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Objective To analyze the mediating effect of depressive symptoms between unhealthy lifestyle and body mass index (BMI), and to provide a reference basis for the prevention of common diseases among adolescents. Methods In 2023, 88, 594 students were selected by random stratified, class - based cluster sampling method from 12 municipalities in Inner Mongolia (103 counties) for questionnaire survey, to describe the basic demographic characteristics of the students, to explore the correlation between unhealthy lifestyle, depressive symptoms and BMI, and to establish the mediation effect model by using the PROCESS macro program in SPSS 26. 0. Results The number of detections of unhealthy lifestyle was 85 866, with a detection rate of 96. 92 percent; the number of detections of abnormal BMI was 32 078, with a detection rate of 36. 21 per cent; and the number of detections of depressive symptoms was 19, 356, with a detection rate of 21. 85 per cent. The results showed that the mediating effect value of depressive symptoms on unhealthy lifestyle and body mass index was 0. 0770, 95% CI: 0. 0513 - 0. 1027, and the mediating effect accounted for 11.35% of the total effect, which indicated that unhealthy lifestyle could mediate the increase of BMI through depressive symptoms. Conclusion Adolescents can prevent abnormal body mass index by improving unhealthy lifestyles, and they can also improve the occurrence of depressive symptoms and thus maintain a normal body mass index. [ABSTRACT FROM AUTHOR]

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