542 results on '"A. Müllers"'
Search Results
2. Normoglycemia and physiological cortisone level maintain glucose homeostasis in a pancreas-liver microphysiological system
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Sophie Rigal, Belén Casas, Kajsa P. Kanebratt, Charlotte Wennberg Huldt, Lisa U. Magnusson, Erik Müllers, Fredrik Karlsson, Maryam Clausen, Sara F. Hansson, Louise Leonard, Jonathan Cairns, Rasmus Jansson Löfmark, Carina Ämmälä, Uwe Marx, Peter Gennemark, Gunnar Cedersund, Tommy B. Andersson, and Liisa K. Vilén
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Biology (General) ,QH301-705.5 - Abstract
Abstract Current research on metabolic disorders and diabetes relies on animal models because multi-organ diseases cannot be well studied with standard in vitro assays. Here, we have connected cell models of key metabolic organs, the pancreas and liver, on a microfluidic chip to enable diabetes research in a human-based in vitro system. Aided by mechanistic mathematical modeling, we demonstrate that hyperglycemia and high cortisone concentration induce glucose dysregulation in the pancreas-liver microphysiological system (MPS), mimicking a diabetic phenotype seen in patients with glucocorticoid-induced diabetes. In this diseased condition, the pancreas-liver MPS displays beta-cell dysfunction, steatosis, elevated ketone-body secretion, increased glycogen storage, and upregulated gluconeogenic gene expression. Conversely, a physiological culture condition maintains glucose tolerance and beta-cell function. This method was reproducible in two laboratories and was effective in multiple pancreatic islet donors. The model also provides a platform to identify new therapeutic proteins, as demonstrated with a combined transcriptome and proteome analysis.
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- 2024
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3. The new APD-Based Readout of the Crystal Barrel Calorimeter -- An Overview
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Collaboration, CBELSA/TAPS, Honisch, C., Klassen, P., Müllers, J., Urban, M., Afzal, F., Bieling, J., Ciupka, S., Hartmann, J., Hoffmeister, P., Lang, M., Schaab, D., Schmidt, C., Steinacher, M., Walther, D., Beck, R., Brinkmann, K. -T., Crede, V., Dutz, H., Elsner, D., Erni, W., Fix, E., Frommberger, F., Grüner, M., Jude, T., Kalischewski, F., Keshelashvili, I., Krönert, P., Krusche, B., Mahlberg, P., Metag, V., Meyer, W., Müller, F., Nanova, M., Otto, B., Richter, L., Runkel, S., Salisbury, B., Schmieden, H., Schultes, J., Seifen, T., Stausberg, N., Taubert, F., Thiel, A., Thoma, U., Urff, G., Wendel, C., Wiedner, U., Wunderlich, Y., and Zaunick, H. -G.
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Physics - Instrumentation and Detectors ,Nuclear Experiment - Abstract
The Crystal Barrel is an electromagnetic calorimeter consisting of 1380 CsI(Tl) scintillators, and is currently installed at the CBELSA/TAPS experiment where it is used to detect decay products from photoproduction of mesons. The readout of the Crystal Barrel has been upgraded in order to integrate the detector into the first level of the trigger and to increase its sensitivity for neutral final states. The new readout uses avalanche photodiodes in the front-end and a dual back-end with branches optimized for energy and time measurement, respectively. An FPGA-based cluster finder processes the whole hit pattern within less than 100 ns. The important downside of APDs -- the temperature dependence of their gain -- is handled with a temperature stabilization and a compensating bias voltage supply. Additionally, a light pulser system allows the APDs' gains to be measured during beamtimes.
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- 2022
4. Metadata-guided Consistency Learning for High Content Images
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Haslum, Johan Fredin, Matsoukas, Christos, Leuchowius, Karl-Johan, Müllers, Erik, and Smith, Kevin
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Computer Science - Computer Vision and Pattern Recognition - Abstract
High content imaging assays can capture rich phenotypic response data for large sets of compound treatments, aiding in the characterization and discovery of novel drugs. However, extracting representative features from high content images that can capture subtle nuances in phenotypes remains challenging. The lack of high-quality labels makes it difficult to achieve satisfactory results with supervised deep learning. Self-Supervised learning methods have shown great success on natural images, and offer an attractive alternative also to microscopy images. However, we find that self-supervised learning techniques underperform on high content imaging assays. One challenge is the undesirable domain shifts present in the data known as batch effects, which are caused by biological noise or uncontrolled experimental conditions. To this end, we introduce Cross-Domain Consistency Learning (CDCL), a self-supervised approach that is able to learn in the presence of batch effects. CDCL enforces the learning of biological similarities while disregarding undesirable batch-specific signals, leading to more useful and versatile representations. These features are organised according to their morphological changes and are more useful for downstream tasks -- such as distinguishing treatments and mechanism of action.
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- 2022
5. Cell Painting-based bioactivity prediction boosts high-throughput screening hit-rates and compound diversity
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Johan Fredin Haslum, Charles-Hugues Lardeau, Johan Karlsson, Riku Turkki, Karl-Johan Leuchowius, Kevin Smith, and Erik Müllers
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Science - Abstract
Abstract Identifying active compounds for a target is a time- and resource-intensive task in early drug discovery. Accurate bioactivity prediction using morphological profiles could streamline the process, enabling smaller, more focused compound screens. We investigate the potential of deep learning on unrefined single-concentration activity readouts and Cell Painting data, to predict compound activity across 140 diverse assays. We observe an average ROC-AUC of 0.744 ± 0.108 with 62% of assays achieving ≥0.7, 30% ≥0.8, and 7% ≥0.9. In many cases, the high prediction performance can be achieved using only brightfield images instead of multichannel fluorescence images. A comprehensive analysis shows that Cell Painting-based bioactivity prediction is robust across assay types, technologies, and target classes, with cell-based assays and kinase targets being particularly well-suited for prediction. Experimental validation confirms the enrichment of active compounds. Our findings indicate that models trained on Cell Painting data, combined with a small set of single-concentration data points, can reliably predict the activity of a compound library across diverse targets and assays while maintaining high hit rates and scaffold diversity. This approach has the potential to reduce the size of screening campaigns, saving time and resources, and enabling primary screening with more complex assays.
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- 2024
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6. Polarization observables in double neutral pion photoproduction
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Collaboration, CBELSA/TAPS, Seifen, T., Hartmann, J., Afzal, F., Anisovich, A. V., Beck, R., Becker, M., Berlin, A., Bichow, M., Brinkmann, K. -Th., Crede, V., Dieterle, M., Dutz, H., Eberhardt, H., Elsner, D., Fornet-Ponse, K., Friedrich, St., Frommberger, F., Funke, Ch., Gottschall, M., Grüner, M., Görtz, St., Gutz, E., Hammann, Ch., Hannappel, J., Herick, J., Hillert, W., Hoffmeister, Ph., Honisch, Ch., Jahn, O., Jude, T., Käser, A., Kaiser, D., Kalinowsky, H., Kalischewski, F., Klassen, P., Keshelashvili, I., Klein, F., Klempt, E., Koop, K., Krusche, B., Lang, M., Mahlberg, Ph., Makonyi, K., Messi, F., Metag, V., Meyer, W., Müller, J., Müllers, J., Nanova, M., Nikonov, K., Nikonov, V. A., Novotny, R., Reeve, S., Roth, B., Reicherz, G., Rostomyan, T., Runkel, St., Sarantsev, A. V., Schmidt, Ch., Schmieden, H., Schmitz, R., Schultes, J., Sokhoyan, V., Stausberg, N., Thiel, A., Thoma, U., Urban, M., Urff, G., van Pee, H., Walther, D., Wendel, Ch., Wiedner, U., Wilson, A., Witthauer, L., and Wunderlich, Y.
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Nuclear Experiment - Abstract
Measurements of target asymmetries and double-polarization observables for the reaction $\gamma p\to p\pi^0\pi^0$ are reported. The data were taken with the CBELSA/TAPS experiment at the ELSA facility (Bonn University) using the Bonn frozen-spin butanol (C$_4$H$_9$OH) target, which provided transversely polarized protons. Linearly polarized photons were produced via bremsstrahlung off a diamond crystal. The data cover the photon energy range from $E_{\gamma}$=650 MeV to $E_{\gamma}$=2600 MeV and nearly the complete angular range. The results have been included in the BnGa partial wave analysis. Experimental results and the fit agree very well. Observed systematic differences in the branching ratios for decays of $N^*$ and $\Delta^*$ resonances are attributed to the internal structure of these excited nucleon states. Resonances which can be assigned to SU(6)$\times$O(3) two-oscillator configurations show larger branching ratios to intermediate states with non-zero intrinsic orbital angular momenta than resonances assigned to one-oscillator configurations., Comment: 21 pages, 27 figures
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- 2022
7. Observation of a structure in the M$_{p\eta}$ invariant mass distribution near 1700 MeV/$c^2$ in the $\mathbf{\gamma p \rightarrow p \pi^0 \eta} $ reaction
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Metag, V., Nanova, M., Hartmann, J., Mahlberg, P., Afzal, F., Bartels, C., Bayadilov, D., Beck, R., Becker, M., Blanke, E., Brinkmann, K. -T., Ciupka, S., Crede, V., Dieterle, M., Dutz, H., Elsner, D., Frommberger, F., Gridnev, A., Gottschall, M., Grüner, M., Hammann, Ch., Hannappel, J., Hillert, W., Hoff, J., Hoffmeister, Ph., Honisch, Ch., Jude, T., Kalinowsky, H., Kalischewski, F., Keshelashvili, I., Ketzer, B., Klassen, P., Klein, F., Koop, K., Kroenert, P., Krusche, B., Lang, M., Lopatin, I., Messi, F., Meyer, W., Mitlasóczky, B., Müller, J., Müllers, J., Nikonov, V., Novinsky, V., Novotny, R., Piontek, D., Reicherz, G., Richter, L., Rostomyan, T., Runkel, S., Salisbury, B., Sarantsev, A., Schaab, D., Schmidt, Ch., Schmieden, H., Schultes, J., Seifen, T., Sokhoyan, V., Sowa, C., Spieker, K., Stausberg, N., Thiel, A., Thoma, U., Triffterer, T., Urban, M., Urff, G., van Pee, H., Wagner, M., Walther, D., Wendel, Ch., Werthmüller, D., Wiedner, U., Wilson, A., Winnebeck, A., Witthauer, L., and Wunderlich, Y.
