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2. Peritoneal carcinomatosis and prostatic cancer : a rare manifestation of the disease with an impact on management

Author

M Ghaddab, E Danse, J P Machiels, A Dragean, L Annet, and B Tombal

Subjects
Medical physics. Medical radiology. Nuclear medicine, R895-920
Abstract

As it has been recently noted in two papers published in the JBRTBR (1, 2), prostate cancer is the second cause of male-cancer related death. The role of radiologists is crucial at the early stage of the disease, for local and distant staging, and during the follow up of the patient. We would like to take the opportunity to report on an uncommon case of peritoneal carcinomatosis observed during the long term follow up of a patient having prostate cancer. Based on these findings, there was a need for change of therapy, with a positive impact on the outcome.

Published
2013
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3. Diffuse b-cell lymphoma

Author

C Grosu, E Danse, A Dragean, and L Annet

Subjects
Lymphoma, AIDS-related, Medical physics. Medical radiology. Nuclear medicine, R895-920
Abstract

Background: A 39-year-old patient took medical advice because of progressive fatigue, with nausea, fever, non specific abdominal pain, 3 weeks after coming back from Asia. He had been positive for HIV for 6 years. Blood tests show an increased CRP level (4 mg/dl, nl < 1 mg/dl).

Published
2011
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4. Unusually Hypervascularized Liver Lesion

Author

Eya Chaouch, Selda Aydin, and Dragean Cristina Anca

Subjects
microcystic, liver, lymphangioma, mri, Medical physics. Medical radiology. Nuclear medicine, R895-920
Abstract

Teaching point: Microcystic lymphangioma is a rare but benign lesion that should be differentiated from a neoplasm.

Published
2024
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5. Abnormal Origin of the Left Coronary Artery: When the Bloodstream Finds its Way

Author

Amin Mahsouli and Cristina Anca Dragean

Subjects
alcapa syndrome, lca steal phenomenon, coronary anomaly, myocardial infarction, Medical physics. Medical radiology. Nuclear medicine, R895-920
Abstract

Teaching Point: Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA syndrome) is a rare congenital anomaly characterized by a steal phenomenon; it must be recognized, as a prompt treatment may prevent life-threatening complications such as myocardial infarction, mitral dysfunction, and malignant dysrhythmias in adults.

Published
2023
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6. Anterior Perineum: Between the Gynecological and Urinary Tract

Author

Guillaume Puissant, Cristina Anca Dragean, and Isabelle Leconte

Subjects
urethral diverticulum, pelvis, mri, Medical physics. Medical radiology. Nuclear medicine, R895-920
Abstract

Teaching Point: Female urethral diverticulum is a rare condition that is often a diagnostic challenge; magnetic resonance imaging (MRI) is efficient to confirm the diagnosis (especially if endovaginal ultrasound is inconclusive), to assess the diverticulum prior to surgery, and to detect related complications including intra-diverticular neoplasm.

Published
2023
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8. Schwannoma: A Rare Cause of Perineal Pain

Author

Ophélye Chiabai, Etienne Marbaix, and Cristina Dragean

Subjects
schwannoma, pelvic, rectovaginal septum, Medical physics. Medical radiology. Nuclear medicine, R895-920
Abstract

Teaching point: Unexplained persistent perineal pain poses a differential diagnosis, including pelvic nerve lesions. The rare occurrence of pelvic schwannoma is easily shown by a MRI as a T2-hyperintense enhancing mass.

Published
2022
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10. Retroperitoneal Lympathic Malformations as First Presentation of Lymphangioleiomyomatosis

Author

Christine Lenfant and Cristina Anca Dragean

Subjects
lymphangioleiomyomatosis, retroperitoneum, cystic abdominal mass, lymphatic malformation, mediastinum, Medical physics. Medical radiology. Nuclear medicine, R895-920
Abstract

Teaching Point: This case highlights the extrapulmonary lymphatic abnormalities that may be associated with pulmonary lymphangioleiomyomatosis.

Published
2021
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11. Cryptogenic multifocal ulcerative stenosing enteritis (CMUSE) diagnosed by retrograde motorized spiral enteroscopy

Author

M Belhassine, C Dragean, H Dano, and T.G. Moreels

Abstract

We present the case of a 59-years-old woman with a history of abdominal pain and iron-deficiency anemia. Upper and lower gastrointestinal endoscopy turned out negative and further investigation with wireless videocapsule showed an inflammatory stricture in the middle of the small bowel with retention of the videocapsule. Treatment with budesonide was initiated and allowed the spontaneous evacuation of the videocapsule. Retrograde motorized spiral enteroscopy was performed and confirmed an ulcerative stricture 60 cm proximal to the ileocaecal valve. Clinical, iconographic, endoscopic and histological results were compatible with a rare entity described as cryptogenic multifocal ulcerative stenosing enteritis (CMUSE). After the diagnosis budesonide was replaced by azathioprine 100 mg/d as an immunosuppressor. However, azathioprine induced mild pancreatitis and a second course of

Published
2022
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15. Innovations 2022 en chirurgie hépato-bilio-pancréatique

Author

Marique, Lancelot, De Cuyper, Astrid, Annet, Laurence, Dragean, Cristina Anca, Goffette, Pierre, Hoton, Delphine, Lhommel, Renaud, Van Ooteghem, Geneviève, Borbath, Ivan, Hubert, Catherine, UCL - (SLuc) Service de chirurgie et transplantation abdominale, UCL - (SLuc) Unité d'oncologie médicale, UCL - (SLuc) Centre du cancer, UCL - SSS/IREC/IMAG - Pôle d'imagerie médicale, UCL - (SLuc) Service de radiologie, UCL - SSS/IONS/NEUR - Clinical Neuroscience, UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Service d'anatomie pathologique, UCL - SSS/IREC/MIRO - Pôle d'imagerie moléculaire, radiothérapie et oncologie, UCL - (SLuc) Service de médecine nucléaire, UCL - (SLuc) Service de radiothérapie oncologique, UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - (SLuc) Service d'hépato-gastro-entérologie, and UCL - SSS/IREC/CHEX - Pôle de chirgurgie expérimentale et transplantation

Subjects
Adénocarcinome, Pancréas, Réponse pathologique complète, Traitement néoadjuvant, Chirurgie, Chimiothérapie, Cancer, Radiothérapie
Abstract

Innovations dans la prise en charge de l’adénocarcinome pancréatique « limite résécable » ou « localement avancé », en 2022 : que retenir ? L’année 2022 a été riche en innovations dans la prise en charge de l’adénocarcinome du pancréas borderline ou localement avancé et offre de nouvelles opportunités de traitements multimodaux aux Cliniques universitaires Saint-Luc. Nous vous illustrons ici par deux histoires cliniques, l’importance de la prise en charge pluridisciplinaire pour ce type de patients. Nous vous détaillons ensuite, par spécialité, les innovations et spécificités propres à chacun, dont l’expertise est capitale au sein du groupe.

