Search

Gigahertz peaked spectrum (GPS) and compact steep spectrum (CSS) sources are compact radio galaxies (RGs), with jets extending up to 20 kpc and ages <103 yr. They are considered to evolve to Fanaroff–Riley RGs, but the real scenario to explain the compact sources remains unsolved. The young compact jets make GPS/CSS ideal for studying feedback in the nuclear region of active galactic nuclei because the jets are just starting to leave this region. Numerical simulations and jet power estimates suggest that compact sources can drive outflows on scales several times larger than the radio source itself, but the lack of suitable data limits comparisons between theory and observation. We carried out an optical spectroscopic study of 82 CSS/GPS with Sloan Digital Sky Survey-DR12 data to investigate the influence of compact jets in the gas. We found outflowing gas components in the [O iii ] λ 5007 emission lines in half of our sample. The kinetic energy of the outflowing gas in compact sources is comparable to that observed in extended RGs, indicating that the compact jets can drive powerful outflows similar to those in FR RGs. The observed anticorrelation between the kinetic power of the outflow and the radio luminosity suggests an interaction between the young jet and the interstellar medium (ISM). This finding provides significant observational support for previous simulations of jet–ISM interactions and supports the evolutionary scenario for RGs. However, the lack of sources with high kinetic efficiency indicates that some compact galaxies may be frustrated sources. [ABSTRACT FROM AUTHOR]

The flat spectrum radio quasar PKS 1510-089 is one of the most active blazars in γ -rays, exhibiting phases of very high activity. This study investigates its variability over a decade across a wide range of wavelengths, from radio to γ -rays. Utilizing the nonthermal dominance parameter, we analyze the H β, H γ, and λ 5100 Å continuum light curves to discern the primary source of continuum emission, either from the accretion disk or the jet, during different activity phases. Our findings underscore the dominance of jet emission in the continuum during flare-like events. We observed an approximately 80 day delay between the H β and continuum emissions, which we attribute to the spatial separation between the optical emission zone and the broad-line region. Near-zero delays between optical and near-infrared emissions suggest that the emitting regions within the jet are cospatial. Synchrotron self-Compton was identified as the primary mechanism for γ -ray emission during flares, supported by the minimal delay observed between optical/near-infrared emissions and γ -rays. Additionally, we found a delay of about 60 days between the leading optical/near-infrared emissions and X-rays, indicating that inverse Compton scattering within the jet predominantly drives X-ray emission. However, distinguishing between synchrotron self-Compton and external inverse Compton mechanism was not feasible. Shifts in the spectral index across the 15–230 GHz range corresponded with ejections from the radio core, suggesting changes in the physical conditions of the jet. [ABSTRACT FROM AUTHOR]

We present a comprehensive analysis of the broadband spectral energy distribution (SED) of the extreme high-energy peaked BL Lac source, 1ES 0229+200. Our study utilizes near-simultaneous data collected at various epochs between 2017 September and 2021 August (MJD 58119−59365) from different instruments, including AstroSat−UVIT, Soft X-ray focusing Telescope, LAXPC, Swift−UVOT, Fermi-LAT, and MAGIC. We investigate the one-zone synchrotron and synchrotron self-Compton (SSC) model, employing diverse particle distributions such as the log parabola, broken power law, power law with a maximum electron energy γ, energy-dependent diffusion (EDD), and energy-dependent acceleration (EDA) models to fit the broadband SED of the source. Our findings indicate that both peaks in the SED are well described by the one-zone SSC model across all particle distribution models. We estimate the jet power for different particle distributions. The estimated jet power for broken power law particle distributions is found to be on the order of 1047 (1044) erg s−1 for a minimum electron energy γ min ∼10 (104). However, for intrinsically curved particle energy distributions (e.g., log parabola, EDD, and EDA models), the estimated jet power is ∼1044 erg s−1. The SED fitting at five epochs enables us to explore the correlation between the derived spectral parameters of various particle distribution models. Notably, the observed correlations are inconsistent with the predictions in the power-law with a maximum γ model, although the EDD and EDA models yield the correlations as expected. Moreover, the estimated physical parameter values are consistent with the model assumptions. [ABSTRACT FROM AUTHOR]

We present periodicity search analyses on the long-term γ -ray light curve of the BL Lacertae object 4FGL J2139.4−4235 observed by the Fermi Large Area Telescope, over a period of more than 15 yr, from 2008 August 4 to 2023 December 10. To determine the quasiperiodic oscillation (QPO) behavior of 4FGL J2139.4−4235 in the 0.3–300 GeV energy range, we used four methods, namely the Lomb–Scargle periodogram, the weighted wavelet z-transform, the phase dispersion minimization, and the autoregressive integrated moving average model. A Monte Carlo simulation technique is used to evaluate the significance level of the QPO signal. Significant levels above 3.5 σ were detected in the γ -ray light curve at about 650 days QPO, which is presented throughout the observation period. Interestingly, there was some correlation between the three bands in the discrete correlation function method calculations, which may be an indication that the variability trends between the three bands are similar. We explore the possible physical models and show that a supermassive binary black hole system or a jet helical motion model seem to be reasonable explanations for the potential QPO behavior. [ABSTRACT FROM AUTHOR]

