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Objective To explore the status quo of ICU nurses' knowledge, attitude and practice of physical restraints use in general hospitals in Guangxi, and to provide a theoretical basis for clinical training and quality control. Methods A simple random sampling method was used to select ICU nurses from Grade III and Grade II hospitals in Guangxi, including 2 Grade III hospitals and 3 Grade II hospitals, with a total of 201 ICU nurses. The knowledge, attitude and practice status of nurses on physical restraints use were investigated by using a physical restraints knowledge, attitude and behavior questionnaire, and the influencing factors were analyzed. Results The total score and scores of knowledge dimension, attitude dimension, and behavior dimension were (135. 08±18. 07), (68. 70±9. 49), (20. 73±4. 82), (45. 66±8. 95), respectively, indicating a low-to-medium level awareness of physical restraints among ICU nurses in general hospitals in Guangxi. There were statistically significant differences in the level of knowledge, attitude and practice of ICU nurses with different hospital levels, ICU working years, and ICU specialist qualifications (P＜0. 05). Conclusion ICU nurses in Guangxi have a more positive attitude towards physical restraint, and their knowledge and behavior level need to be strengthened urgently. ICU managers should improve the physical restraint training mechanism, types and teams of ICU nurses, strengthen relevant knowledge and skills training according to the different characteristics of nurses, build positive attitudes and emotions through enhanced knowledge, promote behavioral changes, and improve the development of physical restraint specialization. (目的 探讨广西壮族自治区ICU护士身体约束知信行现状, 为临床开展相关的培训及质控提供理论依据。方法 采用简单随机抽样法, 选取广西壮族自治区三级甲等、二级甲等共5所医院的ICU护士共201名作为研究对象, 采用“ICU护士实施身体约束知信行评估量表”调查护士对患者实施身体约束的知识、态度和行为现状, 并分析影响因素。结果 广西壮族自治区ICU护士身体约束知信行总分、知识维度、态度维度、行为维度得分分别为(135. 08±18. 07)分、(68. 70±4. 82)分、(45. 66±8. 95)分, 整体上为中等偏低水平。不同医院等级、ICU工作年限、有无ICU专科资质的ICU护士身体约束知信行水平差异有统计学意义(P＜0. 05)。结论 广西壮族自治区ICU护士身体约束态度较为积极, 知识及行为水平亟待加强。ICU管理者应健全ICU护士身体约束培训机制、种类和队伍, 根据护士的不同特征强化相关知识与技能培训, 通过增强知识建立积极态度和情感, 促使行为改变, 促进身体约束专科化发展。)

Objective : To explore the clinical effect of moxibustion combined with microecological preparations in the treatment of diarrhea-predominant irritable bowel syndrome (IBS-D) based on hypothalamic-pituitary-adrenal axis. Methods : 142 liver depression and spleen deficiency syndrome IBS-D patients admitted to our hospital from March 2022 to July 2023 were divided into control group (treated with microecological preparations, n=71) and study group (treated with moxibustion combined with microecological preparations, n=71) by using a random number table method. The chinese medicine syndrome scores, intestinal microecology, serum intestinal mucosal barrier function indexes [ D-lactic acid,diamine oxidase [ adrenocorticotropic hormone (ACTH), corticosterone (CORT), adrenocorticotropic hormone releasing hormone (CRH) ] were compared in two groups. Results : After treatment, the scores and total scores of abdominal pain was diarrhea, anxious and irritable, anorexia, two flank bilge full, tired and weak of the study group were lower than those of the control group at the same time (P＜0. 05). After treatment, fecal bifidobacterium, lactobacillus and bacteroides in the study group were higher than those in the control group at the same time. Enterobacter faecal bacteria and enterococcus in the study group were lower than those in the control group at the same time point (P＜0. 05). After treatment, serum D-lactic acid, DAO and endotoxin in the study group were lower than those in the control group at the same time point (P＜0. 05). After treatment, serum CORT, ACTH and CRH in the study group were lower than those in the control group at the same time (P＜0. 05). Conclusion : Moxibustion combined with microecological preparations in the treatment of IBS-D can effectively improve the clinical symptoms of patients, intestinal microecology and intestinal mucosal barrier function. It is speculated that the mechanism of action may be related to the regulation of the hypothalamic-pituitary-adrenal axis. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Inorganic Analytical Chemistry / Zhongguo Wuji Fenxi Huaxue is the property of Beijing Research Institute of Mining & Metallurgy Technology Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Aiming at the intelligent design of combat systems, we propose a conceptual framework and application methods of Agent based on artificial intelligence technology. First, we analyze the concept of Agent and discuss the important signifi- cance of studying Agent in the combat system. Then, we introduce the research framework of artificial intelligence based on Agent, and multiple application methods of Agent in combat systems. Finally, we analyze the development trends of Agent technology and the risks and challenges that its combat applications may face. [ABSTRACT FROM AUTHOR]

