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Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The impact of climate change is becoming increasingly urgent and severe. Meanwhile, global geopolitical situation remains tense, fueled by challenges such as economic downturn, energy crisis, debt crisis in developing countries, and intensifying competition among major powers. Against this backdrop, global climate governance faces multiple difficulties, and the leading channel for multilateral climate governance under the United Nations Framework Convention on Climate Change (UNFCCC) has seen setbacks. With carbon neutrality forming a broad political consensus around the world, different countries have launched a new round of competition and cooperation on green technology and industry, energy transformation and infrastructure construction in developing countries. Major country competition has shifted from competition on carbon emission space and development rights under the UNFCCC over the years to competition for climate-related rules, green standards, and the dominant position in the green industry chain. The scope of greenhouse gas emissions reduction has been further expanded to the international aviation and shipping industry, and nonstate actors are playing an increasingly important role in climate governance. In the future, China should continue to adhere to the multilateral process of global climate governance under the UNFCCC, actively participate in and lead the formulation of green rules, advocate the principle of “Common but Differentiated Responsibilities”, proactively assume international obligations commensurate with its national conditions, development stages, and capacities, and work with all parties to promote global climate governance in an effort to build a community with a shared future for mankind. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Forensic Medicine / Fayixue Zazhi is the property of Journal of Forensic Medicine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To observe the effects of gastrodin on the abnormal behaviors and the expressions of janus kinase 2-signal transducer and transcription activator 3 (JAK2-STAT3) signaling pathway in depression mice model. Methods: Forty male Kunming mice, were randomly divided into normal and model groups. After 4 weeks CUMS stimulation, the behavioral changes of mice were detected in week 6 to verify the modeling effect. The model was then composed of three subgroups: CUMS+saline, CUMS+fluoxetine and CUMS+gastrodin group, CUMS stimulation continued during weeks 7-8. At the same time, three subgroups of mice were injected intraperitoneally. The behavior test was carried out again in week 9. Mouse brain tissue was HE stained and Western blot. Results: The results of week 6 showed that, compared to control group, CUMS stimulation significantly decreased the weight change (P<0.001), increased the immobility time in tail suspension and forced swimming test (P<0.001, P<0.001) and decreased the percentage of sucrose intake(P<0.001). At week 9, the results showed: compared to CUMS+saline group, CUMS+fluoxetine group and CUMS+gastrodin group significantly increased weight change (P<0.001, P<0.001), decreased the immobility time in forced swimming test (P<0.001, P<0.001), decreased immobility the time in tail suspention test (P<0.01, P<0.01) and increased the percentage of sucrose intake(P<0.001, P<0.001). Compared with CUMS+saline group, the expression of JAK2, STAT3 IL-1茁 in CUMS+gastrodin group decreased significantly(P<0.01, P<0.01, P<0.05); The results of HE staining showed that, the morphology of neurons in CUMS+saline group was changed, the cell structure was not clear, the nucleus shrank and dyed deeply, and the morphology of neurons in CUMS+gastrodin group was improved compared to that in CUMS+saline group. Conclusion: Gastrodin could effectively improve the CUMS induced depressive behaviors in mice, and its effect might be related to the expressions of key proteins in JAK2-STAT3 signaling pathway. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Clean Coal Technology is the property of Clean Coal Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)