1. Ectopic ACTH Syndrome Due to Occult Bronchial Carcinoid
- Author
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Salvatore Maria Corsello, Vittoria Rufini, Alfredo Pontecorvi, Rosa Maria Paragliola, Rosa Maria Lovicu, Giovanni Simonetti, and Danilo Fintini
- Subjects
Adult ,Male ,endocrine system ,medicine.medical_specialty ,Bilateral inferior petrosal sinus sampling ,medicine.medical_treatment ,Octreotide ,Carcinoid Tumor ,Diagnosis, Differential ,Bronchial carcinoid ,Cushing syndrome ,Settore MED/36 - Diagnostica per Immagini e Radioterapia ,Bronchoscopy ,Bronchial neoplasm ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,Cushing Syndrome ,Tomography, Emission-Computed, Single-Photon ,Transsphenoidal surgery ,medicine.diagnostic_test ,business.industry ,Bronchial Neoplasms ,Indium Radioisotopes ,Virtual bronchoscopy ,General Medicine ,Pentetic Acid ,111 In-Octreoscan ,Ectopic Cushing syndrome ,SPECT-CT ,medicine.disease ,Occult ,Cushing Disease ,ACTH Syndrome, Ectopic ,Radiology ,Radiopharmaceuticals ,Differential diagnosis ,Tomography, X-Ray Computed ,business ,medicine.drug - Abstract
Cushing syndrome (CS) is certainly one of the most challenging endocrine disorders. The greatest problem involves the differentiation between Cushing disease and ectopic ACTH syndrome. We report a patient with ACTH-dependent CS who elsewhere underwent unsuccessful transsphenoidal surgery for a pituitary microadenoma. In our institution, high resolution CT didn't show any chest tumor but laboratory data were consistent with ectopic ACTH secretion.Only In-111 Octreoscan, integrated with SPECT-CT and virtual bronchoscopy, allowed the diagnosis of ectopic Cushing syndrome due to occult bronchial carcinoid. Successful surgery was then performed. © 2009 by Lippincott Williams & Wilkins.
- Published
- 2009
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