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Nuclear Experiment ,Nuclear Theory - Abstract
The reaction $\gamma p \rightarrow p \pi^0 \eta$ has been studied with the CBELSA/TAPS detector at the electron stretcher accelerator ELSA in Bonn for incident photon energies from threshold up to 3.1 GeV. This paper has been motivated by the recently claimed observation of a narrow structure in the M$_{N\eta}$ invariant mass distribution at a mass of 1678 MeV/$c^2$. The existence of this structure cannot be confirmed in the present work. Instead, for E$_{\gamma}$ = 1400 - 1500 MeV and the cut M$_{p\pi^0} \le 1190 $ MeV/$c^2$ a statistically significant structure in the M$_{p\eta}$ invariant mass distribution near 1700 MeV/$c^2$ is observed with a width of $\Gamma\approx 35$ MeV/$c^2$ while the mass resolution is $\sigma_{res}$ = 5 MeV/$c^2$. Increasing the incident photon energy from 1420 to 1540 MeV this structure shifts in mass from $\approx$ 1700MeV/c$^2$ to $\approx$ 1725 MeV/$c^2$; the width increases to about 50 MeV/$c^2$ and decreases thereafter. The cross section associated with this structure reaches a maximum of $\approx$ 100 nb around E$_{\gamma} \approx$ 1490 MeV (W $\approx $ 1920 MeV), which coincides with the $p a_0$ threshold. Three scenarios are discussed which might be the origin of this structure in the M$_{p\eta}$ invariant mass distribution. The most likely interpretation is that it is due to a triangular singularity in the $\gamma p \rightarrow p a_0 \rightarrow p \pi^0 \eta$ reaction, Comment: 16 pages, 18 figure
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- 2021
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8. Telemedicine decision-making in primary care during the COVID-19 pandemic: Balancing patient agency and provider expertise
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Muellers, Kimberly A., Andreadis, Katerina, Mkuu, Rahma S., Lin, Jenny J., Horowitz, Carol R., Kaushal, Rainu, and Ancker, Jessica S.
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- 2024
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9. PANDA Phase One
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Barucca, G., Davì, F., Lancioni, G., Mengucci, P., Montalto, L., Natali, P. P., Paone, N., Rinaldi, D., Scalise, L., Krusche, B., Steinacher, M., Liu, Z., Liu, C., Liu, B., Shen, X., Sun, S., Zhao, G., Zhao, J., Albrecht, M., Alkakhi, W., Bökelmann, S., Coen, S., Feldbauer, F., Fink, M., Frech, J., Freudenreich, V., Fritsch, M., Grochowski, J., Hagdorn, R., Heinsius, F. H., Held, T., Holtmann, T., Keshk, I., Koch, H., Kopf, B., Kümmel, M., Küßner, M., Li, J., Linzen, L., Maldaner, S., Oppotsch, J., Pankonin, S., Pelizäus, M., Pflüger, S., Reher, J., Reicherz, G., Schnier, C., Steinke, M., Triffterer, T., Wenzel, C., Wiedner, U., Denizli, H., Er, N., Keskin, U., Yerlikaya, S., Yilmaz, A., Beck, R., Chauhan, V., Hammann, C., Hartmann, J., Ketzer, B., Müllers, J., Salisbury, B., Schmidt, C., Thoma, U., Urban, M., Bianconi, A., Bragadireanu, M., Pantea, D., Rimjaem, S., Domagala, M., Filo, G., Lisowski, E., Lisowski, F., Michałek, M., Poznański, P., Płażek, J., Korcyl, K., Lebiedowicz, P., Pysz, K., Schäfer, W., Szczurek, A., Firlej, M., Fiutowski, T., Idzik, M., Moron, J., Swientek, K., Terlecki, P., Korcyl, G., Lalik, R., Malige, A., Moskal, P., Nowakowski, K., Przygoda, W., Rathod, N., Salabura, P., Smyrski, J., Augustin, I., Böhm, R., Lehmann, I., Schmitt, L., Varentsov, V., Al-Turany, M., Belias, A., Deppe, H., Dzhygadlo, R., Flemming, H., Gerhardt, A., Götzen, K., Heinz, A., Jiang, P., Karabowicz, R., Koch, S., Kurilla, U., Lehmann, D., Lühning, J., Lynen, U., Orth, H., Peters, K., Ritman, J., Schepers, G., Schmidt, C. J., Schwarz, C., Schwiening, J., Täschner, A., Traxler, M., Voss, B., Wieczorek, P., Abazov, V., Alexeev, G., Barabanov, M. Yu., Dodokhov, V. Kh., Efremov, A., Fechtchenko, A., Galoyan, A., Golovanov, G., Koshurnikov, E. K., Lobanov, Y. Yu., Olshevskiy, A. G., Piskun, A. A., Samartsev, A., Shimanski, S., Skachkov, N. B., Skachkova, A. N., Strokovsky, E. A., Tokmenin, V., Uzhinsky, V., Verkheev, A., Vodopianov, A., Zhuravlev, N. I., Watts, D., Böhm, M., Eyrich, W., Lehmann, A., Miehling, D., Pfaffinger, M., Seth, K., Xiao, T., Ali, A., Hamdi, A., Himmelreich, M., Krebs, M., Nakhoul, S., Nerling, F., Gianotti, P., Lucherini, V., Bracco, G., Bodenschatz, S., Brinkmann, K. T., Brück, L., Diehl, S., Dormenev, V., Düren, M., Erlen, T., Hahn, C., Hayrapetyan, A., Hofmann, J., Kegel, S., Khalid, F., Köseoglu, I., Kripko, A., Kühn, W., Metag, V., Moritz, M., Nanova, M., Novotny, R., Orsich, P., Pereira-de-Lira, J., Sachs, M., Schmidt, M., Schubert, R., Strickert, M., Wasem, T., Zaunick, H. G., Tomasi-Gustafsson, E., Glazier, D., Ireland, D., Seitz, B., Kappert, R., Kavatsyuk, M., Loehner, H., Messchendorp, J., Rodin, V., Kalita, K., Huang, G., Liu, D., Peng, H., Qi, H., Sun, Y., Zhou, X., Kunze, M., Azizi, K., Olgun, A. T., Tavukoglu, Z., Derichs, A., Dosdall, R., Esmail, W., Gillitzer, A., Goldenbaum, F., Grunwald, D., Jokhovets, L., Kannika, J., Kulessa, P., Orfanitski, S., Perez-Andrade, G., Prasuhn, D., Prencipe, E., Pütz, J., Rosenthal, E., Schadmand, S., Schmitz, R., Scholl, A., Sefzick, T., Serdyuk, V., Stockmanns, T., Veretennikov, D., Wintz, P., Wüstner, P., Xu, H., Zhou, Y., Cao, X., Hu, Q., Liang, Y., Rigato, V., Isaksson, L., Achenbach, P., Corell, O., Denig, A., Distler, M., Hoek, M., Lauth, W., Leithoff, H. H., Merkel, H., Müller, U., Petersen, J., Pochodzalla, J., Schlimme, S., Sfienti, C., Thiel, M., Bleser, S., Bölting, M., Capozza, L., Dbeyssi, A., Ehret, A., Klasen, R., Kliemt, R., Maas, F., Motzko, C., Noll, O., Piñeiro, D. Rodríguez, Schupp, F., Steinen, M., Wolff, S., Zimmermann, I., Kazlou, D., Korzhik, M., Missevitch, O., Balanutsa, P., Chernetsky, V., Demekhin, A., Dolgolenko, A., Fedorets, P., Gerasimov, A., Golubev, A., Kantsyrev, A., Kirin, D. Y., Kristi, N., Ladygina, E., Luschevskaya, E., Matveev, V. A., Panjushkin, V., Stavinskiy, A. V., Balashoff, A., Boukharov, A., Bukharova, M., Malyshev, O., Vishnevsky, E., Bonaventura, D., Brand, P., Hetz, B., Hüsken, N., Kellers, J., Khoukaz, A., Klostermann, D., Mannweiler, C., Vestrick, S., Bumrungkoh, D., Herold, C., Khosonthongkee, K., Kobdaj, C., Limphirat, A., Manasatitpong, K., Nasawad, T., Pongampai, S., Simantathammakul, T., Srisawad, P., Wongprachanukul, N., Yan, Y., Yu, C., Zhang, X., Zhu, W., Antokhin, E., Barnyakov, A. Yu., Beloborodov, K., Blinov, V. E., Kuyanov, I. A., Pivovarov, S., Pyata, E., Tikhonov, Y., Blinov, A. E., Kononov, S., Kravchenko, E. A., Lattery, M., Boca, G., Duda, D., Finger, M., Finger, Jr., M., Kveton, A., Prochazka, I., Slunecka, M., Volf, M., Jary, V., Korchak, O., Marcisovsky, M., Neue, G., Novy, J., Tomasek, L., Tomasek, M., Virius, M., Vrba, V., Abramov, V., Bukreeva, S., Chernichenko, S., Derevschikov, A., Ferapontov, V., Goncharenko, Y., Levin, A., Maslova, E., Melnik, Y., Meschanin, A., Minaev, N., Mochalov, V., Moiseev, V., Morozov, D., Nogach, L., Poslavskiy, S., Ryazantsev, A., Ryzhikov, S., Semenov, P., Shein, I., Uzunian, A., Vasiliev, A., Yakutin, A., Belostotski, S., Fedotov, G., Izotov, A., Manaenkov, S., Miklukho, O., Cederwall, B., Preston, M., Tegner, P. E., Wölbing, D., Gandhi, K., Rai, A. K., Godre, S., Crede, V., Dobbs, S., Eugenio, P., Bussa, M. P., Spataro, S., Calvo, D., De Remigis, P., Filippi, A., Mazza, G., Wheadon, R., Iazzi, F., Lavagno, A., Akram, A., Calen, H., Andersson, W. Ikegami, Johansson, T., Kupsc, A., Marciniewski, P., Papenbrock, M., Regina, J., Rieger, J., Schönning, K., Wolke, M., Chlopik, A., Kesik, G., Melnychuk, D., Tarasiuk, J., Wojciechowski, M., Wronka, S., Zwieglinski, B., Amsler, C., Bühler, P., Marton, J., Zimmermann, S., Fischer, C. S., Haidenbauer, J., Hanhart, C., Lutz, M. F. M., and Ryan, Sinéad M.
