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Your search keyword '"A. K. Raghupathy"' showing total 12 results
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12 results on '"A. K. Raghupathy"'

2. Health-related quality of life and its effect on TB treatment outcomes

Author

Natasha S. Hochberg, L Subitha, Padmini Salgame, C. R. Horsburgh, Yuvaraj Krishnamoorthy, Sonali Sarkar, K Ezhumalai, N Roy, Jerrold J. Ellner, Sathish Rajaa, K Raghupathy, S Madhusudhanan, Senbagavalli Prakash Babu, and Selby Knudsen

Subjects
Pulmonary and Respiratory Medicine, Health related quality of life, medicine.medical_specialty, Tuberculosis, business.industry, Treatment outcome, MEDLINE, medicine.disease, Treatment Outcome, Infectious Diseases, Quality of life (healthcare), Tuberculosis, Multidrug-Resistant, Quality of Life, medicine, Humans, Intensive care medicine, business, Tuberculosis, Pulmonary, Tb treatment
Published
2021
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4. Abnormal photoreceptor outer segment development and early retinal degeneration in kif3a mutant zebrafish

Author

Rakesh K, Raghupathy, Xun, Zhang, Reem H, Alhasani, Xinzhi, Zhou, Margaret, Mullin, James, Reilly, Wenchang, Li, Mugen, Liu, and Xinhua, Shu

Subjects
Melanosomes, Base Sequence, Retinal Degeneration, Intracellular Space, Gene Expression Regulation, Developmental, Kinesins, Zebrafish Proteins, Retinal Photoreceptor Cell Outer Segment, Protein Transport, Phenotype, Caffeine, Mutation, In Situ Nick-End Labeling, Animals, Cryoultramicrotomy, Zebrafish
Abstract

Photoreceptors are highly specialized sensory neurons that possess a modified primary cilium called the outer segment. Photoreceptor outer segment formation and maintenance require highly active protein transport via a process known as intraflagellar transport. Anterograde transport in outer segments is powered by the heterotrimeric kinesin II and coordinated by intraflagellar transport proteins. Here, we describe a new zebrafish model carrying a nonsense mutation in the kinesin II family member 3A (kif3a) gene. Kif3a mutant zebrafish exhibited curved body axes and kidney cysts. Outer segments were not formed in most parts of the mutant retina, and rhodopsin was mislocalized, suggesting KIF3A has a role in rhodopsin trafficking. Both rod and cone photoreceptors degenerated rapidly between 4 and 9 days post fertilization, and electroretinography response was not detected in 7 days post fertilization mutant larvae. Loss of KIF3A in zebrafish also resulted in an intracellular transport defect affecting anterograde but not retrograde transport of organelles. Our results indicate KIF3A plays a conserved role in photoreceptor outer segment formation and intracellular transport.

Published
2016

5. Artificial intelligence in boiler control

Author

Rajiv Kumar Yadav and K. Raghupathy

Subjects
Flexibility (engineering), Engineering, Neuro-fuzzy, business.industry, Generalization, Control engineering, Fault tolerance, Boiler control, Fuzzy logic, GeneralLiterature_MISCELLANEOUS, Fuzzy electronics, Steam system, Artificial intelligence, business
Abstract

Artificial Intelligence (AI) techniques are becoming useful as alternate approaches to conventional techniques. They have been used to solve complicated practical problems and now a day is very popular. They can learn from examples, fault tolerant in the sense they are able to handle noisy and incomplete data and once trained can perform faster prediction and generalization. AI based systems are used mainly because of their symbolic reasoning, flexibility and explanation capabilities. This paper briefly presents the main AI techniques and outlines an application in boiler control. Master controller is required for a steam generating system having multiple boilers operating in parallel. AI technique of Fuzzy logic controller is proposed as master controller. The optimum performance of individual boilers is achieved by the master controller meeting the varying load demands of the steam system.

