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Recently, the use of drospirenone-containing microdosed hormonal contraceptives containing folates has come at an opportune time. The common use of these contraceptives is associated with not only high efficacy and acceptability, but also with a positive effect on the symptoms of premenstrual syndrome, which is mediated by impact on the central nervous system. Drospirenonecontaining COCs are also known as products leading to a reduction in sebum excretion rates, which makes it possible to use them in acne therapy. Metafolin as part of microdosed hormonal contraceptive Yaz® plus compensates for the folate concentration required to prevent neural tube defects in the fetus in 27–30 days of pregnancy to some extent. Consequently, the use of drospirenone-containing hormonal contraceptives with folates provides not only a contraceptive, but also a therapeutic effect when fluid is retained in the body tissues. Thus, Yaz® plus product is indicated for use not only for contraceptive, but also for therapeutic purposes, as indicated in the patient information leaflet.

Inflammatory pelvic diseases (IPD) are associated with increased incidence of sexually transmitted infections. The modern features of the PID course raise the question of including drugs improving therapy outcomes in the combination PID therapy. The development of chronic inflammatory processes is accompanied by changes in the body’s immune system, which serves as a basis for developing and finding new therapeutic agents and methods that have an effective therapeutic effect aimed at restoring the function of the impaired human immune status as a whole. The synthetic low molecular weight immunomodulating drug with anti-inflammatory activity aminodihydrophthalazinedione sodium possesses the above described therapeutic potential.

Menorrhagia is the pathological condition which is negatively affecting physical, emotional and social quality life of the woman. Medicines of the choice of therapy of uterine bleedings are the combined oral contraceptives (COC). The estradiol valerate/ dienogest (E2V/DNG), represents the combined oral contraceptive (COC) recommended for women as contraceptive. Gives to feature of influence of medicine on endometrium the chance of its application in case of uterine bleedings. The hormones which are a part suppress excessive proliferation of endometrium that leads to reduction of amount of menstrual allocations. Results of a research which confirm successful application of E2V/DNG in case of the menorrhagia at the women of reproductive age in clinical situations who aren’t requiring operational treatment are provided.

Menstrual irregularities are an eternal female problem, in the treatment of which ever new aspects are opening. One of the most common problems is pain in the abdomen during menstruation. This form of menstrual disorder requires special attention, since, according to different authors, menstrual cramps of various severity are registered by 30 to 75% of women. However, about 10% of women, along with sharp pain, speak about deterioration of the general condition to the extent of temporary disability. Moreover, it is known that pain affects the emotional sphere, mental and general condition of the woman, and as a consequence, the relations within the family, thus making it a relevant healthcare and social problem (Smetnik V.P., Tumilovich L.P., 1998).

In recent years viral infections take the worldwide leading place due to their damaging effect on the body in general and reproductive system in particular. Herpes infection is a serious medico-social problem, which is one of the most common human viral infections. More than 90% of the population worldwide are infected with one or more serotypes of the herpes virus. Recurrent herpes virus diseases affects 2--12% of the population.

The data on managing patients with vulvovaginal atrophy and abnormal cytological results are provided for obstetrician-gynecologists.

The article presents modern literature data on emergency contraceptive methods and the principles of the action of drugs used for this purpose, their characteristics, effects on the reproductive system, efficacy, acceptability, their effect on ovulation and the state of the endometrium.

Magnesium is one of the most important trace elements necessary for the life of the human body. It supports the normal exchange of proteins and nucleic acids (DNA and RNA), reduces spasm of the arteries, both peripheral and coronary, prevents the formation of blood clots, relaxes the uterus with hypertension, restores heart rhythm with tachycardia, contributes to the normal course of pregnancy, etc. Magnesium deficiency has a negative impact on health, especially in women in the menopause. Hypomagnesemia exacerbates the course of the main clinical manifestations and conditions characteristic of climacteric syndrome, and therefore the use of magnesium preparations in this category of patients will improve their health and quality of life.

This review of literature is devoted to the study of highly selective progestogen of the last generation - nomegestrol acetate. Showing its high antigonadotropic effect, as well as selective effect on the progesterone receptors, and low binding to other receptors, which results in a low incidence of side effects. No less significant are the high contraceptive efficacy, acceptability and lack of influence on the parameters of hemostasis, blood lipid profile, mammary glands.