We report the analysis of ∼1 Ms of XMM-Newton observations of the rapidly accreting active galactic nucleus RE J1034+396. The 0.3–9 keV EPIC-pn spectra are well described by a model consisting of steep continuum emission from the corona accompanied by relativistically blurred reflection from a highly ionized accretion disk. The source is known to exhibit strong excess soft X-ray emission, which we show is well represented by thermal disk photons Comptonized by a warm plasma spanning the inner accretion flow. Additionally, the EPIC-pn data provide compelling evidence (Δ C ∼ 60 for four additional parameters) for the presence of an ultrafast outflow (UFO) with a line-of-sight velocity v / c = 0.30 7 − 0.005 + 0.001 , and an emission signature consistent with reflection of the corona from modestly ionized, outflowing gas. The simultaneous 0.5–2.5 keV RGS spectra show clear absorption lines. Modelling of these data confirms the presence of the UFO and constrains its equivalent hydrogen column density, log N H/(atom cm−2) = 21.7 − 0.2 + 0.1 . The RGS data also reveal at least two warm absorber components with a modest outflow velocity ( 168 0 − 50 + 40 km s−1). The measured properties and time evolution of the UFO in RE J1034+396 suggest that it is formed from collisionally ionized plasma, launched from the disk surface and accelerated by radiation pressure. The high terminal velocity and substantial absorbing column density imply that the outflow carries sufficient momentum and energy to transform its environment, being capable of driving out essentially all dust and gas it interacts with along the line of sight, even if the AGN were initially surrounded by a Compton-thick absorber. [ABSTRACT FROM AUTHOR]

The 3C 220.3 system is a rare case of a foreground narrow-line radio galaxy ("galaxy A," z A = 0.6850) lensing a background submillimeter galaxy (z SMG = 2.221). New spectra from MMT/Binospec confirm that the companion galaxy ("galaxy B") is part of the lensing system with z B = 0.6835. New three-color Hubble Space Telescope (HST) data reveal a full Einstein ring and allow a more precise lens model. The new HST images also reveal extended emission around galaxy A, and the spectra show extended [O ii ] emission with irregular morphology and complex velocity structure. All indications are that the two lensing galaxies are a gravitationally interacting pair. Strong [O ii ] emission from both galaxies A and B suggests current star formation, which could be a consequence of the interaction. This would indicate a younger stellar population than previously assumed and imply smaller stellar masses for the same luminosity. The improved lens model and expanded spectral energy distributions have enabled better stellar mass estimates for the foreground galaxies. The resulting dark matter fractions are ∼0.8, which are higher than previously calculated. Deeper Chandra imaging shows extended X-ray emission but no evidence for an X-ray point source associated with either galaxy. The detection of X-rays from the radio lobes of 3C 220.3 allows an estimate of ∼3 nT for the magnetic fields in the lobes, a factor of ∼3 below the equipartition fields, as is typical for radio galaxies. [ABSTRACT FROM AUTHOR]

We have performed wide-field, ultra-low-surface-brightness H α emission-line mapping around NGC 1068 with the newly commissioned Circumgalactic H α Spectrograph. NGC 1068 is notable for its active galactic nucleus, which globally ionizes gas in the disk and halo. Line-emitting diffuse ionized gas is distributed throughout the galactic disk and large-scale ionized filaments are found well beyond the disk, aligned with the cone angle of the central jet. We report the discovery of a new ribbon of ionized gas around NGC 1068 beyond even the known outer filamentary structure, located 20 kpc from the galaxy. The H α surface brightness of this ribbon is on the order of the bright telluric lines, ranging from 4 to 16 R, with fainter regions on the order of the sky background continuum. Unlike previous extended emission, the ribbon is not as well aligned with the current axis of the central jet. It is not associated with any galactic structure or known tidal features in the halo of NGC 1068, though it may originate from a larger distribution of unmapped neutral atomic or molecular gas in the halo. The morphology of the ribbon emission in H α is correlated with extended UV emission around NGC 1068. H α -to-UV flux ratios in the ribbon are comparable to extended emission-line ratios in the halos of NGC 5128, NGC 253, and M82. The H α excess in the ribbon gas suggests ionization by slow shocks or a mixture of in situ star formation and photoionization and collisional ionization processes. [ABSTRACT FROM AUTHOR]

We present an enhanced version of the publicly available Stripe 82X catalog (S82-XL), featuring a comprehensive set of 22,737 unique X-ray point sources identified with a significance ≳4 σ. This catalog is four times larger than the original Stripe 82X catalog, by including additional archival data from the Chandra and XMM-Newton telescopes. Now covering ∼54.8 deg2 of nonoverlapping sky area, the S82-XL catalog roughly doubles the area and depth of the original catalog, with limiting fluxes (half-area fluxes) of 3.4 × 10−16 (2.4 × 10−15), 2.9 × 10−15 (1.5 × 10−14), and 1.4 × 10−15 (9.5 × 10−15) erg s−1 cm−2 across the soft (0.5–2 keV), hard (2–10 keV), and full (0.5–10 keV) bands, respectively. S82-XL occupies a unique region of flux-area parameter space compared to other X-ray surveys, identifying sources with rest-frame luminosities from 1.2 × 1038 to 1.6 × 1047 erg s−1 in the 2–10 keV band (median X-ray luminosity, 7.2 × 1043 erg s−1), and spectroscopic redshifts up to z ∼ 6. By using hardness ratios, we derived the obscuration of active galactic nuclei (AGNs), obtaining a median value of log (N H / cm − 2) = 21.6 − 1.6 + 1.0 and an overall, obscured fraction ( log (N H / cm − 2) > 22 ) of ∼36.9%. S82-XL serves as a benchmark in X-ray surveys and, with its extensive multiwavelength data, is especially valuable for comprehensive studies of luminous AGNs. [ABSTRACT FROM AUTHOR]