Published
2015
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6. Abstracts

Author

C. A. Botero, C. E. Smith, C. Holbrook, A. C. Pinchak, David Johnson, Dorothy Thomson, Taras Mycyk, M. Burbridge, Irvin Mayers, nR. W. M. Wahba, F. Belque, S. J. Kleiman, Steven Parker, Peter Cox, Helen Holtby, Lawrence Roy, Marc A. St-Amand, John M. Murkin, Donna Baird, Donal B. Downey, Alan H. Menkis, Fan Yang, Éric Troncy, Martin Francœur, Marc Charbonneau, Patrick Vinay, Gilbert Blaise, William M. Splinter, David J. Roberts, Elliot J. Rhine, Helen B. MacNeill, Craig W. Reid, William PS McKay, Miklavs Erjavec, Benjamin W. S. McKay, Peter H. Gregson, Travis Blanchet, Guy Kember, Josée Lavoie, Daniel Vischoff, Louise Cyrenne, Edith Villeneuve, Pierre Williot, A. K. Raghupathy, R. Haug, B. Punjabi, F. Ditzig, Howard Melnik, Michael J. Tessler, L. Jill Krasner, David M. Corda, Kal Solanki, A. Joseph Layon, T. James Gallagher, Daniel P. Stoltzfus, Shannon L. Rabuka, Carol A. Moote, Robert J. B. Chen, Doreen A. Yee, Ellen Harrington, Beverley A. Orser, D. Mitch Giffin, Kenneth W. Gow, P. Terry Phang, Keith R. Walley, C. Brian Warriner, Matthew H. Cohen, Andrew J. Klahsen, Deirdre O’Reilly, John McBride, Margaret Ballantyne, Blair D. Goranson, Scott Lang, William N. Dust, Jeff McKerrell, Guy Martin, René Martin, Daniel Martin, Philippe Valet, Jean-Pierre Tétrault, Caroline Dagenais, Martine Pirlet, Dominique Dansereau, Pedro D’Orléans-Justes, Agnès Jankowska, Yves Veillette, Angela L. Mathieson, Howard Intrater, Lionel Cruickshank, P. C. Duke, B. Y. Ong, Vincent Woo, Donna Schimnowski, Sharon Trosky, Linda Dalton, Ibrahim Zabani, Colin R. Chilvers, Himat Vaghadia, Pamela M. Merrick, Ibrahim Kashkari, Hossam Al-Oufi, D. Jolly, B. T. Finucane, Wolfgang Weyland, Ulrich Fritz, Heike Landmann, Ingrid Schumacher, Michael English, Dietrich Kettler, Catherine M. Duffy, Pirjo H. Manninen, Frances Chung, Shanthini Sundar, Emilio B. Lobato, Orlando Florete, Glenn B. Paige, Thierry Daloze, Daniel A. Chartrand, Denis St-Laurent, Gordon S. Fox, Murray L. Rice, D. John Doyle, George A. Volgyesi, Joseph A. Fisher, Arthur Slutsky, Igor Salazkin, Karen A. Brown, Pradeep Kulkarni, Bibiana Cujec, Randy McCuaig, Tom Hurst, David Antecol, François Bellemare, Jacques Couture, Manon Marchand, Peter McNeil, Orlando Hung, Lily M. Ho-Tai, J. Hugh Devitt, Alva G. Noel, Michael P. O’Donnell, Robert J. Greenhow, Frank W. Cervenko, Brian Milne, Mark D. Peterson, Ian R. Thomson, Robert J. Hudson, Morley Rosenbloom, Michael Moon, Jitender Sareen, H. Locke Bingham, Steven B. Backman, Reuben D. Stein, C. Polosa, Michael Tessler, Salvatore M. Spadafora, John G. Fuller, Lisa Kim, Keyvan Karkouti, D. Keith Rose, Lorraine E. Ferris, DK Rose, MM Cohen, F. E. Ralley, B. DeVarennes, M. Robitaille, Norman Searle, Raymond Martineau, Peter Conzen, A. Al-Hasani, Tom