118,615 results on '"A Johansen"'
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2. Complex organisational factors influence multidisciplinary care for patients with hip fractures: a qualitative study of barriers and facilitators to service delivery
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F Fox, S Drew, CL Gregson, R Patel, TJS Chesser, A Johansen, MK Javaid, XL Griffin, and R Gooberman-Hill
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Hip fracture ,Qualitative ,Service delivery ,Multidisciplinary care ,Care pathway ,Communication ,Diseases of the musculoskeletal system ,RC925-935 - Abstract
Abstract Background Hip fractures are devastating injuries, with high health and social care costs. Despite national standards and guidelines, substantial variation persists in hospital delivery of hip fracture care and patient outcomes. This qualitative study aimed to identify organisational processes that can be targeted to reduce variation in service provision and improve patient care. Methods Interviews were conducted with 40 staff delivering hip fracture care in four UK hospitals. Twenty-three anonymised British Orthopaedic Association reports addressing under-performing hip fracture services were analysed. Following Thematic Analysis of both data sources, themes were transposed onto domains both along and across the hip fracture care pathway. Results Effective pre-operative care required early alert of patient admission and the availability of staff in emergency departments to undertake assessments, investigations and administer analgesia. Coordinated decision-making between medical and surgical teams regarding surgery was key, with strategies to ensure flexible but efficient trauma lists. Orthogeriatric services were central to effective service delivery, with collaborative working and supervision of junior doctors, specialist nurses and therapists. Information sharing via multidisciplinary meetings was facilitated by joined up information and technology systems. Service provision was improved by embedding hip fracture pathway documents in induction and training and ensuring their consistent use by the whole team. Hospital executive leadership was important in prioritising hip fracture care and advocating service improvement. Nominated specialty leads, who jointly owned the pathway and met regularly, actively steered services and regularly monitored performance, investigating lapses and consistently feeding back to the multidisciplinary team. Conclusion Findings highlight the importance of representation from all teams and departments involved in the multidisciplinary care pathway, to deliver integrated hip fracture care. Complex, potentially modifiable, barriers and facilitators to care delivery were identified, informing recommendations to improve effective hip fracture care delivery, and assist hospital services when re-designing and implementing service improvements.
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- 2023
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3. Asynchronous distributed collision avoidance with intention consensus for inland autonomous ships
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Tran, Hoang Anh, Lauvås, Nikolai, Johansen, Tor Arne, and Negenborn, Rudy R.
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Electrical Engineering and Systems Science - Systems and Control - Abstract
This paper focuses on the problem of collaborative collision avoidance for autonomous inland ships. Two solutions are provided to solve the problem in a distributed manner. We first present a distributed model predictive control (MPC) algorithm that allows ships to directly negotiate their intention to avoid collision in a synchronous communication framework. Moreover, we introduce a new approach to shape the ship's behavior to follow the waterway traffic regulations. The conditional convergence toward a stationary solution of this algorithm is guaranteed by the theory of the Alternating Direction Method of Multipliers (ADMM). To overcome the problem of asynchronous communication between ships, we adopt a new asynchronous nonlinear ADMM and present an asynchronous distributed MPC algorithm based on it. Several simulations and field experiments show that the proposed algorithms can prevent ship collisions even in complex scenarios.
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- 2025
4. The influence of dust growth on the observational properties of circumplanetary discs
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Schulik, Matthäus, Bitsch, Bertram, Johansen, Anders, and Lambrechts, Michiel
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Astrophysics - Earth and Planetary Astrophysics - Abstract
Dust growth is often indirectly inferred observationally in star-forming environments, theoretically predicted to produce mm-sized particles in circumstellar discs, and also presumably witnessed by the predecessors of the terrestrial meteoritic record. For those reasons it is believed that young gas giants under formation in protoplanetary discs with putative circumplanetary discs (CPDs) surrounding them, such as PDS 70c, should be containing mm-sized particles. We model the spectra of a set of CPDs, which we obtained from radiation hydrodynamic simulations at varying Rosseland opacities kappa_R. The kappa_R from the hydrodynamic simulations are matched with consistent opacity sets of ISM-like composition, but grown to larger sizes. Our high kappa_R hydro data nominally corresponds to 10 mum-sized particles, and our low kappa_R-cases correspond to mm-sized particles. We investigate the resulting broad spectral features at first while keeping the overall optical depth in the planetary envelope constant. Dust growth to size distributions dominated by millimeter particles generally results in broad, featureless spectra with black-body like slopes in the far-infrared, while size distributions dominated by small dust develop steeper slopes in the far-infrared and maintain some features stemming from individual minerals. We find that significant dust growth from microns to millimeters can explain the broad features of the PDS 70c data, when upscaling the dust masses from our simulations by x100. Furthermore our results indicate that the spectral range of 30-500 mum is an ideal hunting ground for broadband features arising from the CPD, but that longer wavelengths observed with ALMA can also be used for massive circumplanetary discs, Comment: 12 pages, 8 figures, Accepted to A&A
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- 2025
5. The coexistence of the streaming instability and the vertical shear instability in protoplanetary disks: Scale-dependence of dust diffusion
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Schäfer, Urs, Johansen, Anders, and Flock, Mario
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Astrophysics - Earth and Planetary Astrophysics - Abstract
The vertical shear instability and the streaming instability are two robust sources of turbulence in protoplanetary disks. The former has been found to induce anisotropic turbulence that is stronger in the vertical than in the radial dimension and to be overall stronger compared to the largely isotropic turbulence caused by the streaming instability. In this study, we shed light on the dust diffusion by the vertical shear instability and the streaming instability separately and together, and in particular on the direction- and scale-dependence of the diffusion. To this end, we employ two-dimensional global models of the two instabilities either in isolation or in combination. The vertical shear instability in isolation diffuses dust more strongly in the vertical direction than the streaming instability in isolation, resulting in a wave-shaped dust layer in our two-dimensional simulations. Compared with this large-scale diffusion, though, our study highlights that the vertical shear instability causes substantially weaker or even negligible small-scale diffusion. We validate this result using previously published three-dimensional simulations. In particular when simulating centimetre-sized dust, the undulating dust layer becomes internally razor-thin. In contrast, the diffusion owing to the streaming instability exhibits only a marginal scale-dependence, with the dust layer possessing a Gaussian shape. In models including both instabilities, the undulating mid-plane layer is broadened to a width set by the intrinsic diffusion level caused by the streaming instability., Comment: 15 pages, 8 figures, 2 tables; accepted for publication in Astronomy & Astrophysics
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- 2025
6. The evolution of the flux-size relationship in protoplanetary discs by viscous evolution and radial pebble drift
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Appelgren, Johan, Johansen, Anders, Lambrechts, Michiel, Jørgensen, Jes, van der Marel, Nienke, Ohashi, Nagayoshi, and Tobin, John
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Astrophysics - Earth and Planetary Astrophysics - Abstract
In this paper we study the evolution of radiative fluxes, flux radii and observable dust masses in protoplanetary discs, in order to understand how these depend on the angular momentum budget and on the assumed heat sources. We use a model that includes the formation and viscous evolution of protoplanetary gas discs, together with the growth and radial drift of the dust component. We find that we are best able to match the observed fluxes and radii of class 0/I discs when we assume (i) an initial total angular momentum budget corresponding to a centrifugal radius of 40 au around solar-like stars, and (ii) inefficient viscous heating. Fluxes and radii of class II discs appear consistent with disc models with angular momentum budgets equivalent to centrifugal radii of both 40 au or 10 au for solar like stars, and with models where viscous heating occurs at either full efficiency or at reduced efficiency. During the first 0.5 Myr of their evolution discs are generally optically thick at a wavelength of 1.3 mm. However, after this discs are optically thin at mm-wavelengths, supporting standard means of dust mass estimates. Using a disc population synthesis model, we then show that the evolution of the cumulative evolution of the observable dust masses agrees well with that observed in young star forming clusters of different ages., Comment: 12 pagers, 12 figures
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- 2025
7. Electronic properties of stacking faults in Bernal graphite
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Sarsfield, Patrick Johansen, Slizovskiy, Sergey, Koshino, Mikito, and Fal'ko, Vladimir
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Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
Using the tight-binding model of graphite, incorporating all Slonczewski-Weiss-McClure parameters, we compute the spectrum of two-dimensional states of electrons bound to a stacking fault in Bernal graphite. We find that those bands retain characteristic features of the low-energy bands of a rhombohedral graphene trilayer, which actually represents the lattice structure the fault. Based on the self-consistent analysis of charge and potential distribution across the fault layers, we determine the shape of the Fermi contour for the 2D band, which has the form of three pockets with a hole-like conic dispersion and Dirac points above the Fermi level. The computed frequency of Shubnikov-de Haas oscillations and the cyclotron mass of the fault-bound charge carriers (at the Fermi level) are sufficiently different from the corresponding bulk values in graphite, making such stacking faults identifiable by quantum transport and cyclotron resonance measurements., Comment: 5 pages, 5 figures (main text). 7 pages, 9 figures (supplementary text)
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- 2024
8. UV-processing of icy pebbles in the outer parts of VSI-turbulent disks
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Flores-Rivera, Lizxandra, Lambrechts, Michiel, Gavino, Sacha, Lorek, Sebastian, Flock, Mario, Johansen, Anders, and Mignone, Andrea
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
Icy dust particles emerge in star-forming clouds and are subsequently incorporated in protoplanetary disks, where they coagulate into larger pebbles up to mm in size. In the disk midplane, ices are shielded from UV radiation, but moderate levels of disk turbulence can lift small particles to the disk surface, where they can be altered, or destroyed. Nevertheless, studies of comets and meteorites generally find that ices at least partly retained their interstellar medium (ISM) composition before being accreted onto these minor bodies. Here we model this process through hydrodynamical simulations with VSI-driven turbulence in the outer protoplanetary disk. We use the PLUTO code in a 2.5 D global accretion setup and include Lagrangian dust particles of 0.1 and 1 mm sizes. In a post-processing step, we use the RADMC3D code to generate the local UV radiation field to assess the level of ice processing of pebbles. We find that a small fraction ($\sim$17$\%$) of 100 $\mu$m size particles are frequently lifted up to $Z/R=0.2$ which can result in the loss of their pristine composition as their residence time in this layer allows for effective CO and water photodissociation. The larger 1 mm size particles remain UV-shielded in the disk midplane throughout the dynamical evolution of the disk. Our results indicate that the assembly of icy bodies via the accretion of drifting mm-size icy pebbles can explain the presence of pristine ice from the ISM, even in VSI-turbulent disks. Nevertheless, particles $\leq$ 100 $\mu$m experience efficient UV processing and may mix with unaltered icy pebbles, resulting in a less ISM-like composition in the midplane., Comment: Accepted to A&A
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- 2024
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9. LightSC: The Making of a Usable Security Classification Tool for DevSecOps
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Shrestha, Manish, Johansen, Christian, and Johansen, Johanna
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Computer Science - Cryptography and Security ,Computer Science - Human-Computer Interaction ,Computer Science - Software Engineering - Abstract
DevSecOps, as the extension of DevOps with security training and tools, has become a popular way of developing modern software, especially in the Internet of Things arena, due to its focus on rapid development, with short release cycles, involving the user/client very closely. Security classification methods, on the other hand, are heavy and slow processes that require high expertise in security, the same as in other similar areas such as risk analysis or certification. As such, security classification methods are hardly compatible with the DevSecOps culture, which to the contrary, has moved away from the traditional style of penetration testing done only when the software product is in the final stages or already deployed. In this work, we first propose five principles for a security classification to be \emph{DevOps-ready}, two of which will be the focus for the rest of the paper, namely to be tool-based and easy to use for non-security experts, such as ordinary developers or system architects. We then exemplify how one can make a security classification methodology DevOps-ready. We do this through an interaction design process, where we create and evaluate the usability of a tool implementing the chosen methodology. Since such work seems to be new within the usable security community, and even more so in the software development (DevOps) community, we extract from our process a general, three-steps `recipe' that others can follow when making their own security methodologies DevOps-ready. The tool that we build is in itself a contribution of this process, as it can be independently used, extended, and/or integrated by developer teams into their DevSecOps tool-chains. Our tool is perceived (by the test subjects) as most useful in the design phase, but also during the testing phase where the security class would be one of the metrics used to evaluate the quality of their software., Comment: 29 pages of which 7 are appendix with figures