We present a focused X-ray and multiwavelength study of the ultraluminous weak-line quasar (WLQ) SDSS J1521+5202, one of the few X-ray weak WLQs that is amenable to basic X-ray spectral and variability investigations. J1521+5202 shows striking X-ray variability during 2006–2023, by up to a factor of ≈32 in 0.5–2 keV flux, and our new 2023 Chandra observation caught it in its brightest X-ray flux state to date. Concurrent infrared/optical observations show only mild variability. The 2023 Chandra spectrum can be acceptably described by a power law with intrinsic X-ray absorption, and it reveals a nominal intrinsic level of X-ray emission relative to its optical/ultraviolet emission. In contrast, an earlier Chandra spectrum from 2013 shows apparent spectral complexity that is not well fit by a variety of models, including ionized absorption or standard Compton-reflection models. Overall, the observations are consistent with the thick-disk plus outflow model previously advanced for WLQs, where a nominal level of underlying X-ray emission plus variable absorption leads to the remarkable observed X-ray variability. In the case of J1521+5202, it appears likely that the outflow, and not the thick disk itself, lies along our line of sight and causes the X-ray absorption. [ABSTRACT FROM AUTHOR]

This paper delves into the complex relationship between business leadership, sustainability, and inclusivity, representing a step toward developing a more inclusive leadership approach to sustainable development that fosters shared power relations between business leaders and marginalized members of society. With environmental and social conditions worsening, it is urgent for corporations to move away from the neoliberal profit-maximization models advocated by Milton Friedman and instead prioritize humanity and the environment. This shift requires a fundamental restructuring of businesses to move beyond profit maximization and address societal power imbalances by including all stakeholders. Our inclusive leadership for sustainable development framework, rooted in symbolic interactionism, offers a holistic lens for including marginalized groups. At the microlevel, it focuses on business leaders' personas, characterized by pro-demographic diversity and biodiversity, cognitive complexity for sustainable development, and social empathy, which can potentially create a macro-level impact. These characteristics, accompanied by macro perspectives toward repurposing corporations away from neoliberalism, would be a step forward in cultivating shared power dynamics between business leaders and marginalized communities for the betterment of society. [ABSTRACT FROM AUTHOR]

We observed the Seyfert 1 galaxy Mrk 817 during an intensive multiwavelength reverberation mapping campaign for 16 months. Here, we examine the behavior of narrow UV absorption lines seen in the Hubble Space Telescope/Cosmic Origins Spectrograph spectra, both during the campaign and in other epochs extending over 14 yr. We conclude that, while the narrow absorption outflow system (at −3750 km s−1 with FWHM = 177 km s−1) responds to the variations of the UV continuum as modified by the X-ray obscurer, its total column density (log N H = 19.5 − 0.13 + 0.61 cm−2) did not change across all epochs. The adjusted ionization parameter (scaled with respect to the variations in the hydrogen-ionizing continuum flux) is log U H = −1.0 − 0.3 + 0.1 . The outflow is located at a distance smaller than 38 pc from the central source, which implies a hydrogen density of n H > 3000 cm−3. The absorption outflow system only covers the continuum emission source and not the broad emission line region, which suggests that its transverse size is small (< 1016 cm), with potential cloud geometries ranging from spherical to elongated along the line of sight. [ABSTRACT FROM AUTHOR]

Jetted active galactic nuclei (AGN) hosting extended photoionized nebulae provide us with a unique view of the timescales associated with AGN activity. Here, we present a new green bean galaxy at z = 0.304458 ± 0.000007 with large-scale jet-induced radio emission. The spectral energy distributions of the radio components show steep spectral indices (α = −0.85 to −0.92 for the extended regions, and α = −1.02 for the faint radio core), and spectral age modeling of the extended radio emission indicates that the lobes are >6 Myr old. It is unclear whether the jet is active, or is a remnant with an off-time of 2–3 Myr. Several detached clouds lie around the host galaxy up to 37.8 kpc away from the nucleus, and their ionization profile indicates a decline (∼2 dex) in the AGN ionizing photon production over the past ∼0.15 Myr. Furthermore, we measure a blueshift for one of the clouds that is spatially coincident with the path of the radio jet. The cloud is likely illuminated by the photoionizing AGN, and potentially underwent an interaction with the relativistic jet. Our multiwavelength analysis suggests that RGB1 was in a phase of jet production prior to the radiatively efficient accretion phase traced by the detached cloud emission. It is unclear whether RGB1 transitioned into a low-excitation radio galaxy or an inactive galaxy over the past ∼0.15 Myr, or whether the extended radio and optical emission trace distinct accretion phases that occurred in succession. [ABSTRACT FROM AUTHOR]