Ebert, Michael Muzi, Jean-François Hardy, Sylvain Bélisle, André Couturier, Danielle Robitaille, Micheline Roy, Lyne Gagnon, Elisabeth J. Avraamides, P. J. Dryden, J. P. O’Connor, W. R. E. Jamieson, I. Reid, D. Ansley, H. Sadeghi, L. H. Burr, A. I. Munro, P. M. Merrick, Mark Benaroia, Andrew Baker, C. David Mazer, Lee Errett, Luc Frenette, Jerry Cox, Donna Kerns, Steve Pearce, David Mark, Paul McDonagh, Lulz DeLlma, Howard Nathan, Jean-Yves Dupuls, J.Earl Wynands, G. C. Moudgil, J. G. Johnson, G. M. Moudgil, Richard I. Hall, Connie MacLaren, M. J. Ali, M. Ballantyne, D. Norris, Stephen D. Beed, Eugene A. Menard, Leon P. Noel, Gary G. Bonn, William Clarke, H. Marion Gould, Leslie E. Hall, Philippe Bernard, Juan Bass, Ramona A. Kearney, Cheryl A. Mack, Lucy M. Entwistle, Joan C. Bevan, Andrew J. Macnab, Guy Veall, Colin Marsland, Craig R. Ries, Shahnaz K. Hamid, Ian R. Selby, Nancy Sikich, Elizabeth Hsu, Patricia McCarthy, Ching-Yue Yang, Wun-Chin Wu, Jiunn-Jye Huang, Shyu-Yin Chen, Hsiang-Ning Luk, Chok-Yung Chai, Gina K. Lafreniere, Donald G. Brunet, Joel L. Parlow, Hossam El-Beheiry, Aviv Ouanounou, Mary Morris, Peter Carlen, Pamela J. Morgan, Roger Chapados, Marlene Gauthier, John W. D. Knox, Jacques LeLorier, Roddy Lin, Keith Rose, Bernadette Garvey, Robert McBrobm, L. C. McAdam, J. F. MacDonald, B. A. Orser, Georgios koutsoukos, Susan Belo, Christopher A. Chin, Brendan O’Hare, Jerrold Lerman, Junko Endo, Arthur E. Schwartz, Oktavijan Minanov, J. Gilbert Stone, David C. Adams, Aqeel A. Sandhu, Mark E. Pearson, William L. Young, Robert E. Michler, Ernest Cutz, Matt M. Kurrek, Marsha M. Cohen, Kevin Fish, Pamela Fish, Patricia Murphy, Donald Fung, Alva Noel, John-Paul Szalai, Ari Robicsek, Joshua Rucker, Joshua Kruger, Mark Slutsky, Leeor Sommer, Jeff Silverman, Jodi Dickstein, Viren Naik, Douglas J. Hemphill, Regina Kurian, Khursheed N. Jeejeebhoy, Osama A. Alahdal, N. H. Badner, W. E. Komar, R. Bhandari, R. Craen, D. Cuillerier, W. B. Dobkowski, M. H. Smith, A. N. Vannelli, R. B. Bourne, C. H. Rorabeck, J. A. Doyle, Antoinette Corvo, Richard M. Wahba, Nathalie Scheffer, John Y. C. Tsang, Brad A. Brush, N. Q. N’Guyen, C. Orain, S. Tougui, G. Lavenac, D. Milon, Ewan D. Ritchie, Doris Tong, Andrew Norris, Anthony Miniaci, Santhira D. Vairavanathan, Timothy FitzPatrick, Mark Stafford-Smith, Ken Kardash, Toula Trihas, Simcha J. Kleiman, Michel Rossignol, Dominique Bérard, Brent Martel, J. P. Tétrault, Peter G. Lunt, Dennis W. Coombs, Stephen Halpern, Elizabeth A. Peter, Patricia Janssen, Jill Mahy, M. Joanne Douglas, Caroline S. Grange, Timothy J. Adams, Louis Wadsworth, Holly Muir, Romesh Shukla, Desmond Writer, Richard McLaren, Robert Liston, Don Paetkau, Bill Y. Ong, Ron Segstro, Judy Littleford, Cristina Hurtado, Ananthan Krishnathas, Marcelo Lannes, Joanne Fortier, Jun Su, Rubini Jeganathan, and Suzanne Vaillancourt

