the energies of colliding nuclei in the NICA collider. The concept of a vertex detector based on silicon pixel detectors was therefore developed for the effective registration of short-lived particles in the Multi-Purpose Detector (MPD) experiment at the NICA collider. Estimates of the main characteristics of this vertex detector are obtained.

Currently, polypropylene is one of the most common polymers in the world. Due to its resistance to high temperatures, strength and density, it has found very wide application in the field of medicine. Polypropylene produces medical devices, pharmaceutical packaging, containers, suture threads. But a special place is occupied by non-woven materials based on polypropylene: surgical underwear, surgical gowns. As you know, to sterilize these products using ionizing radiation, which is the most effective of all methods. However, it leads to the destruction of polypropylene, as a result of which its physical and mechanical properties deteriorate. It is also known that the dose of radiation can vary depending on the location of the product in the box. Thus, materials can be degraded to varying degrees depending on the location in the box from the electronic emitter. As the object of study was selected: PP 1562R polypropylene produced by OAO Nizhnekamskneftekhim. It has been established that the location of polypropylene samples upon irradiation has little effect on the degree of their destruction.

Introduction. Wastewater contaminated with oil, demulsifiers, hydrogen sulfide, ammonium sulfide, phenol, sulfates, aromatic hydrocarbons, alkali, fatty acids, various solutes, etc. is formed at oil refining and petrochemical enterprises. Runoff entering surface and underground water sources can harm water quality, sanitary conditions of life, and water use of the population. Taking this into account, further improvement of scientific approaches to ensure the safety of water bodies that are sources of drinking and recreational use, assessment, and prevention of public health risks caused by water factors is of particular importance. Material and methods. To assess the degree of influence of industrial enterprises on the quality of water sources, we studied the sanitary condition of the Belaya River and its tributaries, as well as underground water lying in the area of oil refining and petrochemical industries. The analysis of the water quality of surface and underground water sources according to the data of laboratory studies of departmental laboratories; the results of scientific and practical research and publications on the studied problem for 1999-2019. Results. Materials of observation data show that wastewater from changes of industrial enterprises the sanitary condition of surface reservoirs: there is a decrease in the content of ammonium nitrogen and biological oxygen consumption indices and a significant increase in the content of nitrates, chlorides, sulfates, and petroleum products. Surface water sources are characterized by unfavorable organoleptic characteristics, high organic pollution, and the presence of specific compounds (petroleum products, surfactants, alpha-methylstyrol, benzene, toluene, isopropylbenzene, and hydrogen sulfide) in concentrations higher than their hygiene regulations. Underground waters located on the territories of the main industrial complexes are characterized by high mineralization, extremely high hardness, high content of iron, nitrates, and petroleum products. Conclusion. Refineries and petrochemicals affect the pollution of surface and underground water sources. The water quality of the surveyed water bodies does not meet sanitary and hygienic standards. The priority indices of the influence of the enterprises of branch on water bodies include organoleptic indices of organic pollution indices of total salts composition of water, the content of specific ingredients: oil, benzene, toluene, isopropyl, alpha-methyl styrene, xylene, cresol, kerosene, gasoline, fuel oil, ethylene, propylene, 3,4-benzo(a)pyrene, phenols (volatile), methyl mercaptan, nonionic and anion-active surfactants, biological oxygen consumption indices and others. The research made it possible to assess the level of pollution of water bodies located in the zone of industrial enterprises and develop measures to reduce the man-made impact on the environment and public health.

The production of nonwovens over the past few years remains one of the most promising areas in the textile industry. This is due to the short cycle of production of such materials from raw materials to finished products and the ability to produce at a low cost a wide range of materials for both household and technical use. In particular, non-woven materials are widely used for the manufacture of disposable medical clothing and underwear. An important characteristic for surgical clothing is an indicator of bursting strength. This study simulates material deformation similar to elbow pressure when bending the arms or knee when bending the legs. Since the lower part of the sleeve of the product refers to the critical zone of the product, i.e. to the zone most likely to be involved in the transfer of infectious pathogens to or from the wound, the sterile product must have a significant margin of bursting strength. The effect of the absorbed dose of electronic radiation on the strength during the bursting strength of nonwoven medical material of SMS design with a surface density of 35 and 50 g/m2 obtained using the spanmelt technology was studied. It is shown that electronic radiation significantly reduces the resistance of the nonwoven to bursting strength. With an absorbed dose of 40 kGy, the material no longer meets the requirements for surgical clothing and linen by regulatory documents. For non-woven materials obtained using spanmelt technology, the bursting strength rate is even more sensitive to the action of ionizing radiation than the tensile tensile load, therefore, this indicator is recommended to be used as a characteristic indicator of radiation resistance.

