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Thesis (Ph. D. in Medical Sciences)--University of Tsukuba, (A), no. 4068, 2006.3.24, Joint authors: Teruaki Nomura ... et al, Offprint. Originally published in: Molecular biology of the cell, v. 16, pp. 4705-4713, 2005, Includes bibliographical references, Includes supplementary treatise

Thesis (Ph. D. in Science)--University of Tsukuba, (A), no. 2251, 2000.3.24

Thesis (Ph.D. in Medical Sciences)--University of Tsukuba, (A), no. 1126, 1993.3.25, It has recently been of great importance to understand the regulatory mechanism of proteinase activites, since the action of proteinases has been revaled to be correlated with expression of varios cellular functions such as the signal transduction. ..., http://www.tulips.tsukuba.ac.jp/mylimedio/dl/page.do?bookid=100630805&old_bookid=703471

Phylogenetic relationships among 8 species of white-toothed shrews (Crocidurinae, Mammalia) in East and Central Asia were evaluated based on mitochondrial cytochrome-b gene sequences. The taxon formerly regarded as Crocidura suaveolens in East Asia phylogenetically is distinct from that of true C. suaveolens in Europe, suggesting that specimens in East Asia should be considered a distinct species, C. shantungensis. All shrews from Central Asia were regarded as C. sibirica, although phylogenetic comparison with the unsampled C. gmelini is needed to confirm its taxonomic status. C. shantungensis, C. suaveolens, and C. sibirica formed a well-supported monophyletic group. C. dsinezumi, C. lasiura, C. kurodai, and C. watasei also formed a well-supported monophyletic group. Within C. dsinezumi, there were 2 clusters, referable to western and eastern Japan. Based on low genetic divergence, C. dsinezumi on Cheju and Hokkaido islands appear to be the result of a recent introduction from western Japan and northern-eastern Honshu, respectively.

In yeast expressing the RNA replication proteins encoded by brome mosaic virus (BMV), B3URA3, a BMV RNA3 derivative that harbours the 3a cell-to-cell movement protein gene and the yeast uracil biosynthesis gene URA3, was replicated and maintained in 85–95% of progeny at each cell division. Transmission of the B3URA3 RNA replicon from mother to daughter yeast did not require the 3a gene. Nevertheless, even after passaging for 165 cycles of RNA replication and yeast cell division, each of 40 independent Ura+ colonies tested retained B3URA3 RNAs whose electrophoretic mobilities and accumulation levels were indistinguishable from those of the original B3URA3. These and other results suggest that unselected genes in many positive-strand RNA virus replicons can be stably retained if the presence of the gene does not confer a selective disadvantage in RNA replication.