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High Energy Physics - Experiment ,Nuclear Experiment - Abstract
The Facility for Antiproton and Ion Research (FAIR) in Darmstadt, Germany, provides unique possibilities for a new generation of hadron-, nuclear- and atomic physics experiments. The future antiProton ANnihilations at DArmstadt (PANDA or $\overline{\rm P}$ANDA) experiment at FAIR will offer a broad physics programme, covering different aspects of the strong interaction. Understanding the latter in the non-perturbative regime remains one of the greatest challenges in contemporary physics. The antiproton-nucleon interaction studied with PANDA provides crucial tests in this area. Furthermore, the high-intensity, low-energy domain of PANDA allows for searches for physics beyond the Standard Model, e.g. through high precision symmetry tests. This paper takes into account a staged approach for the detector setup and for the delivered luminosity from the accelerator. The available detector setup at the time of the delivery of the first antiproton beams in the HESR storage ring is referred to as the \textit{Phase One} setup. The physics programme that is achievable during Phase One is outlined in this paper., Comment: 35 pages, 15 figures
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- 2021
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10. Metadata-guided Consistency Learning for High Content Images.
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Johan Fredin Haslum, Christos Matsoukas, Karl-Johan Leuchowius, Erik Müllers, and Kevin Smith 0001
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- 2023
11. Symptomatische Therapie der Multiplen Sklerose
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Becker, J., Hoppe, K., Müllers, M., Pompsch, M., Rogozinski, R., Strunk, D., and Krämer, M.
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- 2023
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12. Measurement of polarization observables TPHπ0η, TPHπ0η, and TPHπ0η in TPHπ0η and TPHπ0η photoproduction off quasi-free nucleons
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Jermann, N., Krusche, B., Metag, V., Afzal, F., Badea, M., Beck, R., Bielefeldt, P., Bieling, J., Biroth, M., Blanke, E., Borisov, N., Bornstein, M., Brinkmann, K.-T., Ciupka, S., Crede, V., Dolzhikov, A., Drexler, P., Dutz, H., Elsner, D., Fedorov, A., Frommberger, F., Gardner, S., Ghosal, D., Goertz, S., Gorodnov, I., Grüner, M., Hammann, C., Hartmann, J., Hillert, W., Hoffmeister, P., Honisch, C., Jude, T. C., Kalischewski, F., Ketzer, B., Klassen, P., Klein, F., Klempt, E., Knaust, J., Kolanus, N., Kreit, J., Krönert, P., Lang, M., Lazarev, A. B., Livingston, K., Lutterer, S., Mahlberg, P., Meier, C., Meyer, W., Mitlasoczki, B., Müllers, J., Nanova, M., Neganov, A., Nikonov, K., Noël, J. F., Ostrick, M., Ottnad, J., Otto, B., Penman, G., Poller, T., Proft, D., Reicherz, G., Reinartz, N., Richter, L., Runkel, S., Salisbury, B., Sarantsev, A. V., Schaab, D., Schmidt, C., Schmieden, H., Schultes, J., Seifen, T., Spieker, K., Stausberg, N., Steinacher, M., Taubert, F., Thiel, A., Thoma, U., Thomas, A., Urban, M., Urff, G., Usov, Y., van Pee, H., Wang, Y. C., Wendel, C., Wiedner, U., and Wunderlich, Y.
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- 2023
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13. Shallow roots of different crops have greater water uptake rates per unit length than deep roots in well-watered soil
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Müllers, Yannik, Postma, Johannes A., Poorter, Hendrik, Kochs, Johannes, Pflugfelder, Daniel, Schurr, Ulrich, and van Dusschoten, Dagmar
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- 2022
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14. Assessing the Effect of Cancer Diagnosis on Beliefs about Comorbid Diabetes
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Muellers, Kimberly A., Harris, Yael T., Wisnivesky, Juan P., and Lin, Jenny J.
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- 2023
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15. New data on $\vec{\gamma} \vec{p}\rightarrow \eta p$ with polarized photons and protons and their implications for $N^* \to N\eta$ decays
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Müller, J., Hartmann, J., Grüner, M., Afzal, F., Anisovich, A. V., Bantes, B., Bayadilov, D., Beck, R., Becker, M., Beloglazov, Y., Berlin, M., Bichow, M., Böse, S., Brinkmann, K. -T., Challand, T., Crede, V., Dietz, F., Dieterle, M., Drexler, P., Dutz, H., Eberhardt, H., Elsner, D., Ewald, R., Fornet-Ponse, K., Friedrich, S., Frommberger, F., Funke, C., Gottschall, M., Gridnev, A., Goertz, S., Gutz, E., Hammann, C., Hannen, V., Hannappel, J., Herick, J., Hillert, W., Hoffmeister, P., Honisch, C., Jahn, O., Jude, T., Jaegle, I., Käser, A., Kaiser, D., Kalinowsky, H., Kalischewski, F., Kammer, S., Keshelashvili, I., Klassen, P., Kleber, V., Klein, F., Klempt, E., Koop, K., Krusche, B., Kube, M., Lang, M., Lopatin, I., Maghrbi, Y., Mahlberg, P., Makonyi, K., Messi, F., Metag, V., Meyer, W., Müllers, J., Nanova, M., Nikonov, V., Novinski, D., Novotny, R., Piontek, D., Reicherz, G., Rosenbaum, C., Rostomyan, T., Roth, B., Sarantsev, A., Schmidt, C., Schmieden, H., Schmitz, R., Seifen, T., Sokhoyan, V., Thiel, A., Thoma, U., Urban, M., van Pee, H., Walther, D., Wendel, C., Wiedner, U., Wilson, A., Winnebeck, A., Witthauer, L., and Collaboration, CBELSA/TAPS
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Nuclear Experiment - Abstract
The polarization observables $T, E, P, H$, and $G$ in photoproduction of $\eta$ mesons off protons are measured for photon energies from threshold to $W=2400\,$MeV ($T$), 2280 MeV ($E$), 1620 MeV ($P, H$), or 1820 MeV ($G$), covering nearly the full solid angle. The data are compared to predictions from the SAID, MAID, J\"uBo, and BnGa partial-wave analyses. A refit within the BnGa approach including further data yields precise branching ratios for the $N\eta$ decay of nucleon resonances. A $N\eta$-branching ratio of $0.33\pm 0.04$ for $N(1650)1/2^-$ is found, which reduces the large and controversially discussed $N\eta$-branching ratio difference of the two lowest mass $J^P=1/2^-$-resonances significantly., Comment: 10 pages, 11 figures
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- 2019
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16. Measurement of the Helicity Asymmetry $E$ for the reaction $ \gamma p\to \pi^0 p$
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collaboration, CBELSA/TAPS, Gottschall, M., Afzal, F., Anisovich, A. V., Bayadilov, D., Beck, R., Bichow, M., Brinkmann, K. -Th., Crede, V., Dieterle, M., Dietz, F., Dutz, H., Eberhardt, H., Elsner, D., Ewald, R., Fornet-Ponse, K., Friedrich, St., Frommberger, F., Gridnev, A., Grüner, M., Gutz, E., Hammann, Ch., Hannappel, J., Hartmann, J., Hillert, W., Hoffmeister, Ph., Honisch, Ch., Jude, T., Kammer, S., Kalinowsky, H., Keshelashvili, I., Klassen, P., Klein, F., Klempt, E., Koop, K., Krusche, B., Kube, M., Lang, M., Lopatin, I., Mahlberg, P., Makonyi, K., Metag, V., Meyer, W., Müller, J., Müllers, J., Nanova, M., Nikonov, V., Novotny, R., Piontek, D., Reicherz, G., Rostomyan, T., Sarantsev, A., Schmidt, Ch., Schmieden, H., Seifen, T., Sokhoyan, V., Spieker, K., Thiel, A., Thoma, U., Urban, M., van Pee, H., Walther, D., Wendel, Ch., Werthmüller, D., Wiedner, U., Wilson, A., Winnebeck, A., Witthauer, L., and Wunderlich, Y.
- Subjects
Nuclear Experiment - Abstract
A measurement of the double-polarization observable $E$ for the reaction $\gamma p\to \pi^0 p$ is reported. The data were taken with the CBELSA/TAPS experiment at the ELSA facility in Bonn using the Bonn frozen-spin butanol (C$_4$H$_9$OH) target, which provided longitudinally-polarized protons. Circularly-polarized photons were produced via bremsstrahlung of longitudinally-polarized electrons. The data cover the photon energy range from $E_\gamma =600$~MeV to $E_\gamma =2310$~MeV and nearly the complete angular range. The results are compared to and have been included in recent partial wave analyses., Comment: 21 pages
- Published
- 2019
17. Enhanced dissolution rate of nimodipine through β-lactoglobulin based formulation
- Author
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Leng, Donglei, Bulduk, Bulut, Anlahr, Johanna, Müllers, Wouter, and Löbmann, Korbinian
- Published
- 2023
- Full Text
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18. The {\eta}'-carbon potential at low meson momenta
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Nanova, M., Friedrich, S., Metag, V., Paryev, E. Ya., Afzal, F. N., Bayadilov, D., Bantes, B., Beck, R., Becker, M., Böse, S., Brinkmann, K. -T., Crede, V., Drexler, P., Eberhardt, H., Elsner, D., Frommberger, F., Funke, Ch., Gottschall, M., Grüner, M., Gutz, E., Hammann, Ch., Hannappel, J., Hartmann, J., Hillert, W., Hoffmeister, Ph., Honisch, Ch., Jude, T., Kaiser, D., Kalischewski, F., Keshelashvili, I., Klein, F., Koop, K., Krusche, B., Lang, M., Makonyi, K., Messi, F., Müller, J., Müllers, J., Piontek, D., Rostomyan, T., Schaab, D., Schmidt, Ch., Schmieden, H., Schmitz, R., Seifen, T., Sokhoyan, V., Sowa, C., Spieker, K., Thiel, A., Thoma, U., Triffterer, T., Urban, M., van Pee, H., Walther, D., Wendel, Ch., Werthmüller, D., Wiedner, U., Wilson, A., Witthauer, L., Wunderlich, Y., and Zaunick, H. -G.
