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为了研究钢框架-型钢混凝土（SRC）自复位墙板结构的抗震性能，完成了钢框架-自复位SRC墙板子结构模型的低周往复加载试验，以研究其工作机理和失效机制。提出了基于宏观单元的非线性分析模型，并利用试验结果验证模型的准确性，研究结果表明该非线性分析模型能较好地模拟自复位SRC墙板的非线性行为。分别建立6层和15层钢框架-自复位SRC墙板结构的整体模型并进行增量动力时程分析（IDA）。以地面峰值加速度为地震动强度指标，以最大层间位移角为损伤指标，根据IDA结果得到不同极限状态下的易损性曲线，建立地震易损性矩阵，并对不同极限状态下结构的损伤风险进行了评估，研究表明：6层和15层钢框架-自复位SRC墙板结构在50年内的倒塌概率分别为0.138%和0.095%，远小于FEMA 750规定的1%，由此可见，钢框架-自复位SRC墙板结构抗震性能较好，并具备良好的抗地震倒塌能力。

文章阐述了光模块突发接收误码测试的基本原理。根据吉比特无源光网络（GPON）系统上行数据的特点,提出了一种新的突发数据提取方法及其关键技术,并设计了实现突发测试的逻辑框图、逻辑时序图及电路。采用该测试系统对GPON光线路终端（OLT）光模块进行了测试,结果表明该系统操作简单,可靠性高,能够满足GPON OLT光模块性能测试的需要。

文章报道一种10 Gbit/s SFP+（加强型小型化可热插拔）光收发模块。该模块由TOSA（光发送子系统）、ROSA（光接收子系统）和控制电路组成,实现了SFP+的智能化控制和模块状态监测功能。依照SFF-8431（多源协议）对该模块进行了测试,结果表明,该模块满足10 Gbit/s以太网的应用要求,且最高可支持11.3 Gbit/s的速率。

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Advances in Earth Science (1001-8166) is the property of Advances in Earth Science Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Architecture & Civil Engineering is the property of Chang'an Daxue Zazhishe and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Rehabilitation Medicine is the property of China Association of Rehabilitation Medicine, China-Japan Friendship Hospital and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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糖尿病的发病率和患病率逐年升高, 是全球公共卫生的主要威胁。早期强化降糖能够 延缓疾病进展, 降低糖尿病并发症的发生风险。"代谢记忆"假说为早期强化代谢控制所带来的持久益 处提供了解释。胰高糖素样肽-1受体激动剂（GLP-1RA）被证实在2型糖尿病人群中可以有效改善血 糖, 降低体重, 相关心血管结局研究也证实大多数GLP-1RA能够显著降低心血管不良事件风险。该 文汇总归纳糖尿病早期干预治疗与GLP-1RA在早期降糖以及心肾获益方面的最新临床研究进展, 解 析GLP-1RA降糖及改善心血管终点的机制, 为临床提供参考。. [ABSTRACT FROM AUTHOR]

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Objective To analyze the clinical features, diagnosis and treatment of 11 patients with livedoid vasculopathy. Methods The general data, clinical manifestations, dermoscopic findings, histopathological features and prognosis of diagnosis and treatment of 11 patients with livedoid vasculopathy were retrospectively analyzed. Results Among the 11 patients, there were 1 male and 10 females. The calf, ankle and dorsum were involved with erythema, purpura and blisters, followed by ulceration, ivory-white atrophy, scar and pigmentation after recovery. Five cases were severe in summer and mild in winter, and 6 cases were misdiagnosed as vasculitis and other diseases. Histopathological examination revealed fibrinoid necrosis and/or vascular embolism in dermal vessels. Five patients had common features of livedoid vasculopathy by dermoscopy. There was no recurrence in 6 patients who received combined treatment with oral glucocorticoid, rivaroxaban, dipyridamole, and aspirin, but 3 of 5 patients relapsed after single-drug treatment. Conclusions Livedoid vasculopathy is easy to be misdiagnosed clinically. When the ankle and dorsum of the foot are involved, the disease should be highly vigilant. Diagnosis is mainly based on histopathological changes, and dermoscopy can improve the diagnostic accuracy. Single-drug treatment is prone to recurrence, and combined drug treatment is effective. [ABSTRACT FROM AUTHOR]

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BACKGROUND: Primary knee osteoarthritis is one of the most common chronic diseases among the elderly, which brings a heavy burden on society and families. Current clinical treatments only focus on surgeries such as total knee replacement, but it is difficult to prevent cartilage tissue degeneration at an early stage. The formation mechanism of knee osteoarthritis, especially the influence of inflammation in disease progression, has been reported to some extent, but its specific mechanism is still unclear. OBJECTIVE: To investigate the differentially expressed circRNA sites of primary knee osteoarthritis and rheumatoid arthritis and their effects on the pathogenesis of the disease. METHODS: In this study, we collected the synovial tissues from eight patients with primary knee osteoarthritis and two patients with rheumatoid arthritis (control group). The expression profile of circRNAs in the tissue was detected by RNA-seq technique, trying to find the differentially expressed genes and key biological function pathways. RESULTS AND CONCLUSION: Compared with patients with rheumatoid arthritis, 185 differentially expressed circRNAs were detected in patients with knee osteoarthritis, of which 14 were up-regulated and 171 were down-regulated. Through the pathway enrichment and functional annotation of these target genes, a variety of enrichment pathways were identified, including protein H3-K36 dimethylation, glycosphingolipid biosynthesis process, and positive regulation of Toll-like receptor 9 signaling pathway. Based on the above sequencing results, a circRNA-miRNA interaction network was created, contributing to understanding the effect of differentially expressed circRNAs. In this study, we determined the differential expression of inflammation-related circRNAs in synovial tissue and the control group. These differentially expressed transcripts may elucidate the effect of circRNA and its relationship network in synovial tissue on the progression of osteoarthritis. Findings from this study will be helpful to explore the pathogenesis and key therapeutic targets of osteoarthritis. [ABSTRACT FROM AUTHOR]

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