Published
2023

18. Acute Pain in Right Iliac Fossa during Pregnancy

Author

Chiabai, Ophelye and Dragean, Cristina Anca

Subjects
education, radiology, gastroenterology, Radiology, Nuclear Medicine and imaging, Epiploic appendagitis, right iliac fossa, pregnancy
Abstract

Teaching Point: The diagnosis of epiploic appendagitis in case of pain in the right iliac fossa in pregnant woman shouldn’t be forgotten.

Published
2022
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19. A Rare Complication of Appendicostomy

Author

Romain Lacrosse and Cristina Dragean

Subjects
Malone appendicostomy, appendicolith, antegrade continence enema, mental disorders, education, fungi, food and beverages, Abdominal Imaging, Surgery, Radiology, Nuclear Medicine and imaging
Abstract

Teaching Point: The acute appendicitis in a context of Malone appendicostomy complication is very rare but can occur and may be challenging to diagnose due to its unusual position.

Published
2022
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22. Giant idiopathic ulcer of esophagus in the context of acquired immunodeficiency syndrome (AIDS)

Author

CA Dragean, I Bogdan, K Azzouzzi, and L Goncette

Subjects
Acquired immunodeficiency syndrome (AIDS) – Peptic ulcer, Medical physics. Medical radiology. Nuclear medicine, R895-920
Abstract

The giant ulcer of esophagus is a rare entity in the context of human immunodeficiency syndrome. In front of this type of ulceration the radiologist must to distinguish between two types of ulcers HIV, cytomegalovirus (CMV). The differential diagnosis is necessary for orientation of the therapy and is the result of association between radiological, endoscopic and pathological findings.

Published
2013
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23. Virtual unenhanced phase with spectral dual-energy CT: Is it an alternative to conventional true unenhanced phase for abdominal tissues?

Author

S. Jamali, Emmanuel Coche, Cristina Dragean, Nicolas Michoux, UCL - SSS/IREC/IMAG - Pôle d'imagerie médicale, UCL - (SLuc) Service de radiologie, and UCL - SSS/IONS/NEUR - Clinical Neuroscience

Subjects
Adult, Male, Radiography, Abdominal, Adolescent, Image quality, Dual-energy computed tomography (CT), Radiography, Phase (waves), Contrast Media, Projection/methods, Signal-To-Noise Ratio, Radiation Dosage, 030218 nuclear medicine & medical imaging, Radiography, Dual-Energy Scanned Projection, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Humans, Medicine, Radiology, Nuclear Medicine and imaging, Aged, Retrospective Studies, Aged, 80 and over, Radiological and Ultrasound Technology, business.industry, Radiation dose, Attenuation, Dual layer, Dual-Energy Computed Tomography, General Medicine, Middle Aged, 030220 oncology & carcinogenesis, Radiographic Image Interpretation, Computer-Assisted, Female, Radiography, Thoracic, Dual energy ct, Tomography, X-Ray Computed, business, Nuclear medicine
Abstract

Purpose To compare attenuation measurements and image quality of virtual unenhanced phase (VUP) images with those of conventional true unenhanced phase (TUP) images on spectral dual energy computed tomography (DECT) with dual layer detector on abdominal tissues and to assess potential reduction in radiation dose. Material and method A total of 295 patients (185 men, 110 women; mean age 61 ± 17.6 [SD] years [range: 17–95 years]) who had undergone abdominal or thoraco-abdominal CT with pre- and post-contrast imaging (portal phase) with spectral DECT with dual layer detector were retrospectively analyzed. VUP images based on portal-venous phase DECT acquisition were generated. Regions of interest were defined in abdominal tissues (liver, spleen, kidney, muscle and fat) by two independent readers. Inter-technique agreement (VUP images vs. TUP images) on attenuation measurements was assessed. Signal-to noise ratio (SNR) and image quality of TUP and VUP images were compared. The radiation dose delivered to patients was compared with the radiation dose of protocols without TUP images. Results A total of 9880 ROIs were drawn in the abdominal tissues. The difference in mean attenuation values between TUP and VUP images was less than 15 HU in 98.3% and less than 10 HU in 92.3% of all measurements. VUP images overestimated attenuation in fat comparatively to TUP images. Image quality was evaluated as good or excellent in 77% (37/48) of TUP images and 54% (26/48) of VUP images. Using VUP images instead of TUP images could decrease the radiation dose by 32%. Conclusion VUP images demonstrate good agreement with TUP images in different abdominals tissues and can be obtained with similar image quality as TUP. VUP images appear as an alternative to TUP images, resulting in reduction of radiation dose delivered to the patient.

Published
2019
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24. Hepatofugal Portal Venous Flow: From Normal to Pathological

Author

Margaux Collard, Anca Dragean, Marin Halut, and Emmanuel Coche

Subjects
medicine.medical_specialty, business.industry, General Medicine, Blood flow, Venous flow, Patient care, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Flow (mathematics), Portal blood, Medicine, 030211 gastroenterology & hepatology, Radiology, Ultrasonography, business, Pathological
Abstract

Whether segmental or diffuse, a hepatofugal blood flow is almost always pathological. Over the years, Doppler ultrasonography has retained its position as one of the most accessible and physiological imaging techniques to evaluate the direction of the portal blood flow. Detection of a reverse flow is important as it may change patient care and outcome.

Published
2019
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25. Retroperitoneal Lympathic Malformations as First Presentation of Lymphangioleiomyomatosis.