- Subjects
Nuclear Experiment - Abstract
The production of $\eta^\prime$ mesons in coincidence with forward-going protons has been studied in photon-induced reactions on $^{12}$C and on a liquid hydrogen (LH$_2$) target for incoming photon energies of 1.3-2.6 GeV at the electron accelerator ELSA. The $\eta^\prime$ mesons have been identified via the $\eta^\prime\rightarrow \pi^0 \pi^0\eta \rightarrow 6 \gamma$ decay registered with the CBELSA/TAPS detector system. Coincident protons have been identified in the MiniTAPS BaF$_2$ array at polar angles of $2^{\circ} \le \theta _{p} \le 11^{\circ}$. Under these kinematic constraints the $\eta^\prime$ mesons are produced with relatively low kinetic energy ($\approx$ 150 MeV) since the coincident protons take over most of the momentum of the incident-photon beam. For the C-target this allows the determination of the real part of the $\eta^\prime$-carbon potential at low meson momenta by comparing with collision model calculations of the $\eta^\prime$ kinetic energy distribution and excitation function. Fitting the latter data for $\eta^\prime$ mesons going backwards in the center-of-mass system yields a potential depth of V = $-$(44 $\pm$ 16(stat)$\pm$15(syst)) MeV, consistent with earlier determinations of the potential depth in inclusive measurements for average $\eta^\prime$ momenta of $\approx$ 1.1 GeV/$c$. Within the experimental uncertainties, there is no indication of a momentum dependence of the $\eta^\prime$-carbon potential. The LH$_2$ data, taken as a reference to check the data analysis and the model calculations, provide differential and integral cross sections in good agreement with previous results for $\eta^\prime$ photoproduction off the free proton., Comment: 9 pages, 13 figures. arXiv admin note: text overlap with arXiv:1608.06074
- Published
- 2018
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19. Coherent perfect absorption of nonlinear matter waves
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Müllers, Andreas, Santra, Bodhaditya, Baals, Christian, Jiang, Jian, Benary, Jens, Labouvie, Ralf, Zezyulin, Dmitry A., Konotop, Vladimir V., and Ott, Herwig
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Condensed Matter - Quantum Gases ,Nonlinear Sciences - Pattern Formation and Solitons - Abstract
Coherent perfect absorption is the complete extinction of incoming radiation by a complex potential in a physical system supporting wave propagation. The concept was proven for linear waves in variety of systems including light interacting with absorbing scatterers, plasmonic metasurfaces and graphene films, as well as sound waves. We extend the paradigm to coherent perfect absorption of nonlinear waves and experimentally demonstrate it for matter waves in an atomic Bose-Einstein condensate. Coherent absorption of nonlinear matter waves is achieved easier than its linear analogs because the strength of two-body interactions offers additional freedom for control. Implementation of the coherent perfect absorber of Bose-Einstein condensates paves the way towards broad exploitation of the phenomenon in nonlinear optics, exciton-polariton condensates, acoustics, and other areas of nonlinear physics. It also opens perspectives for designing atomic laser.
- Published
- 2018
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20. Hairy surfaces by cold drawing leading to dense lawns of high aspect ratio hairs
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Stefan Müllers, Mara Florea-Hüring, Bernhard von Vacano, Bernd Bruchmann, and Jürgen Rühe
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Medicine ,Science - Abstract
Abstract The surfaces of many organisms are covered with hairs, which are essential for their survival in a complex environment. The generation of artificial hairy surfaces from polymer materials has proven to be challenging as it requires the generation of structures with very high aspect ratios (AR). We report on a technique for the fabrication of surfaces covered with dense layers of very high AR nanoscale polymer hairs. To this, templates having pores with diameters of several hundred nanometers are filled with a polymer melt by capillary action. The polymer is then allowed to cool and the template is mechanically removed. Depending on the conditions employed, the formed structures can be a simple replica of the pore, or the polymer is deformed very strongly by cold drawing to yield in long hairs, with hair densities significantly up to 6,6 × 108 hairs/cm2 at AR of much higher than 200. The mechanism of hair formation is attributed to a delicate balance between the adhesion forces of the polymer in the pore and the yield force acting on it during mechanically demolding. We demonstrate how with very little effort and within a timescale of seconds unique topographies can be obtained, which can dramatically tailor the wetting properties of common polymers.
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- 2022
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21. GRK2 selectively attenuates the neutrophil NADPH-oxidase response triggered by β-arrestin recruiting GPR84 agonists
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Fredriksson, Johanna, Holdfeldt, André, Mårtensson, Jonas, Björkman, Lena, Møller, Thor C., Müllers, Erik, Dahlgren, Claes, Sundqvist, Martina, and Forsman, Huamei
- Published
- 2022
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22. Hairy surfaces by cold drawing leading to dense lawns of high aspect ratio hairs
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Müllers, Stefan, Florea-Hüring, Mara, von Vacano, Bernhard, Bruchmann, Bernd, and Rühe, Jürgen
- Published
- 2022
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23. A high repetition deterministic single ion source
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Sahin, Cihan, Geppert, Philipp, Müllers, Andreas, and Ott, Herwig
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Physics - Atomic Physics - Abstract
We report on a deterministic single ion source with high repetition rate and high fidelity. The source employs a magneto-optical trap, where ultracold Rubidium atoms are photoionized. The electrons herald the creation of a corresponding ion, whose timing information is used to manipulate its trajectory in flight. We demonstrate an ion rate of up to 40 kHz and achieve a fidelity for single ion operation of 98 %. The technique can be used for all atomic species, which can be laser-cooled, and opens up new applications in ion microscopy, ion implantation and surface spectroscopy.
- Published
- 2017
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24. Photoproduction of eta mesons from the neutron: cross sections and double polarization observable E
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Witthauer, L., Dieterle, M., Afzal, F., Anisovich, A. V., Bantes, B., Bayadilov, D., Beck, R., Bichow, M., Brinkmann, K. -T., Böse, S., Challand, Th., Crede, V., Dutz, H., Eberhardt, H., Elsner, D., Ewald, R., Fornet-Ponse, K., Friedrich, St., Frommberger, F., Funke, Ch., Goertz, St., Gottschall, M., Gridnev, A., Grüner, M., Gutzınst, E., Hammann, D., Hammann, Ch., Hannappel, J., Hartmann, J., Hillert, W., Hoffmeister, Ph., Honisch, Ch., Jude, T., Kaiser, D., Kalinowsky, H., Kalischewski, F., Kammer, S., Käser, A., Keshelashvili, I., Klassen, P., Kleber, V., Klein, F., Koop, K., Krusche, B., Lang, M., Lopatin, I., Mahlberg, Ph., Makonyi, K., Metag, V., Meyer, W., Müller, J., Müllers, J., Nanova, M., Nikonov, V., Piontek, D., Reicherz, G., Rostomyan, T., Sarantsev, A., Schmidt, Ch., Schmieden, H., Seifen, T., Sokhoyan, V., Spieker, K., Thiel, A., Thoma, U., Urban, M., van Pee, H., Walford, N. K., Walther, D., Wendel, Ch., Werthmüller, D., Wilson, A., and Winnebeck, A.
- Subjects
Nuclear Experiment - Abstract
Photoproduction of $\eta$ mesons from neutrons} \abstract{Results from measurements of the photoproduction of $\eta$ mesons from quasifree protons and neutrons are summarized. The experiments were performed with the CBELSA/TAPS detector at the electron accelerator ELSA in Bonn using the $\eta\to3\pi^{0}\to6\gamma$ decay. A liquid deuterium target was used for the measurement of total cross sections and angular distributions. The results confirm earlier measurements from Bonn and the MAMI facility in Mainz about the existence of a narrow structure in the excitation function of $\gamma n\rightarrow n\eta$. The current angular distributions show a forward-backward asymmetry, which was previously not seen, but was predicted by model calculations including an additional narrow $P_{11}$ state. Furthermore, data obtained with a longitudinally polarized, deuterated butanol target and a circularly polarized photon beam were analyzed to determine the double polarization observable $E$. Both data sets together were also used to extract the helicity dependent cross sections $\sigma_{1/2}$ and $\sigma_{3/2}$. The narrow structure in the excitation function of $\gamma n\rightarrow n\eta$ appears associated with the helicity-1/2 component of the reaction.
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- 2017
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25. Acrylate‐derived RAFT Polymers for Enzyme Hyperactivation – Boosting the α‐Chymotrypsin Enzyme Activity Using Tailor‐Made Poly(2‐Carboxyethyl)acrylate (PCEA)
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Müllers, Yannic, primary, Sadr, Ahmad Shahir, additional, Schenderlein, Matthias, additional, Pallab, Nazim, additional, Davari, Mehdi D., additional, Glebe, Ulrich, additional, and Reifarth, Martin, additional
- Published
- 2024
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26. Momentum dependence of the imaginary part of the $\omega$- and $\eta^\prime$-nucleus optical potential
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Friedrich, S., Nanova, M., Metag, V., Afzal, F. N., Bayadilov, D., Bantes, B., Beck, R., Becker, M., Böse, S., Brinkmann, K. -T., Crede, V., Drexler, P., Eberhardt, H., Elsner, D., Frommberger, F., Funke, Ch., Gottschall, M., Grüner, M., Gutz, E., Hammann, Ch., Hannappel, J., Hartmann, J., Hillert, W., Hoffmeister, Ph., Honisch, Ch., Jude, T., Kaiser, D., Kalischewski, F., Keshelashvili, I., Klein, F., Koop, K., Krusche, B., Lang, M., Makonyi, K., Messi, F., Müller, J., Müllers, J., Piontek, D. -M., Rostomyan, T., Schaab, D., Schmidt, Ch., Schmieden, H., Schmitz, R., Seifen, T., Sokhoyan, V., Sowa, C., Spieker, K., Thiel, A., Thoma, U., Triffterer, T., Urban, M., van Pee, H., Walther, D., Wendel, Ch., Werthmüller, D., Wiedner, U., Wilson, A., Witthauer, L., Wunderlich, Y., and Zaunick, H. -G.