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- 2024
10. Next generation thiazolyl ketone inhibitors of cytosolic phospholipase A2 α for targeted cancer therapy.
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Ashcroft, Felicity, Bourboula, Asimina, Mahammad, Nur, Barbayianni, Efrosini, Feuerherm, Astrid, Nguyen, Thanh, Hayashi, Daiki, Kokotou, Maroula, Alevizopoulos, Konstantinos, Dennis, Edward, Kokotos, George, and Johansen, Berit
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Humans ,Group IV Phospholipases A2 ,Cell Line ,Tumor ,Ketones ,Reactive Oxygen Species ,Thiazoles ,Antineoplastic Agents ,Cell Survival ,Oxidative Stress ,Neoplasms ,Enzyme Inhibitors - Abstract
Eicosanoids are key players in inflammatory diseases and cancer. Targeting their production by inhibiting Group IVA cytosolic phospholipase A2 (cPLA2α) offers a promising approach for cancer therapy. In this study, we synthesize a second generation of thiazolyl ketone inhibitors of cPLA2α starting with compound GK470 (AVX235) and test their in vitro and cellular activities. We identify a more potent and selective lead molecule, GK420 (AVX420), which we test in parallel with AVX235 and a structurally unrelated compound, AVX002 for inhibition of cell viability across a panel of cancer cell lines. From this, we show that activity of polycomb group repressive complex 2 is a key molecular determinant of sensitivity to cPLA2α inhibition, while resistance depends on antioxidant response pathways. Consistent with these results, we show that elevated intracellular reactive oxygen species and activating transcription factor 4 target gene expression precede cell death in AVX420-sensitive T-cell acute lymphoblastic leukemia cells. Our findings imply cPLA2α may support cancer by mitigating oxidative stress and inhibiting tumor suppressor expression and suggest that AVX420 has potential for treating acute leukemias and other cancers that are susceptible to oxidative cell death.
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- 2025
11. Redesigning the ensemble Kalman filter with a dedicated model of epistemic uncertainty
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Kimchaiwong, Chatchuea, Houssineau, Jeremie, and Johansen, Adam M.
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Statistics - Methodology ,Computer Science - Artificial Intelligence ,62F15, 65C35 - Abstract
The problem of incorporating information from observations received serially in time is widespread in the field of uncertainty quantification. Within a probabilistic framework, such problems can be addressed using standard filtering techniques. However, in many real-world problems, some (or all) of the uncertainty is epistemic, arising from a lack of knowledge, and is difficult to model probabilistically. This paper introduces a possibilistic ensemble Kalman filter designed for this setting and characterizes some of its properties. Using possibility theory to describe epistemic uncertainty is appealing from a philosophical perspective, and it is easy to justify certain heuristics often employed in standard ensemble Kalman filters as principled approaches to capturing uncertainty within it. The possibilistic approach motivates a robust mechanism for characterizing uncertainty which shows good performance with small sample sizes, and can outperform standard ensemble Kalman filters at given sample size, even when dealing with genuinely aleatoric uncertainty.
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- 2024
12. Comment on 'Did the terrestrial planets of the Solar System form by pebble accretion?'
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Johansen, Anders, Olson, Peter, and Sharp, Zachary
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Astrophysics - Earth and Planetary Astrophysics - Abstract
Morbidelli, Kleine & Nimmo (2024) (MKN) recently published a critical analysis on whether the terrestrial planets in the Solar System formed by rapid pebble accretion or by the classical route of multiple giant impacts between planetary embryos after the dissipation of the protoplanetary disc. They arrive at the conclusion that the terrestrial planets did not form by pebble accretion. Although we welcome debate on this topic, we want to emphasize here several points that we disagree on. We will not address in detail every claim made in MKN, but rather stick to four main points. Our conclusion is that pebble accretion remains a viable mechanism to drive significant growth of protoplanets in the protoplanetary disc, with as much as 70% of Earth formed by pebble accretion. This rapid growth phase must nevertheless have been followed by an extended period of collisional growth after the end of the protoplanetary disc phase, likely culminating with the moon-forming giant impact. We emphasize here an important recent result from Olson & Sharp (2023), namely that significant growth by pebble accretion can be reconciled with the Hf-W decay system even for a canonical moon-forming giant impact with a Mars-mass protoplanet and a low equilibration efficiency - a more massive impactor, as proposed in Johansen et al. (2023), is not necessary. Given that terrestrial planet formation naturally involves both pebble accretion and a combination of small and large impactors, this challenges the very notion of making an either/or distinction between the classical collision model and the pebble accretion model., Comment: Comment on arXiv:2411.09271 (slight correction to abstract here), 6 pages, 1 figure, comments and questions welcome
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- 2024
13. Verifying Machine Unlearning with Explainable AI
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Vidal, Àlex Pujol, Johansen, Anders S., Jahromi, Mohammad N. S., Escalera, Sergio, Nasrollahi, Kamal, and Moeslund, Thomas B.
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Computer Science - Machine Learning ,Computer Science - Artificial Intelligence - Abstract
We investigate the effectiveness of Explainable AI (XAI) in verifying Machine Unlearning (MU) within the context of harbor front monitoring, focusing on data privacy and regulatory compliance. With the increasing need to adhere to privacy legislation such as the General Data Protection Regulation (GDPR), traditional methods of retraining ML models for data deletions prove impractical due to their complexity and resource demands. MU offers a solution by enabling models to selectively forget specific learned patterns without full retraining. We explore various removal techniques, including data relabeling, and model perturbation. Then, we leverage attribution-based XAI to discuss the effects of unlearning on model performance. Our proof-of-concept introduces feature importance as an innovative verification step for MU, expanding beyond traditional metrics and demonstrating techniques' ability to reduce reliance on undesired patterns. Additionally, we propose two novel XAI-based metrics, Heatmap Coverage (HC) and Attention Shift (AS), to evaluate the effectiveness of these methods. This approach not only highlights how XAI can complement MU by providing effective verification, but also sets the stage for future research to enhance their joint integration., Comment: ICPRW2024
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- 2024
14. Comparative Analysis of Audio Feature Extraction for Real-Time Talking Portrait Synthesis
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Salehi, Pegah, Sheshkal, Sajad Amouei, Thambawita, Vajira, Gautam, Sushant, Sabet, Saeed S., Johansen, Dag, Riegler, Michael A., and Halvorsen, Pål
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Computer Science - Sound ,Computer Science - Artificial Intelligence ,Computer Science - Human-Computer Interaction ,Electrical Engineering and Systems Science - Audio and Speech Processing ,68T45, 68T07, 68T01 - Abstract
This paper examines the integration of real-time talking-head generation for interviewer training, focusing on overcoming challenges in Audio Feature Extraction (AFE), which often introduces latency and limits responsiveness in real-time applications. To address these issues, we propose and implement a fully integrated system that replaces conventional AFE models with Open AI's Whisper, leveraging its encoder to optimize processing and improve overall system efficiency. Our evaluation of two open-source real-time models across three different datasets shows that Whisper not only accelerates processing but also improves specific aspects of rendering quality, resulting in more realistic and responsive talking-head interactions. These advancements make the system a more effective tool for immersive, interactive training applications, expanding the potential of AI-driven avatars in interviewer training., Comment: 16 pages, 6 figures, 3 tables. submitted to MDPI journal in as Big Data and Cognitive Computing
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- 2024
15. Qutrit Toric Code and Parafermions in Trapped Ions
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Iqbal, Mohsin, Lyons, Anasuya, Lo, Chiu Fan Bowen, Tantivasadakarn, Nathanan, Dreiling, Joan, Foltz, Cameron, Gatterman, Thomas M., Gresh, Dan, Hewitt, Nathan, Holliman, Craig A., Johansen, Jacob, Neyenhuis, Brian, Matsuoka, Yohei, Mills, Michael, Moses, Steven A., Siegfried, Peter, Vishwanath, Ashvin, Verresen, Ruben, and Dreyer, Henrik
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Quantum Physics ,Condensed Matter - Strongly Correlated Electrons - Abstract
The development of programmable quantum devices can be measured by the complexity of manybody states that they are able to prepare. Among the most significant are topologically ordered states of matter, which enable robust quantum information storage and processing. While topological orders are more readily accessible with qudits, experimental realisations have thus far been limited to lattice models of qubits. Here, we prepare a ground state of the Z3 toric code state on 24 qutrits in a trapped ion quantum processor with fidelity per qutrit exceeding 96.5(3)%. We manipulate two types of defects which go beyond the conventional qubit toric code: a parafermion, and its bound state which is related to charge conjugation symmetry. We further demonstrate defect fusion and the transfer of entanglement between anyons and defects, which we use to control topological qutrits. Our work opens up the space of long-range entangled states with qudit degrees of freedom for use in quantum simulation and universal error-correcting codes., Comment: 8+20 pages, 15 figures
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- 2024
16. Large Interferometer For Exoplanets (LIFE). XIV. Finding terrestrial protoplanets in the galactic neighborhood
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Cesario, Lorenzo, Lichtenberg, Tim, Alei, Eleonora, Carrión-González, Óscar, Dannert, Felix A., Defrère, Denis, Ertel, Steve, Fortier, Andrea, Muñoz, A. García, Glauser, Adrian M., Hansen, Jonah T., Helled, Ravit, Huber, Philipp A., Ireland, Michael J., Kammerer, Jens, Laugier, Romain, Lillo-Box, Jorge, Menti, Franziska, Meyer, Michael R., Noack, Lena, Quanz, Sascha P., Quirrenbach, Andreas, Rugheimer, Sarah, van der Tak, Floris, Wang, Haiyang S., Anger, Marius, Balsalobre-Ruza, Olga, Bhattarai, Surendra, Braam, Marrick, Castro-González, Amadeo, Cockell, Charles S., Constantinou, Tereza, Cugno, Gabriele, Davoult, Jeanne, Güdel, Manuel, Hernitschek, Nina, Hinkley, Sasha, Itoh, Satoshi, Janson, Markus, Johansen, Anders, Jones, Hugh R. A., Kane, Stephen R., van Kempen, Tim A., Kislyakova, Kristina G., Korth, Judith, Kovacevic, Andjelka B., Kraus, Stefan, Kuiper, Rolf, Mathew, Joice, Matsuo, Taro, Miguel, Yamila, Min, Michiel, Navarro, Ramon, Ramirez, Ramses M., Rauer, Heike, Ricketti, Berke Vow, Romagnolo, Amedeo, Schlecker, Martin, Sneed, Evan L., Squicciarini, Vito, Stassun, Keivan G., Tamura, Motohide, Viudez-Moreiras, Daniel, Wordsworth, Robin D., and Collaboration, the LIFE
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Instrumentation and Methods for Astrophysics ,Physics - Geophysics - Abstract
The increased brightness temperature of young rocky protoplanets during their magma ocean epoch makes them potentially amenable to atmospheric characterization to distances from the solar system far greater than thermally equilibrated terrestrial exoplanets, offering observational opportunities for unique insights into the origin of secondary atmospheres and the near surface conditions of prebiotic environments. The Large Interferometer For Exoplanets (LIFE) mission will employ a space-based mid-infrared nulling interferometer to directly measure the thermal emission of terrestrial exoplanets. Here, we seek to assess the capabilities of various instrumental design choices of the LIFE mission concept for the detection of cooling protoplanets with transient high-temperature magma ocean atmospheres, in young stellar associations in particular. Using the LIFE mission instrument simulator (LIFEsim) we assess how specific instrumental parameters and design choices, such as wavelength coverage, aperture diameter, and photon throughput, facilitate or disadvantage the detection of protoplanets. We focus on the observational sensitivities of distance to the observed planetary system, protoplanet brightness temperature using a blackbody assumption, and orbital distance of the potential protoplanets around both G- and M-dwarf stars. Our simulations suggest that LIFE will be able to detect (S/N $\geq$ 7) hot protoplanets in young stellar associations up to distances of $\approx$100 pc from the solar system for reasonable integration times (up to $\sim$hours). Detection of an Earth-sized protoplanet orbiting a solar-sized host star at 1 AU requires less than 30 minutes of integration time. M-dwarfs generally need shorter integration times. The contribution from wavelength regions $<$6 $\mu$m is important for decreasing the detection threshold and discriminating emission temperatures., Comment: 18 pages, 19 figures; accepted for publication in A&A
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- 2024
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17. Thousands of planetesimals: Simulating the streaming Instability in very large computational domains
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Schäfer, Urs, Johansen, Anders, Haugbølle, Troels, and Nordlund, Åke
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Astrophysics - Earth and Planetary Astrophysics - Abstract
The streaming instability is a mechanism whereby pebble-sized particles in protoplanetary discs spontaneously come together in dense filaments, which collapse gravitationally to form planetesimals upon reaching the Roche density. The extent of the filaments along the orbital direction is nevertheless poorly characterised, due to a focus in the literature on small simulation domains where the behaviour of the streaming instability on large scales cannot be determined. We present here computer simulations of the streaming instability in boxes with side lengths up to 6.4 scale heights in the plane. This is 32 times larger than typically considered simulation domains and nearly a factor 1,000 times the volume. We show that the azimuthal extent of filaments in the non-linear state of the streaming instability is limited to approximately one gas scale height. The streaming instability will therefore not transform the pebble density field into axisymmetric rings; rather the non-linear state of the streaming instability appears as a complex structure of loosely connected filaments. Including the self-gravity of the pebbles, our simulations form up to 4,000 planetesimals. This allows us to probe the high-mass end of the initial mass function of planetesimals with much higher statistical confidence than previously. We find that this end is well-described by a steep exponential tapering. Since the resolution of our simulations is moderate -- a necessary trade-off given the large domains -- the mass distribution is incomplete at the low-mass end. When putting comparatively less weight on the numbers at low masses, at intermediate masses we nevertheless reproduce the power-law shape of the distribution established in previous studies., Comment: 15 pages, 14 figures, 2 tables; accepted for publication in A&A
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- 2024
18. Solving Fredholm Integral Equations of the Second Kind via Wasserstein Gradient Flows
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Crucinio, Francesca R. and Johansen, Adam M.
