1,304 results on '"A, Labani"'
Search Results
2. Continuous Intention to Use Online Learning during COVID-19 Pandemic Based on Three Different Theoretical Models (TAM, SVT, TOE)
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Masadeh, Shaden, Abumalloh, Rabab, and Labani, Noha
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The novel COVID-19 pandemic has impacted educational systems in almost all countries worldwide. Traditional classes have been canceled or shifted to online mode through the affected countries. Resuming traditional face-to-face instruction might be delayed. This unexpectedly fast and mandatory shifting to online education, along with the significant challenges that face learners and instructors, has led to uncertainty regarding its future. This study aims to inspect students' continuous intention (CI) towards online education during COVID-19, by incorporating different constructs from three theoretical models: first, conservation values (Security (SEC), Conformity (CON)) of Schwartz Value Theory (SVT), organizational support factors (Training (TR), Top management support (TS)) in Technology-Organizational-Environmental (TOE), and the Technology acceptance model (TAM) main factors (perceived usefulness (PU), perceived ease of use (PEU)). To achieve the research goal, a research model was developed referring to previous strong literature. The data was gathered from 310 students from Imam Abdulrahman Bin Faisal university (IAU) in Saudi Arabia, and analyzed with Structural Equation Modelling SEM-PLS. Findings show that TAM factors (PU, PEU), conservation values factors (SEC, CON), and organizational support factors (TR, TS) are important determinants for online learning adoption during COVID-19 pandemic. The study provides directions for designers and developers to establish a more effective online learning environment, which is more suited for the new digitized generation during unexpected conditions.
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- 2023
3. Tracking Supermassive Black Hole Mergers from kpc to sub-pc Scales with AXIS
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Foord, Adi, Cappelluti, Nico, Liu, Tingting, Volonteri, Marta, Habouzit, Melanie, Pacucci, Fabio, Marchesi, Stefano, Chen, Nianyi, Di Matteo, Tiziana, Mallick, Labani, and Koss, Michael
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Astrophysics of Galaxies - Abstract
We present an analysis showcasing how the Advanced X-ray Imaging Satellite (AXIS), a proposed NASA Probe-class mission, will significantly increase our understanding of supermassive black holes undergoing mergers -- from kpc to sub-pc scales. In particular, the AXIS point spread function, field of view, and effective area are expected to result in (1) the detection of hundreds to thousands of new dual AGNs across the redshift range 0 < z < 5 and (2) blind searches for binary AGNs that are exhibiting merger signatures in their light curves and spectra. AXIS will detect some of the highest-redshift dual AGNs to date, over a large range of physical separations. The large sample of AGN pairs detected by AXIS (over a magnitude more than currently known) will result in the first X-ray study that quantifies the frequency of dual AGNs as a function of redshift up to z = 4., Comment: 22 pages, 5 figures. Accepted to Universe (05/24/2024)
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- 2023
4. Prospects for Time-Domain and Multi-Messenger Science with AXIS
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Time-Domain, The AXIS, Group, Multi-Messenger Science Working, Arcodia, Riccardo, Bauer, Franz E., Cenko, S. Bradley, Dage, Kristen C., Haggard, Daryl, Ho, Wynn C. G., Kara, Erin, Koss, Michael, Liu, Tingting, Mallick, Labani, Negro, Michela, Pradhan, Pragati, Quirola-Vasquez, J., Reynolds, Mark T., Ricci, Claudio, Rothschild, Richard E., Sridhar, Navin, Troja, Eleonora, and Yao, Yuhan
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The Advanced X-ray Imaging Satellite (AXIS) promises revolutionary science in the X-ray and multi-messenger time domain. AXIS will leverage excellent spatial resolution (<1.5 arcsec), sensitivity (80x that of Swift), and a large collecting area (5-10x that of Chandra) across a 24-arcmin diameter field of view to discover and characterize a wide range of X-ray transients from supernova-shock breakouts to tidal disruption events to highly variable supermassive black holes. The observatory's ability to localize and monitor faint X-ray sources opens up new opportunities to hunt for counterparts to distant binary neutron star mergers, fast radio bursts, and exotic phenomena like fast X-ray transients. AXIS will offer a response time of <2 hours to community alerts, enabling studies of gravitational wave sources, high-energy neutrino emitters, X-ray binaries, magnetars, and other targets of opportunity. This white paper highlights some of the discovery science that will be driven by AXIS in this burgeoning field of time domain and multi-messenger astrophysics., Comment: This White Paper is part of a series commissioned for the AXIS Probe Concept Mission; additional AXIS White Papers can be found at http://axis.astro.umd.edu
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- 2023
5. The High Energy X-ray Probe (HEX-P): The Future of Hard X-ray Dual AGN Science
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Pfeifle, Ryan W., Boorman, Peter G., Weaver, Kimberly A., Buchner, Johannes, Civano, Francesca, Madsen, Kristin, Stern, Daniel, Torres-Albà, Núria, Nardini, Emanuele, Ricci, Claudio, Marchesi, Stefano, Ballantyne, D. R., Sicilian, Dominic, Chen, Chien-Ting, Kammoun, Elias, Hickox, Ryan C., García, Javier A., and Mallick, Labani
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Astrophysics of Galaxies ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
A fundamental goal of modern-day astrophysics is to understand the connection between supermassive black hole (SMBH) growth and galaxy evolution. Merging galaxies offer one of the most dramatic channels for galaxy evolution known, capable of driving inflows of gas into galactic nuclei, potentially fueling both star formation and central SMBH activity. Dual active galactic nuclei (dual AGNs) in late-stage mergers with nuclear pair separations $<10$ kpc are thus ideal candidates to study SMBH growth along the merger sequence since they coincide with the most transformative period for galaxies. However, dual AGNs can be extremely difficult to confirm and study. Hard X-ray ($>10$ keV) studies offer a relatively contamination-free tool for probing the dense obscuring environments predicted to surround the majority of dual AGN in late-stage mergers. To date, only a handful of the brightest and closest systems have been studied at these energies due to the demanding instrumental requirements involved. We demonstrate the unique capabilities of HEX-P to spatially resolve the soft and - for the first time - hard X-ray counterparts of closely-separated ($\sim2''-5''$) dual AGNs in the local Universe. By incorporating state-of-the-art physical torus models, we reproduce realistic broadband X-ray spectra expected for deeply embedded accreting SMBHs. Hard X-ray spatially resolved observations of dual AGNs - accessible only to HEX-P - will hence transform our understanding of dual AGN in the nearby Universe., Comment: Under review for Frontiers in Astronomy and Space Sciences
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- 2023
6. Variability as a predictor for the hard-to-soft state transition in GX 339-4
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Lucchini, Matteo, Have, Marina Ten, Wang, Jingyi, Homan, Jeroen, Kara, Erin, Adegoke, Oluwashina, Connors, Riley, Dauser, Thomas, Garcia, Javier, Mastroserio, Guglielmo, Ingram, Adam, van der Klis, Michiel, König, Ole, Lewin, Collin, Mallick, Labani, Nathan, Edward, O'Neill, Patrick, Panagiotou, Christos, Piotrowska, Joanna, and Uttley, Phil
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
During the outbursts of black hole X-ray binaries (BHXRBs), their accretion flows transition through several states. The source luminosity rises in the hard state, dominated by non-thermal emission, before transitioning to the blackbody-dominated soft state. As the luminosity decreases, the source transitions back into the hard state and fades to quiescence. This picture does not always hold, as $\approx$ 40$\%$ of the outbursts never leave the hard state. Identifying the physics that govern state transitions remains one of the outstanding open questions in black hole astrophysics. In this paper we present an analysis of archival RXTE data of multiple outbursts of GX 339-4. We compare the properties of the X-ray variability and time-averaged energy spectrum and demonstrate that the variability (quantified by the power spectral hue) systematically evolves $\approx$ 10-40 days ahead of the canonical state transition (quantified by a change in spectral hardness); no such evolution is found in hard state only outbursts. This indicates that the X-ray variability can be used to predict if and when the hard-to-soft state transition will occur. Finally, we find a similar behavior in ten outbursts of four additional BHXRBs with more sparse observational coverage. Based on these findings, we suggest that state transitions in BHXRBs might be driven by a change in the turbulence in the outer regions of the disk, leading to a dramatic change in variability. This change is only seen in the spectrum days to weeks later, as the fluctuations propagate inwards towards the corona., Comment: Accepted for publication in ApJ
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- 2023
7. Assessing the impact of financial resources on Sorghum yield in Al-Qadarif State, Sudan
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Eissa, Abdelazim, Tong, Guangji, Sagali, Heri Labani, Yusif, Suliman, and Fadol, Ahmed A. A.