The Next Generation Deep Extragalactic Exploratory Public (NGDEEP) survey program was designed specifically to include Near Infrared Slitless Spectroscopic observations (NGDEEP-NISS) to detect multiple emission lines in as many galaxies as possible and across a wide redshift range using the Near Infrared Imager and Slitless Spectrograph. We present early results obtained from the first set of observations (Epoch 1, 50% of the allocated orbits) of this program (NGDEEP-NISS1). Using a set of independently developed calibration files designed to deal with a complex combination of overlapping spectra, multiple position angles, and multiple cross filters and grisms, in conjunction with a robust and proven algorithm for quantifying contamination from overlapping dispersed spectra, NGDEEP-NISS1 has achieved a 3 σ sensitivity limit of 2 × 10−18 erg s−1 cm−2. We demonstrate the power of deep wide field slitless spectroscopy (WFSS) to characterize the star formation rates, and metallicity ([O iii ]/H β), and dust content, of galaxies at 1 < z < 3.5. The latter showing intriguing initial results on the applicability and assumptions made regarding the use of Case B recombination. Further, we identify the presence of active galactic nuclei and infer the mass of their supermassive black holes using broadened restframe Mg ii and H β emission lines. The spectroscopic results are then compared with the physical properties of galaxies extrapolated from fitting spectral energy distribution models to photometry alone. The results clearly demonstrate the unique power and efficiency of WFSS at near-infrared wavelengths over other methods to determine the properties of galaxies across a broad range of redshifts. [ABSTRACT FROM AUTHOR]

Case: We present a 17-year-old male patient with an initially missed posterior sternoclavicular fracture dislocation who presented with symptoms related to thrombotic emboli arising from a pseudoaneurysm. He was treated 6 weeks after injury with a figure-of-eight tendon allograft repair with good clinical outcomes. Conclusion: This is a unique presentation that highlights the significant risk of a missed diagnosis, life-threatening complications that may ensue, and biomechanically superior surgical intervention. [ABSTRACT FROM AUTHOR]

Isolated 17,20-lyase deficiency (ILD) is a partial form of 17α-hydroxylase/17,20-lyase deficiency that typically presents with infertility and lack of pubertal development. Successful live births have been achieved using assisted reproductive techniques. We present a case of spontaneous pregnancy in an 18-year-old female with ILD without reproduction treatments or glucocorticoid use. She presented to our clinic with absence of pubarche and oligomenorrhea and had typical external genitalia and complete breast development. Follicular phase progesterone and estradiol were within reference values, and androgen levels were undetectable. Corticosterone was increased, and cortisol responded partially to the ACTH-stimulation test. This profile raised a suspicion for ILD, which was confirmed by the finding of the homozygous p.R347H variant in the CYP17A1 gene. Sex steroid replacement and glucocorticoid use during stress were prescribed. She returned 2 years later 20 weeks pregnant. Her gestation was uneventful, and a full-term healthy male was born. This phenomenon could be partially explained by sufficient estrogen synthesis via residual 17,20-lyase enzymatic activity. Intermittent estradiol use may have favored uterine development and fine-tuned the pituitary-gonadal axis rhythm. Normal progesterone levels may have permitted an adequate endometrial "implantation window" without glucocorticoid use. Finally, elevated corticosterone may have compensated for the partial cortisol deficiency. [ABSTRACT FROM AUTHOR]

The Photometric objects Around Cosmic webs (PAC) approach developed in Xu et al. has the advantage of making full use of spectroscopic and deeper photometric surveys. With the merits of PAC, the excess surface density n ¯ 2 w p of neighboring galaxies can be measured down to stellar mass 1010.80 M ⊙ around quasars at redshift 0.8 < z s < 1.0, with the data from the Sloan Digital Sky Survey IV extended Baryon Oscillation Spectroscopic Survey and the Dark Energy Spectroscopic Instrument Legacy Imaging Surveys. We find that n ¯ 2 w p generally increases quite steeply with the decrease of the separation. Using the subhalo abundance-matching method, we can accurately model the n ¯ 2 w p both on small and large scales. We show that the steep increase of n ¯ 2 w p toward the quasars requires that a large fraction f sate = 0.29 − 0.06 + 0.05 of quasars should be satellites in massive halos, and we find that this fraction measurement is insensitive to the assumptions of our modeling. This high satellite fraction indicates that the subhalos have nearly the same probability of hosting quasars as the halos for the same (infall) halo mass and that the large-scale environment has negligible effect on the quasar activity. We show that even with this high satellite fraction, each massive halo on average does not host more than one satellite quasar, due to the sparsity of quasars. [ABSTRACT FROM AUTHOR]

It is commonly accepted that outflows from the central regions of quasars play a substantial role in regulating the global properties of the host galaxy. These outflows are typically detected through blueshifted absorption lines. However, the question remains whether outflows observed with different absorption line types indeed reflect the same environmental or evolutionary stage of the host galaxy. In this study, we use the Sloan Digital Sky Survey quasar catalog and employ the flux ratio of [O II ] and [Ne V] emission lines as indicators to compare star formation rates (SFRs) within host galaxies of quasars exhibiting various outflow absorption line types: low-ionization broad absorption line (LoBAL), low-ionization Mini-BAL (LoMini-BAL), low-ionization narrow absorption line (LoNAL), high-ionization broad absorption line (HiBAL), high-ionization Mini-BAL (HiMini-BAL), and high-ionization narrow absorption line (HiNAL). Our findings indicate that the SFR of LoMini-BAL quasars is comparable to that of LoNAL quasars, somewhat less than that of LoBAL quasars, but markedly greater than that of HiBAL quasars. Furthermore, the SFR of HiMini-BAL quasars mirrors that of HiNAL or Non-abs (no associated absorption lines) quasars, but is significantly higher than that of HiBAL quasars. If we consider that differing absorption line types are indicative of the quasar evolution stage, our results propose an inclusive evolution sequence: LoBALs evolve into LoMini-BALs/LoNALs, then progress to HiBALs, and ultimately morph into HiMini-BALs/HiNALs/Non-abs. Concomitantly, the SFR within the host galaxies of quasars appears to decline noticeably nearing the LoNAL phase's end and rejuvenates before the HiMini-BAL phase. [ABSTRACT FROM AUTHOR]