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Statistics - Computation ,Mathematics - Numerical Analysis ,Mathematics - Optimization and Control ,Statistics - Methodology ,65Rxx, 65C35, 65K10, 45B05 - Abstract
Motivated by a recent method for approximate solution of Fredholm equations of the first kind, we develop a corresponding method for a class of Fredholm equations of the \emph{second kind}. In particular, we consider the class of equations for which the solution is a probability measure. The approach centres around specifying a functional whose gradient flow admits a minimizer corresponding to a regularized version of the solution of the underlying equation and using a mean-field particle system to approximately simulate that flow. Theoretical support for the method is presented, along with some illustrative numerical results.
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- 2024
19. Self-oxidation of the atmospheres of rocky planets with implications for the origin of life
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Johansen, Anders, Camprubi, Eloi, van Kooten, Elishevah, and Hoeijmakers, Jens
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Astrophysics - Earth and Planetary Astrophysics - Abstract
Rocky planets may acquire a primordial atmosphere by outgassing of volatiles from their magma ocean. The distribution of O between H$_2$O, CO and CO$_2$ in chemical equilibrium subsequently changes significantly with decreasing temperature. We explore here two chemical models: one where CH$_4$ and NH$_3$ are assumed to be irrevocably destroyed by photolysis, and one where these molecules persist. In the first case, we show that CO cannot co-exist with H$_2$O, since CO oxidizes at low temperatures to form CO$_2$ and H$_2$. In both cases, H escapes from the thermosphere within a few ten million years by absorption of stellar XUV radiation. This escape drives an atmospheric self-oxidation process whereby rocky planet atmospheres become dominated by CO$_2$ and H$_2$O, regardless of their initial oxidation state at outgassing. HCN is considered a potential precursor of prebiotic compounds and RNA. Our oxidizing atmospheres are inefficient at producing HCN by lightning. Instead, we demonstrate that lightning-produced NO, which dissolves as nitrate in the oceans, and interplanetary dust particles may be the main sources of fixed nitrogen to emerging biospheres. Our results highlight the need for origin-of-life scenarios where the first metabolism fixes its C from CO$_2$, rather than from HCN and CO., Comment: Accepted for publication in Astrobiology
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- 2024
20. Evolution of gas envelopes and outgassed atmospheres of rocky planets formed via pebble accretion
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Tomberg, Piia Maria and Johansen, Anders
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Astrophysics - Earth and Planetary Astrophysics - Abstract
We present here results of numerical simulations of the formation and early evolution of rocky planets through pebble accretion, with an with an emphasis on hydrogen envelope longevity and the composition of the outgassed atmosphere. We model planets with a range in mass from 0.1 to 5 Earth masses that orbit between 0.7 and 1.7 AU. The composition of the outgassed atmosphere is calculated with the partial pressure of free oxygen fit to geophysical models of magma ocean self-oxidation. XUV radiation powered photoevaporation is considered as the main driver of atmospheric escape. We model planets that remain below the pebble isolation mass and hence accrete tenuous envelopes only. We consider slow, medium or fast initial stellar rotation for the temporal evolution of the XUV flux. The loss of the envelope is a key event that allows the magma ocean to crystallise and outgas its bulk volatiles. The atmospheric composition of the majority of our simulated planets is dominated by CO$_2$. Our planets accrete a total of 11.6 Earth oceans of water, the majority of which enters the core. The hydrospheres of planets lighter than the Earth reach several times the mass of the Earth's modern oceans, while the hydrospheres of planets ranging from 1 to 3.5 Earth masses are comparable to those of our planet. However, planets of 4-5 Earth masses have smaller hydrospheres due to trapping of volatiles in their massive mantles. Overall, our simulations demonstrate that hydrogen envelopes are easily lost from rocky planets and that this envelope loss triggers the most primordial partitioning of volatiles between the solid mantle and the atmosphere., Comment: Accepted for Astronomy & Astrophysics
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- 2024
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21. Deep Brain Ultrasound Ablation Thermal Dose Modeling with in Vivo Experimental Validation
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Zhao, Zhanyue, Szewczyk, Benjamin, Tarasek, Matthew, Bales, Charles, Wang, Yang, Liu, Ming, Jiang, Yiwei, Bhushan, Chitresh, Fiveland, Eric, Campwala, Zahabiya, Trowbridge, Rachel, Johansen, Phillip M., Olmsted, Zachary, Ghoshal, Goutam, Heffter, Tamas, Gandomi, Katie, Tavakkolmoghaddam, Farid, Nycz, Christopher, Jeannotte, Erin, Mane, Shweta, Nalwalk, Julia, Burdette, E. Clif, Qian, Jiang, Yeo, Desmond, Pilitsis, Julie, and Fischer, Gregory S.
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Physics - Medical Physics ,Computer Science - Robotics - Abstract
Intracorporeal needle-based therapeutic ultrasound (NBTU) is a minimally invasive option for intervening in malignant brain tumors, commonly used in thermal ablation procedures. This technique is suitable for both primary and metastatic cancers, utilizing a high-frequency alternating electric field (up to 10 MHz) to excite a piezoelectric transducer. The resulting rapid deformation of the transducer produces an acoustic wave that propagates through tissue, leading to localized high-temperature heating at the target tumor site and inducing rapid cell death. To optimize the design of NBTU transducers for thermal dose delivery during treatment, numerical modeling of the acoustic pressure field generated by the deforming piezoelectric transducer is frequently employed. The bioheat transfer process generated by the input pressure field is used to track the thermal propagation of the applicator over time. Magnetic resonance thermal imaging (MRTI) can be used to experimentally validate these models. Validation results using MRTI demonstrated the feasibility of this model, showing a consistent thermal propagation pattern. However, a thermal damage isodose map is more advantageous for evaluating therapeutic efficacy. To achieve a more accurate simulation based on the actual brain tissue environment, a new finite element method (FEM) simulation with enhanced damage evaluation capabilities was conducted. The results showed that the highest temperature and ablated volume differed between experimental and simulation results by 2.1884{\deg}C (3.71%) and 0.0631 cm$^3$ (5.74%), respectively. The lowest Pearson correlation coefficient (PCC) for peak temperature was 0.7117, and the lowest Dice coefficient for the ablated area was 0.7021, indicating a good agreement in accuracy between simulation and experiment., Comment: 9 pages, 9 figures, 7 tables
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- 2024
22. Reactant Discovery with an Ab Initio Nanoreactor: Exploration of Astrophysical N-Heterocycle Precursors and Formation Pathways.
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Johansen, Sommer, Park, Heejune, Wang, Lee-Ping, and Crabtree, Kyle
- Abstract
The incorporation of nitrogen atoms into cyclic compounds is essential for terrestrial life; nitrogen-containing (N-)heterocycles make up DNA and RNA nucleobases, several amino acids, B vitamins, porphyrins, and other components of biomolecules. The discovery of these molecules on meteorites with non-terrestrial isotopic abundances supports the hypothesis of exogenous delivery of prebiotic material to early Earth; however, there has been no detection of these species in interstellar environments, indicating that there is a need for greater knowledge of their astrochemical formation and destruction pathways. Here, we present results of simulations of gas-phase pyrrole and pyridine formation from an ab initio nanoreactor, a first-principles molecular dynamics simulation method that accelerates reaction discovery by applying non-equilibrium forces that are agnostic to individual reaction coordinates. Using the nanoreactor in a retrosynthetic mode, starting with the N-heterocycle of interest and a radical leaving group, then considering the discovered reaction pathways in reverse, a rich landscape of N-heterocycle-forming reactivity can be found. Several of these reaction pathways, when mapped to their corresponding minimum energy paths, correspond to novel barrierless formation pathways for pyridine and pyrrole, starting from both detected and hypothesized astrochemical precursors. This study demonstrates how first-principles reaction discovery can build mechanistic knowledge in astrochemical environments as well as in early Earth models such as Titans atmosphere where N-heterocycles have been tentatively detected.
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- 2024
23. Time-resolved measurement of neutron energy isotropy in a sheared-flow-stabilized Z pinch
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Ryan, R. A., Tsai, P. E., Johansen, A. R., Youmans, A., Higginson, D. P., Mitrani, J. M., Adams, C. S., Sutherland, D. A., Levitt, B., and Shumlak, U.
