Author: "A Di Ludovico" - Searchworks@Jio Institute Digital Library Search Results

Your search keyword '"A Di Ludovico"' showing total 1,429 results

Start Over Author "A Di Ludovico"

1,429 results on '"A Di Ludovico"'

1. Benchmarking the design of the cryogenics system for the underground argon in DarkSide-20k

Author: Collaboration, DarkSide-20k, Acerbi, F., Adhikari, P., Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Amaudruz, P., Angiolilli, M., Aprile, E., Ardito, R., Corona, M. Atzori, Auty, D. J., Ave, M., Avetisov, I. C., Azzolini, O., Back, H. O., Balmforth, Z., Olmedo, A. Barrado, Barrillon, P., Batignani, G., Bhowmick, P., Blua, S., Bocci, V., Bonivento, W., Bottino, B., Boulay, M. G., Buchowicz, A., Bussino, S., Busto, J., Cadeddu, M., Cadoni, M., Calabrese, R., Camillo, V., Caminata, A., Canci, N., Capra, A., Caravati, M., Cárdenas-Montes, M., Cargioli, N., Carlini, M., Castellani, A., Castello, P., Cavalcante, P., Cebrian, S., Ruiz, J. Cela, Chashin, S., Chepurnov, A., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Coadou, Y., Cocco, V., Colaiuda, D., Vilda, E. Conde, Consiglio, L., Costa, B. S., Czubak, M., D'Aniello, M., D'Auria, S., Rolo, M. D. Da Rocha, Darbo, G., Davini, S., De Cecco, S., De Guido, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Ludovico, A., Di Noto, L., Di Stefano, P., Dias, L. K., Mairena, D. Díaz, Ding, X., Dionisi, C., Dolganov, G., Dordei, F., Dronik, V., Elersich, A., Ellingwood, E., Erjavec, T., Diaz, M. Fernandez, Ficorella, A., Fiorillo, G., Franchini, P., Franco, D., Gatti, H. Frandini, Frolov, E., Gabriele, F., Gahan, D., Galbiati, C., Galiński, G., Gallina, G., Gallus, G., Garbini, M., Abia, P. Garcia, Gawdzik, A., Gendotti, A., Ghisi, A., Giovanetti, G. K., Casanueva, V. Goicoechea, Gola, A., Grandi, L., Grauso, G., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A., Hamer, A., Haranczyk, M., Harrop, B., Hessel, T., Hill, S., Horikawa, S., Hu, J., Hubaut, F., Hucker, J., Hugues, T., Hungerford, E. V., Ianni, A., Ippolito, V., Jamil, A., Jillings, C., Jois, S., Kachru, P., Keloth, R., Kemmerich, N., Kemp, A., Kendziora, C. L., Kimura, M., Kish, A., Kondo, K., Korga, G., Kotsiopoulou, L., Koulosousas, S., Kubankin, A., Kunzé, P., Kuss, M., Kuźniak, M., Kuzwa, M., La Commara, M., Lai, M., Guirriec, E. Le, Leason, E., Leoni, A., Lidey, L., Lissia, M., Luzzi, L., Lychagina, O., Macfadyen, O., Machulin, I. N., Manecki, S., Manthos, I., Mapelli, L., Marasciulli, A., Mari, S. M., Mariani, C., Maricic, J., Martinez, M., Martoff, C. J., Matteucci, G., Mavrokoridis, K., McDonald, A. B., Mclaughlin, J., Merzi, S., Messina, A., Milincic, R., Minutoli, S., Mitra, A., Moharana, A., Moioli, S., Monroe, J., Moretti, E., Morrocchi, M., Mroz, T., Muratova, V. N., Murphy, M., Murra, M., Muscas, C., Musico, P., Nania, R., Nessi, M., Nieradka, G., Nikolopoulos, K., Nikoloudaki, E., Nowak, J., Olchanski, K., Oleinik, A., Oleynikov, V., Organtini, P., de Solórzano, A. Ortiz, Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Papi, D., Pastuszak, G., Paternoster, G., Peck, A., Pegoraro, P. A., Pelczar, K., Pellegrini, L. A., Perez, R., Perotti, F., Pesudo, V., Piacentini, S. I., Pino, N., Plante, G., Pocar, A., Poehlmann, M., Pordes, S., Pralavorio, P., Price, D., Puglia, S., Bazetto, M. Queiroga, Ragusa, F., Ramachers, Y., Ramirez, A., Ravinthiran, S., Razeti, M., Renshaw, A. L., Rescigno, M., Retiere, F., Rignanese, L. P., Rivetti, A., Roberts, A., Roberts, C., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Rudik, D., Sabia, M., Salomone, P., Samoylov, O., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Santos, E. M., Savarese, C., Scapparone, E., Schillaci, G., Schuckman II, F. G., Scioli, G., Semenov, D. A., Shalamova, V., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smirnova, T., Smith, B., Sotnikov, A., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Sulis, S., Sung, A., Sunny, C., Suvorov, Y., Szelc, A. M., Taborda, O., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thompson, A., Thorpe, T. N., Tonazzo, A., Torres-Lara, S., Tricomi, A., Unzhakov, E. V., Vallivilayil, T. J., Van Uffelen, M., Velazquez-Fernandez, L., Viant, T., Viel, S., Vishneva, A., Vogelaar, R. B., Vossebeld, J., Vyas, B., Wada, M., Walczak, M. B., Wang, H., Wang, Y., Westerdale, S., Williams, L., Wojaczyński, R., Wojcik, M., Wojcik, M. M., Wright, T., Xiao, X., Xie, Y., Yang, C., Yin, J., Zabihi, A., Zakhary, P., Zani, A., Zhang, Y., Zhu, T., Zichichi, A., Zuzel, G., and Zykova, M. P.
Subjects: Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract: DarkSide-20k (DS-20k) is a dark matter detection experiment under construction at the Laboratori Nazionali del Gran Sasso (LNGS) in Italy. It utilises ~100 t of low radioactivity argon from an underground source (UAr) in its inner detector, with half serving as target in a dual-phase time projection chamber (TPC). The UAr cryogenics system must maintain stable thermodynamic conditions throughout the experiment's lifetime of over 10 years. Continuous removal of impurities and radon from the UAr is essential for maximising signal yield and mitigating background. We are developing an efficient and powerful cryogenics system with a gas purification loop with a target circulation rate of 1000 slpm. Central to its design is a condenser operated with liquid nitrogen which is paired with a gas heat exchanger cascade, delivering a combined cooling power of more than 8 kW. Here we present the design choices in view of the DS-20k requirements, in particular the condenser's working principle and the cooling control, and we show test results obtained with a dedicated benchmarking platform at CERN and LNGS. We find that the thermal efficiency of the recirculation loop, defined in terms of nitrogen consumption per argon flow rate, is 95 % and the pressure in the test cryostat can be maintained within $\pm$(0.1-0.2) mbar. We further detail a 5-day cool-down procedure of the test cryostat, maintaining a cooling rate typically within -2 K/h, as required for the DS-20k inner detector. Additionally, we assess the circuit's flow resistance, and the heat transfer capabilities of two heat exchanger geometries for argon phase change, used to provide gas for recirculation. We conclude by discussing how our findings influence the finalisation of the system design, including necessary modifications to meet requirements and ongoing testing activities., Comment: 44 pages, 25 figures, 1 table. Updated to match the published journal version
Published: 2024
Full Text: View/download PDF

2. DarkSide-20k sensitivity to light dark matter particles

Author: Collaboration, DarkSide-20k, Acerbi, F., Adhikari, P., Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Amaudruz, P., Angiolilli, M., Aprile, E., Ardito, R., Corona, M. Atzori, Auty, D. J., Ave, M., Avetisov, I. C., Azzolini, O., Back, H. O., Balmforth, Z., Olmedo, A. Barrado, Barrillon, P., Batignani, G., Bhowmick, P., Blua, S., Bocci, V., Bonivento, W., Bottino, B., Boulay, M. G., Buchowicz, A., Bussino, S., Busto, J., Cadeddu, M., Cadoni, M., Calabrese, R., Camillo, V., Caminata, A., Canci, N., Capra, A., Caravati, M., Cárdenas-Montes, M., Cargioli, N., Carlini, M., Castellani, A., Castello, P., Cavalcante, P., Cebrian, S., Ruiz, J. M. Cela, Chashin, S., Chepurnov, A., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Coadou, Y., Cocco, V., Colaiuda, D., Vilda, E. Conde, Consiglio, L., Costa, B. S., Czubak, M., D'Aniello, M., D'Auria, S., Rolo, M. D. Da Rocha, Darbo, G., Davini, S., De Cecco, S., De Guido, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Ludovico, A., Di Noto, L., Di Stefano, P., Dias, L. K., Mairena, D. Díaz, Ding, X., Dionisi, C., Dolganov, G., Dordei, F., Dronik, V., Elersich, A., Ellingwood, E., Erjavec, T., Diaz, M. Fernandez, Ficorella, A., Fiorillo, G., Franchini, P., Franco, D., Gatti, H. Frandini, Frolov, E., Gabriele, F., Gahan, D., Galbiati, C., Galiński, G., Gallina, G., Gallus, G., Garbini, M., Abia, P. Garcia, Gawdzik, A., Gendotti, A., Ghisi, A., Giovanetti, G. K., Casanueva, V. Goicoechea, Gola, A., Grandi, L., Grauso, G., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A., Hamer, A., Haranczyk, M., Harrop, B., Hessel, T., Hill, S., Horikawa, S., Hu, J., Hubaut, F., Hucker, J., Hugues, T., Hungerford, E. V., Ianni, A., Ippolito, V., Jamil, A., Jillings, C., Jois, S., Kachru, P., Keloth, R., Kemmerich, N., Kemp, A., Kendziora, C. L., Kimura, M., Kondo, K., Korga, G., Kotsiopoulou, L., Koulosousas, S., Kubankin, A., Kunzé, P., Kuss, M., Kuźniak, M., Kuzwa, M., La Commara, M., Lai, M., Guirriec, E. Le, Leason, E., Leoni, A., Lidey, L., Lissia, M., Luzzi, L., Lychagina, O., Macfadyen, O., Machulin, I. N., Manecki, S., Manthos, I., Mapelli, L., Marasciulli, A., Mari, S. M., Mariani, C., Maricic, J., Martinez, M., Martoff, C. J., Matteucci, G., Mavrokoridis, K., McDonald, A. B., Mclaughlin, J., Merzi, S., Messina, A., Milincic, R., Minutoli, S., Mitra, A., Moioli, S., Monroe, J., Moretti, E., Morrocchi, M., Mroz, T., Muratova, V. N., Murphy, M., Murra, M., Muscas, C., Musico, P., Nania, R., Nessi, M., Nieradka, G., Nikolopoulos, K., Nikoloudaki, E., Nowak, J., Olchanski, K., Oleinik, A., Oleynikov, V., Organtini, P., de Solórzano, A. Ortiz, Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Papi, D., Pastuszak, G., Paternoster, G., Peck, A., Pegoraro, P. A., Pelczar, K., Pellegrini, L. A., Perez, R., Perotti, F., Pesudo, V., Piacentini, S., Pino, N., Plante, G., Pocar, A., Poehlmann, M., Pordes, S., Pralavorio, P., Price, D., Puglia, S., Bazetto, M. Queiroga, Ragusa, F., Ramachers, Y., Ramirez, A., Ravinthiran, S., Razeti, M., Renshaw, A. L., Rescigno, M., Retiere, F., Rignanese, L. P., Rivetti, A., Roberts, A., Roberts, C., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Rudik, D., Sabia, M., Salomone, P., Samoylov, O., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Santos, E. M., Savarese, C., Scapparone, E., Schillaci, G., Schuckman II, F. G., Scioli, G., Semenov, D. A., Shalamova, V., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smirnova, T., Smith, B., Sotnikov, A., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Sulis, S., Sung, A., Sunny, C., Suvorov, Y., Szelc, A. M., Taborda, O., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thompson, A., Tonazzo, A., Torres-Lara, S., Tricomi, A., Unzhakov, E. V., Vallivilayil, T. J., Van Uffelen, M., Velazquez-Fernandez, L., Viant, T., Viel, S., Vishneva, A., Vogelaar, R. B., Vossebeld, J., Vyas, B., Walczak, M. B., Wang, Y., Wang, H., Westerdale, S., Williams, L., Wojaczyński, R., Wojcik, M., Wojcik, M. M., Wright, T., Xie, Y., Yang, C., Yin, J., Zabihi, A., Zakhary, P., Zani, A., Zhang, Y., Zhu, T., Zichichi, A., Zuzel, G., and Zykova, M. P.
Subjects: High Energy Physics - Experiment, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: The dual-phase liquid argon time projection chamber is presently one of the leading technologies to search for dark matter particles with masses below 10 GeV/c$^2$. This was demonstrated by the DarkSide-50 experiment with approximately 50 kg of low-radioactivity liquid argon as target material. The next generation experiment DarkSide-20k, currently under construction, will use 1,000 times more argon and is expected to start operation in 2027. Based on the DarkSide-50 experience, here we assess the DarkSide-20k sensitivity to models predicting light dark matter particles, including Weakly Interacting Massive Particles (WIMPs) and sub-GeV/c$^2$ particles interacting with electrons in argon atoms. With one year of data, a sensitivity improvement to dark matter interaction cross-sections by at least one order of magnitude with respect to DarkSide-50 is expected for all these models. A sensitivity to WIMP--nucleon interaction cross-sections below $1\times10^{-42}$ cm$^2$ is achievable for WIMP masses above 800 MeV/c$^2$. With 10 years exposure, the neutrino fog can be reached for WIMP masses around 5 GeV/c$^2$., Comment: 13 pages, 4 figures, supplementary material (4 figures)
Published: 2024
Full Text: View/download PDF