Non-woven materials are widely used for the manufacture of disposable medical clothing and underwear. Radiation is widely used to sterilize single-use medical devices. The paper analyzes the effect of ionizing radiation at absorbed doses of 0-60 kGy on the stress-strain properties of medical non-woven spanmelt material based on polypropylene obtained by blow-molding technology. It has been established that ionizing radiation significantly reduces the breaking load and elongation in the machine and cross directions of the web. For this type of material, the most critical is the decrease in strength in the cross direction of the web, primarily because the level of strength in the cross direction of spanmelt materials is generally low. Sterilization by ionizing radiation further reduces strength and leads to the fact that non-woven materials irradiated with an absorbed dose of 50-60 kGy are close to unacceptable values in accordance with the requirements of EN 13975-2011.

The health of the population is closely linked to the social gradient: improving the quality of health is associated with improving the socio-economic situation of the country. The level and quality of life is one of the fundamental indicators of the country’s economic development. The Republic of Bashkortostan is a leading agrarian and industrial region and makes a significant contribution to the development of the country. There are no studies on a comprehensive assessment of socio-economic factors in the Republic of Bashkortostan. To carry out the study, the following data were used: total morbidity and number of children, materials of the Federal Information Fund for Social and Hygienic Monitoring data for a block of socio-economic indicators for 2014–2018 The relationship of socioeconomic indicators and the incidence of the child population was carried out using correlation and regression analysis. General analysis of the socio-economic situation of the Republic of Bashkortostan for the period 2014–2018. indicates a stable economic situation and positive dynamics indicators. The results of the influence of priority socio-economic factors on the health of the child population living in urban and rural settlements are obtained. For children living in cities of the Republic of Bashkortostan, the leading socio-economic indicators affecting the overall incidence were 7 indicators: educational expenses; percentage of apartments that do not have running water; the proportion of living space equipped with central heating; monthly average nominal accrued wages of workers in the economy; investment in fixed assets per capita; number of doctors of all specialties; the number of doctors in outpatient medical institutions. The incidence of children living in rural areas was revealed by the influence of 2 indicators: the average monthly nominal accrued wages of workers in the economy and investment in fixed assets per capita. The countryside of the region is lagging behind in most indicators compared to cities. The results of the study must be used to improve the regional development strategy, as well as minimize the impact of these indicators on the health of both children and the population as a whole.

Introduction. Operation of enterprises of petrochemical and oil refining industries is accompanied by significant pollution of air, soil, underground and surface water sources with a complex of toxic chemical compounds, which in turn has an adverse impact on the health and living conditions of the population. In order to carry out a correct assessment of the ecological and hygienic situation and reduce the risk to public health in regions with developed petrochemistry and oil refining, there is a need to optimize the existing mechanism of sanitary and epidemiological supervision of the quality of environmental facilities, to develop effective hygienic recommendations and targeted measures to reduce the level of anthropogenic impact and to prevent poor living conditions. Material and methods. The analysis of quality of objects of the environment according to departmental laboratories in territories of placement of the enterprises of petrochemistry and oil refining for 2007-2018 is carried out; results of scientific and practical researches and publications on the studied problem for 2004-2017. Results. There are identified the major sources and reasons for the admission of harmful chemical substances in the environmental objects from the petrochemical and refining industries. The most part of the enterprises of branch was established to operate for a long time, the outdated equipment, the power-consuming while there are used imperfect technologies characterized by insignificant depth of processing of raw materials and representing danger of ecological risk for objects of the environment. The list of priority indices recommended for the control of atmospheric air, soil, water bodies in the areas of petrochemistry and oil refining is based on. Developed and tested an algorithm of assessment of environmental quality and the health risk of the population in the territories with developed petrochemical industry and oil refining. On the basis of the obtained results, approaches to the development of hygienic recommendations and targeted measures to reduce the tested man-made load of the territories are proposed. Conclusion. The proposed methodological approaches will optimize the assessment of an ecological and hygienic situation, develop preventive measures to reduce the level of man-made impact and prevent poor living conditions in regions with developed petrochemistry and oil refining.