Quenching of star formation in the central galaxies of cosmological halos is thought to result from energy released as gas accretes onto a supermassive black hole. The same energy source also appears to lower the central density and raise the cooling time of baryonic atmospheres in massive halos, thereby limiting both star formation and black hole growth, by lifting the baryons in those halos to greater altitudes. One predicted signature of that feedback mechanism is a nearly linear relationship between the central black hole's mass (M BH) and the original binding energy of the halo's baryons. We present the increasingly strong observational evidence supporting a such a relationship, showing that it extends up to halos of mass M halo ∼ 1014 M ⊙. We then compare current observational constraints on the M BH– M halo relation with numerical simulations, finding that black hole masses in IllustrisTNG appear to exceed those constraints at M halo < 1013 M ⊙ and that black hole masses in EAGLE fall short of observations at M halo ∼ 1014 M ⊙. A closer look at IllustrisTNG shows that quenching of star formation and suppression of black hole growth do indeed coincide with black hole energy input that lifts the halo's baryons. However, IllustrisTNG does not reproduce the observed M BH– M halo relation because its black holes gain mass primarily through accretion that does not contribute to baryon lifting. We suggest adjustments to some of the parameters in the IllustrisTNG feedback algorithm that may allow the resulting black hole masses to reflect the inherent links between black hole growth, baryon lifting, and star formation among the massive galaxies in those simulations. [ABSTRACT FROM AUTHOR]

Accreting supermassive black holes (SMBHs) located at the centers of galaxies are typically surrounded by large quantities of gas and dust. The structure and evolution of this circumnuclear material can be studied at different wavelengths, from the submillimeter to the X-ray. Recent X-ray studies have shown that the covering factor of the obscuring material tends to decrease with increasing Eddington ratio, likely due to radiative feedback on dusty gas. Here we study a sample of 549 nearby (z ≲ 0.1) hard X-ray (14–195 keV) selected nonblazar active galactic nuclei (AGN) and use the ratio between the AGN infrared and bolometric luminosity as a proxy of the covering factor. We find that, in agreement with what has been found by X-ray studies of the same sample, the covering factor decreases with increasing Eddington ratio. We also confirm previous findings that showed that obscured AGN typically have larger covering factors than unobscured sources. Finally, we find that the median covering factors of AGN located in different regions of the column density–Eddington ratio diagram are in good agreement with what would be expected from a radiation-regulated growth of SMBHs. [ABSTRACT FROM AUTHOR]

Dynamical perturbations from supermassive black hole (SMBH) binaries can increase the rates of tidal disruption events (TDEs). However, most previous work focuses on TDEs from the heavier black hole in the SMBH binary (SMBHB) system. In this work, we focus on the lighter black holes in SMBHB systems and show that they can experience a similarly dramatic increase in their TDE rate due to perturbations from a more massive companion. While the increase in TDEs around the more massive black hole is mostly due to chaotic orbital perturbations, we find that, around the smaller black hole, the eccentric Kozai–Lidov mechanism is dominant and capable of producing a comparably large number of TDEs. In this scenario, the mass derived from the light curve and spectra of TDEs caused by the lighter SMBH companion is expected to be significantly smaller than the SMBH mass estimated from galaxy scaling relations, which are dominated by the more massive companion. This apparent inconsistency can help find SMBHB candidates that are not currently accreting as active galactic nuclei and that are at separations too small for them to be resolved as two distinct sources. In the most extreme cases, these TDEs provide us with the exciting opportunity to study SMBHBs in galaxies where the primary SMBH is too massive to disrupt Sun-like stars. [ABSTRACT FROM AUTHOR]

Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder with a related enzyme deficiency involved in the adrenal corticosteroid synthesis pathway due to genetic mutations. 17α-hydroxylase deficiency(17α-OHD) is a rare form of CAH. Herein, we reported clinical data on diagnosis and treatment regimens for a 17α-hydroxylase-deficient patient. A 24-year-old female patient was admitted to the hospital with limb numbness for 7 days and sudden limb weakness. Full laboratory and radio-imaging investigations showed hypokalemia and abdominal occupation. Abnormal rhythm of cortisol(Cor) and adrenocorticotrophic hormone (ACTH)was observed. The diagnosis was confirmed by molecular mutation detection, which showed a homozygous mutation of c.987del in the 17-hydroxylase/17,20-lyase deficiency (17OHD) lease-related CYP17A1 from both biological parents. The patient was treated with prednisone acetate and estradiol valerate. After one year of treatment with predisoone acetate and estradiol valerate, the patient had normal menstruation, increased blood potassium, estradiol and 24h-UFC, and decreased ACTH level. There is no significant change in large adrenal hyperplasia lesions although sexual characteristics and menstrual cycles have recovered. Through this case and literature review, it can be concluded that CAH with 17α-OHD can be diagnosed according to the genetic detection. [ABSTRACT FROM AUTHOR]