Author

UCL - SSS/IREC/IMAG - Pôle d'imagerie médicale, UCL - (SLuc) Centre du cancer, UCL - (SLuc) Département d'imagerie médicale, Lenfant, Christine, Dragean, Cristina Anca, UCL - SSS/IREC/IMAG - Pôle d'imagerie médicale, UCL - (SLuc) Centre du cancer, UCL - (SLuc) Département d'imagerie médicale, Lenfant, Christine, and Dragean, Cristina Anca

Abstract

This case highlights the extrapulmonary lymphatic abnormalities that may be associated with pulmonary lymphangioleiomyomatosis.

Published
2021

27. Spontaneous Esophageal Rupture or Boerhaave’s Syndrome

Author

Cristina Dragean and François Carrozza

Subjects
lcsh:Medical physics. Medical radiology. Nuclear medicine, medicine.medical_specialty, Boerhaave syndrome, Admittance, Images in Clinical Radiology, lcsh:R895-920, education, Computed tomography, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Boerhaave’s syndrome, spontaneous esophageal rupture, computed tomography, medicine, Radiology, Nuclear Medicine and imaging, Surgical emergency, S syndrome, medicine.diagnostic_test, business.industry, medicine.disease, Spontaneous esophageal rupture, 030220 oncology & carcinogenesis, Radiology, business
Abstract

Teaching point: Boerhaave syndrome is a very rare life-threatening surgical emergency, often misdiagnosed at the patient’s admittance.

Published
2020

30. Imaging of Acute Appendicitis for Adult Patients

Author

V. Passoglou, S. Van Nieuwenhove, Pierre Trefois, Etienne Danse, Laurence Annet, and Cristina Dragean

Subjects
medicine.medical_specialty, medicine.diagnostic_test, business.industry, Ultrasound, Magnetic resonance imaging, Appendix, Contrast medium, medicine.anatomical_structure, Radiological weapon, Acute appendicitis, Medicine, Abdomen, Radiology, business, Pathological
Abstract

Objectives: To describe the normal and pathological radiological appearance of the appendix in the adult patient using ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI). Furthermore, to review the utility of the aforementioned imaging modalities in different clinical contexts. Summary: The diagnosis of an inflamed appendix based on clinical evaluation, biological data and crosssectional imaging. US is the first line technique to consider and is the modality of choice for children, young and thin patients and women of childbearing age. An inconclusive ultrasound examination should lead to the realization of a CT. The appearance of the normal and pathological appendix needs to be clarified, in view of the modern technological developments of US as well as on the basis of the new CT methods (multidetector CT, with or without dual energy, low-dose acquisition). CT examinations can be performed with or without intravenous injection of contrast medium, accompanied by oral or rectal opacification, with variable diagnostic performance depending on the thickness of the sections and the possible use of reconstructions. MRI remains the second most important examination for young patients and pregnant women. In view of such technical progress, the plain films of the abdomen no longer have a role in everyday practice. Conclusion: A better knowledge of the US and cross-sectional appearance (CT-MRI) of the normal or inflamed appendix should allow the radiologist to contribute to an optimal management of this very frequent acute clinical situation. This approach reduces unnecessary radiation and negative appendectomies and optimizes the health care expenditures

Published
2019
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32. Bladder Metastasis of Gastric Adenocarcinoma

Author

Cristina Dragean, Laurence Annet, and Ralph Khoury

Subjects
lcsh:Medical physics. Medical radiology. Nuclear medicine, Pathology, medicine.medical_specialty, business.industry, Bladder, lcsh:R895-920, education, Metastasis, gastric adenocarcinoma, medicine.disease, urologic and male genital diseases, radiology, histopathology, female genital diseases and pregnancy complications, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, Gastric adenocarcinoma, 0302 clinical medicine, 030220 oncology & carcinogenesis, Medicine, Radiology, Nuclear Medicine and imaging, Thickening, Differential diagnosis, business
Abstract

Teaching point: Metastatic involvement has to be considered in the differential diagnosis for diffuse bladder wall thickening

Published
2019

33. Intestinal angioedema from angiotensin converting enzyme inhibitor

Author

Cristina Dragean, Géraldine Dahlqvist, Michel Jadoul, and Valentine Gillion

Subjects
Adult, Angioedema, biology, business.industry, Glomerulosclerosis, Focal Segmental, Glomerulosclerosis, Angiotensin-converting enzyme, Angiotensin-Converting Enzyme Inhibitors, Jejunal Diseases, Pharmacology, medicine.disease, Abdominal Pain, Jejunum, Enalapril, Nephrology, X ray computed, Hypertension, medicine, biology.protein, Humans, Female, medicine.symptom, business, Tomography, X-Ray Computed
Published
2019

34. Intestinal angioedema from ACE-inhibitor

Author

Gillion, Valentine, Dragean, Cristina, Dahlqvist, Géraldine, Jadoul, Michel, UCL - SSS/IREC/NEFR - Pôle de Néphrologie, UCL - (SLuc) Service de néphrologie, UCL - (SLuc) Service de radiologie, UCL - (SLuc) Service de gastro-entérologie, and UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie

Abstract

A 41-year-old Congolese woman born in 1977 presented in February 2018 to our emergency department with severe abdominal pain. Her medical history was notable for idiopathic collapsing glomerulopathy for which she was being initially treated with corticosteroids, later switched to tacrolimus. Additionally she was on candesartan 16 mg/d, then later switched in 2014 to enalapril 20 mg/d. During 2017, she was poorly compliant with her medications. In February 2018, her medications included tacrolimus, furosemide, spironolactone, lercanidipine, and enalapril. [...]