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- 2024
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8. Bacteriophage therapy for the treatment of Mycobacterium tuberculosis infections in humanized mice
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Yang, Fan, Labani-Motlagh, Alireza, Bohorquez, Jose Alejandro, Moreira, Josimar Dornelas, Ansari, Danish, Patel, Sahil, Spagnolo, Fabrizio, Florence, Jon, Vankayalapati, Abhinav, Sakai, Tsuyoshi, Sato, Osamu, Ikebe, Mitsuo, Vankayalapati, Ramakrishna, Dennehy, John J., Samten, Buka, and Yi, Guohua
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- 2024
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9. Cancer Cells Show Higher Sensitivity to Melatonin-Tamoxifen Drug Conjugates than to Combination of Melatonin and Tamoxifen
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Mohamed Akmal Marzouk, Sara Greco, Florence Gbahou, Jenni Küblbeck, Nedjma Labani, Ralf Jockers, Ulrike Holzgrabe, Lisa Wiesmüller, and Darius P. Zlotos
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Chemistry ,QD1-999 - Published
- 2024
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10. Assessing the impact of financial resources on Sorghum yield in Al-Qadarif State, Sudan
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Abdelazim Eissa, Guangji Tong, Heri Labani Sagali, Suliman Yusif, and Ahmed A. A. Fadol
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Agricultural production ,Financial resources ,Food security ,Sorghum production ,Sudan ,Agriculture (General) ,S1-972 ,Environmental sciences ,GE1-350 - Abstract
Abstract The sorghum agricultural sector in Al-Qadarif State, Sudan, plays a pivotal role in ensuring regional food security. However, its productivity is hindered by significant constraints. Substantial improvements in sorghum yield are impeded by the intricate complexities that characterize this sector's financial resources, and agricultural practices. This study in Al-Qadarif State, Sudan, explores the relationship between financial resources and sorghum agrarian productivity. Data were collected from 200 sorghum farmers using standardized questionnaires during the 2022 season, and regression analysis was employed to investigate the association between financial factors and sorghum productivity. The findings indicate that financial accessibility considerations significantly influence sorghum productivity. This emphasizes the importance of improved financial resources for farmers to adopt innovative farming technologies and practices, leading to higher sorghum productivity levels. The study recommends the integration of digital financial services and precision agriculture technologies as a creative solution to enhance financial accessibility and sorghum productivity. By leveraging mobile money platforms and digital credit services, farmers can conveniently access financial resources, enabling them to invest in modern agricultural inputs and technologies. Additionally, the adoption of precision agriculture techniques, such as soil moisture sensors, drone-based crop monitoring, and variable rate application of inputs, can optimize resource utilization, increase yield, and reduce production costs. The combination of these innovative approaches has the potential to bridge the financial and knowledge gaps, promoting the widespread adoption of sustainable agricultural practices. This synergistic approach could significantly improve sorghum productivity, enhance farmer livelihoods, and contribute to regional food security.
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- 2024
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11. Variability in soil organic carbon pools in different land use systems in the north-eastern region of India
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SUNITA YADAV, MANDIRA BARMAN, K M MANJAIAH, T J PURAKAYASTHA, LABANI ROY, R K YADAV, MD YEASIN, and SEEMA
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Active and passive carbon, Carbon management index, Carbon pools, Lability index, Land use systems ,Agriculture - Abstract
The current study was carried out during 2020 to 2022, at Horticulture Research Centre (HRC), Nagicherra, Agartala, Tripura to assess and compare the effects of various land use systems, including bamboo, tea, mango, lemon, rice-rice, wheat-millet, okra-onion and uncultivated soils, on soil organic carbon (SOC) dynamics. SOC is a critical component of terrestrial ecosystems, influencing soil health, fertility and carbon sequestration potential. The NEH region of India, Tripura characterized by its diverse agro-ecological zones and land use systems (LUS), presents a unique opportunity to investigate the various land use regimes' effects on SOC pools. Walkley and Black carbon (WBC) significantly vary among the selected LUS, ranging from 7.14–12.48 g/kg, with the maximum values in tea LUS. In 0–30 cm depth, very labile C (CVL) pools are very variable among the selected LUS (2.04–5.35 g/kg), which is the highest in tea and mango compared to the uncultivated system. The C pools in selected LUS indicated the deviation depth and land use pattern. Lability index (LI) varies from 1.50–1.63 and 1.40–1.74 in 0–30 cm and 30–60 cm depth, respectively. Carbon pool index (CPI) assessed highest in tea LUS, 1.78 and 2.1 from 0–30 and 30–60 cm, respectively. Carbon management index (CMI) was higher in selected LUS compared to uncultivated system.
