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13 results on '". Andorsky, D. J"'

1. P1156: MAGNIFY PHASE 3B STUDY OF LENALIDOMIDE + RITUXIMAB (R2) FOLLOWED BY MAINTENANCE IN RELAPSED/REFRACTORY INDOLENT NON-HODGKIN LYMPHOMA: COMPLETE INDUCTION PHASE ANALYSIS

Author

Lansigan, F., primary, Andorsky, D. J., additional, Coleman, M., additional, Yacoub, A., additional, Melear, J. M., additional, Fanning, S. R., additional, Kolibaba, K. S., additional, Reynolds, C., additional, Nowakowski, G. S., additional, Gharibo, M., additional, Ahn, J. R., additional, Li, J., additional, Rummel, M. J., additional, and Sharman, J. P., additional

Published
2022
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2. P1100: BRUIN MCL-321: A PHASE 3 OPEN-LABEL, RANDOMIZED STUDY OF PIRTOBRUTINIB VS INVESTIGATOR CHOICE OF BTK INHIBITOR IN PATIENTS WITH PREVIOUSLY TREATED, BTK INHIBITOR NAÏVE MCL (TRIAL IN PROGRESS)

Author

Eyre, T. A., primary, Shah, N. N., additional, Le Gouill, S., additional, Dreyling, M., additional, Vandenberghe, E., additional, Jurczak, W., additional, Wang, Y., additional, Cheah, C. Y., additional, Gandhi, M., additional, Chay, C., additional, Sharman, J. P., additional, Andorsky, D. J., additional, Yin, M., additional, Balbas, M., additional, Kherani, J., additional, and Wang, M. L., additional

Published
2022
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3. P1101: PIRTOBRUTINIB, A HIGHLY SELECTIVE, NON-COVALENT (REVERSIBLE) BTK INHIBITOR IN PREVIOUSLY TREATED MANTLE CELL LYMPHOMA: UPDATED RESULTS FROM THE PHASE 1/2 BRUIN STUDY

Author

Eyre, T. A., primary, Wang, M. L., additional, Shah, N. N., additional, Alencar, A. J., additional, Gerson, J. N., additional, Patel, M. R., additional, Fakhri, B., additional, Vandenberghe, E., additional, Jurczak, W., additional, Tan, X. N., additional, Lewis, K. L., additional, Fenske, T., additional, Wang, Y., additional, Coombs, C. C., additional, Flinn, I., additional, Lewis, D., additional, Le Gouill, S., additional, Gandhi, M., additional, Chay, C., additional, Palomba, M. L., additional, Woyach, J. A., additional, Pagel, J. M., additional, Lamanna, N., additional, Sharman, J. P., additional, Andorsky, D. J., additional, Cohen, J. B., additional, Barve, M. A., additional, Ghia, P., additional, Yin, M., additional, Zinzani, P. L., additional, Ujjani, C., additional, Koh, Y., additional, Izutsu, K., additional, Lech-Maranda, E., additional, Kherani, J., additional, Tam, C., additional, Sundaram, S., additional, Nair, B., additional, Tsai, D. E., additional, Balbas, M., additional, Mato, A. R., additional, and Cheah, C. Y., additional

Published
2022
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4. INDUCTION R2 FOLLOWED BY MAINTENANCE IN PATIENTS WITH RELAPSED/REFRACTORY MANTLE CELL LYMPHOMA: INTERIM ANALYSIS FROM THE PHASE 3B MAGNIFY STUDY

Author

Sharman, J. P., primary, Melear, J. M., additional, Yacoub, A., additional, Fanning, S. R., additional, Andorsky, D. J., additional, Nowakowski, G. S., additional, Rummel, M. J., additional, Lansigan, F., additional, Li, J., additional, Ahn, J. R., additional, Gharibo, M., additional, and Coleman, M., additional

Published
2021
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5. INDUCTION R 2 FOLLOWED BY MAINTENANCE IN PATIENTS WITH RELAPSED/REFRACTORY TRANSFORMED FOLLICULAR LYMPHOMA: INTERIM ANALYSIS FROM THE PHASE 3B MAGNIFY STUDY

Author

. Lansigan, F, primary, . Parameswaran, V, additional, . Yacoub, A, additional, . Reynolds, C. M, additional, . Shao, S. H, additional, . Moore, S. G, additional, . Coleman, M, additional, . Andorsky, D. J, additional, . Nowakowski, G. S, additional, . Rummel, M. J, additional, . Li, J, additional, . Ahn, J. R, additional, . Gharibo, M, additional, and . Sharman, J. P, additional

Published
2021
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13. Nutritional and other postoperative management of neonates with short bowel syndrome correlates with clinical outcomes.

Author

Andorsky DJ, Lund DP, Lillehei CW, Jaksic T, Dicanzio J, Richardson DS, Collier SB, Lo C, and Duggan C

Subjects
Adaptation, Physiological, Cholestasis epidemiology, Enteral Nutrition, Enterocolitis, Necrotizing therapy, Female, Food, Formulated, Humans, Infant, Newborn, Intestines abnormalities, Intestines physiology, Male, Milk, Human, Multivariate Analysis, Postoperative Care, Retrospective Studies, Risk Factors, Short Bowel Syndrome epidemiology, Short Bowel Syndrome surgery, Time Factors, Treatment Outcome, Parenteral Nutrition, Short Bowel Syndrome therapy
Abstract

Objective: To determine correlates of clinical outcomes in patients with short bowel syndrome (SBS)., Methods: Retrospective medical record review of neonates treated between 1986 and 1998 who met our criteria for SBS: dependence on parenteral nutrition (PN) for at least 90 days after surgical therapy for congenital or acquired intestinal diseases., Results: Thirty subjects with complete data were identified; 13 (43%) had necrotizing enterocolitis, and 17 (57%)had intestinal malformations. Mean (SD) residual small bowel length was 83 (67) cm. Enteral feeding with breastmilk (r = -0.821) or an amino acid-based formula (r = -0.793) was associated with a shorter duration of PN, as were longer residual small bowel length (r = -0.475) and percentage of calories received enterally at 6 weeks after surgery(r = -0.527). Shorter time without diverting ileostomy or colostomy (r = 0.400), enteral feeding with a protein hydrolysate formula (r = -0.476), and percentage of calories received enterally at 6 weeks after surgery (r = -0.504) were associated with a lower peak direct bilirubin concentration. Presence of an intact ileocecal valve and frequency of catheter-related infections were not significantly correlated with duration of PN. In multivariate analysis, only residual small bowel length was a significant independent predictor of duration of PN, and only less time with a diverting ostomy was an independent predictor of peak direct bilirubin concentration., Conclusions: Although residual small bowel length remains an important predictor of duration of PN use in infants with SBS, other factors, such as use of breast milk or amino acid-based formula, may also play a role in intestinal adaptation. In addition, prompt restoration of intestinal continuity is associated with lowered risk of cholestatic liver disease. Early enteral feeding after surgery is associated both with reduced duration of PN and less cholestasis.

Published
2001
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