Published
2019

35. Intestinal angioedema from ACE-inhibitor

Author

UCL - SSS/IREC/NEFR - Pôle de Néphrologie, UCL - (SLuc) Service de néphrologie, UCL - (SLuc) Service de radiologie, UCL - (SLuc) Service de gastro-entérologie, UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, Gillion, Valentine, Dragean, Cristina, Dahlqvist, Géraldine, Jadoul, Michel, UCL - SSS/IREC/NEFR - Pôle de Néphrologie, UCL - (SLuc) Service de néphrologie, UCL - (SLuc) Service de radiologie, UCL - (SLuc) Service de gastro-entérologie, UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, Gillion, Valentine, Dragean, Cristina, Dahlqvist, Géraldine, and Jadoul, Michel

Abstract

A 41-year-old Congolese woman born in 1977 presented in February 2018 to our emergency department with severe abdominal pain. Her medical history was notable for idiopathic collapsing glomerulopathy for which she was being initially treated with corticosteroids, later switched to tacrolimus. Additionally she was on candesartan 16 mg/d, then later switched in 2014 to enalapril 20 mg/d. During 2017, she was poorly compliant with her medications. In February 2018, her medications included tacrolimus, furosemide, spironolactone, lercanidipine, and enalapril. [...]

Published
2019

36. Virtual unenhanced phase with spectral dual-energy CT: Is it an alternative to conventional true unenhanced phase for abdominal tissues?

Author

UCL - SSS/IREC/IMAG - Pôle d'imagerie médicale, UCL - (SLuc) Service de radiologie, UCL - SSS/IONS/NEUR - Clinical Neuroscience, Jamali, Sanaa, Michoux, Nicolas, Coche, Emmanuel, Dragean, Cristina, UCL - SSS/IREC/IMAG - Pôle d'imagerie médicale, UCL - (SLuc) Service de radiologie, UCL - SSS/IONS/NEUR - Clinical Neuroscience, Jamali, Sanaa, Michoux, Nicolas, Coche, Emmanuel, and Dragean, Cristina

Abstract

PURPOSE: To compare attenuation measurements and image quality of virtual unenhanced phase (VUP) images with those of conventional true unenhanced phase (TUP) images on spectral dual energy computed tomography (DECT) with dual layer detector on abdominal tissues and to assess potential reduction in radiation dose. MATERIAL AND METHOD: A total of 295 patients (185 men, 110 women; mean age 61±17.6 [SD] years [range: 17-95 years]) who had undergone abdominal or thoraco-abdominal CT with pre- and post-contrast imaging (portal phase) with spectral DECT with dual layer detector were retrospectively analyzed. VUP images based on portal-venous phase DECT acquisition were generated. Regions of interest were defined in abdominal tissues (liver, spleen, kidney, muscle and fat) by two independent readers. Inter-technique agreement (VUP images vs. TUP images) on attenuation measurements was assessed. Signal-to noise ratio (SNR) and image quality of TUP and VUP images were compared. The radiation dose delivered to patients was compared with the radiation dose of protocols without TUP images. RESULTS: A total of 9880 ROIs were drawn in the abdominal tissues. The difference in mean attenuation values between TUP and VUP images was less than 15 HU in 98.3% and less than 10 HU in 92.3% of all measurements. VUP images overestimated attenuation in fat comparatively to TUP images. Image quality was evaluated as good or excellent in 77% (37/48) of TUP images and 54% (26/48) of VUP images. Using VUP images instead of TUP images could decrease the radiation dose by 32%. CONCLUSION: VUP images demonstrate good agreement with TUP images in different abdominals tissues and can be obtained with similar image quality as TUP. VUP images appear as an alternative to TUP images, resulting in reduction of radiation dose delivered to the patient.

Published
2019

37. Lymph node ratio and surgical quality are strong prognostic factors of rectal cancer: results from a single referral centre

Author

Alex Kartheuser, Etienne Danse, Daniel Léonard, A Medina Benites, M. Van den Eynde, Yves Humblet, N. Abbes Orabi, Anne Jouret-Mourin, Daphné Debetancourt, A. van Maanen, C. Remue, JC De Schoutheete, Ch Sempoux, F. Maddalena, A Dragean, and Pierre Scalliet

Subjects
Male, Oncology, medicine.medical_specialty, Multivariate analysis, Databases, Factual, Colorectal cancer, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Humans, Medicine, Mesentery, Elective surgery, Lymph node, Digestive System Surgical Procedures, Aged, Neoplasm Staging, Quality of Health Care, Retrospective Studies, Rectal Neoplasms, business.industry, Rectum, Gastroenterology, Middle Aged, Prognosis, medicine.disease, Survival Analysis, Total mesorectal excision, Acs nsqip, medicine.anatomical_structure, Elective Surgical Procedures, 030220 oncology & carcinogenesis, Referral centre, Lymph Node Excision, Female, 030211 gastroenterology & hepatology, Lymph Nodes, Lymph, business
Abstract

AIM Nodal stage is a strong prognostic factor of oncological outcome of rectal cancer. To compensate for the variation in total number of harvested nodes, calculation of the lymph node ratio (LNR) has been advocated. The aim of the study was to compare the impact, on the long-term oncological outcome, of the LNR with other predictive factors, including the quality of total mesorectal excision (TME) and the state of the circumferential resection margin. METHOD Consecutive patients having elective surgery for nonmetastatic rectal cancer were extracted from a prospectively maintained database. Retrospective uni- and multivariate analyses were performed based on patient-, surgical- and tumour-related factors. The prognostic value of the LNR on overall survival (OS) and on overall recurrence-free survival (ORFS) was assessed and a cut-off value was determined. RESULTS From 1998 to 2013, out of 456 patients, 357 with nonmetastatic disease were operated on for rectal cancer. Neoadjuvant radiochemotherapy was administered to 66.7% of the patients. The mean number of lymph nodes retrieved was 12.8 ± 8.78 per surgical specimen. A lower lymph node yield was obtained in patients who received neoadjuvant chemoradiotherapy (11.8 vs 14.2; P = 0.014). The 5-year ORFS was 71.8% and the 5-year OS was 80.1%. Multivariate analysis confirmed LNR, the quality of TME and age to be independent prognostic factors of OS. LNR, age and perineural infiltration were independently associated with ORFS. Low- and high-risk patients could be discriminated using an LNR cut-off value of 0.2. CONCLUSION LNR is an independent prognostic factor of OS and ORFS. In line with the principles of optimal surgical management, the quality of TME and lymph node yield are essential technical requirements.

Published
2016
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41. Comprehensive Intrametastatic Immune Quantification and Major Impact of Immunoscore on Survival.