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- 2024
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12. Youth Involvement in Beekeeping and Forest Conservation: A Case Study of Manyoni District, Tanzania
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Sagali, Heri Labani, Mendako, Richard, Mauri, Jerry, Mohamed, Suliman, Harbi, Jun, Ogra, Aurobindo, Yingli, Huang, Pisello, Anna Laura, Editorial Board Member, Hawkes, Dean, Editorial Board Member, Bougdah, Hocine, Editorial Board Member, Rosso, Federica, Editorial Board Member, Abdalla, Hassan, Editorial Board Member, Boemi, Sofia-Natalia, Editorial Board Member, Mohareb, Nabil, Editorial Board Member, Mesbah Elkaffas, Saleh, Editorial Board Member, Bozonnet, Emmanuel, Editorial Board Member, Pignatta, Gloria, Editorial Board Member, Mahgoub, Yasser, Editorial Board Member, De Bonis, Luciano, Editorial Board Member, Kostopoulou, Stella, Editorial Board Member, Pradhan, Biswajeet, Editorial Board Member, Abdul Mannan, Md., Editorial Board Member, Alalouch, Chaham, Editorial Board Member, Gawad, Iman O., Editorial Board Member, Nayyar, Anand, Editorial Board Member, Amer, Mourad, Series Editor, Ksibi, Mohamed, editor, Negm, Abdelazim, editor, Hentati, Olfa, editor, Ghorbal, Achraf, editor, Sousa, Arturo, editor, Rodrigo-Comino, Jesus, editor, Panda, Sandeep, editor, Lopes Velho, José, editor, El-Kenawy, Ahmed M., editor, and Perilli, Nicola, editor
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- 2024
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13. The long-stable hard state of XTE J1752-223 and the disk truncation dilemma
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Connors, Riley M. T., Garcia, Javier A., Tomsick, John, Mastroserio, Guglielmo, Grinberg, Victoria, Steiner, James F., Jiang, Jiachen, Fabian, Andrew C., Parker, Michael L., Harrison, Fiona, Hare, Jeremy, Mallick, Labani, and Lazar, Hadar
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
The degree to which the thin accretion disks of black hole X-ray binaries are truncated during hard spectral states remains a contentious open question in black hole astrophysics. During its singular observed outburst in $2009\mbox{--}2010$, the black hole X-ray binary XTE J1752-223 spent $\sim1$~month in a long-stable hard spectral state at a luminosity of $\sim0.02\mbox{--}0.1~L_{\rm Edd}$. It was observed with 56 RXTE pointings during this period, with simultaneous Swift-XRT daily coverage during the first 10 days of the RXTE observations. Whilst reflection modeling has been extensively explored in the analysis of these data, there is a disagreement surrounding the geometry of the accretion disk and corona implied by the reflection features. We re-examine the combined, high signal-to-noise, simultaneous Swift and RXTE observations, and perform extensive reflection modeling with the latest relxill suite of reflection models, including newer high disk density models. We show that reflection modeling requires that the disk be within $\sim5~R_{\rm ISCO}$ during the hard spectral state, whilst weaker constraints from the thermal disk emission imply higher truncation ($R_{\rm in}=6\mbox{--}80~R_{\rm ISCO}$). We also explore more complex coronal continuum models, allowing for two Comptonization components instead of one, and show that the reflection features still require only a mildly truncated disk. Finally we present a full comparison of our results to previous constraints found from analyses of the same dataset., Comment: 18 pages, 9 figures, accepted by ApJ
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- 2022
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14. EXPLORING THE CULTURE OF MATUA COMUNITY IN THAKURNAGAR
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Kirtania, Labani, primary
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- 2024
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15. ANNEGA: an artificial neural network embedded genetic algorithm approach for energy efficient street lighting.
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Pragna Labani Sikdar, Samarjit Kar, and Parag Kumar Guha Thakurta
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- 2024
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16. MRI quantitative T1 and T2 mapping of the renal cortex: Assessment of normal values and potential usefulness for renal masses at 3 T
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Henry, Remy, Goetsch, Thibaut, Brandhuber, Laurent, Labani, Aissam, Moliére, Sébastien, Ohana, Mickael, and Roy, Catherine
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- 2024
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17. Bacteriophage therapy for the treatment of Mycobacterium tuberculosis infections in humanized mice
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Fan Yang, Alireza Labani-Motlagh, Jose Alejandro Bohorquez, Josimar Dornelas Moreira, Danish Ansari, Sahil Patel, Fabrizio Spagnolo, Jon Florence, Abhinav Vankayalapati, Tsuyoshi Sakai, Osamu Sato, Mitsuo Ikebe, Ramakrishna Vankayalapati, John J. Dennehy, Buka Samten, and Guohua Yi
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Biology (General) ,QH301-705.5 - Abstract
Abstract The continuing emergence of new strains of antibiotic-resistant bacteria has renewed interest in phage therapy; however, there has been limited progress in applying phage therapy to multi-drug resistant Mycobacterium tuberculosis (Mtb) infections. In this study, we show that bacteriophage strains D29 and DS6A can efficiently lyse Mtb H37Rv in 7H10 agar plates. However, only phage DS6A efficiently kills H37Rv in liquid culture and in Mtb-infected human primary macrophages. We further show in subsequent experiments that, after the humanized mice were infected with aerosolized H37Rv, then treated with DS6A intravenously, the DS6A treated mice showed increased body weight and improved pulmonary function relative to control mice. Furthermore, DS6A reduces Mtb load in mouse organs with greater efficacy in the spleen. These results demonstrate the feasibility of developing phage therapy as an effective therapeutic against Mtb infection.
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- 2024
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18. Report on Workshop on “Geothermal Energy Resources of India: Present Status and Way Forward” at CSIR-National Geophysical Research Institute, Hyderabad
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Ray, Labani, Chopra, Nishu, Podugu, Nagaraju, Sarolkar, P. B., Dutta, Ayan, Prajapati, Sandeep Kumar, and Dudhate, Amar Prakashrao
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- 2023
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19. Segmentation-Free Estimation of Left Ventricular Ejection Fraction Using 3D CNN Is Reliable and Improves as Multiple Cardiac MRI Cine Orientations Are Combined
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Philippe Germain, Aissam Labani, Armine Vardazaryan, Nicolas Padoy, Catherine Roy, and Soraya El Ghannudi
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left ventricular ejection fraction ,cardiac MRI ,deep learning ,convolutional neural network ,inter-method discrepancy ,multiple orientations combination ,Biology (General) ,QH301-705.5 - Abstract
Objectives: We aimed to study classical, publicly available convolutional neural networks (3D-CNNs) using a combination of several cine-MR orientation planes for the estimation of left ventricular ejection fraction (LVEF) without contour tracing. Methods: Cine-MR examinations carried out on 1082 patients from our institution were analysed by comparing the LVEF provided by the CVI42 software (V5.9.3) with the estimation resulting from different 3D-CNN models and various combinations of long- and short-axis orientation planes. Results: The 3D-Resnet18 architecture appeared to be the most favourable, and the results gradually and significantly improved as several long-axis and short-axis planes were combined. Simply pasting multiple orientation views into composite frames increased performance. Optimal results were obtained by pasting two long-axis views and six short-axis views. The best configuration provided an R2 = 0.83, a mean absolute error (MAE) = 4.97, and a root mean square error (RMSE) = 6.29; the area under the ROC curve (AUC) for the classification of LVEF < 40% was 0.99, and for the classification of LVEF > 60%, the AUC was 0.97. Internal validation performed on 149 additional patients after model training provided very similar results (MAE 4.98). External validation carried out on 62 patients from another institution showed an MAE of 6.59. Our results in this area are among the most promising obtained to date using CNNs with cardiac magnetic resonance. Conclusion: (1) The use of traditional 3D-CNNs and a combination of multiple orientation planes is capable of estimating LVEF from cine-MRI data without segmenting ventricular contours, with a reliability similar to that of traditional methods. (2) Performance significantly improves as the number of orientation planes increases, providing a more complete view of the left ventricle.