3. A new hybrid gadolinium nanoparticles-loaded polymeric material for neutron detection in rare event searches

Author: Collaboration, DarkSide-20k, Acerbi, F., Adhikari, P., Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F., Alexander, T., Alton, A. K., Amaudruz, P., Angiolilli, M., Aprile, E., Ardito, R., Corona, M. Atzori, Auty, D. J., Ave, M., Avetisov, I. C., Azzolini, O., Back, H. O., Balmforth, Z., Olmedo, A. Barrado, Barrillon, P., Batignani, G., Bhowmick, P., Bocci, V., Bonivento, W., Bottino, B., Boulay, M. G., Buchowicz, A., Bussino, S., Busto, J., Cadeddu, M., Cadoni, M., Calabrese, R., Camillo, V., Caminata, A., Canci, N., Capra, A., Caravati, M., Cárdenas-Montes, M., Cargioli, N., Carlini, M., Castellani, A., Castello, P., Cavalcante, P., Cavallo, D., Cebrian, S., Ruiz, J. Cela, Chashin, S., Chepurnov, A., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Coadou, Y., Cocco, V., Colaiuda, D., Vilda, E. Conde, Consiglio, L., Costa, B. S., Czubak, M., D'Auria, S., Rolo, M. D. Da Rocha, Darbo, G., Davini, S., De Cecco, S., De Guido, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Ludovico, A., Di Noto, L., Di Stefano, P., Dias, L. K., Mairena, D. Díaz, Ding, X., Dionisi, C., Dolganov, G., Dordei, F., Dronik, V., Elersich, A., Ellingwood, E., Erjavec, T., Diaz, M. Fernandez, Ficorella, A., Fiorillo, G., Franchini, P., Franco, D., Gatti, H. Frandini, Frolov, E., Gabriele, F., Gahan, D., Galbiati, C., Galinski, G., Gallina, G., Garbini, M., Abia, P. Garcia, Gawdzik, A., Gendotti, A., Ghisi, A., Giovanetti, G. K., Casanueva, V. Goicoechea, Gola, A., Grandi, L., Grauso, G., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A., Hamer, A., Haranczyk, M., Harrop, B., Hessel, T., Hill, S., Horikawa, S., Hu, J., Hubaut, F., Hucker, J., Hugues, T., Hungerford, E. V., Ianni, A., Ippolito, V., Jamil, A., Jillings, C., Keloth, R., Kemmerich, N., Kemp, A., Kendziora, C. L., Kimura, M., Kondo, K., Korga, G., Kotsiopoulou, L., Koulosousas, S., Kubankin, A., Kuss, M., Kuzniak, M., Kuzwa, M., La Commara, M., Lai, M., Guirriec, E. Le, Leason, E., Leoni, A., Lidey, L., Lissia, M., Luzzi, L., Lychagina, O., Macfadyen, O., Machulin, I. N., Manecki, S., Manthos, I., Mapelli, L., Marasciulli, A., Mari, S. M., Mariani, C., Maricic, J., Marini, A., Martinez, M., Martoff, C. J., Matteucci, G., Mavrokoridis, K., McDonald, A. B., Mclaughlin, J., Merzi, S., Messina, A., Milincic, R., Minutoli, S., Mitra, A., Moharana, A., Moioli, S., Monroe, J., Moretti, E., Morrocchi, M., Mroz, T., Muratova, V. N., Murphy, M., Murra, M., Muscas, C., Musico, P., Nania, R., Nessi, M., Nieradka, G., Nikolopoulos, K., Nikoloudaki, E., Nowak, J., Olchanski, K., Oleinik, A., Oleynikov, V., Organtini, P., de Solórzano, A. Ortiz, Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Papi, D., Pastuszak, G., Paternoster, G., Peddis, D., Pegoraro, P. A., Pelczar, K., Pellegrini, L. A., Perez, R., Perotti, F., Pesudo, V., Piacentini, S. I., Pino, N., Plante, G., Pocar, A., Poehlmann, M., Pordes, S., Pralavorio, P., Price, D., Puglia, S., Bazetto, M. Queiroga, Ragusa, F., Ramachers, Y., Ramirez, A., Ravinthiran, S., Razeti, M., Renshaw, A. L., Rescigno, M., Retiere, F., Rignanese, L. P., Rivetti, A., Roberts, A., Roberts, C., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Rudik, D., Sabia, M., Sadashivajois, S., Salomone, P., Samoylov, O., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Santos, E. M., Savarese, C., Scapparone, E., Schillaci, G., Schuckman II, F. G., Scioli, G., Semenov, D. A., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M. D., Slimani, S., Smirnov, O., Smirnova, T., Smith, B., Sotnikov, A., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Sulis, S., Sung, A., Sunny, C., Suvorov, Y., Szelc, A. M., Taborda, O., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thompson, A., Tonazzo, A., Torres-Lara, S., Tosi, S., Tricomi, A., Unzhakov, E. V., Vallivilayil, T. J., Van Uffelen, M., Velazquez-Fernandez, L., Viant, T., Vicini, S., Viel, S., Vishneva, A., Vogelaar, R. B., Vossebeld, J., Vyas, B., Wada, M., Walczak, M. B., Wang, H., Wang, Y., Westerdale, S., Williams, L., Wojaczynski, R., Wojcik, M. M., Wojcik, M., Wright, T., Xie, Y., Yang, C., Yin, J., Zabihi, A., Zakhary, P., Zani, A., Zhang, Y., Zhu, T., Zichichi, A., Zuzel, G., and Zykova, M. P.
Subjects: Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract: Experiments aimed at direct searches for WIMP dark matter require highly effective reduction of backgrounds and control of any residual radioactive contamination. In particular, neutrons interacting with atomic nuclei represent an important class of backgrounds due to the expected similarity of a WIMP-nucleon interaction, so that such experiments often feature a dedicated neutron detector surrounding the active target volume. In the context of the development of DarkSide-20k detector at INFN Gran Sasso National Laboratory (LNGS), several R&D projects were conceived and developed for the creation of a new hybrid material rich in both hydrogen and gadolinium nuclei to be employed as an essential element of the neutron detector. Thanks to its very high cross-section for neutron capture, gadolinium is one of the most widely used elements in neutron detectors, while the hydrogen-rich material is instrumental in efficiently moderating the neutrons. In this paper results from one of the R&Ds are presented. In this effort the new hybrid material was obtained as a poly(methyl methacrylate) (PMMA) matrix, loaded with gadolinium oxide in the form of nanoparticles. We describe its realization, including all phases of design, purification, construction, characterization, and determination of mechanical properties of the new material.
Published: 2024
Full Text: View/download PDF

4. Familial Mediterranean fever in children from central-southern Italy: a multicentric retrospective cohort study

Author: La Bella, Saverio, Loconte, Roberta, Attanasi, Marina, Muselli, Mario, Di Donato, Giulia, Di Ludovico, Armando, Natale, Marco, Mastrorilli, Violetta, Giugno, Andrea, Papa, Santi, Ferrante, Rossella, Buccolini, Carlotta, Antonucci, Ivana, Chiarelli, Francesco, Necozione, Stefano, Barone, Patrizia, La Torre, Francesco, and Breda, Luciana
Published: 2024
Full Text: View/download PDF

5. Skeletal muscle as a pro- and anti-inflammatory tissue: insights from children to adults and ultrasound findings

Author: Di Ludovico, Armando, La Bella, Saverio, Ciarelli, Francesca, Chiarelli, Francesco, Breda, Luciana, and Mohn, Angelika
Published: 2024
Full Text: View/download PDF

6. Pediatric rheumatology on social media: experts ensure accuracy, public drives engagement – a comparative analysis

Author: La Bella, Saverio, Attanasi, Marina, Di Ludovico, Armando, Mainieri, Francesca, Lauriola, Federico, Silvestrini, Luisa, Ciarelli, Francesca, Osmelli, Jacopo, Girlando, Virginia, Rinaldi, Marta, Chiarelli, Francesco, Ozen, Seza, Gattorno, Marco, and Breda, Luciana
Published: 2025
Full Text: View/download PDF