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Physics - Plasma Physics ,Nuclear Experiment - Abstract
Previous measurements of neutron energy using fast plastic scintillators while operating the Fusion Z Pinch Experiment (FuZE) constrained the energy of any yield-producing deuteron beams to less than $4.65 keV$. FuZE has since been operated at increasingly higher input power, resulting in increased plasma current and larger fusion neutron yields. A detailed experimental study of the neutron energy isotropy in these regimes applies more stringent limits to possible contributions from beam-target fusion. The FuZE device operated at $-25~kV$ charge voltage has resulted in average plasma currents of $370~kA$ and D-D fusion neutron yields of $4\times10^7$ neutrons per discharge. Measurements of the neutron energy isotropy under these operating conditions demonstrates the energy of deuteron beams is less than $7.4 \pm 5.6^\mathrm{(stat)} \pm 3.7^\mathrm{(syst)}~keV$. Characterization of the detector response has reduced the number of free parameters in the fit of the neutron energy distribution, improving the confidence in the forward-fit method. Gamma backgrounds have been measured and the impact of these contributions on the isotropy results have been studied. Additionally, a time dependent measurement of the isotropy has been resolved for the first time, indicating increases to possible deuteron beam energies at late times. This suggests the possible growth of $m$=0 instabilities at the end of the main radiation event but confirms that the majority of the neutron production exhibits isotropy consistent with thermonuclear origin., Comment: 16 pages, 11 figures, submitted to Journal of Nuclear Fusion
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- 2024
24. Fast convergence of the Expectation Maximization algorithm under a logarithmic Sobolev inequality
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Caprio, Rocco and Johansen, Adam M
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Statistics - Machine Learning ,Computer Science - Machine Learning ,Mathematics - Optimization and Control ,Mathematics - Statistics Theory ,Statistics - Computation - Abstract
By utilizing recently developed tools for constructing gradient flows on Wasserstein spaces, we extend an analysis technique commonly employed to understand alternating minimization algorithms on Euclidean space to the Expectation Maximization (EM) algorithm via its representation as coordinate-wise minimization on the product of a Euclidean space and a space of probability distributions due to Neal and Hinton (1998). In so doing we obtain finite sample error bounds and exponential convergence of the EM algorithm under a natural generalisation of a log-Sobolev inequality. We further demonstrate that the analysis technique is sufficiently flexible to allow also the analysis of several variants of the EM algorithm.
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- 2024
25. Particle Semi-Implicit Variational Inference
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Lim, Jen Ning and Johansen, Adam M.
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Statistics - Machine Learning ,Computer Science - Machine Learning - Abstract
Semi-implicit variational inference (SIVI) enriches the expressiveness of variational families by utilizing a kernel and a mixing distribution to hierarchically define the variational distribution. Existing SIVI methods parameterize the mixing distribution using implicit distributions, leading to intractable variational densities. As a result, directly maximizing the evidence lower bound (ELBO) is not possible, so they resort to one of the following: optimizing bounds on the ELBO, employing costly inner-loop Markov chain Monte Carlo runs, or solving minimax objectives. In this paper, we propose a novel method for SIVI called Particle Variational Inference (PVI) which employs empirical measures to approximate the optimal mixing distributions characterized as the minimizer of a free energy functional. PVI arises naturally as a particle approximation of a Euclidean--Wasserstein gradient flow and, unlike prior works, it directly optimizes the ELBO whilst making no parametric assumption about the mixing distribution. Our empirical results demonstrate that PVI performs favourably compared to other SIVI methods across various tasks. Moreover, we provide a theoretical analysis of the behaviour of the gradient flow of a related free energy functional: establishing the existence and uniqueness of solutions as well as propagation of chaos results., Comment: NeurIPS 2024 Camera ready
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- 2024
26. Genealogical processes of non-neutral population models under rapid mutation
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Koskela, Jere, Jenkins, Paul A., Johansen, Adam M., and Spano, Dario
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Mathematics - Probability ,Quantitative Biology - Populations and Evolution ,Statistics - Computation ,60J90, 65C35, 92D15 - Abstract
We show that genealogical trees arising from a broad class of non-neutral models of population evolution converge to the Kingman coalescent under a suitable rescaling of time. As well as non-neutral biological evolution, our results apply to genetic algorithms encompassing the prominent class of sequential Monte Carlo (SMC) methods. The time rescaling we need differs slightly from that used in classical results for convergence to the Kingman coalescent, which has implications for the performance of different resampling schemes in SMC algorithms. In addition, our work substantially simplifies earlier proofs of convergence to the Kingman coalescent, and corrects an error common to several earlier results.
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- 2024
27. The PLATO Mission
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Rauer, Heike, Aerts, Conny, Cabrera, Juan, Deleuil, Magali, Erikson, Anders, Gizon, Laurent, Goupil, Mariejo, Heras, Ana, Lorenzo-Alvarez, Jose, Marliani, Filippo, Martin-Garcia, César, Mas-Hesse, J. Miguel, O'Rourke, Laurence, Osborn, Hugh, Pagano, Isabella, Piotto, Giampaolo, Pollacco, Don, Ragazzoni, Roberto, Ramsay, Gavin, Udry, Stéphane, Appourchaux, Thierry, Benz, Willy, Brandeker, Alexis, Güdel, Manuel, Janot-Pacheco, Eduardo, Kabath, Petr, Kjeldsen, Hans, Min, Michiel, Santos, Nuno, Smith, Alan, Suarez, Juan-Carlos, Werner, Stephanie C., Aboudan, Alessio, Abreu, Manuel, a, Lorena Acu, Adams, Moritz, Adibekyan, Vardan, Affer, Laura, Agneray, François, Agnor, Craig, Børsen-Koch, Victor Aguirre, Ahmed, Saad, Aigrain, Suzanne, Al-Bahlawan, Ashraf, Gil, M de los Angeles Alcacera, Alei, Eleonora, Alencar, Silvia, Alexander, Richard, Alfonso-Garzón, Julia, Alibert, Yann, Prieto, Carlos Allende, Almeida, Leonardo, Sobrino, Roi Alonso, Altavilla, Giuseppe, Althaus, Christian, Trujillo, Luis Alonso Alvarez, Amarsi, Anish, Eiff, Matthias Ammler-von, Amôres, Eduardo, Andrade, Laerte, Antoniadis-Karnavas, Alexandros, António, Carlos, del Moral, Beatriz Aparicio, Appolloni, Matteo, Arena, Claudio, Armstrong, David, Aliaga, Jose Aroca, Asplund, Martin, Audenaert, Jeroen, Auricchio, Natalia, Avelino, Pedro, Baeke, Ann, Baillié, Kevin, Balado, Ana, Balagueró, Pau Ballber, Balestra, Andrea, Ball, Warrick, Ballans, Herve, Ballot, Jerome, Barban, Caroline, Barbary, Gaële, Barbieri, Mauro, Forteza, Sebasti Barceló, Barker, Adrian, Barklem, Paul, Barnes, Sydney, Navascues, David Barrado, Barragan, Oscar, Baruteau, Clément, Basu, Sarbani, Baudin, Frederic, Baumeister, Philipp, Bayliss, Daniel, Bazot, Michael, Beck, Paul G., Bedding, Tim, Belkacem, Kevin, Bellinger, Earl, Benatti, Serena, Benomar, Othman, Bérard, Diane, Bergemann, Maria, Bergomi, Maria, Bernardo, Pierre, Biazzo, Katia, Bignamini, Andrea, Bigot, Lionel, Billot, Nicolas, Binet, Martin, Biondi, David, Biondi, Federico, Birch, Aaron C., Bitsch, Bertram, Ceballos, Paz Victoria Bluhm, Bódi, Attila, Bognár, Zsófia, Boisse, Isabelle, Bolmont, Emeline, Bonanno, Alfio, Bonavita, Mariangela, Bonfanti, Andrea, Bonfils, Xavier, Bonito, Rosaria, Bonomo, Aldo Stefano, Börner, Anko, Saikia, Sudeshna Boro, Martín, Elisa Borreguero, Borsa, Francesco, Borsato, Luca, Bossini, Diego, Bouchy, Francois, Boué, Gwenaël, Boufleur, Rodrigo, Boumier, Patrick, Bourrier, Vincent, Bowman, Dominic M., Bozzo, Enrico, Bradley, Louisa, Bray, John, Bressan, Alessandro, Breton, Sylvain, Brienza, Daniele, Brito, Ana, Brogi, Matteo, Brown, Beverly, Brown, David J. A., Brun, Allan Sacha, Bruno, Giovanni, Bruns, Michael, Buchhave, Lars A., Bugnet, Lisa, Buldgen, Gaël, Burgess, Patrick, Busatta, Andrea, Busso, Giorgia, Buzasi, Derek, Caballero, José A., Cabral, Alexandre, Gomez, Juan-Francisco Cabrero, Calderone, Flavia, Cameron, Robert, Cameron, Andrew, Campante, Tiago, Gestal, Néstor Campos, Martins, Bruno Leonardo Canto, Cara, Christophe, Carone, Ludmila, Carrasco, Josep Manel, Casagrande, Luca, Casewell, Sarah L., Cassisi, Santi, Castellani, Marco, Castro, Matthieu, Catala, Claude, Fernández, Irene Catalán, Catelan, Márcio, Cegla, Heather, Cerruti, Chiara, Cessa, Virginie, Chadid, Merieme, Chaplin, William, Charpinet, Stephane, Chiappini, Cristina, Chiarucci, Simone, Chiavassa, Andrea, Chinellato, Simonetta, Chirulli, Giovanni, Christensen-Dalsgaard, Jørgen, Church, Ross, Claret, Antonio, Clarke, Cathie, Claudi, Riccardo, Clermont, Lionel, Coelho, Hugo, Coelho, Joao, Cogato, Fabrizio, Colomé, Josep, Condamin, Mathieu, García, Fernando Conde, Conseil, Simon, Corbard, Thierry, Correia, Alexandre C. M., Corsaro, Enrico, Cosentino, Rosario, Costes, Jean, Cottinelli, Andrea, Covone, Giovanni, Creevey, Orlagh L., Crida, Aurelien, Csizmadia, Szilard, Cunha, Margarida, Curry, Patrick, da Costa, Jefferson, da Silva, Francys, Dalal, Shweta, Damasso, Mario, Damiani, Cilia, Damiani, Francesco, Chagas, Maria