We examine the quenching characteristics of 328 isolated dwarf galaxies 10 8 < M star / M ⊙ < 10 10 within the Romulus25 cosmological hydrodynamic simulation. Using mock-observation methods, we identify isolated dwarf galaxies with quenched star formation and make direct comparisons to the quenched fraction in the NASA Sloan Atlas (NSA). Similar to other cosmological simulations, we find a population of quenched, isolated dwarf galaxies below M star < 109 M ⊙ not detected within the NSA. We find that the presence of massive black holes (MBHs) in Romulus25 is largely responsible for the quenched, isolated dwarfs, while isolated dwarfs without an MBH are consistent with quiescent fractions observed in the field. Quenching occurs between z = 0.5–1, during which the available supply of star-forming gas is heated or evacuated by MBH feedback. Mergers or interactions seem to play little to no role in triggering the MBH feedback. At low stellar masses, M star ≲ 109.3 M ⊙, quenching proceeds across several Gyr as the MBH slowly heats up gas in the central regions. At higher stellar masses, M star ≳ 109.3 M ⊙, quenching occurs rapidly within 1 Gyr, with the MBH evacuating gas from the central few kpc of the galaxy and driving it to the outskirts of the halo. Our results indicate the possibility of substantial star formation suppression via MBH feedback within dwarf galaxies in the field. On the other hand, the apparent overquenching of dwarf galaxies due to MBH suggests that higher-resolution and/or better modeling is required for MBHs in dwarfs, and quenched fractions offer the opportunity to constrain current models. [ABSTRACT FROM AUTHOR]

17,18-Epoxyeicosatetraenoic acid (17,18-EEQ) and 19,20-epoxydocosapentaenoic acid (19,20-EDP) are bioactive epoxides produced from n-3 polyunsaturated fatty acid eicosapentaenoic acid and docosahexaenoic acid, respectively. However, these epoxides are quickly metabolized into less active diols by soluble epoxide hydrolase (sEH). We have previously demonstrated that an sEH inhibitor, t-TUCB, decreased serum triglycerides (TG) and increased lipid metabolic protein expression in the brown adipose tissue (BAT) of diet-induced obese mice. This study investigates the preventive effects of t-TUCB (T) alone or combined with 19,20-EDP (T + EDP) or 17,18-EEQ (T + EEQ) on BAT activation in the development of diet-induced obesity and metabolic disorders via osmotic minipump delivery in mice. Both T + EDP and T + EEQ groups showed significant improvement in fasting glucose, serum triglycerides, and higher core body temperature, whereas heat production was only significantly increased in the T + EEQ group. Moreover, both the T + EDP and T + EEQ groups showed less lipid accumulation in the BAT. Although UCP1 expression was not changed, PGC1α expression was increased in all three treated groups. In contrast, the expression of CPT1A and CPT1B, which are responsible for the rate-limiting step for fatty acid oxidation, was only increased in the T + EDP and T + EEQ groups. Interestingly, as a fatty acid transporter, CD36 expression was only increased in the T + EEQ group. Furthermore, both the T + EDP and T + EEQ groups showed decreased inflammatory NFκB signaling in the BAT. Our results suggest that 17,18-EEQ or 19,20-EDP combined with t-TUCB may prevent high-fat diet-induced metabolic disorders, in part through increased thermogenesis, upregulating lipid metabolic protein expression, and decreasing inflammation in the BAT.

Spectroscopic studies of extreme-ionization galaxies (EIGs) are critical to our understanding of exotic systems throughout cosmic time. These EIGs exhibit spectral features requiring >54.42 eV photons: the energy needed to ionize helium into He2+ fully and emit He ii recombination lines. Spectroscopic studies of EIGs can probe exotic stellar populations or accretion onto intermediate-mass black holes (∼102–105 M ⊙), which are the possibly key contributors to the reionization of the Universe. To facilitate the use of EIGs as probes of high-ionization systems, we focus on ratios constructed from several rest-frame UV/optical emission lines: [O iii ] λ 5008, H β, [Ne iii ] λ 3870, [O ii ] λ λ 3727, 3729, and [Ne v ] λ 3427. These lines probe the relative intensity at energies of 35.12, 13.62, 40.96, 13.62, and 97.12 eV, respectively, covering a wider range of ionization than traced by other common rest-frame UV/optical techniques. We use the ratios of these lines ([Ne v ]/[Ne iii ] ≡ Ne53, [O iii ]/H β, and [Ne iii ]/[O ii ]), which are nearby in wavelength, mitigating the effects of dust attenuation and uncertainties in flux calibration. We make predictions from photoionization models constructed from Cloudy that use a broad range of stellar populations and black hole accretion models to explore the sensitivity of these line ratios to changes in the ionizing spectrum. We compare our models to observations from the Hubble Space Telescope and JWST of galaxies with strong high-ionization emission lines at z ∼ 0, z ∼ 2, and 5 < z < 8.5. We show that the Ne53 ratio can separate galaxies with ionization from "normal" stellar populations from those with active galactic nuclei and even "exotic" Population III models. We introduce new selection methods to identify galaxies with photoionization driven by Population III stars or intermediate-mass black hole accretion disks that could be identified in upcoming high-redshift spectroscopic surveys. [ABSTRACT FROM AUTHOR]

PG 1448+273 is a luminous, nearby (z = 0.0645), narrow-line Seyfert 1 galaxy, which likely accretes close to the Eddington limit. XMM-Newton observations of PG 1448+273 in 2017 revealed the presence of an ultrafast outflow, as seen through its blueshifted iron K absorption profile, with an outflow velocity of about 0.1 c. Here, the first NuSTAR observation of PG 1448+273, performed in 2022 and coordinated with XMM-Newton, is presented, which shows remarkable variability of its ultrafast outflow. The average count rate is a factor of 2 lower during the last 60 ks of the NuSTAR observation, where a much faster component of the ultrafast outflow was detected with a terminal velocity of 0.26 ± 0.04 c. This is significantly faster than the outflow component that was initially detected in 2017, when overall PG 1448+273 was observed at a lower X-ray flux, and which implies an order of magnitude increase in the wind kinetic power between the 2017 and 2022 epochs. Furthermore, the rapid variability of the ultrafast outflow in 2022, on timescales down to 10 ks, suggests we are viewing through a highly inhomogeneous disk wind in PG 1448+273, where the passage of a denser wind clump could account for the increase in obscuration in the last 60 ks of the NuSTAR observation. [ABSTRACT FROM AUTHOR]