While producing polymers as well as during their processing, a certain amount of stabilizers is introduced into the product, which should ensure polymer properties saving during processing and those of polymer products during storage and operation. However, in cases where medical products based on polypropylene are subjected to radiation sterilization, there are not enough stabilizers in it to save their characteristics during operation. In this regard, we made an assessment of the influence of processing conditions on the properties of polypropylene with a different set of stabilizers in the manufacture of products based on it, in order to assess the degree of influence of each technological operation, including the effects of ionizing radiation during sterilization. Processing and radiation exposure are shown to affect the properties of polypropylene. Nevertheless, the effect of ionizing radiation with an absorbed dose of 40-60 kGy exceeds the negative effect of thermo-oxidative breakdown greatly during the extrusion of PP. Polypropylene containing organophosphorus stabilizers (brand PP 1562R) is more susceptible to breakdown. This is indicated by low values of oxidation induction time, breakdown initial temperature, as well as high values of MFI after exposure to electron radiation. PP brand PP H350FF/1 whose stabilizing complex contains phenol-phosphite antioxidants is more resistant to breakdown during processing and sterilization. For both brands under study, it is apparently necessary to increase the content of stabilizing additives in order to save the properties at the level of the original unexposed material.

Different cytokines are believed to play an important role in the pathogenesis of juvenile idiopathic arthritis (JIA). Some of them may serve as the prognostic markers for the disease severity, the eye lesion, and the effectiveness of therapy in JIA patients. To evaluate the serum concentration of TNFα, IL1β, IL6 and IL10, their spontaneous and mitogen-induced production levels in the whole blood cell culture of JIA patients and to correlate these indicators with the disease features and with the effectiveness of methotrexate therapy. Twentyeight Russian patients with JIA, naive for disease-modifying antirheumatic drugs, were enrolled in the study. The serum levels of cytokines (TNFα, IL1β, IL6, and IL10); the levels of their spontaneous and mitogen-induced production in the whole blood cell culture were studied by solid-phase enzyme immunoassay. The serum levels and spontaneous production levels of TNFα, IL1β, IL10 were low in JIA patients. The levels of TNFα, IL1β, IL6, IL10 in mitogen-induced production were significantly higher than those in spontaneous production (pcor0,05). The association of some clinical features (disease duration, uveitis, elevated ESR, hyperimmunoglobulinemia M with the cytokines (TNFα, IL6, and IL10) levels was established in JIA. The most promising is the association between the uveitis in JIA patients and an increase of spontaneous IL6 production (pcor=0,004), as well as a decrease of mitogen-induced TNFα production (pcor=0,029) in the whole blood cell culture. Statistically significant associations with a response to methotrexate therapy and disease severity in JIA patients were not observed. As a result of studying levels of cytokines (TNFα, IL1β, IL6, and IL10) in JIA patients, the relationship of TNFα, IL6 and IL10 was established with the number of clinical manifestations of the disease. If confirmed in larger samples, the study of the spontaneous IL6 production in the whole blood cell culture might be used for the early diagnosis of the uveitis in JIA patients.

For polymeric materials intended for the manufacture of disposable sterile medical devices, resistance to sterilization methods is important. For the manufacture of disposable medical products is widely used polypropylene, destructive during radiation sterilization. It is established that the addition of polyquinone leads to a decrease in the destruction of polypropylene, which is manifested in a decrease in the values of the melt flow index and an increase in the degradation temperature of polypropylene of the irradiated compositions.

Using optical and atomic-force microscopy methods, it has been established that exposure to electron radiation causes a change in the supramolecular structure of polypropylene – in films obtained by recrystallization of irradiated polypropylene, spherulites have a less perfect shape than films obtained from unirradiated polypropylene. Also, the films obtained by recrystallization of irradiated polypropylene surface roughness is greater.

The authors reviewed the functions of strategic planning and identified problems in the development of urban passenger transport services. They identified the impact of land use on public transport development. Scientific studies of regions and cities have determined a number of conditions for their economic growth in the post-industrial economy, which include the importance of agglomerations and clusters, the differentiation and specialization of economic activities, the development of services and infrastructure. Increasing employment, the development of regional and municipal innovation systems, the ability of cities and regions to be attractive for living and creative fruitful work are increasingly important for the socio-economic development of cities. One important consequence of the research is that economic transformation towards regional and urban growth and development is becoming increasingly dependent on dense physical space. All these conditions can be realized with the availability of efficient and high-quality transportation services, vehicles and infrastructure, increased mobility of the population and accessibility of the services provided. This, in turn, means that public transport is the driving force for the economic development of regions and municipalities in terms of mobility and accessibility in general, as well as in comparison with other modes of transport.