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- 2024
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20. Dynamic interactions of green innovations, green transitions and ecological load capacity factor in BRICS
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Uche, Emmanuel, Ngepah, Nicholas, Das, Narasingha, and Dey, Labani
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- 2024
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21. Stress and academic engagement among Saudi undergraduate nursing students: The mediating role of emotion regulation and emotional intelligence
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Sarah Alkharj, Yasir S. Alsalamah, Rabia Allari, Maryam Saad Alharbi, Thamer Alslamah, Lisa Babkair, Safiah Labani, and Mirna Fawaz
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academic engagement ,emotional intelligence ,nursing students ,self‐esteem ,Nursing ,RT1-120 - Abstract
Abstract Aim To assess the mediating role of emotion regulation and emotional intelligence in the relationship between stress and academic engagement among Saudi undergraduate nursing students. Design This study employed a quantitative cross‐sectional research design. Methods The study recruited 367 Saudi undergraduate nursing students at a major Saudi university. Structural equation modelling was used to explore the mediational model. Results The results of the ANOVA and Welch F‐test demonstrated that the emotional intelligence, emotional regulation and academic engagement scores were statistically significantly different according to stress levels (p‐values
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- 2024
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22. The high energy X-ray probe (HEX-P): the future of hard X-ray dual AGN science
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Ryan W. Pfeifle, Peter G. Boorman, Kimberly A. Weaver, Johannes Buchner, Francesca Civano, Kristin Madsen, Daniel Stern, Núria Torres-Albà, Emanuele Nardini, Claudio Ricci, Stefano Marchesi, D. R. Ballantyne, Dominic Sicilian, Chien-Ting Chen, Elias Kammoun, Ryan C. Hickox, Javier A. García, and Labani Mallick
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dual AGN ,galaxy merger ,x-ray astronomy ,active galactic nucleus ,galaxy interaction ,Astronomy ,QB1-991 ,Geophysics. Cosmic physics ,QC801-809 - Abstract
A fundamental goal of modern-day astrophysics is to understand the connection between supermassive black hole (SMBH) growth and galaxy evolution. Merging galaxies offer one of the most dramatic channels for galaxy evolution known, capable of driving inflows of gas into galactic nuclei, potentially fueling both star formation and central SMBH activity. Dual active galactic nuclei (dual AGNs) in late-stage mergers with nuclear pair separations 10 keV) studies offer a relatively contamination-free tool for probing the dense obscuring environments predicted to surround the majority of dual AGN in late-stage mergers. To date, only a handful of the brightest and closest systems have been studied at these energies due to the demanding instrumental requirements involved. We demonstrate the unique capabilities of HEX-P to spatially resolve the soft and - for the first time - hard X-ray counterparts of closely-separated (∼2″−5″) dual AGNs in the local Universe. By incorporating physically-motivated obscuration models, we reproduce realistic broadband X-ray spectra expected for deeply embedded accreting SMBHs. Hard X-ray spatially resolved observations of dual AGNs—accessible only to HEX-P—will hence transform our understanding of dual AGN in the nearby Universe.
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- 2024
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23. Case Report: A rare treatable metabolic syndrome (Brown-Vialetto-Van Laere syndrome) masquerading as chronic inflammatory demyelinating polyneuropathy from Saudi Arabia
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Amal Y. Kentab, Yara Alsalloum, Mai Labani, Abrar Hudairi, Muddathir H. Hamad, Dima Z. Jamjoom, Ali H. Alwadei, Reem M. Alhammad, and Fahad A. Bashiri
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pontobulbar palsy ,riboflavin transporter deficiency ,Brown-Vialetto-Van Laere syndrome ,MRI ,chronic inflammatory demyelinating polyneuropathy ,Pediatrics ,RJ1-570 - Abstract
BackgroundBrown-Vialetto-Van Laere (BVVL) syndrome is an extremely rare autosomal recessive progressive motoneuron disease that is caused by a defect in the riboflavin transporter genes SLC52A2 and SLC52A3. BVVL syndrome has a variable age of presentation, and it is characterized by progressive auditory neuropathy, bulbar palsy, stridor, muscle weakness, and respiratory compromise secondary to diaphragmatic and vocal cord paralysis. BVVL syndrome has a poor prognosis in the absence of treatment, including morbidity with quadriparesis and sensorineural hearing loss, with mortality in the younger age group. Early administration of riboflavin is associated with prolonged survival, low morbidity, and reversal of some clinical manifestations.Case presentationWe describe an 18-month-old male infant with progressive pontobulbar palsy, loss of developmental milestones, and a clinical picture suggestive of chronic inflammatory demyelinating neuropathy. A nerve conduction study revealed axonal neuropathy, while molecular analysis revealed a homozygous mutation in one of the riboflavin transporter genes, SLC52A3, confirming BVVL syndrome. The patient needed long-term respiratory support and a gastrostomy tube to support feeding. With high-dose riboflavin supplementation, he experienced moderate recovery of motor function.ConclusionThis report highlights the importance of considering BVVL syndrome in any patient who presents with the clinical phenotype of pontobulbar palsy and peripheral axonal neuropathy, as early riboflavin treatment may improve or halt disease progression, thus reducing the associated mortality and morbidity.