7. Novel techniques for alpha/beta pulse shape discrimination in Borexino

Author: Basilico, D., Bellini, G., Benziger, J., Biondi, R., Caccianiga, B., Calaprice, F., Caminata, A., Chepurnov, A., D'Angelo, D., Derbin, A., Di Giacintov, A., Di Marcello, V., Ding, X. F., Di Ludovico, A., Di Noto, L., Drachnev, I., Franco, D., Galbiati, C., Ghiano, C., Giammarchi, M., Goretti, A., Gromov, M., Guffanti, D., Ianni, Aldo, Ianni, Andrea, Jany, A., Kobychev, V., Korga, G., Kumaran, S., Laubenstein, M., Litvinovich, E., Lombardi, P., Lomskaya, I., Ludhova, L., Machulin, I., Martyn, J., Meroni, E., Miramonti, L., Misiaszek, M., Muratova, V., Nugmanov, R., Oberauer, L., Orekhov, V., Ortica, F., Pallavicini, M., Pelicci, L., Penek, O., Pietrofaccia, L., Pilipenko, N., Pocar, A., Raikov, G., Ranalli, M. T., Ranucci, G., Razeto, A., Re, A., Rossi, N., Schoenert, S., Semenov, D., Settanta, G., Skorokhvatov, M., Singhal, A., Smirnov, O., Sotnikov, A., Tartaglia, R., Testera, G., Unzhakov, E., Vishneva, A., Vogelaar, R. B., von Feilitzsch, F., Wojcik, M., Wurm, M., Zavatarelli, S., Zuber, K., and Zuzel, G.
Subjects: High Energy Physics - Experiment, Astrophysics - Solar and Stellar Astrophysics, Physics - Instrumentation and Detectors
Abstract: Borexino could efficiently distinguish between alpha and beta radiation in its liquid scintillator by the characteristic time profile of their scintillation pulse. This alpha/beta discrimination, first demonstrated at the tonne scale in the Counting Test Facility prototype, was used throughout the lifetime of the experiment between 2007 and 2021. With this method, alpha events are identified and subtracted from the beta-like solar neutrino events. This is particularly important in liquid scintillator as alpha scintillation is quenched many-fold. In Borexino, the prominent Po-210 decay peak was a background in the energy range of electrons scattered from Be-7 solar neutrinos. Optimal alpha-beta discrimination was achieved with a "multi-layer perceptron neural network", which its higher ability to leverage the timing information of the scintillation photons detected by the photomultiplier tubes. An event-by-event, high efficiency, stable, and uniform pulse shape discrimination was essential in characterising the spatial distribution of background in the detector. This benefited most Borexino measurements, including solar neutrinos in the \pp chain and the first direct observation of the CNO cycle in the Sun. This paper presents the key milestones in alpha/beta discrimination in Borexino as a term of comparison for current and future large liquid scintillator detectors, Comment: 13 pages, 14 figures
Published: 2023
Full Text: View/download PDF

8. Perinatal outcome in anti-NMDAr encephalitis during pregnancy—a systematic review with individual patients’ data analysis

Author: Scorrano, Giovanna, Dono, Fedele, Corniello, Clarissa, Consoli, Stefano, Evangelista, Giacomo, Di Ludovico, Armando, Chiarelli, Francesco, Anzellotti, Francesca, Di Iorio, Angelo, and Sensi, Stefano L.
Published: 2024
Full Text: View/download PDF

9. Space-borne DInSAR measurements exploitation for risk classification of bridge networks

Author: Miano, Andrea, Mele, Annalisa, Silla, Michela, Bonano, Manuela, Striano, Pasquale, Lanari, Riccardo, Di Ludovico, Marco, and Prota, Andrea
Published: 2024
Full Text: View/download PDF

10. Final results of Borexino on CNO solar neutrinos

Author: Basilico, D., Bellini, G., Benziger, J., Biondi, R., Caccianiga, B., Calaprice, F., Caminata, A., Chepurnov, A., D'Angelo, D., Derbin, A., Di Giacinto, A., Di Marcello, V., Ding, X. F., Di Ludovico, A., Di Noto, L., Drachnev, I., Franco, D., Galbiati, C., Ghiano, C., Giammarchi, M., Goretti, A., Gromov, M., Guffanti, D., Ianni, Aldo, Ianni, Andrea, Jany, A., Kobychev, V., Korga, G., Kumaran, S., Laubenstein, M., Litvinovich, E., Lombardi, P., Lomskaya, I., Ludhova, L., Machulin, I., Martyn, J., Meroni, E., Miramonti, L., Misiaszek, M., Muratova, V., Nugmanov, R., Oberauer, L., Orekhov, V., Ortica, F., Pallavicini, M., Pelicci, L., Penek, Ö., Pietrofaccia, L., Pilipenko, N., Pocar, A., Raikov, G., Ranalli, M. T., Ranucci, G., Razeto, A., Re, A., Rossi, N., Schönert, S., Semenov, D., Settanta, G., Skorokhvatov, M., Singhal, A., Smirnov, O., Sotnikov, A., Tartaglia, R., Testera, G., Unzhakov, E., Villante, F. L., Vishneva, A., Vogelaar, R. B., von Feilitzsch, F., Wojcik, M., Wurm, M., Zavatarelli, S., Zuber, K., and Zuzel, G.
Subjects: High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract: We report the first measurement of CNO solar neutrinos by Borexino that uses the Correlated Integrated Directionality (CID) method, exploiting the sub-dominant Cherenkov light in the liquid scintillator detector. The directional information of the solar origin of the neutrinos is preserved by the fast Cherenkov photons from the neutrino scattered electrons, and is used to discriminate between signal and background. The directional information is independent from the spectral information on which the previous CNO solar neutrino measurements by Borexino were based. While the CNO spectral analysis could only be applied on the Phase-III dataset, the directional analysis can use the complete Borexino data taking period from 2007 to 2021. The absence of CNO neutrinos has been rejected with >5{\sigma} credible level using the Bayesian statistics. The directional CNO measurement is obtained without an external constraint on the $^{210}$Bi contamination of the liquid scintillator, which was applied in the spectral analysis approach. The final and the most precise CNO measurement of Borexino is then obtained by combining the new CID-based CNO result with an improved spectral fit of the Phase-III dataset. Including the statistical and the systematic errors, the extracted CNO interaction rate is $R(\mathrm{CNO})=6.7^{+1.2}_{-0.8} \, \mathrm{cpd/100 \, tonnes}$. Taking into account the neutrino flavor conversion, the resulting CNO neutrino flux at Earth is $\Phi_\mathrm{CNO}=6.7 ^{+1.2}_{-0.8} \times 10^8 \, \mathrm{cm^{-2} s^{-1}}$, in agreement with the high metallicity Standard Solar Models. The results described in this work reinforce the role of the event directional information in large-scale liquid scintillator detectors and open up new avenues for the next-generation liquid scintillator or hybrid neutrino experiments.
Published: 2023
Full Text: View/download PDF

11. Reliability of a generative artificial intelligence tool for pediatric familial Mediterranean fever: insights from a multicentre expert survey

Author: La Bella, Saverio, Attanasi, Marina, Porreca, Annamaria, Di Ludovico, Armando, Maggio, Maria Cristina, Gallizzi, Romina, La Torre, Francesco, Rigante, Donato, Soscia, Francesca, Ardenti Morini, Francesca, Insalaco, Antonella, Natale, Marco Francesco, Chiarelli, Francesco, Simonini, Gabriele, De Benedetti, Fabrizio, Gattorno, Marco, and Breda, Luciana
Published: 2024
Full Text: View/download PDF

12. Associations of C reactive protein to albumin ratio, neutrophil to lymphocyte ratio, platelet to lymphocyte ratio with disease activity in patients with juvenile idiopathic arthritis

Author: Di Donato, Giulia, Attanasi, Marina, Mariarita d’ Angelo, Debora, La Bella, Saverio, Di Ludovico, Armando, Chiarelli, Francesco, and Breda, Luciana
Published: 2024
Full Text: View/download PDF

13. Borexino's search for low-energy neutrinos associated with gravitational wave events from GWTC-3 database

Author: BOREXINO Collaboration, Basilico, D., Bellini, G., Benziger, J., Biondi, R., Caccianiga, B., Calaprice, F., Caminata, A., Chepurnov, A., Angelo, D. D', Derbin, A., Di Giacinto, A., Di Marcello, V., Ding, X. F., Di Ludovico, A., Di Noto, L., Drachnev, I., Franco, D., Galbiati, C., Ghiano, C., Giammarchi, M., Goretti, A., Gromov, M., Guffanti, D., Ianni, Aldo, Ianni, Andrea, Jany, A., Kobychev, V., Korga, G., Kumaran, S., Laubenstein, M., Litvinovich, E., Lombardi, P., Lomskaya, I., Ludhova, L., Machulin, I., Martyn, J., Meroni, E., Miramonti, L., Misiaszek, M., Muratova, V., Nugmanov, R., Oberauer, L., Orekhov, V., Ortica, F., Pallavicini, M., Pelicci, L., Penek, O., Pietrofaccia, L., Pilipenko, N., Pocar, A., Raikov, G., Ranalli, M. T., Ranucci, G., Razeto, A., Re, A., Rossi, N., Schonert, S., Semenov, D., Settanta, G., Skorokhvatov, M., Singhal, A., Smirnov, O., Sotnikov, A., Tartaglia, R., Testera, G., Unzhakov, E., Vishneva, A., Vogelaar, R. B., von Feilitzsch, F., Wojcik, M., Wurm, M., Zavatarelli, S., Zuber, K., and Zuzel, G.
Subjects: Astrophysics - High Energy Astrophysical Phenomena, High Energy Physics - Experiment, High Energy Physics - Phenomenology
Abstract: The search for neutrino events in correlation with gravitational wave (GW) events for three observing runs (O1, O2 and O3) from 09/2015 to 03/2020 has been performed using the Borexino data-set of the same period. We have searched for signals of neutrino-electron scattering with visible energies above 250 keV within a time window of 1000 s centered at the detection moment of a particular GW event. The search was done with three visible energy thresholds of 0.25, 0.8 and 3.0 MeV.Two types of incoming neutrino spectra were considered: the mono-energetic line and the spectrum expected from supernovae. The same spectra were considered for electron antineutrinos detected through inverse beta-decay (IBD) reaction. GW candidates originated by merging binaries of black holes (BHBH), neutron stars (NSNS) and neutron star and black hole (NSBH) were analysed separately. Additionally, the subset of most intensive BHBH mergers at closer distances and with larger radiative mass than the rest was considered. In total, follow-ups of 74 out of 93 gravitational waves reported in the GWTC-3 catalog were analyzed and no statistically significant excess over the background was observed. As a result, the strongest upper limits on GW-associated neutrino and antineutrino fluences for all flavors (\nu_e, \nu_\mu, \nu_\tau) have been obtained in the (0.5 - 5.0) MeV neutrino energy range., Comment: 13 pages, 8 figures
Published: 2023
Full Text: View/download PDF

14. How social media are changing pediatricians and pediatrics? – A claim for regulation

Author: Saverio La Bella, Armando Di Ludovico, Niccolò Parri, Antonio Di Mauro, and Antonio Corsello
Subjects: Social media, Pediatrics, Education, Children, Healthcare, Network, RJ1-570
Abstract: Abstract Background Social media has revolutionized the way healthcare professionals communicate with the public, particularly in Pediatrics. With over 5 billion users globally, platforms such as Facebook, Instagram, and TikTok have become increasingly popular even among caregivers in recent years. These channels offer unique opportunities to improve public health education, allowing pediatricians to reach a wide audience with evidence-based content. Main body However, the risks associated with misinformation pose significant challenges to health professionals and medical organizations. In response, new recommendations for the proper use of social media in pediatric health communication should be proposed, aiming to provide a network where pediatricians can collaborate, share evidence-based information, and develop effective strategies for digital communication. With the growing use of artificial intelligence in healthcare and the rise of parental self-care practices, pediatricians must actively curate and share reliable information. Conclusion This could serve as a new hub for ensuring that accurate, high-quality evidence-based information is disseminated, balancing the benefits of digital health advancements with the ethical responsibility of safeguarding patient care. By prioritizing professionalism, ethical communication, and technological adaptation, the aim should be to foster a more informed and health-conscious community.
Published: 2024
Full Text: View/download PDF