- Subjects
Nuclear Experiment - Abstract
The photoproduction of $\omega$ and $\eta^\prime$ mesons off carbon and niobium nuclei has been measured as a function of the meson momentum for incident photon energies of 1.2-2.9 GeV at the electron accelerator ELSA. The mesons have been identified via the $\omega \rightarrow \pi^0 \gamma \rightarrow 3 \gamma$ and $\eta^\prime\rightarrow \pi^0 \pi^0\eta \rightarrow 6 \gamma$ decays, respectively, registered with the CBELSA/TAPS detector system. From the measured meson momentum distributions the momentum dependence of the transparency ratio has been determined for both mesons. Within a Glauber analysis the in-medium $\omega$ and $\eta^\prime$ widths and the corresponding absorption cross sections have been deduced as a function of the meson momentum. The results are compared to recent theoretical predictions for the in-medium $\omega$ width and $\eta^\prime$-N absorption cross sections. The energy dependence of the imaginary part of the $\omega$- and $\eta^\prime$-nucleus optical potential has been extracted. The finer binning of the present data compared to the existing data allows a more reliable extrapolation towards the production threshold. The modulus of the imaginary part of the $\eta^\prime$ nucleus potential is found to be about three times smaller than recently determined values of the real part of the $\eta^\prime$-nucleus potential, which makes the $\eta^\prime$ meson a suitable candidate for the search for meson-nucleus bound states. For the $\omega$ meson, the modulus of the imaginary part near threshold is comparable to the modulus of the real part of the potential. As a consequence, only broad structures can be expected which makes the observation of $\omega$ mesic states very difficult experimentally., Comment: 10 pages, 8 figures
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- 2016
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27. 'What's (the) Matter?', A Show on Elementary Particle Physics with 28 Demonstration Experiments
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Dreiner, Herbi K., Becker, Max, Borzyszkowski, Mikolaj, Braun, Maxim, Faßbender, Alexander, Hampel, Julia, Hansen, Maike, Hebecker, Dustin, Heepenstrick, Timo, Heinz, Sascha, Hortmanns, Katharina, Jost, Christian, Kortmann, Michael, Kruckow, Matthias U., Leuteritz, Till, Lütz, Claudia, Mahlberg, Philip, Müllers, Johannes, Opferkuch, Toby, Paul, Ewald, Pauli, Peter, Rossbach, Merlin, Schaepe, Steffen, Schiffer, Tobias, Schmidt, Jan F., Schüller-Ruhl, Jana, Schürmann, Christoph, Ubaldi, Lorenzo, and Wagner-Carena, Sebastian
- Subjects
Physics - Popular Physics ,High Energy Physics - Experiment ,High Energy Physics - Phenomenology ,High Energy Physics - Theory ,Physics - Physics Education - Abstract
We present the screenplay of a physics show on particle physics, by the Physikshow of Bonn University. The show is addressed at non-physicists aged 14+ and communicates basic concepts of elementary particle physics including the discovery of the Higgs boson in an entertaining fashion. It is also demonstrates a successful outreach activity heavily relying on the university physics students. This paper is addressed at anybody interested in particle physics and/or show physics. This paper is also addressed at fellow physicists working in outreach, maybe the experiments and our choice of simple explanations will be helpful. Furthermore, we are very interested in related activities elsewhere, in particular also demonstration experiments relevant to particle physics, as often little of this work is published. Our show involves 28 live demonstration experiments. These are presented in an extensive appendix, including photos and technical details. The show is set up as a quest, where 2 students from Bonn with the aid of a caretaker travel back in time to understand the fundamental nature of matter. They visit Rutherford and Geiger in Manchester around 1911, who recount their famous experiment on the nucleus and show how particle detectors work. They travel forward in time to meet Lawrence at Berkeley around 1950, teaching them about the how and why of accelerators. Next, they visit Wu at DESY, Hamburg, around 1980, who explains the strong force. They end up in the LHC tunnel at CERN, Geneva, Switzerland in 2012. Two experimentalists tell them about colliders and our heroes watch live as the Higgs boson is produced and decays. The show was presented in English at Oxford University and University College London, as well as Padua University and ICTP Trieste. It was 1st performed in German at the Deutsche Museum, Bonn (5/'14). The show has eleven speaking parts and involves in total 20 people., Comment: 113 pages, 88 figures. An up to date version of the paper with high resolution pictures can be found at http://www.th.physik.uni-bonn.de/People/dreiner/Downloads/. In v2 the acknowledgements and a citation are corrected
- Published
- 2016
28. Determination of the real part of the {\eta}'-Nb optical potential
- Author
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Nanova, M., Friedrich, S., Metag, V., Paryev, E. Ya., Afzal, F. N., Bayadilov, D., Beck, R., Becker, M., Böse, S., Brinkmann, K. -T., Crede, V., Elsner, D., Frommberger, F., Grtuner, M., Gutz, E., Hammann, Ch., Hannappel, J., Hartmann, J., Hillert, W., Hoffmeister, P., Honisch, Ch., Jude, T., Kalischewski, F., Keshelashvili, I., Klein, F., Koop, K., Krusche, B., Lang, M., Makonyi, K., Messi, F., Müller, J., Müllers, J., Piontek, D. M., Rostomyan, T., Schaab, D., Schmidt, C., Schmieden, H., Schmitz, R., Seifen, T., Sowa, C., Spieker, K., Thiel, A., Thoma, U., Tristerer, T., Urban, M., van Pee, H., Walther, D., Wendel, C., Werthmüller, D., Wiedner, U., Wilson, A., Witthauer, L., Wunderlich, Y., and Zaunick, H. -G.
- Subjects
Nuclear Experiment - Abstract
The excitation function and momentum distribution of {\eta}' mesons have been measured in photoproduction off 93^Nb in the energy range of 1.2-2.9 GeV. The experiment has been performed with the combined Crystal Barrel and MiniTAPS detector system, using tagged photon beams from the ELSA electron accelerator. Information on the sign and magnitude of the real part of the {\eta}'-Nb potential has been extracted from a comparison of the data with model calculations. An attractive potential of -(41 \pm 10(stat) \pm 15(syst)) MeV depth at normal nuclear matter density is deduced within model uncertainties. This value is consistent with the potential depth of -(37 \pm 10(stat) \pm 10(syst)) MeV obtained in an earlier measurement for a light nucleus (carbon). This relatively shallow {\eta}'-nucleus potential will make the search for {\eta}'-nucleus bound states more difficult., Comment: 9 pages, 6 figures
- Published
- 2016
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29. Double-polarization observable G in neutral-pion photoproduction off the proton
- Author
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Thiel, A., Eberhardt, H., Lang, M., Afzal, F., Anisovich, A. V., Bantes, B., Bayadilov, D., Beck, R., Bichow, M., Brinkmann, K. -T., Böse, S., Crede, V., Dieterle, M., Dutz, H., Elsner, D., Ewald, R., Fornet-Ponse, K., Friedrich, St., Frommberger, F., Funke, Ch., Goertz, St., Gottschall, M., Gridnev, A., Grüner, M., Gutz, E., Hammann, D., Hammann, Ch., Hannappel, J., Hartmann, J., Hillert, W., Hoffmeister, Ph., Honisch, Ch., Jude, T., Kaiser, D., Kalinowsky, H., Kalischewski, F., Kammer, S., Keshelashvili, I., Klassen, P., Kleber, V., Klein, F., Klempt, E., Koop, K., Krusche, B., Kube, M., Lopatin, I., Mahlberg, Ph., Makonyi, K., Metag, V., Meyer, W., Müller, J., Müllers, J., Nanova, M., Nikonov, V., Piontek, D., Reeve, S., Reicherz, G., Runkel, S., Sarantsev, A., Schmidt, Ch., Schmieden, H., Seifen, T., Sokhoyan, V., Spieker, K., Thoma, U., Urban, M., van Pee, H., Walther, D., Wendel, Ch., Wilson, A., Winnebeck, A., and Witthauer, L.
- Subjects
Nuclear Experiment - Abstract
This paper reports on a measurement of the double-polarization observable G in $\pi^0$ photoproduction off the proton using the CBELSA/TAPS experiment at the ELSA accelerator in Bonn. The observable G is determined from reactions of linearly-polarized photons with longitudinally-polarized protons. The polarized photons are produced by bremsstrahlung off a properly oriented diamond radiator. A frozen spin butanol target provides the polarized protons. The data cover the photon energy range from 617 to 1325 MeV and a wide angular range. The experimental results for G are compared to predictions by the Bonn-Gatchina (BnGa), J\"ulich-Bonn (J\"uBo), MAID and SAID partial wave analyses. Implications of the new data for the pion photoproduction multipoles are discussed.
- Published
- 2016
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30. A structural equation model of relationships of health literacy, illness and medication beliefs with medication adherence among patients with chronic obstructive pulmonary disease
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Agarwal, Parul, Lin, Jenny, Muellers, Kimberly, O’Conor, Rachel, Wolf, Michael, Federman, Alex D., and Wisnivesky, Juan P.
- Published
- 2021
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31. Identifying Behavioral Phenotypes in Chronic Illness: Self-Management of COPD and Comorbid Hypertension
- Author
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Perez-Benzo, Grace M., Muellers, Kimberly, Chen, Shiqi, Liu, Bian, Bagiella, Emilia, O'Conor, Rachel, Wolf, Michael S., Wisnivesky, Juan P., and Federman, Alex D.
- Published
- 2021
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32. Normoglycemia and physiological cortisone level maintain glucose homeostasis in a pancreas-liver microphysiological system.
- Author
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Rigal, Sophie, Casas, Belén, Kanebratt, Kajsa P., Wennberg Huldt, Charlotte, Magnusson, Lisa U., Müllers, Erik, Karlsson, Fredrik, Clausen, Maryam, Hansson, Sara F., Leonard, Louise, Cairns, Jonathan, Jansson Löfmark, Rasmus, Ämmälä, Carina, Marx, Uwe, Gennemark, Peter, Cedersund, Gunnar, Andersson, Tommy B., and Vilén, Liisa K.
- Abstract
Current research on metabolic disorders and diabetes relies on animal models because multi-organ diseases cannot be well studied with standard in vitro assays. Here, we have connected cell models of key metabolic organs, the pancreas and liver, on a microfluidic chip to enable diabetes research in a human-based in vitro system. Aided by mechanistic mathematical modeling, we demonstrate that hyperglycemia and high cortisone concentration induce glucose dysregulation in the pancreas-liver microphysiological system (MPS), mimicking a diabetic phenotype seen in patients with glucocorticoid-induced diabetes. In this diseased condition, the pancreas-liver MPS displays beta-cell dysfunction, steatosis, elevated ketone-body secretion, increased glycogen storage, and upregulated gluconeogenic gene expression. Conversely, a physiological culture condition maintains glucose tolerance and beta-cell function. This method was reproducible in two laboratories and was effective in multiple pancreatic islet donors. The model also provides a platform to identify new therapeutic proteins, as demonstrated with a combined transcriptome and proteome analysis.A human-cell-based pancreas-liver microphysiological system serves as a preclinical platform for studying glucose–insulin homeostasis and disease mechanisms of glucose dysregulation, offering a tool for identifying targets and testing drugs. [ABSTRACT FROM AUTHOR]
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- 2024
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33. Ultra-Short-Pulse Laser Filaments for Float Glass Cutting: Influence of Laser Parameters on Micro Cracks Formation
- Author
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Ferdinand Werr, Urs Eppelt, Ludger Müllers, and Dominique de Ligny
- Subjects
laser cutting ,micro machining ,float glass ,filament cleaving ,surface analysis ,stress optic ,Physics ,QC1-999 - Abstract
Utilizing ultra-short-pulse laser filamentation of glass is one of the latest developed techniques to cut glass. In comparison with other techniques the superior benefits are a small heat-affected zone, a quasi-non-gap cut, and the possibility to free from cut. However, despite the large interest in the laser/glass interaction for various laser sources and pulse durations, the process of cleaving and the underlying mechanisms are fairly undescribed. In this study, we utilized a Nd:YAG laser with an average power of 100 W, a center wavelength of 1,064 nm, and a pulse duration of 12 ps via a specially designed optic to generate laser filamentation in soda-lime- and borosilicate glass with varying Pitch and Burst parameters. The filaments and cut edge are analyzed with scanning electron- and laser scanning microscopy to study the topological phenomena and roughness. Photoelastic measurements were done to assess the stress distribution within the glass and show cumulative interactions at the filament extremity. From the observations made, phenomenological models are proposed to describe the initial micro crack formation considering the shock wave and thermal influence caused by the laser pulses. Two types of micro cracks are identified, with radial cracks passing through the filament and bypass cracks that form around the laser-affected zone. Models are elaborated for both glass types to evaluate the influence of a parameter change on the micro crack formation and the cleaving guidance. The different behavior between soda-lime- and borosilicate glass, with their distinct physical properties, helps to interpret the influence of laser parameters on the micro crack formation and the cleaving guidance.