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- 2024
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24. Left atrial remodeling and voltage-guided ablation outcome in obese patients with persistent atrial fibrillation
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Halim Marzak, Simon Fitouchi, Aïssam Labani, Justine Hammann, Romain Ringele, Mohamad Kanso, Thomas Cardi, Alexandre Schatz, Patrick Ohlmann, Olivier Morel, and Laurence Jesel
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atrial fibrillation ,catheter ablation ,obesity ,low-voltage zones ,bipolar voltage map ,atrial remodeling ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
BackgroundObesity is a risk factor for atrial fibrillation (AF). Data regarding left atrial (LA) remodeling in obese patients are scarce. Whether obesity favors AF recurrence after catheter ablation (CA) is still controversial. We assessed the distribution of epicardial atrial fat on computed tomography (CT), LA bipolar voltage, low-voltage zone (LVZ) extent, and the outcome of voltage-guided ablation of persistent AF in obese and non-obese patients.MethodsA total of 139 patients with persistent AF undergoing a first voltage-guided ablation were enrolled and divided into two groups: 74 were non-obese and 65 were obese. Epicardial adipose tissue (EAT) was assessed on a CT scanner. LA endocardial voltage maps were obtained using a 3D mapping system in sinus rhythm. LVZ was defined as a bipolar peak-to-peak voltage amplitude
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- 2024
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25. Half-metallicity from CrCoSi and MnCoSi half-Heusler alloys to their derivative double half-Heusler CrMn[Co.sub.2][Si.sub.2]
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Elarabi, Hiba, Khelfaoui, Friha, Boudia, Keltouma, Labani, Fatima, Hamlat, Mama, Sadouki, Ouafaa, Belkharroubi, Fadila, Faid, Fares, Bouhemadou, Abdelmadjid, and Deghfel, Bahri
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Silicon alloys -- Mechanical properties -- Magnetic properties -- Electric properties ,Density functionals -- Usage ,Cobalt alloys -- Mechanical properties -- Magnetic properties -- Electric properties ,Spintronics -- Research ,Physics - Abstract
The structural, elastic, electronic, and magnetic properties of the CrCoSi, MnCoSi parent half-Heusler (HH) alloys, and their CrMn[Co.sub.2][Si.sub.2] derivative double half-Heusler (DHH) compound are studied, utilizing the augmented plane wave method, which is based on density functional theory and implemented in the WIEN2k code. The stability of HH structure of the CrCoSi and MnCoSi alloys has been checked for their non-magnetic and ferromagnetic phases, leading to that the latter phase of the type I arrangement is the most stable. The CrMn[Co.sub.2][Si.sub.2] DHH alloy, derivative from the found structural and magnetic ground states of CrCoSi and MnCoSi HH alloys, is constructed and investigated. This DDH as well as its CrCoSi parent HH are found to be resistant to deformation and can be classified as ductile materials, whereas the MnCoSi compound is brittle. By the gradient generalized approximation (GGA), the electronic structures of CrCoSi, MnCoSi, and CrMn[Co.sub.2][Si.sub.2]compounds exhibit a metallic behavior in the spin-up channel and a semiconducting behavior in the spin-dn channel, with band gaps (half-metallic gaps) of 0. 851(0.020), 0.852(0.021), and 0.531(0.002) eV, respectively. The half-metallicity of CrMn[Co.sub.2][Si.sub.2] DHH is retained with smaller (larger) band gap (half-metallic gap) of 0.38(0.106) eV than that of GGA, using GGA + U approximation. In addition, the total magnetic moments are found to be 1, 2, and 3 [[mu].sub.B] for CrCoSi, MnCoSi, and CrMn[Co.sub.2][Si.sub.2], respectively. Therefore, these alloys can be good candidates for spinitronic applications due to their half-metallicity. Key words: half-metal, heusler alloys, spin polarization, mechanical stability, FP-LAPW, 1. Introduction Spin-based electronics has grown into a significant field of study that spans a wide range of high spin-polarized materials, used in spintronic devices. It overcomes the limitations of [...]
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- 2023
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26. Comparative studying the effect of Establishing Good Faith in the Degree of Doctor\'s Responsibility with Emphasis on French Jurisprudence and Law
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mostafa nourollahi, seyed kamal sajadi, and Mohammad Sadegh Labani Motlagh
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good faith ,medical jurisprudence ,civil responsibility ,doctor's responsibility ,medical ethics ,Law - Abstract
The sanctity of the medical profession in our society is rooted in both religious teachings and rich Iranian culture. For this reason, in Islamic jurisprudence, the subject of medicine and Iatrology has been the subject of extensive technical and legal discussions as a separate chapter. On the other hand, the principle of good faith and mutual trust in the doctor-patient relationship requires both parties by respecting their agreement, do not refuse to fulfill their obligations without a valid excuse. The main question is to what extent the good faith is based on the responsibility of the doctor. It is affect? In this article, with a comparative study of the French legal system and jurisprudential sources, while examining the theories related to the relationship between the doctor's responsibility and the intention of beneficence and good faith, it was concluded that the existence of good faith is both effective and also is regarded as a factor to reduce the amount of damage which is compensable.
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- 2023
27. Correlation Between Maxillary Anterior Teeth and Common Facial Measurements
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Alshamri HA, Al Moaleem MM, Al-Huthaifi BH, Al-labani MA, Naseeb WR, Daghriri SM, Suhail IM, Hamzi WH, Abu Illah MJ, Thubab AY, Aljabali SA, and AlNehmi MM
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dental measurement ,facial measurement ,anterior teeth ,yemen ,Dentistry ,RK1-715 - Abstract
Hameed A Alshamri,1 Mohammed M Al Moaleem,2 Basem H Al-Huthaifi,3 Mohammed A Al-labani,4 Weaam RB Naseeb,5 Shahad Mohammed Daghriri,5 Ibtihaj Mohammed Suhail,5 Wasan H Hamzi,5 Mohammed J Abu Illah,5 Abdulaziz Yahya Thubab,5 Shuaib A Aljabali,3 Mohammed M AlNehmi1 1Department of Restorative and Prosthodontics, College of Dentistry, University of Science and Technology, Sana’a City, Yemen; 2Department of Prosthetic Dental Science, College of Dentistry, Jazan University, Jazan, Saudi Arabia; 3Department of Preventive and Biomedical Science, College of Dentistry, University of Science and Technology, Sana’a City, Yemen; 4Department of Orthodontics, College of Dentistry, University of Sana’a, Sana’a City, Yemen; 5College of Dentistry, Jazan University, Jazan, Saudi ArabiaCorrespondence: Mohammed M Al Moaleem, Department of Prosthetic Dental Science, College of Dentistry, Jazan University, Jazan, 45142, Saudi Arabia, Email malmoaleem@jazanu.edu.saBackground: The symmetry between maxillary anterior teeth and the face holds significant importance. This study assessed and analyzed the relationship between facial parameters and anterior teeth in the maxillary arch of male and female subjects. Specifically, individual width and combined width (CW) measurements of the maxillary anterior teeth were investigated.Methods: This study involved a total of 150 dentate Yemeni subjects (74 men and 76 women), whose ages ranged from 18 years old to 30 years old. A maxillary cast was created, and two digital photographs of the face of each subject were taken and analyzed. Digital calipers and AutoCAD were used to gather measurement data of the dental parameters (intercanthal distance [ICD], interpupillary distance [IPD], interalar width [IAW], intercommissural width [ICW], and bizygomatic width [BZW]) and facial parameters (profile distance).Results: Significant correlations were found for the following: IPD and width of six maxillary anterior teeth of each of the study subjects; ICD and their central incisors; and BZW and their canine width measurements. In contrast, IAW and ICW were not correlated with all tooth measurements. Linear regression findings showed that the CW measurement of the four incisors was significantly correlated with all facial parameter measurements, excluding the ICW and IAW in females and the IAW, ICW, and profile distance in males.Conclusion: The IPD and ICD of males and females may be used to determine their CW measurements. The BZW and IPD of males can be used to take precise anthropological measurements of the width of the central canines and incisors. Meanwhile, the IPD distance of females can be used to assess the central and lateral incisor widths.Keywords: dental measurement, facial measurement, anterior teeth, Yemen
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- 2023
28. Burn injury characteristics and outcomes among pediatric and adult patients admitted to Ministry of National Guard Health Affairs (MNGHA) hospitals in Saudi Arabia
