1. 胸椎QCT诊断骨质疏松BMD阈值的临床研究.
- Author
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刘斋, 赵君禄, 赵保根, and 任庆云
- Abstract
Objective To analyze the correlation between thoracic and lumbar bone mineral density and to identify specific diagnostic thresholds of osteoporosis and osteopenia for the thoracic spine. Methods Retrospective analysis of 276 patients who received abdomen non-contrast-enhanced CT scan for otherindication. BMD of each vertebra spanning T10–L3 was measured, the correlation between BMD of each vertebral body, mean T10-T12 BMD and mean L1-L3 BMD were analyzed using Pearson analysis. The cut-off values of thoracic spine (T10-12) averaged BMD for osteoporosis and osteopenia were calculated using linear regression. Results The BMD of vertebral body from T10 to L3 gradually decreased, with the highest BMD in the T10(120.49 ± 35.96 mg/cm3) and lowest at L3 (95.62 ± 35.95 mg/cm3). Significant correlations in BMD among all measured thoracic and lumbar levels were observed(r=0.894-0.967, P<0.05), and a Pearson’s correlation coefficient between mean T10-T12 BMD and mean L1-L3 BMD was 0.957. Respective cut-off values of mean T10-T12 BMD for osteoporosis and osteopenia was 96.59 mg/cm3 and 134.75 mg/cm3. Conclusion There is a high correlation between mean L1-L3 BMD and mean T10-T12 BMD, BMD measurement of thoracic spine can be used as a method for diagnosis of osteoporosis and osteopenia. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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