15. Status and prospects of SABRE North

Author: Mariani, A., Benziger, J. B., Calaprice, F., Copello, S., Dafinei, I., D'Angelo, D., D'Imperio, G., Di Carlo, G., Diemoz, M., Di Giacinto, A., Di Ludovico, A., Ianna, M., Ianni, A., Milana, S., Orlandi, D., Pettinacci, V., Pietrofaccia, L., Rahatlou, S., Suerfu, B., Tomei, C., Vignoli, C., and Zani, A.
Subjects: Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract: We present the characterization of a low background NaI(Tl) crystal for the SABRE North experiment. The crystal NaI-33, was studied in two different setups at Laboratori Nazionali del Gran Sasso, Italy. The Proof-of-Principle (PoP) detector was equipped with a liquid scintillator veto and collected data for about one month (90 kg$\times$days). The PoP-dry setup consisted of NaI-33 in a purely passive shielding and collected data for almost one year (891 kg$\times$days). The average background in the energy region of interest (1-6 keV) for dark matter search was 1.20 $\pm$ 0.05 and 1.39 $\pm$ 0.02 counts/day/kg/keV within the PoP and the PoP-dry setup, respectively. This result opens to a new shielding design for the physics phase of the SABRE North detector, that does not foresee the use of an organic liquid scintillator external veto., Comment: 5 pages, 2 figures. arXiv admin note: substantial text overlap with arXiv:2205.13876
Published: 2022

16. Walkability and Rebalancing of Centralities in a City Under Reconstruction

Author: Eugeni, Federico, Sacco, Sara, Di Ludovico, Donato, D’Ovidio, Gino, Tira, Maurizio, editor, Tiboni, Michela, editor, Pezzagno, Michele, editor, and Maternini, Giulio, editor
Published: 2024
Full Text: View/download PDF

17. OMA Test and Model Refinement of a Reinforced Concrete Arch Bridge

Author: Rosati, Ilenia, Reynders, Edwin P. B., Lombaert, G., Di Ludovico, Marco, Fabbrocino, Giovanni, Rainieri, Carlo, di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Cui, Zhen-Dong, Series Editor, Rainieri, Carlo, editor, Gentile, Carmelo, editor, and Aenlle López, Manuel, editor
Published: 2024
Full Text: View/download PDF

18. Structural Health Monitoring of Road Systems: From the Network Analysis to the Single Bridge Assessment

Author: Miano, Andrea, Lobianco, Alessandro Lubrano, Mele, Annalisa, Fiorillo, Antimo, Di Ludovico, Marco, Prota, Andrea, di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Cui, Zhen-Dong, Series Editor, Rainieri, Carlo, editor, Gentile, Carmelo, editor, and Aenlle López, Manuel, editor
Published: 2024
Full Text: View/download PDF

19. Urban Safety and Resilience: Agent-Based Modelling Simulations for Pre-disaster Planning

Author: Eugeni, Federico, Sacco, Sara, Di Ludovico, Donato, di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Cui, Zhen-Dong, Series Editor, Marucci, Alessandro, editor, Zullo, Francesco, editor, Fiorini, Lorena, editor, and Saganeiti, Lucia, editor
Published: 2024
Full Text: View/download PDF

20. Urban and Spatial Planning Through the Support Tool of the Regional Digital Twin

Author: Sacco, Sara, Eugeni, Federico, Di Ludovico, Donato, di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Cui, Zhen-Dong, Series Editor, Marucci, Alessandro, editor, Zullo, Francesco, editor, Fiorini, Lorena, editor, and Saganeiti, Lucia, editor
Published: 2024
Full Text: View/download PDF

21. Influence of Infill-to-Frame Connection on the Seismic Response of RC Frames

Author: Del Vecchio, Ciro, Di Ludovico, Marco, Verderame, Gerardo Mario, Prota, Andrea, di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Cui, Zhen-Dong, Series Editor, Aiello, Maria Antonietta, editor, and Bilotta, Antonio, editor
Published: 2024
Full Text: View/download PDF

22. The Pseudo-dynamic Testing Facility at UNINA: Preliminary Test on a RC Frame

Author: Del Vecchio, Ciro, Di Ludovico, Marco, Fiorillo, Antimo, Verderame, Gerardo Mario, Prota, Andrea, Manfredi, Gaetano, Cosenza, Edoardo, di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, and Menegotto, Marco, editor
Published: 2024
Full Text: View/download PDF

23. Applications of basophil activation test in paediatric allergic diseases

Author: Dodi Giulia, MD, Di Filippo Paola, MD, Di Ludovico Armando, MD, Simeone Pasquale, PhD, De Bellis Domenico, MSc, D'ascanio Francesca, MSc, Di Pillo Sabrina, MD, Chiarelli Francesco, PhD, Lanuti Paola, PhD, and Attanasi Marina, PhD
Subjects: Basophil activation test, Pediatrics, Allergic disease, Venom allergy, Spontaneous chronic urticaria, Immunologic diseases. Allergy, RC581-607
Abstract: Basophilic granulocytes, containing and releasing histamine after a specific allergy stimulation, are directly involved in IgE-mediated allergic reactions. CD63 is a transmembrane protein of secretory lysosomes of basophils and its upregulation is related with the release of histamine to the extracellular space during IgE-mediated allergic reactions. Basophil activation test (BAT) measures the activation of circulating basophils upon the in vitro stimulation of living blood cells with specific allergens. Such a test is particularly safe and reproducible and has recently emerged as a new promising diagnostic tool for allergic diseases.BAT can be used to diagnose food allergy and represents a promising alternative to oral food challenge tests, especially in children as it is less invasive, safer, and cheaper than the gold standard tests. As a biomarker of tolerance and reactivity, it is also useful to monitor natural resolution and clinical response to immune-modulatory treatments. Regarding drug allergies, BAT is even the only possible applicable diagnostic tool for allergy reactions to some drugs, because of the lack of alternative test, or given that those commonly used are unreliable, or equivocal. Additionally, BAT allows to screen patients with more active urticarial and identify Hymenoptera-allergic patients with negative venom-specific immunoglobulin (Ig)E. In respiratory allergic diseases, BAT can facilitate the diagnosis of local allergic rhinitis and evaluate basophil allergen sensitivity in allergic asthma. Although IgE-sensitization in allergic asthma is usually demonstrated by skin prick test and specific IgE, those tests do not predict the clinical allergy contribution to asthma pathogenesis. To date, the potential of BAT in the diagnostic work-up of allergic diseases is well established, but a better standardization of its use is needed. This narrative review summarizes the state-of-the-art BAT technology and applications in pediatric allergic diseases, focusing on immune-related mechanisms and the BAT real clinical utility.
Published: 2024
Full Text: View/download PDF

24. Kidney manifestations of pediatric Sjögren's syndrome

Author: La Bella, Saverio, Vivarelli, Marina, Di Ludovico, Armando, Di Donato, Giulia, Chiarelli, Francesco, and Breda, Luciana
Subjects: Renal manifestations of general diseases -- Diagnosis -- Care and treatment, Sjogren's syndrome -- Diagnosis -- Care and treatment, Immunosuppressive agents -- Dosage and administration, Health
Abstract: Approximately 1% of all patients with Sjögren's syndrome (SS) are children. Unlike the adult form, in which sicca syndrome is the main presentation, in children, the most common clinical finding is recurrent enlargement of the salivary glands. In pediatric SS, extraglandular manifestations represent a significant feature and, among these, kidney manifestations are relevant. Kidney involvement is observed in 5-20.5% of children with SS, most frequently tubulointerstitial nephritis. This injury can lead to serious phenotypes, including distal kidney tubular acidosis with the development of severe hypokalemia, which can lead to ECG abnormalities, weakness, and hypokalemic periodic paralysis. Kidney implications in pediatric SS also include nephrolithiasis, nephrocalcinosis, and various types of glomerular damage, which often require immunosuppressive therapies. Laboratory findings are usually comparable to adults, including hyperglobulinemia and high rates of antinuclear antibodies (ANA, 63.6-96.2%), and anti-Ro/SSA (36.4-84.6%). The current classification criteria for SS are inaccurate for the pediatric population, and more specific criteria are needed to improve the diagnostic rate. Due to the rarity of the disease, strong recommendations for treatment are lacking, and several therapeutic strategies have been reported, mostly based on glucocorticoids and disease-modifying antirheumatic drugs, with different outcomes. The aim of this paper is to provide an overview of the kidney implications of pediatric SS based on the latest evidence of the medical literature., Author(s): Saverio La Bella [sup.1] , Marina Vivarelli [sup.2] , Armando Di Ludovico [sup.1] , Giulia Di Donato [sup.1] , Francesco Chiarelli [sup.1] , Luciana Breda [sup.1] Author Affiliations: (1) [...]
Published: 2024
Full Text: View/download PDF

25. Seismic performance of infilled RC frames retrofitted with thermal insulation coatings

Author: Molitierno, Carmine, Del Vecchio, Ciro, Di Ludovico, Marco, and Prota, Andrea
Published: 2025
Full Text: View/download PDF

26. Improved measurement of solar neutrinos from the Carbon-Nitrogen-Oxygen cycle by Borexino and its implications for the Standard Solar Model

Author: Appel, S., Bagdasarian, Z., Basilico, D., Bellini, G., Benziger, J., Biondi, R., Caccianiga, B., Calaprice, F., Caminata, A., Cavalcante, P., Chepurnov, A., D'Angelo, D., Derbin, A., Di Giacinto, A., Di Marcello, V., Ding, X. F., Di Ludovico, A., Di Noto, L., Drachnev, I., Franco, D., Galbiati, C., Ghiano, C., Giammarchi, M., Goretti, A., Göttel, A. S., Gromov, M., Guffanti, D., Ianni, Aldo, Ianni, Andrea, Jany, A., Kobychev, V., Korga, G., Kumaran, S., Laubenstein, M., Litvinovich, E., Lombardi, P., Lomskaya, I., Ludhova, L., Lukyanchenko, G., Machulin, I., Martyn, J., Meroni, E., Miramonti, L., Misiaszek, M., Muratova, V., Nugmanov, R., Oberauer, L., Orekhov, V., Ortica, F., Pallavicini, M., Papp, L., Pelicci, L., Penek, Ö., Pietrofaccia, L., Pilipenko, N., Pocar, A., Raikov, G., Ranalli, M. T., Ranucci, G., Razeto, A., Re, A., Redchuk, M., Rossi, N., Schönert, S., Semenov, D., Settanta, G., Skorokhvatov, M., Singhal, A., Smirnov, O., Sotnikov, A., Tartaglia, R., Testera, G., Unzhakov, E., Villante, F. L., Vishneva, A., Vogelaar, R. B., von Feilitzsch, F., Wojcik, M., Wurm, M., Zavatarelli, S., Zuber, K., and Zuzel, G.
Subjects: High Energy Physics - Experiment, Astrophysics - Solar and Stellar Astrophysics
Abstract: We present an improved measurement of the CNO solar neutrino interaction rate at Earth obtained with the complete Borexino Phase-III dataset. The measured rate R$_{\rm CNO}$ = $6.7^{+2.0}_{-0.8}$ counts/(day$ \cdot$ 100 tonnes), allows us to exclude the absence of the CNO signal with about 7$\sigma$ C.L. The correspondent CNO neutrino flux is $6.6^{+2.0}_{-0.9} \times 10^8$ cm$^{-2}$ s$^{-1}$, taking into account the neutrino flavor conversion. We use the new CNO measurement to evaluate the C and N abundances in the Sun with respect to the H abundance for the first time with solar neutrinos. Our result of $N_{\rm CN}$ = $(5.78^{+1.86}_{-1.00})\times10^{-4}$ displays a $\sim$2$\sigma$ tension with the "low metallicity" spectroscopic photospheric measurements. On the other hand, our result used together with the $^7$Be and $^8$B solar neutrino fluxes, also measured by Borexino, permits to disfavour at 3.1$\sigma$ C.L. the "low metallicity" SSM B16-AGSS09met as an alternative to the "high metallicity" SSM B16-GS98., Comment: 8 pages, 6 figures
Published: 2022
Full Text: View/download PDF

