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【目的】探讨重组腺病毒介导的人TK-1和TIMP-1基因过表达对大鼠心肌梗死后的左室（LV）功能、炎症因子表达的影响及其机制。【方法】通过结扎Sprague-Dawley雄性大鼠冠脉左前降支诱导心肌梗死模型。观察假手术组（10只）、生理盐水组（13只）、对照病毒组（13只）、TK-1组（13只）、TIMP-1组（13只）、联合基因组（13只）的大鼠术后的心功能参数改变、心肌梗死面积、及各组大鼠基质金属蛋白酶-2（MMP-2）、基质金属蛋白酶-9（MMP-9）、核因子-κB（NF-κB）和巨噬细胞迁移抑制因子（MIF）的表达水平。【结果】与假手术组相比，对照病毒组大鼠的各项心功能参数（左室舒张期内径LVIDd、左室收缩期内径LVIDs、短轴缩短率FS、射血分数EF）差（P＜0.01），心肌梗死面积大（P＜0.01），心肌细胞凋亡指数高（P＜0.01），各炎症因子（NF-κB、MIF、MMP-2、MMP-9）的表达水平上升（P＜0.01）。与对照病毒组相比，单基因组或联合基因组的心功能改善明显；心肌梗死的面积明显减少；心肌细胞凋亡指数显著下降；炎症因子的表达明显下降。相比于单基因组，联合基因组各项指标改善更显著。【结论】hTK-1或hTIMP-1单基因过表达可改善大鼠心肌梗死后的心功能，抑制炎症因子表达与心肌细胞凋亡，联合基因过表达（hTK-1和hTIMP-1）呈协同效应、改善更显著，可能的机制为hTK-1或hTIMP-1均可部分抑制MIF/NF-κB/MMP-2/9炎症信号通路。

Tractors have been widely used for production in modern agriculture. But the tractor rollover can be a frequent accident in agricultural production at present. It is still lacking in the reliable theoretical and technical support to the tractor rollover, because of the abruptness and rapidity of the accident. In this review, the research achievements were firstly summarized on the mathematical description of tractor kinematics and rollover dynamics. A systematic analysis was made on the strengths and weaknesses of dynamic and kinematic modeling approaches on the rollover characteristics of tractors. According to the variability of field operation environments and the complexity of the tractor rollover, machine learning was also introduced to treat the complex force relationships and unknown disturbances during tractor operation. Secondly, the research progresses were reviewed on the tractor rollover mechanisms, in order to extract the influencing factors of rollover. Furthermore, it was recommended that the influencing factors of rollover should be classified and quantified to explore the specific mechanism under different rollover conditions. It was necessary to establish the complete characterization of the influencing factors of rollover. Thirdly, the design principles of rollover warning were incorporated with the active anti-rollover control systems. The rollover risks were systematically summarized to assess the anti-rollover systems. Tractor parameters also shared a significant impact on the assessment indicators of rollover risk. The most effective solutions were using cost-saving intelligent sensors and soft computing with machine learning. The active anti-rollover control system was significantly improved to solve the insufficient anti-rollover torque and control timeliness in the active anti-rollover control system. More control schemes should be proposed to combine the multiple rollover prevention actuators and the pre-perception of the environment. Fourthly, the summary was also made on the theoretical basis and technical achievements of rollover protection devices. A pre-regulatable actuator should be designed on the intelligent, automated, or foldable rollover protection device in the active anti-rollover control system. Lastly, the experimental means were summarized for the rollover mechanism analysis and theoretical verification. The platforms should be recommended with the function of data process and posture control. The hardware simulation platforms were also integrated with the different simulation software. The reason was that the current lateral stability platforms were unable to reconstruct the complexity environment, and then represent the complexity of the tractor variation in real time. Research priorities and directions of tractor anti-rollover and rollover protection were specifically predicted to provide basic research and product development in modern agriculture. [ABSTRACT FROM AUTHOR]