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Abrar M. Al-Mutairi, Safiah Labani, Manar J. Alasmari, Muhammed S. Alamri, Abdullah S. Alqahtani, Ibrahim Albabtain, and David G. Greenhalgh
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Burn ,Flame ,Etiology of burn ,Mortality ,Hot liquid ,Dermatology ,RL1-803 ,Medical emergencies. Critical care. Intensive care. First aid ,RC86-88.9 - Abstract
Objective: This study aims to describe the characteristics and outcomes of burn injuries in pediatric and adult patients admitted to Ministry of National Guard Health Affairs (MNGHA) hospitals in Saudi Arabia. Methods: A multicenter retrospective cohort study was conducted between 2015 and 2021 in five hospitals run by the MNGHA in Saudi Arabia. The study included 555 patients who were admitted to the hospital with burns, and data were collected from an institutional trauma registry on various aspects such as sociodemographic variables, burn clinical characteristics and burn outcomes. The differences in epidemiological data, general characteristics, and outcomes of burn patients with ≤18 and >18 years of age among Saudi hospitalized patients. The associations between patient characteristics and burn outcomes were assessed using multivariable logistic regression. Results: Most of the participants representing 66.1% males and females 33.9%. Flame and contact were the most common causes of burn injuries, accounting for 43.6% and 43.2% of cases, respectively; followed by chemical (6.7%), then electrical (5.4%), and friction (1.1%). The study revealed that pediatric were the most frequently admitted age group for burn injuries with most cases occurring at home (57%). Pediatric patients had a higher percentage of hot fluid injuries, accounting for 77.5 % of cases (P = 0.00). Flame injuries were more prevalent in adults, accounting for 65.3% of cases (P
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- 2023
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29. Survival and response to pulmonary vasodilator therapies in patients with chronic obstructive pulmonary disease and pulmonary vascular phenotype
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Steger, Mathilde, Canuet, Matthieu, Enache, Irina, Goetsch, Thibaut, Labani, Aissam, Meyer, Léo, Martin, Guillaume, Kessler, Romain, Montani, David, and Riou, Marianne
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- 2024
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30. Discovery of soft and hard X-ray time lags in low-mass AGNs
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Mallick, Labani, Wilkins, Daniel R., Alston, William N., Markowitz, Alex, De Marco, Barbara, Parker, Michael L., Lohfink, Anne M., and Stalin, C. S.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Cosmology and Nongalactic Astrophysics ,Astrophysics - Astrophysics of Galaxies - Abstract
The scaling relations between the black hole (BH) mass and soft lag properties for both active galactic nuclei (AGNs) and BH X-ray binaries (BHXRBs) suggest the same underlying physical mechanism at work in accreting BH systems spanning a broad range of mass. However, the low-mass end of AGNs has never been explored in detail. In this work, we extend the existing scaling relations to lower-mass AGNs, which serve as anchors between the normal-mass AGNs and BHXRBs. For this purpose, we construct a sample of low-mass AGNs ($M_{\rm BH}<3\times 10^{6} M_{\rm \odot}$) from the XMM-Newton archive and measure frequency-resolved time delays between the soft (0.3-1 keV) and hard (1-4 keV) X-ray emissions. We report that the soft band lags behind the hard band emission at high frequencies $\sim[1.3-2.6]\times 10^{-3}$ Hz, which is interpreted as a sign of reverberation from the inner accretion disc in response to the direct coronal emission. At low frequencies ($\sim[3-8]\times 10^{-4}$ Hz), the hard band lags behind the soft band variations, which we explain in the context of the inward propagation of luminosity fluctuations through the corona. Assuming a lamppost geometry for the corona, we find that the X-ray source of the sample extends at an average height and radius of $\sim 10r_{\rm g}$ and $\sim 6r_{\rm g}$, respectively. Our results confirm that the scaling relations between the BH mass and soft lag amplitude/frequency derived for higher-mass AGNs can safely extrapolate to lower-mass AGNs, and the accretion process is indeed independent of the BH mass., Comment: 11 pages, 5 figures, 4 tables, Published in MNRAS
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- 2021
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31. Prospects for Time-Domain and Multi-Messenger Science with AXIS
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Riccardo Arcodia, Franz E. Bauer, S. Bradley Cenko, Kristen C. Dage, Daryl Haggard, Wynn C. G. Ho, Erin Kara, Michael Koss, Tingting Liu, Labani Mallick, Michela Negro, Pragati Pradhan, J. Quirola-Vásquez, Mark T. Reynolds, Claudio Ricci, Richard E. Rothschild, Navin Sridhar, Eleonora Troja, and Yuhan Yao
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time-domain astronomy ,multi-messenger astronomy ,gravitational waves ,high-energy neutrinos ,Elementary particle physics ,QC793-793.5 - Abstract
The Advanced X-ray Imaging Satellite (AXIS) promises revolutionary science in the X-ray and multi-messenger time domain. AXIS will leverage excellent spatial resolution (80× that of Swift), and a large collecting area (5–10× that of Chandra) across a 24-arcmin diameter field of view at soft X-ray energies (0.3–10.0 keV) to discover and characterize a wide range of X-ray transients from supernova-shock breakouts to tidal disruption events to highly variable supermassive black holes. The observatory’s ability to localize and monitor faint X-ray sources opens up new opportunities to hunt for counterparts to distant binary neutron star mergers, fast radio bursts, and exotic phenomena like fast X-ray transients. AXIS will offer a response time of
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- 2024
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32. Energy Efficient Street Lighting: A GIS Approach
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Kabir, Kazi Amrin, Sikdar, Pragna Labani, Guha Thakurta, Parag Kumar, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Pati, Bibudhendu, editor, Panigrahi, Chhabi Rani, editor, Mohapatra, Prasant, editor, and Li, Kuan-Ching, editor
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- 2023
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33. Approximate DBSCAN on obfuscated data
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Sadhukhan, Payel, Halder, Labani, and Palit, Sarbani
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- 2024
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34. Enhancing Manganese Availability for Plants through Microbial Potential: A Sustainable Approach for Improving Soil Health and Food Security
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Bahman Khoshru, Debasis Mitra, Alireza Fallah Nosratabad, Adel Reyhanitabar, Labani Mandal, Beatrice Farda, Rihab Djebaili, Marika Pellegrini, Beatriz Elena Guerra-Sierra, Ansuman Senapati, Periyasamy Panneerselvam, and Pradeep Kumar Das Mohapatra
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manganese (Mn) ,microbial interactions ,soil health ,sustainable agriculture ,plant growth promotion ,Specialties of internal medicine ,RC581-951 - Abstract
Manganese (Mn) is essential for plant growth, as it serves as a cofactor for enzymes involved in photosynthesis, antioxidant synthesis, and defense against pathogens. It also plays a role in nutrient uptake, root growth, and soil microbial communities. However, the availability of Mn in the soil can be limited due to factors like soil pH, redox potential, organic matter content, and mineralogy. The excessive use of chemical fertilizers containing Mn can lead to negative consequences for soil and environmental health, such as soil and water pollution. Recent research highlights the significance of microbial interactions in enhancing Mn uptake in plants, offering a more environmentally friendly approach to address Mn deficiencies. Microbes employ various strategies, including pH reduction, organic acid production, and the promotion of root growth, to increase Mn bioavailability. They also produce siderophores, anti-pathogenic compounds, and form symbiotic relationships with plants, thereby facilitating Mn uptake, transport, and stimulating plant growth, while minimizing negative environmental impacts. This review explores the factors impacting the mobility of Mn in soil and plants, and highlights the problems caused by the scarcity of Mn in the soil and the use of chemical fertilizers, including the consequences. Furthermore, it investigates the potential of different soil microbes in addressing these challenges using environmentally friendly methods. This review suggests that microbial interactions could be a promising strategy for improving Mn uptake in plants, resulting in enhanced agricultural productivity and environmental sustainability. However, further research is needed to fully understand these interactions’ mechanisms and optimize their use in agricultural practices.
