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Copyright of CT Theory & Applications is the property of Editorial Department of CT Theory & Applications and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In the recent years, as the center of energy metabolism, the role of hypothalamus in the development of obesity has been increasingly emphasiszed. Hypothalamic neural stem cells (htNSCs) which control adult neurogenesis play a crucial role in sensing the metabolic state of the body and maintaining energy balance by altering differentiation pathways, exosome functions, and mitigating inflammatory. By studying the hypothalamus and htNSCs, we can gain a better understanding of the mechanisms behind energy metabolism disorders in obesity and identify potential therapeutic targets for obesity and metabolic syndrome. [ABSTRACT FROM AUTHOR]

Copyright of Acta Geoscientica Sinica is the property of Acta Geoscientica Sinica Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Science Technology & Engineering is the property of Chinese Society of Technology Economics and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Computer Engineering & Applications is the property of Beijing Journal of Computer Engineering & Applications Journal Co Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Hydrogeology & Engineering Geology / Shuiwendizhi Gongchengdizhi is the property of Hydrogeology & Engineering Geology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Preventive Veterinary Medicine / Zhongguo Yufang Shouyi Xuebao is the property of Chinese Journal of Preventive Veterinary Medicine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Natural Disasters is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Experimental Technology & Management is the property of Experimental Technology & Management Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Geoscientica Sinica is the property of Acta Geoscientica Sinica Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Preventive Veterinary Medicine / Zhongguo Yufang Shouyi Xuebao is the property of Chinese Journal of Preventive Veterinary Medicine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Preventive Veterinary Medicine / Zhongguo Yufang Shouyi Xuebao is the property of Chinese Journal of Preventive Veterinary Medicine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This study explored the influence of design parameters on hydraulic performance and pollutants purification effect of free water surface flow constructed wetlands and selected the optimal design comprehensively considering the hydraulic and pollutants purification effects. An orthogonal test with multi-factor and multi-level of design parameters were performed to access their effects. The test site was located in the experimental base of the Jiangxi Province Center Station of Irrigation Experiment, in the Ganfu Plain of Poyang Lake basin. The geographical coordinates of the basin are 115°49′-116°46′E, 28°24′-29°46′N, characterized by a typical subtropical and humid monsoonal climate with an annual average temperature of 18.1 °C and an annual average rainfall of 1 685 mm. The orthogonal design, L16 (44×23), consisted of 4 4-level factors, namely aspect ratio, water depth, plant spacing and flow rate, and 3 2-level factors that are in- and outlet layout, plant species and blank. The hydraulic performance was analyzed by analyzing tracing data with rhodamine WT as the tracer. The hydraulic index used here were the short circuit indicator, the mixing indicator, the effective volume ratio, and the moment index. The pollutants purification effect of each test plot was obtained through multiple sampling tests of equal time intervals during the test. The detected pollutants were total nitrogen, total phosphorus, and total suspended solids. This test achieved a good purification effect on pollutants, the average concentration removal rate of total nitrogen, total phosphorus and total suspended solids was 40.0%, 58.3%, and 40.3%, respectively. The results showed that there was a significant correlation between aspect ratio and most hydraulic and treatment performance indicators. Water depth had a significant effect on total nitrogen removal rate, and plant spacing had a significant impact on total suspended solids removal rate (P<0.1). The correlation analysis between evaluation index showed that there was a universally strong significant correlation among the hydraulic performance indicators and also a significant correlation among the pollutants purification effect index. The better the hydraulic performance would have the higher pollutants purification effect. According to range results, aspect ratio, water depth, and plant spacing were the main design parameters that affected the hydraulic and pollutants purification effect of free water surface flow constructed wetlands. The results of variance showed that the design parameters had a significant effect on the pollutants purification effect, but the influence on the hydraulic performance was not as significant. For the evaluation of hydraulic performance, the optimal combination of design parameters consisted of an aspect ratio of 8:1, a water depth of 30 cm, a plant spacing of 30 cm, a flow rate of 0.55 m3/h, a layout of central pass in- and outlet, and Typha latifolia as the plant species. For the evaluation of pollutants purification effect, the optimal combination of design parameters consisted of an aspect ratio of 4:1, a depth of 30 cm, a plant spacing of 20 cm, a flow rate of 0.55 m3/h, a layout of central pass in- and outlet, and Scripus tabernaemontani as the plant species. Combining the results of the hydraulic and pollutants purification effect, the design parameter combination composed of an aspect ratio of 4:1, a depth of 30 cm, a plant spacing of 20 cm, a flow rate of 0.55 m3/h, a layout of central pass in- and outlet, and Scripus tabernaemontani as the plant species, resulted in an optimal overall performance. Since an excellent purification capacity was the ultimate goal for wetland design, the optimal design parameter combination for overall performance was the same as that for pollutants purification effect in this study. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Preventive Veterinary Medicine / Zhongguo Yufang Shouyi Xuebao is the property of Chinese Journal of Preventive Veterinary Medicine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objectives: Toxicity from radiation therapy is a reflection of the quality of treatment, and will influence the quality of life of patients. The aim of this study was to investigate the effects of demographic, disease and radiotherapy factors on the toxicity of radiation therapy for patients with head and neck cancer. Methods: This was a retrospective study with secondary data analysis. A total of 606 head and neck cancer patients were enrolled in this study from January 1, 2013 to December 31, 2015 in a regional hospital in Southern Taiwan. This study was approved by the institutional review board of E-DA hospital. Descriptive statistics and logistic regression analysis were used to analyze the factors associated with radiation therapy toxicity of the mouth and skin. Results: The results of multivariate logistic regression analysis showed that treatment fraction and immobilization techniques had a significant influence on the side effects on the skin to a mild or severe degree, age and body weight index had a significant influence on the side effects on the mouth to a mild degree, and tumor site had a significant influence on the side effects on the mouth to a mild or severe degree. Conclusions: Immobilization technique is a controllable factor in that changing the selection of immobilization technique can reduce the effects on the skin. This may provide valuable information for radiology physicians when they design a patient’s treatment plan. The results may also help medical care staff understand radiation side effects, provide immediate medical services, and improve the quality of radiation therapy. [ABSTRACT FROM AUTHOR]

Objectives: A clinical manifestation of rheumatic disease is chronic inflammation that may increase the risk of cancer. The purpose of this study was to explore the risk of cancer and the precancerous medical utilization by children with rheumatism in Taiwan. Methods: This was a retrospective study with secondary data analysis. The data were drawn from the National Health Insurance Research Database from 2000 to 2012. Patients under the age of 18 with a diagnosis of pediatric rheumatic disease, including systemic lupus erythematosus, juvenile idiopathic arthritis, Sjögren’s syndrome, scleroderma, polymyositis, dermatomyositis, vasculitis and Behçet’s disease. A total of 1,741 cases were identified. The Cox proportional hazards model was used to analyze the risk of cancer, and the Mann-Whitney U Test was used to assess whether the patient’s medical use was different from that in the year prior to the diagnosis of cancer. Results: The overall risk for children with rheumatism compared with non-rheumatic patients was 3.71 times the risk for cancer; for systemic lupus erythematosus, juvenile idiopathic arthritis and Sjögren’s syndrome, the cancer risk was 3.94 times, 5.93 times and 5.29 times, respectively. The risk for cancer was increased by 5.65 times in those who had used immunoregulatory drugs, and this was 26.01 times more than that of those who had used biological agents. For children with rheumatism, in the year before the diagnosis of cancer and in terms of overall medical use before cancer, the number of outpatient visits and expenses increased, but the number of hospitalizations, hospital days, and cost reduction were not significantly different. Conclusions: Based on the results of this study, we suggest that the health authorities pay more attention to the medical care of children with rheumatism in order to avoid future social costs. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the clinical efficacy and therapeutic progress of orthotopic liver transplantation for the treatment of hepatic epithelioid hemangioendothelioma （EHE）. Methods Clinical data of 2 patients diagnosed with hepatic EHE were retrospectively analyzed. One patient（case 1） was diagnosed with multiple hepatic EHE complicated with multiple infarction lesions of the spleen, and underwent orthotopic liver transplantation combined with splenectomy. The other case（case 2） was diagnosed with multiple hepatic EHE and received orthotopic liver transplantation alone. Literature review was performed. Pathological characteristics, clinical efficacy of liver transplantation and clinical prognosis of hepatic EHE patients were analyzed. Results Two patients successfully underwent surgery and were discharged postoperatively. The diagnosis of hepatic EHE was confirmed by pathological examination and case 1 was complicated with EHE of the spleen. For case 1, tacrolimus was replaced by sirolimus at postoperative 1 month. At postoperative 4 months, capecitabine was orally administered （chemotherapy） for EHE recurrence. At 6 months after surgery, the patient was diagnosed with recurrent hepatic EHE complicated with multiple bone metastases, and was orally administered with sorafenib. At postoperative 7 months, the patient died from cachexia and liver failure. Case 2 was followed up until the submission date （8 months after surgery）. No postoperative complications and tumor recurrence were observed. Previous studies had demonstrated that surgical resection was the primary therapy of hepatic EHE. Liver transplantation was highly recommended for patients with multiple unresectable hepatic EHE and extra-hepatic lesions. Moreover, chemotherapy, percutaneous puncture combined with transcatheter arterial chemoembolization and anti-angiogenesis treatment exerted certain clinical efficacy. Conclusions Surgical resection remains the primary therapy of hepatic EHE. For patients with multiple intrahepatic EHE, liver transplantation is considered as the optimal treatment. Much attention should be diverted to the prevention and treatment of recurrent hepatic EHE following liver transplantation, aiming to improve the clinical efficacy. [ABSTRACT FROM AUTHOR]