Subjects
Anesthesiology and Pain Medicine, General Medicine
Published
1996
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8. Improved curve tracing in images

Author

T.W. Parks and K. Raghupathy

Subjects
business.industry, Computer science, Image processing, Computer vision, Image segmentation, Artificial intelligence, Tracing, business, Feature detection (computer vision)
Abstract

This paper begins with a description of the curve tracing problem and compares it with curve extraction, a fundamentally different problem. Issues concerning curve tracing are addressed. We discuss a good curve tracing algorithm proposed by Carsten Steger and improve this method to suit the goals of curve tracing. Results show that the improved algorithm emulates human perception by using both global and local features.

Published
2004
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9. Genome-wide pathway analysis and visualization using gene expression data

Author

Sudeshna Adak, Manish P. Kurhekar, K. Raghupathy, and S. Jhunjhunwala

Subjects
Ribosomal Proteins, Genome, Databases, Factual, Computer science, Gene Expression, Computational biology, Pathway analysis, computer.software_genre, Oxidative Phosphorylation, Visualization, Gene expression profiling, Microarray gene expression, Gene expression, Animals, Data mining, computer, Glycolysis, Oligonucleotide Array Sequence Analysis
Abstract

Visualization of results for high performance computing pose special problems due to the complexity and the volume of data these systems manipulate. We present an approach for visualization of c-DNA microarray gene expression data in metabolic and regulatory pathways using multi-resolution animation at different levels of detail. We describe three scoring functions to characterize pathways at the transcriptional level based on gene expression, coregulation and cascade effect. We also assess the significance of each pathway score on the basis of their biological connotation.

Published
2002

10. Intrapartum fetal monitoring using fetal ECG ST segment analysis (STAN) is associated with a reduction in obstetric interventions

Author

K Orr, AE Nicoll, and K Raghupathy

Subjects
medicine.medical_specialty, Pregnancy, business.industry, Obstetrics, Reproductive medicine, Obstetrics and Gynecology, Metabolic acidosis, General Medicine, medicine.disease, Fetal monitoring, Fetal ecg, Obstetrics and gynaecology, Pediatrics, Perinatology and Child Health, medicine, ST segment, Obstetric interventions, business
Abstract

Background Intrapartum fetal monitoring with STAN has the potential to reduce maternal and neonatal morbidity and decrease obstetric interventions. Intrapartum monitoring with STAN was introduced in Ninewells Hospital, Dundee in October 2007. Aim To assess whether increased use of STAN was associated with a reduction in fetal blood sampling (FBS). Furthermore our aims were to determine the rates of operative delivery and neonatal metabolic acidosis. Methods Women who delivered after 37 weeks between 01 January 2007 and 31 December 2009 were included. All cardiotocograph recordings were reviewed. Information about outcomes was obtained from the local maternity database (Torex Protos Evolution, version 3.5.19). Results Intrapartum monitoring with STAN increased from 45/188 (23.9%) in October 2007 to 105/148 (70.9%) in December 2009 (p Conclusion Intrapartum monitoring with STAN has increased and this has been associated with a significant reduction in FBS and operative vaginal deliveries at term. However there has been no significant change in rates of severe neonatal metabolic acidosis.

Published
2010
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11. Electroreduction of 3-cyanopyridine

Author

H.V.K. Udupa, V. Krishnan, and K. Raghupathy

Subjects
Primary (chemistry), Chemistry, Inorganic chemistry, Graphite, Electrolyte, Palladium black, Nuclear chemistry
Abstract

3-Aminomethylpyridine and some of its derivatives are either drug materials or insecticides. A simple electrolytic reduction method for the preparation of 3-aminomethylpyridine dihydrochloride using deposited palladium black over graphite is described. This technique should be generally useful for the preparation of primary amines.

Published
1978
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