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- 2022
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34. A high-content, in vitro cardiac fibrosis assay for high-throughput, phenotypic identification of compounds with anti-fibrotic activity
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Palano, G., Jansson, M., Backmark, A., Martinsson, S., Sabirsh, A., Hultenby, K., Åkerblad, P., Granberg, K.L., Jennbacken, K., Müllers, E., and Hansson, E.M.
- Published
- 2020
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35. Concordance of patients’ beliefs about chronic obstructive pulmonary disease, their comorbidities, and their medications
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McInerney, Grace E., Muellers, Kimberly, O'Conor, Rachel, Wolf, Michael S., Leventhal, Howard, Wisnivesky, Juan P., and Federman, Alex D.
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- 2020
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36. Reuse of cast-in-place concrete slabs in new structures
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Felber, Lukas, primary, Dietz, Matthias, additional, Müllers, Ingo, additional, and Nöldgen, Markus, additional
- Published
- 2024
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37. Discovery of retinoic acid receptor agonists as proliferators of cardiac progenitor cells through a phenotypic screening approach
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Lauren Drowley, Jane McPheat, Anneli Nordqvist, Samantha Peel, Ulla Karlsson, Sofia Martinsson, Erik Müllers, Anita Dellsén, Sinead Knight, Ian Barrett, José Sánchez, Björn Magnusson, Boris Greber, Qing‐Dong Wang, and Alleyn T. Plowright
- Subjects
cell proliferation ,gene expression ,high throughput screening assays ,induced pluripotent stem cells ,nuclear receptors ,small molecule libraries ,Medicine (General) ,R5-920 ,Cytology ,QH573-671 - Abstract
Abstract Identification of small molecules with the potential to selectively proliferate cardiac progenitor cells (CPCs) will aid our understanding of the signaling pathways and mechanisms involved and could ultimately provide tools for regenerative therapies for the treatment of post‐MI cardiac dysfunction. We have used an in vitro human induced pluripotent stem cell‐derived CPC model to screen a 10,000‐compound library containing molecules representing different target classes and compounds reported to modulate the phenotype of stem or primary cells. The primary readout of this phenotypic screen was proliferation as measured by nuclear count. We identified retinoic acid receptor (RAR) agonists as potent proliferators of CPCs. The CPCs retained their progenitor phenotype following proliferation and the identified RAR agonists did not proliferate human cardiac fibroblasts, the major cell type in the heart. In addition, the RAR agonists were able to proliferate an independent source of CPCs, HuES6. The RAR agonists had a time‐of‐differentiation‐dependent effect on the HuES6‐derived CPCs. At 4 days of differentiation, treatment with retinoic acid induced differentiation of the CPCs to atrial cells. However, after 5 days of differentiation treatment with RAR agonists led to an inhibition of terminal differentiation to cardiomyocytes and enhanced the proliferation of the cells. RAR agonists, at least transiently, enhance the proliferation of human CPCs, at the expense of terminal cardiac differentiation. How this mechanism translates in vivo to activate endogenous CPCs and whether enhancing proliferation of these rare progenitor cells is sufficient to enhance cardiac repair remains to be investigated.
- Published
- 2020
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38. Evaluating an Accelerometer-Based System for Spine Shape Monitoring.
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Katharina Stollenwerk, Johannes Müllers, Jonas Müller, André Hinkenjann, and Björn Krüger
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- 2018
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39. Evaluating an Accelerometer-Based System for Spine Shape Monitoring
- Author
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Stollenwerk, Katharina, Müllers, Johannes, Müller, Jonas, Hinkenjann, André, Krüger, Björn, Hutchison, David, Series Editor, Kanade, Takeo, Series Editor, Kittler, Josef, Series Editor, Kleinberg, Jon M., Series Editor, Mattern, Friedemann, Series Editor, Mitchell, John C., Series Editor, Naor, Moni, Series Editor, Pandu Rangan, C., Series Editor, Steffen, Bernhard, Series Editor, Terzopoulos, Demetri, Series Editor, Tygar, Doug, Series Editor, Weikum, Gerhard, Series Editor, Gervasi, Osvaldo, editor, Murgante, Beniamino, editor, Misra, Sanjay, editor, Stankova, Elena, editor, Torre, Carmelo M., editor, Rocha, Ana Maria A.C., editor, Taniar, David, editor, Apduhan, Bernady O., editor, Tarantino, Eufemia, editor, and Ryu, Yeonseung, editor
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- 2018
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40. Effects of health literacy and cognitive abilities on COPD self-management behaviors: A prospective cohort study
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O'Conor, Rachel, Muellers, Kimberly, Arvanitis, Marina, Vicencio, Daniel P., Wolf, Michael S., Wisnivesky, Juan P., and Federman, Alex D.
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- 2019
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41. Trapped Antihydrogen in Its Ground State
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Gabrielse, G., Kalra, R., Kolthammer, W. S., McConnell, R., Richerme, P., Grzonka, D., Oelert, W., Sefzick, T., Zielinski, M., Fitzakerley, D. W., George, M. C., Hessels, E. A., Storry, C. H., Weel, M., Müllers, A., and Walz, J.
- Subjects
Physics - Atomic Physics - Abstract
Antihydrogen atoms are confined in an Ioffe trap for 15 to 1000 seconds -- long enough to ensure that they reach their ground state. Though reproducibility challenges remain in making large numbers of cold antiprotons and positrons interact, 5 +/- 1 simultaneously-confined ground state atoms are produced and observed on average, substantially more than previously reported. Increases in the number of simultaneously trapped antithydrogen atoms are critical if laser-cooling of trapped antihydrogen is to be demonstrated, and spectroscopic studies at interesting levels of precision are to be carried out.
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- 2012
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42. In vitro Assays and Imaging Methods for Drug Discovery for Cardiac Fibrosis
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Giorgia Palano, Ariana Foinquinos, and Erik Müllers
- Subjects
cardiac fibrosis ,in vitro assays ,3D models ,co-culture systems ,high-content imaging ,drug discovery ,Physiology ,QP1-981 - Abstract
As a result of stress, injury, or aging, cardiac fibrosis is characterized by excessive deposition of extracellular matrix (ECM) components resulting in pathological remodeling, tissue stiffening, ventricular dilatation, and cardiac dysfunction that contribute to heart failure (HF) and eventually death. Currently, there are no effective therapies specifically targeting cardiac fibrosis, partially due to limited understanding of the pathological mechanisms and the lack of predictive in vitro models for high-throughput screening of antifibrotic compounds. The use of more relevant cell models, three-dimensional (3D) models, and coculture systems, together with high-content imaging (HCI) and machine learning (ML)-based image analysis, is expected to improve predictivity and throughput of in vitro models for cardiac fibrosis. In this review, we present an overview of available in vitro assays for cardiac fibrosis. We highlight the potential of more physiological 3D cardiac organoids and coculture systems and discuss HCI and automated artificial intelligence (AI)-based image analysis as key methods able to capture the complexity of cardiac fibrosis in vitro. As 3D and coculture models will soon be sufficiently mature for application in large-scale preclinical drug discovery, we expect the combination of more relevant models and high-content analysis to greatly increase translation from in vitro to in vivo models and facilitate the discovery of novel targets and drugs against cardiac fibrosis.
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- 2021
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43. Continuous Lyman-alpha generation by four-wave mixing in mercury for laser-cooling of antihydrogen
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Kolbe, D., Beczkowiak, A., Diehl, T., Koglbauer, A., Müllers, A., Scheid, M., Stappel, M., Steinborn, R., and Walz, J.
- Subjects
Physics - Optics ,Physics - Atomic Physics - Abstract
Cooling antihydrogen atoms is important for future experiments both to test the fundamental CPT symmetry by high-resolution laser spectroscopy and also to measure the gravitational acceleration of antimatter. Laser-cooling of antihydrogen can be done on the strong 1S-2P transition at the wavelength of Lyman-alpha (121.6nm). A continuous-wave laser at the Lyman-alpha wavelength based on solid-state fundamental lasers is described. By using a two-photon and a near one photon resonance a scan across the whole phasematching curve of the four-wave mixing process is possible. Furthermore the influence of the beam profile of one fundamental beam on the four-wave mixing process is studied., Comment: 4 pages, 4 figures
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- 2010
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44. Spectroscopic characterization of europium binding to a calmodulin-EF4 hand peptide–polymer conjugate.
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Marlina, Dini, Müllers, Yannic, Glebe, Ulrich, and Kumke, Michael U.
