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Sulforaphane is a phytochemical that has been reported to possess various biological activities such as antioxidant, anti-cancer, and anti-inflammatory. However, factors such as poor instability and thermal sensitivity of sulforaphane limit its application in different fields. Nanotechnology-based drug delivery systems offer the possibility of multidimensional applications of sulforaphane. By combining with nanotechnology, the bioavailability of sulforaphane can be improved and its clinical trials can be promoted. Based on the above characteristics, this paper presents a detailed overview of the specific mechanisms of action of different biological activities of sulforaphane, the characteristics of sulforaphane nanoparticles and their biological applications. Among them, it focuses on the overview of the characteristics of inorganic nanoparticles, organic nanoparticles and inorganic-organic composite nanoparticles applied for sulforaphane delivery, and summarizes the specific applications of sulforaphane nanoparticles according to their therapeutic diversity. In addition, the article gives an overview of the main issues and development prospects of sulforaphane nanoparticles, with a view to expanding the application fields of sulforaphane and injecting new impetus into the future development of food, health care, and medical science and technology. [ABSTRACT FROM AUTHOR]

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The experiment was to explore the effect of corn straw fermented by different strains on growth performance, serum biochemical index, immune function and meat quality of Siemental cattle. 100 healthy Simental bulls with similar weight were selected and randomly divided into four groups, with five replicates in each group and five cattle in each replicate. The Siemental cattle in control group were fed with basic diet + no bacteria corn straw. The Siemental cattle in group 1, group 2 and group 3 were fed with basic diet + 5% corn straw fermented by wood mold, yeast and lactic acid bacteria, respectively. The pre-test period was 5 d, and the formal test lasted for 60 d. The results showed that the terminal weight of Siementhal cattle in test group 3 was significantly higher than that in other groups (P<0.05), and the feed to gain ratio of Siementhal cattle in test group 3 was significantly lower than that in other groups (P<0.05). The total protein and glucose content in all the test groups were significantly higher than those in control group (P<0.05), and the test group 3 had the highest total protein and glucose content. The IgG and IgA content of all the test groups were higher than those in control group with no significant difference (P>0.05), and the test group 3 had the highest IgG and IgA content. The a* value and crude protein content of beef in all the test groups were significantly higher than those in control group (P<0.05), and the test group 3 had the highest a* value and crude protein content. The experiment indicates that adding 5% fermented corn straw to the diet of Simental cattle can promote the growth performance of Simontal cattle, increase the content of total protein and glucose in the blood, and improve immune function and meat quality. The corn straw fermented with lactic acid bacteria has the best effect. [ABSTRACT FROM AUTHOR]

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Tetracycline is widely used in animal husbandry and aquaculture to prevent bacterial infection and improve growth rate because of its broad-spectrum activity and low cost. Excessive use of tetracycline leads to antibiotic residues in food，which seriously threatens human health. Thiophenin T（ThT）can be embedded into a special nucleic acid structure，so that the fluorescence intensity is strongly excited to achieve signal output. In this paper，tetracycline aptamer can bind with G-rich sequence to form a double chain，but tetracycline preferentially binds with the aptamer when it exists. The G-rich sequence after unbound can fold itself to form a G-triplex structure，which enhances the fluorescence intensity of ThT. According to the good linear relationship between the target concentration and the fluorescence intensity of ThT，the quantitative detection of tetracycline can be acheieved. The method offers good linearity in the range of tetracycline concentration from 1 nmol/L-1 μmol/L 1 μ m，R2 is as high as 0.99，detection limit is 0.07 nmol/L，and detection can be completed within 25 min. Therefore，a visualization method based on G-triplex for double-stranded competitive internal cleavage has been developed and simple， rapid，sensitive，specific and low-cost detection of tetracycline is achieved. [ABSTRACT FROM AUTHOR]