Search

Copyright of Chinese Journal of Aesthetic & Plastic Surgery is the property of Chinese Journal of Aesthetic & Plastic Surgery Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Laboratory Medicine is the property of Journal of Modern Laboratory Medicine Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Laboratory Medicine is the property of Journal of Modern Laboratory Medicine Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Aesthetic & Plastic Surgery is the property of Chinese Journal of Aesthetic & Plastic Surgery Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To explore the expressions of Runx2 and osteopontin (OPN) in human breast cancer tissue and their association with the formation of microcalcification. Methods The expressions of Runx2 and OPN were detected in breast cancer tissue of 62 cases by immunohistochemical method. Then the 62 cases were divided into three groups: non-microcalcification, mild-microcalcification and high-microcalcification groups according to the amount of microcalcification shown on mammography in breast cancer. The association of Runx2 and OPN expressions with microcalcification was further studied. Results The positive expression rate of Runx2 and OPN in human breast cancer tissue was 72.6% and 79.0%, respectively. The positive expression of Runx2 and OPN proteins was significantly correlated with the amount of microcalcification, but not with the morphology of microcalcification in breast cancer tissue. The positive rate of Runx2 and OPN was gradually elevated with the increase in the amount of microcalcification (x2=15.686, P<0.05; x2=16.161, P<0.05), respectively. Conclusion Runx2 and OPN proteins are highly expressed in human breast cancer tissue and they may participate in the process of microcalcification formation in breast cancer. [ABSTRACT FROM AUTHOR]