Liduina das, Davies, Melvyn, Davies, Guy, Davies, Ben, Davison, Gary, de Almeida, Leandro, de Angeli, Francesca, de Barros, Susana Cristina Cabral, Leão, Izan de Castro, de Freitas, Daniel Brito, de Freitas, Marcia Cristina, De Martino, Domitilla, de Medeiros, José Renan, de Paula, Luiz Alberto, Gómez, Álvaro de Pedraza, de Plaa, Jelle, De Ridder, Joris, Deal, Morgan, Decin, Leen, Deeg, Hans, Innocenti, Scilla Degl, Deheuvels, Sebastien, del Burgo, Carlos, Del Sordo, Fabio, Delgado-Mena, Elisa, Demangeon, Olivier, Denk, Tilmann, Derekas, Aliz, Desert, Jean-Michel, Desidera, Silvano, Dexet, Marc, Di Criscienzo, Marcella, Di Giorgio, Anna Maria, Di Mauro, Maria Pia, Rial, Federico Jose Diaz, Díaz-García, José-Javier, Dima, Marco, Dinuzzi, Giacomo, Dionatos, Odysseas, Distefano, Elisa, Nascimento Jr., Jose-Dias do, Domingo, Albert, D'Orazi, Valentina, Dorn, Caroline, Doyle, Lauren, Duarte, Elena, Ducellier, Florent, Dumaye, Luc, Dumusque, Xavier, Dupret, Marc-Antoine, Eggenberger, Patrick, Ehrenreich, David, Eigmüller, Philipp, Eising, Johannes, Emilio, Marcelo, Eriksson, Kjell, Ermocida, Marco, Giribaldi, Riano Isidoro Escate, Eschen, Yoshi, ez, Lucía Espinosa Yá, Estrela, In s, Evans, Dafydd Wyn, Fabbian, Damian, Fabrizio, Michele, Faria, João Pedro, Farina, Maria, Farinato, Jacopo, Feliz, Dax, Feltzing, Sofia, Fenouillet, Thomas, Fernández, Miguel, Ferrari, Lorenza, Ferraz-Mello, Sylvio, Fialho, Fabio, Fienga, Agnes, Figueira, Pedro, Fiori, Laura, Flaccomio, Ettore, Focardi, Mauro, Foley, Steve, Fontignie, Jean, Ford, Dominic, Fornazier, Karin, Forveille, Thierry, Fossati, Luca, Franca, Rodrigo de Marca, da Silva, Lucas Franco, Frasca, Antonio, Fridlund, Malcolm, Furlan, Marco, Gabler, Sarah-Maria, Gaido, Marco, Gallagher, Andrew, Sempere, Paloma I. Gallego, Galli, Emanuele, García, Rafael A., Hernández, Antonio García, Munoz, Antonio Garcia, García-Vázquez, Hugo, Haba, Rafael Garrido, Gaulme, Patrick, Gauthier, Nicolas, Gehan, Charlotte, Gent, Matthew, Georgieva, Iskra, Ghigo, Mauro, Giana, Edoardo, Gill, Samuel, Girardi, Leo, Winter, Silvia Giuliatti, Giusi, Giovanni, da Silva, João Gomes, Zazo, Luis Jorge Gómez, Gomez-Lopez, Juan Manuel, Hernández, Jonay Isai González, Murillo, Kevin Gonzalez, Melchor, Alejandro Gonzalo, Gorius, Nicolas, Gouel, Pierre-Vincent, Goulty, Duncan, Granata, Valentina, Grenfell, John Lee, bach, Denis Grie, Grolleau, Emmanuel, Grouffal, Salomé, Grziwa, Sascha, Guarcello, Mario Giuseppe, Gueguen, Lo c, Guenther, Eike Wolf, Guilhem, Terrasa, Guillerot, Lucas, Guillot, Tristan, Guiot, Pierre, Guterman, Pascal, Gutiérrez, Antonio, Gutiérrez-Canales, Fernando, Hagelberg, Janis, Haldemann, Jonas, Hall, Cassandra, Handberg, Rasmus, Harrison, Ian, Harrison, Diana L., Hasiba, Johann, Haswell, Carole A., Hatalova, Petra, Hatzes, Artie, Haywood, Raphaelle, Hébrard, Guillaume, Heckes, Frank, Heiter, Ulrike, Hekker, Saskia, Heller, René, Helling, Christiane, Helminiak, Krzysztof, Hemsley, Simon, Heng, Kevin, Herbst, Konstantin, Hermans, Aline, Hermes, JJ, Torres, Nadia Hidalgo, Hinkel, Natalie, Hobbs, David, Hodgkin, Simon, Hofmann, Karl, Hojjatpanah, Saeed, Houdek, Günter, Huber, Daniel, Huesler, Joseph, Hui-Bon-Hoa, Alain, Huygen, Rik, Huynh, Duc-Dat, Iro, Nicolas, Irwin, Jonathan, Irwin, Mike, Izidoro, André, Jacquinod, Sophie, Jannsen, Nicholas Emborg, Janson, Markus, Jeszenszky, Harald, Jiang, Chen, Mancebo, Antonio José Jimenez, Jofre, Paula, Johansen, Anders, Johnston, Cole, Jones, Geraint, Kallinger, Thomas, Kálmán, Szilárd, Kanitz, Thomas, Karjalainen, Marie, Karjalainen, Raine, Karoff, Christoffer, Kawaler, Steven, Kawata, Daisuke, Keereman, Arnoud, Keiderling, David, Kennedy, Tom, Kenworthy, Matthew, Kerschbaum, Franz, Kidger, Mark, Kiefer, Flavien, Kintziger, Christian, Kislyakova, Kristina, Kiss, László, Klagyivik, Peter, Klahr, Hubert, Klevas, Jonas, Kochukhov, Oleg, Köhler, Ulrich, Kolb, Ulrich, Koncz, Alexander, Korth, Judith, Kostogryz, Nadiia, Kovács, Gábor, Kovács, József, Kozhura, Oleg, Krivova, Natalie, Kucinskas, Arunas, Kuhlemann, Ilyas, Kupka, Friedrich, Laauwen, Wouter, Labiano, Alvaro, Lagarde, Nadege, Laget, Philippe, Laky, Gunter, Lam, Kristine Wai Fun, Lambrechts, Michiel, Lammer, Helmut, Lanza, Antonino Francesco, Lanzafame, Alessandro, Martiz, Mariel Lares, Laskar, Jacques, Latter, Henrik, Lavanant, Tony, Lawrenson, Alastair, Lazzoni, Cecilia, Lebre, Agnes, Lebreton, Yveline, Etangs, Alain Lecavelier des, Lee, Katherine, Leinhardt, Zoe, Leleu, Adrien, Lendl, Monika, Leto, Giuseppe, Levillain, Yves, Libert, Anne-Sophie, Lichtenberg, Tim, Ligi, Roxanne, Lignieres, Francois, Lillo-Box, Jorge, Linsky, Jeffrey, Liu, John Scige, Loidolt, Dominik, Longval, Yuying, Lopes, Ilídio, Lorenzani, Andrea, Ludwig, Hans-Guenter, Lund, Mikkel, Lundkvist, Mia Sloth, Luri, Xavier, Maceroni, Carla, Madden, Sean, Madhusudhan, Nikku, Maggio, Antonio, Magliano, Christian, Magrin, Demetrio, Mahy, Laurent, Maibaum, Olaf, Malac-Allain, LeeRoy, Malapert, Jean-Christophe, Malavolta, Luca, Maldonado, Jesus, Mamonova, Elena, Manchon, Louis, Manjón, Andres, Mann, Andrew, Mantovan, Giacomo, Marafatto, Luca, Marconi, Marcella, Mardling, Rosemary, Marigo, Paola, Marinoni, Silvia, Marques, rico, Marques, Joao Pedro, Marrese, Paola Maria, Marshall, Douglas, Perales, Silvia Martínez, Mary, David, Marzari, Francesco, Masana, Eduard, Mascher, Andrina, Mathis, Stéphane, Mathur, Savita, Vodopivec, Iris Martín, Figueiredo, Ana Carolina Mattiuci, Maxted, Pierre F. L., Mazeh, Tsevi, Mazevet, Stephane, Mazzei, Francesco, McCormac, James, McMillan, Paul, Menou, Lucas, Merle, Thibault, Meru, Farzana, Mesa, Dino, Messina, Sergio, Mészáros, Szabolcs, Meunier, Nadége, Meunier, Jean-Charles, Micela, Giuseppina, Michaelis, Harald, Michel, Eric, Michielsen, Mathias, Michtchenko, Tatiana, Miglio, Andrea, Miguel, Yamila, Milligan, David, Mirouh, Giovanni, Mitchell, Morgan, Moedas, Nuno, Molendini, Francesca, Molnár, László, Mombarg, Joey, Montalban, Josefina, Montalto, Marco, Monteiro, Mário J. P. F. G., Sánchez, Francisco Montoro, Morales, Juan Carlos, Morales-Calderon, Maria, Morbidelli, Alessandro, Mordasini, Christoph, Moreau, Chrystel, Morel, Thierry, Morello, Guiseppe, Morin, Julien, Mortier, Annelies, Mosser, Beno t, Mourard, Denis, Mousis, Olivier, Moutou, Claire, Mowlavi, Nami, Moya, Andrés, Muehlmann, Prisca, Muirhead, Philip, Munari, Matteo, Musella, Ilaria, Mustill, Alexander James, Nardetto, Nicolas, Nardiello, Domenico, Narita, Norio, Nascimbeni, Valerio, Nash, Anna, Neiner, Coralie, Nelson, Richard P., Nettelmann, Nadine, Nicolini, Gianalfredo, Nielsen, Martin, Niemi, Sami-Matias, Noack, Lena, Noels-Grotsch, Arlette, Noll, Anthony, Norazman, Azib, Norton, Andrew J., Nsamba, Benard, Ofir, Aviv, Ogilvie, Gordon, Olander, Terese, Olivetto, Christian, Olofsson, Göran, Ong, Joel, Ortolani, Sergio, Oshagh, Mahmoudreza, Ottacher, Harald, Ottensamer, Roland, Ouazzani, Rhita-Maria, Paardekooper, Sijme-Jan, Pace, Emanuele, Pajas, Miriam, Palacios, Ana, Palandri, Gaelle, Palle, Enric, Paproth, Carsten, Parro, Vanderlei, Parviainen, Hannu, Granado, Javier Pascual, Passegger, Vera Maria, Pastor-Morales, Carmen, Pätzold, Martin, Pedersen, May Gade, Hidalgo, David Pena, Pepe, Francesco, Pereira, Filipe, Persson, Carina M., Pertenais, Martin, Peter, Gisbert, Petit, Antoine C., Petit, Pascal, Pezzuto, Stefania, Pichierri, Gabriele, Pietrinferni, Adriano, Pinheiro, Fernando, Pinsonneault, Marc, Plachy, Emese, Plasson, Philippe, Plez, Bertrand, Poppenhaeger, Katja, Poretti, Ennio, Portaluri, Elisa, Portell, Jordi, de Mello, Gustavo Frederico Porto, Poyatos, Julien, Pozuelos, Francisco J., Moroni, Pier Giorgio Prada, Pricopi, Dumitru, Prisinzano, Loredana, Quade, Matthias, Quirrenbach, Andreas, Reina, Julio Arturo Rabanal, Soares, Maria Cristina Rabello, Raimondo, Gabriella, Rainer, Monica, Rodón, Jose Ramón, Ramón-Ballesta, Alejandro, Zapata, Gonzalo Ramos, Rätz, Stefanie, Rauterberg, Christoph, Redman, Bob, Redmer, Ronald, Reese, Daniel, Regibo, Sara, Reiners, Ansgar, Reinhold, Timo, Renie, Christian, Ribas, Ignasi, Ribeiro, Sergio, Ricciardi, Thiago Pereira, Rice, Ken, Richard, Olivier, Riello, Marco, Rieutord, Michel, Ripepi, Vincenzo, Rixon, Guy, Rockstein, Steve, Ortiz, José Ramón Rodón, Rodríguez, María Teresa Rodrigo, Amor, Alberto Rodríguez, Díaz, Luisa Fernanda Rodríguez, Garcia, Juan Pablo Rodriguez, Rodriguez-Gomez, Julio, Roehlly, Yannick, Roig, Fernando, Rojas-Ayala, Bárbara, Rolf, Tobias, Rørsted, Jakob Lysgaard, Rosado, Hugo, Rosotti, Giovanni, Roth, Olivier, Roth, Markus, Rousseau, Alex, Roxburgh, Ian, Roy, Fabrice, Royer, Pierre, Ruane, Kirk, Mastropasqua, Sergio Rufini, de Galarreta, Claudia Ruiz, Russi, Andrea, Saar, Steven, Saillenfest, Melaine, Salaris, Maurizio, Salmon, Sebastien, Saltas, Ippocratis, Samadi, Réza, Samadi, Aunia, Samra, Dominic, da Silva, Tiago Sanches, Carrasco, Miguel Andrés Sánchez, Santerne, Alexandre, Pé, Amaia Santiago, Santoli, Francesco, Santos, ngela R. G., Mesa, Rosario Sanz, Sarro, Luis Manuel, Scandariato, Gaetano, Schäfer, Martin, Schlafly, Edward, Schmider, François-Xavier, Schneider, Jean, Schou, Jesper, Schunker, Hannah, Schwarzkopf, Gabriel Jörg, Serenelli, Aldo, Seynaeve, Dries, Shan, Yutong, Shapiro, Alexander, Shipman, Russel, Sicilia, Daniela, sanmartin, Maria Angeles Sierra, Sigot, Axelle, Silliman, Kyle, Silvotti, Roberto, Simon, Attila E., Napoli, Ricardo Simoyama, Skarka, Marek, Smalley, Barry, Smiljanic, Rodolfo, Smit, Samuel, Smith, Alexis, Smith, Leigh, Snellen, Ignas, Sódor, Ádám, Sohl, Frank, Solanki, Sami K., Sortino, Francesca, Sousa, Sérgio, Southworth, John, Souto, Diogo, Sozzetti, Alessandro, Stamatellos, Dimitris, Stassun, Keivan, Steller, Manfred, Stello, Dennis, Stelzer, Beate, Stiebeler, Ulrike, Stokholm, Amalie, Storelvmo, Trude, Strassmeier, Klaus, Strøm, Paul Anthony, Strugarek, Antoine, Sulis, Sophia, vanda, Michal, Szabados, László, Szabó, Róbert, Szabó, Gyula