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目的既往有研究表明，输注较长时间储存的红细胞可能使疾病的预后变差，尤其是创伤、重症和接受心脏手术的病人。为了探讨在肿瘤病人当中，输注红细胞的储存时间对肿瘤病人的远期预后是否有影响，本回顾性研究分析了术中输注红细胞对肝细胞癌切除术后病人的复发及总生存率的影响。方法本研究收集了2008年8月1日至2012年6月30日于中山大学肿瘤防治中心（中国，广州）接受肝细胞癌切除术的病人1221例，分为输血组与未输血组，其中输血组根据输注红细胞的储存时间进一步分为新鲜红细胞组（储存时间≤14 d）和陈旧红细胞组（储存时间＞14 d）。对患者的总生存时间，肝内无复发生存时间，肝外无转移生存时间进行了分析，并采用多因素分析对不同储存时间的红细胞与肿瘤预后进行相关性分析。结果术中输注红细胞的病人共251例（20.6%），除14例患者新旧红细胞均有输注外，新鲜红细胞组112例，陈旧红细胞组125例。Kaplan–Meier生存分析显示输血组的总生存时间，肝内无复发生存时间，肝外无转移生存时间都更差（P=1.417， P=0.049）和肝内无复发生存时间（HR=1.519， P=0.013）的独立影响因素，新鲜红细胞却不是。结论在接受肝细胞癌切除术的病人中，术中输注储存时间超过14 d的库存红细胞会增加术后肝内复发的风险且会缩短总生存时间，是一个影响预后的独立危险因素。

目的分析食管鳞癌患者（ESCC组）与健康对照组（HC组）肿瘤组织菌群多样性，筛选出食管鳞癌患者肿瘤组织中特异性细菌。方法收集105例食管鳞癌患者肿瘤组织标本和54例健康对照者的食管组织标本，提取标本总DNA，用PCR方法扩增16S rDNA V4区，后行高通量测序，将数据做OTU聚类及多样性分析筛选食管鳞癌组织内特征菌。最后用定量PCR（Q-PCR）扩增方法验证筛选结果。结果多样性分析表明ESCC组肿瘤标本和HC组正常食管组织标本内菌群多样性及组成存在明显差异，物种分析表明ESCC组以梭杆菌属（Fusobacterium）、孪生球菌属（Gemella）、奈瑟菌属（Neisseria）、卟啉单胞菌属（Porphyromonas）、链球菌属（Streptococcus）为主，HC组以梭杆菌属（Fusobacterium）、放线杆菌属（Actinobacillus）、链球菌属（Streptococcus）、普雷沃氏菌属（Prevotella）为主，LEfSe分析表明ESCC组卟啉菌属、梭杆菌属丰度升高，且具有统计学差异（P

路由协议是自动交换光网络（ASON）控制平面的重要组成部分,其负责泛洪网络的链路状态信息,并进行路由计算。在ASON的实际运行过程中,路由协议存在一些不足,如占用大量数据通信网（DCN）带宽以及链路状态数据库同步时延过大等,这些问题对网络的可扩展性有较大影响。文章针对上述问题提出了路由协议的优化方案,包括为路由信息的泛洪设定阈值,以及给路由协议增加数据库自更新功能。

Copyright of Chinese Journal of Computational Mechanics / Jisuan Lixue Xuebao is the property of Chinese Journal of Computational Mechanics Editorial Office, Dalian University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Currently, there are fewer microphone position estimation methods and only position estimates are made for a planar microphone array. Aiming at this problem, this paper proposed a spatial microphone positioning method based on sound source array. The method arranged four sound sources in the form of a regular tetrahedron. While using its symmetry to ensure the omnidirectionality of the positioning, the distance between the microphone and each sound source was calculated according to the ranging method of the time delay estimation. The microphone position coordinates were then determined based on the geometric relationship to realize the spatial microphone position estimation based on the sound source array for online positioning. The experimental results verify the feas ibility and effectiveness of the proposed method by MATLAB simulation experiment. [ABSTRACT FROM AUTHOR]

