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The Peditrol is a novel hands-free irrigation device that delivers a bolus of irrigant through the ureteroscope when the foot pedal is deployed. The purpose of this study was to compare the flow and pressures created by the Peditrol with those of commonly used methods of irrigation.Flows through a flexible 6.9F Olympus ureteroscope (F-URS) and a 7.5F semirigid ACMI ureteroscope (S-URS) were measured in duplicate with the working channel empty and with a 2.2F Nitinol basket or a laser fiber in the working port. Irrigant flow was pressurized by gravity drainage at 100 cm H(2)O (GI), pressurized irrigant bag at 300 cm H(2)O (PI), handheld 60-cc syringe (HS), and the Peditrol. A 20-gauge angiocatheter was placed through the parenchyma into the renal pelvis of an ex-vivo cadaveric porcine kidney and attached to a pressure transducer. Pressures were measured in triplicate using the same irrigation techniques.With a basket or 200-microm laser fiber in the working port of the F-URS, Peditrol mean flows were superior to those of PI (3.3 and 6.3 times, respectively; P0.001) but similar to those of HS (0.7 to 1.1 times). All irrigation types resulted in intrarenal pressures greater than gravity irrigation (P0.05). The Peditrol demonstrated intrapelvic pressures40 cm H(2)O when used with a 12/14F ureteral access sheath (AS). Without an AS, the intrapelvic pressure reached 92 cm H(2)O, similar to the pressures reached with the S-URS under various irrigation conditions (84-287 cm H(2)O) and comparable to the HS method through the F-URS (97 cm H(2)O).The Peditrol irrigation device generates superior flow through an F-URS compared with GI or PI, particularly with an instrument in the working port. Intrarenal pressures when used with an F-URS and AS are low. When an AS is not used, the intrarenal pressure is similar to or lower than pressures obtained using an S-URS with different irrigation modalities.

Study objective Systemic administration of s-agonist and anticholinergic drugs markedly impair normal autonomic heart rate control. The purpose of this study was to quantify and compare the effects of therapeutic doses of inhaled albuterol and ipratropium on autonomic control of the cardiovascular system. Design Randomized, double-blind, placebo-controlled, crossover design study. Setting Tertiary-care hospital. Subjects Twelve healthy male volunteers. Interventions Subjects self-administered four puffs through a spacer device from one of three identical inhalers containing albuterol (100 µg per puff), ipratropium (20 µg per puff), or placebo in three different testing sessions. Measurements ECG and noninvasive continuous BP traces were recorded at baseline and from 45 to 75 min after administration of the drug. Autonomic control of the cardiovascular system was quantified by analysis of spontaneous baroreflex sensitivity and power spectral analysis of heart rate variability. Results Neither albuterol nor ipratropium caused a significant alteration in baroreflex sensitivity, normalized low-power frequency, or normalized high-power frequency. No adverse effects were reported by subjects. Conclusions Inhalation of four puffs of albuterol (400 µg) or ipratropium (80 µg) does not alter the autonomic control of the cardiovascular system in young, healthy male subjects.

The use of stone baskets for repositioning of stones or removal of fragment in conjunction with ureterorenoscopy has become widespread. We tested the performance of the ACMI Sur-Catch NT, Bard Dimension, Boston Scientific Zero-tip, and Cook N-Circle in a pig kidney model of flexible ureterorenoscopy.Opening characteristics of the basket were measured with mechanical calipers at 1-mm increments and compared with published reports to ensure the tested baskets were representative. Pig kidneys were placed in a basin and the ureters secured with a suture to a weight for stability. Flexible renoscopy was performed using a 16F flexible cystonephroscope. An 8-mm calculus was placed in the lower pole. Using each of four designs, the time necessary to grasp the stone, time to release the stone, and total time to move a stone from the lower-pole calix to the upper-pole were recorded. Total time experiments were repeated six times with each basket by three surgeons for a total of 18 attempts, and catch-and-release experiments were repeated six times by four surgeons for a total of 24 attempts per basket.The Sur-Catch was significantly slower for catch and release (P0.001) and total time; P0.05) compared with all other baskets. There were no differences between the other baskets in either catch, release, or total times. There was no difference between surgeons (P0.0634) or between attempts one through six (P = 0.538).Baskets with added complexity of the wire configurations (Sur-Catch) or a deflectable-wire mechanism (Dimension) offer no advantages and may slow capture and release of stones.