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Soil & Water Conservation (1009-2242) is the property of Institute of Soil & Water Conservation and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Applying blockchain technology to the cloud manufacturing platform (CMfg) endowed it with features such as decentralized resource management, distributed data storage, and platform robustness. However, during the implementation of service optimization composition, challenges are encountered, including the need for centralized resource scheduling, data entry dependence on the moment of block generation, and a lack of dynamic adaptability in the execution scheme. To address this, this paper proposed a solution in the form of cloud dual-chain oriented to service optimization composition. The cloud dualchain comprised a manufacturing service chain (MSC) and a process data chain (PDC). It segregated the management of service resources and composition scheme into distinct chains, allowing the CMfg to reconcile blockchain characteristics with real-world service collaboration needs. The manufacturing service within the cloud dual-chain was self-managed by the enterprise, and the MSC chain was formed by smart contracts based on task orders, balancing distributed and centralized management. The PDC, generated based on service composition, recorded process data in parallel. In case of service failure, a new service was invoked in the corresponding MSC node, updating the information in the PDC node to ensure dynamic adaptability of the execution plan. Experimental results demonstrate that cloud dual-chain facilitates flexible service management, distributed parallel entry of process data, and provides dynamic adaptability to execution scheme. Cloud dual-chain can effectively support the development of CMfg. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Chinese Institute of Food Science & Technology / Zhongguo Shipin Xuebao is the property of Journal of Chinese Institute of Food Science & Technology Periodical Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Xinjiang Agricultural Sciences is the property of Xinjiang Agricultural Sciences Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Contemporary Pediatrics is the property of Xiangya Medical Periodical Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Arteriosclerosis is the property of Chinese Journal of Arteriosclerosis Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Feed Research is the property of Editorial Board of Feed Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Anhui Agricultural Sciences is the property of Journal of Anhui Agricultural Sciences Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Engineering Science Research & Application is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The education on occupational safety is a key part of cultivation and education for nurses. This paper analyzed the occupational risks for nursing students and discussed the preventive measures, in order to strengthen the safety culture and increase the awareness of occupational risk among nursing students. (护士职业安全文化教育是护士培养和教育过程中的重要环节。本文分析实习护士在刚进入临床工作时面临的职业风险, 探讨预防措施, 以强化职业安全文化, 提高职业风险意识。)

Copyright of Journal of Anhui Agricultural Sciences is the property of Journal of Anhui Agricultural Sciences Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Mycosystema is the property of Mycosystema Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Beijing University of Technology is the property of Journal of Beijing University of Technology, Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Cancer Biotherapy is the property of Editorial Office of Chinese Journal of Cancer Biotherapy and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

To detect wheat regional trail lines with molecular markers and clarify favorable allele composition is conducive to the further precise improvement and utilization. Analyzing the problems in KASP marker detection will promote application in molecular breeding. In this study, using twenty-four advanced lines participated the 2021-2022 wheat dryland regional trial of Shandong province as materials, a total of 32 KASP markers associated with drought resistance and high yield were used to analyze the abnormal results in KASP marker detection and utilization of the favorable allele. The results indicated that the main reason for unknown genotypes was KASP reaction failure or non-specific amplification. The main reason for heterozygous results of mixed DNA samples was genotypic inconsistency among individuals, and the secondary reason was genotyping error. Among the 32 markers detected，the favorable allele detection rate of 14 KASP markers was above 83%, indicating that they were already efficiently applied in breeding programs, and the detection rate of the favorable alleles of 17 markers was below 50%. Among the 17 markers, the favorable alleles of the five markers including WRKY51-2B, AX-95025477-7B, SnRK2.4A3, TaMoc-2433, and NCED1 were not detected, indicating that the genes were applied less in breeding. Those less applied genes could be utilized through marker assisted selection for future genetic improvement. Among the 24 tested lines, HQ04 carried 20 favorable alleles which was the most and it could be used as a gene donor for breeding. There is still room for accurate and directive improvement of utilization rate of favorable alleles in wheat breeding through KASP marker-assisted selection. [ABSTRACT FROM AUTHOR]

Copyright of China Brewing is the property of China Brewing Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Engineering Management & Technology Discussion is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Cancer Research on Prevention & Treatment is the property of Cancer Research on Prevention & Treatment Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To compare the characteristics of gut microbiota and metabolic functions in patients with polycystic ovary syndrome（PCOS）, specifically focusing on the differences between obese and non-obese individuals. Methods Sixteen obese PCOS females（BMI≥28 kg/m²）, twelve non-obese PCOS females（BMI 18.5-23.9 kg/m²）, and fourteen healthy young females（BMI 18.5-23.9 kg/m²） were selected from June 2020 to June 2022 as the non-obese normal group. Additionally, six healthy but obese females（BMI ≥28 kg/m²） were included as the obese normal group. Blood and non-menstrual fecal samples were collected and analyzed from all participants. Fecal samples were sequenced using 16 S rDNA gene sequencing. Plasma metabolomics analysis was performed using liquid chromatography-tandem mass spectrometry. Results Compared to the non-obese normal group, non-obese PCOS showed significant increases in hirsutism scores, acne scores, LH, LH/FSH, testosterone, E2, and dehydroepiandrosterone（P＜0.05）. In comparison to the obese normal group, obese PCOS exhibited significantly higher hirsutism scores, LH/FSH, and testosterone, along with significantly lower FSH（P＜0.05）. Differential abundance analysis identified four genera（Finegoldia, Anaerococcus, Sneathia, and Adlercreutzia） significantly associated with obesity status（P＜0.05）. Finegoldia, Anaerococcus, Sneathia, and Adlercreutzia showed significantly lower abundance in obese females compared to non-obese females（P＜0.05）. Stratified analysis based on PCOS status revealed a significant negative correlation between Finegoldia and Anaerococcus with obesity in both PCOS and non-PCOS females. There were suggestive but not significant interactions between PCOS and obesity with Sneathia and Adlercreutzia(PPCOS×Obesity=0.090, 0.057). Anaerococcus exhibited a negative correlation with the ratio of indole-3-acetic acid to tryptophan and valine（r=-0.38,-0.30, P=0.007, 0.041）, while Adlercreutzia showed a negative correlation with proline and alanine（r=-0.37,-0.32, P=0.012, 0.034）. Conclusion In PCOS females, obesity is associated with changes in gut microbiota and plasma metabolites, including the depletion of bacteria producing butyrate and increased tryptophan degradation metabolism. These findings suggest potential interrelationships among gut microbiota, obesity, and PCOS. [ABSTRACT FROM AUTHOR]