M., Szuszkiewicz, Ewa, Talens, Geert Jan, Teti, Daniele, Theisen, Tom, Thévenin, Frédéric, Thoul, Anne, Tiphene, Didier, Titz-Weider, Ruth, Tkachenko, Andrew, Tomecki, Daniel, Tonfat, Jorge, Tosi, Nicola, Trampedach, Regner, Traven, Gregor, Triaud, Amaury, Trønnes, Reidar, Tsantaki, Maria, Tschentscher, Matthias, Turin, Arnaud, Tvaruzka, Adam, Ulmer, Bernd, Ulmer-Moll, Solène, Ulusoy, Ceren, Umbriaco, Gabriele, Valencia, Diana, Valentini, Marica, Valio, Adriana, Guijarro, Ángel Luis Valverde, Van Eylen, Vincent, Van Grootel, Valerie, van Kempen, Tim A., Van Reeth, Timothy, Van Zelst, Iris, Vandenbussche, Bart, Vasiliou, Konstantinos, Vasilyev, Valeriy, de Mascarenhas, David Vaz, Vazan, Allona, Nunez, Marina Vela, Velloso, Eduardo Nunes, Ventura, Rita, Ventura, Paolo, Venturini, Julia, Trallero, Isabel Vera, Veras, Dimitri, Verdugo, Eva, Verma, Kuldeep, Vibert, Didier, Martinez, Tobias Vicanek, Vida, Krisztián, Vigan, Arthur, Villacorta, Antonio, Villaver, Eva, Aparicio, Marcos Villaverde, Viotto, Valentina, Vorobyov, Eduard, Vorontsov, Sergey, Wagner, Frank W., Walloschek, Thomas, Walton, Nicholas, Walton, Dave, Wang, Haiyang, Waters, Rens, Watson, Christopher, Wedemeyer, Sven, Weeks, Angharad, Weingrill, Jörg, Weiss, Annita, Wendler, Belinda, West, Richard, Westerdorff, Karsten, Westphal, Pierre-Amaury, Wheatley, Peter, White, Tim, Whittaker, Amadou, Wickhusen, Kai, Wilson, Thomas, Windsor, James, Winter, Othon, Winther, Mark Lykke, Winton, Alistair, Witteck, Ulrike, Witzke, Veronika, Woitke, Peter, Wolter, David, Wuchterl, Günther, Wyatt, Mark, Yang, Dan, Yu, Jie, Sanchez, Ricardo Zanmar, Osorio, María Rosa Zapatero, Zechmeister, Mathias, Zhou, Yixiao, Ziemke, Claas, and Zwintz, Konstanze
- Subjects
Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
PLATO (PLAnetary Transits and Oscillations of stars) is ESA's M3 mission designed to detect and characterise extrasolar planets and perform asteroseismic monitoring of a large number of stars. PLATO will detect small planets (down to <2 R_(Earth)) around bright stars (<11 mag), including terrestrial planets in the habitable zone of solar-like stars. With the complement of radial velocity observations from the ground, planets will be characterised for their radius, mass, and age with high accuracy (5 %, 10 %, 10 % for an Earth-Sun combination respectively). PLATO will provide us with a large-scale catalogue of well-characterised small planets up to intermediate orbital periods, relevant for a meaningful comparison to planet formation theories and to better understand planet evolution. It will make possible comparative exoplanetology to place our Solar System planets in a broader context. In parallel, PLATO will study (host) stars using asteroseismology, allowing us to determine the stellar properties with high accuracy, substantially enhancing our knowledge of stellar structure and evolution. The payload instrument consists of 26 cameras with 12cm aperture each. For at least four years, the mission will perform high-precision photometric measurements. Here we review the science objectives, present PLATO's target samples and fields, provide an overview of expected core science performance as well as a description of the instrument and the mission profile at the beginning of the serial production of the flight cameras. PLATO is scheduled for a launch date end 2026. This overview therefore provides a summary of the mission to the community in preparation of the upcoming operational phases.
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- 2024
28. The computational power of random quantum circuits in arbitrary geometries
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DeCross, Matthew, Haghshenas, Reza, Liu, Minzhao, Rinaldi, Enrico, Gray, Johnnie, Alexeev, Yuri, Baldwin, Charles H., Bartolotta, John P., Bohn, Matthew, Chertkov, Eli, Cline, Julia, Colina, Jonhas, DelVento, Davide, Dreiling, Joan M., Foltz, Cameron, Gaebler, John P., Gatterman, Thomas M., Gilbreth, Christopher N., Giles, Joshua, Gresh, Dan, Hall, Alex, Hankin, Aaron, Hansen, Azure, Hewitt, Nathan, Hoffman, Ian, Holliman, Craig, Hutson, Ross B., Jacobs, Trent, Johansen, Jacob, Lee, Patricia J., Lehman, Elliot, Lucchetti, Dominic, Lykov, Danylo, Madjarov, Ivaylo S., Mathewson, Brian, Mayer, Karl, Mills, Michael, Niroula, Pradeep, Pino, Juan M., Roman, Conrad, Schecter, Michael, Siegfried, Peter E., Tiemann, Bruce G., Volin, Curtis, Walker, James, Shaydulin, Ruslan, Pistoia, Marco, Moses, Steven. A., Hayes, David, Neyenhuis, Brian, Stutz, Russell P., and Foss-Feig, Michael
- Subjects
Quantum Physics - Abstract
Empirical evidence for a gap between the computational powers of classical and quantum computers has been provided by experiments that sample the output distributions of two-dimensional quantum circuits. Many attempts to close this gap have utilized classical simulations based on tensor network techniques, and their limitations shed light on the improvements to quantum hardware required to frustrate classical simulability. In particular, quantum computers having in excess of $\sim 50$ qubits are primarily vulnerable to classical simulation due to restrictions on their gate fidelity and their connectivity, the latter determining how many gates are required (and therefore how much infidelity is suffered) in generating highly-entangled states. Here, we describe recent hardware upgrades to Quantinuum's H2 quantum computer enabling it to operate on up to $56$ qubits with arbitrary connectivity and $99.843(5)\%$ two-qubit gate fidelity. Utilizing the flexible connectivity of H2, we present data from random circuit sampling in highly connected geometries, doing so at unprecedented fidelities and a scale that appears to be beyond the capabilities of state-of-the-art classical algorithms. The considerable difficulty of classically simulating H2 is likely limited only by qubit number, demonstrating the promise and scalability of the QCCD architecture as continued progress is made towards building larger machines., Comment: Includes minor updates to the text and an updated author list to include researchers who made technical contributions in upgrading the machine to 56 qubits but were left off the original version by mistake
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- 2024
29. Modelling Alumina Feeding and Transport in an Industrial Aluminium Reduction Cell Using a Pragmatic Computational Model
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Vachaparambil, Kurian J., Johansen, Stein Tore, Soncini, Ryan M., Solheim, Asbjørn, Einarsrud, Kristian Etienne, Elstad, Kim Ronny, and Tessier, Jayson
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- 2025
- Full Text
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30. The antitumor activity of TGFβ-specific T cells is dependent on IL-6 signaling
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Perez-Penco, Maria, Byrdal, Mikkel, Lara de la Torre, Lucia, Ballester, Marta, Khan, Shawez, Siersbæk, Majken, Lecoq, Inés, Madsen, Cecilie Oelvang, Kjeldsen, Julie Westerlin, Svane, Inge Marie, Hansen, Morten, Donia, Marco, Johansen, Julia Sidenius, Olsen, Lars Rønn, Grøntved, Lars, Chen, Inna Markovna, Arnes, Luis, Holmström, Morten Orebo, and Andersen, Mads Hald
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- 2025
- Full Text
- View/download PDF
31. ACE2 and TMPRSS2 in human kidney tissue and urine extracellular vesicles with age, sex, and COVID-19
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Bach, Marie Lykke, Laftih, Sara, Andresen, Jesper K., Pedersen, Rune M., Andersen, Thomas Emil, Madsen, Lone W., Madsen, Kirsten, Hinrichs, Gitte R., Zachar, Rikke, Svenningsen, Per, Lund, Lars, Johansen, Isik S., Hansen, Lennart Friis, Palarasah, Yaseelan, and Jensen, Boye L.
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- 2025
- Full Text
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32. Integrated multimodal cell atlas of Alzheimer’s disease
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Gabitto, Mariano I., Travaglini, Kyle J., Rachleff, Victoria M., Kaplan, Eitan S., Long, Brian, Ariza, Jeanelle, Ding, Yi, Mahoney, Joseph T., Dee, Nick, Goldy, Jeff, Melief, Erica J., Agrawal, Anamika, Kana, Omar, Zhen, Xingjian, Barlow, Samuel T., Brouner, Krissy, Campos, Jazmin, Campos, John, Carr, Ambrose J., Casper, Tamara, Chakrabarty, Rushil, Clark, Michael, Cool, Jonah, Dalley, Rachel, Darvas, Martin, Ding, Song-Lin, Dolbeare, Tim, Egdorf, Tom, Esposito, Luke, Ferrer, Rebecca, Fleckenstein, Lynn E., Gala, Rohan, Gary, Amanda, Gelfand, Emily, Gloe, Jessica, Guilford, Nathan, Guzman, Junitta, Hirschstein, Daniel, Ho, Windy, Hupp, Madison, Jarsky, Tim, Johansen, Nelson, Kalmbach, Brian E., Keene, Lisa M., Khawand, Sarah, Kilgore, Mitchell D., Kirkland, Amanda, Kunst, Michael, Lee, Brian R., Leytze, Mckaila, Mac Donald, Christine L., Malone, Jocelin, Maltzer, Zoe, Martin, Naomi, McCue, Rachel, McMillen, Delissa, Mena, Gonzalo, Meyerdierks, Emma, Meyers, Kelly P., Mollenkopf, Tyler, Montine, Mark, Nolan, Amber L., Nyhus, Julie K., Olsen, Paul A., Pacleb, Maiya, Pagan, Chelsea M., Peña, Nicholas, Pham, Trangthanh, Pom, Christina Alice, Postupna, Nadia, Rimorin, Christine, Ruiz, Augustin, Saldi, Giuseppe A., Schantz, Aimee M., Shapovalova, Nadiya V., Sorensen, Staci A., Staats, Brian, Sullivan, Matt, Sunkin, Susan M., Thompson, Carol, Tieu, Michael, Ting, Jonathan T., Torkelson, Amy, Tran, Tracy, Valera Cuevas, Nasmil J., Walling-Bell, Sarah, Wang, Ming-Qiang, Waters, Jack, Wilson, Angela M., Xiao, Ming, Haynor, David, Gatto, Nicole M., Jayadev, Suman, Mufti, Shoaib, Ng, Lydia, Mukherjee, Shubhabrata, Crane, Paul K., Latimer, Caitlin S., Levi, Boaz P., Smith, Kimberly A., Close, Jennie L., Miller, Jeremy A., Hodge, Rebecca D., Larson, Eric B., Grabowski, Thomas J., Hawrylycz, Michael, Keene, C. Dirk, and Lein, Ed S.