27. Performance of the SABRE detector module in a purely passive shielding

Author: Calaprice, F., Benziger, J. B., Copello, S., Dafinei, I., D'Angelo, D., D'Imperio, G., Di Carlo, G., Diemoz, M., Di Giacinto, A., Di Ludovico, A., Ianna, M., Ianni, A., Mariani, A., Milana, S., Orlandi, D., Pettinacci, V., Pietrofaccia, L., Rahatlou, S., Suerfu, B., Tomei, C., Vignoli, C., and Zani, A.
Subjects: Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract: We present here a characterization of the low background NaI(Tl) crystal NaI-33 based on a period of almost one year of data taking (891 kgxdays exposure) in a detector configuration with no use of organic scintillator veto. This remarkably radio-pure crystal already showed a low background in the SABRE Proof-of-Principle (PoP) detector, in the low energy region of interest (1-6 keV) for the search of dark matter interaction via the annual modulation signature. As the vetoable background components, such as $^{40}$K, are here sub-dominant, we reassembled the PoP setup with a fully passive shielding. We upgraded the selection of events based on a Boosted Decision Tree algorithm that rejects most of the PMT-induced noise while retaining scintillation signals with > 90% efficiency in 1-6 keV. We find an average background of 1.39 $\pm$ 0.02 counts/day/kg/keV in the region of interest and a spectrum consistent with data previously acquired in the PoP setup, where the external veto background suppression was in place. Our background model indicates that the dominant background component is due to decays of $^{210}$Pb, only partly residing in the crystal itself. The other location of $^{210}$Pb is the reflector foil that wraps the crystal. We now proceed to design the experimental setup for the physics phase of the SABRE North detector, based on an array of similar crystals, using a low radioactivity PTFE reflector and further improving the passive shielding strategy, in compliance with the new safety and environmental requirements of Laboratori Nazionali del Gran Sasso., Comment: 8 pages, 9 figures
Published: 2022
Full Text: View/download PDF

28. Independent determination of the Earth's orbital parameters with solar neutrinos in Borexino

Author: Appel, S., Bagdasarian, Z., Basilico, D., Bellini, G., Benziger, J., Biondi, R., Caccianiga, B., Calaprice, F., Caminata, A., Chepurnov, A., D'Angelo, D., Derbin, A., Di Giacinto, A., Di Marcello, V., Ding, X. F., Di Ludovico, A., Di Noto, L., Drachnev, I., Franco, D., Galbiati, C., Ghiano, C., Giammarchi, M., Goretti, A., Goettel, A. S., Gromov, M., Guffanti, D., Ianni, Aldo, Ianni, Andrea, Jany, A., Kobychev, V., Korga, G., Kumaran, S., Laubenstein, M., Litvinovich, E., Lombardi, P., Lomskaya, I., Ludhova, L., Lukyanchenko, G., Machulin, I., Martyn, J., Meroni, E., Miramonti, L., Misiaszek, M., Muratova, V., Nugmanov, R., Oberauer, L., Orekhov, V., Ortica, F., Pallavicini, M., Pelicci, L., Penek, O., Pietrofaccia, L., Pilipenko, N., Pocar, A., Raikov, G., Ranalli, M. T., Ranucci, G., Razeto, A., Re, A., Redchuk, M., Rossi, N., Schoenert, S., Semenov, D., Settanta, G., Skorokhvatov, M., Singhal, A., Smirnov, O., Sotnikov, A., Tartaglia, R., Testera, G., Unzhakov, E., Vishneva, A., Vogelaar, R. B., von Feilitzsch, F., Wojcik, M., Wurm, M., Zavatarelli, S., Zuber, K., and Zuzel, G.
Subjects: High Energy Physics - Experiment, Astrophysics - Earth and Planetary Astrophysics, Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Solar and Stellar Astrophysics, High Energy Physics - Phenomenology
Abstract: Since the beginning of 2012, the Borexino collaboration has been reporting precision measurements of the solar neutrino fluxes, emitted in the proton-proton chain and in the Carbon-Nitrogen-Oxygen cycle. The experimental sensitivity achieved in Phase-II and Phase-III of the Borexino data taking made it possible to detect the annual modulation of the solar neutrino interaction rate due to the eccentricity of Earth's orbit, with a statistical significance greater than 5$\sigma$. This is the first precise measurement of the Earth's orbital parameters based solely on solar neutrinos and an additional signature of the solar origin of the Borexino signal. The complete periodogram of the time series of the Borexino solar neutrino detection rate is also reported, exploring frequencies between one cycle/year and one cycle/day. No other significant modulation frequencies are found. The present results were uniquely made possible by Borexino's decade-long high-precision solar neutrino detection., Comment: 12 pages, 10 figures
Published: 2022
Full Text: View/download PDF

29. Risk and Protective Factors for Obstructive Sleep Apnea Syndrome Throughout Lifespan: From Pregnancy to Adolescence

Author: Duilio Petrongari, Francesca Ciarelli, Paola Di Filippo, Armando Di Ludovico, Sabrina Di Pillo, Francesco Chiarelli, Giulia Maria Pellegrino, Giuseppe Francesco Sferrazza Papa, Luana Nosetti, and Marina Attanasi
Subjects: obstructive sleep apnea syndrome, obstructive sleep disorders, sleep disorders, adenotonsillar hypertrophy, obesity, children, Pediatrics, RJ1-570
Abstract: Background: Obstructive sleep apnea syndrome (OSAS) in children is indeed a significant and often underdiagnosed condition. The risk factors for OSAS vary across different stages of life. Objectives: Identifying risk factors early can help in taking preventive measures to reduce the likelihood of developing OSAS, and different life stages may require different interventions. Results: During pregnancy, maternal factors such as obesity, smoking, and genetic predispositions can increase the risk of OSAS, while breastfeeding serves as a protective factor. For children aged 2 to 12, adenotonsillar hypertrophy is the primary cause of airway narrowing, with other contributing factors including obesity, craniofacial abnormalities, and increased nasal resistance. In adolescence, obesity and craniofacial abnormalities remain the main risk factors. Conclusions: By reviewing and understanding these risk factors, healthcare providers can offer more personalized and effective care, ultimately leading to better health outcomes for individuals at all stages of life.
Published: 2025
Full Text: View/download PDF

30. National risk assessment of Italian school buildings: The MARS project experience

Author: Cattari, Serena, Alfano, Sara, Manfredi, Vincenzo, Borzi, Barbara, Faravelli, Marta, Di Meo, Antonella, da Porto, Francesca, Saler, Elisa, Dall’Asta, Andrea, Gioiella, Laura, Di Ludovico, Marco, Del Vecchio, Ciro, Del Gaudio, Carlo, Verderame, Gerardo, Gattesco, Natalino, Boem, Ingrid, Speranza, Elena, Dolce, Mauro, Lagomarsino, Sergio, and Masi, Angelo
Published: 2024
Full Text: View/download PDF

31. First Directional Measurement of sub-MeV Solar Neutrinos with Borexino

Author: Agostini, M., Altenmüller, K., Appel, S., Atroshchenko, V., Bagdasarian, Z., Basilico, D., Bellini, G., Benziger, J., Biondi, R., Bravo, D., Caccianiga, B., Calaprice, F., Caminata, A., Cavalcante, P., Chepurnov, A., D'Angelo, D., Davini, S., Derbin, A., Di Giacinto, A., Di Marcello, V., Ding, X. F., Di Ludovico, A., Di Noto, L., Drachnev, I., Formozov, A., Franco, D., Galbiati, C., Ghiano, C., Giammarchi, M., Goretti, A., Göttel, A. S., Gromov, M., Guffanti, D., Ianni, Aldo, Ianni, Andrea, Jany, A., Jeschke, D., Kobychev, V., Korga, G., Kumaran, S., Laubenstein, M., Litvinovich, E., Lombardi, P., Lomskaya, I., Ludhova, L., Lukyanchenko, G., Lukyanchenko, L., Machulin, I., Martyn, J., Meroni, E., Meyer, M., Miramonti, L., Misiaszek, M., Muratova, V., Neumair, B., Nieslony, M., Nugmanov, R., Oberauer, L., Orekhov, V., Ortica, F., Pallavicini, M., Papp, L., Pellicci, L., Penek, Ö., Pietrofaccia, L., Pilipenko, N., Pocar, A., Raikov, G., Ranalli, M. T., Ranucci, G., Razeto, A., Re, A., Redchuk, M., Romani, A., Rossi, N., Schönert, S., Semenov, D., Settanta, G., Skorokhvatov, M., Singhal, A., Smirnov, O., Sotnikov, A., Suvorov, Y., Tartaglia, R., Testera, G., Thurn, J., Unzhakov, E., Vishneva, A., Vogelaar, R. B., von Feilitzsch, F., Wessel, A., Wojcik, M., Wonsak, B., Wurm, M., Zavatarelli, S., Zuber, K., and Zuzel, G.
Subjects: High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract: We report the measurement of sub-MeV solar neutrinos through the use of their associated Cherenkov radiation, performed with the Borexino detector at the Laboratori Nazionali del Gran Sasso. The measurement is achieved using a novel technique that correlates individual photon hits of events to the known position of the Sun. In an energy window between 0.54 MeV to 0.74 MeV, selected using the dominant scintillation light, we have measured 10887$^{+2386}_{-2103} (\mathrm{stat.})\pm 947 (\mathrm{syst.})$ ($68\%$ confidence interval) solar neutrinos out of 19904 total events. This corresponds to a $^{7}$Be neutrino interaction rate of 51.6$^{+13.9}_{-12.5}$ counts/(day$\cdot$ 100 ton), which is in agreement with the Standard Solar Model predictions and the previous spectroscopic results of Borexino. The no-neutrino hypothesis can be excluded with $>$5$\sigma$ confidence level. For the first time, we have demonstrated the possibility of utilizing the directional Cherenkov information for sub-MeV solar neutrinos, in a large-scale, high light yield liquid scintillator detector. This measurement provides an experimental proof of principle for future hybrid event reconstruction using both Cherenkov and scintillation signatures simultaneously., Comment: 6 pages, 4 figures, short letter of arXiv:2109.04770
Published: 2021
Full Text: View/download PDF