Author

UCL - (SLuc) Service d'anatomie pathologique, Mlecnik, Bernhard, Van den Eynde, Marc, Bindea, Gabriela, Church, Sarah E, Vasaturo, Angela, Fredriksen, Tessa, Lafontaine, Lucie, Haicheur, Nacilla, Marliot, Florence, Debetancourt, Daphné, Pairet, Géraldine, Mourin, Anne, Gigot, Jean-Francois, Hubert, Catherine, Danse, Etienne, Dragean, Cristina, Carrasco, Javier, Humblet, Yves, Valge-Archer, Viia, Berger, Anne, Pagès, Franck, Machiels, Jean-Pascal, Galon, Jérôme, UCL - (SLuc) Service d'anatomie pathologique, Mlecnik, Bernhard, Van den Eynde, Marc, Bindea, Gabriela, Church, Sarah E, Vasaturo, Angela, Fredriksen, Tessa, Lafontaine, Lucie, Haicheur, Nacilla, Marliot, Florence, Debetancourt, Daphné, Pairet, Géraldine, Mourin, Anne, Gigot, Jean-Francois, Hubert, Catherine, Danse, Etienne, Dragean, Cristina, Carrasco, Javier, Humblet, Yves, Valge-Archer, Viia, Berger, Anne, Pagès, Franck, Machiels, Jean-Pascal, and Galon, Jérôme

Abstract

This study assesses how the metastatic immune landscape is impacting the response to treatment and the outcome of colorectal cancer (CRC) patients. Complete curative resection of metastases (n = 441) was performed for two patient cohorts (n = 153). Immune densities were quantified in the center and invasive margin of all metastases. Immunoscore and T and B cell (TB) score were analyzed in relation to radiological and pathological responses and patient's disease-free (DFS) and overall survival (OS) using multivariable Cox proportional hazards models. All statistical tests were two-sided. The spatial distribution of immune cells within metastases was nonuniform. Patients, as well as metastases of the same patient, had variable immune infiltrates and response to therapy. A beneficial response was statistically significantly associated with increased immune densities. Among all metastases, Immunoscore (I) and TB score evaluated in the least immune-infiltrated metastases were the strongest predictors for DFS and OS (five-year follow-up, Immunoscore: I 3-4: DFS rate = 27.9%, 95% CI = 15.2 to 51.3; vs I 0-1-2: DFS rate = 12.3%, 95% CI = 4.9 to 30.6; HR = 0.45, 95% CI = 0.28 to 0.70, P = .02; I 3-4: OS rate = 64.6%, 95% CI = 46.6 to 89.6; vs I 0-1-2: OS rate = 32.5%, 95% CI = 17.2 to 61.4; HR = 0.32, 95% CI = 0.15 to 0.66, P = .001, C-index = 65.9%; five-year follow-up, TB score: TB 3-4: DFS rate = 25.7%, 95% CI = 14.2 to 46.6; vs TB 0-1-2: DFS rate = 5.0%, 95% CI = 0.8 to 32.4; HR = 0.36, 95% CI = 0.22 to 0.57, P < .001; TB 3-4: OS rate = 63.7%, 95% CI = 46.4 to 87.5; vs TB 0-1-2: OS rate: 21.4%, 95% CI = 9.2 to 49.8; HR = 0.25, 95% CI = 0.12 to 0.51, P < .001, C-index = 67.8%). High TB score and Immunoscore patients had a median survival of 70.5 months, while low patients survived only 25.1 to 38.3 months. Nonresponding patients with high-immune infiltrates had prolonged DFS (HR = 0.28, 95% CI = 0.15 to 0.52, P = .001) and OS (HR = 0.25, 95% CI = 0.1 to 0.62, P = .001). T

Published
2018

42. Long term oncological results and quality of life after HIPEC for carcinomatosis of colorectal origin

Author

UCL - SSS/IREC/CHEX - Pôle de chirgurgie expérimentale et transplantation, UCL - SSS/IREC/IMAG - Pôle d'imagerie médicale, UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - SSS/IREC/MIRO - Pôle d'imagerie moléculaire, radiothérapie et oncologie, UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - (SLuc) Service de radiologie, UCL - (SLuc) Service d'anatomie pathologique, UCL - (SLuc) Service de chirurgie et transplantation abdominale, UCL - (SLuc) Unité d'oncologie médicale, UCL - (SLuc) Service de soins intensifs, UCL - (SLuc) Centre du cancer, Barbois, Sandrine, Léonard, Daniel, Souchet, A, Remue, Christophe, Abbes Orabi, Nora, Bachmann, Radu, Van den Eynde, Marc, Wittebole, Xavier, Cotte, E, Danse, Etienne, Mourin, Anne, Dragean, Cristina, Leclercq, Gisèle, Kartheuser, Alex, Belgian Week of Gastroenterology - XXXth edition, UCL - SSS/IREC/CHEX - Pôle de chirgurgie expérimentale et transplantation, UCL - SSS/IREC/IMAG - Pôle d'imagerie médicale, UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - SSS/IREC/MIRO - Pôle d'imagerie moléculaire, radiothérapie et oncologie, UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - (SLuc) Service de radiologie, UCL - (SLuc) Service d'anatomie pathologique, UCL - (SLuc) Service de chirurgie et transplantation abdominale, UCL - (SLuc) Unité d'oncologie médicale, UCL - (SLuc) Service de soins intensifs, UCL - (SLuc) Centre du cancer, Barbois, Sandrine, Léonard, Daniel, Souchet, A, Remue, Christophe, Abbes Orabi, Nora, Bachmann, Radu, Van den Eynde, Marc, Wittebole, Xavier, Cotte, E, Danse, Etienne, Mourin, Anne, Dragean, Cristina, Leclercq, Gisèle, Kartheuser, Alex, and Belgian Week of Gastroenterology - XXXth edition