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Acute kidney injury (AKI) is a common and serious kidney disease with rising incidence and mortality rates. Disruption of fatty acid oxidation (FAO) is a significant pathological feature in the progression of AKI. Under AKI conditions, renal tubular epithelial cells (RTECs) undergo marked energy metabolic reprogramming, with particularly notable disturbances in fatty acid metabolism. Therefore, exploring the mechanisms associated with impaired fatty acid metabolism is crucial for developing effective therapies for AKI. This review comprehensively discusses the alterations in lipid metabolism in AKI, including fatty substances and metabolic enzymes related to FAO. It summarizes the adverse reactions caused by FAO metabolic reprogramming, such as autophagy, apoptosis, inflammation, and oxidative stress in cells. The review proposes that supplementing FAO-related metabolic products or inhibiting FAOrelated regulatory enzymes can effectively reverse abnormal metabolic processes in the kidneys, thereby reducing inflammation and oxidative stress, leading to effective treatment of AKI. This work provides insights that may facilitate further clinical research on AKI. [ABSTRACT FROM AUTHOR]

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成纤维细胞生长因子23 (FGF23) 是钙磷代谢的重要调节因子, 主要由骨细胞和成骨细胞分泌。FGF23 在甲状旁腺轴中起重要作用, 参与调控骨矿物质代谢, 通过作用于肾组织中的受体复合物Klotho调节钙磷代谢, 参与 终末期肾病患者矿物代谢和肾性骨病, 也与血管钙化, 心血管事件等有关, FGF23还与促红细胞生成素、铁代谢、炎 症存在双向作用, 这使得FGF23在肾性贫血, 感染等方面中也发挥重要作用, 有望成为治疗新靶点。 [ABSTRACT FROM AUTHOR]

[Objective Investigating the interactive coupling characteristics of the PEE system can provide theoretical support and quantitative basis for the ecological advancement of urban areas in the Three Gorges Reservoir Area. [Methods] Based on a comprehensive evaluation of the PEE system in the Three Gorges Reservoir Area from 2000 to 2020, this study utilized the coupling coordination degree model, gravity model, and obstacle degree model to empirically investigate the spatiotemporal evolution characteristics, spatial connectivity features, and main obstacle factors of the system's coupling coordination degree. [Results] (1) The comprehensive development level of the PEE system in the reservoir area had shown a gradual increase from 2000 to 2020. (2) During the study period, the coupling and coordination degree of the system was basically unchanged, with a not very high level of coordination. The type of coordination showed the spatial characteristics of "Southwest-Northeast" and "Central-North", with an overall benign upward development trend. (3) The spatial correlation of the coupling and coordination degree of the system in neighboring regions had a significant positive autocorrelation, the total spatial linkage was rising in general. the spatial linkage strength was weak, and it was gradually weakening with the increase of the geographic distance. (4) The influence of each factor on the system's development had a convergence, with the economic and demographic system being the main constraining subsystems, and the obstacle degree of the environmental system was increasing year by year. [Conclusion] The overall level of coupled and coordinated development of the PEE system in the reservoir area was improving, and regional differences were narrowing. In the future, the focus should be on the optimization of a single system to the coordination of multiple systems, and adjustments should be made from both the perspectives of the system itself and regional synergy, in order to strengthen policy and institutional regulation and scientifically explore the development path. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Engineering Management / Gongcheng Guanli Xuebao is the property of Journal of Engineering Management Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Mining & Metallurgy (10057854) is the property of Beijing Research Institute of Mining & Metallurgy Technology Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Geography Teaching is the property of Geography Teaching Editorial Office, East China Normal University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The separation of galena and chalcopyrite has always been a difficult point in the field of mineral processing. The use of sulfuric acid pre oxidation can selectively inhibit the surface floatability of the lead mineral, so that the floatability of the two minerals is different, and the flotation separation is realized. In this study, the parameters of sulfuric acid pre oxidation flotation separation process for a copper lead bulk concentrate were systematically optimized. Firstly, the effects of key factors such as pre oxidized sulfuric acid concentration, temperature and time on the flotation of copper lead bulk concentrate were analyzed by single factor test Secondly, the mathematical model between the influencing factors and the flotation index in the pre oxidation process was established by using the orthogonal test analysis method. By solving the model, the optimal pre oxidation conditions were obtained as follows: sulfuric acid concentration 5 mol/L, time 40 min, temperature 100 °C. Finally, a locked cycle test of pre oxidation flotation of the bulk concentrate was carried out under the above conditions, and a copper concentrate with Cu grade of 18. 03% and Cu recovery of 94. 52% was obtained. The lead concentrate has a good index of Pb grade of 47. 12% and Pb recovery of 91. 29%. The separation effect of copper and lead is remarkable, which provides a certain reference for the efficient flotation separation of copper lead sulfide bulk concentrate. [ABSTRACT FROM AUTHOR]