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- 2024
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45. Acrylate-derived RAFT polymers for enzyme hyperactivation – Boosting the α-chymotrypsin enzyme activity using tailor-made poly(2-carboxyethyl)acrylate (PCEA)
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Müllers, Yannic, primary, Sadr, Ahmad Shahir, additional, Schenderlein, Matthias, additional, Pallab, Nazim, additional, D. Davari, Mehdi, additional, Glebe, Ulrich, additional, and Reifarth, Martin, additional
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- 2023
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46. Multiple Pregnancy
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Müllers, Sieglinde M., primary, McAuliffe, Fionnuala, additional, and Malone, Fergal D., additional
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- 2020
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47. List of Contributors
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Acharya, Ganesh, primary, Aertsen, Michael, additional, Afshar, Yalda, additional, Ananth, Cande V., additional, Ashworth, Michael, additional, Au, Patrick, additional, Bakalis, Spyros, additional, Benoist, Guillaume, additional, Bilancia, Colleen G., additional, Bilardo, Caterina M., additional, Bryant, Louise D., additional, Butler, Colin R., additional, Van Calenbergh, Frank, additional, Caritis, Steve N., additional, Chitty, Lyn S., additional, Collins, Patricia, additional, Cook, James, additional, Cuckle, Howard, additional, David, Anna L., additional, De Catte, Luc, additional, De Coppi, Paolo, additional, de Jong-Pleij, Elisabeth, additional, De Keersmaecker, Bart, additional, Deprest, Jan, additional, Devlieger, Roland, additional, de Wert, Guido M., additional, Dickinson, Jan E., additional, Dilworth, Mark, additional, Dondorp, Wybo J., additional, Dunk, Caroline E., additional, Everett, Thomas R., additional, Fisher, Jane, additional, Galan, Henry L., additional, Ganapathi, Mythily, additional, Gardiner, Helena M., additional, Gotherstrom, Cecilia, additional, Harding, Richard, additional, Hewison, Jenny, additional, Hewitt, Richard J., additional, Hiersch, Liran, additional, Hill, Melissa, additional, Hillman, Sara L., additional, Hindryckx, An, additional, Hooper, Stuart B., additional, Huppertz, Berthold, additional, Hutchinson, J. Ciaran, additional, Hyett, Jon, additional, Joyeux, Luc, additional, Jurkovic, Davor, additional, Kingdom, John C., additional, Langlois, Sylvie, additional, Lemon, Lara S., additional, Leruez-Ville, Marianne, additional, Lewi, Liesbeth, additional, Levy, Brynn, additional, Loke, Y.W., additional, Lopriore, Enrico, additional, Macones, George A., additional, Malone, Fergal D., additional, Martirosian, Anahit, additional, McAuliffe, Fionnuala, additional, McDougall, Annie R.A., additional, Moise, Kenneth J., additional, Moffett, Ashley, additional, Müllers, Sieglinde M., additional, Neiger, Ran, additional, Newnham, John P., additional, Obican, Sarah G., additional, Odibo, Anthony O., additional, Oepkes, Dick, additional, Pandya, Pranav P., additional, Platt, Lawrence D., additional, Pratt, Rosalind, additional, Rajah, Kuhan, additional, Rao, Rashmi, additional, Richter, Jute, additional, Rosenbloom, Joshua I., additional, Russo, Francesca Maria, additional, Scialli, Anthony R., additional, Sebire, Neil J., additional, Sharkey, Andrew, additional, Shelmerdine, Susan C., additional, Sibley, Colin, additional, Snowise, Saul, additional, Steggerda, Sylke, additional, Su, Emily J., additional, Tang, Mary, additional, Te Pas, Arjan B., additional, Tita, Alan T., additional, Ushakov, Fred, additional, Van den Veyver, Ignatia B., additional, van Klink, Jeanine M., additional, Venkataramanan, Raman, additional, Ville, Yves, additional, Walkiewicz, Magdalena, additional, Wallis, Colin, additional, Walther-Jallow, Lilian, additional, Wapner, Ronald J., additional, Westgren, Magnus, additional, White, Scott W., additional, Wilson, Louise C., additional, Wilson, R. Douglas, additional, Winkelhorst, Dian, additional, Winyard, Paul J.D., additional, Wohlmuth, Christoph, additional, Wou, Karen, additional, Yaron, Yuval, additional, Leung, Kwok Yin, additional, and Yulia, Angela, additional
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- 2020
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48. The potential of ΛΞ- and ΛΞ- studies with PANDA at FAIR
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Barucca, G., Davì, F., Lancioni, G., Mengucci, P., Montalto, L., Natali, P. P., Paone, N., Rinaldi, D., Scalise, L., Erni, W., Krusche, B., Steinacher, M., Walford, N., Cao, N., Liu, Z., Liu, C., Liu, B., Shen, X., Sun, S., Tao, J., Xiong, X. A., Zhao, G., Zhao, J., Albrecht, M., Alkakhi, W., Bökelmann, S., Feldbauer, F., Fink, M., Frech, J., Freudenreich, V., Fritsch, M., Hagdorn, R., Heinsius, F. H., Held, T., Holtmann, T., Keshk, I., Koch, H., Kopf, B., Kuhlmann, M., Kümmel, M., Küßner, M., Li, J., Mustafa, A., Pelizäus, M., Pitka, A., Reher, J., Reicherz, G., Richter, M., Schnier, C., Sohl, L., Steinke, M., Triffterer, T., Wenzel, C., Wiedner, U., Denizli, H., Er, N., Beck, R., Hammann, C., Hartmann, J., Ketzer, B., Müllers, J., Rossbach, M., Salisbury, B., Schmidt, C., Thoma, U., Urban, M., Bianconi, A., Bragadireanu, M., Pantea, D., Domagala, M., Filo, G., Lisowski, E., Lisowski, F., Michałek, M., Poznański, P., Płażek, J., Korcyl, K., Kozela, A., Lebiedowicz, P., Pysz, K., Schäfer, W., Szczurek, A., Fiutowski, T., Idzik, M., Swientek, K., Terlecki, P., Korcyl, G., Lalik, R., Malige, A., Moskal, P., Nowakowski, K., Przygoda, W., Rathod, N., Rudy, Z., Salabura, P., Smyrski, J., Augustin, I., Böhm, R., Lehmann, I., Schmitt, L., Varentsov, V., Al-Turany, M., Belias, A., Deppe, H., Dzhygadlo, R., Flemming, H., Gerhardt, A., Götzen, K., Heinz, A., Jiang, P., Karabowicz, R., Koch, S., Kurilla, U., Lehmann, D., Lühning, J., Lynen, U., Orth, H., Peters, K., Rieger, J., Saito, T., Schepers, G., Schmidt, C. J., Schwarz, C., Schwiening, J., Täschner, A., Traxler, M., Voss, B., Wieczorek, P., Abazov, V., Alexeev, G., Arefiev, V. A., Astakhov, V., Barabanov, M. Yu., Batyunya, B. V., Dodokhov, V. Kh., Efremov, A., Fechtchenko, A., Galoyan, A., Golovanov, G., Koshurnikov, E. K., Lobanov, Y. Yu., Olshevskiy, A. G., Piskun, A. A., Samartsev, A., Shimanski, S., Skachkov, N. B., Skachkova, A. N., Strokovsky, E. A., Tokmenin, V., Uzhinsky, V., Verkheev, A., Vodopianov, A., Zhuravlev, N. I., Branford, D., Watts, D., Böhm, M., Eyrich, W., Lehmann, A., Miehling, D., Pfaffinger, M., Quin, N., Robison, L., Seth, K., Xiao, T., Bettoni, D., Ali, A., Hamdi, A., Himmelreich, M., Krebs, M., Nakhoul, S., Nerling, F., Belousov, A., Kisel, I., Kozlov, G., Pugach, M., Zyzak, M., Bianchi, N., Gianotti, P., Lucherini, V., Bracco, G., Bettner, Y., Bodenschatz, S., Brinkmann, K. T., Brück, L., Diehl, S., Dormenev, V., Düren, M., Erlen, T., Föhl, K., Hahn, C., Hayrapetyan, A., Hofmann, J., Kegel, S., Kesselkaul, M., Köseoglu, I., Kripko, A., Kühn, W., Lange, J. S., Metag, V., Moritz, M., Nanova, M., Novotny, R., Orsich, P., Pereira-de-Lira, J., Peter, M., Sachs, M., Schmidt, M., Schubert, R., Stenzel, H., Straube, M., Strickert, M., Thöring, U., Wasem, T., Wohlfahrt, B., Zaunick, H. G., Tomasi-Gustafsson, E., Glazier, D., Ireland, D., Seitz, B., Deepak, P. N., Kulkarni, A., Kappert, R., Kavatsyuk, M., Loehner, H., Messchendorp, J., Rodin, V., Schakel, P., Vejdani, S., Dutta, K., Kalita, K., Huang, G., Liu, D., Peng, H., Qi, H., Sun, Y., Zhou, X., Kunze, M., Azizi, K., Derichs, A., Dosdall, R., Esmail, W., Gillitzer, A., Goldenbaum, F., Grunwald, D., Jokhovets, L., Kannika, J., Kulessa, P., Orfanitski, S., Pérez Andrade, G., Prasuhn, D., Prencipe, E., Pütz, J., Ritman, J., Rosenthal, E., Schadmand, S., Schmitz, R., Scholl, A., Sefzick, T., Serdyuk, V., Stockmanns, T., Veretennikov, D., Wintz, P., Wüstner, P., Xu, H., Zhou, Y., Cao, X., Hu, Q., Li, Z., Li, H., Liang, Y., Ma, X., Rigato, V., Isaksson, L., Achenbach, P., Aycock, A., Corell, O., Denig, A., Distler, M., Hoek, M., Lauth, W., Leithoff, H. H., Liu, Z., Merkel, H., Müller, U., Pochodzalla, J., Schlimme, S., Sfienti, C., Thiel, M., Zambrana, M., Ahmed , S., Bleser, S., Bölting, M., Capozza, L., Dbeyssi, A., Ehret, A., Grasemann, P., Klasen, R., Kliemt, R., Maas, F., Maldaner, S., Morales Morales, C., Motzko, C., Noll, O., Pflüger, S., Rodríguez Piñeiro, D., Schupp, F., Steinen, M., Wolff, S., Zimmermann, I., Fedorov, A., Kazlou, D., Korzhik, M., Missevitch, O., Balashoff, A., Boukharov, A., Malyshev, O., Balanutsa, P., Chernetsky, V., Demekhin, A., Dolgolenko, A., Fedorets, P., Gerasimov, A., Golubev, A., Goryachev, V., Kantsyrev, A., Kirin, D. Y., Kristi, N., Ladygina, E., Luschevskaya, E., Matveev, V. A., Panjushkin, V., Stavinskiy, A. V., Basant, K. N., Kumawat, H., Roy, B., Saxena, A., Yogesh, S., Bonaventura, D., Brand, P., Fritzsch, C., Grieser, S., Hargens, C., Hergemöller, A. K., Hetz, B., Hüsken, N., Kellers, J., Khoukaz, A., Bumrungkoh, D., Herold, C., Khosonthongkee, K., Kobdaj, C., Limphirat, A., Manasatitpong, K., Nasawad, T., Pongampai, S., Simantathammakul, T., Srisawad, P., Wongprachanukul, N., Yan, Y., Yu, C., Zhang, X., Zhu, W., Blinov, A. E., Kononov, S., Kravchenko, E. A., Antokhin, E., Barnyakov, A. Yu., Beloborodov, K., Blinov, V. E., Kuyanov, I. A., Pivovarov, S., Pyata, E., Tikhonov, Y., Kunne, R., Ramstein, B., Hunter, G., Lattery, M., Pace, H., Boca, G., Duda, D., Finger, M., Finger, Jr., M., Kveton, A., Pesek, M., Peskova, M., Prochazka, I., Slunecka, M., Volf, M., Gallus, P., Jary, V., Korchak, O., Marcisovsky, M., Neue, G., Novy, J., Tomasek, L., Tomasek, M., Virius, M., Vrba, V., Abramov, V., Bukreeva, S., Chernichenko, S., Derevschikov, A., Ferapontov, V., Goncharenko, Y., Levin, A., Maslova, E., Melnik, Y., Meschanin, A., Minaev, N., Mochalov, V., Moiseev, V., Morozov, D., Nogach, L., Poslavskiy, S., Ryazantsev, A., Ryzhikov, S., Semenov, P., Shein, I., Uzunian, A., Vasiliev, A., Yakutin, A., Roy, U., Yabsley, B., Belostotski, S., Fedotov, G., Gavrilov, G., Izotov, A., Manaenkov, S., Miklukho, O., Zhdanov, A., Atac, A., Bäck, T., Cederwall, B., Makonyi, K., Preston, M., Tegner, P. E., Wölbing, D., Gandhi, K., Rai, A. K., Godre, S., Crede, V., Dobbs, S., Eugenio, P., Lersch, D., Calvo, D., De Remigis, P., Filippi, A., Mazza, G., Rivetti, A., Wheadon, R., Bussa, M. P., Spataro, S., Iazzi, F., Lavagno, A., Martin, A., Akram, A., Calen, H., Ikegami Andersson, W., Johansson, T., Kupsc, A., Marciniewski, P., Papenbrock, M., Regina, J., Schönning, K., Wolke, M., Diaz, J., Pothodi Chackara, V., Chlopik, A., Kesik, G., Melnychuk, D., Tarasiuk, J., Wojciechowski, M., Wronka, S., Zwieglinski, B., Amsler, C., Bühler, P., Kratochwil, N., Marton, J., Nalti, W., Steinschaden, D., Widmann, E., Zimmermann, S., and Zmeskal, J.