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- 2023
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35. Impact of inspiration level on lung nodule volumetry
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Arnaud Halter, Aïssam Labani, Catherine Roy, and Mickaël Ohana
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Nodule ,Size ,Volumetry ,Inspiratory level ,Residual volume ,Medicine (General) ,R5-920 - Published
- 2024
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36. The high energy X-ray probe (HEX-P): probing the physics of the X-ray corona in active galactic nuclei
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Elias Kammoun, Anne M. Lohfink, Megan Masterson, Dan R. Wilkins, Xiurui Zhao, Mislav Balokovic, Peter G. Boorman, Riley Connors, Paolo Coppi, Andrew Fabian, Javier A. García, Kristin K. Madsen, Nicole Rodriguez Cavero, Navin Sridhar, Daniel Stern, John Tomsick, Thomas Wevers, Dominic J. Walton, Stefano Bianchi, Johannes Buchner, Francesca M. Civano, Giorgio Lanzuisi, Labani Mallick, Giorgio Matt, Andrea Merloni, Emanuele Nardini, Joanna M. Piotrowska, Claudio Ricci, Ka-Wah Wong, and Abderahmen Zoghbi
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accretion ,x-ray astronomy ,black holes ,active galactic nuclei ,quasars ,tidal disruption events ,Astronomy ,QB1-991 ,Geophysics. Cosmic physics ,QC801-809 - Abstract
The hard X-ray emission in active galactic nuclei (AGN) and black hole X-ray binaries is thought to be produced by a hot cloud of electrons referred to as the corona. This emission, commonly described by a power law with a high-energy cutoff, is suggestive of Comptonization by thermal electrons. While several hypotheses have been proposed to explain the origin, geometry, and composition of the corona, we still lack a clear understanding of this fundamental component. NuSTAR has been playing a key role improving our knowledge of X-ray coronæ thanks to its unprecedented sensitivity above 10 keV. However, these constraints are limited to bright, nearby sources. The High Energy X-ray Probe (HEX-P) is a probe-class mission concept combining high spatial resolution X-ray imaging and broad spectral coverage (0.2–80 keV) with a sensitivity superior to current facilities. In this paper, we highlight the major role that HEX-P will play in further advancing our insights of X-ray coronæ notably in AGN. We demonstrate how HEX-P will measure key properties and track the temporal evolution of coronæ in unobscured AGN. This will allow us to determine their electron distribution and test the dominant emission mechanisms. Furthermore, we show how HEX-P will accurately estimate the coronal properties of obscured AGN in the local Universe, helping address fundamental questions about AGN unification. In addition, HEX-P will characterize coronæ in a large sample of luminous quasars at cosmological redshifts for the first time and track the evolution of coronæ in transient systems in real time. We also demonstrate how HEX-P will enable estimating the coronal geometry using spectral-timing techniques. HEX-P will thus be essential to understand the evolution and growth of black holes over a broad range of mass, distance, and luminosity, and will help uncover the black holes’ role in shaping the Universe.
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- 2024
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37. Potential added value of an AI software with prediction of malignancy for the management of incidental lung nodules
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Michelin, Bastien, Labani, Aïssam, Bilbault, Pascal, Roy, Catherine, and Ohana, Mickaël
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- 2023
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38. Burn injury characteristics and outcomes among pediatric and adult patients admitted to Ministry of National Guard Health Affairs (MNGHA) hospitals in Saudi Arabia
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Al-Mutairi, Abrar M., Labani, Safiah, Alasmari, Manar J., Alamri, Muhammed S., Alqahtani, Abdullah S., Albabtain, Ibrahim, and Greenhalgh, David G.
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- 2023
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39. Efficacious tuning in energy efficient street lighting.
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Pragna Labani Sikdar, Abhinav Anurag, and Parag Kumar Guha Thakurta
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- 2023
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40. Comments on 'Superior Skin Penetration of Diclofenac from Dynapar QPS Plus as Compared to Diclofenac Aerosol Spray' by Mansuri et al.
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Deepak Kumar, Labani Biswas, and Shamith Kumar P
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pharmacokinetics ,quick penetrating solution ,topical drug ,Medicine - Published
- 2024
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41. Tracking Supermassive Black Hole Mergers from kpc to sub-pc Scales with AXIS
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Adi Foord, Nico Cappelluti, Tingting Liu, Marta Volonteri, Melanie Habouzit, Fabio Pacucci, Stefano Marchesi, Nianyi Chen, Tiziana Di Matteo, Labani Mallick, and Michael Koss
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AGN ,X-ray astrophysics ,mergers ,SMBH ,accretion ,Elementary particle physics ,QC793-793.5 - Abstract
We present an analysis showcasing how the Advanced X-ray Imaging Satellite (AXIS), a proposed NASA Probe-class mission, will significantly increase our understanding of supermassive black holes undergoing mergers—from kpc to sub-pc scales. In particular, the AXIS point spread function, field of view, and effective area are expected to result in (1) the detection of hundreds to thousands of new dual AGNs across the redshift range 0
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- 2024
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42. Potential added value of an AI software with prediction of malignancy for the management of incidental lung nodules
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Bastien Michelin, Aïssam Labani, Pascal Bilbault, Catherine Roy, and Mickaël Ohana
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Lung nodule ,Lung cancer ,Artificial intelligence ,Radiomics ,Deep learning ,Medicine (General) ,R5-920 - Abstract
Purpose: To determine the impact of an artificial intelligence software predicting malignancy in the management of incidentally discovered lung nodules. Materials and methods: In this retrospective study, all lung nodules ≥ 6 mm and ≤ 30 mm incidentally discovered on emergency CT scans performed between June 1, 2017 and December 31, 2017 were assessed. Artificial intelligence software using deep learning algorithms was applied to determine their likelihood of malignancy: most likely benign (AI score < 50%), undetermined (AI score 50–75%) or probably malignant (AI score > 75%). Predictions were compared to two-year follow-up and Brock's model. Results: Ninety incidental pulmonary nodules in 83 patients were retrospectively included. 36 nodules were benign, 13 were malignant and 41 remained indeterminate at 2 years follow-up.AI analysis was possible for 81/90 nodules. The 34 benign nodules had an AI score between 0.02% and 96.73% (mean = 48.05 ± 37.32), while the 11 malignant nodules had an AI score between 82.89% and 100% (mean = 93.9 ± 2.3). The diagnostic performance of the AI software for positive diagnosis of malignant nodules using a 75% malignancy threshold was: sensitivity = 100% [95% CI 72%-100%]; specificity = 55.8% [38–73]; PPV = 42.3% [23–63]; NPV = 100% [82–100]. With its apparent high NPV, the addition of an AI score to the initial CT could have avoided a guidelines-recommended follow-up in 50% of the benign pulmonary nodules (6/12 nodules). Conclusion: Artificial intelligence software using deep learning algorithms presents a strong NPV (100%, with a 95% CI 82–100), suggesting potential use for reducing the need for follow-up of nodules categorized as benign.
