Objective To investigate the satisfaction of inpatients with telemedicine services, further improve their medical experience, and promote the quality of telemedicine services in Xinjiang region. Methods A total of 1 446 inpatients were randomly selected from 92 public hospitals in 14 prefectures and autonomous prefectures of Xinjiang. A self-designed electronic questionnaire was used to conduct a satisfaction survey among patients who received telemedicine services. Results The overall satisfaction rate of inpatients receiving telemedicine services in Xinjiang region was relatively high (94.16%), and the audience tended to be younger (patients under 50 years old accounted for 79.19%). The main reason for 72. 68% of patients choosing telemedicine services was to reduce medical costs, rather than the level of expertise provided by remote service specialists. After receiving telemedicine services, 93.50% of patients had increased confidence in subsequent treatments, and 85. 96% of patients believed that the treatment effect had been significantly improved. Conclusion Currently, the satisfaction with telemedicine services among inpatients in Xinjiang region is relatively high, but there exists a mismatch between telemedicine service capabilities and patient satisfaction. Therefore, it is necessary to expand the scope of telemedicine services, strengthen science popularization and promotion, and enhance patients′ experience with diagnosis and treatment. [ABSTRACT FROM AUTHOR]