We present a study of the [O iii ] λ 5007 line profile in a subsample of eight active galactic nuclei (AGNs) and six non-AGNs in the optically selected green valley at z < 0.5 using long-slit spectroscopic observations obtained with the 11 m Southern African Large Telescope. Gaussian decomposition of the line profile was performed to study its different components. We observe that the AGN profiles are more complex than the non-AGN ones. In particular, in most AGNs (5/8) we detect a blue wing of the line. We derive the FWHM velocities of the wing and systemic component, and find that the AGNs show higher FWHM velocities than the non-AGNs in their core component. We also find that the AGNs show blue wings with a median velocity width of approximately 600 km s−1, and a velocity offset from the core component in the range −90 to −350 km s−1, in contrast to the non-AGN galaxies, where we do not detect blue wings in any of their [O iii ] λ 5007 line profiles. Using the spatial information in our spectra, we show that at least three of the outflow candidate galaxies have centrally driven gas outflows extending across the whole galaxy. Moreover, these are also the galaxies which are located on the main sequence of star formation, raising the possibility that the AGNs in our sample are influencing the star formation of their host galaxies (such as positive feedback). This is in agreement with our previous work where we studied the star formation, morphology, and stellar population properties of a sample of green valley AGNs and non-AGN galaxies. [ABSTRACT FROM AUTHOR]

We report the results of Atacama Large Millimeter/submillimeter Array (ALMA) 1–2 kpc resolution, three rotational transition-line (J = 2–1, J = 3–2, and J = 4–3) observations of multiple dense molecular gas tracers (HCN, HCO+, and HNC) for 10 nearby (ultra)luminous infrared galaxies ((U)LIRGs). Following the matching of beam sizes to 1–2 kpc for each (U)LIRG, the high- J -to-low- J transition-line flux ratios of each molecule and the emission-line flux ratios of different molecules at each J transition are derived. We conduct RADEX non-LTE model calculations and find that, under a wide range of gas density and kinetic temperature, the observed HCN-to-HCO+ flux ratios in the overall (U)LIRGs are naturally reproduced with enhanced HCN abundance compared to HCO+. Thereafter, molecular gas properties are constrained primarily through the use of HCN and HCO+ data and the adoption of fiducial values for the HCO+ column density and HCN-to-HCO+ abundance ratio. We quantitatively confirm the following: (i) molecular gas at the (U)LIRGs' nuclei is dense (≳103–4 cm−3) and warm (≳100 K), (ii) the molecular gas density and temperature in nine ULIRGs' nuclei are significantly higher than those of one LIRG's nucleus, (iii) molecular gas in starburst-dominated sources tends to be less dense and cooler than ULIRGs with luminous AGN signatures. For six selected sources, we also apply a Bayesian approach by freeing all parameters and support the above main results. Our ALMA 1–2 kpc resolution, multiple transition-line data of multiple molecules are a very powerful tool for scrutinizing the properties of molecular gas concentrated around luminous energy sources in nearby (U)LIRGs' nuclei. [ABSTRACT FROM AUTHOR]

Cluster galaxies are subject to the ram pressure exerted by the intracluster medium, which can perturb or even strip away their gas while leaving the stars undisturbed. We model the distribution and kinematics of the stars and the molecular gas in four late-type cluster galaxies (JO201, JO204, JO206, and JW100), which show tails of atomic and ionized gas indicative of ongoing ram pressure stripping. We analyze MUSE@VLT data and CO data from the Atacama Large Millimeter Array searching for signatures of radial gas flows, ram pressure stripping, and other perturbations. We find that all galaxies, with the possible exception of JW100, host stellar bars. Signatures of ram pressure are found in JO201 and JO206, which also shows clear indications of ongoing stripping in the molecular disk outskirts. The stripping affects the whole molecular gas disk of JW100. The molecular gas kinematics in JO204 is instead dominated by rotation rather than ram pressure. We also find indications of enhanced turbulence of the molecular gas compared to field galaxies. Large-scale radial flows of molecular gas are present in JO204 and JW100, but more uncertain in JO201 and JO206. We show that our sample follows the molecular gas mass–size relation, confirming that it is essentially independent of environment even for the most extreme cases of stripping. Our findings are consistent with the molecular gas being affected by the ram pressure on different timescales and less severely than the atomic and ionized gas phases, likely because the molecular gas is denser and more gravitationally bound to the galaxy. [ABSTRACT FROM AUTHOR]