32. Search for Low-Energy Signals from Fast Radio Bursts with the Borexino Detector

Author: Appel, S., Bagdasarian, Z., Basilico, D., Bellini, G., Benziger, J., Biondi, R., Caccianiga, B., Calaprice, F., Caminata, A., Chepurnov, A., D'Angelo, D., Derbin, A., Di Giacinto, A., Di Marcello, V., Ding, X. F., Di Ludovico, A., Di Noto, L., Drachnev, I., Franco, D., Galbiati, C., Ghiano, C., Giammarchi, M., Goretti, A., Gottel, A. S., Gromov, M., Guffantic, D., Ianni, Aldo, Ianni, Andrea, Jany, A., Kobychev, V., Korga, G., Kumaran, S., Laubenstein, M., Litvinovich, E., Lombardi, P., Lomskaya, I., Ludhova, L., Lukyanchenko, G., Machulin, I., Martyn, J., Meroni, E., Miramonti, L., Misiaszek, M., Muratova, V., Nugmanov, R., Oberauer, L., Orekhov, V., Ortica, F., Pallavicini, M., Pelicci, L., Penek, O., Pietrofaccia, L., Pilipenko, N., Pocar, A., Raikov, G., Ranalli, M. T., Ranucci, G., Razeto, A., Re, A., Redchuk, M., Rossi, N., Schonert, S., Semenov, D., Settanta, G., Skorokhvatov, M., Singhal, A., Smirnov, O., Sotnikov, A., Tartaglia, R., Testera, G., Unzhakov, E., Vishneva, A., Vogelaar, R. B., von Feilitzsch, F., Wojcik, M., Wurm, M., Zavatarelli, S., Zhutikov, I., Zuber, K., and Zuzel, G.
Subjects: High Energy Physics - Experiment, Astrophysics - Instrumentation and Methods for Astrophysics, High Energy Physics - Phenomenology
Abstract: The search for neutrino events in correlation with several of the most intense fast radio bursts (FRBs) has been performed using the Borexino data. We have searched for signals with visible energies above $250$~keV within a time window of $\pm$1000~s corresponding to the detection time of a particular FRB. We also applied an alternative approach based on searching for specific shapes of neutrino-electron scattering spectra in the full exposure spectrum of the Borexino detector. In particular, two incoming neutrino spectra were considered: the monoenergetic line and the spectrum expected from supernovae. The same spectra were considered for electron antineutrinos detected through the inverse beta-decay reaction. No statistically significant excess over the background was observed. As a result, the strongest upper limits on FRB-associated neutrino fluences of all flavors have been obtained in the $0.5 - 50$~MeV neutrino energy range., Comment: 14 pages, 10 figures
Published: 2021
Full Text: View/download PDF

33. E-Defense 2015 ten-story building: beam–column joint assessment according to different code-based design

Author: Del Vecchio, C., De Risi, M. T., Del Gaudio, C., Ricci, P., Di Ludovico, M., and Kang, Jae-do
Published: 2023
Full Text: View/download PDF

34. Correlated and Integrated Directionality for sub-MeV solar neutrinos in Borexino

Author: Agostini, M., Altenmüller, K., Appel, S., Atroshchenko, V., Bagdasarian, Z., Basilico, D., Bellini, G., Benziger, J., Biondi, R., Bravo, D., Caccianiga, B., Calaprice, F., Caminata, A., Cavalcante, P., Chepurnov, A., D'Angelo, D., Davini, S., Derbin, A., Di Giacinto, A., Di Marcello, V., Ding, X. F., Di Ludovico, A., Di Noto, L., Drachnev, I., Formozov, A., Franco, D., Galbiati, C., Ghiano, C., Giammarchi, M., Goretti, A., Göttel, A. S., Gromov, M., Guffanti, D., Ianni, Aldo, Ianni, Andrea, Jany, A., Jeschke, D., Kobychev, V., Korga, G., Kumaran, S., Laubenstein, M., Litvinovich, E., Lombardi, P., Lomskaya, I., Ludhova, L., Lukyanchenko, G., Lukyanchenko, L., Machulin, I., Martyn, J., Meroni, E., Meyer, M., Miramonti, L., Misiaszek, M., Muratova, V., Neumair, B., Nieslony, M., Nugmanov, R., Oberauer, L., Orekhov, V., Ortica, F., Pallavicini, M., Papp, L., Pellicci, L., Penek, Ö., Pietrofaccia, L., Pilipenko, N., Pocar, A., Raikov, G., Ranalli, M. T., Ranucci, G., Razeto, A., Re, A., Redchuk, M., Romani, A., Rossi, N., Schönert, S., Semenov, D., Settanta, G., Skorokhvatov, M., Singhal, A., Smirnov, O., Sotnikov, A., Suvorov, Y., Tartaglia, R., Testera, G., Thurn, J., Unzhakov, E., Vishneva, A., Vogelaar, R. B., von Feilitzsch, F., Wessel, A., Wojcik, M., Wonsak, B., Wurm, M., Zavatarelli, S., Zuber, K., and Zuzel, G.
Subjects: High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract: Liquid scintillator detectors play a central role in the detection of neutrinos from various sources. In particular, it is the only technique used so far for the precision spectroscopy of sub-MeV solar neutrinos, as demonstrated by the Borexino experiment at the Gran Sasso National Laboratory in Italy. The benefit of a high light yield, and thus a low energy threshold and a good energy resolution, comes at the cost of the directional information featured by water Cherenkov detectors, measuring $^8$B solar neutrinos above a few MeV. In this paper we provide the first directionality measurement of sub-MeV solar neutrinos which exploits the correlation between the first few detected photons in each event and the known position of the Sun for each event. This is also the first signature of directionality in neutrinos elastically scattering off electrons in a liquid scintillator target. This measurement exploits the sub-dominant, fast Cherenkov light emission that precedes the dominant yet slower scintillation light signal. Through this measurement, we have also been able to extract the rate of $^{7}$Be solar neutrinos in Borexino. The demonstration of directional sensitivity in a traditional liquid scintillator target paves the way for the possible exploitation of the Cherenkov light signal in future kton-scale experiments using liquid scintillator targets. Directionality is important for background suppression as well as the disentanglement of signals from various sources., Comment: 19 pages, 15 Figures, revised version after comments from PRD Referees, shorter letter submitted with the title: "First Directional Measurement of sub-MeV Solar Neutrinos with Borexino"
Published: 2021
Full Text: View/download PDF

35. Identification of the cosmogenic $^{11}$C background in large volumes of liquid scintillators with Borexino

Author: Agostini, M., Altenmüller, K., Appel, S., Atroshchenko, V., Bagdasarian, Z., Basilico, D., Bellini, G., Benziger, J., Biondi, R., Bravo, D., Caccianiga, B., Calaprice, F., Caminata, A., Cavalcante, P., Chepurnov, A., D'Angelo, D., Davini, S., Derbin, A., Di Giacintio, A., Di Marcello, V., Ding, X. F., Di Ludovico, A., Di Noto, L., Drachnev, I., Formozov, A., Franco, D., Galbiati, C., Ghiano, C., Giammarchi, M., Goretti, A., Göttel, A. S., Gromov, M., Guffanti, D., Ianni, Aldo, Ianni, Andrea, Jany, A., Jeschke, D., Kobychev, V., Korga, G., Kumaran, S., Laubenstein, M., Litvinovich, E., Lombardi, P., Lomskaya, I., Ludhova, L., Lukyanchenko, G., Lukyanchenko, L., Machulin, I., Martyn, J., Meroni, E., Meyer, M., Miramonti, L., Misiaszek, M., Muratova, V., Neumair, B., Nieslony, M., Nugmanov, R., Oberauer, L., Orekhov, V., Ortica, F., Pallavicini, M., Papp, L., Pelicci, L., Penek, Ö., Pietrofaccia, L., Pilipenko, N., Pocar, A., Porcelli, A., Raikov, G., Ranalli, M. T., Ranucci, G., Razeto, A., Re, A., Redchuk, M., Romani, A., Rossi, N., Schönert, S., Semenov, D., Settanta, G., Skorokhvatov, M., Singha, A., Smirnov, O., Sotnikov, A., Suvorov, Y., Tartaglia, R., Testera, G., Thurn, J., Unzhakov, E., Vishneva, A., Vogelaar, R. B., von Feilitzsch, F., Wojcik, M., Wurm, M., Zavatarelli, S., Zuber, K., and Zuzel, G.
Subjects: Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract: Cosmogenic radio-nuclei are an important source of background for low-energy neutrino experiments. In Borexino, cosmogenic $^{11}$C decays outnumber solar $pep$ and CNO neutrino events by about ten to one. Highly efficient identification of this background is mandatory for these neutrino analyses. We present here the details of the most consolidated strategy, used throughout Borexino solar neutrino measurements. It hinges upon finding the space-time correlations between $^{11}$C decays, the preceding parent muons and the accompanying neutrons. This article describes the working principles and evaluates the performance of this Three-Fold Coincidence (TFC) technique in its two current implementations: a hard-cut and a likelihood-based approach. Both show stable performances throughout Borexino Phases II (2012-2016) and III (2016-2020) data sets, with a $^{11}$C tagging efficiency of $\sim$90 % and $\sim$63-66 % of the exposure surviving the tagging. We present also a novel technique that targets specifically $^{11}$C produced in high-multiplicity during major spallation events. Such $^{11}$C appear as a burst of events, whose space-time correlation can be exploited. Burst identification can be combined with the TFC to obtain about the same tagging efficiency of $\sim$90 % but with a higher fraction of the exposure surviving, in the range of $\sim$66-68 %., Comment: 21 pages, 14 figures (but 15 files, one figure being made of 2 images), 3 tables
Published: 2021
Full Text: View/download PDF

36. The Low Polonium Field of Borexino and its significance for the CNO neutrino detection

Author: Kumaran, S., Agostini, M., Altenmüller, K., Appel, S., Atroshchenko, V., Bagdasarian, Z., Basilico, D., Bellini, G., Benziger, J., Biondi, R., Bravo, D., Caccianiga, B., Calaprice, F., Caminata, A., Cavalcante, P., Chepurnov, A., D'Angelo, D., Davini, S., Derbin, A., Di Giacinto, A., Di Marcello, V., Ding, X. F., Di Ludovico, A., Di Noto, L., Drachnev, I., Formozov, A., Franco, D., Galbiati, C., Ghiano, C., Giammarchi, M., Goretti, A., Göttel, A. S., Gromov, M., Guffanti, D., Ianni, Aldo, Ianni, Andrea, Jany, A., Jeschke, D., Kobychev, V., Korga, G., Laubenstein, M., Litvinovich, E., Lombardi, P., Lomskaya, I., Ludhova, L., Lukyanchenko, G., Lukyanchenko, L., Machulin, I., Martyn, J., Meroni, E., Meyer, M., Miramonti, L., Misiaszek, M., Muratova, V., Neumair, B., Nieslony, M., Nugmanov, R., Oberauer, L., Orekhov, V., Ortica, F., Pallavicini, M., Papp, L., Pellicci, L., Penek, Ö., Pietrofaccia, L., Pilipenko, N., Pocar, A., Raikov, G., Ranalli, M. T., Ranucci, G., Razeto, A., Re, A., Redchuk, M., Romani, A., Rossi, N., Schönert, S., Semenov, D., Settanta, G., Skorokhvatov, M., Singhal, A., Smirnov, O., Sotnikov, A., Suvorov, Y., Tartaglia, R., Testera, G., Thurn, J., Unzhakov, E., Villante, F. L., Vishneva, A., Vogelaar, R. B., von Feilitzsch, F., Wojcik, M., Wurm, M., Zavatarelli, S., Zuber, K., and Zuzel, G.
Subjects: Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract: Borexino is a liquid scintillator detector located at the Laboratori Nazionale del Gran Sasso, Italy with the main goal to measure solar neutrinos. The experiment recently provided the first direct experimental evidence of CNO-cycle neutrinos in the Sun, rejecting the no-CNO signal hypothesis with a significance greater than 5$\sigma$ at 99\%C.L. The intrinsic $^{210}$Bi is an important background for this analysis due to its similar spectral shape to that of CNO neutrinos. $^{210}$Bi can be measured through its daughter $^{210}$Po which can be distinguished through an event-by-event basis via pulse shape discrimination. However, this required reducing the convective motions in the scintillator that brought additional $^{210}$Po from peripheral sources. This was made possible through the thermal insulation and stabilization campaign performed between 2015 and 2016. This article will explain the strategy and the different methods performed to extract the $^{210}$Bi upper limit in Phase-III (Jul 2016- Feb 2020) of the experiment through the analysis of $^{210}$Po in the cleanest region of the detector called the Low Polonium Field., Comment: Contribution to the 2021 Neutrinos session of the 55th Rencontres de Moriond
Published: 2021