Abstract

Introduction : Peritoneal carcinomatosis (PC) of colorectal origin remains the most advanced form of colorectal cancer and is still associated with poor outcome. Cytoreducive surgery (CRS) and hyperthermic intra-peritoneal chemotherapy (HIPEC) has deeply modified patients’ prognosis. Aim : This study aims to review our results of CRS and HIPEC based on Oxaliplatin and using a closed abdomen technique as treatment of peritonela carcinomatosis of colorectal origin. Beside oncologic outcome, this study examines the long term quality of life (QoL) of patients treated by CRS and HIPEC. Methods : This is a retrospective monocentric study based on consecutive patients presenting colorectal cancer with perioneal carcinomatosis and treated by CRS and HIPEC. Demographic, operative, post-operative and pathological data have been collected. Long term oncological results have been computed and quality of life has been evaluated using the EORTC QLQ C-30 and GIQLI questionnaires. Results : Between October 2007 and December 2015, 82 patients have undergone 92 HIPEC, of which 70 patients underwent 75 CS with Oxaliplatin HIPEC using a closed abdomen technique. Among the 38 patients alive at the time of the study, 34 had not benefited from a redo-HIPEC after December 31, 2015.Of the 82 patients operated between October 2007 and December 2015, 10 (10.9%) received prophylactic HIPEC. There were 44 women and 38 men with a median age of 60 (18-77). Twenty-one patients (32.6%) had synchronous resecable liver metastases. The median level of carcinoembryonic antigen was 2,7 ng / mL. The CC-0 and CC-1 resection scores were obtained for 75 (87.2%) and 10 (11.6%) procedures, respectively. The median index of peritoneal carcinomatosis (PCI) was 6 (0 to 30). Twenty-two patients (23.9%) had a Dindo-Clavien complication> 2 and the postoperative mortality was 1,6%. The median follow-up time is 35 months. Twenty-seven patients (29.3%) received neoadjuvant chemotherapy and 48 (53.3%) received adjuvant

Published
2018

43. Spontaneous perforation of meckel’s diverticulum [Perforation spontanée d’un diverticule de Meckel]

Author

Nurcan Yilmaz, Léonard, Daniel, Abbes Orabi, Nora, Remue Christophe, Annet, Laurence, Dragean, Cristina, Penaloza Andrea, Raptis Alexandros, Kartheuser, Alex, UCL - (SLuc) Centre du cancer, UCL - SSS/IREC/CHEX - Pôle de chirgurgie expérimentale et transplantation, UCL - (SLuc) Service de chirurgie et transplantation abdominale, UCL - SSS/IREC/IMAG - Pôle d'imagerie médicale, UCL - (SLuc) Service de radiologie, UCL - SSS/IREC/EPID - Pôle d'épidémiologie et biostatistique, and UCL - (SLuc) Service des urgences

Abstract

Un patient âgé de 39 ans consulte pour de la fièvre accompagnée d’une douleur péri-ombilicale. Le scanner abdominal permet de poser le diagnostic d’un diverticule de Meckel inflammatoire. Le traitement consiste en une diverticulectomie par laparotomie au cours de laquelle une perforation est constatée. Actuellement, il n’existe aucun consensus sur la technique radiologique à utiliser pour poser le diagnostic de cette pathologie. Le traitement est toujours chirurgical. Il n’y a pas d’accord quant à la technique opératoire à privilégier entre une diverticulectomie et une résection du segment intestinal comprenant le diverticule. De plus, le débat persiste sur la voie d’abord à entreprendre même si l’approche la moins invasive est à favoriser.

Published
2017

44. T-cell infiltration assessed in pretherapeutic biopsies of patients with locally advanced rectal adenocarcinoma (LARC) is associated with tumor response and relapse after chemoradiotherapy (CRT) and rectal surgery

Author

UCL - SSS/IREC/IMAG - Pôle d'imagerie médicale, UCL - SSS/IREC/CHEX - Pôle de chirgurgie expérimentale et transplantation, UCL - SSS/IREC/MIRO - Pôle d'imagerie moléculaire, radiothérapie et oncologie, UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - (SLuc) Service de radiologie, UCL - (SLuc) Service de gastro-entérologie, UCL - (SLuc) Service de chirurgie et transplantation abdominale, UCL - (SLuc) Service d'anatomie pathologique, UCL - (SLuc) Service de radiothérapie oncologique, UCL - (SLuc) Unité d'oncologie médicale, UCL - (SLuc) Centre du cancer, Van den Eynde, Marc, Kirilovsky, Amos, El Sissy, Carine, Marliot, Florence, Haicheur, Nacilla, Dragean, Cristina, Danse, Etienne, Denis, Marie Armelle, Kartheuser, Alex, Remue, Christophe, Léonard, Daniel, Bachmann, Radu, Baldin, Paméla, Humblet, Yves, Scalliet, Pierre, Mourin, Anne, Pages, Franck, Belgian Week of Gastroenterology - XXIXth edition, UCL - SSS/IREC/IMAG - Pôle d'imagerie médicale, UCL - SSS/IREC/CHEX - Pôle de chirgurgie expérimentale et transplantation, UCL - SSS/IREC/MIRO - Pôle d'imagerie moléculaire, radiothérapie et oncologie, UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - (SLuc) Service de radiologie, UCL - (SLuc) Service de gastro-entérologie, UCL - (SLuc) Service de chirurgie et transplantation abdominale, UCL - (SLuc) Service d'anatomie pathologique, UCL - (SLuc) Service de radiothérapie oncologique, UCL - (SLuc) Unité d'oncologie médicale, UCL - (SLuc) Centre du cancer, Van den Eynde, Marc, Kirilovsky, Amos, El Sissy, Carine, Marliot, Florence, Haicheur, Nacilla, Dragean, Cristina, Danse, Etienne, Denis, Marie Armelle, Kartheuser, Alex, Remue, Christophe, Léonard, Daniel, Bachmann, Radu, Baldin, Paméla, Humblet, Yves, Scalliet, Pierre, Mourin, Anne, Pages, Franck, and Belgian Week of Gastroenterology - XXIXth edition

Published
2017

45. Cytoreductive surgery and hyperthermic intraperitoneal chemoetherapy for peritoneal carcinomatosis from colorectal cancer: results of the association of the closed abdomen technique combined with oxaliplatin