We combine our dynamical modeling black-hole mass measurements from the Lick AGN Monitoring Project 2016 sample with measured cross-correlation time lags and line widths to recover individual scale factors, f, used in traditional reverberation-mapping analyses. We extend our sample by including prior results from Code for AGN Reverberation and Modeling of Emission Lines (caramel) studies that have utilized our methods. Aiming to improve the precision of black-hole mass estimates, as well as uncover any regularities in the behavior of the broad-line region (BLR), we search for correlations between f and other AGN/BLR parameters. We find (i) evidence for a correlation between the virial coefficient log 10 (f mean , σ) and black-hole mass, (ii) marginal evidence for a similar correlation between log 10 (f rms , σ) and black-hole mass, (iii) marginal evidence for an anticorrelation of BLR disk thickness with log 10 (f mean , FWHM) and log 10 (f rms , FWHM) , and (iv) marginal evidence for an anticorrelation of inclination angle with log 10 (f mean , FWHM) , log 10 (f rms , σ) , and log 10 (f mean , σ). Last, we find marginal evidence for a correlation between line-profile shape, when using the root-mean-square spectrum, log 10 (FWHM / σ) rms , and the virial coefficient, log 10 (f rms , σ) , and investigate how BLR properties might be related to line-profile shape using caramel models. [ABSTRACT FROM AUTHOR]

We present reverberation mapping measurements for the prominent ultraviolet broad emission lines of the active galactic nucleus Mrk 817 using 165 spectra obtained with the Cosmic Origins Spectrograph on the Hubble Space Telescope. Our ultraviolet observations are accompanied by X-ray, optical, and near-infrared observations as part of the AGN Space Telescope and Optical Reverberation Mapping Program 2 (AGN STORM 2). Using the cross-correlation lag analysis method, we find significant correlated variations in the continuum and emission-line light curves. We measure rest-frame delayed responses between the far-ultraviolet continuum at 1180 Å and Ly α λ 1215 Å ( 10.4 − 1.4 + 1.6 days), N v λ 1240 Å ( 15.5 − 4.8 + 1.0 days), Si iv + ]O iv λ 1397 Å ( 8.2 − 1.4 + 1.4 days), C iv λ 1549 Å ( 11.8 − 2.8 + 3.0 days), and He ii λ 1640 Å ( 9.0 − 1.9 + 4.5 days) using segments of the emission-line profile that are unaffected by absorption and blending, which results in sampling different velocity ranges for each line. However, we find that the emission-line responses to continuum variations are more complex than a simple smoothed, shifted, and scaled version of the continuum light curve. We also measure velocity-resolved lags for the Ly α and C iv emission lines. The lag profile in the blue wing of Ly α is consistent with virial motion, with longer lags dominating at lower velocities, and shorter lags at higher velocities. The C iv lag profile shows the signature of a thick rotating disk, with the shortest lags in the wings, local peaks at ±1500 km s−1, and a local minimum at the line center. The other emission lines are dominated by broad absorption lines and blending with adjacent emission lines. These require detailed models, and will be presented in future work. [ABSTRACT FROM AUTHOR]

We analyze a sample of 25 [Ne v ] (λ 3426) emission-line galaxies at 1.4 < z < 2.3 using Hubble Space Telescope/Wide Field Camera 3 G102 and G141 grism observations from the CANDELS Ly α Emission at Reionization (CLEAR) survey. [Ne v ] emission probes extremely energetic photoionization (creation potential of 97.11 eV) and is often attributed to energetic radiation from active galactic nuclei (AGNs), shocks from supernovae, or an otherwise very hard ionizing spectrum from the stellar continuum. In this work, we use [Ne v ] in conjunction with other rest-frame UV/optical emission lines ([O ii ] λ λ 3726, 3729, [Ne iii ] λ 3869, H β, [O iii ] λ λ 4959, 5007, H α +[N ii ] λ λ 6548, 6583, [S ii ] λ λ 6716, 6731), deep (2–7 Ms) X-ray observations (from Chandra), and mid-infrared imaging (from Spitzer) to study the origin of this emission and to place constraints on the nature of the ionizing engine. The majority of the [Ne v ]-detected galaxies have properties consistent with ionization from AGNs. However, for our [Ne v ]-selected sample, the X-ray luminosities are consistent with local (z ≲ 0.1) X-ray-selected Seyferts, but the [Ne v ] luminosities are more consistent with those from z ∼ 1 X-ray-selected QSOs. The excess [Ne v ] emission requires either reduced hard X-rays or a ∼0.1 keV excess. We discuss possible origins of the apparent [Ne v ] excess, which could be related to the "soft (X-ray) excess" observed in some QSOs and Seyferts and/or be a consequence of a complex/anisotropic geometry for the narrow-line region, combined with absorption from a warm, relativistic wind ejected from the accretion disk. We also consider implications for future studies of extreme high-ionization systems in the epoch of reionization (z ≳ 6) with the James Webb Space Telescope. [ABSTRACT FROM AUTHOR]

PKS 2005−489 is a well-known, bright southern BL Lac object that has been detected up to TeV energies. In a low-flux state it exhibits the expected multiwavelength double-peaked spectrum in the radio− γ -ray band. The high-flux state shows extreme flux variations in the X-ray band with a hardening as well as a peculiar curved feature in the spectrum. Thus far, PKS 2005−489 is the only source to exhibit such a feature. To study the X-ray variability further, we obtained the first hard X-ray spectrum of the source with the Nuclear Spectroscopic Telescope Array. We compare quasi-simultaneous radio, optical, UV, soft and hard X-ray, and γ -ray data of PKS 2005−489 to archival data in order to study its broadband behavior. We find a very consistent quiet state in the spectral energy distribution, with little variation in spectral shape or flux between the 2012 and 2020 data. A possible explanation for the peculiar X-ray spectrum in the flaring state is an additional component in the jet, possibly accelerated via magnetic reconnection, that is not co-spatial to the low-flux state emission region. [ABSTRACT FROM AUTHOR]