37. First detection of CNO neutrinos with Borexino

Author: Settanta, G., Agostini, M., Altenmüller, K., Appel, S., Atroshchenko, V., Bagdasarian, Z., Basilico, D., Bellini, G., Benziger, J., Biondi, R., Bravo, D., Caccianiga, B., Calaprice, F., Caminata, A., Cavalcante, P., Chepurnov, A., D'Angelo, D., Davini, S., Derbin, A., Di Giacinto, A., Di Marcello, V., Ding, X. F., Di Ludovico, A., Di Noto, L., Drachnev, I., Formozov, A., Franco, D., Galbiati, C., Ghiano, C., Giammarchi, M., Goretti, A., Göttel, A. S., Gromov, M., Guffanti, D., Ianni, Aldo, Ianni, Andrea, Jany, A., Jeschke, D., Kobychev, V., Korga, G., Kumaran, S., Laubenstein, M., Litvinovich, E., Lombardi, P., Lomskaya, I., Ludhova, L., Lukyanchenko, G., Lukyanchenko, L., Machulin, I., Martyn, J., Meroni, E., Meyer, M., Miramonti, L., Misiaszek, M., Muratova, V., Neumair, B., Nieslony, M., Nugmanov, R., Oberauer, L., Orekhov, V., Ortica, F., Pallavicini, M., Papp, L., Pelicci, L., Penek, Ö., Pietrofaccia, L., Pilipenko, N., Pocar, A., Raikov, G., Ranalli, M. T., Ranucci, G., Razeto, A., Re, A., Redchuk, M., Romani, A., Rossi, N., Schönert, S., Semenov, D., Skorokhvatov, M., Singhal, A., Smirnov, O., Sotnikov, A., Suvorov, Y., Tartaglia, R., Testera, G., Thurn, J., Unzhakov, E., Villante, F. L., Vishneva, A., Vogelaar, R. B., von Feilitzsch, F., Wojcik, M., Wurm, M., Zavatarelli, S., Zuber, K., and Zuzel, G.
Subjects: High Energy Physics - Experiment
Abstract: Neutrinos are elementary particles which are known since many years as fundamental messengers from the interior of the Sun. The Standard Solar Model, which gives a theoretical description of all nuclear processes which happen in our star, predicts that roughly 99% of the energy produced is coming from a series of processes known as the "pp chain". Such processes have been studied in detail over the last years by means of neutrinos, thanks also to the important measurements provided by the Borexino experiment. The remaining 1% is instead predicted to come from a separate loop-process, known as the "CNO cycle". This sub-dominant process is theoretically well understood, but has so far escaped any direct observation. Another fundamental aspect is that the CNO cycle is indeed the main nuclear engine in stars more massive than the Sun. In 2020, thanks to the unprecedented radio-purity and temperature control achieved by the Borexino detector over recent years, the first ever detection of neutrinos from the CNO cycle has been finally announced. The milestone result confirms the existence of this nuclear fusion process in our Universe. Here, the details of the detector stabilization and the analysis techniques adopted are reported., Comment: 7 pages, 3 figures. Contribution to the 2021 Neutrinos session of the 55th Rencontres de Moriond
Published: 2021

38. High sensitivity characterization of an ultra-high purity NaI(Tl) crystal scintillator with the SABRE proof-of-principle detector

Author: Calaprice, F., Copello, S., Dafinei, I., D'Angelo, D., D'Imperio, G., Di Carlo, G., Diemoz, M., Di Giacinto, A., Di Ludovico, A., Ianni, A., Iannone, M., Marchegiani, F., Mariani, A., Milana, S., Nisi, S., Nuti, F., Orlandi, D., Pettinacci, V., Pietrofaccia, L., Rahatlou, S., Souza, M., Suerfu, B., Tomei, C., Vignoli, C., Wada, M., and Zani, A.
Subjects: Physics - Instrumentation and Detectors, High Energy Physics - Experiment, Nuclear Experiment
Abstract: We present new results on the radiopurity of a 3.4-kg NaI(Tl) crystal scintillator operated in the SABRE proof-of-principle detector setup. The amount of potassium contamination, determined by the direct counting of radioactive $^{40}$K, is found to be $2.2\pm1.5$ ppb, lowest ever achieved for NaI(Tl) crystals. With the active veto, the average background rate in the crystal in the 1-6 keV energy region-of-interest (ROI) is $1.20\pm0.05$ counts/day/kg/keV, which is a breakthrough since the DAMA/LIBRA experiment. Our background model indicates that the rate is dominated by $^{210}$Pb and that about half of this contamination is located in the PTFE reflector. We discuss ongoing developments of the crystal manufacture aimed at the further reduction of the background, including data from purification by zone refining. A projected background rate lower than $\sim$0.2 counts/day/kg/keV in the ROI is within reach. These results represent a benchmark for the development of next-generation NaI(Tl) detector arrays for the direct detection of dark matter particles.
Published: 2021
Full Text: View/download PDF

39. Acute Respiratory Failure in Children: A Clinical Update on Diagnosis

Author: Beatrice Panetti, Ilaria Bucci, Armando Di Ludovico, Giulia Michela Pellegrino, Paola Di Filippo, Sabrina Di Pillo, Francesco Chiarelli, Marina Attanasi, and Giuseppe Francesco Sferrazza Papa
Subjects: acute respiratory failure, children, lung function, lung ultrasound, chest X-ray, chest computed tomography, Pediatrics, RJ1-570
Abstract: Acute respiratory failure (ARF) is a sudden failure of the respiratory system to ensure adequate gas exchanges. Numerous clinical conditions may cause ARF, including pneumonia, obstructive lung diseases (e.g., asthma), restrictive diseases such as neuromuscular diseases (e.g., spinal muscular atrophy and muscular dystrophy), and albeit rarely, interstitial lung diseases. Children, especially infants, may be more vulnerable to ARF than adults due to anatomical and physiological features of the respiratory system. Assessing respiratory impairment in the pediatric population is particularly challenging as children frequently present difficulties in reporting symptoms and due to compliance and cooperation in diagnostic tests. The evaluation of clinical and anamnestic aspects represents the cornerstone of ARF diagnosis: first level exams (e.g., arterial blood gas analysis) confirm and evaluate the severity of the ARF and second level exams help to uncover the underlying cause. Prompt management is critical, with supplemental oxygen, mechanical ventilation, and the treatment of the underlying problem. The aim of this review is to provide a comprehensive summary of the current state of the art in diagnosing pediatric ARF, with a focus on pathophysiology, novel imaging applications, and new perspectives, such as biomarkers and artificial intelligence.
Published: 2024
Full Text: View/download PDF

40. The benefits of physical therapy in juvenile idiopathic arthritis

Author: Di Ludovico, Armando, La Bella, Saverio, Di Donato, Giulia, Felt, Jon, Chiarelli, Francesco, and Breda, Luciana
Published: 2023
Full Text: View/download PDF

41. Allelic heterogeneity and abnormal vesicle recycling in PLAA-related neurodevelopmental disorders

Author: Michele Iacomino, Nadia Houerbi, Sara Fortuna, Jennifer Howe, Shan Li, Giovanna Scorrano, Antonella Riva, Kai-Wen Cheng, Mandy Steiman, Iskra Peltekova, Afiqah Yusuf, Simona Baldassari, Serena Tamburro, Paolo Scudieri, Ilaria Musante, Armando Di Ludovico, Sara Guerrisi, and Ganna Balagura
Subjects: PLAA gene, de novo variants, neurodevelopmental disorders, synaptic transmission, SNAREopathies, developmental regression, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Abstract: The human PLAA gene encodes Phospholipase-A2-Activating-Protein (PLAA) involved in trafficking of membrane proteins. Through its PUL domain (PLAP, Ufd3p, and Lub1p), PLAA interacts with p97/VCP modulating synaptic vesicles recycling. Although few families carrying biallelic PLAA variants were reported with progressive neurodegeneration, consequences of monoallelic PLAA variants have not been elucidated. Using exome or genome sequencing we identified PLAA de-novo missense variants, affecting conserved residues within the PUL domain, in children affected with neurodevelopmental disorders (NDDs), including psychomotor regression, intellectual disability (ID) and autism spectrum disorders (ASDs). Computational and in-vitro studies of the identified variants revealed abnormal chain arrangements at C-terminal and reduced PLAA-p97/VCP interaction, respectively. These findings expand both allelic and phenotypic heterogeneity associated to PLAA-related neurological disorders, highlighting perturbed vesicle recycling as a potential disease mechanism in NDDs due to genetic defects of PLAA.
Published: 2024
Full Text: View/download PDF

42. Characterization of SABRE crystal NaI-33 with direct underground counting

Author: Antonello, M., Arnquist, I. J., Barberio, E., Baroncelli, T., Benziger, J., Bignell, L. J., Bolognino, I., Calaprice, F., Copello, S., Dafinei, I., D'Angelo, D., D'Imperio, G., D'Incecco, M., Di Carlo, G., Diemoz, M., Di Giacinto, A., Di Ludovico, A., Dix, W., Duffy, A. R., Hoppe, E., Ianni, A., Iannone, M., Ioannucci, L., Krishnan, S., Lane, G. J., Mahmood, I., Mariani, A., Milana, S., Mould, J., Nuti, F., Orlandi, D., Pettinacci, V., Pietrofaccia, L., Rahatlou, S., Scutti, F., Souza, M., Stuchbery, A. E., Suerfu, B., Tomei, C., Urquijo, P., Vignoli, C., Wallner, A., Wada, M., Williams, A. G., Zani, A., and Zurowski, M.
Subjects: Physics - Instrumentation and Detectors
Abstract: Ultra-pure NaI(Tl) crystals are the key element for a model-independent verification of the long standing DAMA result and a powerful means to search for the annual modulation signature of dark matter interactions. The SABRE collaboration has been developing cutting-edge techniques for the reduction of intrinsic backgrounds over several years. In this paper we report the first characterization of a 3.4 kg crystal, named NaI-33, performed in an underground passive shielding setup at LNGS. NaI-33 has a record low $^{39}$K contamination of 4.3$\pm$0.2 ppb as determined by mass spectrometry. We measured a light yield of 11.1$\pm$0.2 photoelectrons/keV and an energy resolution of 13.2% (FWHM/E) at 59.5 keV. We evaluated the activities of $^{226}$Ra and $^{228}$Th inside the crystal to be $5.9\pm0.6 \mu$Bq/kg and $1.6\pm0.3 \mu$Bq/kg, respectively, which would indicate a contamination from $^{238}$U and $^{232}$Th at part-per-trillion level. We measured an activity of 0.51$\pm$0.02 mBq/kg due to $^{210}$Pb out of equilibrium and a $\alpha$ quenching factor of 0.63$\pm$0.01 at 5304 keV. We illustrate the analyses techniques developed to reject electronic noise in the lower part of the energy spectrum. A cut-based strategy and a multivariate approach indicated a rate, attributed to the intrinsic radioactivity of the crystal, of $\sim$1 count/day/kg/keV in the [5-20] keV region.
Published: 2020
Full Text: View/download PDF