The effect of low-pressure high-frequency (HF) plasma treatment on the structure of the materials formed by bundles of natural protein (collagen) fibers is considered. The outer surface of the material is being affected by a constant flow of ions and a pulse-periodic flow of electrons. During this procedure the electrons flow at opposite sides of the sample in antiphase. This leads to that an alternating electric field is created, which intensity is estimated approximately at 105 V/m, inside the material. As a result, in the capillaries and pores, a breakdown occurs and charged particles are forming during this process. The recombination of these particles releases an energy of 15.76 eV on the surface of pores and capillaries, which is transferring to the surface molecules of the protein, which leads to the bulk modification of the material based on protein fibers. Such volumetric processing provides an effective modification of structural elements, allowing you to significantly improve the quality of liquid treatments in the production of collagen-containing materials and their properties in general.

Mediation is a process that aims to resolve disputes with the assistance of the mediator on the basis of the voluntary agreement of the parties with a view to reaching a mutually acceptable solution. The mediation skills are considered the key to successful resolution of corporate conflicts and labor conflicts that have arisen both inside and outside the organization in the developed countries. The success of mediation procedure depends on the qualification of the mediator. This article investigates key points and criteria of identifying the development of mediator competences. The purpose of this work is analysis of criteria and standards for determining the professional competencies of a mediator. The study has been conducted using statistical, mathematical, expert evaluation methods and legal methodology tools. The mediator competencies model has been created. Scientific gaps in the area of tools for assessing the mediation competence have been revealed, as well as the need for further scientific study of the mediator professional qualities assessment. The research results can be used in studying the mediation procedure.

The globalization taking place in modern conditions permeates all the structural elements of the world economy, leading them to competitive confrontation. Globalization overcomes economic barriers, promotes the growth of trade associations, and previously closed sectors of the economy makes it accessible for international competition. Nowadays, it is difficult to overestimate the importance of the services market in the economy not only of a single state, but also in conditions of international socio-economic relations. In today's world, services are becoming increasingly popular. Many people are willing to pay a lot to have windows installed, the stove repaired, and even screwed in a light bulb. There are several views on the development of services. One of them fully supports the fact that services have replaced work in many areas. Thus, unemployment can be reduced. Since there is someone to perform each service who will perform it for a certain amount, thereby ensuring wages for himself. Services have their pros and cons, while their number is growing every year. According to the statistics of the Russian Federation, in recent years, the share of intangible production in the structure of GDP has been steadily increasing, the employment rate in the provision of services is also actively growing every year, which indicates an increase in population demand for the consumption of various services. The article presents a study of the impact of globalization on the service sector. The factors determining the development of the service economy are determined.

The relevance of the chosen research topic is due to the current state of the market and the ever-increasing requirements for companies. Modern organizations must remain stable, successful and competitive. Crowdsourcing is one way to optimize the functioning of enterprises. Currently, crowdsourcing is being introduced into many areas of human life: business, art, medicine, science, etc. However, the issues of using crowdsourcing in the scientific literature have not been fully studied, which reflects the importance of the chosen research topic. In this study, the relationship of two modern management techniques was determined: outsourcing and crowdsourcing, which is shown as a logical extension of one management tool from another, the author defines the definition of outsourcing. The novelty of the study is reflected in the results of a comparative analysis of outsourcing and crowdsourcing. The author identifies related signs and differences, for each distinguishing feature a characteristic is given that reflects the specifics of using each of the ways to optimize the enterprise. The existing definitions of crowdsourcing were analyzed and their own author's definition was given. This study presents the mechanism of a crowdsourcing project, and its participants are identified. As a result of the study, the advantages of using crowdsourcing were revealed both for large companies and small and medium enterprises, as well as for participants in crowdsourcing projects themselves. This study expands knowledge about the nature, value and benefits of crowdsourcing in enterprises in order to increase competitiveness and optimize their functioning.

As a result of the evaluation of the indicators of a large fishing enterprise of the Volga-Caspian basin (carrying out extraction and processing of biological resources), proposals were presented to reduce the value of the property and sources of financing of the organization, and this decrease was generally balanced with changes in revenue and profit of the enterprise. Considering the results of the analysis, as well as external and internal factors of the organization’s functioning, it is recommended to create a planning system to ensure financial stability in subsequent periods. Implementation is possible with the organization of the budgeting process. A stock management strategy was proposed to optimize their volume and structure. ABC analysis was used for this purpose, which made it possible to strengthen control over the main types of stocks and improve management efficiency. The proposed measures will facilitate the release of funds and contribute to the stabilization of the financial condition of the enterprise.