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- 2024
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33. Transatlantic differences in the use and outcome of minimally invasive pancreatoduodenectomy: an international multi-registry analysis
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de Graaf, Nine, Augustinus, Simone, Wellner, Ulrich F., Johansen, Karin, Andersson, Bodil, Beane, Joal D., Björnsson, Bergthor, Busch, Olivier R., Davis, Catherine H., Ghadimi, Michael, Gleeson, Elizabeth M., Groot Koerkamp, Bas, Hogg, Melissa E., van Santvoort, Hjalmar C., Tingstedt, Bobby, Uhl, Waldemar, Werner, Jens, Williamsson, Caroline, Zeh, Herbert J., Zureikat, Amer H., Abu Hilal, Mohammad, Pitt, Henry A., Besselink, Marc G., and Keck, Tobias
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- 2024
- Full Text
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34. Automatic docking with extended dynamic positioning
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Larsen, Stefan, Helgesen, Håkon Hagen, Walmsness, Jens Emil, Kufoalor, Giorgio Kwame Minde, and Johansen, Tor Arne
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- 2024
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35. Precision and accuracy of four handheld blood lactate analyzers across low to high exercise intensities
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Mentzoni, Fredrik, Skaugen, Martin, Eythorsdottir, Ingrid, Roterud, Stian, Johansen, Espen Spro, and Losnegard, Thomas
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- 2024
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36. Evaluating Digital Citizen Participation in Smart Cities
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Adhikari, Aashish, Afshari, Mahgol, Collins, Dave, Salaj, Alenka Temeljotov, Johansen, Agnar, di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Cui, Zhen-Dong, Series Editor, Lu, Xinzheng, Series Editor, Kioumarsi, Mahdi, editor, and Shafei, Behrouz, editor
- Published
- 2025
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37. Giving a Boost to Textbook Tasks
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Van den Heuvel-Panhuizen, Marja, Madsen, Dag Oskar, Alstad, Monica, Breckan, Ruth-Amalie, Johansen, Anne Marthe, Qi, Chunxia, editor, Fan, Lianghuo, editor, Liu, Jian, editor, Liu, Qimeng, editor, and Dong, Lianchun, editor
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- 2025
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38. Human P2X7 receptor variants Gly150Arg and Arg276His polymorphisms have differential effects on risk association and cellular functions in pancreatic cancer
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Magni, Lara, Yu, Haoran, Christensen, Nynne M., Poulsen, Mette H., Frueh, Alexander, Deshar, Ganga, Johansen, Astrid Z., Johansen, Julia S., Pless, Stephan A., Jørgensen, Niklas R., and Novak, Ivana
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- 2024
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39. A correspondence between Maxwell--Einstein theory and superfluidity
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Johansen, Emil Génetay
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Condensed Matter - Quantum Gases ,General Relativity and Quantum Cosmology ,High Energy Physics - Theory - Abstract
A planar superfluid is considered and interpreted in terms of electromagnetism and gravity. It has previously been suggested that the superfluid flow can be regarded as analogous to an electromagnetic field and that a non-vanishing density gradient give rise to a gravity-like force. The present work seeks to reconcile these hitherto distinct pictures into a unified exposition of vortex electrodynamics in a curved analogue space-time. By constructing a theory in which the planar Maxwell's equations are coupled to a (d+1)-dimensional conformally curved space-time, we expose a correspondence between the resulting equations of motion of the embedded fields and the dynamics of a quantum fluid. Finally, an effective vortex metric whose connection components are torsional is studied and its effect on the superfluid Maxwell's equations is elucidated upon., Comment: 9 pages
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- 2024
40. Fast formation of large ice pebbles after FU Orionis outbursts
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Ros, Katrin and Johansen, Anders
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Astrophysics - Earth and Planetary Astrophysics - Abstract
During their formation, nascent planetary systems are subject to FU Orionis outbursts that heat a substantial part of the disc. This causes water ice in the affected part of the disc to sublimate as the ice line moves outwards to several to tens of astronomical units. In this paper, we investigate how the subsequent cooling of the disc impacts the particle sizes. We calculate the resulting particle sizes in a disc model with cooling times between 100 and 1,000 years, corresponding to typical FU Orionis outbursts. As the disc cools and the ice line retreats inwards, water vapour forms icy mantles on existing silicate particles. This process is called heterogeneous nucleation. The nucleation rate per surface area of silicate substrate strongly depends on the degree of super-saturation of the water vapour in the gas. Fast cooling results in high super-saturation levels, high nucleation rates, and limited condensation growth because the main ice budget is spent in the nucleation. Slow cooling, on the other hand, leads to rare ice nucleation and efficient growth of ice-nucleated particles by subsequent condensation. We demonstrate that close to the quiescent ice line, pebbles with a size of about centimetres to decimetres form by this process. The largest of these are expected to undergo cracking collisions. However, their Stokes numbers still reach values that are high enough to potentially trigger planetesimal formation by the streaming instability if the background turbulence is weak. Stellar outbursts may thus promote planetesimal formation around the water ice line in protoplanetary discs., Comment: Accepted for publication in Astronomy & Astrophysics. 8 pages, 6 figures
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- 2024
- Full Text
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41. How the presence of a giant planet affects the outcome of terrestrial planet formation simulations
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Kong, Zhihui, Johansen, Anders, Lambrechts, Michiel, Jiang, Jonathan H., and Zhu, Zong-Hong
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Astrophysics - Earth and Planetary Astrophysics - Abstract
The architecture and masses of planetary systems in the habitable zone could be strongly influenced by outer giant planets, if present. We investigate here the impact of outer giants on terrestrial planet formation, under the assumption that the final assembly of the planetary system is set by a giant impact phase. Utilizing a state-of-the-art N-body simulation software, GENGA, we interpret how the late stage of terrestrial planet formation results in diversity within planetary systems. We design two global model setups: in the first we place a gas giant on the outer side of planetesimals and embryos disk, while the other only has planetesimals and embryos but no giant. For the model including the outer giant, we study the effect of different giant initial masses, in the range 1.0-3.0 Jupiter mass, and orbital radii, in the range 2.0-5.8 AU.We also study the influence of different initial positions of planetesimals and embryos on the results. Our N-body simulation time is approximately 50 Myr. The results show that the existence of outer giant will promote the interaction between planetesimals and embryos, making the orbits of the formed terrestrial planets more compact, but placing the giant planet too close to the planetesimals and embryos disk suppresses the formation of massive rocky planets. In addition, under the classical theory, where planetary embryos and planetesimals collide to form terrestrial planets, our results show that the presence of a giant planet actually decreases the gap complexity of the inner planetary system., Comment: 12 pages, 15 figures
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- 2024
- Full Text
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42. Optimal Treatment Allocation under Constraints
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Johansen, Torben S. D.
- Subjects
Economics - Econometrics - Abstract
In optimal policy problems where treatment effects vary at the individual level, optimally allocating treatments to recipients is complex even when potential outcomes are known. We present an algorithm for multi-arm treatment allocation problems that is guaranteed to find the optimal allocation in strongly polynomial time, and which is able to handle arbitrary potential outcomes as well as constraints on treatment requirement and capacity. Further, starting from an arbitrary allocation, we show how to optimally re-allocate treatments in a Pareto-improving manner. To showcase our results, we use data from Danish nurse home visiting for infants. We estimate nurse specific treatment effects for children born 1959-1967 in Copenhagen, comparing nurses against each other. We exploit random assignment of newborn children to nurses within a district to obtain causal estimates of nurse-specific treatment effects using causal machine learning. Using these estimates, and treating the Danish nurse home visiting program as a case of an optimal treatment allocation problem (where a treatment is a nurse), we document room for significant productivity improvements by optimally re-allocating nurses to children. Our estimates suggest that optimal allocation of nurses to children could have improved average yearly earnings by USD 1,815 and length of education by around two months.
- Published
- 2024
43. High-fidelity and Fault-tolerant Teleportation of a Logical Qubit using Transversal Gates and Lattice Surgery on a Trapped-ion Quantum Computer
- Author
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Ryan-Anderson, C., Brown, N. C., Baldwin, C. H., Dreiling, J. M., Foltz, C., Gaebler, J. P., Gatterman, T. M., Hewitt, N., Holliman, C., Horst, C. V., Johansen, J., Lucchetti, D., Mengle, T., Matheny, M., Matsuoka, Y., Mayer, K., Mills, M., Moses, S. A., Neyenhuis, B., Pino, J., Siegfried, P., Stutz, R. P., Walker, J., and Hayes, D.
- Subjects
Quantum Physics - Abstract
Quantum state teleportation is commonly used in designs for large-scale fault-tolerant quantum computers. Using Quantinuum's H2 trapped-ion quantum processor, we implement the first demonstration of a fault-tolerant state teleportation circuit for a quantum error correction code - in particular, the planar topological [[7,1,3]] color code, or Steane code. The circuits use up to 30 trapped ions at the physical layer qubits and employ real-time quantum error correction - decoding mid-circuit measurement of syndromes and implementing corrections during the protocol. We conduct experiments on several variations of logical teleportation circuits using both transversal gates and lattice surgery protocols. Among the many measurements we report on, we measure the logical process fidelity of the transversal teleportation circuit to be 0.975(2) and the logical process fidelity of the lattice surgery teleportation circuit to be 0.851(9). Additionally, we run a teleportation circuit that is equivalent to Knill-style quantum error correction and measure the process fidelity to be 0.989(2).