- Published
- 2021
- Full Text
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49. Study of excited ΞP¯ baryons with the ΞP¯ANDA detector
- Author
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Barucca, G., Davì, F., Lancioni, G., Mengucci, P., Montalto, L., Natali, P. P., Paone, N., Rinaldi, D., Scalise, L., Krusche, B., Steinacher, M., Liu, Z., Liu, C., Liu, B., Shen, X., Sun, S., Zhao, G., Zhao, J., Albrecht, M., Alkakhi, W., Bökelmann, S., Coen, S., Feldbauer, F., Fink, M., Frech, J., Freudenreich, V., Fritsch, M., Grochowski, J., Hagdorn, R., Heinsius, F. H., Held, T., Holtmann, T., Keshk, I., Koch, H., Kopf, B., Kümmel, M., Küßner, M., Li, J., Linzen, L., Maldaner, S., Oppotsch, J., Pankonin, S., Pelizä, M., Pflüger, S., Reher, J., Reicherz, G., Schnier, C., Steinke, M., Triffterer, T., Wenzel, C., Wiedner, U., Denizli, H., Er, N., Keskin, U., Yerlikaya, S., Yilmaz, A., Beck, R., Chauhan, V., Hammann, C., Hartmann, J., Ketzer, B., Müllers, J., Salisbury, B., Schmidt, C., Thoma, U., Urban, M., Bianconi, A., Bragadireanu, M., Pantea, D., Domagala, M., Filo, G., Lisowski, E., Lisowski, F., Michałek, M., Poznański, P., Płażek, J., Korcyl, K., Lebiedowicz, P., Pysz, K., Schäfer, W., Szczurek, A., Firlej, M., Fiutowski, T., Idzik, M., Moron, J., Swientek, K., Terlecki, P., Korcyl, G., Lalik, R., Malige, A., Moskal, P., Nowakowski, K., Przygoda, W., Rathod, N., Salabura, P., Smyrski, J., Augustin, I., Böhm, R., Lehmann, I., Schmitt, L., Varentsov, V., Al-Turany, M., Belias, A., Deppe, H., Dzhygadlo, R., Flemming, H., Gerhardt, A., Götzen, K., Heinz, A., Jiang, P., Karabowicz, R., Koch, S., Kurilla, U., Lehmann, D., Lühning, J., Lynen, U., Orth, H., Peters, K., Schepers, G., Schmidt, C. J., Schwarz, C., Schwiening, J., Täschner, A., Traxler, M., Voss, B., Wieczorek, P., Abazov, V., Alexeev, G., Barabanov, M. Yu., Dodokhov, V. Kh., Efremov, A., Fechtchenko, A., Galoyan, A., Golovanov, G., Koshurnikov, E. K., Lobanov, Y. Yu., Olshevskiy, A. G., Piskun, A. A., Samartsev, A., Shimanski, S., Skachkov, N. B., Skachkova, A. N., Strokovsky, E. A., Tokmenin, V., Uzhinsky, V., Verkheev, A., Vodopianov, A., Zhuravlev, N. I., Watts, D., Böhm, M., Eyrich, W., Lehmann, A., Miehling, D., Pfaffinger, M., Seth, K., Xiao, T., Ali, A., Hamdi, A., Himmelreich, M., Krebs, M., Nakhoul, S., Nerling, F., Gianotti, P., Lucherini, V., Bracco, G., Bodenschatz, S., Brinkmann, K. T., Brück, L., Diehl, S., Dormenev, V., Düren, M., Erlen, T., Hahn, C., Hayrapetyan, A., Hofmann, J., Kegel, S., Khalid, F., Köseoglu, I., Kripko, A., Kühn, W., Metag, V., Moritz, M., Nanova, M., Novotny, R., Orsich, P., Pereira-de-Lira, J., Sachs, M., Schmidt, M., Schubert, R., Strickert, M., Wasem, T., Zaunick, H. G., Tomasi-Gustafsson, E., Glazier, D., Ireland, D., Seitz, B., Kappert, R., Kavatsyuk, M., Loehner, H., Messchendorp, J., Rodin, V., Kalita, K., Huang, G., Liu, D., Peng, H., Qi, H., Sun, Y., Zhou, X., Kunze, M., Azizi, K., Olgun, A. T., Tavukoglu, Z., Derichs, A., Dosdall, R., Esmail, W., Gillitzer, A., Goldenbaum, F., Grunwald, D., Jokhovets, L., Kannika, J., Kulessa, P., Orfanitski, S., Pérez-Andrade, G., Prasuhn, D., Prencipe, E., Pütz, J., Ritman, J., Rosenthal, E., Schadmand, S., Schmitz, R., Scholl, A., Sefzick, T., Serdyuk, V., Stockmanns, T., Veretennikov, D., Wintz, P., Wüstner, P., Xu, H., Zhou, Y., Cao, X., Hu, Q., Liang, Y., Rigato, V., Isaksson, L., Achenbach, P., Corell, O., Denig, A., Distler, M., Hoek, M., Lauth, W., Leithoff, H. H., Merkel, H., Müller, U., Petersen, J., Pochodzalla, J., Schlimme, S., Sfienti, C., Thiel, M., Bleser, S., Bölting, M., Capozza, L., Dbeyssi, A., Ehret, A., Klasen, R., Kliemt, R., Maas, F., Motzko, C., Noll, O., Piñeiro, D. Rodríguez, Schupp, F., Steinen, M., Wolff, S., Zimmermann, I., Kazlou, D., Korzhik, M., Missevitch, O., Balanutsa, P., Chernetsky, V., Demekhin, A., Dolgolenko, A., Fedorets, P., Gerasimov, A., Golubev, A., Kantsyrev, A., Kirin, D. Y., Kristi, N., Ladygina, E., Luschevskaya, E., Matveev, V. A., Panjushkin, V., Stavinskiy, A. V., Balashoff, A., Boukharov, A., Bukharova, M., Malyshev, O., Vishnevsky, E., Bonaventura, D., Brand, P., Hetz, B., Hüsken, N., Kellers, J., Khoukaz, A., Klostermann, D., Mannweiler, C., Vestrick, S., Bumrungkoh, D., Herold, C., Khosonthongkee, K., Kobdaj, C., Limphirat, A., Manasatitpong, K., Nasawad, T., Pongampai, S., Simantathammakul, T., Srisawad, P., Wongprachanukul, N., Yan, Y., Yu, C., Zhang, X., Zhu, W., Antokhin, E., Barnyakov, A. Yu., Beloborodov, K., Blinov, V. E., Kuyanov, I. A., Pivovarov, S., Pyata, E., Tikhonov, Y., Blinov, A. E., Kononov, S., Kravchenko, E. A., Lattery, M., Boca, G., Duda, D., Finger, M., Finger, Jr., M., Kveton, A., Pesek, M., Peskova, M., Prochazka, I., Slunecka, M., Volf, M., Gallus, P., Jary, V., Korchak, O., Marcisovsky, M., Neue, G., Novy, J., Tomasek, L., Tomasek, M., Virius, M., Vrba, V., Abramov, V., Bukreeva, S., Chernichenko, S., Derevschikov, A., Ferapontov, V., Goncharenko, Y., Levin, A., Maslova, E., Melnik, Y., Meschanin, A., Minaev, N., Mochalov, V., Moiseev, V., Morozov, D., Nogach, L., Poslavskiy, S., Ryazantsev, A., Ryzhikov, S., Semenov, P., Shein, I., Uzunian, A., Vasiliev, A., Yakutin, A., Belostotski, S., Fedotov, G., Izotov, A., Manaenkov, S., Miklukho, O., Preston, M., Tegner, P. E., Wölbing, D., Cederwall, B., Gandhi, K., Rai, A. K., Godre, S., Crede, V., Dobbs, S., Eugenio, P., Calvo, D., De Remigis, P., Filippi, A., Mazza, G., Wheadon, R., Iazzi, F., Lavagno, A., Bussa, M. P., Spataro, S., Akram, A., Calen, H., Ikegami Andersson, W., Johansson, T., Kupsc, A., Marciniewski, P., Papenbrock, M., Regina, J., Rieger, J., Schönning, K., Wolke, M., Chlopik, A., Kesik, G., Melnychuk, D., Tarasiuk, J., Wronka, S., Zwieglinski, B., Amsler, C., Bühler, P., Marton, J., and Zimmermann, S.
- Published
- 2021
- Full Text
- View/download PDF
50. Glanz wie vom ersten Tage: Schöpfungsgesänge
- Author
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Dr. Josefine Müllers
- Published
- 2019
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