The analysis in the centralized laboratory is the main model of laboratory diagnosis and monitoring in the conditions of intensive care. However, alternative models of “point-of-care testing” technology are being actively introduced nowadays. This review article presents the analysis of “Point-of-care testing” technologies from the perspective of the intensive care doctor. The main advantages of this monitoring idea include the speed of analysis and the cost of components. Among the disadvantages we can identify ambiguous assessment of the accuracy and objectivity of analyses, additional burden on the staff of resuscitation and intensive care units. Possible ways of resolving disputable issues aimed at improving quality and reproducibility of the analyses are outlined in this work. Despite the fact that currently “Point-of-care testing” technologies cannot replace centralized laboratories, they are steadily occupying a certain niche and are going to play a more important role in diagnosing and monitoring patients in critical condition.

This research is to assess the efficiency of canned vegetables production. In order to plan the production activities a wide range of parameters is analyzed, for instance the costs production, profit, market, finance, taxation system and political situation. However, the assessment of these parameters is necessary with reference to a specific aims and tasks. The specific time or period, which those parameters are assessed within, is also important. Here the process of launching into production of 2 kinds of canned vegetables on a new production line is considered. The assessment of production efficiency is given on the base of Net Present Value (NPV), internal rate of return (IRR), productivity index. The obtained data proves the expediency of the project; its implementation will increase the economic stability of the enterprise.

Free radicals have taken a firm place among the explanatory principles of the onset and development of tumors. Unambiguous ideas about the role of these highly active agents in carcinogenesis have not yet been obtained. The experimental results are contradictory, often the opposite. The field of study of the value of the activity of antioxidant systems based on the results obtained is no less controversial. In this regard, the urgent problem is the need to prescribe antioxidants in oncology. Antitumor effects of antioxidants are being questioned in many works, which brings to the forefront the appropriateness and adequacy of their appointment. The ambiguous role of free radicals in carcinogenesis determines the development of therapeutic strategies based on the precise modulation of oxidative processes.

The article analyzed the incidence of gastric cancer in the Republic of Bashkortostan from 1993 to 2002 and from 2003 to 2012. A comparative analysis of cancer incidence rates of primary tumors of the stomach, obtained regularities level dynamics of disease in different years, depending on age and gender.

The article analyzes the results of a randomized multicenter studies devoted to elucidate the role of adjuvant and neoadjuvant chemotherapy, targeted therapy, adjuvant chemoradiation therapy in improving the results of surgical treatment of gastric cancer.

In the article are the incidence of breast cancer, cervical and ovarian cancer in the Republic of Bashkortostan from 1993 to 2002 and from 2003 to 2012 analyzed. A comparative analysis of the performance of the primary cancer incidence neoplasms of the female reproductive system has done, level patterns the dynamics of disease in different years, depending on age are obtained.

The article analyzes the incidence of prostate cancer in the Republic of Bashkortostan from 1993 to 2002 and from 2003 to 2012, the levels of the primary disease, the patterns of the level, dynamics of morbidity in different years depending on age.

The article summarizes the experience of academic and pedagogical leading of universities in Russia to train specialists of new formation in oncology, in accordance with the challenges of modern society and the needs of the modernized health. There are prospects and the possibility of the introduction of advanced educational technology in health professional education on the basis of the competence approach. The modern model of continuing professional development is implemented in the departments of oncology leading Russian universities.

A research purpose - development of conceptual provisions and development of practical recommendations about assessment and improvement of quality of services of city public transport in digital economies. Implementation of an effective objective of a research demanded the solution of the following tasks: determinations of tendencies of forming of urban transport environment; identifications of problems and perspectives of development of services of city public transport; analysis of a state and development of system of public transport; formations of system of indicators of sustainable development of public transport; developments of methodical approaches to determination of service quality of city public transport; quality evaluations of services of transportation and service on city bus transport; developments of actions of the strategic plan of improvement of quality of services of public transport. Object of a research are such subjects of system of public transport as transport operators, consumers of services (passengers), bodies of the public and municipal administration. Research questions are organizational and economic relations developing in the course of rendering services of city public transport.

The article deals with the essential characteristics of the willingness of contract managers to professional activities in the procurement system, the possibility of their change in the learning process and some challenges connected from educational values’ influence point of view. The purpose of this article is consideration of the existing approaches to understanding of the phenomenon of contract managers’ training from the point of view of value orientations, which are the basis for business activity in conditions of innovative development of the global economy. The results of the conducted research on the readiness to changes in procurement are presented in the study. They characterize the economic and social environment in procurement in Russia at present and in Samara region of the Russian Federation, exactly. Readiness to changes is crucial for creation of a new mode of thinking of the modern business community. By results of the conducted research, the authors offered a model of this integrative characteristic, which can be the basis for purposeful process of training and retraining of contract managers for development of the procurement and, furthermore, economics of the region and country in the context of requirements of the innovative economy.