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Objective To analyze the risk factors for IgA nephropathy complicated with hyperuricemia in renal function compensatory phase of patients in western part of Guangdong province. Methods The clinical and pathological data of 328 patients with IgA nephropathy were selected to analyze the risk factors of hyperuricemia. Results The incident of hyperuricemia in patients with IgA nephropathy was 38.4% ( (26/328). Univariate regression analysis suggested that the age, serum creatinine , blood urea nitrogen , serum triglyceride , serum total cholesterol , glomerulus sclerosis score , glomerular injury integral, tubular-interstitial injury score, renal small vessel injury score and Lees grade might be related to the IgA nephropathy patients complicated with hyperuricemia (all P <0.05). Multivariate regression analysis showed that the serum triglyceride and renal small vessel injury score > 2 were related with the occurrence of hyperuricemia in patients with IgA nephropathy (all P <0. 05). Conclusion The hypertriglyceridemia and renal small vessel injury score >2 are independent risk factors for patients with IgA nephropathy in renal function compensatory phase from western part of Guangdong province. [ABSTRACT FROM AUTHOR]