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- 2024
44. The Brain Tumor Segmentation in Pediatrics (BraTS-PEDs) Challenge: Focus on Pediatrics (CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs)
- Author
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Kazerooni, Anahita Fathi, Khalili, Nastaran, Liu, Xinyang, Gandhi, Deep, Jiang, Zhifan, Anwar, Syed Muhammed, Albrecht, Jake, Adewole, Maruf, Anazodo, Udunna, Anderson, Hannah, Baid, Ujjwal, Bergquist, Timothy, Borja, Austin J., Calabrese, Evan, Chung, Verena, Conte, Gian-Marco, Dako, Farouk, Eddy, James, Ezhov, Ivan, Familiar, Ariana, Farahani, Keyvan, Franson, Andrea, Gottipati, Anurag, Haldar, Shuvanjan, Iglesias, Juan Eugenio, Janas, Anastasia, Johansen, Elaine, Jones, Blaise V, Khalili, Neda, Kofler, Florian, LaBella, Dominic, Lai, Hollie Anne, Van Leemput, Koen, Li, Hongwei Bran, Maleki, Nazanin, McAllister, Aaron S, Meier, Zeke, Menze, Bjoern, Moawad, Ahmed W, Nandolia, Khanak K, Pavaine, Julija, Piraud, Marie, Poussaint, Tina, Prabhu, Sanjay P, Reitman, Zachary, Rudie, Jeffrey D, Sanchez-Montano, Mariana, Shaikh, Ibraheem Salman, Sheth, Nakul, Tu, Wenxin, Wang, Chunhao, Ware, Jeffrey B, Wiestler, Benedikt, Zapaishchykova, Anna, Bornhorst, Miriam, Deutsch, Michelle, Fouladi, Maryam, Lazow, Margot, Mikael, Leonie, Hummel, Trent, Kann, Benjamin, de Blank, Peter, Hoffman, Lindsey, Aboian, Mariam, Nabavizadeh, Ali, Packer, Roger, Bakas, Spyridon, Resnick, Adam, Rood, Brian, Vossough, Arastoo, and Linguraru, Marius George
- Subjects
Computer Science - Computer Vision and Pattern Recognition ,Electrical Engineering and Systems Science - Image and Video Processing - Abstract
Pediatric tumors of the central nervous system are the most common cause of cancer-related death in children. The five-year survival rate for high-grade gliomas in children is less than 20%. Due to their rarity, the diagnosis of these entities is often delayed, their treatment is mainly based on historic treatment concepts, and clinical trials require multi-institutional collaborations. Here we present the CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs challenge, focused on pediatric brain tumors with data acquired across multiple international consortia dedicated to pediatric neuro-oncology and clinical trials. The CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs challenge brings together clinicians and AI/imaging scientists to lead to faster development of automated segmentation techniques that could benefit clinical trials, and ultimately the care of children with brain tumors., Comment: arXiv admin note: substantial text overlap with arXiv:2305.17033
- Published
- 2024
45. Robotic Blended Sonification: Consequential Robot Sound as Creative Material for Human-Robot Interaction
- Author
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Johansen, Stine S., Browning, Yanto, Brumpton, Anthony, Donovan, Jared, and Rittenbruch, Markus
- Subjects
Computer Science - Human-Computer Interaction ,Computer Science - Robotics ,Computer Science - Sound ,Electrical Engineering and Systems Science - Audio and Speech Processing - Abstract
Current research in robotic sounds generally focuses on either masking the consequential sound produced by the robot or on sonifying data about the robot to create a synthetic robot sound. We propose to capture, modify, and utilise rather than mask the sounds that robots are already producing. In short, this approach relies on capturing a robot's sounds, processing them according to contextual information (e.g., collaborators' proximity or particular work sequences), and playing back the modified sound. Previous research indicates the usefulness of non-semantic, and even mechanical, sounds as a communication tool for conveying robotic affect and function. Adding to this, this paper presents a novel approach which makes two key contributions: (1) a technique for real-time capture and processing of consequential robot sounds, and (2) an approach to explore these sounds through direct human-robot interaction. Drawing on methodologies from design, human-robot interaction, and creative practice, the resulting 'Robotic Blended Sonification' is a concept which transforms the consequential robot sounds into a creative material that can be explored artistically and within application-based studies., Comment: Paper accepted at ISEA 24, The 29th International Symposium on Electronic Art, Brisbane, Australia, 21-29 June 2024
- Published
- 2024
46. Weight Copy and Low-Rank Adaptation for Few-Shot Distillation of Vision Transformers
- Author
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Grigore, Diana-Nicoleta, Georgescu, Mariana-Iuliana, Justo, Jon Alvarez, Johansen, Tor, Ionescu, Andreea Iuliana, and Ionescu, Radu Tudor
- Subjects
Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Artificial Intelligence ,Computer Science - Machine Learning - Abstract
Few-shot knowledge distillation recently emerged as a viable approach to harness the knowledge of large-scale pre-trained models, using limited data and computational resources. In this paper, we propose a novel few-shot feature distillation approach for vision transformers. Our approach is based on two key steps. Leveraging the fact that vision transformers have a consistent depth-wise structure, we first copy the weights from intermittent layers of existing pre-trained vision transformers (teachers) into shallower architectures (students), where the intermittence factor controls the complexity of the student transformer with respect to its teacher. Next, we employ an enhanced version of Low-Rank Adaptation (LoRA) to distill knowledge into the student in a few-shot scenario, aiming to recover the information processing carried out by the skipped teacher layers. We present comprehensive experiments with supervised and self-supervised transformers as teachers, on six data sets from various domains (natural, medical and satellite images) and tasks (classification and segmentation). The empirical results confirm the superiority of our approach over state-of-the-art competitors. Moreover, the ablation results demonstrate the usefulness of each component of the proposed pipeline. We release our code at https://github.com/dianagrigore/WeCoLoRA., Comment: Accepted at WACV 2025
- Published
- 2024
47. Benchmarking logical three-qubit quantum Fourier transform encoded in the Steane code on a trapped-ion quantum computer
- Author
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Mayer, Karl, Ryan-Anderson, Ciarán, Brown, Natalie, Durso-Sabina, Elijah, Baldwin, Charles H., Hayes, David, Dreiling, Joan M., Foltz, Cameron, Gaebler, John P., Gatterman, Thomas M., Gerber, Justin A., Gilmore, Kevin, Gresh, Dan, Hewitt, Nathan, Horst, Chandler V., Johansen, Jacob, Mengle, Tanner, Mills, Michael, Moses, Steven A., Siegfried, Peter E., Neyenhuis, Brian, Pino, Juan, and Stutz, Russell
- Subjects
Quantum Physics - Abstract
We implement logically encoded three-qubit circuits for the quantum Fourier transform (QFT), using the [[7,1,3]] Steane code, and benchmark the circuits on the Quantinuum H2-1 trapped-ion quantum computer. The circuits require multiple logical two-qubit gates, which are implemented transversally, as well as logical non-Clifford single-qubit rotations, which are performed by non-fault-tolerant state preparation followed by a teleportation gadget. First, we benchmark individual logical components using randomized benchmarking for the logical two-qubit gate, and a Ramsey-type experiment for the logical $T$ gate. We then implement the full QFT circuit, using two different methods for performing a logical control-$T$, and benchmark the circuits by applying it to each basis state in a set of bases that is sufficient to lower bound the process fidelity. We compare the logical QFT benchmark results to predictions based on the logical component benchmarks.
- Published
- 2024
48. Demonstration of logical qubits and repeated error correction with better-than-physical error rates
- Author
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Paetznick, A., da Silva, M. P., Ryan-Anderson, C., Bello-Rivas, J. M., Campora III, J. P., Chernoguzov, A., Dreiling, J. M., Foltz, C., Frachon, F., Gaebler, J. P., Gatterman, T. M., Grans-Samuelsson, L., Gresh, D., Hayes, D., Hewitt, N., Holliman, C., Horst, C. V., Johansen, J., Lucchetti, D., Matsuoka, Y., Mills, M., Moses, S. A., Neyenhuis, B., Paz, A., Pino, J., Siegfried, P., Sundaram, A., Tom, D., Wernli, S. J., Zanner, M., Stutz, R. P., and Svore, K. M.
- Subjects
Quantum Physics - Abstract
The promise of quantum computers hinges on the ability to scale to large system sizes, e.g., to run quantum computations consisting of more than 100 million operations fault-tolerantly. This in turn requires suppressing errors to levels inversely proportional to the size of the computation. As a step towards this ambitious goal, we present experiments on a trapped-ion QCCD processor where, through the use of fault-tolerant encoding and error correction, we are able to suppress logical error rates to levels below the physical error rates. In particular, we entangled logical qubits encoded in the [[7,1,3]] code with error rates 9.8 times to 500 times lower than at the physical level, and entangled logical qubits encoded in a [[12,2,4]] code based on Knill's C4/C6 scheme with error rates 4.7 times to 800 times lower than at the physical level, depending on the judicious use of post-selection. Moreover, we demonstrate repeated error correction with the [[12,2,4]] code, with logical error rates below physical circuit baselines corresponding to repeated CNOTs, and show evidence that the error rate per error correction cycle, which consists of over 100 physical CNOTs, approaches the error rate of two physical CNOTs. These results signify a transition from noisy intermediate scale quantum computing to reliable quantum computing, and demonstrate advanced capabilities toward large-scale fault-tolerant quantum computing., Comment: (v1) 13 pages, 8 figures; (v2) Fixed typos, added authors; (v3) Added Carbon details (instead of separate article), improved decoder, got more data, added authors, fixed misinterpreted physical teleportation baseline, added a figure, and fixed typos
- Published
- 2024
49. Substrate, temperature and magnetic field dependence of electric polarisation in mixed-stacking tetralayer graphenes
- Author
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Sarsfield, Patrick Johansen, Garcia-Ruiz, Aitor, and Fal'ko, Vladimir I.
- Subjects
Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
Polytypes of tetralayer graphene (TLG: Bernal, rhombohedral and mixed stacking) are crystalline structures with different symmetries. Among those, mixed-stacking tetralayers lack inversion symmetry, which allows for intrinsic spontaneous out-of-plane electrical polarisation, inverted in the mirror-image pair, ABCB and ABAC stackings. Here, we compare the intrinsic polarisation of such TLGs with the symmetry-breaking effect of a substrate, which can also generate out-of-plane electric dipole moments with different sizes in all four polytypes, including ABCB and ABAC twins. We analyse their temperature and magnetic field dependence, in view of understanding the origin of the recently measured Kelvin probe force microscopy maps of tetralayer flakes, and notice that the intrinsic contribution could be singled out based on magnetic field dependence of polarisation measured at low temperatures., Comment: 11 pages, 8 figures
- Published
- 2024
50. Deep Learning for In-Orbit Cloud Segmentation and Classification in Hyperspectral Satellite Data
- Author
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Kovac, Daniel, Mucha, Jan, Justo, Jon Alvarez, Mekyska, Jiri, Galaz, Zoltan, Novotny, Krystof, Pitonak, Radoslav, Knezik, Jan, Herec, Jonas, and Johansen, Tor Arne
- Subjects
Computer Science - Computer Vision and Pattern Recognition ,Electrical Engineering and Systems Science - Image and Video Processing - Abstract
This article explores the latest Convolutional Neural Networks (CNNs) for cloud detection aboard hyperspectral satellites. The performance of the latest 1D CNN (1D-Justo-LiuNet) and two recent 2D CNNs (nnU-net and 2D-Justo-UNet-Simple) for cloud segmentation and classification is assessed. Evaluation criteria include precision and computational efficiency for in-orbit deployment. Experiments utilize NASA's EO-1 Hyperion data, with varying spectral channel numbers after Principal Component Analysis. Results indicate that 1D-Justo-LiuNet achieves the highest accuracy, outperforming 2D CNNs, while maintaining compactness with larger spectral channel sets, albeit with increased inference times. However, the performance of 1D CNN degrades with significant channel reduction. In this context, the 2D-Justo-UNet-Simple offers the best balance for in-orbit deployment, considering precision, memory, and time costs. While nnU-net is suitable for on-ground processing, deployment of lightweight 1D-Justo-LiuNet is recommended for high-precision applications. Alternatively, lightweight 2D-Justo-UNet-Simple is recommended for balanced costs between timing and precision in orbit., Comment: Hyperspectral Satellite Data, Cloud Segmentation, Classification, Convolutional Neural Networks, Principal Component Analysis
- Published
- 2024
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