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Aim To investigate the risk factors of death after acute Stanford type A aortic dissection (ATAAD) complicated with malperfusion syndrome (MPS). Methods 244 patients with ATAAD complicated with MPS who admitted to Nanchong Central Hospital from June 2020 to June 2023 were selected as the study objects. The postoperative survival of the patients was followed up and they were classified into survival group (156 cases) and death group (88 cases). After propensity score matching (PSM) was applied in 1 ∶ 1 matching, there were 54 cases in both groups. Univariate and Logistic regression analysis was performed to analyze the risk factors of postoperative death in patients with ATAAD complicated with MPS. Area under curve (AUC) of receiver operating characteristics (ROC) was used to analyze the prognosis of ATAAD complicated with MPS. The prediction model was established by using the regression equation y=1-1/(1+e-z) and the stability of the model was verified by cross-checking method. Results After matching, compared with the survival group (n =54), in the death group (n =54), the proportion of sex (male), the proportion of alcohol consumption, acute physiology and chronic health status Ⅱ (APACHE Ⅱ) score, sequential organ failure (SOFA) score, alanine aminotransferase (ALT), aspartate aminotransferase (AST), total serum bilirubin (TSB), cholinesterase, serum creatinine (SCr), blood urea nitrogen (BUN), N-terminal pro-brain natriuretic peptide (NT-proBNP), D-dimer (D-D), white blood cell (WBC), neutrophile granulocyte (NEU), fibrinogen degradation product (FDP), platelet (PLT), fibrinogen (FIB), C-reactive protein (CRP), hypersensitive troponin, operation time, ICU stay time, ventilator stay time, hospital stay, distal extremity hypoperfusion, renal hypoperfusion were significantly increased (P<0. 05). Logistic analysis displayed that gender (male), history of drinking, NT-proBNP≥271. 86 ng/L, D-D≥0. 74 mg/L and NEU≥13. 06× 109 L-1 were independent risk factors in ATAAD patients complicated with MPS for postoperative death (P<0. 05). The combination of NT-proBNP, D-D, gender (male), alcohol drinking history and NEU (referred to as "five factors") had the highest value in predicting ATAAD patients with MPS. The AUC of its ROC curve was 0. 979 (95% CI: 0. 937 ~ 0. 984), the sensitivity was 94. 3%, and the specificity was 91. 8%, which was higher than the independent predictor. The best critical value predicted by the five factors was 5. 02. The survival rate of the group >5. 02 was significantly higher than that of the group ≤5. 02. Log Rank test P<0. 01. A prediction model was established based on the important factors of postoperative death in ATAAD patients with MPS. The results showed that the model had good prediction accuracy. Conclusion NT-proBNP≥271. 86 ng/L, D-D≥0. 74 mg/L, gender (male), history of alcohol consumption, and NEU≥×109 L-1 were independent risk factors for long-term prognosis in patients with ATAAD combined with MPS, and their combined application could effectively increase the accuracy of prognosis assessment. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Agricultural Resources & Environment / Nongye Ziyuan yu Huanjing Xuebao is the property of Journal of Agricultural Resources & Environment Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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【目的】探讨借助三维CT的术前规划在个性化手术工具（PSI）辅助初次人工膝关节表面置换中的应 用。【方法】54位患膝骨关节炎的患者依据随机、 “双盲”的方法分为传统工具（CI）组和PSI组，每组27位患者，进 行初次膝关节表面置换术。两组术前根据三维图像及截骨数据来选取假体大小。PSI组胫骨平台假体的旋转定 位依据形合度匹配，并允许假体边缘在一些部位有限超出截骨面边缘。CI组术中依据传统方法进行测量和截 骨。比较两组患者手术时间，调整假体大小的例次，后髁截骨量，术后X线平片情况，术后3个月、1年AKS评 分。【结果】两组手术时间无统计学差异；PSI组术中无需调整假体大小；CI组有8例所用假体与术前计划不同，均 小于术前依据三维CT的测量结果；CI组平均后髁截骨量大于PSI组。术后3个月PSI组患者AKS高于CI组；术 后1年两组AKS评分没有统计学差异。【结论】术前薄层CT扫描结果可用于术前截骨计划，有利于正确选择股骨 假体尺寸和位置。股骨和胫骨假体在一定部位有限超出截骨面边缘，不会增加术后患者不适感。使用解剖形态 的胫骨假体时，可以依据最佳覆盖原则确定胫骨假体的旋转定位。

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Science Technology & Engineering is the property of Chinese Society of Technology Economics and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)