Author

UCL - SSS/IREC/MIRO - Pôle d'imagerie moléculaire, radiothérapie et oncologie, UCL - SSS/IREC/IMAG - Pôle d'imagerie médicale, UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - SSS/IREC/CHEX - Pôle de chirgurgie expérimentale et transplantation, UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - (SLuc) Service de chirurgie et transplantation abdominale, UCL - (SLuc) Unité d'oncologie médicale, UCL - (SLuc) Service d'anatomie pathologique, UCL - (SLuc) Service de soins intensifs, UCL - SSS/IONS/CEMO - Pôle Cellulaire et moléculaire, UCL - (SLuc) Service d'anesthésiologie, UCL - (SLuc) Service de radiologie, UCL - (SLuc) Centre du cancer, Barbois, Sandrine, Léonard, Daniel, Cotte, Eddy, Van den Broeck, S., Remue, Christophe, Bachmann, Radu, Abbes Orabi, Nora, Lois, Fernande, Forget, Patrice, De Kock, Marc, Laterre, Pierre-François, Wittebole, Xavier, Humblet, Yves, Van den Eynde, Marc, Danse, Etienne, Dragean, Cristina, Mourin, Anne, Leclercq, Gisèle, Van Maanen, Aline, Kartheuser, Alex, 12th Scientific and Annual Meeting of the European Society of Coloproctology, UCL - SSS/IREC/MIRO - Pôle d'imagerie moléculaire, radiothérapie et oncologie, UCL - SSS/IREC/IMAG - Pôle d'imagerie médicale, UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - SSS/IREC/CHEX - Pôle de chirgurgie expérimentale et transplantation, UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - (SLuc) Service de chirurgie et transplantation abdominale, UCL - (SLuc) Unité d'oncologie médicale, UCL - (SLuc) Service d'anatomie pathologique, UCL - (SLuc) Service de soins intensifs, UCL - SSS/IONS/CEMO - Pôle Cellulaire et moléculaire, UCL - (SLuc) Service d'anesthésiologie, UCL - (SLuc) Service de radiologie, UCL - (SLuc) Centre du cancer, Barbois, Sandrine, Léonard, Daniel, Cotte, Eddy, Van den Broeck, S., Remue, Christophe, Bachmann, Radu, Abbes Orabi, Nora, Lois, Fernande, Forget, Patrice, De Kock, Marc, Laterre, Pierre-François, Wittebole, Xavier, Humblet, Yves, Van den Eynde, Marc, Danse, Etienne, Dragean, Cristina, Mourin, Anne, Leclercq, Gisèle, Van Maanen, Aline, Kartheuser, Alex, and 12th Scientific and Annual Meeting of the European Society of Coloproctology

Published
2017

46. Association of T-cell infiltration assessed in pretherapeutic biopsies (PTB) of patients with locally advanced rectal adenocarcinoma (LARC) with tumor response and relapse after chemoradiotherapy (CRT) and rectal surgery

Author

UCL - SSS/IREC/IMAG - Pôle d'imagerie médicale, UCL - SSS/IREC/CHEX - Pôle de chirgurgie expérimentale et transplantation, UCL - SSS/IREC/MIRO - Pôle d'imagerie moléculaire, radiothérapie et oncologie, UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - (SLuc) Service de radiologie, UCL - (SLuc) Service de gastro-entérologie, UCL - (SLuc) Service de chirurgie et transplantation abdominale, UCL - (SLuc) Service d'anatomie pathologique, UCL - (SLuc) Unité d'oncologie médicale, UCL - (SLuc) Service de radiothérapie oncologique, UCL - (SLuc) Centre du cancer, Van den Eynde, Marc, El Sissy, Carine, Kirilovsky, Amos, Marliot, Florence, Haicheur, Nacilla, Dragean, Cristina, Danse, Etienne, Denis, Marie Armelle, Kartheuser, Alex, Remue, Christophe, Léonard, Daniel, Bachmann, Radu, Baldin, Paméla, De Cuyper, Astrid, Humblet, Yves, Scalliet, Pierre, Mourin, Anne, Galon, Jerome, Pages, Franck, 2017 ASCO Annual Meeting, UCL - SSS/IREC/IMAG - Pôle d'imagerie médicale, UCL - SSS/IREC/CHEX - Pôle de chirgurgie expérimentale et transplantation, UCL - SSS/IREC/MIRO - Pôle d'imagerie moléculaire, radiothérapie et oncologie, UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - (SLuc) Service de radiologie, UCL - (SLuc) Service de gastro-entérologie, UCL - (SLuc) Service de chirurgie et transplantation abdominale, UCL - (SLuc) Service d'anatomie pathologique, UCL - (SLuc) Unité d'oncologie médicale, UCL - (SLuc) Service de radiothérapie oncologique, UCL - (SLuc) Centre du cancer, Van den Eynde, Marc, El Sissy, Carine, Kirilovsky, Amos, Marliot, Florence, Haicheur, Nacilla, Dragean, Cristina, Danse, Etienne, Denis, Marie Armelle, Kartheuser, Alex, Remue, Christophe, Léonard, Daniel, Bachmann, Radu, Baldin, Paméla, De Cuyper, Astrid, Humblet, Yves, Scalliet, Pierre, Mourin, Anne, Galon, Jerome, Pages, Franck, and 2017 ASCO Annual Meeting

Abstract

Background: Pre-operative CRT followed by total mesorectal excision (TME) is nowadays the standard of care for patient with LARC (cT3-T4N0 or cTxN+). Currently, pathologic complete response occurs in +/- 15% after CRT. Colorectal cancer T-cell infiltration is a strong prognostic factor for survival after primary tumor resection. Our aim was to determine whether T-cell infiltration in PTB could be predictive of tumor response and relapse after CRT + TME. Methods: Between 1999 and 2012, patients with LARC who underwent CRT + TME and with available clinical follow-up and PTB (with sufficient tumor cells density) were identified at the Cliniques universitaires St-Luc. The density of CD3 (T cells) and CD8 (cytotoxic) was quantified on immunostained PTB slides and analyzed with a dedicated image analysis software on whole-slide imaging. Comparisons were made using the Wilcoxon-Mann-Whitney test. Cumulative disease-free survival (DFS) was performed using the Kaplan-Meier estimator and compared by log-rank tests. Cox regression we used for uni- and multi-variate analysis. P value of less than 0.05 was considered statistically significant. Results: 154 patients (sex ratio M/F 1.8; mean age 65 years-old; upper (20%), mid (29%) and low rectum (51%), synchronous metastases (11%)) were analyzed. High CD3 and CD8 PTB densities were significantly associated with a higher pathological response (Dworak 3-4) and lower ypTNM stage after CRT +TME (p < 0,05). Higher CD3 and CD8 PTB densities were associated with higher patient DFS (CD3: HR = 2,30 (CI95%:1,15-4,59) p = 0,02; CD8: HR = 1,95 (CI95%: 1,01-3,75) p = 0,04). These results were confirmed in uni and multivariate analysis. CD3 and CD8 PTB densities added to pathological response (ypTNM/Dworak) but also clinical response (ycTNM) after CRT + TME increases significantly the accuracy prediction of tumor relapse. Conclusions: Pretherapeutic T-cell infiltration of LARC is predictive of tumor response and relapse after CRT +TME. This bi