Farmer and soil surveys were conducted to explore the nitrogen balance and greenhouse gas emission reduction potential in typical Oolong tea gardens. Based on the Boundary line approach，survey data from 355 farmers and 207 soil tests in tea gardens of Anxi Coun⁃ ty and Wuyishan City in Fujian Province from 2015 to 2017 were collected to analyze the characteristics of nitrogen fertilizer application， nitrogen balance，and greenhouse gas emission reduction potential. The results showed that the average amount of nitrogen fertilizer input in Anxi County tea gardens was 509.4 kg·hm-2，mainly from compound fertilizer and urea，and the annual nitrogen surplus was 479.1 kg· hm-2. The average amount of nitrogen fertilizer input in tea gardens in Wuyishan City was 218.1 kg·hm-2，mostly from compound fertilizer， and the annual nitrogen surplus was 189.8 kg·hm-2. There was a significant positive correlation between nitrogen input and nitrogen nutri⁃ ent surplus. With the increase of nitrogen surplus，soil total nitrogen content also increased，and the total nitrogen content of tea gardens in Anxi County was higher than that in Wuyishan City. Based on the Boundary line method，the optimal nitrogen fertilizer application rate in tea gardens of Anxi County and Wuyishan City was 411.3 kg·hm-2 and 157.7 kg·hm-2，respectively. The greenhouse gas emission could be reduced by 62.0% and 68.0% respectively by optimizing the input and management level of nitrogen fertilizer. This study demonstrated that excessive application of nitrogen fertilizer leaded to high surplus of nitrogen in the Oolong tea gardens of Anxi County and Wuyishan City in Fujian Province. The amount of nitrogen fertilizer should be optimized to reduce excessive surplus of nitrogen and reduce greenhouse gas emissions from tea garden. [ABSTRACT FROM AUTHOR]

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Copyright of Theoretical Studies of Literature & Art / Wenyi Lilun Yanjiu is the property of Editorial Board of Theoretical Studies in Literature & Art and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Traditional antenna optimization designs need numerous simulation trials of different parameter combinations to reach the optimum, which leads to low efficiency in solving high dimensional antenna design and optimization problems. To address this issue, we design an initial Kriging model by using a few uniformly distributed sampling points and their simulation data. During the optimization iterations, the population of each generation is comprised of individuals with high fitness as well as individuals with high diversity. The optimal individual is selected according to its responses and uncertainty predicted by the Kriging model. Electromagnetic simulations are conducted for this individual, and the results are used to update the Kriging model. This algorithm is applied to optimize the resonant frequencies of an E-shaped antenna with 6variables. Compared with other optimization methods, the number of EM simulation is reduced by about 80%. [ABSTRACT FROM AUTHOR]

泥石流的形成，必须同时具备丰富的松散堆积物、足够的水源和有利的地形地貌3个基本条件.控制调节水动力条件是防止泥石流灾害发生的有效方法，而采用具有自清淤能力的水石分离虹吸排水技术，将分流进入泥石流沟内的水直接排入下游安全区，从而达到减小泥石流沟谷的水动力、防止泥石流启动的目的.而保证泥石流治理效率和耐久性的前提是分流池的自清淤能力.应用计算流体力学软件CFD建立三维数值模型，采用欧拉动床模型对分流池在虹吸作用下的水力特性进行分析，并用物理模型模拟验证了虹吸排水清淤的可行性.分析结果表明：床面不平整有利于泥沙起动悬浮；进出口水头差、泥沙粒径及淤积厚度、泥沙之间的碰撞都会对虹吸清淤效率产生影响.所得结论对实际泥石流防治工程中虹吸分流池的设计，如负压水头、拦污格栅孔径的选取具有一定的指导意义.