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- 2023
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43. Incidence of multiple sclerosis relapses and pseudo-relapses following COVID-19 vaccination
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Labani, Amir, Chou, Scott, Kaviani, Kasra, Ropero, Brenda, Russman, Katharine, and Becker, Daniel
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- 2023
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44. Post-COVID-19 mucormycosis: A prospective, observational study in patients undergoing surgical treatment
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Sonia Wadhawan, Sukhyanti Kerai, Farah Husain, Preeti Labani, Munisha Agarwal, and Kirti N Saxena
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anesthesia ,covid-19 ,debridement ,mucormycosis ,perioperative ,surgical ,Anesthesiology ,RD78.3-87.3 ,Pharmacy and materia medica ,RS1-441 - Abstract
Background and Aims: Post the second wave of COVID-19 in India, our institute became a dedicated center for managing COVID-19-associated mucormycosis (CAM), but there was a paucity of data regarding perioperative considerations in these patients. The objectives of present study was to describe the preoperative clinical profile, the perioperative complications and outcome of CAM patients undergoing urgent surgical debridement. Material and Methods: This prospective observational study was conducted on CAM patients presenting for surgical debridement from July to September 2021. During preoperative visits, evaluation of extent of disease, any side effects of ongoing medical management and post-COVID-19 systemic sequalae were done. The details of anaesthetic management of these patients including airway management, intraoperative haemodynamic complications and need for perioperative blood transfusion were noted. Results: One hundred twenty patients underwent surgical debridement; functional endoscopic sinus surgery (FESS) was carried out in 63% of patients, FESS with orbital exenteration in 17.5%, and maxillectomy in 12.5%. Diabetes mellitus was found in 70.8% and post-COVID new onset hyperglycemia in 29.1% of patients. Moderate-to-severe decline in post-COVID functional status (PCFS) scale was observed in 73.2% of patients, but with optimization, only 5.8% required ICU management. The concern during airway management was primarily difficulty in mask ventilation (17.5%). Intraoperatively, hemodynamic adverse events responded to conventional treatment for hypotension, judicious use of fluids and blood transfusion. Perioperatively, 10.8% of patients required blood transfusion and 4.2% of patients did not survive. Non-surviving patients were older, with a more aggressive involvement of CAM, and had comorbidities and a greater decline in functional capacity. Conclusion: A majority of patients reported a moderate-to-severe decline in PCFS that required a preoperative multisystem optimization and a tailored anesthetic approach for a successful perioperative outcome.
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- 2023
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45. Urinary tract infection in children: A narrative review of clinical practice guidelines
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Basim S Alsaywid, Fahad A Alyami, Naif Alqarni, Khalid Fouda Neel, Talah O Almaddah, Nada M Abdulhaq, Lujin Bassam Alajmani, Mawada O Hindi, Mohammed A Alshayie, Hazim Alsufyani, Sarah Abdulrahman Alajlan, Bashaer I Albulushi, and Safiah K Labani
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children ,clinical practice guidelines ,cystitis ,pediatric ,pyelonephritis ,urinary tract infection ,vesicoureteric reflux ,Diseases of the genitourinary system. Urology ,RC870-923 - Abstract
Background: Urinary tract infection (UTI) has been a major burden on the community and the health-care systems all over the globe. It is the most common cause of bacterial infection in the pediatric age group, with an annual incidence of 3%. The aim of this study is to review and summarize all available guidelines on the diagnosis and management of children with UTI. Materials and Methods: This is a narrative review of the management of children with a UTI. All biomedical databases were searched, and any guidelines published from 2000 to 2022 were retrieved, reviewed, and evaluated to be included in the summary statements. The sections of the articles were formulated according to the availability of information in the included guidelines. Results: UTI diagnoses are based on positive urine culture from a specimen of urine obtained through catheterization or suprapubic aspiration, and diagnoses cannot be established on the bases of urine collected from a bag. The criteria for diagnosing UTI are based on the presence of at least 50,000 colony-forming units per milliliter of a uropathogen. Upon confirmation of UTI, the clinician should instruct parents to seek rapid medical assessment (ideally within 48 h) of future febrile disease to ensure that frequent infections can be detected and treated immediately. The choice of therapy depends on several factors, including the age of the child, underlying medical problems, the severity of the disease, the ability to tolerate oral medications, and most importantly local patterns of uropathogens resistance. Initial antibiotic choice of treatment should be according to the sensitivity results or known pathogens patterns with comparable efficacy of oral and parenteral route, for 7 days to 14 days duration. Renal and bladder ultrasonography is the investigation of choice for febrile UTI, and voiding cystourethrography should not be performed routinely unless indicated. Conclusion: This review summarizes all the recommendations related to UTIs in the pediatric population. Due to the lack of appropriate data, further high-quality studies are required to improve the level and strength of recommendations in the future.
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- 2023
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46. Understanding the role of efficiency in the electricity generation process for promoting human development in India: Findings from the novel multiple threshold nonlinear ARDL modelling
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Das, Narasingha, Gangopadhyay, Partha, Alghamdi, Thamer, Sarwar, Suleman, Haseeb, Mohammad, Barut, Abdulkadir, and Dey, Labani
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- 2023
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47. Multiobjective energy efficient street lighting framework: A data analysis approach
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Sikdar, Pragna Labani, Kar, Samarjit, and Thakurta, Parag Kumar Guha
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- 2022
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48. Approximate DBSCAN on obfuscated data.
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Payel Sadhukhan, Labani Halder, and Sarbani Palit
- Published
- 2024
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49. Development of indolealkylamine derivatives as potential multi-target agents for COVID-19 treatment
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Chauhan, Jyoti, Cecon, Erika, Labani, Nedjma, Gbahou, Florence, Real, Fernando, Bomsel, Morgane, Dubey, Kshatresh Dutta, Das, Ranajit, Dam, Julie, Jockers, Ralf, and Sen, Subhabrata
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- 2023
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50. Corneal neurotization in the management of neurotrophic keratopathy: A review of the literature
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Saad, S., Labani, S., Goemaere, I., Cuyaubere, R., Borderie, M., Borderie, V., Benkhatar, H., and Bouheraoua, N.
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- 2023
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