Published
2017

47. Spontaneous perforation of meckel’s diverticulum [Perforation spontanée d’un diverticule de Meckel]

Author

UCL - (SLuc) Centre du cancer, UCL - SSS/IREC/CHEX - Pôle de chirgurgie expérimentale et transplantation, UCL - (SLuc) Service de chirurgie et transplantation abdominale, UCL - SSS/IREC/IMAG - Pôle d'imagerie médicale, UCL - (SLuc) Service de radiologie, UCL - SSS/IREC/EPID - Pôle d'épidémiologie et biostatistique, UCL - (SLuc) Service des urgences, Nurcan Yilmaz, Léonard, Daniel, Abbes Orabi, Nora, Remue Christophe, Annet, Laurence, Dragean, Cristina, Penaloza Andrea, Raptis Alexandros, Kartheuser, Alex, UCL - (SLuc) Centre du cancer, UCL - SSS/IREC/CHEX - Pôle de chirgurgie expérimentale et transplantation, UCL - (SLuc) Service de chirurgie et transplantation abdominale, UCL - SSS/IREC/IMAG - Pôle d'imagerie médicale, UCL - (SLuc) Service de radiologie, UCL - SSS/IREC/EPID - Pôle d'épidémiologie et biostatistique, UCL - (SLuc) Service des urgences, Nurcan Yilmaz, Léonard, Daniel, Abbes Orabi, Nora, Remue Christophe, Annet, Laurence, Dragean, Cristina, Penaloza Andrea, Raptis Alexandros, and Kartheuser, Alex

Abstract

Un patient âgé de 39 ans consulte pour de la fièvre accompagnée d’une douleur péri-ombilicale. Le scanner abdominal permet de poser le diagnostic d’un diverticule de Meckel inflammatoire. Le traitement consiste en une diverticulectomie par laparotomie au cours de laquelle une perforation est constatée. Actuellement, il n’existe aucun consensus sur la technique radiologique à utiliser pour poser le diagnostic de cette pathologie. Le traitement est toujours chirurgical. Il n’y a pas d’accord quant à la technique opératoire à privilégier entre une diverticulectomie et une résection du segment intestinal comprenant le diverticule. De plus, le débat persiste sur la voie d’abord à entreprendre même si l’approche la moins invasive est à favoriser.

Published
2017

48. Preoperative staging with Magnetic Resonance Imaging (MRI) and EndoRectal Ultra-sonography (ERUS) for locally advanced rectal cancer (LARC) after chemoradiotherapy (CRT): accuracy with histopathologic findings

Author

Kouinche, Nathalie, van Maanen, Aline, Dragean, Cristina, Danse, Etienne, Denis, Marie Armelle, Kartheuser, Alex, Remue, Christophe, Léonard, Daniel, Baldin, Paméla, Humblet, Yves, Scalliet, Pierre, Mourin, Anne, Van den Eynde, Marc, Belgian Week of Gastroenterology - XXVIIIth edition, UCL - SSS/IREC/IMAG - Pôle d'imagerie médicale, UCL - SSS/IREC/MIRO - Pôle d'imagerie moléculaire, radiothérapie et oncologie, UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - (SLuc) Service d'anatomie pathologique, UCL - (SLuc) Service de gastro-entérologie, UCL - (SLuc) Service de radiologie, UCL - (SLuc) Unité d'oncologie médicale, UCL - (SLuc) Service de radiothérapie oncologique, and UCL - (SLuc) Centre du cancer

Published
2016

49. Affections du côlon en situation d’urgence et en réanimation chez le patient adulte : qu’attendre du radiologue ?

Author

A. Dragean and E. Danse

Subjects
Gynecology, medicine.medical_specialty, business.industry, Emergency Medicine, medicine, Emergency Nursing, business
Abstract

L’objectif de cet article est de donner un etat des lieux des reponses actuelles du radiologue aux questions que les urgentistes et reanimateurs se posent dans leur vie quotidienne, lorsqu’une atteinte colique est suspectee chez un patient adulte. Les techniques radiologiques seront presentees, avec ce qu’elles peuvent apporter dans quelques situations cliniques usuelles telles qu’une colite infectieuse, une colite inflammatoire, une colite ischemique et les situations postoperatoires intestinales, en particulier les dehiscences de suture.

Published
2011
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50. Right Ventricle Function Assessment by MDCT

Author

Michaël Dupont, Emmanuel Coche, and Cristina Dragean

Subjects
Diagnostic Imaging, Cardiac function curve, medicine.medical_specialty, Ventricular Dysfunction, Right, Electrocardiography, Internal medicine, medicine, Medical imaging, Humans, Radiology, Nuclear Medicine and imaging, cardiovascular diseases, medicine.diagnostic_test, Normal anatomy, business.industry, General Medicine, medicine.disease, Right ventricular dysfunction, Structure and function, Pulmonary embolism, medicine.anatomical_structure, Ventricle, Ventricular Function, Right, cardiovascular system, Cardiology, Radiographic Image Interpretation, Computer-Assisted, Radiology, Tomography, X-Ray Computed, business
Abstract

OBJECTIVE: The right ventricle is often overlooked on chest and even cardiac MDCT studies. This article will review the normal anatomy of the right ventricle on MDCT and the signs of its functional alterations. CONCLUSION: MDCT signs of right ventricular dysfunction should be known and checked in relevant cases, such as pulmonary embolism in particular, and in any disease that affects both the structure and function of the lungs in general.

Published
2011
Full Text
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