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An inertial viscous iterative algorithm is constructed for the common elements of variational inequality problems and fixed point problems. Under appropriate assumptions, it is proved that the iterative sequence generated by the constructed algorithm strongly converges to the common elements of the solution set of pseudo-monotone variational inequalities and the common fixed point set of a finite family of semi-contractive mappings by using demi-closed at zero,projection operator and other analysis techniques. Numerical experiments illustrate the effectiveness of the algorithm. The study of this paper improves and extends some recent relative results.(在Hilbert空间中，针对变分不等式问题和不动点问题的公共元，构造了一种惯性黏性迭代算法。在适当条件下，采用映射半闭定义和投影算子技巧，证明了所构造算法产生的迭代序列强收敛于伪单调变分不等式解集和半压缩映射有限族公共不动点集的公共元。数值实验结果说明了该算法的有效性。所得结果改进和推广了已有文献的一些结果。)

抗滑移性能是摩擦型高强度螺栓受剪连接的重要力学性能之一。为研究抗滑移性能的影响因素，设计并完成了单个高强度螺栓抗滑移性能试验和高强度螺栓群抗滑移性能试验，连接试件均为双面剪切且表面进行了抛丸处理。基于试验结果，建立了准确、可靠的有限元验证模型，据此对高强度螺栓受剪连接进行了参数分析，主要研究参数包括：螺栓预紧次序、连接板件厚度、垂直于内力方向的螺栓间距与边距以及顺内力方向的螺栓间距与边距。分析结果表明：连接板件最危险截面的塑性区分布对摩擦型高强度螺栓的抗滑移性能有着显著影响，设计时应考虑孔周应力集中现象对抗滑移承载力的折减；不同的截面受力情况对应的孔周应力集中系数存在明显差异。通过计算分析给出了螺栓抗滑移承载力折减系数建议值。相关研究成果可为摩擦型高强度螺栓受剪连接的设计提供改进思路。

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Sarcopenia is a progressive and systemic skeletal muscle disease and an important extrapulmonary complication of chronic obstructive pulmonary disease （COPD）. Multiple studies have confirmed that COPD patients with sarcopenia have more severe airflow obstruction and emphysema, higher dyspnea index scores, reduced quality of life and exercise capacity， frequent acute exacerbations, and increased mortality. Although sarcopenia has been mentioned as a complication of COPD for many years, current clinical practice has received insufficient attention and insufficient intervention. The main reason is that its pathogenesis is unknown and drug treatment regimens are ineffective. As more and more research has been done on COPD combined with sarcopenia in recent years, this article reviews the current research progress to pay attention to further research and early intervention, including new mechanisms, diagnostic criteria, and drug treatment progress. [ABSTRACT FROM AUTHOR]

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Aldehyde dehydrogenase 2 (ALDH2) is one of important factors against from the damage under oxidative stress in human body. A high proportion of East Asians carry ALDH2 inactive mutation gene. There are many diseases closely related to ALDH2, such as cardiovascular diseases, neurodegenerative diseases and liver diseases. Recent studies also have found that ALDH2 is associated with ferroptosis. Therefore, ALDH2 has becoming a potential target for the treatment of the above related diseases. Several types of small molecule activators with potential value of clinical application have been reported. The research progress on the structure and function of ALDH2, the relationship with human diseases and its activators were summarized in this paper. [ABSTRACT FROM AUTHOR]

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The water and sediment situation of the Yellow River has changed dramatically in the new era, and the boundary conditions of the reservoir and river channel have also undergone major adjustments. The water and sediment regulation of the Xiaolangdi Reservoir needs to be further innovated and optimized to give full play to its benefits. On the basis of the analysis of the measured water and sediment series at Tongguan Station in the middle reaches of the Yellow River for a hundred years, the criteria for distinguishing the wet and dry years could be taken, of which the water amount was 30% higher and 30% lower than that of the average value. The analysis of the laws of sediment discharge of the Xiaolangdi Reservoir and sediment transport in the lower reaches shows that wet years have the advantages of strong scouring capacity and large sediment transport potential and dry years have the disadvantages of weak scouring capacity and small sediment transport potential. The optimized operation mode of water and sediment regulation of the Xiaolangdi Reservoir, which took into account the changes of the incoming water and sediment from the Yellow River was further proposed. The applicability of the optimized operation mode under the current water and sediment situation was analyzed by using the measured water and sediment series since 2000. The results show that the optimized operation mode can extend the sediment retention period of the reservoir for 8 years and reduce the siltation volume of the reservoir by 818 million m3 on the basis of not silting the downstream channel, also increase the average daily storage capacity of the reservoir by 399 million m3. [ABSTRACT FROM AUTHOR]

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