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Copyright of China Journal of Oral & Maxillofacial Surgery is the property of Shanghai Jiao Tong University, College of Stomatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Aesthetic & Plastic Surgery is the property of Chinese Journal of Aesthetic & Plastic Surgery Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective By knocking down the expression of N6-methyladenine (m6A) methyltransferase Wilms' tumor 1-associated protein (WTAP) in cutaneous squamous-cell carcinoma (cSCC) cells, the effects of WTAP on the proliferation, migration, and invasion of cSCC cells were investigated. Methods Human cSCC cells A431 and SCL-1 and normal human epidermal keratinocytes HaCaT were selected. Western blotting and qRT-PCR were used to detect the protein and mRNA expression levels of WTAP in each cell. A431 cells with the highest expression of WTAP protein and mRNA were transfected with WTAP knockdown lentivirus shWTAP-1, shWTAP-2, shWTAP-3 and negative control lentivirus shNC, and the transfection efficiency was verified by qRT-PCR and Western blotting. The shWTAP-3 transfected cells with the most significant knockdown difference were selected as the WTAP knockdown group, and the shNC transfected cells were selected as the control group. The expression of m6A was detected by colorimetric assay, the proliferation ability of cells was detected by CCK-8 assay and colony formation assay, the invasion ability of cells was detected by Transwell assay, and the migration ability of cells was detected by cell scratch assay. Results The expression of m6A in the WTAP knockdown group was lower than that in the control group, OD value at each time point was lower than that in the control group, the number of colony formation was smaller than that in the control group, and the number of transmembrane cells and cell migration rate were lower than those in the control group (all P<0. 05), Conclusions Knocking down WTAP can inhibit the proliferation, invasion and migration of cSCC cells, which may be achieved by down-regulating the expression of m6A. [ABSTRACT FROM AUTHOR]

Copyright of China Journal of Oral & Maxillofacial Surgery is the property of Shanghai Jiao Tong University, College of Stomatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

胸骨正中切口的应用，促进了心脏外科手术的发展，为心血管疾病患者带来了福音。近年来，随着该类手术的增 加，术后深部胸骨切口感染患者数量逐年增多，处理较为棘手，其并发症严重影响患者的预后。现对深部胸骨伤口感染的分型、 相关影响因素、诊断及治疗进行回顾与分析，以期为这类患者的治疗提供临床参考。 [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Aesthetic & Plastic Surgery is the property of Chinese Journal of Aesthetic & Plastic Surgery Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Aesthetic & Plastic Surgery is the property of Chinese Journal of Aesthetic & Plastic Surgery Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Journal of Oral & Maxillofacial Surgery is the property of Shanghai Jiao Tong University, College of Stomatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To explore the value of territorial arterial spin labeling(t-ASL) in perioperative period of carotid endarterectomy(CEA). Methods 30 patients scheduled CEA due to carotid stenosis underwent t-ASL 2 weeks before and 1 week after surgery to generate cerebral blood flow(CBF) images and brain blood supply area maps respectively. The CBF values of bilateral internal carotid artery(ICA) territory and the perfusion volume(PV) of bilateral ICA and vertebral basilar artery(VBA) territory were measured. And then, the total perfusion volume(PVT) was calculated. The paired-sample t-test was used to compare the CBF value and the PV difference before and after surgery respectively. The independent sample t-test was used to compare the PVT difference between the hyperperfusion group and the non-hyperperfusion group. Results （1）The CBF value of the affected side was lower than that of the contralateral side preoperatively. The CBF values of both the affected side and contralateral side increased after CEA, and the increase of affected side was greater than that of contralateral side. （2）Before CEA, PV on affected side was lower than that on contralateral side. After CEA, PV on affected side was significantly increased, while PV on contralateral side and the VBA territory decreased. （3） PVT in the hyperperfusion group were significantly lower than that in the non-hyperperfusion group before CEA and there was no significant difference between two groups after CEA. Conclusion As a non-invasive cerebral perfusion imaging method, t-ASL can not only be used to predict the surgical outcome and the risk of hyperperfusion syndrome accident before CEA, but also be used for postoperative evaluation of surgical treatment. [ABSTRACT FROM AUTHOR]