43. Experimental evidence of neutrinos produced in the CNO fusion cycle in the Sun

Author: Agostini, M., Altenmüller, K., Appel, S., Atroshchenko, V., Bagdasarian, Z., Basilico, D., Bellini, G., Benziger, J., Biondi, R., Bravo, D., Caccianiga, B., Calaprice, F., Caminata, A., Cavalcante, P., Chepurnov, A., D'Angelo, D., Davini, S., Derbin, A., Di Giacinto, A., Di Marcello, V., Ding, X. F., Di Ludovico, A., Di Noto, L., Drachnev, I., Formozov, A., Franco, D., Galbiati, C., Ghiano, C., Giammarchi, M., Goretti, A., Göttel, A. S., Gromov, M., Guffanti, D., Ianni, Aldo, Ianni, Andrea, Jany, A., Jeschke, D., Kobychev, V., Korga, G., Kumaran, S., Laubenstein, M., Litvinovich, E., Lombardi, P., Lomskaya, I., Ludhova, L., Lukyanchenko, G., Lukyanchenko, L., Machulin, I., Martyn, J., Meroni, E., Meyer, M., Miramonti, L., Misiaszek, M., Muratova, V., Neumair, B., Nieslony, M., Nugmanov, R., Oberauer, L., Orekhov, V., Ortica, F., Pallavicini, M., Papp, L., Pellicci, L., Penek, Ö., Pietrofaccia, L., Pilipenko, N., Pocar, A., Raikov, G., Ranalli, M. T., Ranucci, G., Razeto, A., Re, A., Redchuk, M., Romani, A., Rossi, N., Schönert, S., Semenov, D., Settanta, G., Skorokhvatov, M., Singhal, A., Smirnov, O., Sotnikov, A., Suvorov, Y., Tartaglia, R., Testera, G., Thurn, J., Unzhakov, E., Villante, F. L., Vishneva, A., Vogelaar, R. B., von Feilitzsch, F., Wojcik, M., Wurm, M., Zavatarelli, S., Zuber, K., and Collaboration, G. Zuzel. The BOREXINO
Subjects: High Energy Physics - Experiment, Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Solar and Stellar Astrophysics, Physics - Instrumentation and Detectors, G.3.1
Abstract: For most of their existence stars are fueled by the fusion of hydrogen into helium proceeding via two theoretically well understood processes, namely the $pp$ chain and the CNO cycle. Neutrinos emitted along such fusion processes in the solar core are the only direct probe of the deep interior of the star. A complete spectroscopy of neutrinos from the {\it pp} chain, producing about 99\% of the solar energy, has already been performed \cite{bib:Nature-2018}. Here, we report the direct observation, with a high statistical significance, of neutrinos produced in the CNO cycle in the Sun. This is the first experimental evidence of this process obtained with the unprecedentedly radio-pure large-volume liquid-scintillator Borexino detector located at the underground Laboratori Nazionali del Gran Sasso in Italy. The main difficulty of this experimental effort is to identify the excess of the few counts per day per 100 tonnes of target due to CNO neutrino interactions above the backgrounds. A novel method to constrain the rate of \bi contaminating the scintillator relies on the thermal stabilisation of the detector achieved over the past 5 years. In the CNO cycle, the hydrogen fusion is catalyzed by the carbon (C) - nitrogen (N) - oxygen (O) and thus its rate, as well as the flux of emitted CNO neutrinos, directly depends on the abundance of these elements in solar core. Therefore, this result paves the way to a direct measurement of the solar metallicity by CNO neutrinos. While this result quantifies the relative contribution of the CNO fusion in the Sun to be of the order of 1\%, this process is dominant in the energy production of massive stars. The occurrence of the primary mechanism for the stellar conversion of hydrogen into helium in the Universe has been proven., Comment: 43 pages, 14 figures
Published: 2020
Full Text: View/download PDF

44. Sensitivity to neutrinos from the solar CNO cycle in Borexino

Author: Agostini, M., Altenmüller, K., Appel, S., Atroshchenko, V., Bagdasarian, Z., Basilico, D., Bellini, G., Benziger, J., Biondi, R., Bravo, D., Caccianiga, B., Calaprice, F., Caminata, A., Cavalcante, P., Chepurnov, A., D'Angelo, D., Davini, S., Derbin, A., Di Giacinto, A., Di Marcello, V., Ding, X. F., Di Ludovico, A., Di Noto, L., Drachnev, I., Formozov, A., Franco, D., Galbiati, C., Ghiano, C., Giammarchi, M., Goretti, A., Göttel, A. S., Gromov, M., Guffanti, D., Ianni, Aldo, Ianni, Andrea, Jany, A., Jeschke, D., Kobychev, V., Korga, G., Kumaran, S., Laubenstein, M., Litvinovich, E., Lombardi, P., Lomskaya, I., Ludhova, L., Lukyanchenko, G., Lukyanchenko, L., Machulin, I., Martyn, J., Meroni, E., Meyer, M., Miramonti, L., Misiaszek, M., Muratova, V., Neumair, B., Nieslony, M., Nugmanov, R., Oberauer, L., Orekhov, V., Ortica, F., Pallavicini, M., Papp, L., Penek, Ö., Pietrofaccia, L., Pilipenko, N., Pocar, A., Raikov, G., Ranalli, M. T., Ranucci, G., Razeto, A., Re, A., Redchuk, M., Romani, A., Rossi, N., Schönert, S., Semenov, D., Settanta, G., Skorokhvatov, M., Smirnov, O., Sotnikov, A., Suvorov, Y., Tartaglia, R., Testera, G., Thurn, J., Unzhakov, E., Villante, F. L., Vishneva, A., Vogelaar, R. B., von Feilitzsch, F., Wojcik, M., Wurm, M., Zavatarelli, S., Zuber, K., and Zuzel, G.
Subjects: High Energy Physics - Experiment, Astrophysics - Solar and Stellar Astrophysics, Physics - Instrumentation and Detectors
Abstract: Neutrinos emitted in the carbon, nitrogen, oxygen (CNO) fusion cycle in the Sun are a sub-dominant, yet crucial component of solar neutrinos whose flux has not been measured yet. The Borexino experiment at the Laboratori Nazionali del Gran Sasso (Italy) has a unique opportunity to detect them directly thanks to the detector's radiopurity and the precise understanding of the detector backgrounds. We discuss the sensitivity of Borexino to CNO neutrinos, which is based on the strategies we adopted to constrain the rates of the two most relevant background sources, pep neutrinos from the solar pp-chain and Bi-210 beta decays originating in the intrinsic contamination of the liquid scintillator with Pb-210. Assuming the CNO flux predicted by the high-metallicity Standard Solar Model and an exposure of 1000 daysx71.3 t, Borexino has a median sensitivity to CNO neutrino higher than 3 sigma. With the same hypothesis the expected experimental uncertainty on the CNO neutrino flux is 23%, provided the uncertainty on the independent estimate of the Bi-210 interaction rate is 1.5 cpd/100t. Finally, we evaluated the expected uncertainty of the C and N abundances and the expected discrimination significance between the high and low metallicity Standard Solar Models (HZ and LZ) with future more precise measurement of the CNO solar neutrino flux., Comment: 16 pages, 12 figures
Published: 2020
Full Text: View/download PDF

45. A simulation tool for crisis management and pre-disaster planning.

Author: Federico Eugeni, Sara Sacco, Donato Di Ludovico, and Antinisca Di Marco
Published: 2023
Full Text: View/download PDF

46. Optimization of Structural Health Monitoring for Bridges Networks by Combining Traditional and Innovative Techniques

Author: Miano, Andrea, Lobianco, Alessandro Lubrano, Mele, Annalisa, Fiorillo, Antimo, Di Ludovico, Marco, Prota, Andrea, di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Limongelli, Maria Pina, editor, Giordano, Pier Francesco, editor, Quqa, Said, editor, Gentile, Carmelo, editor, and Cigada, Alfredo, editor
Published: 2023
Full Text: View/download PDF

47. A Prosumer Approach for Feeding the Digital Twin. Testing the MUST Application in the Old Harbour Waterfront of Genoa

Author: Viola, Serena, Novellino, Antonio, Zinno, Alberto, Di Ludovico, Marco, Angelidou, Margarita, Editorial Board Member, Farnaz Arefian, Fatemeh, Editorial Board Member, Batty, Michael, Editorial Board Member, Davoudi, Simin, Editorial Board Member, DeVerteuil, Geoffrey, Editorial Board Member, González Pérez, Jesús M., Editorial Board Member, Hess, Daniel B., Editorial Board Member, Jones, Paul, Editorial Board Member, Karvonen, Andrew, Editorial Board Member, Kirby, Andrew, Editorial Board Member, Kropf, Karl, Editorial Board Member, Lucas, Karen, Editorial Board Member, Maretto, Marco, Editorial Board Member, Modarres, Ali, Editorial Board Member, Neuhaus, Fabian, Editorial Board Member, Nijhuis, Steffen, Editorial Board Member, Aráujo de Oliveira, Vitor Manuel, Editorial Board Member, Silver, Christopher, Editorial Board Member, Strappa, Giuseppe, Editorial Board Member, Vojnovic, Igor, Editorial Board Member, Yamu, Claudia, Editorial Board Member, Zhao, Qunshan, Editorial Board Member, Arbizzani, Eugenio, editor, Cangelli, Eliana, editor, Clemente, Carola, editor, Cumo, Fabrizio, editor, Giofrè, Francesca, editor, Giovenale, Anna Maria, editor, Palme, Massimo, editor, and Paris, Spartaco, editor
Published: 2023
Full Text: View/download PDF

48. FRP Seismic Strengthening of Infilled RC Frames

Author: Del Vecchio, Ciro, Di Ludovico, Marco, Balsamo, Alberto, Prota, Andrea, di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Ilki, Alper, editor, Çavunt, Derya, editor, and Çavunt, Yavuz Selim, editor
Published: 2023
Full Text: View/download PDF

49. Seismic Damage Assessment for RC Buildings from SHM Data

Author: Lubrano Lobianco, Alessandro, Del Zoppo, Marta, Di Ludovico, Marco, di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Ilki, Alper, editor, Çavunt, Derya, editor, and Çavunt, Yavuz Selim, editor
Published: 2023
Full Text: View/download PDF

50. Towards Earthquake Risk Reduction Solutions: Applications of Composite Materials and Future Challenges

Author: Di Ludovico, Marco, di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Ilki, Alper, editor, Çavunt, Derya, editor, and Çavunt, Yavuz Selim, editor
Published: 2023
Full Text: View/download PDF

Catalog

Books, media, physical & digital resources

See catalog results

Searchworks

Select search scope, currently: Articles Catalog books, media & more in Jio Institute collections Articles journal articles & other e-resources

Search

Search Constraints

Refine your results

Search Limiters

Topic

Publication Year Range

Language

Publication Type

Journal

Region

Database

Publisher

1,429 results on '"A Di Ludovico"'

Search Results

Catalog

Select search scope, currently: Articles

Catalog

books, media & more in Jio Institute collections

Articles

journal articles & other e-resources