1. 新型低蛋白肠内营养制剂对慢性肾脏疾病患者 效果研究.
- Author
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郭鉴葵, 周子琪, 柳园, 陈懿, 黄月阳, and 胡雯
- Abstract
Objective To explore the effect of a new type of low-protein enteral nutrition on the nutritional status of patients with chronic kidney disease in stage 3-4 under the guidance of individualized diet. Methods Sixty follow-up outpatients in West China Hospital of Sichuan University were randomly divided into the experimental group and the control group. The two groups were followed up on intervention day 0, day 45, and day 90. According to the principle of intentional analysis, the generalized estimation equation was used to analyze the between-group differences, time change trend, and interaction effect, and the principle of data analysis in accordance with the scheme was used to further verify the stability of results. Results There was no significant difference in nutritional adequacy, clinical effectiveness, and anthropometric indexes between the test group and the control group (P > 0.05). During the intervention period, when the energy intake was stable, the intake of protein (於=17.680, P<0,001) and sodium salt (=21.427, P<0»001) decreased significantly, while the total protein (於=18,075, P<0.001), calcium (护=9.43& P=0,009), phosphorus (护=13.866; P=0.001), and uric acid (於=9,005, P=0.011) fluctuated within the normal range. The results of data analysis in accordance with the scheme were basically consistent with those of intentionality analysis. Only the time change trend of upper arm muscle circumference (於=6.435: P=0.040) and the comparison of energy ratio between groups (於=4.47& P=0.034) were significantly different. Conclusion The new low-protein enteral nutrition preparation is not inferior to the total nutritional formula food for special medical use in improving the nutritional status of patients and delaying the progression of the disease. The use of enteral nutrition under dietary guidance is beneficial to the clinical nutrition management of patients with chronic kidney disease. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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