While laparoscopy represents an increasingly important aspect of operative urology, the experience of Canadian urology trainees is poorly defined. The purpose of this study was to determine the level of laparoscopic training of Canadian urology trainees during residency as well as their comfort level with various laparoscopic techniques.An e-mail-and web-based questionnaire was administered to the two most recent cohorts of Canadian-trained urologists (residencies completed in 2003 or 2004). A total of 50 questionnaires were sent. Overall laparoscopic experience and experience with specific laparoscopic tasks (e.g. colonic mobilization) were assessed. Subjects also reported on their relative comfort level (Likert scale of 1 to 5) with various laparoscopic procedures and tasks. Finally, attitudes towards the future role of laparoscopy in the practice of urology were determined.Thirty-six individuals (72%) responded to the questionnaire. Of the respondents, 28 (78%) were performing fellowships; of those pursuing fellowship training, 13 (36%) involved laparoscopy. Thirty-five respondents (97%) had received some laparoscopic exposure during residency; 29 (81%) had mobilized the colon, spleen or liver and 27 (75%) had dissected the renal vessels. Only 7 out of 33 respondents (21%) felt that their residency adequately prepared them to perform laparoscopy independently. There were no significant differences between the responses of the two cohorts.Most Canadian urology trainees are being exposed to laparoscopy, but more exposure is required in order to perform laparoscopy in practice. Many residents still require fellowship training to become facile in laparoscopy.

Smaller semirigid ureteroscopes with large working channels and excellent optics are widely available. Ureteroscopic treatment of upper-ureteral stones has become increasingly popular, although flexible ureteroscopy is more frequently the method of choice. Access to the upper ureter with a semirigid ureteroscope (SR-URS) can be challenging and hazardous, especially when negotiating the iliac vessels. We sought to determine whether lower-abdominal pressure (LAP) facilitated SR-URS access to the upper ureter for safe laser lithotripsy.Thirty-two consecutive patients who underwent ureteroscopic management of upper- ureteral stones were evaluated. Twenty-four (75%) were male; seventeen (53%) had a right-sided stone. The mean largest stone diameter was 10.2 +/- 4.6 mm. These 32 patients were compared with a matched cohort of patients who underwent SR-URS procedures without the use of LAP.Access to the upper ureter was possible in 30 patients (94%). The LAP was helpful in 18 patients (56%): it facilitated passage of the SR-URS in 16 patients (50%) and laser fiber placement in 11 cases (34%). Access to the upper ureter was possible in all women. The mean operative time was 54 minutes in the LAP group and 75 minutes in the matched cohort without LAP (P = 0.026). There were no significant deformities of the SR-URS and no complications.Contrary to popular practice, the upper ureter can be accessed safely and efficiently with a 7.5F SR-URS in nearly all patients. Lower-abdominal pressure can be helpful to negotiate passage of the endoscope over the iliac vessels or to place the laser fiber on stones.

Vaso-cutaneous fistulae occur rarely after vasectomy. We report three cases encountered in our hospital over the last 18 years and recommend technical considerations to avoid this complication.

While combined percutaneous and endoscopic techniques have been described previously as a means of dealing with the distally strictured ureter, this report confirms that these approaches can also be used successfully in the management of the very distally ligated ureter in the early post-injury period.

Metabolic evaluation is indicated in stone formers to identify and subsequently modify risk factors for nephrolithiasis. Some believe that serum phosphate may be an important indicator of nephrolithiasis risk. We determined whether serum phosphate is an independent risk factor for recurrent calcium stone formation and whether it may be used as an early marker for occult disease, such as hyperparathyroidism.The charts of all patients with regular long-term stone clinic followup were reviewed. Initial serum phosphate levels were compared with stone recurrence, complications due to stones, initial visit urinary laboratory values and the medical diagnoses made during followup. Unpaired 2-sample t tests, and correlation and logistic regression analyses were performed with statistical significance at p0.05.Data were available on 51 men and 25 women 22 to 74 years old (mean age 52). Of the patients 50 were recurrent and 26 were single stone formers. Serum phosphate levels were lower in women than in men. No consistent associations existed between initial or future serum phosphate levels and stone recurrence, complications from stones, urinary values or other medical diagnoses made during followup.Serum phosphate does not appear to be an independent risk factor for urinary tract stone recurrence or complications, or a reliable early predictor of occult disease.