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Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Railway Standard Design is the property of Railway Standard Design Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Tropical Medicine is the property of China Tropical Medicine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

OBJECTIVE: To probe into the effects of sufentanil combined with ropivacaine in epidural anesthesia on immunologic (unction and stress indices in patient undergoing caesarean section. METHODS: 80 patients undergoing caesarean section admitted into Banan People’s Hospital of Chongqing from Jan. 2017 to May 2018 were selected and divided into observation group and control group via random number table, with 40 cases in each group. The control group was given 0.75% of ropivacaine for anesthesia, while the observation group was given sufentanil combined with 0.75% of ropivacaine. The anesthetic effects, immune indices levels, incidences of intraoperative complications, incidences of neonatal asphyxia and Apgar score of both groups were observed. The heart rate (HR), mean arterial pressure (MAP), cortisol (Cor) and norepinephrine (NE) levels at before anesthesia (T0), 10 min after administration (T1), skin incision (T2), fetus removal (T3) and extubation (T4). RESULTS: The anesthetic onset lime and duration of analgesia of observation group were significantly better than those of the control group, with statistically significant difference (P<0.05) ; there was no statistical significance in difference in the muscle relaxation scores between two groups (P> 0.05). At T2, T2, T3 and T4, the MAP and HR levels of observation group were significantly lower than those of the control group, with statistically significant differences (P<0.05) ; while there were no statistical significance in differences in MAP and HR levels among different lime points in observation group (P>0.05). At T2, T3 and T4,the serum Cor and NE levels of both groups were significantly higher than that of 70, while the serum Cor and NE levels of observation group were significantly lower than those of the control group (P<0.05). At the end of operation and 3 days alter operation, the GD3+, CD4+ and CD4+/CD8+ levels in peripheral blood of both groups were significantly lower than those of before operation, while those of the observation group were significantly higher than the control group, with statistically significant differences (P<0.05). The incidences of intraoperative complications of observation group and control group were respectively 5.00% (2/40) and 10.00% (4/40), the difference had no statistical significance (P> 0.05). There were no statistical significance in differences in the incidences of neonatal asphyxia, Apgar scores at lmin and 5 min between the two groups (P>0.05). CONCLUSIONS: Sufentanil can improve the anesthetic effect of ropivacaine for epidural anesthesia in patients undergoing caesarean section, weaken the hemodynamic fluctuation during operation, reduce stress response and improve postoperative immunologic function. [ABSTRACT FROM AUTHOR]

Copyright of China Tropical Medicine is the property of China Tropical Medicine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Transient Receptor Potential channels are important intracellular Ca2＋ regulators, which are characterized by unique distributions and interactions with other calcium sensing elements within cells. TRP channels regulates a plethora of cellular physiological activities, such as autophagy and apoptosis through its regulation on calcium. Those channels located on cytoplasmic or organelles membrane can increase intracellular Calcium concentration [Ca2＋]i, which can be used for the initiation of autophagy. The priority of autophagy is to enable the cells to survive under stress conditions, such as hypoxia, nutrient deprivation and pathological factors, by recycling certain cellular components for the needs of important physiological activities, but lots of studies have shown that excessive autophagy leads to apoptosis-related-programmed cell death. So the role of TRP pathway in the regulation of antophagy may be closely related to the occurrence and development of diseases, for example, TRPML1 （Transient Receptor Potential mucolipin-1） is associated with type IV mucosal lipidosis. Based on all the research results of TRP channels and autophagy, different TRP channels can increase cytoplasmic calcium through different mechanisms. TRPV channels are mainly located on cytoplasmic membrane or endoplasmic reticulum membrane, but TRPML functions mainly on lysosome. It is probably because of their specific intracellular localization, while its molecular mechanisms needs further study. [ABSTRACT FROM AUTHOR]