ObjectiveThe aim is to investigate the effect of electrogenic microorganisms on the electricity generation and perforinances of sediment microbial fuel cell(SMFC) battery system using oily sludge as anode sludge by changing the types and distribution patterns of electricity-producing microorganisms. Methods The output voltage, power density and apparent internal resistance were collected. The oil removal rate was measured, and the electricity generation and degradation properties of SMFC and SMFC were compared, and the effects of different strains on the properties of SMFC were investigated. ResultsIn the single bacteria SMFC, Citrobacter Frei SMFC had better electricity generation and degradation performances than the other five single bacteria SMFC. The electricity generation and degradation performance of mixed bacteria-SMFC were significantly improved comparing with that of single bacteria-SMFC, and Bacillus cereus+Bacillus palpis intermediate-SMFC had the best electricity generation and degradation performance, and the output voltage could reach 515.30 mV. The distribution of the bacteria around the anode material and in the anode bottom mud could degrade the organic matter in the oily sludge, but the distribution of the bacteria in the anode material is more conducive to the performance of SMFC's electricity generation and degradation. Conclusion Mixed bacteria could significantly improve the electricity generation and degradation performance of SMFC when comparing with single bacteria, and the distribution of bacteria on the anode material is more beneficial to the electricity generation and degradation performance of SMFC. [ABSTRACT FROM AUTHOR]

Copyright of Acta Materiae Compositae Sinica is the property of Acta Materiea Compositae Sinica Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Bulletin of Soil & Water Conservation is the property of Bulletin of Soil & Water Conservation Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In order to optimize the implementation complexity and information transmission speed of the fifth generation communication technology, the Polar code based on channel polarization phenomenon gradually receives great attention and research, and forms many industry standards and research conclusions. In recent years, the development and optimization of Polar code encoding and decoding technology promotes the popularity of the fifth generation communication technology, and the rapid application of the new generation communication technology greatly promotes the further iteration of the underlying encoding and decoding technology. By reviewing the research history of Polar code encoding and decoding technology, the research status and context of Polar code encoding and decoding technology in the fifth generation communication are summarized. On this basis, the problems and requirements of current coding and decoding theory are analyzed and discussed in depth, and the research ideas and trends of the underlying coding and decoding theory in the future communication technology are proposed. [ABSTRACT FROM AUTHOR]

Copyright of Telecommunications Science is the property of Beijing Xintong Media Co., Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Frontiers of Computer Science & Technology is the property of Beijing Journal of Computer Engineering & Applications Journal Co Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chemical Engineering of Oil & Gas / Shi You Yu Tian Ran Qi Hua Gong is the property of PetroChina Southwest Oil & Gas Field Company and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Practical Pharmacy & Clinical Remedies is the property of Editorial Department of Practical Pharmacy & Clinical Remedies and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的 探讨基于案例教学(CBL)和以问题为导向的学习(PBL)的多学科诊疗(MDT)的教学方 法在重症医学临床教学中的应用。 方法 选取2022年3月至2023年9月在西安交通大学第一附属医院外科 重症医学科轮转实习的规培医师共计56人作为研究对象,将其分为试验组和对照组。试验组采取CBL 和 PBL的MDT教学模式,对照组实施传统的以教师为主体的带教模式。采用两独立样本t 检验比较试验组和对 照组病例汇报和理论考核得分,采用χ² 检验分析两组规培医师综合评价得分。结果 共纳入56人参与本次 研究,其中试验组27人,对照组29人,与对照组比较,基于CBL和PBL的MDT教学模式结束后,试验组学生 理论考核[(85.04±4.67)分 vs.(79.28±6.15)分,P <0.05]及病历汇报分析[(86.11±5.42)分 vs. (75.90± 7.79)分,P <0.05]均较高;与对照组比较,试验组学生的综合评价得分明显升高,差异有统计学意义(P < 0.05)。结论 采用基于CBL和PBL的MDT教学方法,可显著提高重症医学住培医师的教学效果,对提升教 学质量具有积极意义。 [ABSTRACT FROM AUTHOR]

Copyright of Oilfield Chemistry is the property of Sichuan University, Oilfield Chemistry Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Chinese Journal of Cancer Biotherapy is the property of Editorial Office of Chinese Journal of Cancer Biotherapy and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Journal of Data Acquisition & Processing / Shu Ju Cai Ji Yu Chu Li is the property of Editorial Department of Journal of Nanjing University of Aeronautics & Astronautics and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Modern Preventive Medicine is the property of Modern Preventive Medicine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)